Page last updated: 2024-08-16

5-methylurapidil and wb 4101

5-methylurapidil has been researched along with wb 4101 in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.56)	18.7374
1990's	48 (75.00)	18.2507
2000's	14 (21.88)	29.6817
2010's	1 (1.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Foglar, R; Horie, K; Obika, K; Ogawa, S; Sakamoto, A; Shibata, K; Tsujimoto, G	1
Bondinell, WE; Hieble, JP; Ruffolo, RR	1
Ballard, S; Blagg, J; Fox, D; Kenny, B	1
Chang, DJ; Clarke, DE; Daniels, DV; Ford, AP; Gever, JR; Jasper, JR; Lesnick, JD	1
Bach, C; Bhakta, S; Chan, HW; Chang, DJ; Chang, TK; Clarke, DE; Daniels, DV; Eglen, RM; Ford, AP; Jasper, JR; Khare, R; Kosaka, AH; Lesnick, JD; Salazar, FH; Shieh, IS; Yamanishi, SS	1
Gaivin, RJ; Gonzalez-Cabrera, P; Perez, DM; Ross, SA; Waugh, DJ; Yun, J; Zuscik, MJ	1
Pedretti, A; Testa, B; Villa, L; Vistoli, G	1
Etgen, AM; Karkanias, GB; Petitti, N	1
Kojima, C; Satoh, M; Takayanagi, I	2
Abel, PW; Dowd, FJ; Porter, JE	1
Hiramatsu, Y; Kigoshi, S; Muramatsu, I; Muraoka, R	1
Kowatch, MA; Miyamoto, A; Roth, GS; Villalobos-Molina, R	1
Endoh, M; Norota, I; Takanashi, M	1
García-Sáinz, JA; Torres-Márquez, ME; Villalobos-Molina, R	1
Atkinson, B; Minneman, KP	1
Han, CD; Minneman, KP	1
Moriya, M; Takayanagi, I	1
Hashimoto, K; Suzuki, E; Tamura, K; Tsujimoto, G	1
Gross, G; Hanft, G	1
Kow, LM; Pfaff, DW	1
Han, C; Yu, GS	1
Bigg, DC; Koek, W; Sleight, AJ	1
Adachi, M; Manita, S; Matsuda, T; Shigenobu, K; Tanaka, H	1
Aston, N; Chess-Williams, R; Couldwell, C	1
Chen, MZ; Han, QD; Yu, GS	1
Lepor, H; Meretyk, S; Shapiro, E; Tang, R	1
Lepor, H; Shapiro, E; Tang, R	1
Hatano, A; Koizumi, T; Komeyama, T; Takahashi, H; Takeda, M; Tamaki, M; Tsutsui, T	1
Docherty, JR; Kearns, S; O'Rourke, M	1
Hayashi, H; Hiraoka, Y; Muramatsu, I; Ohmura, T; Sakamoto, S	1
Costain, WJ; Desautels, M; Mainra, R; Sulakhe, PV	1
Aghajanian, GK; Marek, GJ	1
Chess-Williams, R; Furukawa, K; Uchiyama, T	1
Benoit, JN; Gao, H; Korthuis, RJ	1
Osnes, JB; Sandnes, D; Skomedal, T; Viko, H	1
Anyukhovsky, EP; Danilo, P; Guo, SD; Rosen, MR	1
Han, C; Xu, K; Zhang, Y	1
Badia, A; Giraldo, J; Tabernero, A; Vila, E; Vivas, NM	1
Chiba, T; Fukutomi, J; Hattori, K; Maruyama, K; Nagatomo, T; Takeda, M; Yamaguchi, M	1
Hussain, MB; Marshall, I	2
Kocić, I; Korolkiewicz, KZ	1
Hasegawa, Y; Ono, H; Wada, T	1
Kadavil, EA; Oriowo, MA; Yousif, M	1
Avkiran, M; Yasutake, M; Yokoyama, H	1
Foster, HE; Latifpour, J; Nishi, K; Saito, M; Weiss, RM; Yoshida, M	1
Hattori, K; Makara, Y; Maruyama, K; Nagatomo, T; Ohnuki, T; Suzuki, M; Tsuchiya, M; Watanabe, K	1
García-Sáinz, JA; Torres-Padilla, ME	1
Hiraoka, Y; Kato, H; Morikawa, K; Muramatsu, I; Nagata, O; Ohmura, T; Oshita, M; Taniguchi, T; Watanabe, Y	1
Davies, MG; Hagen, PO; Huynh, TT	1
Arias-Montaño, JA; Berger, VA; Soria-Jasso, LE; Young, JM	1
Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K	1
Hillier, C; Jarajapu, YP; MacDonald, A	1
Koike, K; Yamamoto, Y	2
Dyer, DC; Ioudina, MV	1
Horinouchi, T; Koike, K; Shibano, M; Tanaka, Y; Yamamoto, Y	1
Koss, MC; Yu, Y	1
Ducza, E; Falkay, G; Gáspár, R; Mihályi, A	1
Chen, K; Chen, M; Han, C; Lu, Z; Song, Y; Yan, J; Zhang, Y	1
Doze, VA; Hillman, KL; Porter, JE	1
Clair, DK; García-Cazarín, ML; Piascik, MT; Smith, JL	1
Bockman, CS; Dang, HK; Gruber, DD; Scofield, MA; Wangemann, P; Witt, KM	1

