5-methylcytosine has been researched along with cytosine in 1409 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 315 (22.36) | 18.7374 |
| 1990's | 272 (19.30) | 18.2507 |
| 2000's | 118 (8.37) | 29.6817 |
| 2010's | 624 (44.29) | 24.3611 |
| 2020's | 80 (5.68) | 2.80 |
| Authors | Studies |
|---|---|
| Hayatsu, H; Shiragami, M | 1 |
| Lesyng, B; Saenger, W | 1 |
| Childs, JD; Gentner, NE; Paterson, MC; Smith, BP | 1 |
| Cambell, JL; Fleischman, RA; Richardson, CC | 1 |
| Khomov, IS; Tikhonenko, TI | 1 |
| Ebright, RH; Ebright, YW; Gunasekera, A | 1 |
| Matsuda, M; Yasutomi, M | 1 |
| Creighton, S; Goodman, MF; Jones, PA; Shen, JC | 1 |
| Hofsteenge, J; Jost, JP | 1 |
| Celewicz, L; Shetlar, MD | 1 |
| Bernardi, G; Gehrke, CW; Kuo, KC; Macaya, G; Matassi, G; Melis, R | 1 |
| Hagerman, PJ; Hodges-Garcia, Y | 1 |
| Collis, CM; Frommer, M; Grigg, GW; McDonald, LE; Millar, DS; Molloy, PL; Paul, CL; Watt, F | 1 |
| Jones, PA; Rideout, WM; Shen, JC; Spruck, CH; Tsai, YC | 1 |
| Bhagwat, AS; McClelland, M | 1 |
| Capel, J; Filipski, J; Gil, P; Martínez-Zapater, JM; Montero, LM; Salinas, J | 1 |
| Crowther, PJ; Doherty, JP; Krüger, DH; Linsenmeyer, ME; Woodcock, DM | 1 |
| Gomez-Eichelmann, MC; Levy-Mustri, A; Ramirez-Santos, J | 1 |
| Gartler, SM; Hansen, RS | 1 |
| Comb, M; Goodman, HM | 1 |
| Coetzee, GA; Jones, PA; Olumi, AF; Rideout, WM | 1 |
| Cosgrove, DE; Cox, GS | 1 |
| Bona, R; Cozzi, R; D'Erme, M; Palitti, F; Perticone, P | 1 |
| Storch, TG | 1 |
| Goodman, M; Miller, DA; Tagle, DA | 1 |
| Catravas, GN; Kalinich, JF; Snyder, SL | 2 |
| Ratner, DI; Smith, SS | 1 |
| Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N | 1 |
| Vilpo, JA; Vilpo, LM | 3 |
| Nyce, J | 2 |
| Drouin, G | 1 |
| Boublik, M; Ofengand, J; Tumminia, SJ; Weitzmann, C | 1 |
| Bednarik, DP; Duckett, C; Folks, TM; Griffis, K; Guenthner, PC; Kim, SU; Perez, VL | 1 |
| Camerino, G; Goodfellow, P | 1 |
| Lieb, M | 2 |
| Kelleher, JE; Raleigh, EA | 1 |
| Aresta, AM; Kanduc, D; Prisco, M; Rossiello, MR | 1 |
| Coetzee, GA; Jones, PA; Olumi, AF; Rideout, WM; Spruck, CH | 1 |
| Golenser, J; Kogan, N; Pollack, Y | 1 |
| Bird, A; Lewis, J | 1 |
| Garro, AJ; Lieber, CS; Lima, V; McBeth, DL | 1 |
| Bourbonnière, M; Nalbantoglu, J | 1 |
| Corvetta, A; Della Bitta, R; Luchetti, MM; Pomponio, G | 1 |
| Bründl, K; Fritz, HJ; Hennecke, F; Kolmar, H | 1 |
| Manzini, G; Quadrifoglio, F; van Boom, JH; van der Marel, GA; Xodo, LE | 1 |
| Misawa, S; Ueda, S; Washio, K | 1 |
| Baker, DJ; Dembek, P; Kan, JL; Kaplan, BE; Smith, SS | 1 |
| Perutz, MF | 1 |
| Crain, PF | 1 |
| Ehrlich, M; Inamdar, NM; Zhang, XY | 1 |
| Ho, PS; Zhou, GW | 1 |
| Dehmel, A; Doerfler, W; Kochanek, S; Renz, D; Toth, M | 1 |
| Bolden, A; Ward, C; Weissbach, A | 1 |
| Reddy, PM; Reddy, PR | 2 |
| Baskova, IP; Nikonov, GI; Romanenko, EB; Vaniushin, BF | 1 |
| Craig, AG; Hoheisel, JD; Lehrach, H | 1 |
| Ghosh, SS; Gingeras, TR; Kwoh, TJ; Obermiller, PS | 1 |
| Adouard, V; Dante, R; Delain, E; Ehrlich, M; Niveleau, A; Revet, B | 1 |
| Selker, EU; Stevens, JN | 1 |
| Baev, AA; Bogdarina, IG; Bur'ianov, IaI; Zinkevich, VE | 1 |
| Jones, PA; Kautiainen, TL | 1 |
| Haaf, T; Ott, G; Scheres, JM; Schmid, M; Wensing, JA | 1 |
| Everett, CA; Finch, M; Hart, IR; Ormerod, EJ | 1 |
| Holliday, R | 3 |
| Fairweather, DS; Fox, M; Margison, GP | 1 |
| Gunter, KC; Sneller, MC | 1 |
| Hirai, K; Ikuta, K; Kanamori, A; Kato, S; Ueda, S | 1 |
| Davie, JR; Delcuve, GP | 2 |
| Nahon, JL; Sala-Trepat, JM; Tratner, I; Venetianer, A | 1 |
| Babin, F; Bloch, G; Huynh-Dinh, T; Neumann, JM | 1 |
| Bedford, MT; van Helden, PD | 1 |
| Heuertz, S; Homman, N; Hors-Cayla, MC | 1 |
| Jones, PA; Michalowsky, LA | 2 |
| Veselý, J | 1 |
| Isham, KR; Kenney, FT; Lee, KL; Rothrock, R | 1 |
| Fioretti, MC; Fuschiotti, P; Puccetti, P; Romani, L | 1 |
| Antequera, F; Bird, AP; Macleod, D | 1 |
| Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R | 1 |
| Farooq, M; Holliday, R; Hunter, JL; Matsumura, T | 1 |
| Coble, DW; Lyon, SB; Veres, DA; Wilkins, L | 1 |
| Chandler, LA; Jones, PA | 1 |
| Piekarowicz, A; Stein, DC; Yuan, R | 1 |
| Doerfler, W; Lichtenberg, U; Toth, M | 1 |
| Cox, R; Kuykendall, JR | 1 |
| Dervan, PB; Maher, LJ; Wold, B | 1 |
| Korba, BE; Wilson, VL; Yoakum, GH | 1 |
| Atsumi, G; Bessho, T; Harada, Y; Hayatsu, H; Negishi, K; Negishi, T | 1 |
| Achberger, EC; Braymer, HD; Ross, TK | 1 |
| Fehér, Z; Hattman, S; Miner, Z; Schlagman, SL | 2 |
| Jost, JP; Saluz, H | 1 |
| Tisdale, MJ | 2 |
| Adams, RL; So, CL | 1 |
| Ehrlich, KC; Ehrlich, M; Supakar, PC; Zhang, DL | 1 |
| Del Senno, L; Hanau, S; Maestri, I; Piva, R; Reggiani, A; Romano, A; Russo, G | 1 |
| Shaw, AA; Shetlar, MD | 1 |
| Annan, RS; Giese, RW; Kresbach, GM; Vouros, P | 1 |
| Bird, AP; Kleiner, EL; Lewis, JD; McKay, S; Meehan, RR | 1 |
| Aarbakke, J; Loennechen, T; Prytz, PS | 1 |
| Boorstein, RJ; Chiu, LN; Teebor, GW | 1 |
| Mueller, PR; Pfeifer, GP; Riggs, AD; Steigerwald, SD; Wold, B | 1 |
| Butkus, V; Janulaitis, A; Klimasauskas, S; Laucys, V; Maneliene, Z; Petrauskiene, L | 1 |
| Maniloff, J; Sladek, TL | 1 |
| Andrews, PA; Ehrlich, M; Gehrke, CW; Loflin, PT; Zhang, XY | 1 |
| Bou, M; Hoshina, M; Mochizuki, M | 1 |
| Blumenthal, RM; Elhai, J; Hanahan, D; Murray, NE; Raleigh, EA; Reith, AD; Revel, H; Rigby, PW; Westaway, D | 1 |
| Coene, MM; Hoet, PP; Hottat, FG; Padhy, RN | 1 |
| Molloy, PL; Watt, F | 1 |
| Labbé, S; Roy, PH; Xia, YN | 1 |
| Imokawa, M; Sager, R; Sano, H | 1 |
| Fisher, DH; Giese, RW | 1 |
| Jäger, K; Potts, M | 1 |
| Grahn, H; Grätz, R; Kröger, H; Wohlert, H | 1 |
| Bianchi, NO; Cleaver, JE; Vidal-Rioja, L | 1 |
| Ehrlich, KC; Ehrlich, M; Inamdar, N; Khan, R; Supakar, PC; Weist, D; Zhang, DL; Zhang, XY | 1 |
| Blake, TJ; Drinkwater, RD; Morley, AA; Turner, DR | 1 |
| Imanishi, K; Maie, O; Sano, H; Shiomi, N; Shiomi, T | 1 |
| Adams, RL; Lindsay, S; Monk, M | 1 |
| McCloskey, JA; Rachlin, EM; Rodland, KD; Russell, PJ | 1 |
| Jones, M; Radman, M; Wagner, R | 1 |
| Gopinathan, KP; Patel, CV | 1 |
| Ehrlich, M; Feinstein, SI; Gehrke, CW; Miller, DA; Miller, OJ; Racaniello, VR | 1 |
| Cook, PR; Dyson, PJ; Searle, S; Wyke, JA | 1 |
| Guha, S | 1 |
| Hardman, N; Pearston, D; Peoples, OP; Whittaker, PA | 1 |
| Butkus, V; Janulaitis, A; Kersulyte, D; Klimasauskas, S; Lebionka, A; Vaitkevicius, D | 1 |
| Butkus, VV; Janulaitis, AA; Klimasauskas, SJ | 1 |
| Antequera, F; Santos, T; Tamame, M; Vilanueva, JR | 1 |
| Hare, JT; Taylor, JH | 1 |
| Ab, G; Gruber, M; Philipsen, JN | 1 |
| Kerbel, RS; Liteplo, RG | 2 |
| Maniloff, J; Nowak, JA; Sladek, TL | 1 |
| Cech, D; Kusnezova, SA; Orezkaja, TS; Rosenthal, A; Schubert, F; Shabarova, ZA | 1 |
| Jupe, ER; Magill, CW; Magill, JM | 1 |
| Ehrlich, M; Wang, RY; Zhang, XY | 1 |
| Chandler, VL; Walbot, V | 1 |
| Raleigh, EA; Wilson, G | 1 |
| Hagblom, P; Korch, C | 1 |
| Ono, A; Ueda, T | 1 |
| Braymer, HD; Ross, TK | 1 |
| Breznik, T; Butel, JS; Cohen, JC; Gama-Sosa, MA; Medina, D | 1 |
| Wilson, VG | 1 |
| Heitman, J; Model, P | 1 |
| Fritz, HJ; Zell, R | 1 |
| Fritzsche, E; Hayatsu, H; Igloi, GL; Iida, S; Kössel, H | 1 |
| Butkus, V; Janulaitis, A; Klimasauskas, S; Lebionka, A; Maneliene, Z; Petrauskiene, L | 1 |
| Brown, TC; Jiricny, J | 1 |
| MacNeil, DJ | 1 |
| Agostini, S; Cantoni, GL; Kafri, T; Levine, A; Razin, A | 1 |
| Crowther, PJ; Diver, WP; Jefferson, S; Woodcock, DM | 1 |
| Pósfai, G; Szybalski, W | 1 |
| Günthert, U; Reiners, L | 1 |
| Bailey, G; Davie, JR; Delcuve, GP; Moirier, R; Nickel, BE | 1 |
| Bethel, P; Dorwin, EL; Hom, K; Shaw, AA; Sheltar, MD | 1 |
| Li, D; Lu, LJ; Randerath, K | 1 |
| Attinà, M; Cacace, F; Caiafa, P; Mastrantonio, S; Rispoli, M; Strom, R | 1 |
| Distefano, S; Ekpenyong, K; Hom, K; Shetlar, MD; Yang, J | 1 |
| Lobanenkov, VV | 1 |
| Kirnos, MD; Vanyushin, BF | 1 |
| Caserta, M; Larson, JE; O'Connor, TR; Wells, RD; Zacharias, W | 1 |
| Harrington, MA; Imagawa, M; Jones, PA; Karin, M | 1 |
| Benvenisty, N; Reshef, L | 1 |
| Blumenthal, RM | 1 |
| Cooper, DN; Youssoufian, H | 1 |
| Ehrlich, M; Feinberg, AP; Gehrke, CW; Kuo, KC | 1 |
| Bolt, HM; Jäger, R; Peter, H; Sterzel, W | 1 |
| Cannon, SV; Cummings, A; Teebor, GW | 1 |
| Boehm, TL; Drahovsky, D; Pfeifer, GP; Steigerwald, S | 1 |
| Barna, T; Becker, FF; Holton, P; Lapeyre, JN; Malinowski, J; Ruchirawat, M | 1 |
| Butkus, VV; Ianulaĭtis, AA; Iurgaĭtis, AP; Klimashauskas, SI | 1 |
| Galazka, G; Klysik, J; Kwinkowski, M; Okruszek, A; Uznanski, B; Zacharias, W | 1 |
| Ivanova, ZI; Kliasheva, RI; Vasil'ev, ZhKh | 1 |
| Catania, J; Fairweather, DS; Keenan, BC; Margison, GP | 1 |
| Cantoni, GL; Carotti, D; Giloh, H; Kafri, T; Razin, A; Roll, M; Scarpa, S; Szyf, M | 1 |
| Jiricny, J; Jost, JP; Saluz, HP | 1 |
| Buonocore, L; Lyon, SB; Miller, M | 1 |
| Ehrlich, M; Gehrke, CW; Kuo, KC; Norris, KF; Wang, RY | 1 |
| Avanzi, S; Durante, M; Frediani, M; Tagliasacchi, AM | 1 |
| Murray, V | 1 |
| Frederick, CA; Rich, A; Saal, D; van Boom, JH; van der Marel, GA; Wang, AH | 1 |
| Vaniushin, BF; Zhavoronkova, EN | 1 |
| Granoff, A; Thompson, JP; Willis, DB | 1 |
| Butkus, V; Janulaitis, A; Klimasauskas, S; Maneliene, Z; Minchenkova, LE; Petrauskiene, L; Schyolkina, AK | 1 |
| Meyerowitz, EM; Pruitt, RE | 1 |
| Attină, M; Cacace, F; Caiafa, P; Strom, R; Tomassetti, A | 1 |
| Hammen, RF; Johnson, TE; Simpson, VJ | 1 |
| Torsten, U | 1 |
| Pukkila, PJ; Zolan, ME | 1 |
| Barbin, A; Bartsch, H; Friesen, M; O'Neill, I | 1 |
| Bickle, TA; Bogdarina, IG; Buryanov, YI; Krüger, DH; Reuter, M; Schroeder, C | 1 |
| Kaczmarek, L; Surmacz, E | 1 |
| Beck, DC; Clouse, JA; Howell, BA; Kizer, DE; Ringer, DP | 1 |
| Hagblom, P; Korch, C; Normark, S | 1 |
| Rasi, S; Suvanto, E; Vilpo, JA; Vilpo, LM | 1 |
| Autrup, H; Harris, CC; Krokan, H; Le, NN; Longoria, J; Musci, DE; Smith, RA; Wilson, VL; Ziska, D | 1 |
| Carreira, LH; Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Ljungdahl, LG | 1 |
| Kolata, G | 1 |
| Eremenko, T; Morelli, F; Palitti, F; Volpe, P; Whitehead, EP | 1 |
| Goldstein, S; Shmookler Reis, RJ | 1 |
| Ikushima, T | 1 |
| Jones, PA; Wilson, VL | 2 |
| Bestor, TH; Hellewell, SB; Ingram, VM | 1 |
| Erickson, RP; Ferrucci, S; Morello, D; Rahe, B; Rosenberg, MP | 1 |
| Erlanger, BF; Guntaka, RV; Miller, OJ; Tantravahi, U | 1 |
| Eastman, EM; Erlanger, BE; Goodman, R; Miller, OJ; Wei, LH | 1 |
| Desrosiers, RC | 1 |
| Maharajan, V; Pratibha, M; Scarano, E; Tosi, L | 1 |
| Bird, S; Cowing, D; Gusella, J; Hoffmann, JW; Steffen, D; Tabin, C; Weinberg, RA | 1 |
| Adams, RL; Burdon, RH | 1 |
| Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM | 1 |
| Harris, JS; Lu, LJ; Randerath, K; Tseng, WC | 1 |
| Jekunen, A; Puukka, M; Vilpo, J | 1 |
| Jones, PA; Momparler, RL; Wilson, VL | 1 |
| Lu, LJ; Randerath, E; Randerath, K | 1 |
| Cooper, DN | 1 |
| Jones, PA; Riggs, AD | 1 |
| Barker, D; Schafer, M; White, R | 1 |
| Jones, PA; Taylor, SM; Wilson, V | 1 |
| Constantinides, PA; Jones, PA; Taylor, SM | 1 |
| Christman, JK | 1 |
| Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA | 1 |
| Strobl, JS; Thompson, EB | 1 |
| Citti, L; Durante, M; Nobili, R; Salvini, M | 1 |
| Baev, AA; Bogdarina, IG; Bur'ianov, IaI | 1 |
| Achwal, CW; Chandra, HS; Ganguly, P | 1 |
| Cohen, JC | 1 |
| Guntaka, RV; Katz, R; Mitsialis, SA; Rao, PY | 1 |
| Coca-Prados, M; Ford, JP; Hsu, MT | 1 |
| Ehrlich, M; Farber, MB | 1 |
| Royer, HD; Sager, R; Sano, H | 1 |
| Bird, AP | 4 |
| Sneider, TW | 1 |
| Granoff, A; Willis, DB | 1 |
| Ehrlich, M; Wang, RY | 1 |
| Cedar, H; Gruenbaum, Y; Naveh-Many, T; Razin, A | 1 |
| Schwartz, SA | 1 |
| Sturm, KS; Taylor, JH | 1 |
| Coalson, DW; Diala, ES; Hoffman, RM; Plent, MM | 1 |
| Doerfler, W | 2 |
| Krebs, A; Spencer, JH | 1 |
| Diala, ES; Hoffman, RM | 3 |
| Hjelle, BL; Phillips, JA; Seeburg, PH | 1 |
| Dybvig, K; Hattman, S; Maniloff, J; Swinton, D | 1 |
| Hays, JB; Korba, BE | 1 |
| Baur, R; Kluge, N; Kröger, H; Wohlert, H | 1 |
| Clough, W; Larocca, D | 1 |
| Benade, LE; Drohan, WN; Graham, DE; Smith, GH | 1 |
| Kunnath, L; Locker, J | 1 |
| Doering, JL; Hoyle, HD; Sims, MA | 1 |
| Doerfler, W; Renz, D; Vardimon, L | 1 |
| Clayton, RM; Cooper, DN; Errington, LH | 1 |
| Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Oxenhandler, R; Slagel, VA; Trewyn, RW | 1 |
| Johnstone, AP; Williams, GT | 1 |
| Adelman, J; Comb, M; Herbert, E; Rosen, H; Seeburg, P | 1 |
| Macdonald, PM; Mosig, G | 1 |
| Ehrlich, M; Shenoy, S; Wang, RY | 1 |
| Antequera, F; Santos, T; Tamame, M; Villanueva, JR | 1 |
| Kasir, J; Metzger, S; Pollack, Y; Shemer, R; Szyf, M | 1 |
| Breznik, T; Butel, JS; Cohen, JC; Ehrlich, M; Gama-Sosa, M; Gehrke, CW; Medina, D; Traina-Dorge, V | 1 |
| Adam, S; Conti, M; Huynh-Dinh, T; Igolen, J; Langlois d'Estaintot, B; Neumann, JM; Taboury, JA; Taillandier, E; Tran-Dinh, S | 1 |
| Childs, JD; Ellison, MJ; Pilon, R | 1 |
| Nishioka, Y; Vasilikaki-Baker, H | 1 |
| Magee, PN; Nyce, J; Weinhouse, S | 1 |
| Radman, M; Wagner, R | 1 |
| Vanyushin, BF | 1 |
| Davie, JR; Hattman, S; Proffitt, JH; Swinton, D | 1 |
| Achwal, CW; Chandra, HS; Iyer, CA | 1 |
| Doerfler, W; Eick, D; Fritz, HJ | 1 |
| Mazin, AL; Mukhovatova, LM; Shuppe, NG; Vaniushin, BF | 1 |
| Goldberg, EB; Levy, JN | 1 |
| Pearson, RE; Snyder, L | 1 |
| Cedar, H; Gruenbaum, Y; Pollack, Y; Razin, A; Stein, R | 1 |
| Cavaillès, JA; Garnier, A; Hervé, M; Huynh-Dinh, T; Igolen, J; Langlois d'Estaintot, B; Neumann, JM; Tran-Dinh, S | 1 |
| Latimer, LJ; Lee, JS; Morgan, AR; Woodsworth, ML | 1 |
| Flodin, NW | 1 |
| Mezquita, C; Rocamora, N | 1 |
| Kliasheva, RI; Vasil'ev, ZhK | 1 |
| Nur, I; Razin, S; Rottem, S | 1 |
| Giese, RW; Hayes, MJ; Mohamed, GB; Nazareth, A; Vouros, P | 1 |
| Giese, RW; Nazareth, A; O'Connell, K; Sentissi, A | 1 |
| Deutsch, WA; Green, DA | 1 |
| Randolph, VA; Reboulleau, CP; Shapiro, HS; Williams, J | 1 |
| Ball, DJ; Garrard, WT; Gross, DS | 1 |
| Cheah, MS; Diala, ES; Hoffman, RM; Rowitch, D | 1 |
| Aujame, L; Craig, J; McBurney, MW | 1 |
| Crain, PF; McCloskey, JA | 1 |
| Kliasheva, RI | 2 |
| Bondy, GP; Denhardt, DT | 1 |
| Debov, SS; Földes, I; Nikolskaya, II; Somogyi, PA | 1 |
| Bagshaw, JC; Warner, AH | 1 |
| Hattman, S; Nur, U; Scarbrough, K | 1 |
| Bur'ianov, IaI; Venozhinskis, MT | 1 |
| Erlanger, BF; Fang, JS; Jagiello, G; Tantravahi, U | 1 |
| Erlanger, BF; Miller, DA; Miller, OJ; Okamoto, E | 2 |
| Bur'ianov, IaI; Kanopkaĭte, SI; Venozhinskis, MT | 1 |
| Follmann, H; Theiss, G | 1 |
| Eastman, EM; Erlanger, BF; Goodman, RM; Miller, OJ | 1 |
| Ammermann, D; Baur, R; Steinbrück, G; Wohlert, H | 1 |
| Gopinathan, KP; Ramakrishnan, T; Srivastava, R | 1 |
| Koshland, ME; Yagi, M | 1 |
| Rogers, J; Wall, R | 1 |
| Burtseva, NN; Gimadutdinov, OA; Romanov, GA; Vaniushin, BF | 1 |
| Pegg, AE | 1 |
| Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Wang, RY | 1 |
| Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Githens, S; Kuo, KC; Midgett, RM; Slagel, VA | 1 |
| Grahn, H; Kröger, H; Wohlert, H | 1 |
| Citti, L; Durante, M; Gervasi, PG; Mariani, L; Turchi, G | 1 |
| Bogenmann, E; Flatau, E; Jones, PA | 1 |
| Busslinger, M; Flavell, RA; Hurst, J | 1 |
| Cedar, H; Doerfler, W; Kuhlmann, I; Vardimon, L | 1 |
| Haigh, LS; Hellewell, S; Ingram, VM; Owens, BB; Roninson, IB | 1 |
| Cedar, H; Naveh-Many, T | 1 |
| Arutiunian, SG; Danielian, IS; Garibian, V; Stephanian, GM | 1 |
| Harbers, K; Jaenisch, R; Jähner, D; Schnieke, A; Stuhlmann, H | 1 |
| Cedar, H; Razin, A; Stein, R | 1 |
| Sager, R; Sano, H | 1 |
| Cedar, H; Quint, A | 1 |
| Boehm, TL; Drahovsky, D | 1 |
| Warren, RA | 1 |
| Romanov, GA; Vaniushin, BF | 1 |
| Sano, H | 1 |
| Ehrlich, M; Gama-Sosa, MA; Gehrke, C; Huang, LH; Kuo, KC; McCune, RA; Midgett, RM | 1 |
| Chow, TY; Kuo, TT; Lin, YT | 1 |
| Ehrlich, M; Gehrke, CW; Huang, LH; Kuo, KC; Wang, RY | 1 |
| Nishio, A; Uyeki, EM | 1 |
| Meerson, FZ; Vasil'ev, VK | 1 |
| Fujii, S; Rich, A; van Boom, JH; van der Marel, G; Wang, AH | 1 |
| Földes, I; Maso Bel, M; Somogyi, PA | 1 |
| Wigler, MH | 1 |
| Adams, JK; Cooper, IA; Woodcock, DM | 1 |
| Romanov, GA; Vanyushin, BF | 1 |
| Capesius, I; Wagner, I | 1 |
| Aleksandrushkina, NI; Kirnos, MD; Vaniushin, BF | 1 |
| Dashkevich, VS; Dudareva, NA; Kuz'menko, AP; Salganik, RI | 1 |
| Eden, FC; Musti, AM; Sobieski, DA | 1 |
| Sung, WL | 1 |
| Duhamel-Maestracci, N; Harbers, K; Spencer, JH | 1 |
| Alexandrushkina, NI; Demidkina, NP; Kirnos, MD; Kiryanov, GI; Vanyushin, BF | 1 |
| Kornacka, L; Malec, J; Sawecka, J | 1 |
| Kliasheva, RI; Panfilova, GA; Volkov, VE | 1 |
| Razin, A; Razin, S | 1 |
| Kulińska, K; Psoda, A; Shugar, D | 1 |
| Eremenko, T; Timofeeva, MY; Volpe, P | 1 |
| Briggs, RS; Day, IN; Ganderton, RH | 1 |
| Meyer, P | 1 |
| Selker, EU; Singer, MJ | 1 |
| Faugeron, G; Rossignol, JL | 1 |
| Ford, BN; Glickman, BW; Skandalis, A | 1 |
| Claeys, KM; Foss, HM; Roberts, CJ; Selker, EU | 1 |
| Cupples, CG; Passi, E; Petropoulos, L; Vidmar, JJ | 1 |
| Graessmann, A; Graessmann, M; Guhl, E; Sandberg, G | 1 |
| LeBon, JM; Riggs, AD; Singer-Sam, J; Tommasi, S | 1 |
| Hsieh, CL | 1 |
| Duker, NJ; Vairapandi, M | 2 |
| Lavrushina, O; Lukiw, WJ; Rogaev, EI; Rogaeva, EA; St George-Hyslop, PH | 1 |
| Campos, A; Fernández, JL; Gosálvez, J; Goyanes, V; Pereira, S | 1 |
| Kreider, JW; Lang, CM; Peng, X | 1 |
| Ahmed, M; Esumi, M; Kato, T | 1 |
| Mangues, R; Pellicer, A; Schwartz, S; Seidman, I | 1 |
| Bhagwat, AS; Yebra, MJ | 1 |
| Little, M; Wainwright, B | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Balansky, R; De Flora, S; Giannoni, P; Izzotti, A; Novikov, L | 1 |
| Gromova, ES; Oretskaya, TS; Petrauskene, OV; Romanova, EA; Shabarova, ZA; Volkov, EM | 1 |
| Kato, I; Ohshima, A; Sagawa, H | 1 |
| Clark, SJ; Frommer, M; Harrison, J | 1 |
| Boorstein, RJ; Teebor, GW; Zuo, S | 1 |
| Grigg, GW; Holliday, R | 1 |
| Deutsch, JC; Kolhouse, JF | 1 |
| Chalasani, S; Dy, L; Essani, K | 1 |
| Rogers, JC; Rogers, SW | 1 |
| el Antri, S; Fermandjian, S; Lefebvre, A; Lescot, E; Mauffret, O; Monnot, M | 1 |
| Aksamit, RR; Cantoni, GL; Kasir, J; Merta, A | 1 |
| Martin, CC; McGowan, R | 1 |
| Bandaru, B; Bhagwat, AS; Wyszynski, M | 1 |
| Klimasauskas, S; Roberts, RJ | 1 |
| Steinberg, RA | 1 |
| Jost, JP; Raizis, AM; Schmitt, F | 1 |
| Engler, P; Storb, U; Weng, A | 2 |
| Gold, JD; Pedersen, RA | 1 |
| Begley, CG; Doig, RG; McGrath, KM | 1 |
| Castro, GD; Castro, JA; Stamato, CJ | 1 |
| Blanquet, V; Bonneau, D; Fischer, A; Herbelin, C; Jeanpierre, M; Miniou, P; Niveleau, A; Sibella, V; Viegas-Péquignot, E | 1 |
| Kuff, EL; Lueders, KK | 1 |
| Gannett, P; Gold, B; Liang, G | 1 |
| Cadet, J; Douki, T | 1 |
| Efremova, EJ; Limborska, SA; Myasnikov, VA; Potapov, VK; Prosnyak, MI; Sverdlov, ED; Veselovskaya, SI | 1 |
| Barbin, A; Bourgeois, CA; Dutrillaux, B; Gibaud, A; Kokalj-Vokac, N; Malfoy, B; Montpellier, C; Niveleau, A | 1 |
| Jones, PA; Rideout, WM; Schmutte, C; Shen, JC | 1 |
| Counts, JL; Goodman, JI | 2 |
| Christophe, D; Pichon, B | 1 |
| Adams, EF; Buchfelder, M; Fahlbusch, R; Hüttner, A | 1 |
| Coetzee, GA; Eversole-Cire, P; Gonzales, FA; Hustad, CM; Jones, PA; Rideout, WM; Spruck, CH | 1 |
| Clark, SJ; Frommer, M; Harrison, J; Paul, CL | 1 |
| Jasem, P; Tóthová, J | 1 |
| Ariel, M; Cedar, H; McCarrey, J | 1 |
| Hong, H; Janosi, L; Kaji, A; Yonemitsu, H | 1 |
| Clark, S; Grigg, G | 1 |
| Aurias, A; Fischer, A; Jeanpierre, M; Ledeist, F; Prieur, M; Turleau, C; Viegas-Pequignot, E | 1 |
| Botfield, MC; Weiss, MA | 1 |
| Mathews, CK; Zhang, X | 1 |
| Bird, AP; Charlton, J; Feil, R; Reik, W; Walter, J | 1 |
| Cohen, SS | 1 |
| Jones, PA; Rideout, WM; Shen, JC | 1 |
| Prydz, H; Reeben, M | 1 |
| Kaeppler, SM; Olhoft, P; Phillips, RL | 1 |
| Alunni-Fabbroni, M; Manzini, G; Xodo, LE | 1 |
| Griffin, S; Karran, P | 1 |
| Ehrlich, KC | 2 |
| Efremova, EIu; Limborskaia, SA; Miasnikov, VA; Potapov, VK; Prosniak, MI; Sverdlov, ED; Veselovskaia, SI | 1 |
| Beachy, TM; Millard, JT | 1 |
| Fritz, DY; Selker, EU; Singer, MJ | 1 |
| Bird, AP; Meehan, RR; Ulrich, E | 1 |
| Hornstra, IK; Nelson, DL; Warren, ST; Yang, TP | 1 |
| Bentivegna, SS; Bresnick, E | 1 |
| Jaishree, TN; Wang, AH | 1 |
| Hornstra, IK; Yang, TP | 1 |
| Verdine, GL | 1 |
| Cheng, X; Klimasauskas, S; Kumar, S; Roberts, RJ | 1 |
| Hennig, UG; von Borstel, RC | 1 |
| Black, DM; Gilham, PT | 1 |
| Kakutani, T; Martienssen, RA; Richards, EJ; Vongs, A | 1 |
| Gatewood, JM; Hellmann-Blumberg, U; Hintz, MF; Schmid, CW | 1 |
| Burkhart, JG; Malling, HV | 1 |
| Cupples, CG; Létourneau, S; Ruiz, SM | 1 |
| Butler, RH; Eremenko, T; Iacovacci, P; Volpe, P | 1 |
| Bednarik, DP | 1 |
| Hughes, M; Jiricny, J; Neddermann, P; Wiebauer, K | 1 |
| Doherty, JP; Williamson, MR; Woodcock, DM | 1 |
| Leonard, SA; Nyce, JW; Wong, SC | 1 |
| Weissbach, A | 1 |
| Zacharias, W | 1 |
| Jones, PA; Rideout, WM; Spruck, CH | 1 |
| Mathison, BH; Said, B; Shank, RC | 1 |
| Nelson, PS; Papas, TS; Schweinfest, CW | 1 |
| Aoike, A; Fujita, T; Ohtani-Fujita, N; Osifchin, NE; Robbins, PD; Sakai, T | 1 |
| Liu, WM; Schmid, CW | 1 |
| Kawakubo, K; Ohyashiki, JH; Ohyashiki, K; Shimamoto, T; Tauchi, T; Toyama, K | 1 |
| Bird, AP; Tate, PH | 1 |
| Barry, C; Faugeron, G; Rossignol, JL | 1 |
| Jost, JP | 1 |
| McClelland, M; Que, Q; Ralph, D; Van Etten, JL | 1 |
| Futscher, BW; Watts, GS | 1 |
| Ramakrishnan, B; Sundaralingam, M | 1 |
| Bernardino, J; Bourgeois, CA; Dutrillaux, B; Gibaud, A; Malfoy, B; Niveleau, A; Veilleux, C | 1 |
| Hemavathy, KC; Nagaraja, V | 1 |
| Beck, R; Metzler, M; Pechan, R; Pfeiffer, E; Schuler, M; Slany, M | 1 |
| Brooks, PJ; Goldman, D; Marietta, C | 1 |
| Harris, CC | 1 |
| Castro, GD; Castro, JA; Díaz Gómez, MI | 1 |
| Heinlein, M; Kunze, R; Wang, L | 1 |
| Bernardino, J; Bourgeois, CA; Dutrillaux, B; Lamoliatte, E; Lombard, M; Malfoy, B; Niveleau, A | 1 |
| Burnett, AK; Ramsahoye, BH; Taylor, C | 1 |
| Heby, O | 1 |
| Jeddeloh, JA; Richards, EJ | 1 |
| Jones, PA | 1 |
| Chen, J; Dellaporta, SL; Galbiati, M; Ronemus, MJ; Ticknor, C | 1 |
| Corsten, S; Hohn, T; Müller, M; Rieke, S; Rothnie, H | 1 |
| Dennis, ES; Finnegan, EJ; Peacock, WJ | 1 |
| Venitt, S | 1 |
| Akopyants, N; Azhikina, T; Berg, D; Lebedev, Y; Potapov, V; Shevchenko, Y; Stecenko, D; Sverdlov, E | 1 |
| Castiglione, MR; Frediani, M; Giraldi, E | 1 |
| Bukowska, AM; Kuśmierek, JT | 1 |
| de Capoa, A; Di Leandro, M; Giancotti, P; Grappelli, C; Marotta, MR; Menendez, F; Niveleau, A; Poggesi, I; Reynaud, C | 1 |
| Privat, E; Sowers, LC | 1 |
| Bloom, LB; Day, RS; Gallinari, P; Goodman, MF; Jiricny, J; Xu, YZ | 1 |
| Ambinder, RF; Gulley, ML; Manns, A; Robertson, KD; Swinnen, LJ; Zong, JC | 1 |
| Fritz, HJ; Horst, JP | 1 |
| Bestor, TH; Ghibu, F; Li, E; Trasler, DG; Trasler, JM | 1 |
| Grigg, GW | 1 |
| Bozzi, A; Carotti, D; Cianfriglia, M; Lucarelli, M; Palitti, F; Signoretti, C; Strom, R | 1 |
| DePamphilis, ML; Rein, T; Zorbas, H | 2 |
| Eskelinen, M; Hakkarainen, M; Hiltunen, MO; Jänne, J; Johansson, R; Myöhänen, S; Wahlfors, J | 1 |
| Fujimoto, J; Lin, SS; Sowers, LC; Tardy-Planechaud, S | 1 |
| Lieb, M; Rehmat, S | 1 |
| Gonzalgo, ML; Jones, PA | 2 |
| Wachsman, JT | 1 |
| Buiting, K; Dittrich, B; Doerfler, W; Horsthemke, B; Schmitz, B; Zeschnigk, M | 1 |
| Magill, C; Magill, JM; Newton, RJ; Zhou, Y | 1 |
| Sundaralingam, M; Tippin, DB | 1 |
| Depicker, A; Montagu, MV | 1 |
| Jones, PA; Zingg, JM | 1 |
| Laird, PW | 1 |
| Hutchison, CA; Tollefsbol, TO | 1 |
| Bhagwat, AS; Khariwala, SS; Sheluho, D; Yebra, MJ | 1 |
| Counts, JL; Goodman, JI; Kaznowski, JM; McClain, RM | 1 |
| Holmquist, GP; Pfeifer, GP | 1 |
| Allain, P; Boisdron-Celle, M; Gamelin, E; Larra, F; Robert, J; Turcant, A | 1 |
| Jost, JP; Oakeley, EJ; Podestà, A | 1 |
| Ganesh, KN; Jadhav, VR; Rajeev, KG | 1 |
| Clark, SJ; Melki, JR; Millar, DS; Paul, CL; Stirzaker, C; Warnecke, PM | 1 |
| Denissenko, MF; Pfeifer, GP; Tommasi, S | 1 |
| Dulieu, H; Gianinazzi-Pearson, V; Hosny, M; Païs de Barros, JP | 1 |
| Krüger, DH; Kupper, D; Meisel, A; Reuter, M | 1 |
| Capaldi, DC; Cassidy, SA; Fox, KR; Neidle, S; Reese, CB; Roselt, PD; Slickers, P; Trent, JO | 1 |
| Dedon, PC; Mathur, P; Xu, J | 1 |
| Bestor, TH; Xu, GL | 1 |
| Jones, PA; Robertson, KD | 2 |
| Bestor, TH; Yoder, JA | 1 |
| Bird, A | 2 |
| Hirono, H; Kito, H; Komatsu, K; Shoji, Y; Suzuki, T; Suzuki, Y; Takada, G; Takahashi, T; Yokoyama, T | 1 |
| Archidiacono, N; de Capoa, A; Di Leandro, M; Giancotti, P; Grappelli, C; Marotta, MR; Menendez, F; Niveleau, A; Poggesi, I; Rocchi, M; Spanò, A | 1 |
| Christiansen-Weber, T; Haas, M; Haggblom, C; Vogt, M; Yeargin, J | 1 |
| Choo, Y | 1 |
| Bailly, C; Carrasco, C; Waring, MJ | 1 |
| Mayer-Jung, C; Moras, D; Timsit, Y | 1 |
| Denissenko, MF; Pfeifer, GP | 1 |
| Bensaada, M; Cacheux, V; Kiefer, H; Lapierre, JM; Métézeau, P; Niveleau, A; Tachdjian, G | 1 |
| Bourc'his, D; Gomes, DM; Niveleau, A; Pàldi, A; Plachot, M; Rougier, N; Viegas-Péquignot, E | 1 |
| Boiteux, S; Cadet, J; D'Ham, C; Girard, PM | 1 |
| Buzek, J; Ebert, I; Greilhuber, J; Ruffini-Castiglione, M; Siroký, J; Vyskot, B | 1 |
| Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL | 1 |
| Ge, R; Kramer, PM; Pereira, MA; Tao, L | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| Bezdek, M; Fulnecek, J; Kovarík, A; Matyásek, R | 1 |
| Finette, BA; O'Neill, JP | 1 |
| Davey, MW; Grigg, GW; Paulin, R; Piper, AA | 1 |
| Futscher, BW; Massey-Brown, KS; Rice, JC | 1 |
| Clark, SJ; Harrison, J; Stirzaker, C | 1 |
| Côté, S; Momparler, RL; Sinnett, D | 1 |
| Caiafa, P; de Capoa, A; Febbo, FR; Giovannelli, F; Marenzi, S; Niveleau, A; Zardo, G | 1 |
| Bakin, AV; Curran, T | 1 |
| Mathison, BH; Ross, MK; Said, B; Shank, RC | 1 |
| Almeida Toledo-Filho, S; Almeida-Toledo, LF; Coutinho-Barbosa, AC; Foresti, F; Niveleau, A; Viegas-Péquignot, E | 1 |
| Blumenthal, RM; Koons, MD; Rice, MR | 1 |
| Bernardi, G; Jabbari, K | 2 |
| Michel, H; Nurse, K; Ofengand, J; Popienick, P; Sochacki, M; Tscherne, JS | 1 |
| Dubeau, L; Ehrlich, M; Narayan, A; Qu, G; Yu, MC | 1 |
| Genda, Y; Nagane, Y; Tohgi, H; Ukitsu, M; Utsugisawa, K; Yoshimura, M | 2 |
| Boudou, V; Busson, R; De Bouvere, B; Herdewijn, P; Kerremans, L; Lescrinier, E; Schepers, G; Van Aerschot, A | 1 |
| Arnaud, P; Deragon, JM; Goubely, C; Heslop-Harrison, JS; Tatout, C | 1 |
| Gu, XR; Gustafsson, C; Ku, J; Santi, DV; Yu, M | 1 |
| Blackman, RL; Devonshire, AL; Field, LM; Tyler-Smith, C | 1 |
| Radlińska, M; Skowronek, K | 1 |
| Piekarowicz, A; Radlińska, M | 1 |
| Bhattacharya, SK; Cervoni, N; Ramchandani, S; Szyf, M | 1 |
| Ahuja, N; Baylin, SB; Ho, C; Issa, JP; Jair, KW; Li, Q; Ohe-Toyota, M; Toyota, M | 1 |
| Klimasauskas, S; Vilkaitis, G | 1 |
| Cupples, CG; Macintyre, G; Pitsikas, P | 1 |
| Bhagwat, AS; Lutsenko, E | 2 |
| Cordier, C; Couesnon, T; Dodin, G; Marcourt, L | 1 |
| Jost, JP; Oakeley, EJ; Schmitt, F | 1 |
| Li, C; Pfeifer, GP; You, YH | 1 |
| Cafolla, A; Cordone, I; de Capoa, A; Febbo, FR; Foa, R; Grappelli, C; Niveleau, A; Spanò, A | 1 |
| Castilho, A; Heslop-Harrison, JS; Neves, N; Rufini-Castiglione, M; Viegas, W | 1 |
| Bur'ianov, IaI; Shevchuk, TV | 1 |
| Grange, T; Oakeley, EJ; Thomassin, H | 1 |
| Shevchenko, OV; Tsebrzhinskiĭ, OI | 1 |
| Abbondandolo, A; Aprile, A; Burns, PA; Campomenosi, P; Fronza, G; Inga, A; Menichini, P; Monti, P; Ottaggio, L; Scott, G; Viaggi, S | 1 |
| Meehan, RR; Stancheva, I | 1 |
| Fundele, R; Haaf, T; Mayer, W; Niveleau, A; Walter, J | 1 |
| Eritja, R; Ferrer, E; Shevchenko, A | 1 |
| Arnaud, P; Deragon, JM; Goubely, C; Pélissier, T | 1 |
| Bickle, TA; Panne, D; Raleigh, EA; Stewart, FJ | 1 |
| Gross, HJ; Jank, P | 1 |
| Baylin, SB; Herman, JG; Jair, KW; Kinzler, KW; Lengauer, C; Rhee, I; Schuebel, KE; Vogelstein, B; Yen, RW | 1 |
| Leitner, D; Schröder, W; Weisz, K | 1 |
| Denissenko, MF; Pfeifer, GP; Tang, M | 1 |
| Bird, A; Hendrich, B | 1 |
| Biniszkiewicz, D; Bird, AP; Clark, V; Jaenisch, R; Lyko, F; Ramsahoye, BH | 1 |
| Pfeifer, GP | 2 |
| Baudrimont, I; Creppy, EE; Dano, SD; Guarigues, P; Narbonne, JF; Ruiz, S; Sanni, A; Traoré, A | 1 |
| Freitag, M; Miao, VP; Selker, EU | 1 |
| Glickman, BW; Stuart, GR | 1 |
| Bates, S; Chin, PL; Dammann, R; Li, C; Pfeifer, GP; Yoon, JH | 1 |
| Ehrlich, M; Fiala, ES; Narayan, A; Sawyer, J; Smeets, DF; Sohn, OS; Tsien, F; Tuck-Muller, CM | 1 |
| Finta, C; Kiss, A; Raskó, T | 1 |
| Futscher, BW; Rice, JC | 1 |
| Chaput, JC; Cox, MM; Rice, KP; Switzer, C | 1 |
| Fryxell, KJ; Zuckerkandl, E | 1 |
| Bujnicki, JM; Radlinska, M; Rychlewski, L | 1 |
| Giege, R; Petyuk, V; Potapov, V; Serikov, R; Tolstikov, V; Vlassov, V; Zenkova, M | 1 |
| Allamane, S; Benabid, AL; Berger, F; Dupré, I; Jourdes, P; Lainé, M; Ratel, D; Vicat, JM; Wion, D | 1 |
| Borniquel, S; Callejas, S; Gutiérrez, JC; Martín-González, A | 1 |
| Fütterer, J; He, X; Hohn, T | 1 |
| Gowher, H; Jeltsch, A; Leismann, O | 1 |
| Frost, AR; Grizzle, WE; Heimburger, DC; Johanning, GL; Manne, U; Niveleau, A; Piyathilake, CJ; Whiteside, MA | 1 |
