Page last updated: 2024-09-04

5-propyl-2'-deoxyuridine and fluorouracil

5-propyl-2'-deoxyuridine has been researched along with fluorouracil in 1 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies
(5-propyl-2'-deoxyuridine)
Trials
(5-propyl-2'-deoxyuridine)
Recent Studies (post-2010)
(5-propyl-2'-deoxyuridine)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
90045,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomy5-propyl-2'-deoxyuridine (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE1

Other Studies

1 other study(ies) available for 5-propyl-2'-deoxyuridine and fluorouracil

ArticleYear
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
    Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7

    Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship

2007