Compounds > 5-methylurapidil

Page last updated: 2024-08-16

5-methylurapidil and spiperone

5-methylurapidil has been researched along with spiperone in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (78.57)	18.2507
2000's	3 (21.43)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bondinell, WE; Hieble, JP; Ruffolo, RR	1
Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R	1
Pedretti, A; Testa, B; Villa, L; Vistoli, G	1
Kojima, C; Satoh, M; Takayanagi, I	1
Gillis, RA; Kellar, KJ; Mandal, AK	1
Singer, EA; Valenta, B	1
Guarneri, L; Leonardi, A; Poggesi, E; Simonazzi, I; Taddei, C; Testa, R	1
Docherty, JR; Kearns, S; O'Rourke, M	1
Aghajanian, GK; Marek, GJ	1
Kadavil, EA; Oriowo, MA; Yousif, M	1
Foster, HE; Latifpour, J; Nishi, K; Saito, M; Weiss, RM; Yoshida, M	1
Amobi, N; Coker, C; Guillebaud, J; Mulvin, D; Smith, IC	1
Berkowitz, DE; Booth, JV; Cozart, KL; D'Amico, EB; El-Moalem, H; Funk, BL; Marucci, L; Page, SO; Richardson, CD; Rudner, XL; Schwinn, DA; Winters, B	1
Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K	1

Reviews

1 review(s) available for 5-methylurapidil and spiperone

Article	Year
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1995

Other Studies

13 other study(ies) available for 5-methylurapidil and spiperone

Article	Year
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes. Japanese journal of pharmacology, 2001, Volume: 86, Issue:2 Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists	2001
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents	2005
Characterization of alpha 1-adrenoceptor subtypes labeled by [3H]prazosin in single cells prepared from rabbit thoracic aorta. European journal of pharmacology, 1992, Oct-06, Volume: 221, Issue:1 Topics: Animals; Aorta, Thoracic; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Methoxamine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spiperone	1992
The role of serotonin-1A receptor activation and alpha-1 adrenoceptor blockade in the hypotensive effect of 5-methyl-urapidil. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2 Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Hypotension; Injections, Intravenous; Male; Medulla Oblongata; Microinjections; Piperazines; Receptors, Serotonin; Spiperone	1991
Hypotensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin and 5-methylurapidil following stereotaxic microinjection into the ventral medulla of the rat. British journal of pharmacology, 1990, Volume: 99, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxanes; Dopamine Antagonists; Heart Rate; Male; Medulla Oblongata; Microinjections; Naphthalenes; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Spiperone; Spiro Compounds; Stereotaxic Techniques; Tetrahydronaphthalenes	1990
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype. British journal of pharmacology, 1995, Volume: 114, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Computer Simulation; Hippocampus; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regression Analysis; Spiperone; Stereoisomerism; Sulfonamides	1995
Investigation of the actions of chloroethylclonidine in rat aorta. British journal of pharmacology, 1995, Volume: 115, Issue:8 Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine	1995
Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons. European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3 Topics: Action Potentials; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxanes; In Vitro Techniques; Interneurons; Male; Norepinephrine; Oxathiins; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Risperidone; Spiperone	1996
Heterogeneity of alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contractions of the rat superior mesenteric artery. Pharmacology, 1998, Volume: 56, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spiperone; Vasoconstriction; Vasoconstrictor Agents	1998
Characterization, localization and distribution of alpha1 adrenoceptor subtype in male rabbit urethra. The Journal of urology, 1998, Volume: 160, Issue:1 Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Autoradiography; Dioxanes; Immunohistochemistry; Male; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Spiperone; Urethra	1998
Functional characterization of alpha1-adrenoceptor subtypes in longitudinal and circular muscle of human vas deferens. European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Alkylating Agents; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Piperazines; Prazosin; Receptors, Adrenergic; Spiperone; Vas Deferens	1999
Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age. Circulation, 1999, Dec-07, Volume: 100, Issue:23 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aging; Aorta; Arteries; Celiac Artery; Dopamine Antagonists; Female; Femoral Artery; Gene Expression; Hepatic Artery; Humans; Iliac Artery; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Phenylephrine; Piperazines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1; Renal Artery; RNA, Messenger; Saphenous Vein; Spiperone; Splenic Artery; Vasoconstriction	1999
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature. European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine	2000