| Pfeifer, GP; You, YH | 1 |
| Cernilogar, F; Evangelista, M; Lombardi, L; Miarelli, C; Pitto, L; Rocchi, P | 1 |
| Atwood, CV; Cupples, CG; Macintyre, G | 1 |
| Antonarakis, SE; Cooper, DN; Krawczak, M | 1 |
| Babinger, P; Kobl, I; Mages, W; Schmitt, R | 1 |
| Lyko, F | 1 |
| Issa, JP; Kantarjian, HM; Santini, V | 1 |
| Espinás, ML; Flavin, M; Grange, T; Thomassin, H | 1 |
| Costello, JF; Plass, C | 1 |
| Chen, TC; Hsieh, SY; Lee, WC; Liaw, YF; Lin, CH; Sheen, IS; Shyu, WC | 1 |
| Bell, DC; Cupples, CG | 1 |
| Fatemi, M; Hermann, A; Jeltsch, A; Pradhan, S | 1 |
| Ellis, TH; Knox, MR | 1 |
| Clark, SJ; Grunau, C; Rosenthal, A | 1 |
| Carter, KB; Cauthron, RD; Gan, J; Steinberg, RA; Zhang, YL | 1 |
| Bailly, C; Waring, MJ | 1 |
| Bell, WC; Frost, AR; Grizzle, WE; Heimburger, DC; Johanning, GL; Niveleau, A; Oelschlager, D; Piyathilake, CJ; Weiss, H | 1 |
| Bernardino-Sgherri, J; Dutrillaux, B | 1 |
| Ehrlich, KC; Gowher, H; Jeltsch, A | 1 |
| Holt, BJ; Holt, PG; Watt, PM; White, GP | 1 |
| Amin, S; Colgate, KC; Geacintov, NE; Huang, X; Kolbanovskiy, A | 1 |
| Attwood, JT; Richardson, BC; Yung, RL | 1 |
| Bhattacharya, SK; Szyf, M | 1 |
| Dodge, JE; Li, E; Okano, M; Ramsahoye, BH; Wo, ZG | 1 |
| Clark, SJ; Grunau, C; Melki, JR; Song, J; Stirzaker, C; Warnecke, PM | 1 |
| Grønbaek, K; Guldberg, P; Worm, J | 1 |
| Laird, PW; Siegmund, KD | 1 |
| Bird, A; Bishop, SM; Clarke, AR; Guy, J; Hendrich, B; Keightley, PD; MacDougall, E; Millar, CB; Sansom, OJ; Selfridge, J | 1 |
| Avila, S; Capella, G; Esteller, M; Fraga, MF; Herman, JG; Paz, MF; Peinado, MA; Pollan, M; Sanchez-Cespedes, M | 1 |
| Johanning, GL; Piyathilake, CJ | 1 |
| Okamoto, A; Saito, I; Tanabe, K | 1 |
| King, MY; Redman, KL | 1 |
| Esteller, M; Fraga, MF | 1 |
| Harashima, H; Kamiya, H; Karino, N; Matsuda, A; Tsuchiya, H; Ueno, Y | 1 |
| Bertoli, E; Cacciamani, T; Centurelli, M; Eremenko, T; Virgili, S; Volpe, P | 1 |
| Havlis, J; Trbusek, M | 1 |
| Kazianis, S; Li, HY; Obermoeller, RD; Savage, T; Walter, RB | 1 |
| Intano, GW; Kazianis, S; Li, HY; Walter, CA; Walter, RB | 1 |
| Fulnecek, J; Kovarík, A; Matyásek, R | 1 |
| Mathieu, O; Picard, G; Tourmente, S | 1 |
| Abu, M; Waters, TR | 1 |
| Anane, R; Baudrimont, I; Carratú, MR; Creppy, EE; Gbeassor, MF; Mobio, TA; Narbonne, JF; Sanni, A; Shier, TW; Tavan, E | 1 |
| Lee, DH; Pfeifer, GP | 1 |
| Mo, LE; Song, YZ; Zhu, QF; Zhuang, HQ | 1 |
| Law, RD; Suttle, JC | 2 |
| Bartolomei, MS; Bishop, MD; Cezar, GG; Eilertsen, KJ; First, NL; Forsberg, EJ | 1 |
| Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M | 1 |
| Bell, DA; Tomso, DJ | 1 |
| Asmus, F; Gasser, T; Grabowski, M; Kalscheuer, V; Lorenz-Depiereux, B; Meitinger, T; Strom, TM; Zimprich, A | 1 |
| Buterin, T; Colgate, KC; Geacintov, NE; Kolbanovsij, A; Muheim, R; Naegeli, H | 1 |
| Grogan, DW | 1 |
| Hole, EO; Krivokapić, A; Sagstuen, E | 1 |
| CHASE, M; DIXON, J; HERSHEY, AD | 1 |
| COHEN, SS; WYATT, GR | 1 |
| COHEN, SS; WEED, LL | 1 |
| DEVITRY, F | 1 |
| WYATT, GR | 1 |
| Brem, G; Hiendleder, S; Lyko, F; Mund, C; Reichenbach, HD; Wenigerkind, H; Wolf, E; Zakhartchenko, V | 1 |
| Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K | 1 |
| Larivière, L; Moréra, S | 1 |
| Bird, A; Burdzy, A; Rogstad, DK; Sowers, LC; Tsai, HH; Valinluck, V | 1 |
| Butler, JS; Ladd, PD; Skalnik, DG | 1 |
| Dueñas-Gonzalez, A; Revilla Vázquez, A; Sandoval Guerrero, K; Segura-Pacheco, B | 1 |
| Angeles, E; Cabrera, G; Cetina, L; Chanona-Vilchis, J; Chavez-Blanco, A; Duenas-González, A; Perez-Cardenas, E; Revilla-Vazquez, A; Sandoval, K; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C; Zambrano, P | 1 |
| Bart, A; van Amsterdam, K; van der Ende, A; van Passel, MW | 1 |
| Walsh, CP; Xu, GL | 1 |
| Ariza, RR; Martínez-Macías, MI; Morales-Ruiz, T; Ortega-Galisteo, AP; Ponferrada-Marín, MI; Roldán-Arjona, T | 1 |
| Kamei, T; Okamoto, A; Tainaka, K | 1 |
| Okamoto, A; Tainaka, K | 1 |
| Hayatsu, H; Negishi, K; Tsuji, K | 1 |
| Okamoto, A; Tainaka, K; Tanaka, K | 1 |
| Nishimoto, S; Tanabe, K; Yamada, H | 2 |
| Bair, CL; Black, LW | 1 |
| Bair, CL; Black, LW; Rifat, D | 1 |
| Sowers, LC; Valinluck, V | 1 |
| Kamei, T; Okamoto, A; Tainaka, K; Tanaka, K | 1 |
| Hayatsu, H; Moriyama, K; Negishi, K; Shiraishi, M; Tsuji, K | 1 |
| ELION, GB; HITCHINGS, GH | 1 |
| Chen, Z; Cokus, SJ; Feng, S; Haudenschild, CD; Jacobsen, SE; Merriman, B; Nelson, SF; Pellegrini, M; Pradhan, S; Zhang, X | 1 |
| Dziaman, T; Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R; Siomek, A; Szpila, A | 1 |
| Deng, Z; He, X; Li, L; Wu, J; Xu, X; Xu, Z; Zabriskie, TM; Zhang, Y | 1 |
| Simmen, MW | 1 |
| Guza, R; Matter, B; Tretyakova, N | 1 |
| Nakatani, K; Oka, Y; Peng, T; Takei, F | 1 |
| Burden, AF; Genereux, DP; Johnson, WC; Laird, CD; Stöger, R | 1 |
| Hanna, K; Lyko, F; Pollex, T; Schaefer, M | 1 |
| Agarwal, S; Aravind, L; Bandukwala, H; Brudno, Y; Iyer, LM; Koh, KP; Liu, DR; Pastor, WA; Rao, A; Shen, Y; Tahiliani, M | 1 |
| Heintz, N; Kriaucionis, S | 1 |
| Glick, J; Lin, Y; Noronha, AM; Vouros, P; Wilds, CJ; Xiong, W | 1 |
| Bettuzzi, S; Patra, SK | 1 |
| Carambula, SF; Hansen, PJ; Oliveira, LJ | 1 |
| Ito, T; Nishimoto, S; Tanabe, K; Yamada, H | 1 |
| Eisenhardt, C; Krauss, V; Unger, T | 1 |
| Cadet, J; Wagner, JR | 2 |
| Hemberger, M | 1 |
| Huang, Y; Liu, DR; Pastor, WA; Rao, A; Shen, Y; Tahiliani, M | 1 |
| Jin, SG; Kadam, S; Pfeifer, GP | 1 |
| Dunican, D; Meehan, R; Nestor, C; Ruzov, A | 1 |
| Goto, K; Hirono, S; Kato, D; Niwa, O; Sekioka, N; Ueda, A | 1 |
| Biel, M; Brückl, T; Carell, T; Globisch, D; Michalakis, S; Müller, M; Münzel, M; Wagner, M; Welzmiller, V | 1 |
| D'Alessio, AC; Hong, K; Ito, S; Sowers, LC; Taranova, OV; Zhang, Y | 1 |
| Acosta-Silva, C; Bertran, J; Branchadell, V; Oliva, A | 1 |
| Bultmann, S; Leonhardt, H; Schmidt, CS; Spada, F; Szwagierczak, A | 1 |
| Aichinger, E; Köhler, C | 1 |
| Carell, T; Lercher, L; Müller, M; Münzel, M | 1 |
| Bayley, H; Donohoe, TJ; Heron, AJ; Maglia, G; Mikhailova, E; Stoddart, D; Wallace, EV | 1 |
| Larson, GP; Lee, DH; Oates, N; Pfeifer, GP; Rivas, GE; Singh, P; Szabó, PE; Tran, DA | 1 |
| Nakamura, Y; Urata, H; Wada, S; Yamaguchi, E | 1 |
| Carell, T; Globisch, D; Münzel, M; Trindler, C | 1 |
| Chen, CH; Dai, Q; Fu, Y; Godley, LA; He, C; Hicks, LM; Jian, X; Jin, P; Lahn, BT; Li, X; Li, Y; Looney, TJ; Song, CX; Szulwach, KE; Wang, J; Yi, C; Zhang, B; Zhang, L; Zhang, W | 1 |
| Benner, J; Cohen-Karni, D; Drndic, M; Fields, L; Johnson, RR; Klein, ML; Peterman, N; Wanunu, M; Zheng, Y | 1 |
| Biel, M; Brückl, T; Carell, T; Globisch, D; Koch, S; Michalakis, S; Müller, M; Münzel, M; Wagner, M | 1 |
| Frye, S; Guan, KL; Ito, S; Jiang, WQ; Kim, SH; Lei, QY; Liu, J; Liu, LX; Liu, Y; Wang, B; Wang, P; Xiao, MT; Xiong, Y; Xu, W; Xu, YH; Yang, C; Yang, H; Yang, Y; Zhang, JY; Zhang, Y; Zhao, SM | 1 |
| Fan, G; Faull, KF; Kim, KP; Le, T | 1 |
| Cunniff, K; Daley, GQ; Huang, Y; Koh, KP; Lahesmaa, R; Laiho, A; Mostoslavsky, G; Nardone, J; Orkin, SH; Rao, A; Rao, S; Rodig, SJ; Sommer, CA; Tahiliani, M; Yabuuchi, A | 1 |
| Dahl, JA; Klungland, A; Krokan, HE; Robertson, AB; Tripathi, P; Vågbø, CB | 1 |
| Davis, T; Vaisvila, R | 1 |
| Moran, RG; Peterson, EJ; Shock, LS; Taylor, SM; Thakkar, PV | 1 |
| Iqbal, K; Jin, SG; Pfeifer, GP; Szabó, PE | 1 |
| Dahl, C; Grønbæk, K; Guldberg, P | 1 |
| Grigaitytė, I; Klimašauskas, S; Kriukienė, E; Liutkevičiūtė, Z; Masevičius, V | 1 |
| Brachmann, A; Bultmann, S; Leonhardt, H; Schmidt, CS; Spada, F; Szwagierczak, A | 1 |
| Jin, SG; Li, AX; Pfeifer, GP; Wu, X | 1 |
| Arand, J; Boiani, M; Lepikhov, K; Marques, CJ; Nakamura, T; Nakano, T; Reik, W; Walter, J; Wossidlo, M; Zakhartchenko, V | 1 |
| Cui, K; D'Alessio, AC; Ito, S; Sun, YE; Wang, Z; Wu, H; Xia, K; Zhang, Y; Zhao, K | 1 |
| Brown, T; El-Sagheer, AH; Hansen, AS; Schofield, CJ; Thalhammer, A | 1 |
| Cui, K; D'Alessio, AC; Ito, S; Sun, YE; Wang, Z; Wu, H; Zhang, Y; Zhao, K | 1 |
| Andrews, S; Branco, MR; Ficz, G; Hore, TA; Krueger, F; Marques, CJ; Reik, W; Santos, F; Seisenberger, S | 1 |
| Dai, Q; He, C; Pan, T; Song, CX | 1 |
| Höbartner, C | 1 |
| Christensen, J; Cloos, PA; Helin, K; Johansen, JV; Pedersen, MT; Rappsilber, J; Williams, K | 1 |
| Ikeda, S; Okamoto, A; Sugizaki, K; Yanagisawa, H | 1 |
| Barbera, AJ; Chen, T; Deng, J; Huang, S; Kong, L; Min, J; Nicholson, T; Shi, Y; Shi, YG; Tan, L; Wu, F; Xiong, L; Xu, G; Xu, Y; Zhang, H; Zhang, K; Zheng, L | 1 |
| Dai, Q; He, C; Song, CX; Yu, M | 1 |
| He, C; Song, CX | 3 |
| Cowley, MJ; Cropley, JE; Li, CC; Martin, DI; Preiss, T; Suter, CM | 1 |
| Agarwal, S; Brudno, Y; Daley, GQ; Ecker, JR; Henderson, HR; Huang, Y; Kapranov, P; Ko, M; Lister, R; Liu, XS; Mahapatra, S; McLoughlin, EM; Milos, PM; Pape, UJ; Pastor, WA; Rao, A; Tahiliani, M | 1 |
| Peters, AH; Véron, N | 1 |
| Bitinaite, J; Chin, HG; Estève, PO; Feng, S; Jacobsen, SE; Kinney, SM; Pradhan, S; Stroud, H; Vaisvila, R; Zheng, Y | 1 |
| Brenner, C; Chia, N; Lu, X; Ruden, DM; Senut, MC; Wang, L | 1 |
| Bohlander, SK; Bultmann, S; Dufour, A; Herold, T; Kakadia, PM; Konstandin, N; Ksienzyk, B; Leonhardt, H; Mulaw, M; Schneider, F; Schneider, S; Spiekermann, K; Szwagierczak, A | 1 |
| Dai, Q; He, C | 1 |
| Dai, Q; He, C; Lu, XY; Song, CX; Sun, Y; Yang, CG; Yu, M | 1 |
| Carell, T; Globisch, D; Münzel, M | 1 |
| Feng, S; Jacobsen, SE; Morey Kinney, S; Pradhan, S; Stroud, H | 1 |
| Nomura, A; Okamoto, A; Sugizaki, K; Yanagisawa, H | 1 |
| Klungland, A; Robertson, AB; Robertson, J | 1 |
| Carell, T; Deiml, CA; Hackner, B; Hagemeier, C; Müller, M; Münzel, M; Pfaffeneder, T; Truss, M | 1 |
| Abramowitz, LK; Alberti, C; Bartolomei, MS; Bassi, MR; Bellacosa, A; Bruno, T; Caretti, E; Cigliano, A; Cortellino, S; Davidson, I; Devarajan, K; Fanciulli, M; Klein-Szanto, AJ; Kobi, D; Larue, L; Le Coz, M; Matsumoto, Y; Moore, R; Rambow, F; Renner, C; Sannai, M; Soprano, D; Wessels, A; Xu, J | 1 |
| Han, JW; He, C; Hermetz, K; Jin, P; Kim, JJ; Kim, S; Li, X; Li, Y; Namburi, S; Ren, B; Rudd, MK; Song, CX; Szulwach, KE; Yoon, YS | 1 |
| Antes, I; Bultmann, S; Cardoso, MC; Casa, V; Frauer, C; Hoffmann, T; Leonhardt, H | 1 |
| Almire, C; Bernard, OA; Carbonne, B; Casadevall, N; da Costa Reis Monte Mor, B; Delhommeau, F; Droin, N; Godley, LA; Larghero, J; Le Couédic, JP; Massé, A; Mokrani, H; Pendino, F; Plo, I; Pronier, E; Ravanat, JL; Simon, A; Solary, E; Vainchenker, W; Vasanthakumar, A | 1 |
| Bai, Y; Bradley, M; Chandran, S; Chebotareva, T; De Sousa, P; Dudnakova, T; Fletcher, J; Hannoun, Z; Hay, DC; Pells, S; Ruzov, A; Serio, A; Sullivan, G; Tsenkina, Y; Wilmut, I | 1 |
| Hari, Y; Imanishi, T; Kodama, T; Obika, S | 1 |
| Wu, H; Zhang, Y | 3 |
| Collins, LB; Dai, Q; He, C; Ito, S; Shen, L; Swenberg, JA; Wu, SC; Zhang, Y | 1 |
| Guo, JU; Ming, GL; Song, H; Su, Y; Zhong, C | 1 |
| Cohen-Karni, D; Guan, S; Pradhan, S; Quimby, A; Roberts, RJ; Wang, H; Wilson, G; Zheng, Y; Zhu, Z | 1 |
| Cheng, AW; Choi, SW; Dawlaty, MM; Ganz, K; Gao, Q; Hu, YC; Jaenisch, R; Kim, J; Markoulaki, S; Page, DC; Powell, BE | 1 |
| Chen, Z; Dai, Q; Ding, J; He, C; He, YF; Jia, Y; Li, BZ; Li, L; Li, X; Li, Z; Liu, P; Song, CX; Sun, Y; Tang, Q; Wang, Y; Xu, GL; Zhang, K | 1 |
| Ku, CS; Naidoo, N; Soong, R; Wu, M | 1 |
| Huang, TT; Li, Y; Pu, XY; Tang, H; Yamamura, KI | 1 |
| Cheng, X; Horton, JR; Upadhyay, AK; Zhang, X | 1 |
| Kohli, RM; Nabel, CS | 1 |
| Deng, Z; Gu, TP; Guo, F; He, X; Iqbal, K; Jin, SG; Li, J; Liu, W; Pfeifer, GP; Shi, L; Shi, YG; Szabó, PE; Wu, HP; Xie, ZG; Xu, GF; Xu, GL; Yang, H | 1 |
| Argani, P; Chaux, A; De Marzo, AM; Esopi, DM; Gerber, J; Haffner, MC; Iacobuzio-Donahue, C; Meeker, AK; Nelson, WG; Netto, GJ; Pellakuru, LG; Toubaji, A; Yegnasubramanian, S | 1 |
| Barrientos, EY; Torres, AL; Wrobel, K | 1 |
| Fujii, S; Goto, K; Hirono, S; Kato, D; Niwa, O; Takatsu, A | 1 |
| Ikeda, S; Nakamura, A; Okamoto, A; Sugizaki, K; Yanagisawa, H | 1 |
| Abraham, CR; King, GD; Rosene, DL | 1 |
| Inoue, A; Zhang, Y | 1 |
| Kohli, RM; Manning, SA; Nabel, CS | 1 |
| Chang, Q; Cheng, X; Dai, Q; Gearing, M; Godley, LA; He, C; Irier, H; Jin, P; Levey, AI; Li, X; Li, Y; Song, CX; Szulwach, KE; Upadhyay, AK; Vasanthakumar, A; Wu, H | 1 |
| Chase, KA; Dong, E; Gavin, DP; Guidotti, A; Matrisciano, F; Sharma, RP | 1 |
| Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y | 1 |
| Carell, T; Deiml, CA; Gnerlich, FA; Karaghiosoff, K; Koch, SC; Lischke, U; Münzel, M; Pfaffeneder, T; Stathis, D | 1 |
| Branco, MR; Ficz, G; Reik, W | 1 |
| Chang, Q; Chestnut, BA; Lesuisse, C; Martin, LJ; Price, A; Wong, M | 1 |
| Clark, TA; Dai, Q; He, C; Kislyuk, A; Korlach, J; Lu, XY; Song, CX; Turner, SW | 1 |
| Dixon, JM; Dunican, D; Harrison, DJ; Katz, E; Meehan, RR; Nestor, CE; Ottaviano, R; Reddington, J; Reinhardt, D; Sproul, D | 1 |
| Flax, JD; Soloway, PD | 1 |
| Paszkowski, J; Reinders, J | 1 |
| Dai, Q; He, C; Inoue, A; Shen, L; Zhang, Y | 1 |
| Acevedo, LG; Jelinek, MA; Sanz, A | 1 |
| Christensen, J; Helin, K; Williams, K | 1 |
| Carrillo-de Santa Pau, E; Matarese, F; Stunnenberg, HG | 1 |
| Chen, PB; Dong, X; Ee, LS; Fazzio, TG; Hung, JH; Li, R; Rando, OJ; Weng, Z; Yildirim, O | 1 |
| Kolb-Bachofen, V; Kremer, D; Metzger, S | 1 |
| Salbert, G; Weber, M | 1 |
| Cuddapah, S; Freudenberg, JM; Ghosh, S; Hu, G; Jothi, R; Lackford, BL; Li, R; Wade, PA; Yellaboina, S; Zheng, X | 1 |
| Bitinaite, J; Pradhan, S; Terragni, J; Zheng, Y | 1 |
| Carell, T; Eigenbrod, S; Feiden, W; Globisch, D; Hackner, B; Kraus, TF; Kretzschmar, HA; Müller, M; Münzel, M; Pfaffeneder, T; Schüller, U; Wagner, M; Widmann, D | 1 |
| Tsukada, Y | 1 |
| Chen, Y; Gao, F; Guan, J; Li, Z; Su, L; Tang, B; Wang, Z; Yin, Y; Zhang, P; Zhang, S | 1 |
| Chouliaras, L; Hof, PR; Keitel, S; Kenis, G; Rutten, BP; Schmitz, C; Steinbusch, HW; van den Hove, DL; van Os, J | 1 |
| Chouliaras, L; Rutten, BP; van den Hove, DL | 1 |
| Dahl, JA; Klungland, A; Ougland, R; Robertson, AB | 1 |
| Irier, HA; Jin, P | 1 |
| Aburatani, H; Asaoka, Y; Ijichi, H; Koike, K; Kudo, Y; Nagae, G; Tateishi, K; Yamamoto, K; Yamamoto, S; Yoshida, H | 1 |
| Agirre, X; Alvarez, S; Boultwood, J; Calasanz, MJ; Cross, NC; Cruz Cigudosa, J; Delabesse, E; Fernandez-Mercado, M; Garate, L; Martín-Subero, JI; Martínez-Calle, N; Pérez, C; Prósper, F; Rifon, J; Segura, V; Varea, S; Wainscoat, JS | 1 |
| Chang, Y; Cheng, X; Hashimoto, H; Howerton, SB; Liu, Y; Upadhyay, AK; Vertino, PM; Zhang, X | 1 |
| Bai, F; Guan, KL; Ling, ZQ; Liu, J; Liu, Y; Ma, SH; Xiong, Y; Xu, ZD; Yang, H; Ye, D; Zhang, JY; Zhu, HG | 1 |
| Almeida, RD; De Sousa, PA; Johnson, AD; Loose, M; Ruzov, A; Sottile, V | 1 |
| Almeida, RD; Denning, C; Gering, M; Johnson, AD; Loose, M; Matsa, E; Ruzov, A; Sottile, V; Young, L | 1 |
| Chen, H; Dzitoyeva, S; Manev, H | 3 |
| Basu, S; Lavania, S; Lavania, UC; Misra, NK; Mukai, Y; Srivastava, S | 1 |
| Dunn, JJ; He, C; Kumaran, D; Song, CX; Yao, Q | 1 |
| Karlic, H; Klaushofer, K; Spitzer, S; Thaler, R; Varga, F | 1 |
| Balasubramanian, S; Booth, MJ; Branco, MR; Ficz, G; Krueger, F; Oxley, D; Reik, W | 1 |
| Begley, MC; Drohat, AC; Maiti, A; Manvilla, BA; Toth, EA | 1 |
| Bocker, MT; Breiling, A; Lyko, F; Musch, T; Raddatz, G; Tuorto, F; Xu, M; Yang, FC | 1 |
| Shi, YG; Tan, L | 1 |
| Rugg-Gunn, PJ | 1 |
| Dai, Q; He, C; Hon, GC; Jin, P; Kim, A; Li, X; Min, JH; Park, B; Ren, B; Shen, Y; Song, CX; Szulwach, KE; Yu, M; Zhang, L | 1 |
| Cang, J; Huang, N; Tan, L; Wang, H; Xue, Z | 1 |
| Cai, C; Chen, L; Kang, JX; Xie, A; Ye, X; Zhang, J; Zhang, L; Zhou, K | 1 |
| Gao, KR; Yu, SY; Zhang, YX | 1 |
| Becker, A; Denkhaus, D; Freihoff, D; Freihoff, J; Gessi, M; Hammes, J; Isselstein, LJ; Luxen, D; Müller, T; Pietsch, T; Simon, M; Waha, A; zur Mühlen, A | 1 |
| Aguirre-Lavin, T; Beaujean, N; Boulesteix, C; Debey, P; Lehmann, G; Salvaing, J | 1 |
| Guz, J; Jurgowiak, M; Oliński, R | 1 |
| Inoue, K; Liu, YJ; Matoba, S; Nakamura, T; Nakano, T; Nakashima, H; Ogura, A; Shinkai, Y; Tachibana, M; Umehara, H | 1 |
| Avner, S; Barloy-Hubler, F; Bizot, M; Durand, E; Eeckhoute, J; Froguel, P; Gheeraert, C; Lefebvre, P; Lucchetti-Miganeh, C; Madigou, T; Métivier, R; Oger, F; Palierne, G; Percevault, F; Péron, CL; Salbert, G; Sérandour, AA; Staels, B | 1 |
| Chouliaras, L; Delbroek, L; Prickaerts, J; Rostamian, S; Rutten, BP; Sierksma, AS; Steinbusch, HW; van den Hove, DL | 1 |
| Eberhart, CG; Haffner, MC; Nelson, WG; Orr, BA; Yegnasubramanian, S | 1 |
| Klimašauskas, S; Kriukienė, E; Liutkevičiūtė, Z | 1 |
| Couvé, S; Grin, I; Henriot, V; Ishchenko, AA; Moréra, S; Saparbaev, M; Vigouroux, A | 1 |
| Wilkinson, J | 1 |
| Leonard, K; Lloyd, AJ; López, CM; Wilkinson, MJ | 1 |
| Berger, SL; Bonasio, R; Ding, Y; Jin, L; Jin, Z; Li, Q; Lian, J; Liebig, J; Mutti, NS; Reinberg, D; Shen, SS; Wang, J; Wang, W; Wang, Z; Wen, P; Xiang, H; Zhang, G; Zhang, P; Zhao, H | 1 |
| Balasubramanian, S; Beraldi, D; Booth, MJ; Branco, MR; Burgess, HE; Ficz, G; Murat, P; Oxley, D; Raiber, EA; Reik, W | 1 |
| Ando, Y; Furuhata, E; Hasegawa, R; Hayashizaki, Y; Kubosaki, A; Shin, JW; Simon, C; Suzuki, H; Suzuki, T; Tomaru, Y | 1 |
| Cai, C; Chen, L; Zhang, L | 1 |
| Kinney, SR; Pradhan, S | 1 |
| Belsham, D; Blencowe, BJ; Irimia, M; Jia, P; Kapranov, P; Khare, T; Klimasauskas, S; Koncevicius, K; Kriukiene, E; Kustra, R; Labrie, V; Liutkeviciute, Z; Moréra, S; Nazarians, A; Pai, S; Pal, M; Petronis, A; Ptak, C; Tice, R; Tochigi, M; Wang, SC; Wong, AH; Xia, M | 1 |
| Ceol, C; Dresser, K; Duncan, LM; Fang, R; Houvras, Y; Hu, D; Hu, Y; Kaiser, UB; Kakavand, H; Khorasani, AJ; Kleffel, S; Larson, A; Lee, CW; Lezcano, C; Lian, BQ; Lian, CG; Mihm, MC; Murphy, GF; Neiswender, J; Schatton, T; Scolyer, RA; Shi, YG; Tan, L; Thompson, JF; Woda, BA; Wu, F; Xu, W; Xu, Y; Yang, Y; Zhan, Q; Zon, LI | 1 |
| Miller, AK; Schüler, P | 1 |
| Huang, Y; Pastor, WA; Rao, A; Zepeda-Martínez, JA | 1 |
| Agarwal, S; Henderson, HR; Huang, Y; Pastor, WA; Rao, A | 1 |
| Ding, W; Xing, TY | 1 |
| Bolognani, F; Hackett, JA; Lempiäinen, H; Meehan, RR; Moggs, JG; Müller, A; Nestor, CE; Oakeley, EJ; Reinhardt, D; Schübeler, D; Terranova, R; Thomson, JP | 1 |
| Duan, R; He, C; Jin, P; Li, X; Lin, L; Pan, Q; Song, CX; Szulwach, KE; Wang, T; Warren, ST; Wu, H | 1 |
| He, C; Jin, P; Li, Y; Song, CX | 1 |
| Fu, Y; He, C | 1 |
| Kawamura, F; Kimura, H; Kubiura, M; Okano, M; Tada, M | 1 |
| Bellini, M; Jones, P; Morgan, GT | 1 |
| He, C; Hon, GC; Jin, P; Ren, B; Song, CX; Szulwach, KE; Yu, M | 1 |
| Down, TA; Hackett, JA; Lee, C; Murakami, K; Sengupta, R; Surani, MA; Zylicz, JJ | 1 |
| Du, J; Guo, Z; Liu, Y; Tang, B; Wang, Y; Wu, Y; Yang, L; Zhang, Y | 1 |
| Ayata, P; Dewell, S; Heintz, N; Kriaucionis, S; Mellén, M | 1 |
| Arita, K; Ariyoshi, M; Kato, T; Kimura, H; Kinoshita, M; Otani, J; Shirakawa, M; Suetake, I; Tajima, S | 1 |
| Bapat, B; Olkhov-Mitsel, E | 1 |
| Chen, ML; Feng, YQ; Huang, W; Liu, SM; Qi, JH; Shen, F; Wang, Y; Yuan, BF | 1 |
| Borgaro, JG; Cheng, X; Guan, S; Jolyon, T; Liu, Y; Pradhan, S; Sun, D; Sun, Z; Terragni, J; Wang, H; Yu, L; Zheng, Y; Zhu, Z | 1 |
| Barrasa, MI; Breiling, A; Cheng, AW; Dawlaty, MM; Faull, KF; Gao, Q; Jaenisch, R; Le, T; Li, Z; Lyko, F; Powell, BE; Raddatz, G; Xu, M | 1 |
| Bernard, O; Calonne, E; Daniels, DL; Dawson, MA; Defrance, M; Delatte, B; Deplus, R; Fuks, F; Levine, RL; Méndez, J; Mercher, T; Murphy, N; Putmans, P; Schwinn, MK; Shih, AH; Solary, E; Urh, M; Volkmar, M | 1 |
| Albasanz, JL; Barrachina, M; Blanch, M; Ferrer, I; Martín, M; Pereira-Veiga, T; Pérez-Navarro, E; Tyebji, S; Villar-Menéndez, I | 1 |
| Chen, CC; Shen, CK; Wang, KY | 1 |
| Hong, K; Inoue, A; Liu, R; Shen, L; Yamaguchi, S; Zhang, K; Zhang, Y | 1 |
| Hahn, MA; Jiang, Y; Jin, SG; Jui, J; Li, AX; Lu, Q; Pfeifer, GP; Qiu, R; Wang, J; Wu, X; Zhang, H | 1 |
| Mariappa, D; Pathak, S; van Aalten, DM | 1 |
| Huang, N; Kong, L; Schwartz, L; Shi, Y; Shi, YG; Tan, L; Wu, F; Xiong, L; Xu, W; Xu, Y; Zheng, L | 1 |
| Chen, Y; Oztürk, NC; Resendiz, M; Zhou, FC | 1 |
| Calvopiña, JH; Chen, PY; Clark, AT; Fan, G; Faull, K; Feng, S; Huang, Y; Jacobsen, SE; Le, T; Lee, SA; Nee, K; Pellegrini, M; Rao, A; Vincent, JJ; Yoon, AJ | 1 |
| Badoo, M; Baribault, C; Crain, CM; Crawford, GE; Ehrlich, M; Gertz, J; Lacey, M; Myers, RM; Pradhan, S; Song, L; Terragni, J; Tsumagari, K; Varley, KE | 1 |
| Liu, S; Liu, X; Luo, Y; Pei, M; Shen, J; Xiao, L; Xu, Y; Yi, Y; Zhang, G; Zheng, W; Zhong, H | 1 |
| Bauer, C; Boelens, R; Brinkman, AB; Carell, T; Eberl, HC; Gnerlich, F; Jansen, PW; Khan, F; Leonhardt, H; Lephikov, K; Mensinga, A; Müller, M; Müller, U; Münzel, M; Pfaffeneder, T; Smits, AH; Spruijt, CG; van Ingen, H; Vermeulen, M; Wagner, M; Walter, J | 1 |
| Andreazza, AC; Carvalho, AF; Machado-Vieira, R; Moreno, RA; Soeiro-de-Souza, MG; Young, LT | 1 |
| Bagci, H; Brown, KE; Dawlaty, MM; Feytout, A; Fisher, AG; Hajkova, P; Jaenisch, R; Kriaucionis, S; Landeira, D; Leitch, HG; Merkenschlager, M; Mooijman, D; Piccolo, FM; Soza-Ried, J; Tada, T | 1 |
| Gambichler, T; Sand, M; Skrygan, M | 1 |
| Borgaro, JG; Zhu, Z | 1 |
| Shen, L; Zhang, Y | 1 |
| Koh, KP; Rao, A | 1 |
| Cai, T; Chen, J; Gao, S; Gao, Y; Huang, B; Huang, H; Jiang, Y; Kang, L; Kou, X; Li, K; Liu, W; Liu, X; Lu, Z; Wang, H; Wu, T; Xu, Z; Yao, C; Zhang, Y | 1 |
| Gao, F; Gao, Z; Han, X; Huang, X; Lin, Z; Lu, H; Luo, H; Wang, J; Wen, B; Xia, Y; Yang, H; Yao, Y; Yi, N; Zhang, J; Zhang, X; Zhou, B | 1 |
| Godley, LA; Madzo, J; Vasanthakumar, A | 1 |
| Cai, C; Chen, LY; Kang, JX; Xie, AM; Ye, XX; Zhang, JJ; Zhang, LJ; Zhang, LT | 1 |
| Court, BL; Minor, EA; Wang, G; Young, JI | 1 |
| Bayley, H; Gong, L; Li, WW | 1 |
| Amano, T; Anzai, M; Hatanaka, Y; Hosoi, Y; Kato, H; Kishigami, S; Matsumoto, K; Mitani, T; Nishihara, T; Nishikawa, S; Shimizu, N; Shin, SW; Tokoro, M | 1 |
| Guibert, S; Weber, M | 1 |
| Tajbakhsh, J | 1 |
| Hunter, JM; Lempiäinen, H; Meehan, RR; Moggs, JG; Müller, A; Terranova, R; Thomson, JP | 1 |
| D'Alessio, AC; Diep, D; Fung, HL; Shen, L; Wu, H; Yamaguchi, S; Zhang, K; Zhang, Y | 1 |
| Dai, Q; Fu, Y; Gao, J; He, C; Jin, P; Li, L; Li, Y; Lin, L; Liu, P; Mao, SQ; Poidevin, M; Song, CX; Street, C; Szulwach, KE; Wu, H; Xu, GL | 1 |
| Chen, X; Hong, T; Hu, J; Mao, W; Wang, S; Xing, X; Zhou, X | 1 |
| Akrap, I; Feliciello, I; Parazajder, J; Ugarković, D | 1 |
| Guo, C; Han, C; Liao, YQ; Lin, X; Luo, HR; Sun, Q; Tang, TS; Wang, D; Wang, F; Wang, JQ; Wu, YS; Xie, W; Yang, Y; Yang, YG; Zhu, S | 1 |
| Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z | 1 |
| De Marzo, AM; Ghosh, S; Haffner, MC; Lotan, TL; Nelson, WG; Pellakuru, LG; Yegnasubramanian, S | 1 |
| Jin, SG; Kim, SI; Pfeifer, GP | 1 |
| Chu, JM; Feng, YQ; Huang, W; Tang, Y; Xing, XW; Xiong, J; Yuan, BF; Zhou, X | 1 |
| Alesiani, F; Alfonsi, S; Berardinelli, E; Biagetti, S; Catarini, M; Centurioni, R; Costantini, B; Giantomassi, F; Goteri, G; Leoni, P; Mariani, M; Olivieri, A; Poloni, A; Serrani, F; Stramazzotti, D; Trappolini, S; Zizzi, A | 1 |
| Ananiev, G; Chamberlain, SJ; Chang, Q; Chen, IP; Dodd, A; Goldlust, IS; Gong, H; Han, JW; He, C; Jin, P; Li, X; Li, Y; Lin, L; Rudd, MK; Song, CX; Szulwach, KE; Wang, T; Warren, ST; Wu, H; Yoon, YS; Yu, M | 1 |
| Li, Y; O'Neill, C | 1 |
| Cong, R; Jia, Y; Li, R; Parvizi, N; Sun, Q; Yang, X; Zhao, R | 1 |
| Andreesen, R; Gebhard, C; Klug, M; Rehli, M; Schmidhofer, S | 1 |
| Chen, T; Zhao, H | 1 |
| Hunter, JM; Meehan, RR; Thomson, JP | 1 |
| Adema, C; Bulla, J; Cosseau, C; Dheilly, N; Fneich, S; Grunau, C; Reichelt, M; Rognon, A | 1 |
| Hornick, JL; Mason, EF | 1 |
| Ebenstein, Y; Grunwald, A; Hoch, R; Michaeli, Y; Shahal, T; Torchinsky, D | 1 |
| Gan, H; Han, C; He, C; Liao, S; Lin, X; Liu, J; Ma, T; Song, CX; Tang, F; Wang, M; Wen, L | 1 |
| He, C; Lu, X | 1 |
| Aston, KI; Cairns, BR; Carrell, DT; Jenkins, TG | 1 |
| Blaschke, K; Ebata, KT; Goyal, P; Hirst, M; Karimi, MM; Laird, DJ; Lorincz, MC; Mahapatra, S; Ramalho-Santos, M; Rao, A; Tam, A; Zepeda-Martínez, JA | 1 |
| Arnovitz, S; Chen, J; Chen, P; Dawlaty, M; Elkahloun, AG; Gurbuxani, S; He, C; Hong, GM; Huang, H; Jaenisch, R; Jiang, X; Jin, P; Li, Y; Li, Z; Lin, L; Liu, PP; Mulloy, JC; Neilly, MB; Rowley, JD; Song, CX; Street, C; Sun, M; Szulwach, K; Wang, J; Wunderlich, M; Xu, M; Yang, FC | 1 |
| Błasiak, J; Głowacki, S | 1 |
| Lowry, WE | 1 |
| Behrens, MM; Dwork, AJ; Ecker, JR; Esteller, M; Haghighi, FG; He, C; Heyn, H; Hu, S; Huang, Y; Johnson, ND; Lister, R; Lucero, J; Mukamel, EA; Nery, JR; Puddifoot, CA; Rao, A; Schultz, MD; Sejnowski, TJ; Tonti-Filippini, J; Urich, M; Wu, JC; Yu, M | 1 |
| De Jonge, CJ | 1 |
| Ala, U; Beringer, G; Brikbak, NJ; Cantley, LC; Ng, C; Pandolfi, PP; Poliseno, L; Richardson, AL; Song, MS; Song, SJ; Webster, K; Yuan, X | 1 |
| Bhagat, TD; Bhattacharyya, S; Campbell, N; Christopeit, M; Godley, L; Greally, JM; Maitra, A; Mazdo, J; Nischal, S; Parekh, S; Steidl, U; Suzuki, M; Vasanthakumar, A; Verma, A; Yu, Y | 1 |
| Nawy, T | 1 |
| Hirose, K; Kikuchi, Y; Shimoda, N | 1 |
| Fujiki, K; Kano, F; Murata, M; Sato, R; Shinoda, A; Shirahige, K | 1 |
| Jin, P; Yao, B | 1 |
| Gabel, HW; Greenberg, ME | 1 |
| Bressler, JP; Coulter, JB; O'Driscoll, CM | 1 |
| Barragan, I; Ingelman-Sundberg, M; Ivanov, M; Kacevska, M; Kals, M; Kasuga, K; Metspalu, A; Milani, L; Rane, A | 1 |
| Blacque, O; Renciuk, D; Spingler, B; Vorlickova, M | 1 |
| Hong, EE; Qu, J; Smith, AD; Song, Q; Zhou, M | 1 |
| Allen, WE; Barnea, G; Colquitt, BM; Lomvardas, S | 1 |
| Cho, IH; Chowdhury, B; Cui, Y; Irudayaraj, J | 1 |
| He, N; Hou, P; Ji, M; Jin, W; Shi, B; Wu, K; Yang, Q | 1 |
| Carell, T; Hackner, B; Höfner, G; Kashiwazaki, G; Ochsenfeld, C; Pfaffeneder, T; Sadeghian, K; Schiesser, S; Schröder, AS; Steigenberger, B; Steinbacher, J; Wanner, KT | 1 |
| Bogomazova, AN; Kiselev, SL; Lagarkova, MA; Nekrasov, ED; Panova, AV | 1 |
| Incarnato, D; Krepelova, A; Neri, F; Oliviero, S; Pagnani, A; Parlato, C; Rapelli, S; Zecchina, R | 1 |
| Kubota, T; Li, Y; Miyanari, Y; Nitta, H; Ohashi, H; Okamoto, A; Sasaki, H; Shirane, K | 1 |
| Chen, Y; Ding, F; Guo, P; Hong, T; Ma, J; Wang, T; Wu, F; Wu, J; Xing, X; Zhou, X | 1 |
| Bender, A; Weber, M | 1 |
| Meehan, RR; Moggs, JG; Thomson, JP; Wolf, CR | 1 |
| Balasubramanian, S; Bell, NM; Beraldi, D; Booth, MJ; Branco, MR; Ost, TW; Reik, W | 1 |
| Dickson, KM; Gustafson, CB; Wang, G; Young, JI; Züchner, S | 1 |
| Al-Mahdawi, S; Mouro Pinto, R; Pook, MA; Sandi, C | 1 |
| Ballestar, E; Christensen, J; de la Rica, L; García, M; Gómez-Vaquero, C; Helin, K; Hernando, H; Islam, AB; Rodríguez-Ubreva, J; Urquiza, JM | 1 |
| Fu, B; Long, Y; Peng, S; Tian, T; Wang, S; Zhang, X; Zhou, X | 1 |
| Feng, YQ; Liu, YL; Vargas, M; Wang, Y; Xing, XW; Yuan, BF; Zhou, X | 1 |
| Bollig-Fischer, A; Cao, X; Chen, CC; Cingolani, P; Coon, M; Garfinkel, MD; Huang, Y; Hudson, ME; Khetani, RS; Land, S; Robinson, GE; Ruden, DM; Sammak, A; Zhong, S | 1 |
| Kang, TW; Kim, HJ; Kim, M; Kim, SY; Kim, YS; Lee, D; Lee, SH; Park, JL; Park, YK; Rhee, YH | 1 |
| Bitinaite, J; Chin, HG; Corrêa, IR; Dai, N; Pradhan, S | 1 |
| Galloway, JN; Jin, P; Lin, L; Nelson, DL; Street, RC; Wu, H; Yao, B; Zalewski, ZA | 1 |
| Fu, X; Hu, J; Huang, W; Jin, L; Ku, HT; Luo, A; Riggs, AD; Tsark, WM; Wang, X; Zheng, X | 1 |
| Chen, J; Chen, S; Cheng, J; D'Alessio, AC; Ding, Y; Guo, S; Guo, Y; Heydari, K; Hysolli, E; Li, D; Liu, C; Liu, J; Lu, J; Mastriano, SJ; Megyola, CM; Pan, W; Park, IH; Roden, CA; Yao, H; Zhang, Y; Zhou, XL | 1 |
| Hasséus, B; Jäwert, F; Kjeller, G; Larsson, L; Magnusson, B; Sand, L | 1 |
| Feng, YQ; Huang, JT; Huang, W; Liu, SM; Liu, YJ; Qi, JH; Shen, F; Yuan, BF; Zhou, X | 1 |
| Pettitt, BM; Sowers, LC; Theruvathu, JA; Yin, YW | 1 |
| An, R; Ming, GL; Shin, J; Song, H; Weng, YL | 1 |
| Kohli, RM; Zhang, Y | 1 |
| Benson, M; Meehan, RR; Nestor, CE; Reddington, JP | 1 |
| Meehan, RR; Nestor, CE | 1 |
| Mandarano, AH; Militello, KT; Simon, RD; Varechtchouk, O | 1 |
| Bartlett, JJ; Brinkerhoff, H; Derrington, IM; Gundlach, JH; Langford, KW; Laszlo, AH; Nova, IC; Pavlenok, M; Samson, JM | 1 |
| Abu-Shumays, R; Akeson, M; Baatar, B; Karplus, K; Schreiber, J; Vivian, JT; Wescoe, ZL | 1 |
| Ashida, A; Hayashi, K; Kiniwa, Y; Koga, H; Ogawa, E; Okuyama, R; Takazawa, Y; Uchiyama, A; Uchiyama, R; Uhara, H | 1 |
| Fu, B; Guo, G; Huang, R; Mao, W; Wang, J; Xing, X; Zhou, X | 1 |
| Dunican, DS; Hunter, JM; Meehan, RR; Moggs, JG; Nestor, CE; Terranova, R; Thomson, JP | 1 |
| Chong, Z; Huang, H; Jiang, G; Jin, KX; Li, C; Rendtlew Danielsen, JM; Song, M; Song, SH; Sun, BF; Wang, H; Wang, X; Wu, D; Xu, GL; Yang, Y; Yang, YG; Yin, R; Zhao, B; Zhao, C; Zhu, BZ | 1 |
| Cheng, X; Liu, Y; Olanrewaju, YO; Zhang, X | 1 |
| Li, L; Ye, C | 1 |
| Challen, GA; Chavez, L; Chen, R; Darlington, GJ; Godley, LA; Goodell, MA; Göttgens, B; Gunaratne, P; Hannah, R; Huang, Y; Jeong, M; Kim, SB; Ko, M; Lee, JS; Li, W; Luo, M; Rao, A; Rodriguez, B; Sun, D; Wang, H; Yang, L; Zhang, X | 1 |
| Harrison, DJ; Laird, A; Meehan, RR; Thomson, JP | 1 |
