Page last updated: 2024-08-24

5-methylcytosine and oligonucleotides

5-methylcytosine has been researched along with oligonucleotides in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19907 (13.73)18.7374
1990's6 (11.76)18.2507
2000's12 (23.53)29.6817
2010's22 (43.14)24.3611
2020's4 (7.84)2.80

Authors

AuthorsStudies
Strobl, JS; Thompson, EB1
Sneider, TW1
Adam, S; Conti, M; Huynh-Dinh, T; Igolen, J; Langlois d'Estaintot, B; Neumann, JM; Taboury, JA; Taillandier, E; Tran-Dinh, S1
Bird, AP1
Fujii, S; Rich, A; van Boom, JH; van der Marel, G; Wang, AH1
Sung, WL1
Duhamel-Maestracci, N; Harbers, K; Spencer, JH1
Efremova, EIu; Limborskaia, SA; Miasnikov, VA; Potapov, VK; Prosniak, MI; Sverdlov, ED; Veselovskaia, SI1
Hutchison, CA; Tollefsbol, TO1
Capaldi, DC; Cassidy, SA; Fox, KR; Neidle, S; Reese, CB; Roselt, PD; Slickers, P; Trent, JO1
Boiteux, S; Cadet, J; D'Ham, C; Girard, PM1
Mathison, BH; Ross, MK; Said, B; Shank, RC1
Boudou, V; Busson, R; De Bouvere, B; Herdewijn, P; Kerremans, L; Lescrinier, E; Schepers, G; Van Aerschot, A1
Giege, R; Petyuk, V; Potapov, V; Serikov, R; Tolstikov, V; Vlassov, V; Zenkova, M1
Cernilogar, F; Evangelista, M; Lombardi, L; Miarelli, C; Pitto, L; Rocchi, P1
Amin, S; Colgate, KC; Geacintov, NE; Huang, X; Kolbanovskiy, A1
Iwai, S; O'Connor, TR; Pfeifer, GP; Yoon, JH1
Larivière, L; Moréra, S1
Grange, T; Kress, C; Thomassin, H1
Bradley, K; Capaldi, DC; Cedillo, I; Gaus, H; Kurata, C; Luu, N; McArdle, JV; Ravikumar, VT; Van Sooy, K1
Kamei, T; Okamoto, A; Tainaka, K; Tanaka, K1
Nishimoto, S; Tanabe, K; Yamada, H1
Burden, AF; Genereux, DP; Johnson, WC; Laird, CD; Stöger, R1
Hari, Y; Imanishi, T; Kodama, T; Mitsuoka, Y; Obika, S; Ohnishi, R1
Glick, J; Lin, Y; Noronha, AM; Vouros, P; Wilds, CJ; Xiong, W1
Jin, SG; Kadam, S; Pfeifer, GP1
Kumar, TS; Madsen, AS; Wengel, J1
Hanaoka, F; Iwai, S; Manabe, K; Masutani, C; Nishiguchi, K; Yamamoto, J1
Babu, BR; Hrdlicka, PJ; Maity, J; Wengel, J; Østergaard, ME1
Clark, E; Huang, S; Mulcahey, M; Shi, YG; Zhang, H; Zhang, X1
Ikeda, S; Okamoto, A; Sugizaki, K; Yanagisawa, H1
Dai, Q; He, C1
Hari, Y; Imanishi, T; Kodama, T; Obika, S1
Carell, T; Deiml, CA; Gnerlich, FA; Karaghiosoff, K; Koch, SC; Lischke, U; Münzel, M; Pfaffeneder, T; Stathis, D1
Song, Z; Zhang, Q1
Bitinaite, J; Chin, HG; Corrêa, IR; Dai, N; Pradhan, S1
Pettitt, BM; Sowers, LC; Theruvathu, JA; Yin, YW1
Brown, T; Gerrard, SR; Johannsen, MW; Melvin, T1
Brown, T; Fox, KR; Kimber, ST1
Wang, M; Wong, J; Xiong, J; Xu, RM; Yang, N; Zhou, T; Zhu, B1
Banerjee, S; Brooks, S; Egli, M; Eichman, BF; Joachimiak, A; Nocek, B; Pallan, PS; Stone, MP; Szulik, MW; Voehler, M1
Cui, L; Shao, F; Wu, Q; Xuan, S; Zhang, D1
Han, D; He, C; Jiang, X; Liu, M; Lu, X; Sun, Z; Xia, B; Xie, W; Yi, C; Yin, Q; Zeng, H; Zhou, A1
DeNizio, JE; Kohli, RM; Liu, MY1
Hall, AR; He, C; Zahid, OK; Zhao, BS1
Ennifar, E; Lusser, A; Micura, R; Riml, C1
Fujisaka, A; Hari, Y; Imanishi, T; Obika, S; Pang, J; Rahman, SMA; Takuma, H; Yoshikawa, H1
Gibas, P; Gordevičius, J; Klimašauskas, S; Kriukienė, E; Narmontė, M; Staševskij, Z1
Hunault, L; Saleh, L; Vaisvila, R1
Chakrapani, A; Hocek, M; Krásný, L; Pohl, R; Ruiz-Larrabeiti, O; Vaňková Hausnerová, V1
Jia, TZ; Li, W; Ni, W; Shi, S; Wang, X; Yoo, B; Yuan, X; Zhang, N; Zhang, S1

