5-nitroindazole has been researched along with indazoles in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 5 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acuña-Castroviejo, D; Claramunt, RM; Elguero, J; Escames, G; López, C; Pérez-Medina, C; Pérez-Torralba, M | 1 |
| Aguilera, B; Arán, V; Jullian, C; Morales-Montecinos, J; Olea-Azar, C; Rodriguez, J; Zapata-Torres, G | 1 |
| Arán, VJ; Boiani, L; Cerecetto, H; Gerpe, A; González, M; Maya, JD; Morello, JA; Nakayama, H; Rojas de Arias, A; Sanabria, L; Serna, E; Torres de Ortiz, S; Vera de Bilbao, N; Yaluff, G | 1 |
| Aguirre, G; Arán, VJ; Cerecetto, H; Gerpe, A; González, M; Kemmerling, U; Maya, JD; Olea-Azar, C; Piro, OE; Rodríguez, J | 1 |
| Arán, VJ; Jullian, C; Olea-Azar, C; Pérez-Cruz, F; Rodriguez, J | 1 |
| Arán, VJ; Boiani, L; Carrasco-Pozo, C; Cerecetto, H; Cosoy, HS; González, M; Lavaggi, ML; Maya, JD; Olea-Azar, C; Rodríguez, J | 1 |
| Arán, VJ; Diaz-Urrutia, C; Folch-Cano, C; Olea-Azar, C | 1 |
| Arán, VJ; Doménech, A; García-España, E; Montoya, N; Muro, B; Navarro, P | 1 |
| Guillén, H; Herraiz, T | 1 |
| Herraiz, T | 1 |
| Arán, VJ; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A | 1 |
| Arán, VJ; Marín, C; Muro, B; Navarro, P; Ramírez-Macías, I; Reviriego, F; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Arán, VJ; Escario, JA; Gómez-Barrio, A; Ibáñez-Escribano, A; Nogal-Ruiz, JJ | 1 |
| Amaya-Guio, J; Grillo-Ardila, CF; Martinez-Velasquez, MY; Sierra-Barrios, EM; Viveros-Carreño, DA | 1 |
| Cruces-Blanco, C; García-Campaña, AM; Hernández-Mesa, M | 1 |
| Eckmann, L; Fokin, VV; Ghassemian, M; Ihara, S; Kalisiak, J; Korthals, KA; Lauwaet, T; Le, C; Miyamoto, Y; Sharpless, KB; Smith, DK | 1 |
| Arán, VJ; Batista, DDGJ; Batista, MM; Cumella, J; da Silva, CF; de Oliveira, GM; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Peres, RB; Silva da Gama Nefertiti, A; Soeiro, MNC | 1 |
| Arán, VJ; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Ibáñez-Escribano, A; Nogal-Ruiz, JJ; Reviriego, F; Vela, N | 1 |
| Arán, VJ; Marín, C; Martín-Escolano, R; Pérez-Cordón, G; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Arán, VJ; de Castro, S; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Ibáñez-Escribano, A | 1 |
1 review(s) available for 5-nitroindazole and indazoles
| Article | Year |
|---|---|
Antibiotic treatment for the sexual partners of women with bacterial vaginosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Female; Humans; Indazoles; Lincosamides; Male; Metronidazole; Middle Aged; Randomized Controlled Trials as Topic; Recurrence; Secondary Prevention; Sexual Partners; Time Factors; Tinidazole; Vaginosis, Bacterial | 2016 |
19 other study(ies) available for 5-nitroindazole and indazoles
| Article | Year |
|---|---|
Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation.
Topics: Animals; Enzyme Inhibitors; Halogenation; Heme; Indazoles; Male; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2009 |
Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative with cyclodextrins.
Topics: Computer Simulation; Cyclodextrins; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phase Transition; Reference Standards; Solubility; Water | 2008 |
In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles.
Topics: Animals; Drug Evaluation, Preclinical; In Vitro Techniques; Indazoles; Leishmania; Mice; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
Study of 5-nitroindazoles' anti-Trypanosoma cruzi mode of action: electrochemical behaviour and ESR spectroscopic studies.