| Brown, T; El-Sagheer, AH; Kriaucionis, S; Lercher, L; McDonough, MA; Schofield, CJ; Thalhammer, A | 1 |
| Fragou, A; Fragou, D; Kouidou, S; Kovatsi, L; Njau, S; Samanidou, V | 1 |
| Chen, Y; Hu, J; Weng, X; Wu, F; Xing, X; Xu, J; Xu, X; Xu, Z; Zhou, X | 1 |
| Cao, Z; Li, N; Li, Y; Wu, R; Zhang, Y; Zhou, N | 1 |
| Cao, X; Chen, CC; He, C; Song, CX; Wang, T; Xiao, S; Xie, D; Zhong, S | 1 |
| Endo, TA; Kawakami, T; Kimura, H; Koseki, H; Mishima, Y; Otani, J; Sharif, J; Shirakawa, M; Suetake, I; Tajima, S | 1 |
| Li, J; Liu, L; Wu, HC; Yang, C; Zhao, K | 1 |
| Barciszewski, J; Gabryelska, MM | 1 |
| Burger, L; Feldmann, A; Gaidatzis, D; Ivanek, R; Murr, R; Schübeler, D | 1 |
| Chappell, J; Dalton, S; Jin, P; Lin, L; Matlock, BK; Singh, AM; Tang, J; Trost, R; Wang, T; Weller, KP; Wu, H; Zhao, S | 1 |
| Caces, DBD; Duszynski, R; Godley, LA; Grossman, R; He, C; Lahn, BT; Lavelle, D; Lepore, JB; Levine, RL; Liu, H; Looney, TJ; Macrae, T; Madzo, J; Raumann, B; Rodriguez, A; Shih, AH; Song, CX; Sundaravel, S; Vasanthakumar, A; Verma, A; Wickrema, A; Yu, M; Yu, Y; Zhang, L | 1 |
| Fronhoffs, F; Grewe, MJ; Haas, N; Heukamp, LC; Honecker, F; Kristiansen, G; Nettersheim, D; Schorle, H; Waha, A | 1 |
| Coppieters, N; Curtis, MA; Dieriks, BV; Dragunow, M; Faull, RL; Lill, C | 1 |
| Iwamoto, K; Kato, T | 1 |
| Dresser, KA; Larson, AR; Lezcano, C; Lian, CG; Mihm, MC; Murphy, GF; Scolyer, RA; Shi, YG; Thompson, JF; Woda, BA; Yosufi, B; Zhan, Q | 1 |
| Cheng, X; Corrêa, IR; Dai, N; Fu, ZQ; Hashimoto, H; Pais, JE; Saleh, L; Zhang, X; Zheng, Y | 1 |
| Gao, W; Hou, J; Li, J; Li, P; Liu, X; Wong, J; Zhang, Q | 1 |
| Guan, M; Li, X; Sun, W | 1 |
| Cowley, AW; Liang, M; Liu, P; Liu, Y; Yang, C | 1 |
| Chen, Y; Cook, EH; Dong, E; Grayson, DR; Guidotti, A; Zhubi, A | 1 |
| Bhutani, N; Dhulipala, L; Rath, M; Smeriglio, P; Taylor, SE | 1 |
| Hasegawa, J; Miura, N; Shomori, K; Tsuno, S; Wang, X | 1 |
| Haqqi, TM; Haseeb, A; Makki, MS | 1 |
| Rudenko, A; Tsai, LH | 1 |
| de Souza, N | 1 |
| Alisch, RS; Brown, RM; Chopra, P; Garthwaite, MA; Golos, TG; Hatch, A; Papale, LA; Roseboom, PH; Warren, ST; White, AT | 1 |
| Ling, ZQ; Wu, YC | 1 |
| Guo, H; He, C; Hou, Y; Li, R; Li, X; Liu, X; Qiao, J; Song, C; Tan, Y; Tang, F; Wang, Y; Wen, L; Wu, X; Xie, J; Yan, L; Yu, M; Zhang, Y; Zhao, Y; Zhu, P | 1 |
| Barbier, E; Breton, J; Couté, Y; Gasparutto, D; Kraut, A; Lafaye, C; Miscioscia, A; Plo, I; Ravanat, JL; Saint-Pierre, C | 1 |
| Cui, D; Dai, J; Jin, W; Ju, G; Ma, Y; Macklin, WB; Mi, Y; Zhao, X | 1 |
| Rao, A; Tsagaratou, A | 1 |
| Braeckmans, K; Forier, K; Heras, S; Rombouts, K; Van Soom, A | 1 |
| Deng, Q; Huang, D; Jin, S; Yang, Q; Zhou, P | 1 |
| Bochtler, M; Czapinska, H; Kazrani, AA; Kowalska, M | 1 |
| Aravind, L; Chen, W; Dai, Q; Fu, Y; He, C; Hu, J; Iyer, LM; Wang, G; Yu, M; Zhang, L | 1 |
| Bennett, AJ; Massart, R; Provencal, N; Suderman, M; Suomi, S; Szyf, M; Yi, C | 1 |
| Eichman, BF; Huh, JH; Jang, H; Shin, H | 1 |
| Crawford, GE; Ehrlich, M; Lacey, M; Pradhan, S; Song, L; Sun, Z; Terragni, J; Zhang, G | 1 |
| Chouliaras, L; Condliffe, D; Cooper, J; Fernandes, C; Lovestone, S; Lunnon, K; Mill, J; Patel, Y; Proitsi, P; Schalkwyk, L; Troakes, C; Wong, A | 1 |
| Jiang, G; Li, C; Liu, B; Liu, Z; Song, M; Wang, H; Yin, R; Zhao, B; Zhao, C | 1 |
| Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C | 1 |
| Cao, CH; Chen, JJ; Cui, ZZ; Dai, Y; Ou, ML; Sui, WG; Sun, YF; Tan, QP; Xue, W; Yan, Q; Yang, M; Zou, TX | 1 |
| Dai, Z; Ding, ZB; Fan, J; Jin, L; Liu, WR; Peng, YF; Qiu, SJ; Shen, YH; Shi, YH; Tian, MX; Yang, LX; Zhou, J | 1 |
| Annibali, V; Bacalini, MG; Caiafa, P; Calabrese, R; Ciccarone, F; Franceschi, C; Guastafierro, T; Mechelli, R; Ricigliano, VA; Salvetti, M; Valentini, E; Zampieri, M | 1 |
| Brown, T; Fox, KR; Kimber, ST | 1 |
| Niederberger, C | 1 |
| Baker-Andresen, D; Bredy, TW; D'Alessio, A; Flavell, CR; Li, X; Wei, W; Widagdo, J; Zhang, Y; Zhao, QY | 1 |
| Cole, SA; Fallin, MD; Francesconi, KA; Goessler, W; Guallar, E; Laclaustra, M; Ledesma, M; Leon, M; Navas-Acien, A; Pollak, J; Shang, Y; Tang, WY; Tellez-Plaza, M; Umans, JG | 1 |
| Ji, D; Lin, K; Song, J; Wang, Y | 1 |
| Cui, DX; Fu, HL; Hou, P; Jin, WL; Li, BJ; Lu, LG; Ma, Y | 1 |
| Chen, C; He, N; Hou, P; Ji, M; Jin, T; Liu, S; Liu, W; Qiang, W; Shi, B; Yang, Q | 1 |
| Aluru, N; Ci, W; Duan, J; Gao, X; He, C; Huang, X; Li, G; Li, W; Liu, J; Lu, X; Tang, F; Wang, L; Yang, L; Zhang, J; Zhou, Q; Zhu, W | 1 |
| Wang, M; Wong, J; Xiong, J; Xu, RM; Yang, N; Zhou, T; Zhu, B | 1 |
| Hahn, MA; Jin, SG; Pfeifer, GP; Xiong, W | 1 |
| Delatte, B; Deplus, R; Fuks, F | 1 |
| Golla, JP; Mandal, A; Mann, IK; Rose, RB; Sayeed, SK; Vinson, C; Zhao, J | 1 |
| Bhagat, T; Bhattacharyya, S; Cohn, SL; Godley, LA; Madzo, J; Mariani, CJ; Nanduri, J; Prabhakar, NR; Vasanthakumar, A; Verma, A; Wenger, RH; Yesilkanal, A; Yu, Y | 1 |
| Brandmayr, C; Carell, T; Eisen, D; Hackner, B; Kashiwazaki, G; Kosmatchev, O; Kotljarova, O; Laube, SK; Leonhardt, H; Michalakis, S; Müller, M; Müller, U; Pfaffeneder, T; Raddaoui, N; Schär, P; Schiesser, S; Schuermann, D; Spada, F; Spruijt, CG; Steigenberger, B; Steinbacher, J; Truss, M; Vermeulen, M; Wagner, M | 1 |
| Bernstein, A; Chen, D; Cheng, Y; Jin, P | 1 |
| Cadet, J; Madugundu, GS; Wagner, JR | 1 |
| Cadet, J; Eriksson, LA; Grand, A; Jorge, N; Morell, C | 1 |
| Barton, MC; Estecio, MR; Issa, JP; Jelinek, J; Jin, C; Liang, S; Lu, Y | 1 |
| Calvo, X; Costa, D; Esteve, J; Monzó, M; Muñoz, C; Navarro, A; Nomdedeu, B; Nomdedeu, M; Peña, O; Pereira, A; Risueño, RM; Tejero, R | 1 |
| Church, GM; Esvelt, KM; Yaung, SJ | 1 |
| Ahsan, S; Ballester, LY; Eberhart, CG; Haffner, MC; Nazarian, J; Quezado, M; Raabe, EH; Rodriguez, FJ; Vaghasia, A; Warren, KE | 1 |
| Borgaro, JG; Cheng, X; Griggs, RM; Guan, S; Horton, JR; Quimby, A; Wilson, GG; Zhang, X; Zheng, Y; Zhu, Z | 1 |
| He, C; Shen, L; Song, CX; Zhang, Y | 1 |
| Collins, LB; Hanaoka, F; Ito, S; Iwai, S; Kanao, R; Koseki, H; Kuraoka, I; Masuda, Y; Masutani, C; Shibata, M; Shibutani, T; Swenberg, JA; Toda, M; Urabe, M | 1 |
| Hirota, S; Imai, Y; Matsuda, I | 1 |
| Filip, M; Frankowska, M; Sadakierska-Chudy, A | 1 |
| Choi, JH; Ho, T; Liu, C; Putiri, EL; Robertson, KD; Thompson, JJ; Tiedemann, RL | 1 |
| Aslanyan, MG; Boezeman, JB; Carell, T; de Witte, T; Halkes, CJ; Huls, G; Jansen, JH; Koorenhof-Scheele, TN; Kroeze, LI; Marie, JP; Massop, M; Suciu, S; van der Reijden, BA; van Rooij, A; Wevers, RA | 1 |
| Goodell, MA; Jeong, M | 1 |
| Amadori, S; Aslanyan, MG; Cilloni, D; da Silva-Coelho, P; de Witte, T; Jansen, JH; Koorenhof-Scheele, TN; Kroeze, LI; Labar, B; Langemeijer, SM; Marie, JP; Marijt, EW; Massop, M; Muus, P; Saglio, G; Stevens-Linders, E; Suciu, S; Tang, R; Tönnissen, E; van de Locht, LT; van der Heijden, A; van der Reijden, BA; van Hoogen, P; Willemze, R | 1 |
| Hata, K; Kobayashi, H; Kono, T; Sakashita, A; Sotomaru, Y; Wakai, T | 1 |
| Bulun, SE; Coon, JS; Dyson, MT; Monsivais, D; Moravek, MB; Navarro, A; Ono, M; Wei, JJ; Yin, P | 1 |
| Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R | 1 |
| Bailey, A; Chao, MR; Fragou, D; Hu, CW; Kouidou, S; Kovatsi, L; Zanos, P | 1 |
| Äijö, T; Huang, Y; Jacobsen, SE; Lähdesmäki, H; Lio, CW; Rao, A; Tsagaratou, A; Yue, X | 1 |
| Ebenstein, Y; Gilat, N; Michaeli, Y; Redy-Keisar, O; Shabat, D; Shahal, T | 1 |
| Amato, NJ; Cai, Q; Fu, L; Guerrero, CR; Ji, D; Jin, SG; Liu, S; Liu, Y; Niedernhofer, LJ; Pfeifer, GP; Wang, Y; Xu, GL; Zhong, N | 1 |
| Granter, SR; Guo, W; Laga, AC; Lee, JJ; Lian, CG; Murphy, GF; Saavedra, AP; Xu, S; Zhan, Q | 1 |
| Arab, K; Dienemann, H; Dyckhoff, G; Grummt, I; Herold-Mende, C; Lindroth, AM; Lukanova, A; Lundin, E; Meister, M; Niehrs, C; Oakes, C; Park, YJ; Plass, C; Risch, A; Schäfer, A; Weichenhan, D | 1 |
| Mikoshiba, Y; Ogawa, E; Okuyama, R; Uchiyama, A; Uchiyama, R; Uhara, H | 1 |
| Du, C; Goto, M; Kahyo, T; Konno, H; Kurabe, N; Matsushima, Y; Ohnishi, I; Shinmura, K; Sugimura, H; Suzuki, M; Tajima, S; Tanioka, F; Tao, H; Yamada, H | 1 |
| Bochtler, M; Kucharski, R; Maleszka, J; Maleszka, R; Misztal, K; Rafalski, D; Wojciechowski, M | 1 |
| Choi, I; Kaestner, KH; Kim, R; Lim, HW; Won, KJ | 1 |
| Huang, Y; Rao, A | 1 |
| Chen, T; Chen, Y; Frank, MY; Guo, W; Lian, CG; Liu, C; Liu, R; Murphy, GF; Xu, S; Yan, J | 1 |
| Amouroux, R; Hajkova, P; Hill, PW | 1 |
| Nakayama, A; Taketsugu, T; Yamazaki, S | 1 |
| Bibikova, M; Boland, MJ; Cabral-da-Silva, MC; Coleman, RL; Fan, JB; Glenn-Pratola, VL; He, C; Klotzle, B; Loring, JF; Nazor, KL; Peterson, SE; Schell, JP; Schmidt, U; Yu, M | 1 |
| Ficz, G; Gribben, JG | 1 |
| Irwin, RE; O' Neill, KM; Thakur, A; Walsh, CP | 1 |
| Hahn, MA; Pfeifer, GP; Szabó, PE | 1 |
| Antunes, C; Guedes, M; Marques, CJ; Santiago, M; Sousa, N | 1 |
| Balazs, R; Gami, P; Lashley, T; Li, A; Revesz, T; Valizadeh, N | 1 |
| Cai, C; Cheng, Y; Dave, R; Davis, TH; Irier, H; Jin, P; Lin, L; Street, RC; Yao, B | 1 |
| Li, X; Shu, Q; Sun, W; Zang, L | 1 |
| Tang, F; Wen, L | 1 |
| Hajkova, P; Lehner, B; Supek, F; Warnecke, T | 1 |
| Chung, TH; Cui, L; Jia, XY; Sun, X; Tan, D | 1 |
| Chung, TH; Jia, XY; Petterson, A; Sun, X; Tan, D | 1 |
| Mu, X; Peng, S; Shen, H; Wang, X; Zhang, J | 1 |
| Alamdar, A; Huang, Q; Liu, L; Martin, FL; Mu, X; Shen, H; Tian, M; Xu, W; Zhang, J | 1 |
| Du, T; Edsall, LE; He, C; Hon, GC; Jin, F; Kuan, S; Lee, AY; Mao, SQ; Ren, B; Selvaraj, S; Song, CX; Wang, BA; Xu, GL; Ye, Z; Yen, CA; Zhao, BS | 1 |
| Kriaucionis, S; Tahiliani, M | 1 |
| Akiyama, T; Ino, Y; Katou, Y; Koyama-Nasu, R; Kozuka-Hata, H; Masuda, K; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Ogawa, H; Oyama, M; Saito, N; Sakaguchi, Y; Sato, T; Shirahige, K; Suzuki, T; Takai, H; Todo, T; Toyoshima, C | 1 |
| James, SJ; Melnyk, S; Pavliv, O; Pogribny, IP; Shpyleva, S | 1 |
| Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC | 1 |
| De Sousa, PA; Gliddon, C; Horsburgh, K; Ruzov, A; Tsenkina, Y | 1 |
| Butter, C; Ciccone, NA; Mwangi, W; Nair, V; Ruzov, A; Smith, LP | 1 |
| Burghart, DR; De Souza, A; Kempf, W; Pfaltz, M; Tinguely, M | 1 |
| Fusser, M; Klungland, A; Robertson, AB; Robertson, J | 1 |
| Shen, L; Wu, H; Wu, X; Zhang, Y | 1 |
| Das, SK; Gao, F | 1 |
| Clish, CB; Erdmann, RM; Gehring, M; Souza, AL | 1 |
| Brazauskas, P; Kriaucionis, S | 1 |
| Bachman, M; Balasubramanian, S; Murrell, A; Uribe-Lewis, S; Williams, M; Yang, X | 1 |
| Hahn, MA; Li, AX; Pfeifer, GP; Wu, X | 1 |
| Chatterjee, A; Morison, IM; Rodger, EJ | 1 |
| Cho, IH; Chowdhury, B; Hahn, N; Irudayaraj, J | 1 |
| Walsh, C; Xu, G | 1 |
| Armani, AM; Hawk, RM | 1 |
| Guibourt, V; Kraus, TF; Kretzschmar, HA | 1 |
| Cai, JB; Dong, ZR; Fan, J; Gao, DM; Ke, AW; Qiu, SJ; Shi, GM; Sun, HC; Zhang, C; Zhang, PF; Zhou, J | 1 |
| Abdel-Wahab, O; Ahn, J; Aifantis, I; Alkalin, A; Ciminio, L; Dai, Q; Daniels, D; Ferrando, A; Figueroa, ME; Fuks, F; Godley, LA; He, C; Hricik, T; Levine, RL; Li, Y; Licht, JD; Lu, C; Madzo, J; Mason, CE; Melnick, A; Nimer, S; Paietta, E; Patel, J; Pronier, E; Rampal, R; Shih, A; Tallman, JE; Tallman, MS; Thompson, CB; Tosello, V; Tsai, JJ; Vasanthakumar, A; Ward, PS; Zhao, X | 1 |
| Sasnauskas, G; Zagorskaitė, E | 1 |
| Ailamazyan, EK; Baranov, VS; Bogdanova, MA; Chiryaeva, OG; Efimova, OA; Fedorova, ID; Gzgzyan, AM; Kogan, IY; Krapivin, MI; Kuznetzova, TV; Pendina, AA; Shilnikova, EM; Tikhonov, AV | 1 |
| Godley, LA; Jeff-Eke, M; Litwin, E; Mariani, CJ; Moen, EL; Nikitas, JN; Zullow, H | 1 |
| Gao, F; Huang, J; Lin, Z; Liu, W; Liu, X; Luo, H; Ou, Y; Wang, J; Wen, B; Xia, Y; Zhang, X; Zhou, B | 1 |
| Ehrlich, KC; Ehrlich, M | 1 |
| Anderton, SM; Drake, AJ; Kay, O; Konkel, JE; Leech, MD; McPherson, RC; Meehan, RR; Ottaviano, R; Prendergast, CT; Sweenie, CH; Thomson, JP; Wraith, DC; Zandee, SE | 1 |
| Lu, M; Mo, J; Wang, H; Yin, R | 1 |
| Batke, S; Kubik, G; Summerer, D | 1 |
| Frieler, CE; Moehlig, AR; Rodgers, MT; Yang, B | 1 |
| Jangiam, W; Rithidech, KN; Tungjai, M | 1 |
| Jansen, JH; Kroeze, LI; van der Reijden, BA | 1 |
| Davie, JR; Liyanage, VR; Rastegar, M; Zachariah, RM | 1 |
| Carvalho, AT; Gouveia, L; Kamerlin, SC; Kanna, CR; Platts, JA; Wärmländer, SK | 1 |
| Banerjee, S; Brooks, S; Egli, M; Eichman, BF; Joachimiak, A; Nocek, B; Pallan, PS; Stone, MP; Szulik, MW; Voehler, M | 1 |
| Borgaro, JG; Corrêa, IR; Dai, N; Guan, S; Quimby, A; Sun, D; Sun, Z; Zheng, Y; Zhu, Z | 1 |
| Lei, X; Lv, Q; Yin, X; Zhang, B; Zheng, T | 1 |
| Anderton, SM; Benson, M; Cruickshanks, HA; Dunican, DS; Lentini, A; McPherson, RC; Meehan, RR; Mjoseng, HK; Nestor, CE; Ottaviano, R; Pennings, S; Reinhardt, D; Thomson, JP | 1 |
| Karplus, K; Schreiber, J | 1 |
| Hua, J; Li, N; Mu, H; Tang, F; Wu, J; Zheng, L; Zhu, H | 1 |
| Bachman, M; Balasubramanian, S; Huber, SM; Mendil, L; Miska, EA; Smollett, K; van Delft, P; Werner, F | 1 |
| Kobayashi, Y; Nohara, K; Okamura, K; Sano, T; Takumi, S; Yanagisawa, H | 1 |
| Arakawa, T; Hori, M; Kimura, T; Nakamura, T; Nakano, T; Nakashima, H; Nakatani, T; Oda, M; Sekita, Y; Yamagata, K | 1 |
| Cui, L; Shao, F; Wu, Q; Xuan, S; Zhang, D | 1 |
| Bachman, M; Balasubramanian, S; Beck, S; Beraldi, D; Field, SF; Stewart, SK | 1 |
| Yuan, BF | 1 |
| Hatanaka, Y; Inoue, H; Inoue, K; Kamimura, S; Kurotaki, YK; Ogonuki, N; Ogura, A; Oikawa, M | 1 |
| Ghanbarian, AT; Hurst, LD | 1 |
| Alisch, RS; Barrett-Wilt, GA; Cengiz, P; Kintner, DB; Li, S; Papale, LA; Sabat, G | 1 |
| Chen, YS; Chong, ZC; Jiao, J; Li, D; Sun, BF; Wang, XL; Wang, XX; Zhao, Y; Zhou, YM | 1 |
| Cahill, ME; Casaccia, P; Couroussé, T; Estey, D; Fan, G; Faull, KF; Feng, J; Ferguson, D; Huynh, J; Jin, P; Kennedy, P; Koo, JW; Labonte, B; Laitman, BM; Le, T; Li, Y; Mensah, I; Ming, GL; Nestler, EJ; Ribeiro, E; Shao, N; Shen, L; Song, H; Stockman, V; Szulwach, KE; Turecki, G; Vialou, V; Zhong, C | 1 |
| Cheng, Y; Jin, P; Wang, T; Xie, N | 1 |
| Golla, JP; Sathyanarayana, BK; Sayeed, SK; Vinson, C; Zhao, J | 1 |
| West, AE | 1 |
| Burgess, D; Eichten, SR; Greally, JM; Green, D; Hermanson, PJ; Jeddeloh, J; Li, Q; Patterson, N; Richmond, T; Rosenbaum, H; Springer, NM; Suzuki, M; Wendt, J | 1 |
| Cao, C; Chen, J; Cui, Z; Dai, Y; Guo, L; Jing, H; Lin, H; Ou, M; Sui, W; Sun, Y; Tan, Q; Xue, W; Yan, Q; Yang, M; Zou, T | 1 |
| Li, PL; Wang, TZ; Zhang, LY; Zhang, XC | 1 |
| Bitinaite, J; Cheng, X; Corrêa, IR; Dai, N; Fomenkov, AI; Guan, S; Noren, CJ; Pais, JE; Roberts, RJ; Saleh, L; Sun, Z; Tamanaha, E; Vaisvila, R; Zheng, Y | 1 |
| Biel, M; Carell, T; Eisen, D; Koch, S; Künzel, AF; Laube, SK; Michalakis, S; Mittermeier, N; Müller, M; Perera, A; Schulze, E; Splith, V; Steinbacher, J; Wagner, M | 1 |
| Bachman, M; Carroll, T; Colin, L; de Bony, EJ; Defrance, M; Delatte, B; Dunning, MJ; Fuks, F; Halim, S; Ibrahim, AE; Ito, Y; Krueger, F; Lynch, AG; Murrell, A; Silva, AL; Stark, R; Stojic, L; Ten Hoopen, R; Uribe-Lewis, S; Vowler, SL | 1 |
| Aifantis, I; Chen, T; Deng, Y; Dong, C; Ichiyama, K; Kim, BS; Ndiaye-Lobry, D; Tanaka, S; Tian, Q; Wang, X; Wei, L; Yan, X; Zheng, P; Zou, Y | 1 |
| Sehgal, M; Shukla, A; Singh, TR | 1 |
| Aifantis, I; Aranda-Orgilles, B; Bakogianni, S; Bhattacharyya, S; Cimmino, L; Dawlaty, MM; Geng, H; Jaenisch, R; King, B; Liu, C; Lobry, C; Mullenders, J; Ndiaye-Lobry, D; Shaknovich, R; Shen, S; Trimarchi, T; Verma, AK; Yap, YS; Yu, Y | 1 |
| Devi, G; Shao, F; Xu, B | 1 |
| Godley, LA; Vasanthakumar, A | 1 |
| Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A | 1 |
| Chavez, L; Choi, J; Etchegaray, JP; Gladden, A; Goren, A; Hochedlinger, K; Huang, Y; Kugel, S; Lienhard, M; Martinez-Pastor, B; Mostoslavsky, G; Mostoslavsky, R; Ramaswamy, S; Rao, A; Ross, KN; Silberman, DM; Sommer, CA; Walsh, RM | 1 |
| DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
| Ito, S; Kuraoka, I | 1 |
| Baccarelli, AA; Bertazzi, PA; Byun, HM; Chang, D; Chervona, Y; Díaz, A; Hou, L; Kang, CM; Koutrakis, P; McCracken, JP; Osorio-Yanez, C; Sanchez-Guerra, M; Schwartz, J; Wang, S; Zhang, W; Zhang, X; Zheng, Y; Zhong, J | 1 |
| Chan, WY; Chung, JP; Kong, GW; Lee, TL; Qian, Y; Tang, NL; Tu, J | 1 |
| Lagunavičius, A; Serva, S | 1 |
| Her, YF; Maher, LJ; Nelson-Holte, M | 1 |
| Kauneckaitė, K; Sasnauskas, G; Siksnys, V; Tamulaitiene, G; Zagorskaitė, E | 1 |
| Greiner, A; Guibourt, V; Kolck, G; Kraus, TF; Kretzschmar, HA; Schierl, K | 1 |
| Halder, S; Krishnan, Y; Lannes, L; Schwalbe, H | 1 |
| Baccarelli, AA; Cingolani, P; Land, S; Mercado-Garcia, A; Ruden, DM; Sen, A; Senut, MC; Tellez-Rojo, MM; Wright, RO | 1 |
| Etchegaray, JP; Mostoslavsky, R | 1 |
| Drake, AJ; Khulan, B; Menon, G; Piyasena, C; Reynolds, RM; Seckl, JR | 1 |
| Baba, H; Baba, Y; Harada, K; Ishimoto, T; Iwagami, S; Kosumi, K; Kurashige, J; Miyake, K; Miyamoto, Y; Murata, A; Nakao, M; Oda, S; Sakamoto, Y; Watanabe, M; Yamamoto, M; Yoshida, N | 1 |
| Bachman, M; Balasubramanian, S; Burgess, HE; Iurlaro, M; Murrell, A; Reik, W; Uribe-Lewis, S; Yang, X | 1 |
| Pan, F; Weeks, O; Xu, M; Yang, FC | 1 |
| Khan, HA; Sherwani, SI | 1 |
| Chen, L; Chong, J; Fu, XD; He, C; Li, H; Lu, X; Wang, D; Wang, L; Xiao, R; Xu, L; Zhou, Y | 1 |
| Chan, WY; Feng, B; Jiang, X; Lee, TL; Liao, J; Luk, AC; Lun Mak, KK; Ng, SH; Rennert, OM; Tu, J | 1 |
| Caiafa, P; Ciccarone, F; Valentini, E; Zampieri, M | 1 |
| Carell, T; Giese, A; Hackner, B; Kraus, TF; Kretzschmar, HA; Michalakis, S; Müller, M; Perera, A; Pfaffeneder, T; Steinbacher, J; Wagner, M | 1 |
| Hu, N; Qu, Y; Wu, W; Xu, H; Yang, J; Yin, ZQ; Zeng, Y | 1 |
| Chung, DH; Groom, J; He, C; Ji, L; Neumann, DA; Schmitz, RJ; Westpheling, J; Yu, M | 1 |
| Grosser, C; Grothaus, K; Horsthemke, B; Wagner, N | 1 |
| Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M | 1 |
| Minamizaki, T; Yoshiko, Y; Yoshioka, H | 1 |
| Cheng, H; Kong, L; Lan, F; Li, X; Lv, R; Zhu, L | 1 |
| Chen, L; He, Y; Jin, P; Kong, J; Li, J; Lin, L; Miao, Z; Sun, M; Xin, N; Xu, X | 1 |
| Burns, KH; Rodić, N; Sharma, R; Taube, JM; Zampella, J | 1 |
| Chang, HT; Chang, HY; Chen, CC; Chen, CH; Fu, TY; Ger, LP; Huang, JS; Huang, SF; Li, GC; Liou, HH; Pan, HW; Tsai, KW; Tseng, HH; Yeh, MH | 1 |
| Cairns, BR; Khoddami, V; Yerra, A | 1 |
| French, BA; French, SW; Li, J; Shen, H; Tillman, BC | 1 |
| Chen, TT; Dunwell, JM; Dunwell, TL; Hu, SN; Huang, ZY; Li, YL; Liu, S; Pfeifer, GP; Song, SH; Ullah, I; Wamaedeesa, R; Wang, XL; Wang, Y; Wu, YS | 1 |
| Abdelhay, E; Batalha, AB; Boulhosa, AM; Bueno, AP; Coutinho, DF; Fernandez, TS; Gutiyama, LM; Monte-Mór, BC; Pombo-de-Oliveira, MS; Rouxinol, ST; Vianna, DT; Zalcberg, IR | 1 |
| Bhagwat, AS; Guruge, TA; Siriwardena, SU | 1 |
| Ai, S; Jiang, W; Liu, F; Yang, Z; Yin, H; Zhou, Y | 1 |
| Benner, C; Chang, HT; Chen, CH; Chen, SF; Gascon, P; Ger, LP; Hishida, T; Izpisua Belmonte, JC; Jan, CI; Lin, YS; Ma, L; Montserrat, N; Nieh, S; Sancho-Martinez, I; Wu, MZ | 1 |
| Bernotiene, E; Daniunaite, K; Fleury-Cappellesso, S; Gordevicius, J; Jarmalaite, S; Misgirdaite, R; Serenaite, I; Unguryte, A | 1 |
| Cheng, X; Corrêa, IR; Dai, N; Hashimoto, H; Pais, JE; Zhang, X; Zheng, Y | 1 |
| Barreiro, LB; Chen, GG; Ernst, C; Gross, JA; Pacis, A; Turecki, G | 1 |
| Han, D; He, C; Jiang, X; Liu, M; Lu, X; Sun, Z; Xia, B; Xie, W; Yi, C; Yin, Q; Zeng, H; Zhou, A | 1 |
| Dang, S; He, N; Hou, P; Ji, M; Lu, R; Qui, Y; Shi, B; Sui, F; Yang, Q | 1 |
| Amato, NJ; Jiang, J; Li, L; Liu, S; Wang, Y; Wang, Z | 1 |
| Castaño, GO; Dopazo, H; Gianotti, TF; Martino, JS; Pirola, CJ; Rohr, C; Scian, R; Sookoian, S | 1 |
| Bhutani, N; Li, YH; Rath, M; Smeriglio, P; Taylor, SE; Wong, WH | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Levy, D; Liu, X; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V; Thomas, T | 1 |
| Barreiro, LB; Danckaert, A; Dumaine, A; Gicquel, B; Gilad, Y; Grenier, JC; Hansen, KD; He, C; Kobor, MS; Lambourne, J; Luca, F; MacIsaac, JL; Morin, AM; Pacis, A; Pai, A; Pastinen, T; Pique-Regi, R; Tailleux, L; Tung, J; Yotova, V; Yu, M | 1 |
| Iba, Y; Iwata, K; Kai, Y; Mio, Y | 1 |
| Fujimura, T; Hayashizaki, Y; Homma, Y; Inoue, S; Misawa, A; Suzuki, T; Takagi, K; Takahashi, S; Takayama, K; Urano, T | 1 |
| Chen, A; Magliocco, SM; Ranganathan, SV; Shen, F; Sheng, J; Valsangkar, VA; Wang, R | 1 |
| Blüher, M; Böttcher, Y; Dietrich, A; Keller, M; Rohde, K; Stumvoll, M | 1 |
| Alisch, RS; Chen, K; Keleş, S; Li, S; Papale, LA; Zhang, Q | 1 |
| Incarnato, D; Neri, F; Oliviero, S | 1 |
| Cook, M; Lee, JJ; Lian, CG; Mihm, MC; Murphy, GF; Wang, TJ; Xu, S; Zhan, Q | 1 |
| Choi, BY; Kang, GH; Kim, HJ; Kim, M; Kim, SY; Kim, YS; Kwon, OH; Lim, B; Park, JL; Seo, EH; Song, KS | 1 |
| Bayley, JP; Bovée, JV; Breuning, MH; Briaire-de Bruijn, IH; Cornelisse, CJ; de Graaff, MA; Devilee, P; Frizzell, N; Hoekstra, AS; Hogendoorn, PC; Korpershoek, E; Kunst, HP; Ras, C; Seifar, RM; Suijker, J; van Minderhout, I | 1 |
| Iatrou, A; Kenis, G; Lardenoije, R; Meuwissen, KPV; Rutten, BPF; Schmitz, C; Steinbusch, HWM; Vaessen, TSJ; van den Hove, DLA; van Hagen, BTJ | 1 |
| Guibourt, V; Kilinc, S; Kraus, TF; Kretzschmar, HA; Steinmaurer, M; Stieglitz, M | 1 |
| Deng, C; FitzGerald, PC; He, X; Ray, GJ; Stamatoyannopoulos, J; Syed, KS; Tillo, D; Vierstra, J; Vinson, C | 1 |
| Chen, J; Hart, RP; Herrup, K; Jiang, D; Li, J; Zhang, Y | 1 |
| Cheng, J; Cui, Q; Fang, D; Gong, W; He, C; Hou, H; Hu, L; Jiang, H; Li, J; Li, W; Li, Z; Liu, M; Lou, Z; Lu, J; Luo, C; Rao, Q; Sun, C; Tan, X; Wang, P; Wang, Y; Xu, Y; Yang, P; Yin, X; Zhang, L | 1 |
| Barry, WT; Beroukhim, R; Birkbak, NJ; Clark, AP; Culhane, AC; Eklund, AC; Hill, DE; Landini, S; Lim, E; Neupane, M; Schumacher, SE; Silver, DP; Szallasi, Z; Vidal, M | 1 |
| An, J; Han, JA; Ko, M | 1 |
| Feng, YQ; Qi, BL; Xiong, J; Yuan, BF; Zhang, HY | 1 |
| Bassani, DM; Bullen, GA; Duprey, JL; Peacock, AF; Tucker, JH; Wilkie, J; Zhao, ZY | 1 |
| Fukuzawa, S; Suetake, I; Tachibana, K; Tajima, S | 1 |
| Alisch, RS; Chen, L; Chopra, P; Jin, P; Keleş, S; Li, S; Madrid, A; Papale, LA; Zhang, Q | 1 |
| Bissonnette, MB; Butun, F; Chapman, CG; Chuang, A; Godley, LA; Kwon, JH; Madzo, J; Mariani, CJ; Meckel, K; Wu, F | 1 |
| Gackowski, D; Modrzejewska, M; Olinski, R; Starczak, M; Zarakowska, E | 1 |
| Chen, K; Ci, W; Guo, Z; He, C; Ke, Y; Li, X; Li, Z; Liu, J; Liu, Y; Ma, Q; Xu, Z; Ye, X; Yuan, B; Zhang, J; Zhou, L; Zhou, Y | 1 |
| Biagini Myers, JM; Ji, H; Jurcak, N; Khurana Hershey, GK; Kovacic, MB; Ryan, PH; Somineni, HK; Ulm, A; Zhang, X | 1 |
| Chapman, VL; Dearman, RJ; Kimber, I; Moggs, JG; Terranova, R | 1 |
| Belle, KC; Belzil, VV; Benatar, M; Boylan, KB; Dickson, DW; Dykxhoorn, DM; Esanov, R; Petrucelli, L; Rademakers, R; van Blitterswijk, M; Wahlestedt, C; Wuu, J; Zeier, Z | 1 |
| Amouroux, R; D'Souza, Z; Encheva, V; Hajkova, P; Hill, PW; Koseki, H; Kudo, NR; Matsuda, M; Nakagawa, S; Nakayama, M; Nashun, B; Ndjetehe, E; Sasaki, H; Shirane, K; Turp, A | 1 |
| Chen, HX; Nie, J; Yuan, F; Zhang, XH; Zhang, XX; Zhou, YL | 1 |
| Bezerra, SM; Chaux, A; Gonzalez Roibon, N; Haffner, MC; Karram, S; Munari, E; Nelson, WG; Netto, GJ; Taheri, D; Vaghasia, AM; Yegnasubramanian, S | 1 |
| Chung, TH; Kim, A; Sun, X; Tan, D | 1 |
| Awe, S; Bonvin, E; Brehm, A; Calonne, E; Collignon, E; Creppe, C; Defrance, M; Delatte, B; Deplus, R; Fuks, F; Gueydan, C; Hassabi, B; Kreher, J; Kruys, V; Limbach, PA; Minakhina, S; Ngoc, LV; Putmans, P; Soin, R; Steward, R; Wang, F; Wetzel, C | 1 |
| Messerschmidt, DM | 1 |
| Ghosh, S; Scaria, V; Sengupta, S | 1 |
| Carrillo de Santa Pau, E; Chung, HR; Juan, D; Marsili, S; Ochoa, D; Perner, J; Rico, D; Valencia, A; Vingron, M | 1 |
| Leitner, K; Marx, A; von Watzdorf, J | 1 |
| Nakarakanti, NK; Nivya, MA; Rajakumara, E; Satish, M | 1 |
| Carlton, PM; Hatada, I; Horii, T; Kafer, GR; Li, X; Suetake, I; Tajima, S | 1 |
| Chen, CD; Fu, X; Li, J; Li, Q; Li, X; Lin, W; Liu, Y; Wan, Y; Wang, Y; Wang, Z; Xu, Y; Yan, Q; Ye, J; Zhang, F; Zhang, J; Zhang, L; Zhang, M; Zhang, X; Zhang, Z | 1 |
| Bian, XW; Chen, T; Dong, C; Ichiyama, K; Jin, W; Liu, X; Lu, H; Nallaparaju, KC; Tanaka, S; Tian, Q; Wei, L; Wen, X; Yan, X; Zhang, L; Zhang, X | 1 |
| Al-Sarraj, S; Burrage, J; Dempster, E; Hannon, E; Kepa, A; Lunnon, K; Mill, J; Schalkwyk, L; Smith, RG; Troakes, C; Wong, C | 1 |
| Choi, M; Jang, S; Jang, WY; Jeong, J; Kang, MC; Kim, H; Kim, MO; Kim, SH; Kwon, W; Park, S; Ryoo, ZY; Sung, Y | 1 |
| Äijö, T; Huang, Y; Lähdesmäki, H; Li, X; Lio, CW; Pastor, WA; Rao, A; Trifari, S; Tsagaratou, A; Vijayanand, P; Yue, X; Zepeda-Martínez, JA | 1 |
| Aksimentiev, A; Dai, Q; Ha, T; He, C; Ngo, TT; Yoo, J; Zhang, Q | 1 |
| Bianchessi, V; Capogrossi, MC; Farina, F; Gualdi, V; Lauri, A; Nigro, P; Pompilio, G; Rizzi, V; Vinci, MC | 1 |
| Creighton, CJ; Hawkins, SM; Loomans, HA; Roca, FJ; Wittman, AT | 1 |
| Li, J; Li, Q; Xu, Y; Zhang, F; Zhang, M; Zhang, Z | 1 |
| Cao, JL; Ding, HL; Hao, LY; Li, GF; Li, YQ; Ma, T; Pan, Z; Xue, ZY; Zhang, M; Zhu, LJ | 1 |
| Choi, JW; Cui, XS; Guo, J; Kim, NH; Liang, S; Lu, WF; Zhao, MH | 1 |
| He, Y; Jin, P; Tang, B; Wang, Z | 1 |
| Barazeghi, E; Dina, R; Gill, AJ; Hellman, P; Norlén, O; Palazzo, FF; Sidhu, S; Stålberg, P; Westin, G | 1 |
| Äijö, T; Chavez, L; Huang, Y; Lähdesmäki, H; Mannerström, H; Rao, A; Tsagaratou, A | 1 |
| Gershwin, ME; Li, D; Li, M; Liao, W; Lu, Q; Wang, J; Wu, H; Zhang, Y; Zhao, M | 1 |
| Fang, K; Fu, ZM; Wang, J; Zhang, KX; Zhao, XH | 1 |
| Avner, S; Guibert, S; Madigou, T; Mahé, EA; Salbert, G; Sérandour, AA; Weber, M | 1 |
| Brunger, AT; Diao, J; Quake, SR; Song, CX | 1 |
| Impey, S; Marzulla, T; Pelz, C; Raber, J; Tafessu, A; Turker, MS | 1 |
| Chen, Z; Feng, X; He, J; Luo, M; Shi, S; Shi, X; Yu, Y; Zhang, Z | 1 |
| Celarain, N; Echavarri, C; Larumbe, R; Mendioroz, M; Pulido, L; Roldán, M; Sánchez-Ruiz de Gordoa, J; Zelaya, MV | 1 |
| Marina, RJ; Oberdoerffer, S | 1 |
| Armstrong, DA; Christensen, BC; Green, BB; Guerin, DJ; Houseman, EA; Johnson, KC; Marsit, CJ | 1 |
| Korakavi, G; Kuang, H; Liu, Y; Lu, LY; Yu, X; Zhang, B | 1 |
| Christensen, BC; Houseman, EA; Johnson, KC | 1 |
| Wu, H; Wu, X; Zhang, Y | 1 |
| Incarnato, D; Krepelova, A; Neri, F; Oliviero, S; Parlato, C | 1 |
| Abbes, S; Bernard, OA; Cabagnols, X; Della Valle, V; Ishchenko, AA; Mahfoudhi, E; Plo, I; Rameau, P; Saparbaev, M; Secardin, L; Talhaoui, I; Vainchenker, W | 1 |
| Cantatore, S; DiNatale, A; Hennick, SM; Lazatin, JC; Mandarano, AH; Militello, KT; Simon, RD | 1 |
| Maunakea, AK; Pang, AP; Sugai, C | 1 |
| Fukuzawa, S; Suetake, I; Tachibana, K; Tajima, S; Takahashi, S | 1 |
| Chang, PM; Chou, NH; Kang, CH; Lam, HC; Li, GC; Liu, SI; Tsai, CY; Tsai, KW; Tu, YT; Wang, KC | 1 |
| Pfeifer, GP; Song, J | 1 |
| Devlieger, R; Duca, RC; Freson, K; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Straetmans, D; Van Herck, E | 1 |
| Abakir, A; Johnson, AD; Laurent, P; Ruzov, A; Wheldon, L | 1 |
| Äijö, T; Lähdesmäki, H; Rao, A; Yue, X | 1 |
| Li, Y; Ma, S; Qi, H; Sun, H; Zheng, J | 1 |
| Han, YW; Harada, Y; Kizaki, S; Li, Y; Sugiyama, H; Suzuki, Y; Zou, T | 1 |
| Agris, PF; Basanta-Sanchez, M; Huang, Y; Li, M; Liu, Z; Sheng, J; Shi, X; Wang, R; Ye, X; Zhou, Y | 1 |
| Coey, CT; Drohat, AC; Flowers, JW; Greenberg, MM; Pidugu, LS; Pozharski, E | 1 |
| Cheng, GJ; Hu, Y; Irudayaraj, J; Ouyang, L; Zhu, L | 1 |
| Shimbo, T; Wade, PA | 1 |
| Cheng, X; Hong, S | 1 |
| Foksinski, M; Gackowski, D; Gawronski, M; Modrzejewska, M; Olinski, R; Rzeszowska-Wolny, J; Skonieczna, M; Starczak, M; Zarakowska, E | 1 |
| Chau, YP; Cheng, JK; Ho, YC; Hsieh, MC; Lai, CY; Peng, HY; Wang, HH | 1 |
| Klungland, A; Robertson, AB | 1 |
| Chen, Z; Guo, L; He, J; Li, Y; Luo, M; Shi, X | 1 |
| Joo, SW; Kim, S; Nguyen, DB; Nguyen, TD | 1 |
| Zhang, H; Zuehlke, A | 1 |
| Li, C; Wang, F; Wang, H | 1 |
| David, M; Dursi, LJ; Simpson, JT; Timp, W; Workman, RE; Zuzarte, PC | 1 |
| Coyle, B; Lewis, L; Ramsawhook, A; Ruzov, A | 1 |
| Bronner, C; Dimitrov, S; Gras, SL; Hamiche, A; Ibrahim, A; Jost, B; Menoni, H; Papin, C; Stoll, I; Velt, A | 1 |
| Bieńkiewicz, A; Bryś, M; Ciesielski, P; Cwonda, Ł; Forma, E; Jóźwiak, P; Krześlak, A; Szczepaniec, S; Wójcik-Krowiranda, K | 1 |
| Cao, JL; Hao, LY; Li, GF; Pan, Z; Sun, ML; Tang, QQ; Xue, ZY; Zhang, M; Zhu, LJ | 1 |
| Cheng, QY; Feng, YQ; Liu, X; Xia, LX; Xiao, S; Xiong, J; Yuan, BF | 1 |
| Davis, AKF; DeNizio, JE; Kohli, RM; Nabel, CS; Schutsky, EK | 1 |
| Draghici, G; Nica, D; Popescu, C; Privistirescu, I; Stöger, R; Suciu, M | 1 |
| Fernández, AF; Fraga, MF; López, V | 1 |
| Moran, S | 1 |
| Behrens, MM; Bui, B; Castanon, R; Ecker, JR; Harkins, TT; He, Y; Keown, CL; Kurihara, L; Li, J; Lucero, J; Luo, C; Mukamel, EA; Nery, JR; Sandoval, JP; Sejnowski, TJ; Zhou, J | 1 |
| Chen, Y; Chua, MS; Diao, J; Dong, B; Hu, J; Jeffrey, SS; Li, W; Liu, B; Ma, L; Quake, SR; So, S; Song, CX; Tian, Z; Wei, Y; Wheeler, A; Xie, D; Xiong, J; Yin, S; Zhang, W; Zhang, Y; Zhou, Z | 1 |
| Ayata, P; Heintz, N; Mellén, M | 1 |
| Han, Q; Ji, S; Seiler, CL; Shao, H; Tretyakova, NY | 1 |
| Allgayer, J; Carell, T; Geier, N; Khobta, A; Kitsera, N; Parsa, E; Rossa, M | 1 |