Other Studies

51 other study(ies) available for 5-methylcytosine and oligonucleotides

ArticleYear
Methylation of either cytosine in the recognition sequence CGCG inhibits ThaI cleavage of DNA.
    Nucleic acids research, 1984, Nov-12, Volume: 12, Issue:21

    Topics: 5-Methylcytosine; Adenoma; Animals; Azacitidine; Base Sequence; Cell Line; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Pituitary Neoplasms; Rats; Substrate Specificity

1984
The 5'-cytosine in CCGG1 is methylated in two eukaryotic DNAs and Msp I is sensitive to methylation at this site.
    Nucleic acids research, 1980, Sep-11, Volume: 8, Issue:17

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cytosine; Deoxyribonucleases; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Liver; Liver Neoplasms, Experimental; Oligodeoxyribonucleotides; Oligonucleotides; Rats

1980
The B----Z transition in two synthetic oligonucleotides: d(C-2-amino-ACGTG) and d(m5CGCAm5CGTGCG) studied by IR, NMR and CD spectroscopies.
    Nucleic acids research, 1984, Aug-10, Volume: 12, Issue:15

    Topics: 5-Methylcytosine; Base Sequence; Circular Dichroism; Cytosine; Deoxyadenosines; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Spectrophotometry, Infrared; Structure-Activity Relationship

1984
DNA methylation versus gene expression.
    Journal of embryology and experimental morphology, 1984, Volume: 83 Suppl

    Topics: 5-Methylcytosine; Animals; Cytosine; Dinucleoside Phosphates; DNA; DNA Replication; DNA, Ribosomal; Gene Expression Regulation; Genes; Methylation; Oligonucleotides; Transcription, Genetic; Xenopus laevis

1984
Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA.
    Nucleic acids research, 1982, Dec-11, Volume: 10, Issue:23

    Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; X-Ray Diffraction

1982
Synthesis of 4-triazolopyrimidinone nucleotide and its application in synthesis of 5-methylcytosine-containing oligodeoxyribonucleotides.
    Nucleic acids research, 1981, Nov-25, Volume: 9, Issue:22

    Topics: 5-Methylcytosine; Cytosine; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Phosphorylation; Pyrimidinones; Triazoles

1981
5-Methylcytosine in the highly repetitive DNA's of the guinea pig (Cavia porcellus).
    Advances in enzyme regulation, 1980, Volume: 19

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA, Satellite; Guinea Pigs; Oligonucleotides; Pyrimidine Nucleotides

1980
[Intensification of genomic dactyloscopy by means of hybridization with modified oligonucleotides, forming duplexes with increased stability].
    Bioorganicheskaia khimiia, 1993, Volume: 19, Issue:9

    Topics: 2-Aminopurine; 5-Methylcytosine; Cytosine; DNA Fingerprinting; Nucleic Acid Hybridization; Oligonucleotides

1993
Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.
    Journal of molecular biology, 1997, Jun-20, Volume: 269, Issue:4

    Topics: 5-Methylcytosine; Animals; Base Sequence; Binding Sites; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; DNA, Single-Stranded; Kinetics; Methyltransferases; Mice; Molecular Sequence Data; Oligonucleotides; Recombinant Proteins

1997
Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine.
    Nucleic acids research, 1997, Dec-15, Volume: 25, Issue:24

    Topics: 5-Methylcytosine; Aminopyridines; Base Composition; Cytosine; DNA Footprinting; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Polydeoxyribonucleotides; Substrate Specificity

1997
Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae.
    Carcinogenesis, 1998, Volume: 19, Issue:7

    Topics: 5-Methylcytosine; Adenine; Bacterial Proteins; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Fungal Proteins; Humans; N-Glycosyl Hydrolases; Oligonucleotides; Purines; Pyridines; Saccharomyces cerevisiae

