5-nitro-2'-deoxyuridine has been researched along with 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride in 2 studies
| Studies (5-nitro-2'-deoxyuridine) | Trials (5-nitro-2'-deoxyuridine) | Recent Studies (post-2010) (5-nitro-2'-deoxyuridine) | Studies (5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride) | Trials (5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride) | Recent Studies (post-2010) (5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 12 | 0 | 6 |
| Protein | Taxonomy | 5-nitro-2'-deoxyuridine (IC50) | 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride (IC50) |
|---|---|---|---|
| Thymidine phosphorylase | Escherichia coli K-12 | 0.0227 | |
| Thymidine phosphorylase | Homo sapiens (human) | 0.0314 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashton, SE; Barry, ST; Bryce, RA; Cole, C; Douglas, KT; Edwards, PN; Freeman, S; Gbaj, A; Jaffar, M; Luke, RW; Page, KM; Reigan, P; Stratford, IJ | 1 |
| Bryce, RA; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ | 1 |
2 other study(ies) available for 5-nitro-2'-deoxyuridine and 5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride
| Article | Year |
|---|---|
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Availability; Escherichia coli; Humans; Imidazoles; Mice; Models, Molecular; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Structure-Activity Relationship; Thymidine Phosphorylase; Uracil | 2005 |
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Prodrugs; Spectrophotometry, Infrared; Thymidine Phosphorylase; Xanthine Oxidase | 2008 |