| Banerjee, M; Nair, C; Nair, IV; Saradalekshmi, KR; Swathy, B | 1 |
| Brown, T; Hardwick, JS; Lane, AN | 1 |
| Cai, C; Chen, H; Feng, JJ; Yang, G; Yang, Y; Zhang, H | 1 |
| Alexeeva, M; Arshad, A; Bjelland, S; Bjørås, M; Gerasimaitė, R; Guragain, P; Klimašauskas, S; Klungland, A; Laerdahl, JK; Rukšėnaitė, A; Tesfahun, AN; Tomkuvienė, M; Urbanavičiūtė, G | 1 |
| Giehr, P; Kyriakopoulos, C; Lepikhov, K; Wallner, S; Walter, J; Wolf, V | 1 |
| Cao, D; He, Y; Jiang, J; Liu, D; Liu, J; Mo, J; Wang, H | 1 |
| Borre, M; Høyer, S; Lynnerup, AS; Storebjerg, TM; Strand, SH; Sørensen, KD; Ørntoft, TF | 1 |
| Manakova, E; Sasnauskas, G; Zagorskaitė, E | 1 |
| Ayon, NJ; Bhattacharya, C; Dey, AS; Gutheil, WG; Mukherji, M | 1 |
| Barekati, Z; Botev, P; Kuśnierczyk, A; Schär, P; Slupphaug, G; Steinacher, R | 1 |
| Blumenthal, RM; Cheng, X; Horton, JR; Huang, Y; Li, J; Ren, R; Sun, D; Wang, D; Yang, J; Zhang, X | 1 |
| Ci, W; Lu, H; Ma, Q; Xu, Z; Yuan, B; Zhou, Y | 1 |
| Cao, Z; Chen, Z; Gao, D; Khan, IM; Luo, L; Tong, X; Wang, Y; Xu, T; Zhang, D; Zhang, L; Zhang, M; Zhang, Y | 1 |
| Bewick, AJ; Grigoriev, IV; Hofmeister, BT; James, TY; Mondo, SJ; Powers, RA; Schmitz, RJ; Stajich, JE | 1 |
| Buchholz, F; Calegari, F; Noack, F; Pataskar, A; Schneider, M; Tiwari, VK | 1 |
| Wang, P; Yan, Y; Yu, W; Zhang, H | 1 |
| Chen, Y; Sugiyama, T | 1 |
| Bian, K; Chen, F; Drennan, CL; Essigmann, JM; Jost, M; Lenz, SAP; Li, D; Qi, R; Tang, Q; Wetmore, SD | 1 |
| Daumann, LJ; Jonasson, NSW | 1 |
| Kriegel, AJ; Liang, M; Liu, Y | 1 |
| Choi, JH; Lodh, A; Poole, CJ; van Riggelen, J | 1 |
| Cao, LL; Jia, M; Liu, H; Pei, L; Wang, H; Yue, Z | 1 |
| Hassan, HM; Torchia, J; Underhill, TM | 1 |
| Cai, C; Chen, D; Chen, J; Dai, Z; Liu, SY; Ma, Y; Mo, M; Wang, Y; Xu, Y; Zhang, J; Zhang, L; Zhang, Y; Zou, X | 1 |
| Argueta, C; Fetahu, IS; Liu, H; Ma, D; Rabidou, K; Shi, YG; Smith, M; Wu, F | 1 |
| Bochtler, M; Czapinska, H; Sasnauskas, G; Slyvka, A; Zagorskaitė, E | 1 |
| Abdelhamid, MAS; Ehiabor, MO; Grigg, MC; Irving, K; Smith, NM; Waller, ZAE; Wright, EP | 1 |
| Ananda, G; Bohec, M; Dedon, PC; Hammam, E; Preiser, PR; Scheidig-Benatar, C; Scherf, A; Sinha, A; Vembar, SS | 1 |
| Abakir, A; Fossdal, CG; Gackowski, D; Krutovsky, KV; Olinski, R; Ruzov, A; Starczak, M; Viejo, M; Yakovlev, IA | 1 |
| Aravind, L; Lio, CJ; Lopez-Moyado, IF; Rao, A; Tahiliani, M; Yue, X | 1 |
| Antes, I; Bauer, C; Cardoso, MC; Leonhardt, H; Schneider, M; Stengl, A; Szwagierczak, A; Trummer, C; Zhang, P | 1 |
| Del Rio-Tsonis, K; Fausey, A; Grajales-Esquivel, E; Kosse, S; Liang, C; Liu, L; Luz-Madrigal, A; Tangeman, J; Tsonis, PA; Wang, K | 1 |
| Biggiogera, M; Siciliani, S; Zannino, L | 1 |
| Fujii, S; Hirano, K; Kojima, N; Kurita, R; Namihira, M; Suda, T | 1 |
| Gackowski, D; Gawronski, M; Olinski, R; Starczak, M | 1 |
| Szabó, PE; Zeng, TB | 1 |
| Abakir, A; Ruzov, A | 1 |
| Trueman, RC; Wallis, MD | 1 |
| Gering, M; Jessop, P | 1 |
| Fossdal, CG; Viejo, M; Yakovlev, I | 1 |
| Celik-Uzuner, S | 1 |
| Gackowska, L; Gackowski, D; Labejszo, A | 1 |
| Abakir, A; Alenezi, F; Ruzov, A | 1 |
| Huang, Z; Kohli, RM; Meng, Y; Pfeifer, GP; Szabó, PE | 1 |
| Branco, MR; De Borre, M | 1 |
| Berrios, KN; Kohli, RM; Luo, M; Schutsky, EK; Wang, T; Wu, H | 1 |
| Buchmuller, B; Gieß, M; Muñoz-López, Á; Summerer, D | 1 |
| Edwards, JR; Singh, MK | 1 |
| Eltsov, IV; Nechipurenko, YD; Semyonov, DA | 1 |
| Assad, N; Durell, S; Ray, S; Tillo, D; Ufot, A; Vinson, C | 1 |
| Bochtler, M; Ikasalaitė, D; Jurkowski, TP; Klimašauskas, S; Ravichandran, M; Rukšėnaitė, A; Slyvka, A; Tomkuvienė, M | 1 |
| Bai, M; Cao, X; Chen, F; Fan, C; Su, L; Xue, J; Zhao, Y | 1 |
| Arensdorf, P; Beadell, AV; Bergamaschi, A; Bissonnette, M; Collin, F; Cui, XL; Deng, Z; Dougherty, U; Ellison, CK; Goel, A; He, C; Karpus, J; Ku, J; Levy, S; Nie, J; Ning, Y; Pekow, J; Sharma, G; Sieh, L; Talwar, R; Wei, J; West-Szymanski, DC; Zhang, W; Zhang, Z; Zhao, CWT | 1 |
| Akay, A; Braukmann, F; Helm, M; Hendrick, AG; Jordan, D; Kotter, A; Legrand, C; Lyko, F; Miska, EA; Navarro, IC; Price, J; Tuorto, F | 1 |
| Abhishek, S; Deeksha, W; Nakarakanti, NK; Rajakumara, E | 1 |
| Chen, S; Li, X; Liu, Y; Ma, Y; Sun, J; Wang, H; Zhang, N | 1 |
| Chen, W; He, C; He, L; Patil, SR; Zhang, J; Zhao, B | 1 |
| Guo, P; Lam, SL; Lee, HK; Wan, L; Yi, J | 1 |
| DeNizio, JE; Dow, BJ; Drohat, AC; Ghanty, U; Kohli, RM; Serrano, JC | 1 |
| Bachman, M; Bizet, M; Calonne, E; Colin, L; De Dieuleveult, M; Deplus, R; Fuks, F; Li, C; Miotto, B; Stancheva, I | 1 |
| Eden, HE; Huang, Z; Robertson, KD; Rothbart, SB; Tiedemann, RL | 1 |
| Ghanty, U; Kohli, RM; Serrano, JC | 1 |
| Chen, D; Dai, Z; Li, Y; Liu, SY; Xu, Y; Yu, Z; Zhang, Y; Zou, X | 1 |
| Bellacosa, A; Georges, RO; González-Avalos, E; Lio, CJ; Nakayama, T; Onodera, A; Rao, A | 1 |
| Anastasiadi, D; Fernandes, JMO; Konstantinidis, I; Mjelle, R; Nedoluzhko, AV; Piferrer, F; Podgorniak, T; Sætrom, P | 1 |
| Bronner, C; Dimitrov, S; Hamiche, A; Ibrahim, A; Klaholz, BP; Le Gras, S; Mohideen-Abdul, K; Papin, C; Stoll, I | 1 |
| Bai, L; Ding, C; Feng, J; Gong, T; Li, J; Li, X; Li, Z; Liu, M; Lyu, J; Qin, J; Qin, Z; Wang, Y; Yang, G; Yang, W | 1 |
| Beierlein, F; Imhof, P; Volkenandt, S | 1 |
| Lee, JY; Park, JW | 1 |
| Abreu, PL; Azzalin, CM; Caldas, P; de Almeida, MR; de Almeida, SF; Domingues, MM; Ferreira, AM; Grosso, AR; Sabino, JC; Santos, NC | 1 |
| Gibas, P; Godliauskaitė, E; Klimašauskas, S; Kriukienė, E; Kvederavičiūtė, K; Ličytė, J; Masevičius, V; Petraitytė, G; Rukšėnaitė, A; Tomkutė, V | 1 |
| Chapuis, C; D'Augustin, O; Huet, S; Lejart, A; Salbert, G; Smith, R; Zentout, S | 1 |
| Besaratinia, A; Caceres, A; Tommasi, S | 1 |
| Bu, L; Huang, J; Li, G; Luo, T; Yan, J | 1 |
| Ikasalaitė, D; Kairys, V; Klimašauskas, S; Manelytė, L; Meier, M; Tomkuvienė, M; Wildenauer, J | 1 |
| Asami, S; Matsui, T; Sakamoto, M; Taka, N; Yoshida, W | 1 |
| Breslin S J, P; Joshi, K; Liu, S; Zhang, J | 1 |
| Lin, TC; Palei, S; Summerer, D | 1 |
| Calvani, E; Capuano, F; Grayson, N; Grüning, NM; Messner, CB; Mülleder, M; Ralser, M; Varma, SJ | 1 |
| Bartke, T; Bultmann, S; Cheng, Y; Elsässer, SJ; Enard, W; Leonhardt, H; Mantero, AS; Mulholland, CB; Schneider, R; Stolz, P; Tvardovskiy, A; Ugur, E; Wange, LE; Wierer, M | 1 |
| Dai, HQ; Liu, W; Ruan, D; Shao, R; Shen, W; Wang, L; Xu, GL; You, X; Zou, W | 1 |
| Arroyo, M; Cardoso, MC; Carell, T; Hastert, FD; Ludwig, AK; Rausch, C; Schelter, F; Zhadan, A; Zimbelmann, S | 1 |
| Avila-Barnard, S; Volz, DC | 1 |
| Cao, W; Chang, C; Fang, GC; Li, J; Liang, C; Park, SH; Yang, Y | 1 |
| Balaiah, M; Mani, S; Ramasamy, D; Rao, AKDM; Sundersingh, S; Thangarajan, R; Veluswami, S; Vittal Rangan, A | 1 |
| Chen, KK; Feng, YQ; Ji, TT; Tang, F; Xie, C; Xie, NB; Xiong, J; Yu, SY; Yuan, BF | 1 |
| Hu, L; Xu, Y; Yin, X | 1 |
| Cheng, X; Hong, S; Horton, JR; Ren, R | 1 |
| Chen, XF; Dai, L; Dong, HL; Li, XL; Tan, ZJ; Wu, WQ; Yang, HY; Zhang, XH; Zhao, XC | 1 |
| Cheng, X; Du, Y; Gu, C; Guo, F; Long, X; Qian, J; Sun, F; Wang, H; Xu, Y; Yan, R; Zhai, J | 1 |
| Chen, KK; Feng, YQ; Guo, X; Ji, TT; Tang, F; Wang, M; Xie, C; Xie, NB; Xiong, J; Yu, SY; Yuan, BF | 1 |
| Bai, X; Liao, X; Liggins, C; Liu, YM; Mao, J; Pan, L; Tchounwou, P; Wang, M; Wang, S | 1 |
| Arman, B; Fullston, T; McPherson, N; Penn, A; Zander-Fox, D | 1 |
| An, J; Ko, M | 1 |
| Achrem, M; Gackowski, D; Kalinka, A; Starczak, M; Stępień, E | 1 |
| Broers, JLV; Hopman, AHN; Moshi, JM; Ramaekers, FCS; Ummelen, M | 1 |
| Balasubramanian, S; Becker, SM; Melidis, L; Mortishire-Smith, BJ; Simeone, A | 1 |
| Dai, E; Dai, M; Feng, J; Jia, Y; Liu, Z; Ye, L; Zhang, H | 1 |
| Berríos, KN; DeNizio, JE; Downey, N; Dvorak, A; Fowler, JM; Gosal, WS; Kohli, RM; Liu, L; Loo, CE; Luo, M; Montermoso, S; Nasrallah, M; Pingul, BY; Schutsky, EK; Wang, T; Wu, H | 1 |
| Kundu, S; Manna, D; Pain, PK; Palit, D; Sarma, R | 1 |
| Brock, N; Halford, NG; Kaur, N; Nayakoti, S | 1 |
| Arvanitakis, Z; Bissonnette, MA; Cai, J; Cai, Q; Cheng, SY; Chiu, BC; Cui, X; He, C; Shi, Y; Wu, K; Zeng, C; Zhang, W; Zhang, X; Zhang, Z | 2 |
| Chen, J; Jia, M; Jin, P; Mei, Y; Pan, H; Wang, JN; Wang, X | 1 |
| Chuaephon, A; Intharah, T; Ngernpimai, S; Phanchai, W; Puangmali, T; Sakonsinsiri, C; Thanan, R; Thonghlueng, J; Wanna, Y; Wiratchawa, K; Wiwasuku, T | 1 |
| An, R; Bai, Y; Cao, Y; Fan, Y; Gu, Q; Peng, J; Ren, L; Song, L; Song, W; Xie, XS; Yuan, T; Zheng, Y | 1 |
170 review(s) available for 5-methylcytosine and cytosine
| Article | Year |
|---|---|
Methylation, mutation and cancer.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplasm; Female; Genes, p53; Genetic Diseases, Inborn; Humans; Male; Methylation; Mutation; Neoplasms; Neoplasms, Experimental; Vertebrates | 1992 |
A fragile understanding.
Topics: 5-Methylcytosine; Brain; Cytosine; Female; Fetal Diseases; Fragile X Syndrome; Gene Expression Regulation; Genetic Carrier Screening; Humans; Intellectual Disability; Male; Meiosis; Methylation; Models, Genetic; Organ Specificity; Prenatal Diagnosis; Repetitive Sequences, Nucleic Acid; X Chromosome | 1991 |
5-Methylcytosine as an endogenous mutagen in the p53 tumor suppressor gene.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Genes, p53; Humans; Mutagens; Mutation; Neoplasms | 1991 |
DNA methylation and chromatin structure.
Topics: 5-Methylcytosine; Chromatin; Cytosine; Dinucleoside Phosphates; DNA; DNA-Binding Proteins; Heterochromatin; Methylation; Nucleic Acid Conformation; Transcription, Genetic | 1991 |
Frequency of abnormal human haemoglobins caused by C----T transitions in CpG dinucleotides.
Topics: 5-Methylcytosine; Cytosine; Deamination; Gene Frequency; Globins; Hemoglobins, Abnormal; Humans; Mutation | 1990 |
Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; Deamination; DNA; DNA Repair; Humans; Methylation | 1990 |
Hypomethylation of DNA in the regulation of gene expression.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms | 1988 |
DNA hypomethylation and differentiation of Friend erythroleukemia cells.
Topics: 5-Methylcytosine; Acetamides; Cell Differentiation; Cell Line; Cytosine; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Homocysteine; Leukemia, Erythroblastic, Acute; Methylation | 1988 |
Methylation at dinucleotides other than CpG: implications for human maintenance methylation.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Replication; Humans; Methylation | 1988 |
Developmental expression and modification of genes.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Chromatin; Cytosine; Deoxyribonuclease I; DNA; Embryonic and Fetal Development; Gene Expression Regulation; Humans; Mammals; Methylation; Morphogenesis; Nucleic Acid Conformation; Phosphoenolpyruvate Carboxykinase (GTP); Protein Biosynthesis; Protein Conformation; Proteins | 1987 |
The Pvu II restriction-modification system: cloning, characterization and use in revealing an E. coli barrier to certain methylases or methylated DNAs.
Topics: 5-Methylcytosine; Cloning, Molecular; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Modification Methylases; DNA-Cytosine Methylases; Escherichia coli; Phenotype; Restriction Mapping; Transformation, Genetic | 1987 |
[Effect of 5-methylcytosine in DNA and 5-azacytosine on the expression of various genes in vertebrates].
Topics: 5-Methylcytosine; Animals; Chickens; Cytosine; Gene Expression Regulation; Genes, Regulator; Humans; In Vitro Techniques; Methylation; Methyltransferases; Mice; Oncogenes | 1985 |
DNA methylation in eukaryotes.
Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin | 1982 |
Eukaryotic DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Differentiation; Chromosome Mapping; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA Replication; Eukaryotic Cells; Gene Expression Regulation; Genes; Genes, Viral; Humans; Methylation; Models, Genetic; Mutation; Transcription, Genetic; Transformation, Genetic | 1983 |
5-methylcytosine, gene regulation, and cancer.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes | 1983 |
DNA modification, differentiation, and transformation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Carcinogens; Cell Differentiation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Fibroblasts; Humans; Methylation; Mice; Papio; Phenotype; Rats; Transformation, Genetic | 1983 |
5-Azacytidine, DNA methylation, and differentiation.
Topics: 5-Methylcytosine; Azacitidine; Cell Differentiation; Cytidine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dosage Compensation, Genetic; Female; Gene Expression Regulation; Genes, Viral; Methylation; Methyltransferases; Nucleic Acids; Phosphorylation; RNA, Transfer; X Chromosome | 1984 |
DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice | 1984 |
5-Methylcytosine in eukaryotic DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Replication; DNA Restriction Enzymes; Genes; Methylation; Pyrimidines; Species Specificity; Substrate Specificity; Transcription, Genetic | 1981 |
DNA methylation--a regulatory signal in eukaryotic gene expression.
Topics: 5-Methylcytosine; Adenoviridae; Animals; Bacteriophages; Base Sequence; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Gene Expression Regulation; Genes, Viral; Herpesviridae; Insect Viruses; Methylation; Polyomavirus; Retroviridae; Simian virus 40 | 1981 |
DNA methylation and gene activity.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Replication; DNA-Directed RNA Polymerases; Drosophila; Escherichia coli; Genes; Methylation; Nucleic Acid Conformation; Recombination, Genetic; Simplexvirus; Transcription, Genetic | 1983 |
ADP-ribosyl transferase, rearrangement of DNA, and cell differentiation.
Topics: 5-Methylcytosine; Adenosine Diphosphate Ribose; Animals; Cell Differentiation; Cell Nucleus; Cytosine; DNA; DNA Repair; DNA, Superhelical; Gene Expression Regulation; Humans; Muscles; NAD; Nucleic Acid Conformation; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; T-Lymphocytes; Translocation, Genetic; Trypanosoma; Xenopus laevis | 1983 |
5-Methylcytosine depletion during tumour development: an extension of the miscoding concept.
Topics: 5-Methylcytosine; Alkylation; Amino Acid Metabolism, Inborn Errors; Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Cytosine; DNA; DNA Repair; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Models, Genetic; Neoplasms; Oncogenes; Rats; Tyrosine; Vitamin B 6 Deficiency | 1983 |
Effects of DNA methylation on mismatch repair, mutagenesis, and recombination in Escherichia coli.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Bacterial; Escherichia coli; Methyltransferases; Mutation; Recombination, Genetic | 1984 |
Replicative DNA methylation in animals and higher plants.
Topics: 5-Methylcytosine; Age Factors; Animals; Base Sequence; Cell Cycle; Cell Differentiation; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Gene Expression Regulation; Methylation; Plants; Species Specificity | 1984 |
Enzymatic DNA methylation in higher eukaryotes.
Topics: 5-Methylcytosine; Animals; Base Sequence; Carcinogens; Cell Differentiation; Chromosomes; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Eukaryotic Cells; Humans; Methylation | 1980 |
Modified bases in bacteriophage DNAs.
Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Bacteriophages; Base Composition; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytosine; Deoxyribonucleases; DNA Replication; DNA, Viral; Nucleic Acid Conformation; Pentoxyl; Substrate Specificity; Templates, Genetic; Thymine; Transcription, Genetic; Uracil | 1980 |
[Methylation of DNA in eukaryotes. I. Methylated sequences and DNA methylases].
Topics: 5-Methylcytosine; Age Factors; Animals; Bacteria; Base Sequence; Cattle; Cricetinae; Cytosine; Dipodomys; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Female; Guinea Pigs; Humans; Methylation; Methyltransferases; Mice; Plants; Rabbits; Rats; Repetitive Sequences, Nucleic Acid; Species Specificity; Xenopus | 1980 |
[Possible control of gene expression by DNA methylation (author's transl)].
Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Methylation; Mice; Rats | 1981 |
DNA methylation and transgene silencing in Petunia hybrida.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Plant; Epistasis, Genetic; Gene Expression Regulation, Plant; Genes, Plant; Methylation; Plant Proteins; Plants, Genetically Modified; Species Specificity; Zea mays | 1995 |
Genetic and epigenetic inactivation of repetitive sequences in Neurospora crassa: RIP, DNA methylation, and quelling.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Fungal; Epistasis, Genetic; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Meiosis; Methylation; Multigene Family; Neurospora crassa; Point Mutation; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Reproduction, Asexual | 1995 |
MIP: an epigenetic gene silencing process in Ascobolus immersus.
Topics: 5-Methylcytosine; Ascomycota; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Fungal; Epistasis, Genetic; Fungal Proteins; Gene Conversion; Gene Expression Regulation, Fungal; Meiosis; Methylation; Models, Genetic; Repetitive Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1995 |
[Hypermethylation and inactivity of hepatitis C virus cDNA transgene in transgenic mice].
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA, Complementary; Gene Expression Regulation, Viral; Genes, Viral; Hepacivirus; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data | 1995 |
DNA methylation and mutation.
Topics: 5-Methylcytosine; Animals; Base Composition; Cytosine; Dinucleoside Phosphates; DNA; DNA Repair; Humans; Methylation; Mutation; Neoplasms | 1993 |
Mechanisms of genomic imprinting in mammals.
Topics: 5-Methylcytosine; Alleles; Animals; Crosses, Genetic; Cytosine; Dosage Compensation, Genetic; Embryo Transfer; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Male; Mammals; Methylation; Mice; Mice, Transgenic; Muridae; Parthenogenesis; Ribonucleoproteins, Small Nuclear | 1994 |
Functions for DNA methylation in vertebrates.
Topics: 5-Methylcytosine; Animals; Binding Sites; Biological Evolution; Cytosine; DNA; Genes, Regulator; Genome; Methylation; Transcription, Genetic; Vertebrates | 1993 |
DNA methylation and gene activity: towards the end of the debate?
Topics: 5-Methylcytosine; Animals; Cattle; Chromatin; Chromosomal Proteins, Non-Histone; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Gene Expression Regulation; Histone Deacetylases; Methyl-CpG-Binding Protein 2; Methylation; Models, Genetic; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Vertebrates | 1994 |
Sequencing 5-methylcytosine residues in genomic DNA.
Topics: 5-Methylcytosine; Base Sequence; Blotting, Southern; Cytosine; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Genome; Hydrazines; Methylation; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites | 1994 |
Genetic instability of plant tissue cultures: breakdown of normal controls.
Topics: 5-Methylcytosine; Culture Techniques; Cytosine; DNA; Methylation; Plant Cells; Plants; Point Mutation; Repetitive Sequences, Nucleic Acid | 1994 |
The flip side of DNA methylation.
Topics: 5-Methylcytosine; Bacterial Proteins; Binding Sites; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; Gene Expression Regulation; Methylation | 1994 |
Spontaneous mutations and fidelogens.
Topics: 5-Methylcytosine; Animals; Antimutagenic Agents; Apurinic Acid; Cytosine; DNA Repair; DNA Replication; Escherichia coli; Free Radicals; Humans; Mutation; Neoplasms; Recombination, Genetic; Saccharomyces cerevisiae | 1993 |
Mutagenesis and transgenic systems: perspective from the mutagen, N-ethyl-N-nitrosourea.
Topics: 5-Methylcytosine; Animals; Animals, Genetically Modified; Cytosine; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Humans; Mice; Mutagenesis; Species Specificity | 1993 |
5-Methylcytosine in genes with methylation-dependent regulation.
Topics: 5-Methylcytosine; Cytosine; Gene Expression Regulation; Humans; Methylation; Transcription, Genetic | 1993 |
DNA methylation and retrovirus expression.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; Dinucleoside Phosphates; DNA; DNA Probes; DNA Restriction Enzymes; DNA, Viral; HIV; HIV Long Terminal Repeat; Humans; Mammals; Methylation; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phylogeny; Repetitive Sequences, Nucleic Acid; Retroviridae; Transcription, Genetic; Virus Replication | 1993 |
The repair of 5-methylcytosine deamination damage.
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cell Line; Cytosine; Deamination; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Escherichia coli; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Simian virus 40 | 1993 |
A chronicle of DNA methylation (1948-1975).
Topics: 5-Methylcytosine; Adenine; Animals; Cytosine; DNA; DNA, Recombinant; History, 20th Century; Methylation; Restriction Mapping | 1993 |
Methylation of cytosine influences the DNA structure.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Cytosine; DNA; Methylation; Models, Structural; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1993 |
DNA methylation and cancer.
Topics: 5-Methylcytosine; Animals; Cytosine; Dinucleoside Phosphates; DNA; DNA Repair; Genes, p53; Genes, Tumor Suppressor; Humans; Methylation; Mutagens; Mutation; Neoplasms; Transcription, Genetic | 1993 |
Effects of DNA methylation on DNA-binding proteins and gene expression.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Base Sequence; Consensus Sequence; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Gene Expression Regulation; Humans; Methylation; Models, Genetic; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Transcription Factors; Transcription, Genetic | 1993 |
Prevention of DNA 5-methylcytosine reutilization in human cells.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; DNA; Gene Expression Regulation; Homeostasis; Humans; Methylation; Models, Biological; Plants; S-Adenosylmethionine; Transcription, Genetic | 1995 |
The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene.
Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Genes, p53; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53 | 1996 |
DNA methylation and polyamines in embryonic development and cancer.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Humans; Male; Methylation; Mice; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Oogenesis; Polyamines; Replication Origin; Spermatogenesis; Transcription, Genetic | 1995 |
DNA methylation errors and cancer.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Imprinting, Psychological; Methylation; Mutation; Neoplasms | 1996 |
Mechanisms of spontaneous human cancers.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; Disease Susceptibility; DNA Damage; Environmental Exposure; Humans; Mutation; Neoplasms; Oxidation-Reduction; Risk Factors; Smoking | 1996 |
Sequencing 5-methylcytosine residues by the bisulphite method.
Topics: 5-Methylcytosine; Animals; Automation; Base Sequence; Cytosine; DNA; Indicators and Reagents; Nucleic Acid Denaturation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Sulfites | 1996 |
The relationship of DNA methylation to cancer.
Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms | 1996 |
Mutagenic and epigenetic effects of DNA methylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Enzymes; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Mutation; Neoplasms; Transcription, Genetic; Uracil | 1997 |
Altered DNA methylation and genome instability: a new pathway to cancer?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Humans; Mice; Neoplasms; Promoter Regions, Genetic | 1997 |
DNA methylation and the association between genetic and epigenetic changes: relation to carcinogenesis.
Topics: 5-Methylcytosine; Alkylating Agents; Animals; Cytosine; DNA Damage; DNA Methylation; DNA Modification Methylases; DNA Repair; Enzyme Inhibitors; Humans; Mutation; Neoplasms; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Topoisomerase II Inhibitors | 1997 |
Post-transcriptional gene silencing in plants.
Topics: 5-Methylcytosine; Cell Nucleus; Cytosine; Gene Expression Regulation, Plant; Plants; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Plant; Transgenes | 1997 |
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis.
Topics: 5-Methylcytosine; Alleles; Animals; Cell Differentiation; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Developmental; Humans; Mutation; Neoplasms; S-Adenosylmethionine | 1997 |
Oncogenic mechanisms mediated by DNA methylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Humans; Mammals; Mutation; Neoplasms; Nucleic Acid Conformation; Oncogenes | 1997 |
Mutagenesis in the P53 gene.
Topics: 5-Methylcytosine; Carcinogens, Environmental; Cytosine; DNA Damage; Genes, p53; Humans; Mutagens; Mutation; Neoplasms | 1997 |
Dynamic interrelationships between DNA replication, methylation, and repair.
Topics: 5-Methylcytosine; Animals; Chromatin; CpG Islands; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Repair; DNA Replication; DNA, Neoplasm; Gene Expression Regulation; Humans; Models, Genetic; Mutation; Neoplasm Proteins; Neoplasms; Proliferating Cell Nuclear Antigen; Tumor Suppressor Protein p53 | 1997 |
Mutational analyses of AVPR2 gene in three Japanese families with X-linked nephrogenic diabetes insipidus: two recurrent mutations, R137H and deltaV278, caused by the hypermutability at CpG dinucleotides.
Topics: 5-Methylcytosine; Amino Acid Substitution; Base Sequence; Cytosine; Diabetes Insipidus; DNA; DNA Mutational Analysis; Family Health; Female; Genetic Linkage; Humans; Japan; Male; Mutation; Point Mutation; Polymorphism, Single-Stranded Conformational; Receptors, Vasopressin; Sequence Deletion; X Chromosome | 1998 |
Identifying 5-methylcytosine and related modifications in DNA genomes.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Genome; Sensitivity and Specificity | 1998 |
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neoplasms; Cytosine; Deamination; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA Repair; Genes, p53; Humans; Lung Neoplasms; Mice; Mutagenesis; Neoplasms; Neoplasms, Radiation-Induced; Selection, Genetic; Skin Neoplasms; Smoking; Tumor Suppressor Protein p53; Ultraviolet Rays | 1998 |
Transition mutations at CpG dinucleotides are the most frequent in vivo spontaneous single-based substitution mutation in the human HPRT gene.
Topics: 5-Methylcytosine; Adult; Child; CpG Islands; Cytosine; DNA Mutational Analysis; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Lesch-Nyhan Syndrome; Male; Point Mutation | 1998 |
Principal causes of hot spots for cytosine to thymine mutations at sites of cytosine methylation in growing cells. A model, its experimental support and implications.
Topics: 5-Methylcytosine; Cell Division; Cytosine; DNA Damage; DNA Methylation; DNA Repair; DNA, Bacterial; Escherichia coli; Humans; Models, Genetic; Point Mutation; Replicon; Thymine | 1999 |
Identification of 5-methylcytosine in complex genomes.
Topics: 5-Methylcytosine; Cell Nucleus; Cytosine; DNA Methylation; Genome; Molecular Biology | 1999 |
DNA methylation: past, present and future directions.
Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Azacitidine; Carcinogens; Chromatin; Cytosine; DNA Methylation; DNA Repair; Forecasting; Gene Expression; Humans; Neoplasms | 2000 |
Mutation hotspots and DNA methylation.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; Genes, p53; Genes, Tumor Suppressor; Lung Neoplasms; Mutagenesis; Skin Neoplasms | 2000 |
Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation; Humans; Mice; Models, Genetic; Protein Binding | 2000 |
p53 mutational spectra and the role of methylated CpG sequences.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; DNA Repair; DNA, Neoplasm; Genes, p53; Humans; Lung Neoplasms; Mutation; Skin Neoplasms; Smoking; Sunlight | 2000 |
DNA methylation in ciliates: implications in differentiation processes.
Topics: 5-Methylcytosine; Adenine; Animals; Azacitidine; Cell Differentiation; Cell Nucleus; Ciliophora; Cytosine; DNA Methylation; DNA Modification Methylases; DNA, Protozoan; Gene Expression Regulation; Gene Expression Regulation, Developmental; Paramecium; Protozoan Proteins; Tetrahymena | 2000 |
Disease-causing mutations in the human genome.
Topics: 5-Methylcytosine; Cytosine; Databases, Factual; DNA; Gene Deletion; Genome, Human; Humans; Mutation | 2000 |
Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.
Topics: 5-Methylcytosine; Acetylation; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; CpG Islands; Cytosine; DNA Methylation; Fetal Hemoglobin; Gene Expression Regulation, Neoplastic; Hematologic Diseases; Histones; Humans; Methylation; Neoplasms | 2001 |
Methylation matters.