Reviews

2 review(s) available for 5-methylurapidil and wb 4101

Article	Year
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1995
Pharmacological options in the treatment of benign prostatic hyperplasia. Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9 Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship	1997

Article

Year

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.

Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1995

Pharmacological options in the treatment of benign prostatic hyperplasia.

Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1997

Other Studies

62 other study(ies) available for 5-methylurapidil and wb 4101

Article	Year
KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues. Molecular pharmacology, 1995, Volume: 48, Issue:2 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; CHO Cells; Clonidine; Cloning, Molecular; Cricetinae; Humans; Indoles; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Tamsulosin	1995
Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications for alpha1-adrenoceptor classification. British journal of pharmacology, 1997, Volume: 121, Issue:6 Topics: Adrenergic Agents; Animals; CHO Cells; Cloning, Molecular; Cricetinae; Humans; Inositol Phosphates; Radioligand Assay; Receptors, Adrenergic, alpha-1; Recombinant Proteins	1997
Molecular cloning, genomic characterization and expression of novel human alpha1A-adrenoceptor isoforms. FEBS letters, 1998, Jan-30, Volume: 422, Issue:2 Topics: Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Cricetinae; Gene Library; Humans; Inositol Phosphates; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostate; Radioligand Assay; Receptors, Adrenergic, alpha-1; Recombinant Proteins; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Transfection	1998
Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like antagonists. The Journal of biological chemistry, 2001, Jul-06, Volume: 276, Issue:27 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cell Membrane; Clonidine; Conserved Sequence; Cricetinae; Dihydropyridines; Dioxanes; Humans; Imidazoles; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Phenylalanine; Piperazines; Prazosin; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship	2001
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents	2005
Estradiol selectively regulates alpha 1B-noradrenergic receptors in the hypothalamus and preoptic area. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:10 Topics: Animals; Clonidine; Cyclic AMP; Dioxanes; Estradiol; Female; Hypothalamus; Ovariectomy; Piperazines; Prazosin; Preoptic Area; Rats; Receptors, Adrenergic	1992
Characterization of alpha 1-adrenoceptor subtypes labeled by [3H]prazosin in single cells prepared from rabbit thoracic aorta. European journal of pharmacology, 1992, Oct-06, Volume: 221, Issue:1 Topics: Animals; Aorta, Thoracic; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Methoxamine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spiperone	1992
Atypical alpha-1 adrenergic receptors on the rat parotid gland acinar cell. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3 Topics: Animals; Cerebral Cortex; Dioxanes; Male; Parotid Gland; Phenethylamines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tetralones	1992
5-Methylurapidil may discriminate between alpha 1-adrenoceptors with a high affinity for WB4101 in rat lung. British journal of pharmacology, 1992, Volume: 105, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; In Vitro Techniques; Lung; Male; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1992
Alpha 1-adrenoceptors in parotid cells: age does not alter the ratio of alpha 1A and alpha 1B subtypes. European journal of pharmacology, 1992, Jun-05, Volume: 226, Issue:2 Topics: Adrenergic alpha-Antagonists; Aging; Animals; Calcium; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Inosine Triphosphate; Male; Parotid Gland; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1992
Role of alpha 1A adrenoceptor subtype in production of the positive inotropic effect mediated via myocardial alpha 1 adrenoceptors in the rabbit papillary muscle: influence of selective alpha 1A subtype antagonists WB 4101 and 5-methylurapidil. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Piperazines; Rabbits; Receptors, Adrenergic, alpha; Stimulation, Chemical	1992
Pharmacological characterization of contractile responses induced by alpha 1-agonists, norepinephrine and clonidine, by selective antagonists of their subtypes in rabbit thoracic aorta. Japanese journal of pharmacology, 1992, Volume: 60, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rabbits	1992
Alpha 1-adrenoceptor subtypes in aorta (alpha 1A) and liver (alpha 1B). European journal of pharmacology, 1991, Mar-25, Volume: 206, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Liver; Membranes; Muscle, Smooth, Vascular; Phosphatidylinositols; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha	1991
Interaction of subtype-selective antagonists with alpha 1-adrenergic receptor-mediated second messenger responses in rat brain. Molecular pharmacology, 1991, Volume: 40, Issue:4 Topics: Adrenergic alpha-Antagonists; Alkylation; Animals; Brain; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Dihydropyridines; Dioxanes; Female; Inositol Phosphates; Male; Piperazines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Second Messenger Systems; Tritium	1991
