Compounds > 5-n-acetylardeemin
Page last updated: 2024-09-03

5-n-acetylardeemin and pyrimidinones

5-n-acetylardeemin has been researched along with pyrimidinones in 8 studies

Compound Research Comparison

Studies
(5-n-acetylardeemin)		Trials
(5-n-acetylardeemin)		Recent Studies (post-2010)
(5-n-acetylardeemin)		Studies
(pyrimidinones)		Trials
(pyrimidinones)		Recent Studies (post-2010) (pyrimidinones)
8036,0596042,692

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Humphrey, PE; Jackson, M; Kadam, S; Karwowski, JP; Kohl, WL; McAlpine, JB; Poddig, JB; Rasmussen, RR; Scherr, MH1
Hill, P; Hochlowski, JE; McAlpine, JB; Mullally, MM; Spanton, SG; Whittern, DN1
Bornmann, W; Chan, D; Chou, TC; Danishefsky, SJ; Depew, KM; Helfrich, B; Safer, ML; Zatorska, D; Zatorski, A; Zheng, YH1
Avendaño, C; Corzo-Suárez, R; Espada, M; Gago, F; García-Granda, S; Martín-Santamaría, S; Rzepa, HS1
Ban, N; Higuchi, K; Iizuka, T; Kawasaki, T; Kumakura, YS; Murasaki, K; Takiguchi, S1
Qin, Y; Song, H; Zhang, D1
Li, DX; Liao, LC; Lin, Y; Qin, Y; Song, H; Wang, X; Yan, YY; Yang, L; Zhao, C; Zheng, XL1
Hayashi, D; Higuchi, K; Iizuka, T; Ikegami, Y; Inoue, Y; Kawasaki, T; Matsubayashi, Y; Tsukioka, N1

Other Studies

8 other study(ies) available for 5-n-acetylardeemin and pyrimidinones

ArticleYear
5-N-acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. I. Taxonomy and fermentation of the producing organism and biological activity.
    The Journal of antibiotics, 1993, Volume: 46, Issue:3

    Topics: Antibiotics, Antineoplastic; Aspergillus; Chromatography, High Pressure Liquid; Drug Interactions; Drug Resistance, Microbial; Fermentation; Heterocyclic Compounds; Humans; Pyrimidinones; Tumor Cells, Cultured; Vinblastine

1993
5-N-acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. II. Isolation and elucidation of the structure of 5-N-acetylardeemin and two congeners.
    The Journal of antibiotics, 1993, Volume: 46, Issue:3

    Topics: Antibiotics, Antineoplastic; Aspergillus; Drug Resistance, Microbial; Heterocyclic Compounds; Humans; Magnetic Resonance Spectroscopy; Pyrimidinones; Tumor Cells, Cultured

1993
Reversal of anticancer multidrug resistance by the ardeemins.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jul-07, Volume: 95, Issue:14

    Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation, Neoplastic; Humans; Indoles; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Pyrimidinones; Tumor Cells, Cultured; Vinblastine

1998
Diastereoselective reactions in glycine templates containing an ent-ardeemin fragment.
    The Journal of organic chemistry, 2002, Apr-05, Volume: 67, Issue:7

    Topics: Alkylation; Chemistry, Organic; Crystallography, X-Ray; Glycine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Pyrazines; Pyrimidinones; Quinazolines; Stereoisomerism

2002
Total syntheses of (-)-fructigenine A and (-)-5-N-acetylardeemin.
    The Journal of organic chemistry, 2010, Feb-19, Volume: 75, Issue:4

    Topics: Alkaloids; Catalysis; Crystallography, X-Ray; Cyclization; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Oxidation-Reduction; Pyrimidinones; Stereoisomerism

2010
Total synthesis of indoline alkaloids: A cyclopropanation strategy.
    Accounts of chemical research, 2011, Jun-21, Volume: 44, Issue:6

    Topics: Alkaloids; Biological Products; Carbazoles; Cyclization; Cyclopropanes; Heterocyclic Compounds, 4 or More Rings; Indoles; Models, Chemical; Pyrimidinones; Stereoisomerism; Vinca Alkaloids

2011
[Reversal effect and its mechanism of (- )-5-N-acetylardeemin on adriamycin resistance in multidrug-resistant cancer cells A549/Adr and MCF-7/Adr].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:6

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Pyrimidinones

2014
Synthesis and ABCG2 inhibitory evaluation of 5-N-acetylardeemin derivatives.
    Bioorganic & medicinal chemistry, 2015, May-01, Volume: 23, Issue:9

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neoplasm Proteins; Pyrimidinones; Structure-Activity Relationship

2015