Topics: 5-Methylcytosine; Chromosome Aberrations; CpG Islands; Cytosine; DNA Methylation; DNA Transposable Elements; Gene Expression Regulation, Neoplastic; Genomics; Humans; Neoplasms; Oncogenes; Syndrome | 2001 |
DNA methylation and the regulation of gene transcription.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; DNA-Cytosine Methylases; Gene Silencing; Genetic Diseases, Inborn; Humans; Immunity; Mice; Models, Genetic; Transcription, Genetic | 2002 |
DNA methylation: a profile of methods and applications.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; Electrophoresis, Capillary; Genome; Microchemistry; Polymerase Chain Reaction; Restriction Mapping; Sequence Analysis, DNA; Sulfites | 2002 |
Cytosine methylation and DNA repair.
Topics: 5-Methylcytosine; Animals; Bacteria; CpG Islands; Cytosine; Dealkylation; Deamination; DNA Glycosylases; DNA Methylation; DNA Repair; DNA Replication; Humans; Mutagens; Neoplasms | 2006 |
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Cycle; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation; Humans | 2009 |
Genetic-epigenetic intersection in trophoblast differentiation: implications for extraembryonic tissue function.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation; Humans; Models, Biological; Models, Genetic; Placenta; Plants; Pregnancy; Stem Cells; Trophoblasts | 2010 |
Advances in DNA methylation: 5-hydroxymethylcytosine revisited.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; DNA; DNA Methylation; Genome; Hematologic Neoplasms; Humans; Oxygenases | 2011 |
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Histone Demethylases; Humans; Models, Biological; Oxidative Stress | 2011 |
5-Hydroxymethylcytosine, the sixth base of the genome.
Topics: 5-Methylcytosine; Animals; Bacteriophages; Cell Differentiation; Central Nervous System; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Female; Genome; Humans; Male; Mass Spectrometry; Neoplasms; Pluripotent Stem Cells | 2011 |
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond.
Topics: 5-Methylcytosine; Animals; Cell Cycle Proteins; Cytosine; Dioxygenases; DNA Methylation; DNA Repair; DNA-Binding Proteins; Humans; Mixed Function Oxygenases; Nuclear Proteins; Proto-Oncogene Proteins | 2011 |
Studying the epigenome using next generation sequencing.
Topics: 5-Methylcytosine; Animals; Base Composition; Cytosine; DNA; DNA Methylation; DNA, Intergenic; Epigenesis, Genetic; Epigenomics; Gene Expression; Genome; Genome-Wide Association Study; High-Throughput Nucleotide Sequencing; Histones; Humans; Mice; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Quantitative Trait Loci; Quantitative Trait, Heritable | 2011 |
The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.
Topics: 5-Methylcytosine; Adaptation, Physiological; Animals; Cytosine; Deamination; DNA; DNA Repair; Gene Expression Regulation; Genome; Genomics; Humans; Methylation; Mice; Mice, Knockout; Oxidation-Reduction; Polymorphism, Genetic | 2012 |
Uncovering the role of 5-hydroxymethylcytosine in the epigenome.
Topics: 5-Methylcytosine; Animals; Blastocyst Inner Cell Mass; Cell Differentiation; Cell Proliferation; Chromatin; CpG Islands; Cytosine; Deamination; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation, Developmental; Gene Silencing; Genome; Hematopoiesis; Humans; Mice; Mice, Knockout; Mixed Function Oxygenases; Proto-Oncogene Proteins; Tissue Distribution | 2011 |
Bisulfite methylation profiling of large genomes.
Topics: 5-Methylcytosine; Animals; Arabidopsis; Cytosine; DNA Methylation; Epigenesis, Genetic; Genome; High-Throughput Nucleotide Sequencing; Humans; Mice; Nanopores; Sulfites | 2010 |
Novel DNA binding domain-based assays for detection of methylated and nonmethylated DNA.
Topics: 5-Methylcytosine; Biomarkers; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Primers; Humans; Immunoprecipitation; Polymerase Chain Reaction; Protein Interaction Domains and Motifs; Sensitivity and Specificity; Sulfites | 2011 |
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Models, Biological; Oxidation-Reduction | 2011 |
DNA methylation: TET proteins-guardians of CpG islands?
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation; Humans; Mice; Proto-Oncogene Proteins; Transcription, Genetic | 2011 |
Hydroxylation mediates chromatin demethylation.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; DNA Methylation; Humans; Hydroxylation; Methylation | 2012 |
Dynamics of DNA methylation in aging and Alzheimer's disease.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; DNA; DNA Methylation; Humans; Neurodegenerative Diseases | 2012 |
Tet family proteins and 5-hydroxymethylcytosine in development and disease.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Epigenesis, Genetic; Humans; Mice; Mice, Knockout; Molecular Structure; Multigene Family; Neoplasms; Oxidation-Reduction; Protein Structure, Tertiary; Proto-Oncogene Proteins | 2012 |
Epigenetic features of the mouse trophoblast.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Histones; Mice; Models, Animal; Pregnancy; Pregnancy Complications; Trophoblasts | 2012 |
[Progress of research on 5-hydroxymethylcytosine].
Topics: 5-Methylcytosine; Animals; Cytosine; Epigenesis, Genetic; Humans | 2012 |
[Oxidation and deamination of nucleobases as an epigenetic tool].
Topics: 5-Methylcytosine; Animals; Base Composition; Chromatin Assembly and Disassembly; Cytosine; Deamination; DNA; DNA Methylation; DNA-Binding Proteins; Epigenomics; Gene Expression Regulation; Guanine; Mutation; Neoplasms; Oxidation-Reduction; Sequence Analysis, DNA; Transcription, Genetic | 2012 |
5-Hydroxymethylcytosine--the elusive epigenetic mark in mammalian DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Epigenesis, Genetic; Humans; Mammals | 2012 |
Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Humans; Neoplasms; Proto-Oncogene Proteins | 2013 |
[Recent advance in DNA epigenetic modifications-the sixth base in the genome].
Topics: 5-Methylcytosine; Animals; Biomarkers; Cell Differentiation; Cytosine; DNA; Epigenesis, Genetic; Gene Expression Regulation; Genome; Humans; Methylation | 2012 |
Nucleic acid modifications with epigenetic significance.
Topics: 5-Methylcytosine; Adenosine; Animals; Cytosine; DNA; Epigenesis, Genetic; Humans; Methylation; RNA | 2012 |
Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; Disease; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Genetic Markers; Humans; Restriction Mapping; Sequence Analysis, DNA | 2012 |
Epigenetic medicine and fetal alcohol spectrum disorders.
Topics: 5-Methylcytosine; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Gene Expression Regulation; Histones; Humans; Pregnancy | 2013 |
5-Hydroxymethylcytosine: generation, fate, and genomic distribution.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; Epigenesis, Genetic; Genome; Genome-Wide Association Study; Humans | 2013 |
DNA methylation and methylcytosine oxidation in cell fate decisions.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Chromatin Assembly and Disassembly; Cytosine; DNA Methylation; Epigenesis, Genetic; Genome; Histones; Humans; Oxidation-Reduction; Transcription Factors | 2013 |
Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mutation; Proto-Oncogene Proteins | 2013 |
Functions of DNA methylation and hydroxymethylation in mammalian development.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Embryonic Development; Gene Expression Regulation, Developmental; Genome; Humans; Mammals | 2013 |
Tet family of 5-methylcytosine dioxygenases in mammalian development.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Genome; Germ Cells; Humans; Proto-Oncogene Proteins | 2013 |
[Role of 5-hydroxymethylcytosine and TET proteins in epigenetic regulation of gene expression].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Hematopoiesis; Humans; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins | 2013 |
Cytosine modifications in neurodevelopment and diseases.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA-Cytosine Methylases; Humans; Models, Molecular; Nervous System Diseases; Neurogenesis | 2014 |
Epigenetic profiles as defined signatures of xenobiotic exposure.
Topics: 5-Methylcytosine; Animals; Carcinogens; Chemical Safety; Chromatin; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genetic Markers; Genome; Humans; Transcriptome; Xenobiotics | 2014 |
TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA Repair; Humans; Models, Biological; Mutagenesis; Neoplasms; Oxidation-Reduction | 2014 |
DNA modifications and neurological disorders.
Topics: 5-Methylcytosine; Brain; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Nervous System Diseases; Neurons | 2013 |
TET enzymes, TDG and the dynamics of DNA demethylation.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cellular Reprogramming; Cytosine; DNA Methylation; DNA Repair; DNA Replication; Humans; Neoplasms; Oxidation-Reduction; Thymine DNA Glycosylase | 2013 |
Investigating 5-hydroxymethylcytosine (5hmC): the state of the art.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA Methylation; Genetic Loci; Mammals; Molecular Biology; Molecular Sequence Data | 2014 |
5-hydroxymethylcytosine: a new insight into epigenetics in cancer.
Topics: 5-Methylcytosine; Animals; Brain Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Leukemia; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins | 2014 |
5-hydroxymethylcytosine profiling as an indicator of cellular state.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Models, Genetic; Neoplasms; Organ Specificity; Signal Transduction | 2013 |
Recent advances in the bioanalysis of modified nucleotides in epigenetic studies.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Nucleotides | 2013 |
[The world of double helix--"it did not escape our notice"].
Topics: 5-Methylcytosine; Base Sequence; Chromatin; Cytosine; DNA; DNA Repair; DNA, Catalytic; Epigenomics; Forecasting; Humans; Molecular Biology; Nanotechnology | 2013 |
Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders.
Topics: 5-Methylcytosine; Animals; Biological Evolution; Brain; Cytosine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mental Disorders; Models, Biological; Nerve Tissue Proteins; Neurogenesis; Neurons; Up-Regulation | 2014 |
5-hydroxymethylcytosine-mediated DNA demethylation in stem cells and development.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Humans; Stem Cells | 2014 |
Epigenetic modifications in the nervous system and their impact upon cognitive impairments.
Topics: 5-Methylcytosine; Acetylation; Animals; Central Nervous System; Cognition; Cognition Disorders; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Deacetylases; Histones; Humans; Learning; Memory; Models, Biological; Nerve Tissue Proteins; Neurons; Protein Processing, Post-Translational; Rett Syndrome; Rubinstein-Taybi Syndrome | 2014 |
The role of TET family proteins and 5-hydroxymethylcytosine in human tumors.
Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Neoplasms | 2014 |
The role of 5-hydroxymethylcytosine in human cancer.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Neoplasms; Oxidation-Reduction | 2014 |
Playing TETris with DNA modifications.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Signal Transduction | 2014 |
5-Hydroxymethylcytosine: A new player in brain disorders?
Topics: 5-Methylcytosine; Brain Diseases; Cytosine; Humans | 2015 |
Mechanism and function of oxidative reversal of DNA and RNA methylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Escherichia coli; Gene Expression Regulation; Genome; Germ Cells; HEK293 Cells; Humans; Methylation; Mice; Neoplasms; Oxygen; RNA; Stem Cells; Transcriptome | 2014 |
Mitoepigenetics and drug addiction.
Topics: 5-Methylcytosine; Amphetamines; Animals; Cocaine; Cytosine; DNA, Mitochondrial; Dose-Response Relationship, Drug; Epigenesis, Genetic; Ethanol; Gene Expression; Humans; Mitochondria; Morphine; Oxidative Stress; Substance-Related Disorders | 2014 |
New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enhancer Elements, Genetic; Hematopoiesis; Hematopoietic Stem Cells; Mice; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid | 2014 |
Connections between TET proteins and aberrant DNA modification in cancer.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries | 2014 |
DNA demethylation, Tet proteins and 5-hydroxymethylcytosine in epigenetic reprogramming: an emerging complex story.
Topics: 5-Methylcytosine; Animals; Cellular Reprogramming; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Induced Pluripotent Stem Cells; Models, Biological; Oxidation-Reduction | 2014 |
Loss of 5-hydroxymethylcytosine in cancer: cause or consequence?
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Humans; Mixed Function Oxygenases; Neoplasms; Oxidation-Reduction; Proto-Oncogene Proteins | 2014 |
5-Hydroxymethylcytosine: a stable or transient DNA modification?
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA Methylation; DNA Replication; DNA-Binding Proteins; Humans | 2014 |
TET enzymes and DNA hydroxymethylation in neural development and function - how critical are they?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Neurogenesis; Neurons; Oxidation-Reduction | 2014 |
From development to diseases: the role of 5hmC in brain.
Topics: 5-Methylcytosine; Aging; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Nervous System Diseases; Neurons | 2014 |
Genomic distribution and possible functions of DNA hydroxymethylation in the brain.
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Genome; Humans; Oxidation-Reduction | 2014 |
Expanding the epigenetic landscape: novel modifications of cytosine in genomic DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; Epigenesis, Genetic; Models, Genetic; Oxidation-Reduction | 2014 |
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Decidua; DNA Methylation; Embryo Implantation; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Humans; Pregnancy; Protein Processing, Post-Translational | 2014 |
5-hydroxymethylcytosine: a potential therapeutic target in cancer.
Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms | 2014 |
New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Ascorbic Acid; Cytosine; Diet; DNA Methylation; Folic Acid; Hematologic Neoplasms; Humans; MicroRNAs; Promoter Regions, Genetic; Structure-Activity Relationship; Transcription Factors | 2015 |
5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasms; Proto-Oncogene Proteins | 2015 |
5-methylcytosine and its derivatives.
Topics: 5-Methylcytosine; Chromatography, Thin Layer; Cytosine; DNA Methylation; Electrophoresis, Capillary; Endonucleases; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Humans; Microarray Analysis; Oxidation-Reduction; Polymerase Chain Reaction; Sulfites | 2014 |
DNA methylation and hydroxymethylation in stem cells.
Topics: 5-Methylcytosine; Adult; Animals; Cell Differentiation; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Stem Cells | 2015 |
Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Repair; Humans; Mental Disorders; Neoplasms; Neurodegenerative Diseases | 2015 |
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Humans; Isocitrate Dehydrogenase; Neoplasms; Proto-Oncogene Proteins | 2015 |
Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.
Topics: 5-Methylcytosine; Base Pair Mismatch; CpG Islands; Cytosine; Deamination; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Expression; Humans; Molecular Mimicry; Oxidation-Reduction; Thymine DNA Glycosylase | 2015 |
The TET2 interactors and their links to hematological malignancies.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Genes, Tumor Suppressor; Hematologic Neoplasms; Hematopoiesis; Humans; Mice; Mutation; Protein Interaction Maps; Proto-Oncogene Proteins | 2015 |
Role of 5-hydroxymethylcytosine in neurodegeneration.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Neurodegenerative Diseases | 2015 |
Functions of TET Proteins in Hematopoietic Transformation.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Genes, Tumor Suppressor; Hematologic Neoplasms; Hematopoiesis; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Oxidation-Reduction | 2015 |
Practical guidelines and consideration of using RRHP for 5hmC detection.
Topics: 5-Methylcytosine; Animals; Computational Biology; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Library; Guidelines as Topic; High-Throughput Nucleotide Sequencing; Humans | 2016 |
Hydroxymethyl cytosine marks in the human mitochondrial genome are dynamic in nature.
Topics: 5-Methylcytosine; Cytosine; DNA, Mitochondrial; Epigenesis, Genetic; Gene Expression Regulation; Genome, Mitochondrial; Humans | 2016 |
DNA methylation dynamics in neurogenesis.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Stem Cells; Epigenesis, Genetic; Histones; Humans; Mammals; Neurogenesis | 2016 |
[Advances on the profiling of 5-hydroxymethylcytosine].
Topics: 5-Methylcytosine; Animals; Cytosine; Epigenomics; High-Throughput Screening Assays; Humans | 2016 |
High-throughput sequencing offers new insights into 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; High-Throughput Nucleotide Sequencing; Humans; Organ Specificity | 2016 |
Are there specific readers of oxidized 5-methylcytosine bases?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA-Binding Proteins; Humans | 2016 |
Proteins That Read DNA Methylation.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Protein Domains | 2016 |
DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Eukaryota; Prokaryotic Cells; Protein Domains | 2016 |
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine.
Topics: 5-Methylcytosine; Animals; Carcinogenesis; Cell Self Renewal; Cytosine; DNA; DNA Methylation; DNA Repair; Humans; Oxidation-Reduction; Transcription, Genetic | 2017 |
Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Lymphatic Metastasis; Neoplasms; Prognosis | 2017 |
The role of 5-hydroxymethylcytosine in development, aging and age-related diseases.
Topics: 5-Methylcytosine; Aging; Animals; Cell Differentiation; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Oxidation-Reduction | 2017 |
Technologies for Deciphering Epigenomic DNA Patterns.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA Methylation; Epigenomics; Formaldehyde; Humans; Microarray Analysis; Paraffin Embedding; Sulfites; Tissue Fixation; Uracil | 2017 |
Epigenetic Modifications of Cytosine: Biophysical Properties, Regulation, and Function in Mammalian DNA.
Topics: 5-Methylcytosine; Animals; Crystallography, X-Ray; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Mammals; Models, Molecular; Nucleic Acid Conformation | 2018 |
Role of ten-eleven translocation proteins and 5-hydroxymethylcytosine in hepatocellular carcinoma.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Humans; Liver Neoplasms; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA Processing, Post-Transcriptional; Transcription, Genetic | 2019 |
TET methylcytosine oxidases: new insights from a decade of research.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Lineage; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA Replication; DNA-Binding Proteins; Embryonic Development; Humans; Oxidation-Reduction; S-Adenosylmethionine | 2020 |
DNA Hydroxymethylation in Smoking-Associated Cancers.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Mammals; Neoplasms; Proto-Oncogene Proteins; Smoking | 2022 |
Mechanisms that regulate the activities of TET proteins.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins | 2022 |
Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Hematologic Diseases; Humans; Mammals; Neoplasms | 2023 |
2 trial(s) available for 5-methylcytosine and cytosine
| Article | Year |
|---|---|
A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes.
Topics: 5-Methylcytosine; Adult; Aged; Binding Sites; Biopsy; Cardiovascular Diseases; Cohort Studies; Cytosine; DNA; DNA Methylation; Electrophoresis, Capillary; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Hydralazine; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; RNA, Untranslated; Uterine Cervical Neoplasms; Vasodilator Agents | 2005 |
Characterization of acute myeloid leukemia based on levels of global hydroxymethylation.
Topics: 5-Methylcytosine; Acute Disease; Adolescent; Adult; Aged; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Mutational Analysis; DNA-Binding Proteins; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins; Survival Analysis; Young Adult | 2014 |
1237 other study(ies) available for 5-methylcytosine and cytosine
| Article | Year |
|---|---|
Reaction of bisulfite with the 5-hydroxymethyl group in pyrimidines and in phage DNAs.
Topics: 5-Methylcytosine; Chemical Phenomena; Chemistry; Coliphages; Cytosine; DNA, Viral; Pentoxyl; Pyrimidines; Spectrophotometry, Ultraviolet; Sulfites; Uracil | 1979 |
Theoretical investigations on the conformation of 1,5,N(4),N(4)-tetramethylcytosine.
Topics: 5-Methylcytosine; Cytosine; Magnetic Resonance Spectroscopy; Molecular Conformation | 1978 |
Evidence for a near UV-induced photoproduct of 5-hydroxymethylcytosine in bacteriophage T4 that can be recognized by endonuclease V.
Topics: 5-Methylcytosine; Coliphages; Cytosine; DNA, Viral; Endonucleases; Substrate Specificity; Ultraviolet Rays | 1978 |
Modification and restriction of T-even bacteriophages. In vitro degradation of deoxyribonucleic acid containing 5-hydroxymethylctosine.
Topics: 5-Methylcytosine; Coliphages; Cytosine; DNA Restriction Enzymes; DNA, Circular; DNA, Viral; Escherichia coli; Genetic Complementation Test; Kinetics; Mutation; Phenotype; Species Specificity; Templates, Genetic | 1976 |
[Bacteriophage T2 DNA modification by O-methylhydroxylamine].
Topics: 5-Methylcytosine; Chemical Phenomena; Chemistry; Coliphages; Cytosine; DNA, Viral; Hydroxylamines; Nucleic Acid Denaturation; Viral Proteins | 1976 |
DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.
Topics: 5-Methylcytosine; Base Sequence; Cyclic AMP Receptor Protein; Cytosine; DNA, Bacterial; Escherichia coli; Methylation; Molecular Sequence Data; Mutation; Substrate Specificity; Thermodynamics; Thymine; Uracil | 1992 |
Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Central Nervous System; Cytosine; DNA; DNA Modification Methylases; Embryo, Mammalian; Immunohistochemistry; In Vitro Techniques; Microscopy, Electron; Proteins; Rats | 1992 |
A comparison of the fidelity of copying 5-methylcytosine and cytosine at a defined DNA template site.
Topics: 5-Methylcytosine; Animals; Avian Myeloblastosis Virus; Base Sequence; Cytosine; DNA; DNA Polymerase I; DNA Polymerase II; Drosophila melanogaster; Escherichia coli; Genes, Bacterial; Kinetics; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Templates, Genetic | 1992 |
The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Base Sequence; Chickens; Cytosine; DNA-Binding Proteins; Gene Expression Regulation; Histones; Macromolecular Substances; Methylation; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Oligodeoxyribonucleotides; Repressor Proteins; Structure-Activity Relationship; Vitellogenins | 1992 |
The photochemistry of 5-methylcytosine and 5-methyl-2'-deoxycytidine in aqueous solution.
Topics: 5-Methylcytosine; Antineoplastic Agents; Cytosine; Deoxycytidine; Photochemistry; Ultraviolet Rays | 1992 |
Large-scale methylation patterns in the nuclear genomes of plants.
Topics: 5-Methylcytosine; Cell Nucleus; Cytosine; DNA; Genome; Methylation; Plants | 1992 |
Cytosine methylation can induce local distortions in the structure of duplex DNA.
Topics: 5-Methylcytosine; Base Composition; Base Sequence; Cytosine; DNA; Electrophoresis, Polyacrylamide Gel; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1992 |
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Humans; Kininogens; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Promoter Regions, Genetic; Sulfites | 1992 |
DNA mismatch correction by Very Short Patch repair may have altered the abundance of oligonucleotides in the E. coli genome.
Topics: 5-Methylcytosine; Base Composition; Cytidine; Cytosine; DNA Repair; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Genome, Bacterial; Markov Chains; Mutation; Oligodeoxyribonucleotides; Saccharomyces cerevisiae; Thymidine | 1992 |
The distribution of 5-methylcytosine in the nuclear genome of plants.
Topics: 5-Methylcytosine; Base Composition; Chromatography, High Pressure Liquid; Cytosine; DNA; Fabaceae; Genome; Nicotiana; Plants, Medicinal; Plants, Toxic; Triticum; Zea mays | 1992 |
A sizing artifact of DNA restriction fragments with unusually long single-stranded termini.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA, Single-Stranded; DNA, Viral; Electrophoresis, Agar Gel; Mice; Simian virus 40; Single-Strand Specific DNA and RNA Endonucleases | 1991 |
Presence of 5-methylcytosine in CC(A/T)GG sequences (Dcm methylation) in DNAs from different bacteria.
Topics: 5-Methylcytosine; Bacteria; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Oligodeoxyribonucleotides | 1991 |
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Methylation; Phosphoglycerate Kinase; Regulatory Sequences, Nucleic Acid; Restriction Mapping; X Chromosome | 1990 |
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2.
Topics: 5-Methylcytosine; Base Sequence; Cloning, Molecular; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Dinucleoside Phosphates; DNA; DNA-Binding Proteins; Enkephalins; Gene Expression Regulation; Humans; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Protein Precursors; Restriction Mapping; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Dinucleoside Phosphates; Guanosine; Humans; Leukocytes; Male; Methylation; Molecular Sequence Data; Mutation; Oncogene Proteins; Phosphoproteins; Polymerase Chain Reaction; Receptors, LDL; Spermatozoa; Tumor Suppressor Protein p53 | 1990 |
Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: variable response to drug treatment and withdrawal.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Butyric Acid; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Dose-Response Relationship, Drug; HeLa Cells; Humans; Methylation; Tumor Cells, Cultured | 1990 |
Persistence of azacytidine-induced SCEs and genomic methylation in CHO cells in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Cycle; Chromatography, High Pressure Liquid; Cricetinae; Cytosine; In Vitro Techniques; Methylation; Sister Chromatid Exchange | 1990 |
Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; DNA; Kinetics; Methylation; Mice; Mice, Inbred C3H; Muscles; Oxygen | 1990 |
Characterization of chromosomes and localization of the rDNA locus in the aye-aye (Daubentonia madagascariensis).
Topics: 5-Methylcytosine; Animals; Chromosome Banding; Chromosome Mapping; Cytosine; DNA Restriction Enzymes; DNA, Ribosomal; Karyotyping; Male; Methylation; Silver; Staining and Labeling; Strepsirhini | 1990 |
Radioprotective properties of DNA methylation-disrupting agents.
Topics: 5-Methylcytosine; Animals; Azacitidine; Butyrates; Butyric Acid; Cell Survival; Cytosine; Depression, Chemical; DNA; In Vitro Techniques; Methylation; Radiation-Protective Agents; Stimulation, Chemical | 1991 |
Lack of 5-methylcytosine in Dictyostelium discoideum DNA.
Topics: 5-Methylcytosine; Actins; Base Sequence; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Dictyostelium; DNA, Fungal; Genes, Fungal; Restriction Mapping | 1991 |
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains | 1991 |
Biochemical mechanisms by which reutilization of DNA 5-methylcytosine is prevented in human cells.
Topics: 5-Methylcytosine; Cell Extracts; Cells, Cultured; Chromatography, Thin Layer; Cytosine; DCMP Deaminase; Deoxycytidine Monophosphate; DNA; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphocytes; Methylation; Nucleoside-Phosphate Kinase; Phosphorylation; Tetrahydrouridine; Tumor Cells, Cultured | 1991 |
Gene silencing in mammalian cells by direct incorporation of electroporated 5-methyl-2'-deoxycytidine 5'-triphosphate.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytosine; Deoxycytosine Nucleotides; Drug Resistance; Gene Expression Regulation; Methylation; Mutagenesis; Thioguanine | 1991 |
Nonrandom CpG mutations affect the synonymous codon usage of moderately GC-rich single copy actin genes.
Topics: 5-Methylcytosine; Actins; Animals; Codon; Cytosine; Fungi; Genes; Genes, Fungal; Giardia; Mutation; Species Specificity; Tetrahymena | 1991 |
A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methylt
Topics: 5-Methylcytosine; Cytosine; Escherichia coli; Guanine; Kinetics; Methylation; Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Ribosomal Proteins; Ribosomes; RNA, Ribosomal, 16S; Substrate Specificity | 1991 |
DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.
Topics: 5-Methylcytosine; Animals; Base Sequence; Binding Sites; Cattle; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Gene Expression Regulation, Viral; HIV Enhancer; HIV Long Terminal Repeat; HIV-1; Humans; Methylation; Models, Genetic; Molecular Sequence Data; NF-kappa B; Protein Binding; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Spleen; Transcription, Genetic | 1991 |
Spontaneous mutation at a 5-methylcytosine hotspot is prevented by very short patch (VSP) mismatch repair.
Topics: 5-Methylcytosine; Bacteriophage lambda; Base Sequence; Cytosine; DNA Mutational Analysis; DNA Repair; DNA, Bacterial; DNA, Viral; Escherichia coli; Methylation; Mutation | 1991 |
A novel activity in Escherichia coli K-12 that directs restriction of DNA modified at CG dinucleotides.
Topics: 5-Methylcytosine; Bacteriophage lambda; Cloning, Molecular; Cytosine; Dinucleoside Phosphates; DNA; DNA Restriction-Modification Enzymes; Escherichia coli; Mutation | 1991 |
DNA hypomethylation during liver cell proliferation induced by a single dose of lead nitrate.
Topics: 5-Methylcytosine; Animals; Cell Division; Cells, Cultured; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Lead; Liver; Male; Methylation; Mitogens; Nitrates; Organ Size; Rats; Rats, Wistar | 1991 |
Plasmodium falciparum: evidence for a DNA methylation pattern.
Topics: 5-Methylcytosine; Adenine; Animals; Base Composition; Base Sequence; Cytosine; Dinucleoside Phosphates; DNA Restriction Enzymes; DNA, Protozoan; Methylation; Plasmodium falciparum; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1991 |
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Damage; DNA Mutational Analysis; DNA-Cytosine Methylases; Female; Fetal Alcohol Spectrum Disorders; Gene Expression Regulation; Mice; Pregnancy | 1991 |
The restriction enzyme AlwNI is blocked by overlapping methylation.
Topics: 5-Methylcytosine; Adenosine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Base Sequence; Chromosome Deletion; Cloning, Molecular; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Mutational Analysis; Methylation; Molecular Sequence Data; Plasmids; Protein Precursors | 1991 |
5-Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmune rheumatic diseases.
Topics: 5-Methylcytosine; Adult; Autoimmune Diseases; Chromatography, High Pressure Liquid; Cyclosporine; Cytosine; DNA; Female; Humans; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; Rheumatic Diseases; Synovial Membrane | 1991 |
The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease.
Topics: 5-Methylcytosine; Base Composition; Base Sequence; beta-Lactamases; Cytosine; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Molecular Sequence Data; Recombinant Fusion Proteins; Thymine | 1991 |
Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study.
Topics: 5-Methylcytosine; Base Sequence; Calorimetry, Differential Scanning; Cytosine; DNA; Hydrogen-Ion Concentration; Molecular Sequence Data; Nucleic Acid Denaturation; Thermodynamics | 1991 |
Effects of cytosine methylation at restriction sites on deoxyribonucleic acid (DNA) typing.
Topics: 5-Methylcytosine; Blotting, Southern; Cytosine; DNA Fingerprinting; Humans; Methylation; Polymorphism, Restriction Fragment Length; Predictive Value of Tests | 1990 |
Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Dinucleoside Phosphates; DNA; DNA-Cytosine Methylases; Female; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Heteroduplexes | 1991 |
Analysis of 5-methylcytosine in DNA by isotope dilution gas chromatography-mass spectrometry.
Topics: 5-Methylcytosine; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Radioisotope Dilution Technique; Thymine | 1990 |
Stabilization of Z-DNA by demethylation of thymine bases: 1.3-A single-crystal structure of d(m5CGUAm5CG).
Topics: 5-Methylcytosine; Cytosine; DNA; Methylation; Models, Molecular; Nucleic Acid Conformation; X-Ray Diffraction | 1990 |
Interindividual concordance of methylation profiles in human genes for tumor necrosis factors alpha and beta.
Topics: 5-Methylcytosine; Cell Line; Cytosine; Genes; Granulocytes; Humans; Lymphotoxin-alpha; Methylation; Promoter Regions, Genetic; Restriction Mapping; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Genomic sequencing of the 5'-flanking region of the mouse beta-globin major gene in expressing and nonexpressing mouse cells.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; Cytosine; DNA, Neoplasm; Gene Expression; Genes; Globins; Leukemia, Erythroblastic, Acute; Mice; Molecular Sequence Data; Molecular Weight; Promoter Regions, Genetic; Restriction Mapping | 1990 |
Differential regulation of DNA methylation in rat testis and its regulation by gonadotropic hormones.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; Gonadotropins; Male; Methylation; Rats; Rats, Inbred Strains; Spermatogenesis; Testis | 1990 |
Effect of prolactin on DNA methylation in the liver and kidney of rat.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; Kidney; Liver; Methylation; Prolactin; Rats; Rats, Inbred Strains | 1990 |
[The effect of preparations of Hirudo medicinalis leeches on DNA methylation in the rat liver].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Fasting; Leeches; Liver; Methylation; Rats; Saliva; Time Factors; Tissue Extracts | 1990 |
Effect of 5-bromo- and 5-methyldeoxycytosine on duplex stability and discrimination of the NotI octadeoxynucleotide. Quantitative measurements using thin-layer chromatography.
Topics: 5-Methylcytosine; Base Sequence; Chromatography, Thin Layer; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA, Single-Stranded; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Plasmids; Templates, Genetic; Thermodynamics | 1990 |
Analysis of substrate specificity of the PaeR7 endonuclease: effect of base methylation on the kinetics of cleavage.
Topics: 5-Methylcytosine; Adenine; Animals; Base Sequence; Binding, Competitive; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Modification Methylases; Genes; Hydrogen-Ion Concentration; Kinetics; Methylation; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Substrate Specificity; Temperature | 1990 |
The accessibility of 5-methylcytosine to specific antibodies in double-stranded DNA of Xanthomonas phage XP12.
Topics: 5-Methylcytosine; Antibodies; Bacteriophages; Chemical Precipitation; Cytosine; DNA; DNA, Viral; Epitopes; Methylation; Microscopy, Electron; Nucleic Acid Conformation; Nucleic Acid Denaturation; Xanthomonas | 1985 |
DNA methylation at asymmetric sites is associated with numerous transition mutations.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Biological Evolution; Cytosine; DNA, Ribosomal; Methylation; Mutation; Neurospora crassa | 1985 |
[Isolation of modification-restriction enzymes HpaI and HpaII].
Topics: 5-Methylcytosine; Chromatography, Agarose; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Galactosides; Glycosides; Haemophilus; Hymecromone; Kinetics; Methylation; Methyltransferases; Sepharose; Site-Specific DNA-Methyltransferase (Adenine-Specific); Umbelliferones | 1985 |
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1986 |
Heterochromatin in the chromosomes of the gorilla: characterization with distamycin A/DAPI, D287/170, chromomycin A3, quinacrine, and 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cells, Cultured; Chromomycin A3; Chromosome Banding; Cytosine; Distamycins; DNA; Female; Fluorescent Dyes; Gorilla gorilla; Heterochromatin; Indoles; Lymphocytes; Male; Nucleolus Organizer Region; Primates; Quinacrine; Species Specificity; Staining and Labeling | 1986 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis | 1986 |
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation | 1986 |
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytosine; DNA; Fibroblasts; Humans; Methylation | 1987 |
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells.
Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabine; DNA, Neoplasm; Ethyl Methanesulfonate; Gene Expression Regulation; Lymphoma; Methylation; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Thy-1 Antigens | 1987 |
Methylation of Marek's disease virus DNA in chicken T-lymphoblastoid cell lines.
Topics: 5-Methylcytosine; Animals; Cell Line; Chickens; Cytosine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; DNA, Neoplasm; DNA, Viral; Herpesvirus 2, Gallid; Marek Disease; Methylation; T-Lymphocytes | 1987 |
DNA methylation pattern and restriction endonuclease accessibility in chromatin of a germ-line specific gene, the rainbow trout protamine gene.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; Erythrocytes; Gene Expression Regulation; Liver; Male; Methylation; Nucleotide Mapping; Organ Specificity; Protamines; Salmonidae; Spermatogenesis; Testis; Trout | 1987 |
Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.
Topics: 5-Methylcytosine; Albumins; alpha-Fetoproteins; Animals; Cell Line; Chromatin; Cytosine; Deoxyribonuclease I; DNA Restriction Enzymes; Gene Expression Regulation; Liver Neoplasms, Experimental; Methylation; Promoter Regions, Genetic; Rats; Transcription, Genetic | 1987 |
Sequence-dependence of the conformational changes induced by the 5-methyl cytosine in synthetic RNA oligomers.
Topics: 5-Methylcytosine; Cytosine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligoribonucleotides; RNA; Structure-Activity Relationship; Thermodynamics | 1987 |
Hypomethylation of DNA in pathological conditions of the human prostate.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA; Humans; Male; Mathematics; Methylation; Prostatic Hyperplasia; Prostatic Neoplasms | 1987 |
Time dependence of X gene reactivation induced by 5-azacytidine: possible progressive restructuring of chromatin.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Division; Cell Line; Chromatin; Cricetinae; Cytosine; Dosage Compensation, Genetic; Enzyme Induction; Female; Gene Expression Regulation; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylation | 1987 |
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice | 1987 |
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases | 1987 |
Changes in hepatic differentiation following treatment of rat fetuses with 5-azacytidine.
Topics: 5-Methylcytosine; alpha-Fetoproteins; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Hematopoiesis; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; RNA, Messenger; Tyrosine Transaminase | 1988 |
Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Clone Cells; Cytosine; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Phenotype; Triazenes | 1989 |
Gene structure and transcription in mouse cells with extensively demethylated DNA.
Topics: 5-Methylcytosine; Animals; Azacitidine; Chromatin; Clone Cells; Cytosine; Decitabine; DNA; Gene Expression Regulation; Methylation; Mice; Transcription, Genetic | 1989 |
Specific protection of methylated CpGs in mammalian nuclei.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chromatin; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; Dosage Compensation, Genetic; Methylation; Mice; Restriction Mapping | 1989 |
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors | 1989 |
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span.
Topics: 5-Methylcytosine; Azacitidine; Base Composition; Cell Division; Cell Transformation, Viral; Cytosine; Decitabine; DNA; Humans; In Vitro Techniques; Methylation; Simian virus 40 | 1989 |
DNA methylation and differentiation of human keratinocytes.
Topics: 5-Methylcytosine; Cell Differentiation; Cell Survival; Cells, Cultured; Cytosine; DNA; Gene Expression Regulation; Humans; In Vitro Techniques; Keratinocytes; Keratins; Methylation; Microscopy, Electron; Molecular Weight | 1989 |
Cleavage of DNA by HaeII is inhibited by the presence of 5-methylcytosine at the second cytosine within the recognition sequence.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA-Cytosine Methylases; DNA, Bacterial; Neisseria gonorrhoeae; Plasmids; Substrate Specificity | 1989 |
Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns.
Topics: 5-Methylcytosine; Adenovirus Early Proteins; Adenoviruses, Human; Animals; Base Sequence; Cell Line; Cell Transformation, Viral; Cricetinae; Cytosine; Gene Expression Regulation; Methylation; Oncogene Proteins, Viral; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid | 1989 |
Detection of 5-methylcytosine removal from DNA of Friend erythroleukemia cells following exposure to several differentiating agents.
Topics: 5-Methylcytosine; Acetamides; Animals; Cell Differentiation; Cytosine; Dimethyl Sulfoxide; DNA; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Niacinamide; Tumor Cells, Cultured | 1989 |
A different kind of inheritance.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Chromosomes; Cytosine; DNA; DNA Restriction Enzymes; Dosage Compensation, Genetic; Gene Expression Regulation; Genes, Switch; Genetics; Humans; Male; Methylation; Ovum; Spermatozoa | 1989 |
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; DNA-Binding Proteins; DNA, Recombinant; Metallothionein; Methylation; Mice; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Plasmids; Promoter Regions, Genetic; Structure-Activity Relationship; Transcription Factors | 1989 |
Induction of hepatitis B virus core gene in human cells by cytosine demethylation in the promoter.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Hepatitis B Core Antigens; Humans; Methylation; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Virus Replication | 1985 |
Modification of 5-methylcytosine in DNA and its relation to mutagenesis.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Methylation; Mutation; Oxidation-Reduction; Transfection | 1989 |
Identification of a second polypeptide required for McrB restriction of 5-methylcytosine-containing DNA in Escherichia coli K12.
Topics: 5-Methylcytosine; Cytosine; DNA Restriction-Modification Enzymes; DNA, Bacterial; Escherichia coli; Genetic Complementation Test; Phenotype; Plasmids | 1989 |
The UV excision-repair system of Saccharomyces cerevisiae is involved in the removal of methylcytosines formed in vivo by a cloned prokaryotic DNA methyltransferase.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Repair; DNA, Fungal; Methylation; Saccharomyces cerevisiae; Transformation, Genetic; Ultraviolet Rays | 1989 |
A simple high-resolution procedure to study DNA methylation and in vivo DNA-protein interactions on a single-copy gene level in higher eukaryotes.
Topics: 5-Methylcytosine; Animals; Chemical Phenomena; Chemistry; Chickens; Cytosine; DNA; DNA-Binding Proteins; Gene Amplification; Genes; Methylation; Piperidines; Promoter Regions, Genetic; Vitellogenins | 1989 |
Antitumour imidazotetrazines--XVIII. Modification of the level of 5-methylcytosine in DNA by 3-substituted imidazotetrazinones.
Topics: 5-Methylcytosine; Antineoplastic Agents; Cell Division; Cell Line; Cytosine; Dacarbazine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Humans; Imidazoles; Lymphocytes; Methylation; Temozolomide | 1989 |
Methylation of hen erythrocyte DNA.
Topics: 5-Methylcytosine; Animals; Chickens; Cytosine; DNA; Erythrocytes; Female; Leukocytes; Liver; Lung; Methylation; Methyltransferases; Mice; Spleen; Substrate Specificity | 1989 |
A plant DNA-binding protein that recognizes 5-methylcytosine residues.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cytosine; DNA; DNA-Binding Proteins; Methylation; Molecular Sequence Data; Plant Proteins; Plants | 1989 |
Differential hypomethylation of the c-myc protooncogene in bladder cancers at different stages and grades.
Topics: 5-Methylcytosine; Autoradiography; Blotting, Southern; Carcinoma, Transitional Cell; Cytosine; DNA, Neoplasm; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Staging; Oncogenes; Prognosis; Proto-Oncogene Mas; Proto-Oncogenes; Urinary Bladder Neoplasms | 1989 |
Ring-opening photoreactions of cytosine and 5-methylcytosine with aliphatic alcohols.
Topics: 5-Methylcytosine; Alcohols; Cytosine; Photolysis; Spectrophotometry, Ultraviolet; Ultraviolet Rays | 1989 |
Trace detection of modified DNA bases via moving-belt liquid chromatography-mass spectrometry using electrophoric derivatization and negative chemical ionization.
Topics: 5-Methylcytosine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytosine; DNA; Electrophoresis; Mass Spectrometry | 1989 |
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.
Topics: 5-Methylcytosine; Binding, Competitive; Cell Line; Cell Nucleus; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Probes; DNA-Binding Proteins; Gene Expression Regulation; Humans; Methylation; Molecular Weight; Structure-Activity Relationship | 1989 |
DNA-methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin and 3-deazaadenosine.
Topics: 5-Methylcytosine; Adenosine; Aminoglycosides; Anti-Bacterial Agents; Cell Count; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; Enzyme Inhibitors; Humans; Stereoisomerism; Tubercidin | 1989 |
Drug-induced DNA hypermethylation and drug resistance in human tumors.
Topics: 5-Methylcytosine; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytosine; DNA Replication; DNA, Neoplasm; Drug Resistance; Humans; Lung Neoplasms; Methylation; Rhabdomyosarcoma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Zidovudine | 1989 |
Phylogenetic evidence of a role for 5-hydroxymethyluracil-DNA glycosylase in the maintenance of 5-methylcytosine in DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Humans; Invertebrates; Phylogeny; Species Specificity; Vertebrates | 1989 |
Genomic sequencing and methylation analysis by ligation mediated PCR.
Topics: 5-Methylcytosine; Animals; Autoradiography; Base Sequence; Cytosine; DNA; Exons; HeLa Cells; Humans; Methylation; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Phosphoglycerate Kinase; Polymerase Chain Reaction; Promoter Regions, Genetic; X Chromosome | 1989 |
Cleavage of methylated CCCGGG sequences containing either N4-methylcytosine or 5-methylcytosine with MspI, HpaII, SmaI, XmaI and Cfr9I restriction endonucleases.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Restriction Enzymes; Nucleotide Mapping; Oligodeoxyribonucleotides; Substrate Specificity | 1987 |
Endonuclease from Acholeplasma laidlawii strain JA1 associated with in vivo restriction of DNA containing 5-methylcytosine.