Interaction of subtype-selective antagonists with alpha 1-adrenergic receptor binding sites in rat tissues. Molecular pharmacology, 1991, Volume: 40, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dioxanes; Kinetics; Male; Membranes; Phentolamine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors	1991
Alpha 1A-adrenoceptors in rabbit bronchus. European journal of pharmacology, 1991, Sep-17, Volume: 202, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Bronchi; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Piperazines; Rabbits; Receptors, Adrenergic, alpha	1991
Two pharmacologically distinct alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta: each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role. Molecular pharmacology, 1990, Volume: 38, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenethylamines; Phenoxybenzamine; Piperazines; Rabbits; Receptors, Adrenergic, alpha; Signal Transduction; Tetralones; Vasoconstriction	1990
Subclassification of alpha 1-adrenoceptor recognition sites by urapidil derivatives and other selective antagonists. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Dioxanes; Heart; In Vitro Techniques; Male; Myocardium; Phenethylamines; Phentolamine; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Yohimbine	1989
Functional analyses of alpha 1-adrenoceptor subtypes in rat hypothalamic ventromedial nucleus neurons. European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Hypothalamus, Middle; In Vitro Techniques; Neurons; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1	1995
Role of alpha 1A- and alpha 1B-adrenoceptors in phenylephrine-induced positive inotropic response in isolated rat left atrium. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Atrial Function; Binding, Competitive; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Inositol Phosphates; Male; Myocardial Contraction; Phenethylamines; Phenylephrine; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Tetralones	1994
Binding of antipsychotic drugs at alpha 1A- and alpha 1B-adrenoceptors: risperidone is selective for the alpha 1B-adrenoceptors. European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Binding Sites; Dioxanes; Hippocampus; In Vitro Techniques; Isoxazoles; Male; Phentolamine; Piperazines; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Risperidone; Spleen	1993
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate. British journal of pharmacology, 1995, Volume: 114, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine	1995
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra. Journal of autonomic pharmacology, 1994, Volume: 14, Issue:6 Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra	1994
A new alpha 1-adrenergic receptor subtype with low affinity for 5-methyl-urapidil but insensitive to chlorethylclonidine. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:6 Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Male; Myocardium; Phenethylamines; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetralones	1993
Alpha 1 adrenoceptor subtypes in the human prostate. The Journal of urology, 1993, Volume: 149, Issue:3 Topics: Adrenergic alpha-Antagonists; Aged; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Middle Aged; Phenethylamines; Piperazines; Prostate; Receptors, Adrenergic, alpha; Tetralones	1993
The alpha-adrenoceptor subtype mediating the tension of human prostatic smooth muscle. The Prostate, 1993, Volume: 22, Issue:4 Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Phenylephrine; Piperazines; Prostate; Receptors, Adrenergic, alpha	1993
Alpha 1-adrenoceptors in the human prostatic urethra are different from those of the human peripheral arteries. The Clinical investigator, 1993, Volume: 72, Issue:1 Topics: Arteries; Atropine; Clonidine; Dioxanes; Humans; Iliac Artery; Isometric Contraction; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Urethra; Yohimbine	1993
Investigation of the actions of chloroethylclonidine in rat aorta. British journal of pharmacology, 1995, Volume: 115, Issue:8 Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine	1995
Identification of alpha 1-adrenoceptor subtypes in the rabbit prostate. Journal of autonomic pharmacology, 1995, Volume: 15, Issue:4 Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Male; Muscle Contraction; Norepinephrine; Piperazines; Prazosin; Prostate; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-1	1995
Expressed alpha 1-adrenoceptors in adult rat brown adipocytes are primarily of alpha 1A subtype. Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:3 Topics: Adipocytes; Adipose Tissue, Brown; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cell Membrane; Dioxanes; Female; Piperazines; Rats; Receptors, Adrenergic, alpha-1	1996
Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons. European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3 Topics: Action Potentials; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxanes; In Vitro Techniques; Interneurons; Male; Norepinephrine; Oxathiins; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Risperidone; Spiperone	1996
