5-nitro-2'-deoxyuridine has been researched along with thymidine in 3 studies
| Studies (5-nitro-2'-deoxyuridine) | Trials (5-nitro-2'-deoxyuridine) | Recent Studies (post-2010) (5-nitro-2'-deoxyuridine) | Studies (thymidine) | Trials (thymidine) | Recent Studies (post-2010) (thymidine) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 33,410 | 241 | 1,117 |
| Protein | Taxonomy | 5-nitro-2'-deoxyuridine (IC50) | thymidine (IC50) |
|---|---|---|---|
| Thymidine kinase | Macacine alphaherpesvirus 1 | 4.1 | |
| Thymidine kinase, cytosolic | Homo sapiens (human) | 0.614 | |
| Thymidine kinase | Human alphaherpesvirus 1 strain SC16 | 1 | |
| Sterol O-acyltransferase 1 | Cricetulus griseus (Chinese hamster) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashton, SE; Barry, ST; Bryce, RA; Cole, C; Douglas, KT; Edwards, PN; Freeman, S; Gbaj, A; Jaffar, M; Luke, RW; Page, KM; Reigan, P; Stratford, IJ | 1 |
| Bryce, RA; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ | 1 |
| De Clercq, E; Descamps, J; Huang, GF; Torrence, PF | 1 |
3 other study(ies) available for 5-nitro-2'-deoxyuridine and thymidine
| Article | Year |
|---|---|
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Availability; Escherichia coli; Humans; Imidazoles; Mice; Models, Molecular; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Structure-Activity Relationship; Thymidine Phosphorylase; Uracil | 2005 |
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Prodrugs; Spectrophotometry, Infrared; Thymidine Phosphorylase; Xanthine Oxidase | 2008 |
5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.
Topics: Antiviral Agents; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Drug Interactions; Methyltransferases; Thymidine; Thymidylate Synthase | 1978 |