Topics: 5-Methylcytosine; Acholeplasma laidlawii; Bacterial Proteins; Cytosine; DNA; DNA Restriction Enzymes; DNA, Bacterial; DNA, Circular; Substrate Specificity | 1987 |
Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Female; Humans; Male; Methylation; Molecular Sequence Data; Organ Specificity; Placenta; Spermatozoa | 1987 |
[A study on the role of DNA methylation within hCG and hPL genes in trophoblastic disease].
Topics: 5-Methylcytosine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Cytosine; DNA, Neoplasm; Female; Gene Expression Regulation; Humans; Methylation; Oncogenes; Placental Lactogen; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1987 |
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning.
Topics: 5-Methylcytosine; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; Escherichia coli; Phenotype; Species Specificity; T-Phages | 1988 |
Restriction analysis and quantitative estimation of methylated bases of filamentous and unicellular cyanobacterial DNAs.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Chromatography, High Pressure Liquid; Cyanobacteria; Cytosine; DNA; DNA Restriction Enzymes; Electrophoresis, Agar Gel; Genes; Methylation | 1988 |
Effect of cytosine methylation on cutting by the restriction enzyme MaeII.
Topics: 5-Methylcytosine; Bacteria; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; Substrate Specificity | 1988 |
BspMII and AccIII are an isoschizomer pair which differ in their sensitivity to cytosine methylation.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Substrate Specificity | 1988 |
Detection of heavy methylation in human repetitive DNA subsets by a monoclonal antibody against 5-methylcytosine.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Base Composition; Chromatography, Affinity; Cytosine; Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; DNA, Satellite; Electrophoresis, Agar Gel; Guanine; Immunoassay; Methylation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid | 1988 |
Determination of 5-methylcytosine in DNA by gas chromatography-electron-capture detection.
Topics: 5-Methylcytosine; Acylation; Alkylation; Chromatography, Gas; Chromatography, High Pressure Liquid; Cytosine; Detergents; DNA; Electrochemistry; Hydrolysis; Indicators and Reagents; Silicon Dioxide; Spectrophotometry, Ultraviolet | 1988 |
Distinct fractions of genomic DNA from cyanobacterium Nostoc commune that differ in the degree of methylation.
Topics: 5-Methylcytosine; Base Composition; Centrifugation, Density Gradient; Cyanobacteria; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Nucleic Acid Denaturation | 1988 |
Influence of streptozotocin upon the induction of tyrosine aminotransferase, the content of NAD and of 5-methyl cytosine in rat liver.
Topics: 5-Methylcytosine; Adrenalectomy; Animals; Cytosine; DNA; DNA Restriction Enzymes; Enzyme Induction; Liver; NAD; Rats; Rats, Inbred Strains; Streptozocin; Tyrosine Transaminase | 1986 |
Direct visualization of the sites of DNA methylation in human, and mosquito chromosomes.
Topics: 5-Methylcytosine; Aedes; Animals; Chromosome Banding; Chromosomes; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; Male; Methylation; Polymorphism, Restriction Fragment Length; Species Specificity | 1986 |
Methylated DNA-binding protein is present in various mammalian cell types.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cells, Cultured; Chromatography, Gel; Culicidae; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Electrophoresis, Agar Gel; Humans; Mice; Molecular Sequence Data; Nuclear Proteins; Placenta; Rats; Species Specificity | 1988 |
Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA.
Topics: 5-Methylcytosine; Adult; Aged; Aging; Cytosine; DNA; Genes; Humans; Lymphocytes; Methylation; Transcription, Genetic | 1989 |
DNA methylation in xeroderma pigmentosum.
Topics: 5-Methylcytosine; Cell Line; Cytosine; DNA; DNA Repair; HLA-DR Antigens; Humans; Methylation; Tetrahydrofolate Dehydrogenase; Xeroderma Pigmentosum | 1989 |
Til 1--a human lymphoblastoid cell line with minimal DNA methylation.
Topics: 5-Methylcytosine; Cell Line; Cytosine; DNA; Humans; Lymphocytes; Methylation; Nucleic Acid Hybridization | 1989 |
The effect of gamma radiation on DNA methylation.
Topics: 5-Methylcytosine; Animals; Cell Line; Cobalt Radioisotopes; Cytosine; DNA; DNA, Neoplasm; Gamma Rays; Humans; Methylation; Methyltransferases | 1989 |
Differential DNA methylation during the vegetative life cycle of Neurospora crassa.
Topics: 5-Methylcytosine; Cytosine; DNA, Fungal; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Methylation; Neurospora; Neurospora crassa | 1987 |
Mismatch repair of deaminated 5-methyl-cytosine.
Topics: 5-Methylcytosine; Bacteriophage lambda; Base Composition; Cytosine; DNA Repair; DNA, Bacterial; DNA, Viral; Escherichia coli; Genotype | 1987 |
Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites.
Topics: 5-Methylcytosine; Bacteriophage lambda; Base Sequence; Cytosine; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Genes, Viral; Mutation; Nucleic Acid Heteroduplexes | 1987 |
Determination of trace amounts of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography.
Topics: 5-Methylcytosine; Animals; Bacteriophage phi X 174; Bombyx; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA, Viral; Drosophila melanogaster; Hydrogen-Ion Concentration; Larva; Microchemistry; Pupa | 1987 |
Pattern of undermethylation of the major satellite DNA of mouse sperm.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chromatography, High Pressure Liquid; Cytosine; Deoxyribonucleosides; DNA Restriction Enzymes; DNA, Satellite; Hydrolysis; Male; Methylation; Mice; Organ Specificity; Spermatozoa | 1985 |
The chromatin structure of Rous sarcoma proviruses is changed by factors that act in trans in cell hybrids.
Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Cell Nucleus; Cell Transformation, Viral; Cells, Cultured; Chromatin; Cytosine; Deoxyribonuclease I; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Rats | 1985 |
Determination of DNA sequences containing methylcytosine in Bacillus subtilis Marburg.
Topics: 5-Methylcytosine; Bacillus subtilis; Base Sequence; Chromosomes, Bacterial; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA, Bacterial; Methylation | 1985 |
Structural organization of a hypermethylated nuclear DNA component in Physarum polycephalum.
Topics: 5-Methylcytosine; Base Composition; Chromatography, High Pressure Liquid; Cytosine; DNA Restriction Enzymes; DNA, Fungal; Electrophoresis, Agar Gel; Methylation; Nucleic Acid Hybridization; Physarum; Repetitive Sequences, Nucleic Acid | 1985 |
Investigation of restriction-modification enzymes from M. varians RFL19 with a new type of specificity toward modification of substrate.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Kinetics; Methylation; Micrococcus; Substrate Specificity | 1985 |
Analysis of products of DNA modification by methylases: a procedure for the determination of 5- and N4-methylcytosines in DNA.
Topics: 5-Methylcytosine; Chromatography; Cytosine; DNA; Electrophoresis; Hydrolysis; Methylation; Perchlorates | 1985 |
Developmental modulation of DNA methylation in the fungus Phycomyces blakesleeanus.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Fungal; DNA, Ribosomal; Genes, Fungal; Methylation; Mucorales; Nucleic Acid Hybridization; Phycomyces; Protein Biosynthesis | 1985 |
One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repair.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Chlorocebus aethiops; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Viral; Gene Expression Regulation; Kidney; Methylation; Models, Genetic; Simian virus 40 | 1985 |
Expression-linked demethylation of 5-methylcytosines in the chicken vitellogenin gene region.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chickens; Cytosine; DNA Restriction Enzymes; Female; Genes; Liver; Male; Methylation; Molecular Weight; Organ Specificity; Vitellogenins | 1985 |
Periodate-oxidized adenosine induction of murine thymidine kinase: role of DNA methylation in the generation of tumor cell heterogeneity.
Topics: 5-Methylcytosine; Adenosine; Animals; Cells, Cultured; Cytosine; DNA, Neoplasm; Enzyme Induction; Hydroxyurea; Methylation; Mice; Oxidation-Reduction; Periodic Acid; Thymidine Kinase | 1986 |
Mycoplasma restriction: identification of a new type of restriction specificity for DNA containing 5-methylcytosine.
Topics: 5-Methylcytosine; Acholeplasma laidlawii; Bacteriophages; Base Sequence; Chromosome Deletion; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; Methylation; Mutation; Transfection | 1986 |
[Chemical synthesis, isolation and sequencing of tetradecadeoxyribonucleotides containing the modified bases 5-fluorouracil and 5-methylcytosine].
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; Deoxyribonucleotides; DNA Restriction Enzymes; Fluorouracil; Nucleic Acid Heteroduplexes | 1985 |
Stage-specific DNA methylation in a fungal plant pathogen.
Topics: 5-Methylcytosine; Base Composition; Cell Division; Cytosine; DNA Restriction Enzymes; DNA, Fungal; Fungi; Methylation | 1986 |
A human DNA-binding protein is methylation-specific and sequence-specific.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cloning, Molecular; Cytosine; DNA-Binding Proteins; Endonucleases; Gene Expression Regulation; Humans; Methylation; Placenta; Single-Strand Specific DNA and RNA Endonucleases | 1986 |
DNA modification of a maize transposable element correlates with loss of activity.
Topics: 5-Methylcytosine; Alleles; Anthocyanins; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA Transposable Elements; Methylation; Phenotype; Plant Proteins; Zea mays | 1986 |
Escherichia coli K-12 restricts DNA containing 5-methylcytosine.
Topics: 5-Methylcytosine; Bacteriophage lambda; Base Sequence; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; Escherichia coli; Genes, Bacterial; Methyltransferases; Phenotype; Substrate Specificity | 1986 |
In-vivo-modified gonococcal plasmid pJD1. A model system for analysis of restriction enzyme sensitivity to DNA modifications.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Chromosomes, Bacterial; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; Neisseria gonorrhoeae; Plasmids | 1986 |
Synthesis of decadeoxyribonucleotides containing N6-methyladenine, N4-methylcytosine, and 5-methylcytosine: recognition and cleavage by restriction endonucleases (nucleosides and nucleotides part 74).
Topics: 5-Methylcytosine; Adenine; Circular Dichroism; Cytosine; DNA Restriction Enzymes; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Substrate Specificity | 1987 |
Localization of a genetic region involved in McrB restriction by Escherichia coli K-12.
Topics: 5-Methylcytosine; Bacterial Proteins; Cloning, Molecular; Cytosine; DNA; DNA Restriction Enzymes; Escherichia coli; Genes, Bacterial | 1987 |
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Precancerous Conditions; Recombination, Genetic; Virus Replication | 1987 |
Methylation of specific cytosine residues enhances simian virus 40 T-antigen binding to origin region DNA.
Topics: 5-Methylcytosine; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Base Sequence; Cytosine; DNA-Binding Proteins; DNA, Viral; Methylation; Oncogene Proteins, Viral; Protein Binding; Simian virus 40 | 1987 |
Site-specific methylases induce the SOS DNA repair response in Escherichia coli.
Topics: 5-Methylcytosine; Adenine; Bacteriophage lambda; Cloning, Molecular; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Repair; DNA Transposable Elements; Escherichia coli; Lysogeny; Methyltransferases; Mutation; Promoter Regions, Genetic; Site-Specific DNA-Methyltransferase (Adenine-Specific); SOS Response, Genetics | 1987 |
DNA mismatch-repair in Escherichia coli counteracting the hydrolytic deamination of 5-methyl-cytosine residues.
Topics: 5-Methylcytosine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Coliphages; Cytosine; DNA Repair; Escherichia coli; Genes; Genes, Bacterial; Hydrolysis; Mutation | 1987 |
The use of permanganate as a sequencing reagent for identification of 5-methylcytosine residues in DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Indicators and Reagents; Oligodeoxyribonucleotides; Oxidation-Reduction; Potassium Permanganate | 1987 |
Interaction of AluI, Cfr6I and PvuII restriction-modification enzymes with substrates containing either N4-methylcytosine or 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Bacterial; Methylation; Substrate Specificity | 1987 |
A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cell Line; Chlorocebus aethiops; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Recombinant; DNA, Viral; Guanine; Methylation; Simian virus 40; Thymine | 1987 |
Characterization of a unique methyl-specific restriction system in Streptomyces avermitilis.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA, Recombinant; Escherichia coli; Genetic Vectors; Methylation; Plasmids; R Factors; Restriction Mapping; Streptomyces | 1988 |
A simple method for locating methylated bases in DNA using class-IIS restriction enzymes.
Topics: 5-Methylcytosine; Adenine; Bacterial Proteins; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA-Cytosine Methylases; Genetic Techniques; Methylation; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity | 1988 |
In vivo methylation of yeast DNA by prokaryotic DNA methyltransferases.
Topics: 5-Methylcytosine; Adenine; Bacteriophages; Cytosine; DNA Ligases; DNA Repair; DNA-Cytosine Methylases; DNA, Fungal; Methylation; Methyltransferases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Site-Specific DNA-Methyltransferase (Adenine-Specific); Viral Proteins | 1988 |
Bacillus subtilis phage SPR codes for a DNA methyltransferase with triple sequence specificity.
Topics: 5-Methylcytosine; Bacillus subtilis; Bacteriophages; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; DNA, Viral; Methylation; Substrate Specificity; Viral Proteins | 1987 |
Reduced levels of histones H1o and H1b, and unaltered content of methylated DNA in rainbow trout hepatocellular carcinoma chromatin.
Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Chromatin; Cytosine; DNA; Histones; Liver; Liver Neoplasms, Experimental; Methylation; Transcription, Genetic; Trout; Vitellogenins | 1987 |
Photoexchange products of cytosine and 5-methylcytosine with N alpha-acetyl-L-lysine and L-lysine.
Topics: 5-Methylcytosine; Chemical Phenomena; Chemistry; Cytosine; Lysine; Magnetic Resonance Spectroscopy; Photochemistry; Spectrophotometry, Ultraviolet | 1988 |
A comparison between different types of covalent DNA modifications (I-compounds, persistent carcinogen adducts and 5-methylcytosine) in regenerating rat liver.
Topics: 2-Acetylaminofluorene; 5-Methylcytosine; Adenosine Triphosphate; Animals; Body Weight; Cytosine; DNA; Liver; Liver Regeneration; Male; Organ Size; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Localization, in human placenta, of the tightly bound form of DNA methylase in the higher order of chromatin organization.
Topics: 5-Methylcytosine; Chromatin; Chromatography, High Pressure Liquid; Cytosine; Deoxyribonuclease I; DNA; DNA (Cytosine-5-)-Methyltransferases; Electrophoresis; Female; Gas Chromatography-Mass Spectrometry; Humans; Placenta; Pregnancy; Proteins | 1988 |
Photochemical reactions of cytosine and 5-methylcytosine with methylamine and n-butylamine.
Topics: 5-Methylcytosine; Butylamines; Cytosine; Methylamines; Photochemistry; Ultraviolet Rays | 1988 |
[The effect of cytosine methylation in TTGGA(N5)TCCAA sequence of 5'-flanking region if the chicken betaH-globin gene on the interaction with TGGCA-binding protein in vitro].
Topics: 5-Methylcytosine; Animals; CCAAT-Enhancer-Binding Proteins; Chickens; Cytosine; Deoxyribonuclease BamHI; DNA; DNA-Binding Proteins; Globins; Methylation; NFI Transcription Factors; Nuclear Proteins; Nucleotide Mapping; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Transcription Factors; Y-Box-Binding Protein 1 | 1988 |
DNA methylation in plants.
Topics: 5-Methylcytosine; Cell Differentiation; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Gene Expression Regulation; Methylation; Plant Growth Regulators; Plant Proteins; Triticum | 1988 |
Cytosine methylation as an effector of right-handed to left-handed DNA structural transitions.
Topics: 5-Methylcytosine; Bacterial Proteins; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA-Cytosine Methylases; DNA, Bacterial; DNA, Recombinant; DNA, Superhelical; Methylation; Nucleic Acid Conformation; Plasmids | 1988 |
Cytosine methylation does not affect binding of transcription factor Sp1.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Humans; Metallothionein; Methylation; Promoter Regions, Genetic; Protein Binding; Sp1 Transcription Factor; Transcription Factors | 1988 |
The CpG dinucleotide and human genetic disease.
Topics: 5-Methylcytosine; Codon; Cytidine Monophosphate; Cytosine; Cytosine Nucleotides; Dinucleoside Phosphates; DNA; Genetic Diseases, Inborn; Guanosine; Humans; Methylation; Mutation | 1988 |
Reduced genomic 5-methylcytosine content in human colonic neoplasia.
Topics: 5-Methylcytosine; Adult; Aged; Colonic Neoplasms; Cytosine; DNA, Neoplasm; Gardner Syndrome; Humans; Methylation; Middle Aged | 1988 |
Biochemical effects of methyl chloride in relation to its tumorigenicity.
Topics: 5-Methylcytosine; Aldehyde Oxidoreductases; Animals; Cytosine; DNA Damage; Female; Formaldehyde; Glutathione Transferase; Kidney Neoplasms; Male; Methyl Chloride; Mice; Microsomes; Rats; Rats, Inbred F344; Sex Factors | 1988 |
5-Hydroxymethylcytosine DNA glycosylase activity in mammalian tissue.
Topics: 5-Methylcytosine; Animals; Cattle; Chromatography, High Pressure Liquid; Cytosine; DNA Glycosylases; DNA, Viral; N-Glycosyl Hydrolases; T-Phages; Thymus Gland | 1988 |
DNA methylation levels in acute human leukemia.
Topics: 5-Methylcytosine; Acute Disease; Cytosine; DNA, Neoplasm; Humans; Leukemia; Methylation | 1988 |
UV-induced photoproducts of 5-methylcytosine in a DNA sequence context.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chromatography, High Pressure Liquid; Coliphages; Cytosine; DNA Damage; DNA, Viral; Photochemistry; Pyrimidine Dimers; Rats; Ultraviolet Rays | 1988 |
[Effect of N4-methylcytosine and 5-methylcytosine on the stability of the DNA helix].
Topics: 5-Methylcytosine; Cytosine; Deoxyribonucleotides; DNA; Methylation; Nucleic Acid Conformation; Thermodynamics | 1988 |
Bovine thymus satellite I DNA sequences, which are highly methylated, are preferentially located in H1-rich chromatin.
Topics: 5-Methylcytosine; Animals; Cattle; Chromatin; Cytosine; DNA, Satellite; Histones; Methylation; Thymus Gland | 1988 |
Structural interconversion of alternating purine-pyrimidine inverted repeats cloned in supercoiled plasmids.
Topics: 5-Methylcytosine; Cytosine; Distamycins; DNA; DNA, Superhelical; Hydrogen Bonding; Methylation; Nucleic Acid Conformation; Plasmids; Repetitive Sequences, Nucleic Acid | 1988 |
[Effect of tamponade on the nucleotide composition and cytosine methylation level of DNA in the heart muscle of dogs].
Topics: 5-Methylcytosine; Acute Disease; Animals; Cardiac Tamponade; Cytosine; DNA; Dogs; Epinephrine; Male; Methylation; Myocardium; Nucleotides | 1987 |
Determination of 5-methylcytosine by acid hydrolysis of DNA with hydrofluoric acid.
Topics: 5-Methylcytosine; Animals; Base Composition; Chromatography, High Pressure Liquid; Cytosine; Deamination; DNA; Hydrofluoric Acid; Hydrolysis; Methylation | 1987 |
Antitumour imidazotetrazines-X. Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4-(3H)-one (CCRG 81045; M & B 39831; NSC 362856) on DNA methylation during induction of haemoglobin synthesis in human leukaemia cell line K562.
Topics: 5-Methylcytosine; Antineoplastic Agents; Cell Differentiation; Cell Line; Cytosine; Dacarbazine; DNA Replication; DNA, Neoplasm; Gene Expression Regulation; Globins; Hemoglobins; Humans; Imidazoles; Leukemia, Erythroblastic, Acute; Methylation; Temozolomide; Templates, Genetic; Time Factors | 1986 |
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.
Topics: 5-Methylcytosine; Acetamides; Animals; Base Sequence; Cell Differentiation; Cytosine; Dealkylation; Deoxycytidine; DNA; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Mice | 1986 |
Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis.
Topics: 5-Methylcytosine; Animals; Base Sequence; Binding Sites; Chickens; Cytosine; DNA; Female; Gene Expression Regulation; Kinetics; Liver; Male; Methylation; Oviducts; Receptors, Estrogen; Receptors, Glucocorticoid; RNA, Messenger; Vitellogenins | 1986 |
Naturally occurring methylation inhibitor: DNA hypomethylation and hemoglobin synthesis in human K562 cells.
Topics: 5-Methylcytosine; Cell Division; Cell Line; Cell Nucleus; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Erythropoiesis; Gene Expression Regulation; Genes; Globins; Hemin; Hemoglobins; Humans; Leukemia, Myeloid; Methylation; Peptides | 1987 |
DNA cytosine methylation and heat-induced deamination.
Topics: 5-Methylcytosine; Cytosine; Deamination; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Hot Temperature; Humans; Kinetics; Methylation; Thymine; Uracil | 1986 |
Distribution of 5-methylcytosine-rich regions in the polytene chromosomes of Phaseolus coccineus embryo suspensor as shown by the immunoperoxidase technique.
Topics: 5-Methylcytosine; Chromosomes; Cytosine; Fabaceae; Immunoenzyme Techniques; Nucleic Acid Hybridization; Plants, Medicinal | 1986 |
O6-methylguanine specifically induces AT----GC transition mutations.
Topics: 5-Methylcytosine; Adenine; Alkylation; Base Composition; Cytosine; DNA Damage; DNA, Bacterial; Escherichia coli; Guanine; Hypoxanthine; Hypoxanthines; Mutation | 1987 |
Reduced levels of DNA 5-methylcytosine in metastatic variants of the human melanoma cell line MeWo.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; Humans; Hydrolysis; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Uridine | 1987 |
The crystal structure of d(GGm5CCGGCC): the effect of methylation on A-DNA structure and stability.
Topics: 5-Methylcytosine; Cytosine; DNA; Methylation; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1987 |
[DNA methylation and interaction with glucocorticoid receptor complexes in the rat liver].
Topics: 5-Methylcytosine; Adrenalectomy; Aging; Animals; Cytosine; DNA; Female; Hydrocortisone; Liver; Methylation; Rats; Receptors, Glucocorticoid | 1987 |
Infection with frog virus 3 allows transcription of DNA methylated at cytosine but not adenine residues.
Topics: 5-Methylcytosine; Adenosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Recombinant; Gene Expression Regulation; Iridoviridae; Methylation; Promoter Regions, Genetic; RNA Polymerase II; Transcription, Genetic; Viral Proteins | 1987 |
Synthesis and physical characterization of DNA fragments containing N4-methylcytosine and 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Circular Dichroism; Cytosine; DNA; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides | 1987 |
Characterization of the genome of Arabidopsis thaliana.
Topics: 5-Methylcytosine; Chloroplasts; Cloning, Molecular; Cytosine; DNA; DNA, Ribosomal; Electrophoresis, Agar Gel; Genes; Methylation; Nucleic Acid Hybridization; Plants; Repetitive Sequences, Nucleic Acid | 1986 |
5-Methylcytosine levels in nucleosome subpopulations differently involved in gene expression.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Gene Expression Regulation; Kidney; Nucleosomes; Swine | 1986 |
Caenorhabditis elegans DNA does not contain 5-methylcytosine at any time during development or aging.
Topics: 5-Methylcytosine; Aging; Animals; Caenorhabditis; Chromatography, High Pressure Liquid; Crosses, Genetic; Cytosine; DNA; Nucleic Acid Hybridization; Species Specificity | 1986 |
[DNA-methylation: signal for gene regulation].
Topics: 5-Methylcytosine; Animals; Cytosine; Gene Expression Regulation; Humans; Methylation; S-Adenosylmethionine | 1986 |
Inheritance of DNA methylation in Coprinus cinereus.
Topics: 5-Methylcytosine; Agaricales; Coprinus; Crosses, Genetic; Cytosine; DNA, Fungal; Genetic Variation; Meiosis; Methylation | 1986 |
Reaction kinetics and cytosine adducts of chloroethylene oxide and chloroacetaldehyde: direct observation of intermediates by FTNMR and GC-MS.
Topics: 5-Methylcytosine; Acetaldehyde; Chemical Phenomena; Chemistry; Cytidine; Cytosine; DNA; DNA Damage; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Uridine | 1986 |
DNA methylation of bacterial viruses T3 and T7 by different DNA methylases in Escherichia coli K12 cells.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Binding Sites; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Escherichia coli; Genes, Viral; Methyltransferases; Phenotype; T-Phages; Transfection; Viral Proteins | 1985 |
Distribution patterns for 5-methylcytosine among apurinic DNAs from several sources.
Topics: 5-Methylcytosine; Animals; Apurinic Acid; Base Sequence; Cytosine; DNA; Escherichia coli; Guinea Pigs; Liver; Lymph Nodes; Mice; Organ Specificity; Polynucleotides; Rabbits; Rats; Species Specificity | 1985 |
Type III 5-methylcytosine modification of DNA in Neisseria gonorrhoeae.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; Neisseria gonorrhoeae; Plasmids; Substrate Specificity | 1985 |
An improved radioimmunoassay for the quantitation of DNA methylation.
Topics: 5-Methylcytosine; Animals; Antibody Specificity; Bromodeoxycytidine; Cattle; Chromatography, High Pressure Liquid; Cross Reactions; Cytosine; Deoxycytidine; DNA; Fishes; Methylation; Rabbits; Radioimmunoassay | 1986 |
Genomic 5-methylcytosine determination by 32P-postlabeling analysis.
Topics: 5-Methylcytosine; Animals; Autoradiography; Bronchi; Cell Line; Chromatography, Thin Layer; Cytosine; DNA; Genes; Humans; Lung; Macaca mulatta; Methylation; Phosphorus Radioisotopes | 1986 |
DNA methylation in thermophilic bacteria: N4-methylcytosine, 5-methylcytosine, and N6-methyladenine.
Topics: 5-Methylcytosine; Adenine; Bacteria; Cytosine; DNA, Bacterial; Methylation; Nucleic Acid Denaturation | 1985 |
Fitting methylation into development.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Nucleosomes | 1985 |
Hypomethylation of repair patches in HeLa cells.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Repair; HeLa Cells; Humans; Methylation; Ultraviolet Rays | 1985 |
Methylation patterns in the gene for the alpha subunit of chorionic gonadotropin are inherited with variable fidelity in clonal lineages of human fibroblasts.
Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cells, Cultured; Chorionic Gonadotropin; Cytosine; DNA Replication; Gene Expression Regulation; Genes; Humans; Methylation | 1985 |
SCE and DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytosine; Deer; DNA; DNA Replication; Female; Fibroblasts; Male; Methylation; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange | 1984 |
Chemical carcinogen-mediated decreases in DNA 5-methylcytosine content of BALB/3T3 cells.
Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Fibroblasts; In Vitro Techniques; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenanthrenes | 1984 |
Differentiation of two mouse cell lines is associated with hypomethylation of their genomes.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Differentiation; Cell Line; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; Genes; Kinetics; Leukemia, Experimental; Methylation; Mice; Teratoma | 1984 |
Growth conditions of F9 embryonal carcinoma cells affect the degree of DNA methylation.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; Embryonal Carcinoma Stem Cells; Gene Expression Regulation; H-2 Antigens; Male; Methylation; Mice; Neoplastic Stem Cells; Stem Cells; Teratoma | 1984 |
Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; Electrophoresis, Agar Gel; Gene Amplification; Gene Expression Regulation; Genes; Liver Neoplasms, Experimental; Nucleic Acid Hybridization; Rats; Repetitive Sequences, Nucleic Acid; RNA, Neoplasm; RNA, Ribosomal; Silver Nitrate; Staining and Labeling; Transcription, Genetic | 1981 |
Inverse relationship between transcriptional activity and 5-methylcytosine content of DNA in polytene chromosomes of sciara coprophila.
Topics: 5-Methylcytosine; Animals; Chromosome Banding; Chromosomes; Cytosine; Diptera; DNA; Larva; RNA; Transcription, Genetic | 1981 |
Specifically unmethylated cytidylic-guanylate sites in Herpesvirus saimiri DNA in tumor cells.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; Cytosine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; DNA, Viral; Herpesvirus 2, Saimiriine; Leukemia, Experimental; Methylation; Tumor Virus Infections | 1982 |
Analogues of 5-methyl cytosine and early embryonic development.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytosine; DNA; Embryo, Nonmammalian; Gene Expression Regulation; Methylation; Sea Urchins | 1982 |
DNA methylation affecting the expression of murine leukemia proviruses.
Topics: 5-Methylcytosine; AKR murine leukemia virus; Animals; Azacitidine; Cell Line; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Leukemia Virus, Murine; Methylation; Mice; Moloney murine leukemia virus; Rats; Recombination, Genetic; Transfection | 1982 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin | 1983 |
Specific effects of 5-fluoropyrimidines and 5-azapyrimidines on modification of the 5 position of pyrimidines, in particular the synthesis of 5-methyluracil and 5-methylcytosine in nucleic acids.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytidine; Cytosine; DNA; Liver; Methylation; Mice; Pyrimidines; RNA, Transfer; Thymine | 1983 |
Exclusion of exogenous 5-methyl-2'-deoxycytidine from DNA in human leukemic cells. A study with [2(-14)C]- and [methyl-14C]5-methyl-2'-deoxycytidine.
Topics: 5-Methylcytosine; Cell Line; Cytosine; Deoxycytidine; DNA; Humans; Leucine; Leukemia, Lymphoid; RNA; Thymidine; Uridine | 1983 |
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action.
Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice | 1983 |
DNA hypomethylation in Morris hepatomas.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Liver Neoplasms, Experimental; Methylation; Neoplasm Transplantation; Rats; Rats, Inbred ACI | 1983 |
Restriction sites containing CpG show a higher frequency of polymorphism in human DNA.
Topics: 5-Methylcytosine; Alleles; Base Sequence; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Genes; Genotype; Humans; Methylation; Pedigree; Polymorphism, Genetic | 1984 |
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype | 1984 |
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic | 1984 |
Methylation of either cytosine in the recognition sequence CGCG inhibits ThaI cleavage of DNA.
Topics: 5-Methylcytosine; Adenoma; Animals; Azacitidine; Base Sequence; Cell Line; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Pituitary Neoplasms; Rats; Substrate Specificity | 1984 |
5'-Methyl-cytosine in the macronuclear DNA of Blepharisma japonicum.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chromatography, High Pressure Liquid; Ciliophora; Cytosine; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Electrophoresis, Agar Gel; Hydrolysis | 1984 |
[Distribution of 5-methylcytosine in phage lambda genome methylated by DNA methylase Eco RII].
Topics: 5-Methylcytosine; Bacteriophage lambda; Cytosine; DNA-Cytosine Methylases; DNA, Viral; Genes, Viral; Methylation; Methyltransferases | 1982 |
Estimation of the amount of 5-methylcytosine in Drosophila melanogaster DNA by amplified ELISA and photoacoustic spectroscopy.
Topics: 5-Methylcytosine; Acoustics; Animals; Bacteriophage phi X 174; Cell Line; Cytosine; DNA; DNA, Viral; Drosophila melanogaster; Enzyme-Linked Immunosorbent Assay; Female; Fetus; Fibroblasts; Humans; Insecta; Spectrophotometry | 1984 |
Methylation of milk-borne and genetically transmitted mouse mammary tumor virus proviral DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Restriction Enzymes; DNA, Viral; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred Strains; Milk; Recombination, Genetic | 1980 |
Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells.
Topics: 5-Methylcytosine; Alpharetrovirus; Animals; Base Sequence; Cell Line; Cell Transformation, Viral; Chick Embryo; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Recombination, Genetic | 1980 |
Enzymatic analysis of 5-methylcytosine content in eukaryotic DNA. Study of intracellular Simian Virus 40 DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease I; Deoxyribonucleases; DNA, Viral; Electrophoresis, Paper; Endonucleases; Haplorhini; Methods; Simian virus 40 | 1980 |
Bacteriophage XP-12-induced exonuclease which preferentially hydrolyzes nicked DNA.
Topics: 5-Methylcytosine; Bacteriophages; Chromatography, DEAE-Cellulose; Cytosine; DNA, Bacterial; DNA, Viral; Exonucleases; Substrate Specificity; Xanthomonas | 1980 |
Identification of 5-methylcytosine in DNA fragments immobilized on nitrocellulose paper.
Topics: 5-Methylcytosine; Animals; Autoradiography; Bacteriophage phi X 174; Base Composition; Cattle; Chlamydomonas; Chloroplasts; Collodion; Cricetinae; Cricetulus; Cytosine; Diazonium Compounds; DNA; DNA Restriction Enzymes; DNA, Satellite; DNA, Viral; Escherichia coli; Immunosorbent Techniques; Paper; Rabbits; Thymus Gland | 1980 |
DNA methylation and the frequency of CpG in animal DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Mutation; Thymine | 1980 |
The 5'-cytosine in CCGG1 is methylated in two eukaryotic DNAs and Msp I is sensitive to methylation at this site.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cytosine; Deoxyribonucleases; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Liver; Liver Neoplasms, Experimental; Oligodeoxyribonucleotides; Oligonucleotides; Rats | 1980 |
Frog virus 3 DNA is heavily methylated at CpG sequences.
Topics: 5-Methylcytosine; Adenine; Animals; Base Sequence; Cells, Cultured; Chromatography, Thin Layer; Cytosine; DNA; DNA Restriction Enzymes; DNA, Viral; Fishes; Iridoviridae | 1980 |
Sequence specificity of methylation in higher plant DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Mice; Plants | 1981 |
Isolation by restriction endonuclease digestion and base-specific affinity chromatography of rat-embryo DNA sequences disproportionately enriched in virogenic bromodeoxyuridine.
Topics: 5-Methylcytosine; Animals; Base Sequence; Bromodeoxyuridine; Cells, Cultured; Chromatography, Affinity; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Rats; Virus Activation | 1981 |
Distribution of 5-methylcytosine in the DNA of somatic and germline cells from bovine tissues.
Topics: 5-Methylcytosine; Animals; Cattle; Cytosine; DNA; DNA Restriction Enzymes; Genes; Male; Organ Specificity; Spermatozoa; Thymus Gland | 1981 |
DNA methylation in normal and SV40-transformed human fibroblasts.
Topics: 5-Methylcytosine; Cell Line; Cell Transformation, Viral; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Fibroblasts; Humans; Male; Methylation; Methyltransferases; Simian virus 40 | 1981 |
The distribution of 5-methylcytosine in guinea pig satellite DNA's as probed by the restriction enzymes Msp I and Hpa II.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cricetinae; Cytosine; DNA Restriction Enzymes; DNA, Satellite | 1980 |
DNA methylation levels in normal and chemically-transformed mouse 3T3 cells.
Topics: 5-Methylcytosine; Animals; Base Composition; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Cytosine; DNA; Methylation; Methylcholanthrene; Mice | 1982 |
Relative levels of methylation in human growth hormone and chorionic somatomammotropin genes in expressing and non-expressing tissues.
Topics: 5-Methylcytosine; Cell Nucleus; Cloning, Molecular; Cytosine; DNA; DNA Restriction Enzymes; Female; Genes; Growth Hormone; Humans; Hydatidiform Mole; Methylation; Nucleic Acid Hybridization; Pituitary Gland, Anterior; Placenta; Placental Lactogen; Pregnancy; Uterine Neoplasms | 1982 |
Cytosine methylation of the sequence GATC in a mycoplasma.
Topics: 5-Methylcytosine; Acholeplasma laidlawii; Base Composition; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; Methylation | 1982 |
Novel mutations of Escherichia coli that produce recombinogenic lesions in DNA. V. Recombinogenic plasmids from arl mutants of Escherichia coli are unusually sensitive to nuclease S1 and partially deficient in cytosine methylation at C-C-(A/T)-G-G sequenc
Topics: 5-Methylcytosine; Base Sequence; Chromatography, High Pressure Liquid; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; DNA, Recombinant; Electrophoresis, Agar Gel; Endonucleases; Escherichia coli; Mutation; Plasmids; Recombination, Genetic; Single-Strand Specific DNA and RNA Endonucleases | 1982 |
Hypomethylation of HeLa cell DNA and the absence of 5-methylcytosine in SV40 and adenovirus (type 2) DNA: analysis by HPLC.
Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Cell Line; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Cytosine; DNA, Neoplasm; DNA, Viral; HeLa Cells; Humans; Kidney; Methylation; Simian virus 40 | 1982 |
[5-Methylcytosine content in erythroleukemic cells of rats after induction with dimethylsulfoxide].
Topics: 5-Methylcytosine; Animals; Cytosine; Dimethyl Sulfoxide; DNA Restriction Enzymes; DNA, Neoplasm; Leukemia, Experimental; Rats | 1982 |
Hypomethylation of Epstein-Barr virus DNA in the nonproducer B-cell line EBR.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Base Sequence; Callitrichinae; Cell Line; Cell Transformation, Viral; Cytosine; DNA Restriction Enzymes; DNA, Viral; Herpesvirus 4, Human; Humans | 1982 |
Mouse mammary tumor virus proviral sequences congenital to C3H/Sm mice are differentially hypomethylated in chemically induced, virus-induced, and spontaneous mammary tumors.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; DNA, Viral; Female; Gene Amplification; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H | 1982 |
Epstein-Barr HR-1 virion DNA is very highly methylated.
Topics: 5-Methylcytosine; Cytosine; DNA, Viral; Herpesvirus 4, Human; Methylation; Virion | 1983 |
Characterization of DNA methylation in the rat.
Topics: 5-Methylcytosine; Aging; Animals; Base Composition; Base Sequence; Cell Differentiation; Cell Line; Cytosine; DNA; DNA Restriction Enzymes; Embryo, Mammalian; Kidney; Liver; Methylation; Organ Specificity; Rats; Rats, Inbred Strains | 1982 |
DNA methylation patterns in the 5S DNAs of Xenopus laevis.
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Erythrocytes; Liver; Methylation; Xenopus | 1983 |
Can DNA methylation regulate gene expression?
Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA; DNA Restriction Enzymes; DNA, Viral; Female; Genes; Humans; Methylation; Oocytes; Operon; Transcription, Genetic; Xenopus | 1983 |
Variation in the DNA methylation pattern of expressed and nonexpressed genes in chicken.
Topics: 5-Methylcytosine; Actins; Animals; Chickens; Cloning, Molecular; Crystallins; Cytosine; DNA; DNA Restriction Enzymes; Genes; Glyceraldehyde-3-Phosphate Dehydrogenases; Methylation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; RNA, Ribosomal; Tissue Distribution; Tubulin; Xenopus | 1983 |
The 5-methylcytosine content of DNA from human tumors.
Topics: 5-Methylcytosine; Brain Chemistry; Cytosine; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Female; Humans; Methylation; Neoplasms; Placenta; Pregnancy; Structure-Activity Relationship | 1983 |
Primary structure of the human proenkephalin gene.
Topics: 5-Methylcytosine; Base Sequence; Biological Evolution; Cytosine; DNA Restriction Enzymes; Enkephalins; Humans; Nucleic Acid Hybridization; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Repetitive Sequences, Nucleic Acid | 1983 |
Cloning and physical mapping of an early region of the bacteriophage T4 genome.
Topics: 5-Methylcytosine; Chromosome Deletion; Chromosome Mapping; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; Genes, Viral; T-Phages | 1984 |
DNA methylation inhibits the transfecting activity of replicative- form phi X174 DNA.
Topics: 5-Methylcytosine; Bacteriophage phi X 174; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; DNA Restriction Enzymes; DNA, Viral; Escherichia coli; Methyltransferases | 1984 |
DNA methylation in the fungi.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Fungal; Fungi; Methylation; Species Specificity | 1984 |
Methylation pattern of mouse mitochondrial DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Mitochondrial; L Cells; Methylation; Mice; Mitochondria; Mitochondria, Liver; Nucleic Acid Hybridization; Plasmids | 1984 |
Mouse mammary tumor virus DNA methylation: tissue-specific variation.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Lactation; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Pregnancy; Repetitive Sequences, Nucleic Acid; RNA, Viral; Spleen; Transcription, Genetic | 1984 |
The B----Z transition in two synthetic oligonucleotides: d(C-2-amino-ACGTG) and d(m5CGCAm5CGTGCG) studied by IR, NMR and CD spectroscopies.
Topics: 5-Methylcytosine; Base Sequence; Circular Dichroism; Cytosine; Deoxyadenosines; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Spectrophotometry, Infrared; Structure-Activity Relationship | 1984 |
Formation of 5-hydroxymethylcytosine-containing pyrimidine dimers in UV-irradiated bacteriophage T4 DNA.
Topics: 5-Methylcytosine; Cytosine; DNA, Viral; Escherichia coli; Pyrimidine Dimers; T-Phages; Ultraviolet Rays | 1983 |
Immunological visualization of 5-methylcytosine-rich regions in Indian Muntjac metaphase chromosomes.
Topics: 5-Methylcytosine; Animals; Chromosomes; Cytosine; Deer; DNA, Single-Stranded; Fluorescent Antibody Technique; Male; Metaphase | 1983 |
5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA, Fungal; Saccharomyces cerevisiae | 1984 |
The biological significance of meiosis.
Topics: 5-Methylcytosine; Aging; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; Gene Conversion; Meiosis; Mutation; Plants; Recombination, Genetic; Reproduction; Saccharomyces cerevisiae; Selection, Genetic | 1984 |
Immunochemical evidence for the presence of 5mC, 6mA and 7mG in human, Drosophila and mealybug DNA.
Topics: 5-Methylcytosine; Adenine; Animals; Antibodies; Chemical Phenomena; Chemistry; Cytosine; DNA; Drosophila melanogaster; Female; Guanine; Humans; Immunochemistry; Insecta; Male; Placenta; Rats; Species Specificity; Spermatozoa | 1983 |
Quantitative determination of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cricetinae; Cytosine; DNA; DNA, Viral; Drosophila melanogaster; Hydrolysis; Mice | 1983 |
[5-methylcytosine is lacking in the DNA of Drosophila melanogaster and Drosophila virilis].
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; DNA; Drosophila; Drosophila melanogaster; Methylation; Species Specificity | 1984 |
Region-specific recombination in phage T4. I. A special glucosyl-dependent recombination system.
Topics: 5-Methylcytosine; Capsid; Cytosine; DNA, Viral; Escherichia coli; Genes, Viral; Glucosyltransferases; Hot Temperature; Mutation; Recombination, Genetic; T-Phages | 1980 |
Shutoff of lambda gene expression by bacteriophage T4: role of the T4 alc gene.
Topics: 5-Methylcytosine; Bacteriophage lambda; Cytosine; DNA, Circular; Escherichia coli; Genes, Viral; Mutation; Nucleic Acid Conformation; Nucleic Acid Hybridization; Protein Biosynthesis; RNA, Viral; T-Phages; Time Factors; Transcription, Genetic; Viral Interference | 1980 |
Clonal inheritance of the pattern of DNA methylation in mouse cells.