Alpha 1B-adrenoceptor subtype mediating the phenylephrine-induced contractile response in rabbit corpus cavernosum penis. Japanese journal of pharmacology, 1996, Volume: 71, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Male; Penile Erection; Penis; Phenylephrine; Piperazines; Rabbits	1996
Hypoxia/reoxygenation selectively impairs alpha 1b-adrenoceptor function in small mesenteric arteries. The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1 Topics: Adrenergic alpha-Antagonists; Aerobiosis; Animals; Catalase; Clonidine; Dioxanes; Hypoxia; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Superoxide Dismutase; Yohimbine	1996
Alpha 1-adrenoceptor subtypes involved in increased 86Rb+ influx rate and inositol 1,4,5-trisphosphate mass in adult rat cardiomyocytes. European journal of pharmacology, 1997, Apr-04, Volume: 323, Issue:2-3 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Myocardium; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Rubidium Radioisotopes	1997
Responses to norepinephrine of normal and "ischemic" canine Purkinje fibers are consistent with activation of different alpha 1-receptor subtypes. Journal of cardiovascular electrophysiology, 1997, Volume: 8, Issue:6 Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminoquinolines; Animals; Dioxanes; Dogs; In Vitro Techniques; Microelectrodes; Myocardial Ischemia; Norepinephrine; Piperazines; Purkinje Fibers; Receptors, Adrenergic, alpha-1; Tetrahydroisoquinolines	1997
Alterations of cardiac alpha 1-adrenoceptor subtypes in hypothyroid rats. Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:7 Topics: Adrenergic alpha-Antagonists; Animals; Atrial Function; Binding, Competitive; Dihydropyridines; Dioxanes; DNA Primers; Heart Atria; Hypothyroidism; Male; Myocardial Contraction; Norepinephrine; Phenethylamines; Piperazines; Polymerase Chain Reaction; Protein Binding; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; RNA, Messenger; Tetralones; Thiouracil	1997
Use of the operational model of agonism and [3H]prazosin binding to assess altered responsiveness of alpha1-adrenoceptors in the vas deferens of spontaneously hypertensive rat. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Vas Deferens	1997
Two district alpha(1)-adrenoceptor subtypes in the human prostate: assessment by radioligand binding assay using 3H-prazosin. General pharmacology, 1996, Volume: 27, Issue:8 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Binding, Competitive; Dioxanes; Humans; In Vitro Techniques; Kinetics; Male; Nifedipine; Phentolamine; Piperazines; Prazosin; Prostate; Protein Binding; Radioligand Assay; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tritium	1996
Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery. British journal of pharmacology, 1997, Volume: 122, Issue:5 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Dioxanes; Dioxins; Dose-Response Relationship, Drug; In Vitro Techniques; Indoles; Indoramin; Isometric Contraction; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Oxathiins; Phenylephrine; Piperazines; Prazosin; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spiro Compounds; Vasoconstrictor Agents	1997
Negative inotropic action of alpha-1a adrenoceptor blocking agents: role of adenosine and ATP-sensitive K+ channels. General pharmacology, 1998, Volume: 30, Issue:3 Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Depression, Chemical; Dihydropyridines; Dioxanes; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Piperazines; Potassium Channels; Receptors, Adrenergic, alpha-1	1998
Characterization of alpha1-adrenoceptor subtypes in facilitation of rat spinal motoneuron activity. European journal of pharmacology, 1997, Dec-04, Volume: 340, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Bridged-Ring Compounds; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Male; Methoxamine; Motor Neurons; Norepinephrine; Oxazines; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Spinal Cord	1997
Heterogeneity of alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contractions of the rat superior mesenteric artery. Pharmacology, 1998, Volume: 56, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spiperone; Vasoconstriction; Vasoconstrictor Agents	1998
Alpha1-adrenergic stimulation of sarcolemmal Na+-H+ exchanger activity in rat ventricular myocytes: evidence for selective mediation by the alpha1A-adrenoceptor subtype. Circulation research, 1998, Jun-01, Volume: 82, Issue:10 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Dioxanes; Heart Ventricles; Humans; Imidazoles; Kinetics; Myocardium; Phenylephrine; Piperazines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sarcolemma; Sodium-Hydrogen Exchangers; Tetrahydronaphthalenes	1998
Characterization, localization and distribution of alpha1 adrenoceptor subtype in male rabbit urethra. The Journal of urology, 1998, Volume: 160, Issue:1 Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Autoradiography; Dioxanes; Immunohistochemistry; Male; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Spiperone; Urethra	1998
Discrimination of alpha1-adrenoceptor subtypes in rat aorta and prostate. Pharmacology, 1998, Volume: 57, Issue:2 Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vasoconstriction; Vasodilator Agents	1998
Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors. FEBS letters, 1999, Jan-29, Volume: 443, Issue:3 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection	1999