1998
5-Methylcytosine in CpG sites and the reactivity of nearest neighboring guanines toward the carcinogen aflatoxin B1-8,9-epoxide.
    Biochemical and biophysical research communications, 1999, Jan-08, Volume: 254, Issue:1

    Topics: 5-Methylcytosine; Aflatoxin B1; Carcinogens; Cytosine; Gene Expression Regulation, Neoplastic; Genes, p53; Guanine; Humans; Oligonucleotides

1999
Base pairing of anhydrohexitol nucleosides with 2,6-diaminopurine, 5-methylcytosine and uracil asbase moiety.
    Nucleic acids research, 1999, Mar-15, Volume: 27, Issue:6

    Topics: 2-Aminopurine; 5-Methylcytosine; Arabinonucleosides; Base Pairing; Cytosine; Models, Molecular; Nucleic Acid Denaturation; Nucleosides; Oligonucleotides; Purine Nucleosides; Pyrimidine Nucleosides; Sugar Alcohols; Uracil

1999
Invasion of strongly binding oligonucleotides into tRNA structure.
    Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:7

    Topics: 2-Aminopurine; 5-Methylcytosine; Cytosine; Deoxyuridine; Electrophoresis, Polyacrylamide Gel; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; RNA, Transfer, Phe; Time Factors; Yeasts

2000
Characterization of carrot nuclear proteins that exhibit specific binding affinity towards conventional and non-conventional DNA methylation.
    Plant molecular biology, 2000, Volume: 44, Issue:5

    Topics: 5-Methylcytosine; Binding, Competitive; Cell Differentiation; Cell Division; Cytosine; Daucus carota; DNA Methylation; DNA-Binding Proteins; DNA, Plant; Molecular Weight; Nuclear Proteins; Oligonucleotides; Plant Proteins; Protein Binding

2000
Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context.
    Chemical research in toxicology, 2002, Volume: 15, Issue:3

    Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; Electrophoretic Mobility Shift Assay; Fluorescence; Hot Temperature; Methylation; Molecular Conformation; Oligonucleotides; Stereoisomerism

2002
Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.
    Nucleic acids research, 2003, Sep-15, Volume: 31, Issue:18

    Topics: 5-Methylcytosine; Base Pair Mismatch; Deamination; DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Guanine; Humans; Models, Genetic; Mutation; Oligonucleotides; Recombinant Proteins; Substrate Specificity; Thymine; Thymine DNA Glycosylase

2003
Structural evidence of a passive base-flipping mechanism for beta-glucosyltransferase.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: 5-Methylcytosine; Adenine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cytosine; DNA; Glucosyltransferases; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Protein Binding; Protein Conformation; Uridine Diphosphate

2004
MethylQuant: a sensitive method for quantifying methylation of specific cytosines within the genome.
    Nucleic acids research, 2004, Dec-02, Volume: 32, Issue:21

    Topics: 5-Methylcytosine; Animals; Benzothiazoles; Cell Line, Tumor; CpG Islands; Diamines; DNA Methylation; DNA Primers; DNA, Neoplasm; Fluorescent Dyes; Genomics; Oligonucleotides; Oligonucleotides, Antisense; Organic Chemicals; Polymerase Chain Reaction; Quinolines; Rats; Sequence Analysis, DNA; Sulfites

2004
Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Deoxyadenosines; Molecular Structure; Molecular Weight; Oligonucleotides; Organophosphorus Compounds; Spectrophotometry, Ultraviolet; Thionucleotides

2006
Direct labeling of 5-methylcytosine and its applications.
    Journal of the American Chemical Society, 2007, May-02, Volume: 129, Issue:17

    Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Electrochemistry; Electrodes; Genes, p53; Gold; Indicators and Reagents; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutation; Oligonucleotides; Osmium Compounds; Oxidation-Reduction; Pyridines; Spectrometry, Fluorescence

2007
Fluorometric identification of 5-methylcytosine modification in DNA: combination of photosensitized oxidation and invasive cleavage.
    Bioconjugate chemistry, 2008, Volume: 19, Issue:1

    Topics: 5-Methylcytosine; Base Sequence; DNA Cleavage; DNA Methylation; Flap Endonucleases; Fluorometry; Humans; Oligonucleotides; Oxidation-Reduction; Photochemistry; Temperature; Vitamin K 3

2008
Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies.
    Nucleic acids research, 2008, Volume: 36, Issue:22

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA, Single-Stranded; Nucleic Acid Conformation; Oligonucleotides; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Temperature