Topics: 5-Methylcytosine; Animals; Bacteriophage phi X 174; Cloning, Molecular; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Haemophilus influenzae; L Cells; Methylation; Methyltransferases; Mice | 1982 |
1H-NMR study of the interaction of daunomycin with B-DNA helices of methylated oligodeoxynucleotides.
Topics: 5-Methylcytosine; Cytosine; Daunorubicin; DNA; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1984 |
Poly(pyrimidine) . poly(purine) synthetic DNAs containing 5-methylcytosine form stable triplexes at neutral pH.
Topics: 5-Methylcytosine; Cytosine; DNA; Drug Stability; Hydrogen-Ion Concentration; Indicators and Reagents; Nucleic Acid Denaturation; Polydeoxyribonucleotides; Repetitive Sequences, Nucleic Acid; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics | 1984 |
The senescence of postmitotic mammalian cells: a cell-clock hypothesis.
Topics: 5-Methylcytosine; Animals; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytosine; DNA; Lung; Mitosis; Models, Biological; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic | 1984 |
Hypomethylation of DNA in meiotic and postmeiotic rooster testis cells.
Topics: 5-Methylcytosine; Animals; Chickens; Chromatography, High Pressure Liquid; Cytosine; DNA; Liver; Male; Meiosis; Methylation; Spermatogenesis; Spermatozoa; Testis | 1984 |
[Effect of adrenaline on nucleotide composition and the degree of DNA methylation in the canine myocardium].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Dogs; Epinephrine; Heart; Male; Methylation; Myocardium; Nucleotides | 1984 |
Bilirubin incorporation into spiroplasma membranes and methylation of spiroplasmal DNA.
Topics: 5-Methylcytosine; Adenine; Base Composition; Bilirubin; Cell Membrane; Cytosine; DNA, Bacterial; Guanine; Methylation; Spiroplasma | 1984 |
Gas chromatography-mass spectrometry characteristics of methylated perfluoroacyl derivatives of cytosine and 5-methylcytosine.
Topics: 5-Methylcytosine; Cytosine; Fluorobenzenes; Gas Chromatography-Mass Spectrometry | 1984 |
Evidence for surface effects in an electron-capture detector.
Topics: 5-Methylcytosine; Chemical Phenomena; Chemistry, Physical; Chromatography, Gas; Cytosine; DDT; Flucytosine; Methoxychlor; Pesticides; Surface Properties; Temperature | 1984 |
Direct determination of uracil in [32P,uracil-3H]poly(dA.dT) and bisulfite-treated phage PM2 DNA.
Topics: 5-Methylcytosine; Bacteriophages; Chromatography, Thin Layer; Cytosine; Deoxyuracil Nucleotides; DNA; DNA Glycosylases; DNA, Viral; Humans; N-Glycosyl Hydrolases; Placenta; Poly dA-dT; Polydeoxyribonucleotides; Polyethyleneimine; Sulfites; Uracil; Uracil-DNA Glycosidase | 1984 |
Maintenance of DNA integrity during murine erythroleukemia cell differentiation induced by ethionine and other hypomethylation agents.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Chromatography, High Pressure Liquid; Cytosine; DNA; Ethionine; Leukemia, Erythroblastic, Acute; Methylation; Mice; Nucleic Acid Conformation | 1983 |
5-methylcytosine is localized in nucleosomes that contain histone H1.
Topics: 5-Methylcytosine; Animals; Antibody Specificity; Cytosine; DNA; Histones; Methylation; Mice; Nucleosomes | 1983 |
Extent of DNA methylation in human tumor cells.
Topics: 5-Methylcytosine; Base Composition; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms | 1983 |
DNA methylation in differentiating mouse teratocarcinoma and erythroleukemia cells.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease I; DNA; Gene Expression Regulation; Globins; Hybrid Cells; Leukemia, Erythroblastic, Acute; Methylation; Mice; Teratoma; Transcriptional Activation | 1984 |
DNA methylation versus gene expression.
Topics: 5-Methylcytosine; Animals; Cytosine; Dinucleoside Phosphates; DNA; DNA Replication; DNA, Ribosomal; Gene Expression Regulation; Genes; Methylation; Oligonucleotides; Transcription, Genetic; Xenopus laevis | 1984 |
Analysis of modified bases in DNA by stable isotope dilution gas chromatography-mass spectrometry: 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Reference Standards; Thymus Gland | 1983 |
[Effect of vitamin B12 on liver and kidney DNA methylation in guinea pigs in the presence of methionine and ATP].
Topics: 5-Methylcytosine; Adenosine Triphosphate; Animals; Cytosine; DNA; Drug Interactions; Guinea Pigs; Kidney; Liver; Male; Methionine; Methylation; Vitamin B 12 | 1983 |
Exposure of JB-6 mouse epidermal cells to 12-O-tetradecanoyl-phorbol-13-acetate is not accompanied by a significant change in total DNA-cytosine methylation.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; DNA; Mice; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1983 |
DNA-methylating activity of mycobacteria.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Bacterial; DNA, Viral; Kinetics; Methylation; Methyltransferases; Mycobacterium; S-Adenosylmethionine; Thymus Gland | 1983 |
Absence of detectable 5-methylcytosine in DNA of embryos of the brine shrimp, Artemia.
Topics: 5-Methylcytosine; Animals; Artemia; Cattle; Chromatography, High Pressure Liquid; Cytosine; DNA; Embryo, Nonmammalian; Male; Purines; Pyrimidines; Salmon; Spermatozoa | 1984 |
Relationship of DNA methylation level to the presence of heterochromatin in mealybugs.
Topics: 5-Methylcytosine; Cytosine; Dosage Compensation, Genetic; Gene Expression Regulation; Heterochromatin; Insecta; Methylation; Sex Differentiation; Species Specificity | 1984 |
[A simple selective method for determination of DNA-cytosine-methylase in cell homogenates].
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Escherichia coli; Kinetics; Methyltransferases; Radioisotope Dilution Technique; Tritium | 1982 |
DNA methylation patterns of human pachytene spermatocytes.
Topics: 5-Methylcytosine; Adult; Aged; Centromere; Chromosomes; Cytosine; DNA; Humans; Immunoenzyme Techniques; Male; Meiosis; Methylation; Middle Aged; Spermatocytes; Spermatogenesis; Spermatozoa | 1982 |
Is DNA methylation responsible for mammalian X chromosome inactivation?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Female; Gene Expression Regulation; Humans; Immunologic Techniques; Methylation; Sex Chromosomes; X Chromosome | 1982 |
[Methylated nitrogen bases of DNA of the yeast Saccharomyces cerevisiae].
Topics: 5-Methylcytosine; Adenine; Cell Nucleus; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Fungal; Methylation; Saccharomyces cerevisiae; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1982 |
5-Methylcytosine formation in wheat embryo DNA.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Kinetics; Methionine; Methyltransferases; Plants; S-Adenosylmethionine; Serine; Triticum | 1980 |
5-methylcytosine in the DNA of the polytene chromosomes of the diptera Sciara coprophila, Drosophila melanogaster and D. persimilis.
Topics: 5-Methylcytosine; Animals; Cytosine; Diptera; DNA; Drosophila; Drosophila melanogaster; Methylation; Species Specificity | 1980 |
Methylated bases in the DNA of the ciliate Stylonychia mytilus.
Topics: 5-Methylcytosine; Adenine; Animals; Cell Nucleus; Ciliophora; Cytosine; DNA | 1981 |
Deoxyribonucleic acid methylation in mycobacteria.
Topics: 5-Methylcytosine; Adenine; Base Composition; Cytosine; DNA, Bacterial; Methylation; Mycobacterium; Mycobacterium phlei; Mycobacterium tuberculosis | 1981 |
Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Cell Differentiation; Cytosine; Gene Expression Regulation; Genes; Immunoglobulin gamma-Chains; Immunoglobulin J-Chains; Immunoglobulin mu-Chains; Methylation; Mice; Recombination, Genetic; Transcription, Genetic | 1981 |
Immunoglobulin heavy chain genes: demethylation accompanies class switching.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; Gene Expression Regulation; Genes; Immunoglobulin Constant Regions; Immunoglobulin delta-Chains; Immunoglobulin gamma-Chains; Immunoglobulin Heavy Chains; Immunoglobulin mu-Chains; Liver; Mice; Transcription, Genetic | 1981 |
[Increase in the degree of the methylation of the palindromic sequences in the DNA of cows with chronic lympholeukemia].
Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cattle Diseases; Cytosine; DNA; DNA, Neoplasm; Female; Leukemia, Lymphoid; Lymphocytes; Methylation; Repetitive Sequences, Nucleic Acid | 1983 |
Formation and removal of methylated nucleosides in nucleic acids of mammalian cells.
Topics: 5-Methylcytosine; Alkylating Agents; Alkylation; Animals; Carcinogens; Cytosine; Deoxyribonucleosides; DNA; Ethionine; Methylation; Nitrosamines; Species Specificity | 1983 |
DNA methylation decreases in aging but not in immortal cells.
Topics: 5-Methylcytosine; Aging; Animals; Cell Division; Cell Line; Cricetinae; Cytosine; DNA; Fibroblasts; Humans; Mesocricetus; Methylation; Mice; Time Factors | 1983 |
The 5-methylcytosine content of highly repeated sequences in human DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; Female; Genes; Humans; Kinetics; Male; Methylation; Nucleic Acid Hybridization; Placenta; Pregnancy; Repetitive Sequences, Nucleic Acid; Spermatozoa | 1983 |
Tissue-specific differences in DNA methylation in various mammals.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; Mammals; Methylation; Species Specificity; Tissue Distribution | 1983 |
5-methylcytosine content in different organs of the mouse and rat, several tumors and in mice embryos.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA, Neoplasm; Embryo, Mammalian; Female; Kidney; Liver; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Pregnancy; Rats | 1983 |
Improved method for determination of 5-methylcytosine by ion-pair reversed-phase high-performance liquid chromatography.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cytosine; DNA; Nicotiana; Plants, Toxic | 1983 |
Variable 5-methylcytosine levels in human tumor cell lines and fresh pediatric tumor explants.
Topics: 5-Methylcytosine; Autoradiography; Cell Line; Cerebellar Neoplasms; Cytosine; DNA; Fibroblasts; Humans; Medulloblastoma; Neoplasms; Neuroblastoma; Retinoblastoma | 1983 |
DNA methylation and the regulation of globin gene expression.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Gene Expression Regulation; Genes; Globins; Humans; Methylation; Transcription, Genetic | 1983 |
Methylation of adenovirus genes in transformed cells and in vitro: influence on the regulation of gene expression?
Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Base Sequence; Carrier Proteins; Cell Transformation, Viral; Cytosine; DNA; DNA-Binding Proteins; Female; Gene Expression Regulation; Genes, Viral; Oocytes; Viral Proteins; Xenopus laevis | 1981 |
Control of hemoglobin expression in chick embryonic development.
Topics: 5-Methylcytosine; Animals; Brain; Chick Embryo; Chickens; Cloning, Molecular; Cytosine; DNA; Genes; Globins; Hematopoietic Stem Cells; Hemoglobins; Macromolecular Substances; Male; Methylation; Spermatozoa | 1982 |
Topographical distribution of 5-methylcytosine in animal and plant DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Gene Expression Regulation; Methylation; Mice; Triticum | 1982 |
[Modification of DNA-specific methylation in tissues of healthy and tumor bearing (sarcoma 45) rats under the effect of an active alkylating cancerolytic agent].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA, Neoplasm; Kinetics; Liver; Male; Methylation; Osteosarcoma; Rats; Spleen; Testis | 1980 |
DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cloning, Molecular; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Gene Expression Regulation; Mice; Moloney murine leukemia virus; Transfection; Virus Replication | 1981 |
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.
Topics: 5-Methylcytosine; Adenine Phosphoribosyltransferase; Animals; Base Sequence; Cricetinae; Cytosine; Gene Expression Regulation; L Cells; Methylation; Mice; Pentosyltransferases | 1982 |
Tissue specificity and clustering of methylated cystosines in bovine satellite I DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Cytosine; DNA, Satellite; Methylation; Tissue Distribution | 1982 |
Hybridization analysis of the methylated bases of Escherichia coli DNA.
Topics: 5-Methylcytosine; Cytosine; DNA, Bacterial; Escherichia coli; Methylation; Nucleic Acid Hybridization | 1980 |
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells.
Topics: 5-Methylcytosine; Cell Line; Cells, Cultured; Cytosine; DNA; DNA, Neoplasm; Female; Fibroblasts; Humans; Kinetics; Lymphocytes; Nucleic Acid Renaturation; Organ Specificity; Pregnancy; Skin | 1982 |
A new thymidylate biosynthesis in Xanthomonas oryzae infected by phage Xp 12.
Topics: 5-Methylcytosine; Aminohydrolases; Bacteriophages; Cytosine; Deamination; DNA, Viral; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Xanthomonas | 1982 |
Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA.
Topics: 5-Methylcytosine; Cytosine; Deamination; Hot Temperature; Hydrogen-Ion Concentration; Mutation | 1982 |
Nuclease-sensitivity of methylated DNA as a probe for chromatin reconstitution by genotoxicants.
Topics: 5-Methylcytosine; Animals; Chromatin; Cricetinae; Cytosine; Dichlorvos; DNA; Doxorubicin; Ethyl Methanesulfonate; Female; Kinetics; Micrococcal Nuclease; Time Factors; Ultraviolet Rays | 1982 |
[DNA metabolic characteristics of the rat brain in the process of developing a conditioned reflex].
Topics: 5-Methylcytosine; Animals; Brain; Conditioning, Classical; Cytosine; DNA; DNA Replication; Escape Reaction; Hydroxyurea; Male; Rats | 1982 |
Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; X-Ray Diffraction | 1982 |
Methylated nucleic acid bases in Mycobacterium and mycobacteriophage DNA.
Topics: 5-Methylcytosine; Adenine; Cytosine; DNA, Bacterial; DNA, Viral; Methylation; Mycobacteriophages; Mycobacterium | 1982 |
The inheritance of methylation patterns in vertebrates.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation; Humans; Methyltransferases; X Chromosome | 1981 |
Characteristics of enzymatic DNA methylation in cultured cells of human and hamster origin, and the effect of DNA replication inhibition.
Topics: 5-Methylcytosine; Animals; Arabinonucleotides; Cells, Cultured; Cricetinae; Cricetulus; Culture Media; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Female; Humans; Methyltransferases; Ovary | 1982 |
Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction.
Topics: 5-Methylcytosine; Animals; Carcinoma, Ehrlich Tumor; Cattle; Cattle Diseases; Cytosine; DNA; DNA, Neoplasm; Embryo, Mammalian; Female; Hydrocortisone; Liver; Lymphoma; Male; Methylation; Mice; Myocardium; Pregnancy; Rats; Repetitive Sequences, Nucleic Acid; Thymus Gland | 1981 |
Determination of 5-methylcytosine from plant DNA by high-performance liquid chromatography.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA; Hydrolysis; Plants; Species Specificity | 1981 |
[5-Methylcytosine in pyrimidine sequences of plant and animal DNA: specificity of methylation].
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Genes, Regulator; Methyltransferases; Plants; Pyrimidines; Species Specificity | 1981 |
[Cortisol-induced changes in methylation of repeating sequences of transcriptionally active DNA from rat liver].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Replication; Hydrocortisone; Kinetics; Liver; Male; Methylation; Nucleic Acid Hybridization; Rats; Transcription, Genetic | 1981 |
[Changes in DNA methylation in guinea pig liver and kidney during vitamin B12 administration].
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Guinea Pigs; Kidney; Liver; Male; Methylation; Vitamin B 12 | 1981 |
Clusters of repeated sequences of chicken DNA are extensively methylated but contain specific undermethylated regions.
Topics: 5-Methylcytosine; Animals; Chickens; Cytosine; DNA; Electrophoresis, Agar Gel; Genes; Methylation; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid | 1981 |
Synthesis of 4-triazolopyrimidinone nucleotide and its application in synthesis of 5-methylcytosine-containing oligodeoxyribonucleotides.
Topics: 5-Methylcytosine; Cytosine; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Phosphorylation; Pyrimidinones; Triazoles | 1981 |
Polymorphism of 5-methylcytosine-rich DNA in human acrocentric chromosomes.
Topics: 5-Methylcytosine; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, 13-15; Chromosomes, Human, 21-22 and Y; Cytosine; DNA; Histocytochemistry; Humans; Polymorphism, Genetic | 1981 |
5-Methylcytosine in the highly repetitive DNA's of the guinea pig (Cavia porcellus).
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA, Satellite; Guinea Pigs; Oligonucleotides; Pyrimidine Nucleotides | 1980 |
Methylation of DNA in L cells on replication.
Topics: 5-Methylcytosine; Animals; Cell Division; Cytosine; DNA; DNA Replication; L Cells; Methionine; Methylation; Mice; Oligodeoxyribonucleotides | 1980 |
Intragenomic distribution of 5-methylcytosine in various forms of human and murine leukemic cells.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Deoxyribonucleases; DNA, Neoplasm; Humans; Leukemia; Leukemia L5178; Leukocytes; Lymphocytes; Magnesium; Methylation; Mice; Phytohemagglutinins; Transcription, Genetic | 1980 |
[Nucleotide composition and the methylated cytosine level in the DNA from a cancerous stomach tumor].
Topics: 5-Methylcytosine; Adenocarcinoma; Base Composition; Cytosine; DNA, Neoplasm; Duodenal Ulcer; Gastric Mucosa; Humans; Male; Methylation; Middle Aged; Nucleotides; Stomach Neoplasms | 1980 |
Methylated bases in mycoplasmal DNA.
Topics: 5-Methylcytosine; Acholeplasma laidlawii; Adenine; Base Composition; Cytosine; DNA, Bacterial; Methylation; Mycoplasma | 1980 |
Mechanism of hydroxylamine mutagenesis: an infrared study of the association in non-polar solutions of 5-methyl-N4-hydroxycytosines.
Topics: 5-Methylcytosine; Chemical Phenomena; Chemistry; Cytosine; Hydrogen Bonding; Molecular Conformation; Solutions; Spectrophotometry, Infrared; Temperature | 1980 |
Organization, replication and modification of the human genome: synthesis and methylation of palindromic, repeated and unique HeLa nDNA sequences during the S-phase.
Topics: 5-Methylcytosine; Cytosine; DNA Replication; HeLa Cells; Humans; Interphase; Methylation; Repetitive Sequences, Nucleic Acid; Transcription, Genetic | 1980 |
Patterns of DNA methylation of the parathyroid hormone-related protein gene in human lung carcinoma.
Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Lung; Lung Neoplasms; Male; Methylation; Neoplasm Proteins; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Restriction Mapping; Spermatozoa | 1995 |
Strand bias in mutation involving 5-methylcytosine deamination in the human hprt gene.
Topics: 5-Methylcytosine; Chi-Square Distribution; Codon; Cytosine; Databases, Factual; Deamination; Dinucleoside Phosphates; DNA Repair; DNA, Complementary; Humans; Hypoxanthine Phosphoribosyltransferase; Methylation; Models, Genetic; Mutagenesis, Site-Directed; Nucleic Acid Heteroduplexes; Point Mutation; Transcription, Genetic | 1994 |
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine | 1993 |
A simple assay for monitoring the mutagenic effects of 5-methylcytosine deamination in Escherichia coli.
Topics: 5-Methylcytosine; Amino Acid Sequence; Base Sequence; Cytosine; Deamination; DNA Mutational Analysis; DNA Repair; DNA-Cytosine Methylases; Endodeoxyribonucleases; Escherichia coli; Lac Operon; Methylation; Molecular Sequence Data; Point Mutation; Suppression, Genetic | 1994 |
Methylation of single sites within the herpes simplex virus tk coding region and the simian virus 40 T-antigen intron causes gene inactivation.
Topics: 5-Methylcytosine; Animals; Antigens, Polyomavirus Transforming; Base Sequence; Cell Line; Cell Transformation, Viral; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; Gene Expression Regulation, Viral; In Vitro Techniques; Methylation; Molecular Sequence Data; Rats; RNA, Messenger; Simian virus 40; Simplexvirus; Thymidine Kinase | 1994 |
Methylation analysis by genomic sequencing of 5' region of mouse Pgk-1 gene and a cautionary note concerning the method.
Topics: 5-Methylcytosine; Animals; Artifacts; Base Sequence; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Dinucleoside Phosphates; Dosage Compensation, Genetic; Enhancer Elements, Genetic; Female; Male; Methylation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphoglycerate Kinase; Polymerase Chain Reaction; Promoter Regions, Genetic; Sequence Analysis, DNA; X Chromosome | 1993 |
Dependence of transcriptional repression on CpG methylation density.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Cell Nucleus; Cytosine; DNA-Cytosine Methylases; Gene Expression Regulation; Methylation; Transcription, Genetic; Transfection | 1994 |
Excision of ultraviolet-induced photoproducts of 5-methylcytosine from DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); Dinucleoside Phosphates; DNA; DNA Repair; Endodeoxyribonucleases; Humans; Methylation; Molecular Sequence Data; Polydeoxyribonucleotides; Thymine; Ultraviolet Rays | 1994 |
The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain.
Topics: 5-Methylcytosine; Amyloid beta-Protein Precursor; Animals; Brain Chemistry; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA-Binding Proteins; Gene Expression Regulation; Genes; Humans; Mammals; Methylation; Organ Specificity; Polymorphism, Restriction Fragment Length; Primates; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; Species Specificity | 1994 |
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
Topics: 5-Methylcytosine; Adult; Azacitidine; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, Pair 9; Cytosine; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Methylation; Microscopy, Electron | 1994 |
Methylation of cottontail rabbit papillomavirus DNA and tissue-specific expression in transgenic rabbits.
Topics: 5-Methylcytosine; Animals; Animals, Genetically Modified; Cottontail rabbit papillomavirus; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA (Cytosine-5-)-Methyltransferases; DNA, Recombinant; DNA, Viral; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Methylation; Microinjections; Organ Specificity; Papilloma; Papillomavirus Infections; Rabbits; Regulatory Sequences, Nucleic Acid; Skin; Skin Neoplasms; Tissue Distribution; Tumor Virus Infections | 1995 |
Promoter demethylation in MMTV/N-rasN transgenic mice required for transgene expression and tumorigenesis.
Topics: 5-Methylcytosine; Age Factors; Animals; Cytosine; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, ras; Lymphoma; Mammary Neoplasms, Experimental; Methylation; Mice; Mice, Transgenic; Promoter Regions, Genetic; Proto-Oncogene Mas; Repetitive Sequences, Nucleic Acid; Restriction Mapping; RNA, Messenger; RNA, Neoplasm; Transgenes | 1995 |
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Escherichia coli; Humans; Methylation; Molecular Structure; Mutagenesis; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymine | 1995 |
Methylation and p16: suppressing the suppressor.
Topics: 5-Methylcytosine; Carrier Proteins; Cell Transformation, Neoplastic; Cocarcinogenesis; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; DNA; Gene Expression Regulation; Genes, Tumor Suppressor; Genomic Imprinting; Humans; Methylation; Models, Genetic; Neoplasms | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
No effect of treatment with carcinogens on cytosine methylation of mitochondrial DNA isolated from rat organs by phenol-free alkaline extraction.
Topics: 5-Methylcytosine; Animals; Carcinogens; Cell Fractionation; Cytosine; DNA Damage; DNA, Mitochondrial; Hydrogen-Ion Concentration; Male; Methods; Methylation; Mitochondria; Rats; Rats, Sprague-Dawley; Restriction Mapping | 1995 |
DNA duplexes containing methylated bases or non-nucleotide inserts in the recognition site are cleaved by restriction endonuclease R.EcoRII in presence of canonical substrate.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; Substrate Specificity | 1995 |
Sse8387I, a useful eight base cutter for mammalian genome analysis (influence of methylation on the activity of Sse8387I).
Topics: 5-Methylcytosine; Adenine; Bacteriophage lambda; Base Sequence; Binding Sites; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA-Cytosine Methylases; DNA, Viral; Methylation; Molecular Sequence Data; Streptomyces; Substrate Specificity | 1995 |
CpNpG methylation in mammalian cells.
Topics: 3T3 Cells; 5-Methylcytosine; Animals; Base Sequence; Cell Line; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Methyltransferases; Mice; Molecular Sequence Data; Mutagens; Plasmids; Sequence Analysis; Sulfites; Transfection | 1995 |
Oxidative damage to 5-methylcytosine in DNA.
Topics: 5-Methylcytosine; Animals; Cattle; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; Endodeoxyribonucleases; Escherichia coli Proteins; Gamma Rays; Hydrolysis; In Vitro Techniques; Oxidation-Reduction; Polydeoxyribonucleotides; Tritium | 1995 |
Nucleoside monophosphate kinase may be the key enzyme preventing salvage of DNA 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Cattle; Cytosine; Deoxycytidine Monophosphate; DNA; Liver; Nucleoside-Phosphate Kinase; Phosphorylation; Rats; Substrate Specificity | 1993 |
A mechanism of inhibition of short-wavelength ultraviolet light-induced deamination of pyrimidine bases by ascorbic acid.
Topics: 5-Methylcytosine; Ascorbic Acid; Cytosine; Deamination; Gas Chromatography-Mass Spectrometry; Organosilicon Compounds; Radiation-Protective Agents; Silicon; Ultraviolet Rays | 1993 |
Isolation of Escherichia coli mutants lacking methylcytosine-dependent restriction systems for cloning extensively methylated frog virus 3 DNA.
Topics: 5-Methylcytosine; Ampicillin Resistance; Azacitidine; Base Sequence; Clone Cells; Cloning, Molecular; Cytosine; DNA Transposable Elements; DNA-Binding Proteins; DNA-Cytosine Methylases; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iridoviridae; Methylation; Molecular Sequence Data; Mutation; Plasmids; Substrate Specificity; Transformation, Genetic | 1993 |
Comparison of the effects of N6-methyldeoxyadenosine and N5-methyldeoxycytosine on transcription from nuclear gene promoters in barley.
Topics: 5-Methylcytosine; Base Sequence; Cell Nucleus; Cytosine; Deoxyadenosines; DNA, Plant; Gene Expression; Genes, Plant; Genes, Reporter; Hordeum; Methylation; Molecular Sequence Data; Mutagenesis, Insertional; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Transcription, Genetic | 1995 |
Sequence dependent effects of CpG cytosine methylation. A joint 1H-NMR and 31P-NMR study.
Topics: 5-Methylcytosine; Base Sequence; Computer Simulation; Cytosine; DNA; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Temperature; Thermodynamics | 1995 |
The gene and pseudogenes of rat S-adenosyl-L-homocysteine hydrolase.
Topics: 5-Methylcytosine; Adenosylhomocysteinase; Animals; Base Sequence; Cytosine; DNA Primers; Gene Expression; Genes; Humans; Hydrolases; Mice; Molecular Sequence Data; Pseudogenes; Rats; Regulatory Sequences, Nucleic Acid; Restriction Mapping; RNA, Messenger; Transcription, Genetic | 1995 |
Genotype-specific modifiers of transgene methylation and expression in the zebrafish, Danio rerio.
Topics: 5-Methylcytosine; Animals; Chloramphenicol O-Acetyltransferase; Cytosine; Female; Gene Expression Regulation; Genes, Reporter; Genes, Synthetic; Genotype; Male; Methylation; Mice; Mice, Transgenic; Temperature; Zebrafish | 1995 |
HpaII methyltransferase is mutagenic in Escherichia coli.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Repair; DNA-Cytosine Methylases; Escherichia coli; Haemophilus; Molecular Sequence Data; Mutagenesis; Thymine; Uracil | 1995 |
M.HhaI binds tightly to substrates containing mismatches at the target base.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Dinucleoside Phosphates; DNA; DNA-Cytosine Methylases; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Heteroduplexes; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Uracil | 1995 |
Enzymic removal of 5-methylcytosine from poly(dG-5-methyl-dC) by HeLa cell nuclear extracts is not by a DNA glycosylase.
Topics: 5-Methylcytosine; Cell Nucleus; Cytosine; DNA Glycosylases; HeLa Cells; Humans; N-Glycosyl Hydrolases; Polydeoxyribonucleotides; Polymers | 1995 |
A bisulfite method of 5-methylcytosine mapping that minimizes template degradation.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Modification Methylases; DNA Primers; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Templates, Genetic | 1995 |
The bulk chromatin structure of a murine transgene does not vary with its transcriptional or DNA methylation status.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; DNA; Gene Expression Regulation; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Restriction Mapping; Transcription, Genetic | 1995 |
Hereditary protein C deficiency associated with mutations in exon IX of the protein C gene.
Topics: 5-Methylcytosine; Adult; Base Sequence; Cytosine; Deamination; Exons; Female; Genes; Humans; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Protein C; Protein C Deficiency; Thrombophlebitis | 1994 |
5-methylcytosine attack by free radicals arising from bromotrichloromethane in a model system: structures of reaction products.
Topics: 5-Methylcytosine; Aerobiosis; Anaerobiosis; Bromotrichloromethane; Cytosine; DNA; Free Radicals; Gas Chromatography-Mass Spectrometry; Models, Chemical; Pentoxyl; Thymine | 1994 |
Abnormal methylation pattern in constitutive and facultative (X inactive chromosome) heterochromatin of ICF patients.
Topics: 5-Methylcytosine; Abnormalities, Multiple; Base Sequence; Case-Control Studies; Centromere; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Cytosine; DNA, Satellite; Face; Female; Heterochromatin; Humans; Immunologic Deficiency Syndromes; Infant; Male; Methylation; Molecular Sequence Data; Syndrome; X Chromosome | 1994 |
Interacisternal A-particle (IAP) genes show similar patterns of hypomethylation in established and primary mouse plasmacytomas.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Viral; Cytosine; DNA, Neoplasm; Genes, Intracisternal A-Particle; Methylation; Mice; Mice, Inbred BALB C; Mineral Oil; Plasmacytoma; Proviruses; Terpenes; Tumor Cells, Cultured | 1995 |
The use of 2-hydroperoxytetrahydrofuran as a reagent to sequence cytosine and to probe non-Watson-Crick DNA structures.
Topics: 5-Methylcytosine; Acetaldehyde; Base Sequence; Cytosine; DNA; DNA, Single-Stranded; Furans; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Indicators and Reagents; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Sequence Analysis, DNA | 1995 |
Formation of cyclobutane dimers and (6-4) photoproducts upon far-UV photolysis of 5-methylcytosine-containing dinucleotide monophosphates.
Topics: 5-Methylcytosine; Cytosine; Deoxycytidine; Dinucleoside Phosphates; Magnetic Resonance Spectroscopy; Photochemistry; Pyrimidine Dimers; Thymidine; Ultraviolet Rays | 1994 |
Substitution of 2-aminoadenine and 5-methylcytosine for adenine and cytosine in hybridization probes increases the sensitivity of DNA fingerprinting.
Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Base Sequence; Blotting, Southern; Cytosine; DNA; DNA Fingerprinting; DNA Primers; Humans; Molecular Sequence Data; Oligonucleotide Probes; Sensitivity and Specificity | 1994 |
New sites of methylcytosine-rich DNA detected on metaphase chromosomes.
Topics: 5-Methylcytosine; Chromosomes, Human; Cytosine; DNA; Female; Humans; Karyotyping; Male; Metaphase | 1994 |
Mutagenicity of nitric oxide is not caused by deamination of cytosine or 5-methylcytosine in double-stranded DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deamination; DNA; DNA Damage; DNA Repair; DNA, Bacterial; DNA, Neoplasm; Escherichia coli; Humans; Molecular Sequence Data; Mutagenesis; Mutagenicity Tests; Nitric Oxide; Plasmids | 1994 |
Hypomethylation of DNA: a possible nongenotoxic mechanism underlying the role of cell proliferation in carcinogenesis.
Topics: 5-Methylcytosine; Animals; Cell Division; Cytosine; DNA; Female; Liver Neoplasms, Experimental; Male; Methylation; Mice; Neoplasms; Proto-Oncogenes | 1993 |
Growth hormone gene structure in human pituitary somatotrophinomas: promoter region sequence and methylation studies.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes; Growth Hormone; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Pituitary Neoplasms; Promoter Regions, Genetic | 1994 |
Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Primers; DNA Replication; Enhancer Elements, Genetic; Gene Expression Regulation; Heterochromatin; Humans; Methylation; Mice; Molecular Sequence Data; MyoD Protein; Promoter Regions, Genetic; Restriction Mapping | 1994 |
High sensitivity mapping of methylated cytosines.
Topics: 5-Methylcytosine; Base Sequence; Cloning, Molecular; Cytosine; DNA Primers; DNA, Single-Stranded; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Denaturation; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Uracil | 1994 |
Secondary structure differences between normal and tumour DNA studied by UV-spectrophotometry.
Topics: 5-Methylcytosine; Animals; Base Composition; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Methylation; Nucleic Acid Conformation; Nucleic Acid Denaturation; Rats; Sarcoma, Experimental; Spectrophotometry, Ultraviolet; Temperature | 1993 |
Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis.
Topics: 5-Methylcytosine; Animals; Apolipoprotein A-I; Base Sequence; Cytosine; DNA-Binding Proteins; Epididymis; Gene Expression Regulation; Genetic Markers; Male; Methylation; Mice; Molecular Sequence Data; Octamer Transcription Factor-3; Phosphoglycerate Kinase; Sexual Maturation; Sperm Maturation; Spermatogenesis; Transcription Factors; Vas Deferens | 1994 |
Molecular cloning and expression of a novel hydroxymethylcytosine-specific restriction enzyme (PvuRts1I) modulated by glucosylation of DNA.
Topics: 5-Methylcytosine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytosine; DNA; DNA Restriction Enzymes; DNA, Viral; Genes, Bacterial; Glucose; Molecular Sequence Data; Substrate Specificity; T-Phages | 1994 |
An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome.
Topics: 5-Methylcytosine; Adult; Centromere; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytosine; DNA, Satellite; Embryo, Mammalian; Face; Female; Genetic Markers; Humans; Immunologic Deficiency Syndromes; Infant; Leukocytes; Male; Methylation; Placenta; Polymorphism, Restriction Fragment Length; Pregnancy; Repetitive Sequences, Nucleic Acid; Testis | 1993 |
Bipartite DNA recognition by the human Oct-2 POU domain: POUs-specific phosphate contacts are analogous to those of bacteriophage lambda repressor.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cytosine; DNA-Binding Proteins; Humans; Molecular Sequence Data; Octamer Transcription Factor-2; Oligodeoxyribonucleotides; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Structure-Activity Relationship; Transcription Factors; Viral Proteins; Viral Regulatory and Accessory Proteins | 1994 |
Effect of DNA cytosine methylation upon deamination-induced mutagenesis in a natural target sequence in duplex DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deamination; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Lac Operon; Molecular Sequence Data; Mutagenesis, Site-Directed; S-Adenosylmethionine | 1994 |
Methylation analysis on individual chromosomes: improved protocol for bisulphite genomic sequencing.
Topics: 5-Methylcytosine; Animals; Chromosomes; Cytosine; DNA; Genome; Methylation; Mice; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites | 1994 |
The Northrop hypothesis and the origins of a virus-induced enzyme.
Topics: 5-Methylcytosine; Cytosine; DNA, Viral; Escherichia coli; History, 20th Century; Hydroxymethyl and Formyl Transferases; Models, Biological; T-Phages; Transferases; United States | 1994 |
The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deamination; DNA; DNA-Cytosine Methylases; Hydrolysis; Kinetics; Methylation; Mutagenesis, Site-Directed; Mutation; Plasmids; Thermodynamics; Transformation, Genetic | 1994 |
An improved method for detection of 5-methylcytosine by PCR-based genomic sequencing.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Nucleic Acid Denaturation; Polymerase Chain Reaction; Sulfites | 1994 |
Effect of 5-methylcytosine on the structure and stability of DNA. Formation of triple-stranded concatenamers by overlapping oligonucleotides.
Topics: 5-Methylcytosine; Base Sequence; Calorimetry, Differential Scanning; Cytosine; DNA; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet; Temperature | 1994 |
Incision at DNA G.T mispairs by extracts of mammalian cells occurs preferentially at cytosine methylation sites and is not targeted by a separate G.T binding reaction.
Topics: 5-Methylcytosine; Animals; Base Sequence; Binding Sites; Cell Line; Cricetinae; Cytosine; DNA Repair; DNA Replication; Humans; Methylation; Molecular Sequence Data; Structure-Activity Relationship | 1993 |
Partial purification of a pea seed DNA-binding protein that specifically recognizes 5-methylcytosine.
Topics: 5-Methylcytosine; Ammonium Sulfate; Base Sequence; Cell Nucleus; Chemical Precipitation; Chromatography; Chromatography, Ion Exchange; Cytosine; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Fabaceae; Molecular Sequence Data; Molecular Weight; Plants, Medicinal; Seeds; Sepharose | 1993 |
[Intensification of genomic dactyloscopy by means of hybridization with modified oligonucleotides, forming duplexes with increased stability].
Topics: 2-Aminopurine; 5-Methylcytosine; Cytosine; DNA Fingerprinting; Nucleic Acid Hybridization; Oligonucleotides | 1993 |
Cytosine methylation enhances mitomycin C cross-linking.
Topics: 5-Methylcytosine; Base Sequence; Cross-Linking Reagents; Cytosine; Dinucleoside Phosphates; DNA; DNA Damage; Edetic Acid; Ferrous Compounds; Hydroxyl Radical; Methylation; Mitomycin; Molecular Sequence Data; Nucleic Acid Denaturation; Oligodeoxyribonucleotides | 1993 |
Dense nonsymmetrical DNA methylation resulting from repeat-induced point mutation in Neurospora.
Topics: 5-Methylcytosine; Base Sequence; Blotting, Southern; Cytosine; DNA Restriction Enzymes; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Genes, Fungal; Glutamate Dehydrogenase; Methylation; Molecular Sequence Data; Neurospora crassa; Point Mutation | 1993 |
Enzymic removal of 5-methylcytosine from DNA by a human DNA-glycosylase.
Topics: 5-Methylcytosine; Cell Nucleus; Cytosine; DNA; DNA Glycosylases; HeLa Cells; Humans; In Vitro Techniques; N-Glycosyl Hydrolases | 1993 |
Restriction endonuclease NciI is not blocked by CpG methylation.
Topics: 5-Methylcytosine; Cytosine; Deoxyribonucleases, Type II Site-Specific; Methylation; Substrate Specificity | 1993 |
High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Dosage Compensation, Genetic; Female; Fragile X Syndrome; Gene Expression Regulation; Humans; Male; Methylation; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Sequence Alignment; X Chromosome | 1993 |
Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Repair; Genes, p53; Guanine; Humans; Methylation; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase | 1994 |
Conformations of the alternating (C-T)n sequence under neutral and low pH.
Topics: 5-Methylcytosine; Base Composition; Base Sequence; Cytosine; DNA; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligoribonucleotides; Polydeoxyribonucleotides; Thymine | 1994 |
High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes: correlation with binding sites for transcription factors.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; Chromosome Mapping; Cytosine; DNA; DNA Primers; Female; Fibroblasts; Hominidae; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Mammals; Methylation; Molecular Sequence Data; Polymerase Chain Reaction; Transcription Factors; X Chromosome | 1994 |
Comparative analysis of the methylation status of the 5' flanking region of Ha-ras in B6C3F1, C3H/He and C57BL/6 mouse liver.
Topics: 5-Methylcytosine; Animals; Base Sequence; Blotting, Southern; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Male; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Oligonucleotide Probes; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Analysis, DNA | 1993 |
HhaI methyltransferase flips its target base out of the DNA helix.
Topics: 5-Methylcytosine; Bacterial Proteins; Base Sequence; Binding Sites; Crystallography, X-Ray; Cytosine; DNA; DNA-Binding Proteins; DNA-Cytosine Methylases; Haemophilus; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1994 |
Sequence analysis of oligodeoxyribonucleotides.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cattle; Chromatography, Thin Layer; Cytosine; DNA Nucleotidylexotransferase; Endodeoxyribonucleases; Indicators and Reagents; Intestines; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Polynucleotide 5'-Hydroxyl-Kinase; Spleen | 1994 |
Arabidopsis thaliana DNA methylation mutants.
Topics: 5-Methylcytosine; Arabidopsis; Centromere; Crosses, Genetic; Cytosine; DNA; DNA, Ribosomal; Genes, Plant; Genes, Recessive; Methylation; Mutation; Phenotype | 1993 |
Developmental differences in methylation of human Alu repeats.
Topics: 5-Methylcytosine; Age Factors; Base Sequence; Blotting, Southern; Cytosine; Female; Gene Expression Regulation; HeLa Cells; Humans; Male; Methylation; Molecular Sequence Data; Placenta; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Spermatozoa; Spleen | 1993 |
Isolation and characterization of an Escherichia coli strain with a high frequency of C-to-T mutations at 5-methylcytosines.
Topics: 5-Methylcytosine; Base Sequence; Chromosome Mapping; Cytosine; DNA Repair; Escherichia coli; Genes, Bacterial; Lac Operon; Molecular Sequence Data; Mutagenesis; Phenotype; Suppression, Genetic; Thymine | 1993 |
Modified-cytosine restriction-system-induced recombinant cloning artefacts in Escherichia coli.
Topics: 5-Methylcytosine; Base Sequence; Cloning, Molecular; Cytosine; Dinucleoside Phosphates; DNA Restriction Enzymes; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Genotype; Mutation; Plasmids; Recombination, Genetic; Tetracycline Resistance | 1993 |
Quantitation of 5-methylcytosine by one-dimensional high-performance thin-layer chromatography.
Topics: 5-Methylcytosine; Animals; CHO Cells; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Cricetulus; Cytosine; DNA; Exonucleases; Hydrolysis; Micrococcal Nuclease; Nucleosides; Polynucleotide 5'-Hydroxyl-Kinase | 1993 |
Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; Gene Rearrangement, B-Lymphocyte; Genes, Immunoglobulin; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Recombination, Genetic; Restriction Mapping | 1993 |
Effect of 5-methylcytosine as a neighboring base on methylation of DNA guanine by N-methyl-N-nitrosourea.
Topics: 5-Methylcytosine; Autoradiography; Base Sequence; Cytosine; DNA; DNA Damage; Guanine; Humans; Methylation; Methylnitrosourea; Molecular Sequence Data | 1993 |
Characterization of DBPm, a plant protein that binds to DNA containing 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cell Nucleus; Cytosine; DNA; DNA-Binding Proteins; Kinetics; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Plant Proteins; Plants | 1993 |
Restriction endonuclease cleavage of 5-methyl-deoxycytosine hemimethylated DNA at high enzyme-to-substrate ratios.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Molecular Sequence Data; Substrate Specificity | 1993 |
CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene.
Topics: 5-Methylcytosine; Base Sequence; Cell Line; Consensus Sequence; Cytosine; Gene Expression; Genes, Retinoblastoma; Humans; In Vitro Techniques; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Retinoblastoma Protein; RNA, Messenger; Transcription Factors | 1993 |
Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Humans; Methylation; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Repressor Proteins; RNA Polymerase III; Templates, Genetic; Transcription, Genetic | 1993 |
The methylation status of the major breakpoint cluster region in human leukemia cells, including Philadelphia chromosome-positive cells, is linked to the lineage of hematopoietic cells.
Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Restriction Mapping; Translocation, Genetic; Tumor Cells, Cultured | 1993 |
Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation.