Binding and functional characterization of alpha1-adrenoceptor subtypes in the rat prostate. European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1 Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Prostate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tritium	1999
Functional characterization of alpha1-adrenergic receptors in experimental vein grafts. The Journal of surgical research, 1999, Jun-01, Volume: 84, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Carotid Artery, Common; Dioxanes; GTP-Binding Proteins; Jugular Veins; Male; Osmolar Concentration; Pertussis Toxin; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction; Virulence Factors, Bordetella	1999
Characterisation of alpha1B-adrenoceptors linked to inositol phosphate formation and calcium mobilisation in human astrocytoma U373 MG cells. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:5 Topics: Adrenergic alpha-Antagonists; Astrocytoma; Calcium; Cell Membrane; Clonidine; Dihydropyridines; Dioxanes; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Thymidine; Tumor Cells, Cultured	1999
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature. European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine	2000
Alpha(1)-adrenoceptor subtypes mediating contractions of the rat mesenteric artery. European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Indoles; Indoramin; Male; Mesenteric Arteries; Methoxamine; Oxathiins; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents	2000
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries. European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction	2001
Characterization of alpha1-adrenoceptor-mediated contraction in the mouse thoracic aorta. European journal of pharmacology, 2001, Jul-20, Volume: 424, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Buspirone; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Male; Methoxamine; Mice; Models, Biological; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Statistics as Topic; Vasoconstriction	2001
alpha(1)-Adrenoceptor subtypes in the mouse mesenteric artery and abdominal aorta. British journal of pharmacology, 2001, Volume: 134, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Abdominal; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesenteric Arteries; Mice; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction	2001
Pharmacological characterization of alpha1-adrenoceptor subtypes in the bovine tail artery. Journal of veterinary pharmacology and therapeutics, 2002, Volume: 25, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Cattle; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Tail; Tetrahydronaphthalenes; Vasoconstriction	2002
Pharmacological characterization of alpha1-adrenoceptor in mouse iliac artery. European journal of pharmacology, 2002, Dec-05, Volume: 456, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Iliac Artery; In Vitro Techniques; Male; Mice; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction	2002
Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats. European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Mydriasis; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Pupil; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Yohimbine	2003
Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro. Molecular human reproduction, 2003, Volume: 9, Issue:8 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Muscle Relaxation; Myometrium; Piperazines; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Serotonin; Serotonin Antagonists; Uterine Contraction	2003
Different roles of alpha1-adrenoceptor subtypes in mediating cardiomyocyte protein synthesis in neonatal rats. Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:9 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Cell Enlargement; Cells, Cultured; Dioxanes; Indoles; Leucine; Muscle Proteins; Myocytes, Cardiac; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1	2004
Alpha1A-adrenergic receptors are functionally expressed by a subpopulation of cornu ammonis 1 interneurons in rat hippocampus. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; In Vitro Techniques; Interneurons; Isoproterenol; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1	2007
The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism. Molecular pharmacology, 2008, Volume: 74, Issue:4 Topics: Acetophenones; Adrenergic alpha-1 Receptor Antagonists; Anthracenes; Aorta; Apoptosis; Benzothiazoles; Cells, Cultured; Culture Media, Serum-Free; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitochondria; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Pyridines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Time Factors; Toluene; Tumor Suppressor Protein p53	2008
Molecular and pharmacological characteristics of the gerbil α(1a)-adrenergic receptor. Hearing research, 2012, Volume: 283, Issue:1-2 Topics: Adrenergic alpha-1 Receptor Antagonists; Amino Acid Sequence; Animals; Arteries; Chlorocebus aethiops; Clonidine; Cloning, Molecular; Cochlea; Conserved Sequence; COS Cells; Dioxanes; Dose-Response Relationship, Drug; Gerbillinae; Humans; Mice; Molecular Sequence Data; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Sequence Analysis, Protein; Transfection; Vasoconstriction	2012