2008
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
    Nucleic acids research, 2009, Volume: 37, Issue:4

    Topics: 5-Methylcytosine; Adenine; Base Pair Mismatch; Bridged-Ring Compounds; Circular Dichroism; DNA; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acids; Oligonucleotides; RNA; Thymine

2009
The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:8

    Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analytic Sample Preparation Methods; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Codon; Cytosine; DNA; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Humans; Microchemistry; Mutagens; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine.
    Nucleic acids research, 2010, Volume: 38, Issue:11

    Topics: 5-Methylcytosine; Antibodies; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Immunoprecipitation; Oligonucleotides; Sequence Analysis, DNA; Sulfites

2010
LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis.
    Organic & biomolecular chemistry, 2010, Nov-07, Volume: 8, Issue:21

    Topics: 5-Methylcytosine; Candida; Fungal Proteins; Lipase; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Stereoisomerism; Thymine

2010
Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer.
    Nucleic acids research, 2011, Volume: 39, Issue:3

    Topics: 5-Methylcytosine; DNA-Directed DNA Polymerase; Humans; Hydrogen-Ion Concentration; Hydrolysis; Oligonucleotides; Organophosphorus Compounds; Photochemical Processes; Pyrimidine Dimers; Stereoisomerism; Temperature; Thymine; Ultraviolet Rays

2011
Novel insights into the use of Glowing LNA as nucleic acid detection probes--influence of labeling density and nucleobases.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: 5-Methylcytosine; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleic Acid Probes; Oligonucleotides; Pyrenes; Quantum Theory; Spectrometry, Fluorescence; Thymine; Transition Temperature

2010
TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine.
    Cell research, 2010, Volume: 20, Issue:12

    Topics: 5-Methylcytosine; DNA Methylation; DNA-Binding Proteins; Humans; Hydroxylation; Mixed Function Oxygenases; Oligonucleotides; Protein Structure, Tertiary; Proto-Oncogene Proteins; Transcription, Genetic

2010
Facile synthesis of hydroxymethylcytosine-containing oligonucleotides and their reactivity upon osmium oxidation.
    Organic & biomolecular chemistry, 2011, Jun-07, Volume: 9, Issue:11

    Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; Models, Molecular; Molecular Structure; Oligonucleotides; Osmium; Oxidation-Reduction; Stereoisomerism; Transition Temperature

2011
Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.
    Organic letters, 2011, Jul-01, Volume: 13, Issue:13

    Topics: 5-Methylcytosine; Cytosine; Deoxycytidine; DNA; Methylation; Molecular Structure; Oligonucleotides; Oxidation-Reduction

2011
2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 764

    Topics: 5-Methylcytosine; Adenine; Biological Products; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Cytosine; DNA; Guanine; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA; Thymine

2011
Improved synthesis and mutagenicity of oligonucleotides containing 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Dec-02, Volume: 17, Issue:49

    Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; Molecular Structure; Mutagens; Oligonucleotides; Organophosphorus Compounds; Spectrometry, Mass, Electrospray Ionization

2011
Design, synthesis, and incorporation of fluorous 5-methylcytosines into oligonucleotides.
    The Journal of organic chemistry, 2011, Dec-16, Volume: 76, Issue:24

    Topics: 5-Methylcytosine; Catalysis; Chemistry Techniques, Synthetic; Chromatography, Liquid; DNA; DNA Methylation; Fluorine; Halogenation; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Probes; Octamer Transcription Factor-3; Oligonucleotides; Palladium; Promoter Regions, Genetic; Silicon Dioxide; Solid Phase Extraction

2011
Evaluation of UDP-GlcN derivatives for selective labeling of 5-(hydroxymethyl)cytosine.
    Chembiochem : a European journal of chemical biology, 2013, Nov-04, Volume: 14, Issue:16

    Topics: 5-Methylcytosine; Animals; Antibodies; Bacteriophage T4; Cytosine; DNA; Embryonic Stem Cells; Fluorescent Dyes; Glucosamine; Glucosyltransferases; Glycosylation; Mice; Oligonucleotides; Staining and Labeling; Substrate Specificity; Uracil Nucleotides

2013
Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence.
    Biochemistry, 2013, Nov-26, Volume: 52, Issue:47

    Topics: 5-Methylcytosine; Cytosine; Hot Temperature; Hydrogen Bonding; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; X-Ray Diffraction

2013
Triplex-mediated analysis of cytosine methylation at CpA sites in DNA.
    Chemical communications (Cambridge, England), 2014, Jan-18, Volume: 50, Issue:5

