Page last updated: 2024-09-05

5-o-methylembelin and embelin

5-o-methylembelin has been researched along with embelin in 2 studies

*embelin: from Embelia fruit (Myrsinaceae) [MeSH]

*embelin: from Embelia fruit (Myrsinaceae) [MeSH]

Compound Research Comparison

Studies
(5-o-methylembelin)
Trials
(5-o-methylembelin)
Recent Studies (post-2010)
(5-o-methylembelin)
Studies
(embelin)
Trials
(embelin)
Recent Studies (post-2010) (embelin)
5032371169

Protein Interaction Comparison

ProteinTaxonomy5-o-methylembelin (IC50)embelin (IC50)
Prostaglandin E synthaseHomo sapiens (human)0.2
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)1.224
E3 ubiquitin-protein ligase XIAPHomo sapiens (human)4.1
Macrophage-expressed gene 1 proteinHomo sapiens (human)0.21
Histone acetyltransferase KAT2BHomo sapiens (human)7.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, F; Hong, Z; Hu, L; Huang, M; Lei, M; Lin, Z; Zhang, G1
Barz, D; Bruno, F; D'Agostino, B; De Rosa, M; Filosa, R; Krauth, V; Peduto, A; Petronzi, C; Roviezzo, F; Schaible, AM; Spaziano, G; Weinigel, C; Werz, O1

Other Studies

2 other study(ies) available for 5-o-methylembelin and embelin

ArticleYear
Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1).
    Bioorganic & medicinal chemistry letters, 2014, May-15, Volume: 24, Issue:10

    Topics: Benzoquinones; Binding Sites; Drug Design; Models, Molecular; Plasminogen Activator Inhibitor 1; Structure-Activity Relationship

2014
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes.
    European journal of medicinal chemistry, 2015, Apr-13, Volume: 94

    Topics: Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Benzoquinones; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Neutrophils; Prostaglandin-E Synthases; Structure-Activity Relationship

2015