Topics: Animals; Antiprotozoal Agents; Electrochemistry; Electron Spin Resonance Spectroscopy; Indazoles; Trypanosoma cruzi | 2009 |
Molecular encapsulation of 5-nitroindazole derivatives in 2,6-dimethyl-beta-cyclodextrin: electrochemical and spectroscopic studies.
Topics: beta-Cyclodextrins; Drug Delivery Systems; Electrochemistry; Electron Spin Resonance Spectroscopy; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Solubility; Trypanocidal Agents | 2009 |
New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and mechanism of action studies.
Topics: Chagas Disease; Crystallography, X-Ray; DNA, Protozoan; HeLa Cells; Humans; Indazoles; Nitroimidazoles; Oxidation-Reduction; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
ESR and electrochemical study of 1,2-disubstituted 5-nitroindazolin-3-ones and 2-substituted 3-alkoxy-5-nitro-2H-indazoles: reactivity and free radical production capacity in the presence of biological systems.
Topics: Animals; Anions; Electrochemistry; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Humans; Indazoles; Microsomes; Molecular Structure; Oxidation-Reduction; Reactive Nitrogen Species; Trypanosoma cruzi | 2010 |
Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings.
Topics: Amphetamine; Amphetamines; Carbon; Dopamine; Electrochemical Techniques; Electrodes; Indazoles; Mescaline; Methamphetamine; Phenethylamines; Psychotropic Drugs | 2010 |
Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Antioxidants; Carbolines; Chromatography, High Pressure Liquid; Harmine; Humans; Indazoles; Mass Spectrometry; Methylene Blue; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Selegiline | 2011 |
Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Carbolines; Chromatography, High Pressure Liquid; Clorgyline; Enzyme Assays; Harmine; Humans; Indazoles; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Nicotiana; Oxidation-Reduction; Pyridinium Compounds; Recombinant Proteins; Selegiline; Smoke; Vitamin K 3 | 2012 |
Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles.
Topics: Animals; Cell Line; Indazoles; Mice; Trypanocidal Agents; Trypanosoma cruzi | 2014 |
In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles.
Topics: Acetates; Alanine; Animals; Antiprotozoal Agents; Glycine; In Vitro Techniques; Indazoles; Lactic Acid; Leishmania braziliensis; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Transmission; Mitochondria; Organelles; Pyruvic Acid; Succinic Acid | 2015 |
In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives.
Topics: Alcohols; Animals; Antitrichomonal Agents; Cell Survival; Chlorocebus aethiops; Computer Simulation; Indazoles; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trichomonas Infections; Trichomonas vaginalis; Vero Cells | 2016 |
Simple and rapid determination of 5-nitroimidazoles and metabolites in fish roe samples by salting-out assisted liquid-liquid extraction and UHPLC-MS/MS.
Topics: Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Eggs; Food Contamination; Indazoles; Liquid-Liquid Extraction; Reproducibility of Results; Sodium Chloride; Tandem Mass Spectrometry | 2018 |
Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.
Topics: Animals; Antiparasitic Agents; Click Chemistry; Disease Models, Animal; Drug Discovery; Female; Giardia lamblia; Giardiasis; Indazoles; Intestine, Small; Male; Mice, Inbred C57BL; Parasite Load; Protein Binding; Proteomics; Protozoan Proteins | 2020 |
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant
Topics: Animals; Cell Line; Chagas Disease; Drug Resistance; Drug Therapy, Combination; Humans; Indazoles; Mice; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi | 2020 |
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles.
Topics: Antiparasitic Agents; Dose-Response Relationship, Drug; Drug Resistance; Indazoles; Molecular Structure; Structure-Activity Relationship; Trichomonas Infections; Trichomonas vaginalis | 2021 |
5-Nitroindazole derivatives as potential therapeutic alternatives against Acanthamoeba castellanii.
Topics: Acanthamoeba castellanii; Animals; Chlorocebus aethiops; Humans; Indazoles; Trophozoites; Vero Cells | 2022 |
5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents.
Topics: Chagas Disease; Humans; Indazoles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2022 |