    Topics: 5-Methylcytosine; CpG Islands; DNA; DNA Methylation; Hydrogen-Ion Concentration; Nucleic Acid Hybridization; Oligonucleotides; Transition Temperature

2014
A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: 5-Methylcytosine; Bacterial Proteins; Base Sequence; Cytosine; DNA; Escherichia coli; Gene Expression; Molecular Sequence Data; Mutation; Oligonucleotides; Recombinant Proteins; Substrate Specificity; Thymine; Uracil; Uracil-DNA Glycosidase

2014
Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2.
    Molecular cell, 2014, Jun-05, Volume: 54, Issue:5

    Topics: 5-Methylcytosine; Binding Sites; Crystallography, X-Ray; Cytosine; Humans; Hydrogen Bonding; Models, Molecular; Oligonucleotides; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Ubiquitin-Protein Ligases

2014
Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
    Biochemistry, 2015, Feb-10, Volume: 54, Issue:5

    Topics: 5-Methylcytosine; Cytosine; DNA; Oligonucleotides; Thymine DNA Glycosylase

2015
5-Hydroxymethylcytosine and 5-formylcytosine containing deoxyoligonucleotides: facile syntheses and melting temperature studies.
    Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6

    Topics: 5-Methylcytosine; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Copper; Cytosine; Oligonucleotides; Oxidation-Reduction; Transition Temperature

2015
Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
    Nature methods, 2015, Volume: 12, Issue:11

    Topics: 5-Methylcytosine; Animals; Cell Line; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Epigenomics; Gene Expression Regulation; Genome; Mice; Mice, Transgenic; Oligonucleotides; Oxygen; Polymerase Chain Reaction; Sequence Analysis, DNA; Stem Cells; Sulfites

2015
Quantification of Oxidized 5-Methylcytosine Bases and TET Enzyme Activity.
    Methods in enzymology, 2016, Volume: 573

    Topics: 5-Methylcytosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Enzyme Assays; Humans; Immunoblotting; Insecta; Mixed Function Oxygenases; Nucleosides; Oligonucleotides; Oxidation-Reduction; Proto-Oncogene Proteins; Recombinant Proteins; Tandem Mass Spectrometry

2016
Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores.
    Scientific reports, 2016, 07-07, Volume: 6

    Topics: 5-Methylcytosine; Animals; Biotinylation; DNA; Epigenesis, Genetic; Genomics; Mice; Nanopores; Oligonucleotides; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Ultrasonics

2016
Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
    The Journal of organic chemistry, 2017, 08-04, Volume: 82, Issue:15

    Topics: 5-Methylcytosine; Carbohydrate Conformation; Crystallography, X-Ray; Models, Molecular; Oligonucleotides; RNA; Thermodynamics

2017
Effective syntheses of 2',4'-BNA
    Bioorganic & medicinal chemistry, 2019, 04-15, Volume: 27, Issue:8

    Topics: 5-Methylcytosine; Adenine; Bridged-Ring Compounds; Glycosylation; Guanine; Nucleotides; Oligonucleotides; Thymine; Transition Temperature; Ultraviolet Rays

2019
Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing.
    PLoS biology, 2020, Volume: 18, Issue:4

    Topics: 5-Methylcytosine; Acetylation; Animals; Bacteriophage lambda; Cell Line; DNA Methylation; Embryonic Stem Cells; Genome; Histones; Lysine; Mice; Oligonucleotides; Reproducibility of Results; Sequence Analysis, DNA; Sulfites

2020
Detection of TET-Oxidized 5-Methylcytosine Bases by Capillary Gel Electrophoresis.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2198

    Topics: 5-Methylcytosine; Data Analysis; Electrophoresis, Capillary; Enzyme Activation; Humans; Mixed Function Oxygenases; Oligonucleotides; Oxidation-Reduction

2021
Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labeling of DNA.
    Organic letters, 2020, 11-20, Volume: 22, Issue:22

    Topics: 5-Methylcytosine; Deoxycytidine; DNA; Epigenesis, Genetic; Epigenomics; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Pyrimidine Nucleosides; Uracil; Uridine

2020
A General LC-MS-Based Method for Direct and De Novo Sequencing of RNA Mixtures Containing both Canonical and Modified Nucleotides.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2298

    Topics: 5-Methylcytosine; Chromatography, Liquid; Hydrophobic and Hydrophilic Interactions; Nucleotides; Oligonucleotides; Pseudouridine; RNA; RNA Processing, Post-Transcriptional; Sequence Analysis, RNA; Tandem Mass Spectrometry; Uridine

2021