Topics: 5-Methylcytosine; Cytosine; DNA; Fungi; Gene Expression Regulation, Fungal; Genes, Fungal; Meiosis; Methylation; Repetitive Sequences, Nucleic Acid; Restriction Mapping; RNA, Messenger; Transcription, Genetic | 1993 |
Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Nucleus; Cell-Free System; Chick Embryo; Cytosine; DNA; DNA Polymerase I; DNA Repair; Gene Expression Regulation; In Vitro Techniques; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides | 1993 |
Leptospira genomes are modified at 5'-GTAC.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA, Bacterial; Leptospira; Methylation; Restriction Mapping | 1993 |
Detecting differences in 5-methylcytosine using restriction enzyme isoschizomers: an endogenous control for complete digestion.
Topics: 5-Methylcytosine; Animals; Base Sequence; Blotting, Southern; Cell Line; Cytosine; DNA Restriction Enzymes; DNA, Mitochondrial; Humans; Mammals; Multiple Myeloma; Restriction Mapping; Thymidine Kinase; Tumor Cells, Cultured | 1995 |
Crystal structure of the A-DNA decamer d(CCIGGCCm5CGG) at 1.6 A showing the unexpected wobble I.m5C base pair.
Topics: 5-Methylcytosine; Base Composition; Base Sequence; Biophysical Phenomena; Biophysics; Crystallography, X-Ray; Cytosine; DNA; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Water | 1995 |
[Changes in methylation of tumor cells: a new in situ quantitative approach on interphase nuclei and chromosomes].
Topics: 5-Methylcytosine; Cell Nucleus; Chromosome Banding; Chromosomes, Human; Cytosine; DNA; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Interphase; Metaphase; Methylation; Sensitivity and Specificity; Tumor Cells, Cultured | 1995 |
DNA methylation in mycobacteria: absence of methylation at GATC (Dam) and CCA/TGG (Dcm) sequences.
Topics: 5-Methylcytosine; Adenosine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; DNA, Bacterial; Methylation; Molecular Sequence Data; Mycobacterium; Mycobacterium tuberculosis; Site-Specific DNA-Methyltransferase (Adenine-Specific); Species Specificity; Substrate Specificity; Virulence | 1995 |
Effects of novel 3,4-bisphenylhex(3)enes on cell proliferation in malignant and normal cells.
Topics: 5-Methylcytosine; Alkenes; Animals; Antineoplastic Agents; Carcinoma; Cell Division; Cell Line, Transformed; Cricetinae; Cytosine; HT29 Cells; Humans; Infant, Newborn; Keratinocytes; Mesocricetus; Mice | 1996 |
DNA mismatch repair and DNA methylation in adult brain neurons.
Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Brain; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Repair; Liver; Methylation; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Organ Specificity; Rats; Thymine; Thymus Gland; Uracil | 1996 |
5-Methylcytosine attack by hydroxyl free radicals and during carbon tetrachloride promoted liver microsomal lipid peroxidation: structure of reaction products.
Topics: 5-Methylcytosine; Animals; Carbon Tetrachloride; Cytosine; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydantoins; Hydrogen Peroxide; Hydroxyl Radical; Iron; Lipid Peroxidation; Male; Microsomes, Liver; Molecular Structure; Rats; Rats, Sprague-Dawley; Ultraviolet Rays | 1996 |
Methylation pattern of Activator transposase binding sites in maize endosperm.
Topics: 5-Methylcytosine; Base Sequence; Chromatids; Cytosine; DNA; DNA Primers; DNA Transposable Elements; Methylation; Molecular Sequence Data; Recombination, Genetic; Sulfites; Zea mays | 1996 |
DNA methylation of the X chromosomes of the human female: an in situ semi-quantitative analysis.
Topics: 5-Methylcytosine; Animals; Antibodies, Monoclonal; Cells, Cultured; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Dosage Compensation, Genetic; Female; Fibroblasts; Fluorescent Antibody Technique, Indirect; Heterochromatin; Humans; Image Processing, Computer-Assisted; Karyotyping; Lymphocytes; Methylation; Microscopy, Fluorescence; Prohibitins; Rabbits; Sex Chromosome Aberrations; X Chromosome | 1996 |
Nucleic acid composition of bone marrow mononuclear cells in cobalamin deficiency.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Anemia, Megaloblastic; Artifacts; Bone Marrow; Chromatography, High Pressure Liquid; Cytosine; Deamination; DNA; DNA Glycosylases; Female; Humans; Male; Methionine; Methylation; Middle Aged; N-Glycosyl Hydrolases; Reproducibility of Results; Uracil; Uracil-DNA Glycosidase; Vitamin B 12 Deficiency | 1996 |
mCCG methylation in angiosperms.
Topics: 5-Methylcytosine; Arabidopsis; Base Sequence; Cytosine; Genome, Plant; Methylation; Molecular Sequence Data; Nicotiana; Pisum sativum; Plants; Plants, Toxic; Restriction Mapping; Species Specificity; Triticum | 1996 |
Demethylation-induced developmental pleiotropy in Arabidopsis.
Topics: 5-Methylcytosine; Arabidopsis; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Plant; Gene Expression Regulation, Plant; Genes, Plant; Methylation; Phenotype; Plants, Genetically Modified; Repetitive Sequences, Nucleic Acid; RNA, Antisense | 1996 |
Methylation of coding region alone inhibits gene expression in plant protoplasts.
Topics: 5-Methylcytosine; Base Sequence; Cells, Cultured; Cytosine; Exons; Gene Expression Regulation, Plant; Genes, Plant; Methylation; Molecular Sequence Data; Plants; Promoter Regions, Genetic | 1996 |
Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development.
Topics: 5-Methylcytosine; Arabidopsis; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Antisense; Gene Expression Regulation, Developmental; Methylation; Phenotype; Plants, Genetically Modified; RNA, Messenger; RNA, Plant | 1996 |
Oligonucleotides containing 2-aminoadenine and 5-methylcytosine are more effective as primers for PCR amplification than their nonmodified counterparts.
Topics: 2-Aminopurine; 5-Methylcytosine; Base Sequence; Cytosine; DNA Primers; Molecular Sequence Data; Polymerase Chain Reaction | 1996 |
Distribution of 5-methylcytosine-rich regions in the metaphase chromosomes of Vicia faba.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Chromosome Banding; Chromosome Mapping; Chromosomes; Cytosine; Fabaceae; Genes, Plant; Immunohistochemistry; Metaphase; Methylation; Plants, Medicinal | 1996 |
Miscoding properties of isoguanine (2-oxoadenine) studied in an AMV reverse transcriptase in vitro system.
Topics: 5-Methylcytosine; Adenosine; Avian Myeloblastosis Virus; Base Composition; Cytosine; Deoxyribonucleotides; Guanosine; Kinetics; Polydeoxyribonucleotides; RNA-Directed DNA Polymerase; Substrate Specificity; Templates, Genetic; Thymine | 1996 |
Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Azacitidine; Cells, Cultured; Centromere; Chromosomes, Human; Cytosine; DNA Methylation; Heterochromatin; Humans; Karyotyping; Lymphocytes; Male | 1996 |
Photochemical deamination and demethylation of 5-methylcytosine.
Topics: 5-Methylcytosine; Amination; Cytosine; Dealkylation; Deamination; DNA; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Photochemistry; Spectrophotometry, Ultraviolet; Tritium; Ultraviolet Rays | 1996 |
Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase.
Topics: 5-Methylcytosine; Base Composition; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Repair; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Escherichia coli; Humans; Hydrogen Bonding; Kinetics; Recombinant Proteins; Substrate Specificity | 1996 |
CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease.
Topics: 5-Methylcytosine; Anemia, Aplastic; Burkitt Lymphoma; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; DNA, Neoplasm; DNA, Viral; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Ghana; Herpesviridae Infections; Herpesvirus 4, Human; Hodgkin Disease; Immunocompromised Host; Immunodominant Epitopes; Immunologic Surveillance; Lymphoma, B-Cell; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Tumor Virus Infections; Virus Latency | 1996 |
Counteracting the mutagenic effect of hydrolytic deamination of DNA 5-methylcytosine residues at high temperature: DNA mismatch N-glycosylase Mig.Mth of the thermophilic archaeon Methanobacterium thermoautotrophicum THF.
Topics: 5-Methylcytosine; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytosine; Deamination; DNA Glycosylases; DNA Repair; DNA, Bacterial; Genes, Bacterial; Hot Temperature; Methanobacterium; Molecular Sequence Data; N-Glycosyl Hydrolases; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Recombinant Fusion Proteins; Substrate Specificity; Uracil-DNA Glycosidase | 1996 |
DNA methyltransferase in normal and Dnmtn/Dnmtn mouse embryos.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Cytoplasm; Cytosine; Decidua; DNA (Cytosine-5-)-Methyltransferases; Embryo Implantation; Female; Fetal Proteins; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Developmental; Gestational Age; Methylation; Mice; Mice, Mutant Strains; Nerve Tissue Proteins; Nervous System | 1996 |
AZT-induced hypermethylation of human thymidine kinase gene in the absence of total DNA hypermethylation.
Topics: 5-Methylcytosine; Antiviral Agents; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; Drug Resistance; Exons; Humans; Polymerase Chain Reaction; Thymidine Kinase; Zidovudine | 1996 |
Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.
Topics: 5-Methylcytosine; Animals; CHO Cells; CpG Islands; Cricetinae; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; Molecular Sequence Data; Replication Origin; Ribosomal Proteins; Sulfites | 1997 |
Hypermethylation of calcitonin gene regulatory sequences in human breast cancer as revealed by genomic sequencing.
Topics: 5-Methylcytosine; Breast Neoplasms; Calcitonin; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; DNA, Neoplasm; Female; Fibroadenoma; Gene Expression Regulation, Neoplastic; Humans; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA | 1996 |
Solid phase synthesis and restriction endonuclease cleavage of oligodeoxynucleotides containing 5-(hydroxymethyl)-cytosine.
Topics: 5-Methylcytosine; Cytosine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; DNA-Cytosine Methylases; Molecular Structure; Oligodeoxyribonucleotides | 1997 |
5-Methylcytosine is not a mutation hot spot in nondividing Escherichia coli.
Topics: 5-Methylcytosine; Coliphages; Cytosine; Deamination; DNA Methylation; DNA Repair; DNA, Viral; Escherichia coli; Kanamycin Resistance; Lysogeny; Mutagenesis; Point Mutation; Temperature | 1997 |
Imprinted segments in the human genome: different DNA methylation patterns in the Prader-Willi/Angelman syndrome region as determined by the genomic sequencing method.
Topics: 5-Methylcytosine; Angelman Syndrome; Autoantigens; Chromosomes, Human, Pair 15; Cloning, Molecular; CpG Islands; Cytosine; Dinucleoside Phosphates; DNA Methylation; Female; Genomic Imprinting; Humans; Male; Plasmids; Polymerase Chain Reaction; Prader-Willi Syndrome; Promoter Regions, Genetic; Restriction Mapping; Ribonucleoproteins, Small Nuclear; Sequence Analysis, DNA; Sequence Deletion; snRNP Core Proteins; Sulfites | 1997 |
Use of a single sequencing termination reaction to distinguish between cytosine and 5-methylcytosine in bisulfite-modified DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Methylation; DNA Primers; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites | 1997 |
Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spermine | 1997 |
Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.
Topics: 5-Methylcytosine; Animals; Base Sequence; Binding Sites; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; DNA, Single-Stranded; Kinetics; Methyltransferases; Mice; Molecular Sequence Data; Oligonucleotides; Recombinant Proteins | 1997 |
Lack of correlation between binding of EcoRII methyltransferase to DNA duplexes containing mismatches and the promotion of C to T mutations.
Topics: 5-Methylcytosine; Binding Sites; Cytosine; DNA Methylation; DNA Repair; DNA-Cytosine Methylases; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Mutation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Point Mutation | 1997 |
5-methylcytosine is present in the 5' flanking region of Ha-ras in mouse liver and increases with ageing.
Topics: 5-Methylcytosine; Aging; Animals; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA Restriction Enzymes; Genes, ras; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction | 1997 |
Rapid and sensitive high-performance liquid chromatographic analysis of halogenopyrimidines in plasma.
Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Bromouracil; Chromatography, High Pressure Liquid; Cytosine; Flucytosine; Fluorouracil; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Uracil | 1997 |
Developmental changes in DNA methylation of the two tobacco pollen nuclei during maturation.
Topics: 5-Methylcytosine; Antibodies; Antibody Specificity; Cell Nucleus; Cytosine; DNA Methylation; DNA, Plant; Meiosis; Microscopy, Confocal; Mitosis; Nicotiana; Oligodeoxyribonucleotides; Plants, Toxic; Pollen | 1997 |
Triplex formation at physiological pH: comparative studies on DNA triplexes containing 5-Me-dC tethered at N4 with spermine and tetraethyleneoxyamine.
Topics: 5-Methylcytosine; Cytosine; DNA; Hot Temperature; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Polyethylene Glycols; Salts; Spermine | 1997 |
Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA.
Topics: 5-Methylcytosine; Animals; Base Composition; Cell Line; Cytosine; DNA; DNA Methylation; DNA Primers; Genes, Retinoblastoma; Humans; Mice; Polymerase Chain Reaction; Sensitivity and Specificity; Sulfites | 1997 |
Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases.
Topics: 5-Methylcytosine; Codon; Cytosine; Genes, p53; Humans; Keratinocytes; Methylation; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Sunlight | 1997 |
Base composition of DNA from glomalean fungi: high amounts of methylated cytosine.
Topics: 5-Methylcytosine; Base Composition; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; DNA, Fungal; Fungi; Hot Temperature; Nucleic Acid Denaturation; Spores, Fungal | 1997 |
Reliable detection of DNA CpG methylation profiles by the isoschizomers MspI/HpaII using oligonucleotide stimulators.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; DNA, Viral; Polymerase Chain Reaction; Sequence Analysis, DNA; Simian virus 40 | 1997 |
Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine.
Topics: 5-Methylcytosine; Aminopyridines; Base Composition; Cytosine; DNA Footprinting; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Polydeoxyribonucleotides; Substrate Specificity | 1997 |
Cytosine methylation enhances DNA damage produced by groove binding and intercalating enediynes: studies with esperamicins A1 and C.
Topics: 5-Methylcytosine; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cytosine; DNA Damage; DNA Methylation; Enediynes; Intercalating Agents | 1997 |
Cytosine methylation targetted to pre-determined sequences.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Base Sequence; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Molecular Sequence Data; Recombinant Fusion Proteins; Zinc Fingers | 1997 |
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Bacterial Proteins; Chromosome Mapping; Chromosomes, Human, Pair 10; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Complementary; Evolution, Molecular; Fetal Proteins; Fungal Proteins; Gene Expression; Gene Targeting; Humans; Isoenzymes; Mice; Molecular Sequence Data; Schizosaccharomyces; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Stem Cells | 1998 |
Does DNA methylation control transposition of selfish elements in the germline?
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA Transposable Elements; Drosophila melanogaster; Embryo, Mammalian; Embryo, Nonmammalian; Germ Cells; Humans; Mammals; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Retroviridae | 1997 |
Computer-assisted analysis of methylation status of individual interphase nuclei in human cultured cells.
Topics: 5-Methylcytosine; Cell Line; Cell Nucleus; Cytosine; DNA Methylation; DNA Probes; DNA, Satellite; Female; Fluorescent Antibody Technique, Indirect; Heterochromatin; Humans; Image Processing, Computer-Assisted; In Situ Hybridization, Fluorescence; Interphase; Lymphocytes; Male; Metaphase; Software | 1998 |
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line, Transformed; Cellular Senescence; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation; Genes, p16; Genes, p53; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome | 1998 |
Recognition of DNA methylation by zinc fingers.
Topics: 5-Methylcytosine; Amino Acid Sequence; Base Sequence; Binding Sites; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Transcription Factors; Zinc Fingers | 1998 |
Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage.
Topics: 5-Methylcytosine; Base Sequence; Camptothecin; Cytosine; DNA; DNA Topoisomerases, Type I; Humans; Molecular Sequence Data; Structure-Activity Relationship | 1998 |
Hydration and recognition of methylated CpG steps in DNA.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Crystallography, X-Ray; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; Hydrogen Bonding; Magnesium; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Water | 1998 |
Altered patterns of DNA methylation on chromosomes from leukemia cell lines: identification of 5-methylcytosines by indirect immunodetection.
Topics: 5-Methylcytosine; Adult; Animals; Antibodies, Monoclonal; Chromosomes, Human; Cytosine; DNA Methylation; DNA Restriction Enzymes; Female; Fluorescent Antibody Technique, Indirect; Humans; Male; Mice; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Telomere; Tumor Cells, Cultured; Ultraviolet Rays | 1998 |
Chromosome methylation patterns during mammalian preimplantation development.
Topics: 5-Methylcytosine; Animals; Antibodies, Monoclonal; Cytosine; DNA Methylation; Embryonic and Fetal Development; Embryonic Development; Female; Humans; Male; Mammals; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy | 1998 |
Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae.
Topics: 5-Methylcytosine; Adenine; Bacterial Proteins; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Fungal Proteins; Humans; N-Glycosyl Hydrolases; Oligonucleotides; Purines; Pyridines; Saccharomyces cerevisiae | 1998 |
Structure and DNA methylation pattern of partially heterochromatinised endosperm nuclei in Gagea lutea (Liliaceae).
Topics: 5-Methylcytosine; Animals; Antibodies, Monoclonal; Cell Nucleus; Cytosine; DNA Methylation; DNA, Plant; Heterochromatin; Interphase; Liliaceae; Mice; Mitosis | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice.
Topics: 5-Methylcytosine; Adenoma; Animals; Carcinogens; Cytosine; Dichloroacetic Acid; DNA Methylation; Female; Liver; Liver Neoplasms, Experimental; Mice; Trichloroacetic Acid | 1998 |
Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats.
Topics: 5-Methylcytosine; Animals; Caseins; Choline Deficiency; Cytosine; Dietary Proteins; DNA; DNA Methylation; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weaning | 1998 |
Mapping of 5-methylcytosine residues in Nicotiana tabacum 5S rRNA genes by genomic sequencing.
Topics: 5-Methylcytosine; Adenine; Base Sequence; Consensus Sequence; Cytosine; DNA Methylation; DNA, Plant; Genes, Plant; Molecular Sequence Data; Nicotiana; Plants, Toxic; Polymerase Chain Reaction; RNA, Ribosomal, 5S; Sequence Analysis, DNA | 1998 |
Urea improves efficiency of bisulphite-mediated sequencing of 5'-methylcytosine in genomic DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA, Single-Stranded; Genes, MDR; Genome, Human; Humans; Indicators and Reagents; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Urea | 1998 |
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells.
Topics: 5-Methylcytosine; BRCA1 Protein; Breast Neoplasms; Cell Line; CpG Islands; Cytosine; DNA Methylation; Female; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts.
Topics: 5-Methylcytosine; Artifacts; CpG Islands; Cytosine; DNA Methylation; Sequence Analysis, DNA; Sulfites | 1998 |
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured | 1998 |
Reduced levels of poly(ADP-ribosyl)ation result in chromatin compaction and hypermethylation as shown by cell-by-cell computer-assisted quantitative analysis.
Topics: 3T3 Cells; 5-Methylcytosine; Animals; Benzamides; Cytosine; DNA Methylation; Enzyme Inhibitors; Heterochromatin; Image Processing, Computer-Assisted; Mice; Poly(ADP-ribose) Polymerase Inhibitors | 1999 |
Role of DNA 5-methylcytosine transferase in cell transformation by fos.
Topics: 5-Methylcytosine; Acetylation; Animals; Cell Size; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, fos; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Proto-Oncogene Proteins c-fos; Rats; Transcription, Genetic; Transfection | 1999 |
5-Methylcytosine in CpG sites and the reactivity of nearest neighboring guanines toward the carcinogen aflatoxin B1-8,9-epoxide.
Topics: 5-Methylcytosine; Aflatoxin B1; Carcinogens; Cytosine; Gene Expression Regulation, Neoplastic; Genes, p53; Guanine; Humans; Oligonucleotides | 1999 |
Localization of 5-methylcytosine in metaphase chromosomes of diploid and triploid pacu fish, Piaractus mesopotamicus (pisces, characiformes).
Topics: 5-Methylcytosine; Animals; Chromosome Mapping; Cyprinodontiformes; Cytosine; Diploidy; DNA Methylation; Gene Dosage; In Situ Hybridization, Fluorescence; Metaphase; Polyploidy | 1998 |
Substrate recognition by the Pvu II endonuclease: binding and cleavage of CAG5mCTG sites.
Topics: 5-Methylcytosine; Binding Sites; Binding, Competitive; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Footprinting; DNA Methylation; DNA-Cytosine Methylases; Oligodeoxyribonucleotides; Substrate Specificity | 1999 |
CpG doublets, CpG islands and Alu repeats in long human DNA sequences from different isochore families.
Topics: 5-Methylcytosine; Alu Elements; Amino Acid Sequence; Codon; CpG Islands; Cytosine; Databases, Factual; DNA; Guanine; Humans; Pseudogenes; Statistics as Topic | 1998 |
Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli.
Topics: 5-Methylcytosine; Amino Acid Sequence; Cloning, Molecular; Cytosine; DNA Methylation; Escherichia coli; Gene Expression; Genes, Bacterial; Magnesium; Methyltransferases; Molecular Sequence Data; Open Reading Frames; Recombinant Proteins; RNA, Ribosomal, 16S; Substrate Specificity | 1999 |
Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential.
Topics: 5-Methylcytosine; Carcinoma; Cell Transformation, Neoplastic; Centromere; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Cytosine; DNA Methylation; DNA, Neoplasm; DNA, Satellite; Female; Humans; Ovarian Neoplasms | 1999 |
Decrease with age in methylcytosines in the promoter region of receptor for advanced glycated end products (RAGE) gene in autopsy human cortex.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Aging; Base Sequence; Brain Chemistry; Cerebral Cortex; Cytosine; DNA Methylation; DNA Probes; Female; Glycation End Products, Advanced; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transcription, Genetic | 1999 |
Base pairing of anhydrohexitol nucleosides with 2,6-diaminopurine, 5-methylcytosine and uracil asbase moiety.
Topics: 2-Aminopurine; 5-Methylcytosine; Arabinonucleosides; Base Pairing; Cytosine; Models, Molecular; Nucleic Acid Denaturation; Nucleosides; Oligonucleotides; Purine Nucleosides; Pyrimidine Nucleosides; Sugar Alcohols; Uracil | 1999 |
S1 SINE retroposons are methylated at symmetrical and non-symmetrical positions in Brassica napus: identification of a preferred target site for asymmetrical methylation.
Topics: 5-Methylcytosine; Brassica; Cytosine; DNA Methylation; DNA, Plant; In Situ Hybridization, Fluorescence; Short Interspersed Nucleotide Elements; Sulfites | 1999 |
Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.
Topics: 5-Methylcytosine; Cloning, Molecular; Cytosine; Endoribonucleases; Escherichia coli; Gene Deletion; Hydroxymethyl and Formyl Transferases; Methylation; Methyltransferases; Ribonuclease T1; RNA, Ribosomal, 16S; S-Adenosylmethionine; Single-Strand Specific DNA and RNA Endonucleases; Substrate Specificity | 1999 |
Relationship between amount of esterase and gene copy number in insecticide-resistant Myzus persicae (Sulzer).
Topics: 5-Methylcytosine; Animals; Aphids; Binding, Competitive; Blotting, Southern; Carboxylesterase; Cytosine; DNA Methylation; DNA Primers; DNA, Complementary; Electrophoresis, Gel, Pulsed-Field; Esterases; Gene Amplification; Gene Dosage; Gene Expression Regulation, Enzymologic; Genotype; Insect Proteins; Insecticide Resistance; Introns; Polymerase Chain Reaction | 1999 |
Novel procedure for the detection of 5-methylcytosine.
Topics: 5-Methylcytosine; Base Composition; Cytosine; DNA; DNA Methylation; DNA Modification Methylases; Genetic Techniques; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Sulfites | 1998 |
Sensitivity of the restriction endonucleases HaeIII, BsrI, EaeI and CfrI to cytosine N4-methylation.
Topics: 5-Methylcytosine; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA-Cytosine Methylases; Plasmids; Restriction Mapping | 1998 |
DNA methylation is a reversible biological signal.
Topics: 5-Methylcytosine; Base Sequence; Cell Line; Cell Nucleus; Cytosine; Dinucleoside Phosphates; DNA Methylation; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Methanol; Oligodeoxyribonucleotides; Oxidoreductases, O-Demethylating; Signal Transduction; Substrate Specificity | 1999 |
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.
Topics: 5-Methylcytosine; Adenocarcinoma; Chondroitin Sulfate Proteoglycans; Cloning, Molecular; Colorectal Neoplasms; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; DNA, Ribosomal; Exons; Eye Proteins; Genes, p16; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Humans; Lectins, C-Type; Paired Box Transcription Factors; PAX6 Transcription Factor; Polymerase Chain Reaction; Repressor Proteins; RNA, Ribosomal; Subtraction Technique; Transcription Factors; Tubulin; Versicans | 1999 |
Bisulfite sequencing protocol displays both 5-methylcytosine and N4-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Methylation; DNA Primers; DNA, Bacterial; Escherichia coli; Plasmids; Sequence Analysis, DNA; Sulfites | 1999 |
Growth phase-dependent regulation of Vsr endonuclease may contribute to 5-methylcytosine mutational hot spots in Escherichia coli.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Endodeoxyribonucleases; Escherichia coli; Gene Expression Regulation, Bacterial; Mutation | 1999 |
Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Aging; Amyloid beta-Protein Precursor; Autopsy; Base Composition; Base Sequence; Cerebral Cortex; Cytosine; DNA Methylation; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid | 1999 |
Impact of C5-cytosine methylation on the solution structure of d(GAAAACGTTTTC)2. An NMR and molecular modelling investigation.
Topics: 5-Methylcytosine; Base Sequence; CpG Islands; Cytosine; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Solutions | 1999 |
The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.
Topics: 5-Methylcytosine; Base Pair Mismatch; Cytosine; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Humans; Mutagenesis; N-Glycosyl Hydrolases; Open Reading Frames; Point Mutation; Substrate Specificity; Thymine; Thymine DNA Glycosylase | 1999 |
Quantification of 5-methylcytosine in DNA by the chloroacetaldehyde reaction.
Topics: 5-Methylcytosine; Acetaldehyde; Borohydrides; Chemical Precipitation; Chromatography, High Pressure Liquid; Cinnamates; Cytosine; DNA; DNA Methylation; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Hygromycin B; Purines; Silver Nitrate; Solutions; Spectrometry, Fluorescence; Sulfites | 1999 |
Involvement of 5-methylcytosine in sunlight-induced mutagenesis.
Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Mutational Analysis; Escherichia coli Proteins; Fibroblasts; Genes, p53; Humans; Lac Repressors; Mice; Mice, Transgenic; Models, Genetic; Molecular Sequence Data; Mutagenesis; Mutation; Pyrimidine Dimers; Repressor Proteins; Skin Neoplasms; Sunlight; Transgenes; Ultraviolet Rays | 1999 |
Methylation levels of normal and chronic lymphocytic leukemia B lymphocytes: computer-assisted quantitative analysis of anti-5-methylcytosine antibody binding to individual nuclei.
Topics: 5-Methylcytosine; Antibodies; B-Lymphocytes; Binding Sites, Antibody; Cell Nucleus; Cytosine; DNA Methylation; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell | 1999 |
5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine.
Topics: 5-Methylcytosine; Azacitidine; Chromosome Mapping; Cytosine; DNA Methylation; DNA, Plant; DNA, Ribosomal; Edible Grain; Genome, Plant; Plant Roots; Secale; Triticum | 1999 |
[DNA methyltransferases for detection of the level of methylation of cytosine in the DNA CCWGG sequence].
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Escherichia coli | 1999 |
[Changes in the level of DNA minor bases in salivary gland inflammation and its correction with antioxidants].
Topics: 5-Methylcytosine; Animals; Antioxidants; Carrageenan; Cytosine; DNA; Drug Evaluation, Preclinical; Guanine; Guinea Pigs; Sialadenitis | 1999 |
5-methylcytosine at HpaII sites in p53 is not hypermutable after UVC irradiation.
Topics: 5-Methylcytosine; Codon; CpG Islands; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; Humans; Mutation; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays; Yeasts | 1999 |
Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos.
Topics: 5-Methylcytosine; Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Embryo, Nonmammalian; Gastrula; Gene Expression Regulation, Developmental; Gene Silencing; Humans; In Vitro Techniques; Mice; Microinjections; Reverse Transcriptase Polymerase Chain Reaction; RNA, Antisense; T-Box Domain Proteins; Transcriptional Activation; Xenopus laevis; Xenopus Proteins | 2000 |
Demethylation of the zygotic paternal genome.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Female; Genome; Male; Mice; Sex Characteristics; Zygote | 2000 |
Synthesis and hybridization properties of DNA-PNA chimeras carrying 5-bromouracil and 5-methylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Bromouracil; Cytosine; DNA; Magnetic Resonance Spectroscopy; Nucleic Acid Hybridization; Peptide Nucleic Acids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2000 |
SINE retroposons can be used in vivo as nucleation centers for de novo methylation.
Topics: 5-Methylcytosine; Brassica; Cytosine; DNA Methylation; DNA Replication; DNA, Plant; Genome, Plant; Models, Genetic; Retroelements; Sequence Analysis, DNA; Short Interspersed Nucleotide Elements | 2000 |
Methyl-specific DNA binding by McrBC, a modification-dependent restriction enzyme.
Topics: 5-Methylcytosine; Allosteric Site; Bacterial Proteins; Base Sequence; Binding, Competitive; Coenzymes; Cytosine; Deoxyribonuclease I; DNA Footprinting; DNA Methylation; DNA Restriction Enzymes; DNA-Binding Proteins; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Guanosine Triphosphate; Hydrolysis; Magnesium; Models, Biological; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Binding; Substrate Specificity; Thermodynamics | 2000 |
Methyl-deficient mammalian transfer RNA: II. Homologous methylation in vitro of liver tRNA from normal and ethionine-fed rats: ethionine effect on 5-methyl-cytidine synthesis in vivo.
Topics: 5-Methylcytosine; Adenosine; Administration, Oral; Animals; Cadaverine; Cytosine; Ethionine; Liver; Magnesium; Methylation; Nucleic Acid Conformation; Rats; RNA, Transfer; tRNA Methyltransferases | 1974 |
CpG methylation is maintained in human cancer cells lacking DNMT1.
Topics: 5-Methylcytosine; Blotting, Southern; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, p16; Humans; Tumor Cells, Cultured | 2000 |
Influence of sequence-dependent cytosine protonation and methylation on DNA triplex stability.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Methylation; Hydrogen-Ion Concentration; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons | 2000 |
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.
Topics: 5-Methylcytosine; Animals; Animals, Genetically Modified; Base Sequence; Cloning, Molecular; Cytosine; Dinucleoside Phosphates; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Drosophila melanogaster; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic and Fetal Development; Mammals; Molecular Sequence Data; Polymerase Chain Reaction; Restriction Mapping; Stem Cells | 2000 |
Combined effects of okadaic acid and cadmium on lipid peroxidation and DNA bases modifications (m5dC and 8-(OH)-dG) in Caco-2 cells.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Caco-2 Cells; Cadmium; Carcinogens; Chromatography, High Pressure Liquid; Cytosine; Deoxyguanosine; DNA; Drug Synergism; Enzyme Inhibitors; Humans; Leucine; Lipid Peroxidation; Malondialdehyde; Okadaic Acid; Protein Synthesis Inhibitors | 2000 |
Short TpA-rich segments of the zeta-eta region induce DNA methylation in Neurospora crassa.
Topics: 5-Methylcytosine; AT Rich Sequence; Base Composition; Base Sequence; Blotting, Southern; Cytosine; DNA Methylation; DNA, Fungal; Endodeoxyribonucleases; Molecular Sequence Data; Mutation; Neurospora crassa; Plasmids; Regulatory Sequences, Nucleic Acid; Reproducibility of Results; Sequence Deletion; Transformation, Genetic | 2000 |
Through a glass, darkly: reflections of mutation from lacI transgenic mice.
Topics: 5-Methylcytosine; Aging; Animals; Bacterial Proteins; Brain; Cell Division; CpG Islands; Cytosine; Deamination; DNA Methylation; DNA Mutational Analysis; Escherichia coli Proteins; Gene Frequency; Lac Repressors; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Repressor Proteins; Species Specificity; Transgenes | 2000 |
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
Topics: 5-Methylcytosine; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chromosomes, Human, Pair 3; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HeLa Cells; HT29 Cells; Humans; Lung Neoplasms; Mice; Molecular Sequence Data; Mutation, Missense; Neoplasm Proteins; ral Guanine Nucleotide Exchange Factor; ras Proteins; Rats; RNA-Binding Proteins; Sp1 Transcription Factor; Tumor Suppressor Proteins; Xeroderma Pigmentosum Group A Protein | 2000 |
DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients.
Topics: 5-Methylcytosine; Abnormalities, Multiple; Brain; Cell Line; Centromere; Chromosome Aberrations; Chromosome Fragility; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Cytosine; DNA Methylation; DNA, Satellite; Face; Female; Heterochromatin; Humans; Immunologic Deficiency Syndromes; Infant; Karyotyping; Male; Syndrome; Telomere | 2000 |
DNA bending induced by DNA (cytosine-5) methyltransferases.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Bacterial; DNA, Circular; Escherichia coli; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Restriction Mapping | 2000 |
Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter.
Topics: 5-Methylcytosine; Acetylation; Breast; Breast Neoplasms; Cell Line; Chromatin; CpG Islands; Cytosine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, BRCA1; Histones; Humans; Precipitin Tests; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
RecA protein promotes strand exchange with DNA substrates containing isoguanine and 5-methyl isocytosine.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Replication; DNA-Binding Proteins; DNA, Single-Stranded; Guanine; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Rec A Recombinases; Recombination, Genetic; Substrate Specificity; Thermodynamics | 2000 |
Cytosine deamination plays a primary role in the evolution of mammalian isochores.
Topics: 5-Methylcytosine; Animals; Base Composition; Computer Simulation; CpG Islands; Cytosine; Deamination; DNA; Evolution, Molecular; Humans; Mammals; Mutation; Point Mutation | 2000 |
Atomic model of the 5-methylcytosine-specific restriction enzyme McrA reveals an atypical zinc finger and structural similarity to betabetaalphaMe endonucleases.
Topics: 5-Methylcytosine; Amino Acid Sequence; Cytosine; DNA Restriction Enzymes; Escherichia coli; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Zinc Fingers | 2000 |
Invasion of strongly binding oligonucleotides into tRNA structure.
Topics: 2-Aminopurine; 5-Methylcytosine; Cytosine; Deoxyuridine; Electrophoresis, Polyacrylamide Gel; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; RNA, Transfer, Phe; Time Factors; Yeasts | 2000 |
Bacterial DNA methylation and gene transfer efficiency.
Topics: 5-Methylcytosine; Adenine; Animals; Cell Line; Cells, Cultured; Cytosine; DNA Methylation; DNA Modification Methylases; Escherichia coli; Escherichia coli Proteins; Fibroblasts; Gene Amplification; Gene Deletion; Gene Expression Regulation; Gene Silencing; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Luciferases; Mice; Plasmids; Promoter Regions, Genetic; Rats; Site-Specific DNA-Methyltransferase (Adenine-Specific); Transfection; Transgenes | 2000 |
Sequence-specific and methylation-dependent and -independent binding of rice nuclear proteins to a rice tungro bacilliform virus vascular bundle expression element.
Topics: 5-Methylcytosine; Badnavirus; Base Sequence; CpG Islands; Cytosine; DNA-Binding Proteins; Molecular Sequence Data; Nuclear Proteins; Oryza; Plant Proteins; Plant Shoots; Promoter Regions, Genetic; Protein Binding; Tissue Distribution | 2001 |
DNA of Drosophila melanogaster contains 5-methylcytosine.
Topics: 5-Methylcytosine; Adenosine Triphosphate; Animals; Autoradiography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytosine; DNA; DNA Methylation; Drosophila melanogaster; Phosphotransferases (Phosphate Group Acceptor) | 2000 |
Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.
Topics: 5-Methylcytosine; Biological Assay; Carcinoma, Squamous Cell; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Immunoenzyme Techniques; Isotope Labeling; Lung; Lung Neoplasms; Tritium | 2000 |
Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cell Line; CpG Islands; Cytosine; DNA Methylation; Escherichia coli Proteins; Fibroblasts; Genes, p53; Humans; Lac Operon; Lac Repressors; Mice; Models, Genetic; Molecular Sequence Data; Mutagenesis; Pyrimidine Dimers; Repressor Proteins; Skin Neoplasms; Sunlight; Transcription Factors; Transgenes; Ultraviolet Rays; Viral Proteins | 2001 |
Characterization of carrot nuclear proteins that exhibit specific binding affinity towards conventional and non-conventional DNA methylation.
Topics: 5-Methylcytosine; Binding, Competitive; Cell Differentiation; Cell Division; Cytosine; Daucus carota; DNA Methylation; DNA-Binding Proteins; DNA, Plant; Molecular Weight; Nuclear Proteins; Oligonucleotides; Plant Proteins; Protein Binding | 2000 |
Lowering S-adenosylmethionine levels in Escherichia coli modulates C-to-T transition mutations.
Topics: 5-Methylcytosine; Cytosine; DNA Glycosylases; DNA Methylation; DNA Repair; DNA-Cytosine Methylases; Escherichia coli; Hydrolases; Models, Genetic; Mutagenesis; N-Glycosyl Hydrolases; Point Mutation; S-Adenosylmethionine; Thymine; Uracil-DNA Glycosidase | 2001 |
A link between DNA methylation and epigenetic silencing in transgenic Volvox carteri.
Topics: 5-Methylcytosine; Adenine; Arylsulfatases; Base Sequence; Blotting, Southern; Chlorophyta; Cytosine; DNA; DNA Methylation; Gene Expression Regulation; Gene Silencing; Molecular Sequence Data; Transformation, Genetic | 2001 |
DNA methylation learns to fly.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Drosophila melanogaster; Genes, Insect | 2001 |
Glucocorticoid-induced DNA demethylation and gene memory during development.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Dexamethasone; DNA Methylation; Enhancer Elements, Genetic; Gene Expression Regulation; Gene Silencing; Glucocorticoids; Liver; Rats; Receptors, Glucocorticoid; Transcription Factors; Tumor Cells, Cultured; Tyrosine Transaminase | 2001 |
Genome-wide hypomethylation in hepatocellular carcinogenesis.
Topics: 5-Methylcytosine; Adult; Aged; Carcinoma, Hepatocellular; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA, Neoplasm; Female; Genome, Human; Humans; Isoenzymes; Liver Neoplasms; Long Interspersed Nucleotide Elements; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2001 |
Very-short-patch repair in Escherichia coli requires the dam adenine methylase.
Topics: 5-Methylcytosine; Adenosine Triphosphatases; Bacterial Proteins; Base Pair Mismatch; Blotting, Western; Cytosine; Deamination; DNA Methylation; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Mutation; MutL Proteins; MutS DNA Mismatch-Binding Protein; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 2001 |
The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.
Topics: 5-Methylcytosine; Allosteric Regulation; Allosteric Site; Animals; Catalytic Domain; CpG Islands; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Activation; Kinetics; Mice; Models, Biological; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Zinc | 2001 |
Stability and inheritance of methylation states at PstI sites in Pisum.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chromosome Mapping; Cytosine; DNA Methylation; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Genes, Plant; Genetic Linkage; Genetic Markers; Phylogeny; Pisum sativum; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recombinant Proteins; Saccharomyces cerevisiae | 2001 |
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters.
Topics: 5-Methylcytosine; Amination; Bacteriophage M13; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Cytosine; DNA; DNA Methylation; DNA Primers; DNA, Single-Stranded; DNA, Viral; Genome; Molecular Sequence Data; Nucleic Acid Denaturation; Plasmids; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA; Sulfites; Temperature; Templates, Genetic; Uracil | 2001 |
On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells.
Topics: 5-Methylcytosine; Animals; Arginine; Azacitidine; Cytosine; Dinucleoside Phosphates; DNA Methylation; DNA, Neoplasm; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Mice; Mutagenesis; Tumor Cells, Cultured | 1999 |
Use of DNA molecules substituted with unnatural nucleotides to probe specific drug-DNA interactions.
Topics: 5-Methylcytosine; Base Pairing; Binding Sites; Cytosine; Deoxyribonucleotides; DNA; DNA Primers; DNA Probes; Inosine; Macromolecular Substances; Molecular Structure; Nucleic Acid Conformation; Pharmaceutical Preparations; Polymerase Chain Reaction; Uridine | 2001 |
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Bronchi; Carcinoma, Squamous Cell; Cytosine; Disease Progression; Disease Susceptibility; DNA Methylation; DNA, Neoplasm; Fluorescent Antibody Technique, Indirect; Genetic Predisposition to Disease; Humans; Hyperplasia; Lung Neoplasms; Precancerous Conditions; Respiratory Mucosa; Smoking | 2001 |
Compaction, stainability and methylation of the late replicating X chromosome in mouse female fibroblasts.
Topics: 5-Methylcytosine; Animals; Azure Stains; Bromodeoxyuridine; Chromatin; Cytosine; DNA; DNA Methylation; DNA Replication; Female; Fibroblasts; Indoles; Metaphase; Molecular Conformation; Staining and Labeling; X Chromosome | 2001 |
DNA from Aspergillus flavus contains 5-methylcytosine.
Topics: 5-Methylcytosine; Aspergillus flavus; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytosine; DNA, Fungal; Phosphotransferases (Alcohol Group Acceptor) | 2001 |
Molecular biology. Methylation talk between histones and DNA.
Topics: 5-Methylcytosine; Acetylation; Amino Acid Substitution; Animals; Cytosine; DNA Methylation; DNA, Fungal; Gene Silencing; Histones; Lysine; Methylation; Methyltransferases; Mutation; Neurospora crassa | 2001 |
Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells.
Topics: 5-Methylcytosine; Adenine; Adult; Calcium-Binding Proteins; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cloning, Molecular; CpG Islands; Cytosine; Dinucleotide Repeats; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Fetal Blood; Gene Expression Regulation; Humans; Infant, Newborn; Interferon-gamma; Interleukin-4; Leukocyte Common Antigens; Microfilament Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA; Sulfites; T-Lymphocyte Subsets; Thymine; Tumor Necrosis Factor-alpha | 2002 |
Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context.
Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; Electrophoretic Mobility Shift Assay; Fluorescence; Hot Temperature; Methylation; Molecular Conformation; Oligonucleotides; Stereoisomerism | 2002 |
Measuring DNA demethylase activity in vitro.
Topics: 5-Methylcytosine; Chromatography, Thin Layer; CpG Islands; Cytosine; DNA Methylation; Oligodeoxyribonucleotides; Oxidoreductases, O-Demethylating; Phosphorus Radioisotopes; Plasmids | 2002 |
De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA, Viral; Embryo, Mammalian; Mice; Moloney murine leukemia virus; Mutation; Proviruses; Sequence Analysis, DNA; Stem Cells | 2002 |
Identification and resolution of artifacts in bisulfite sequencing.
Topics: 5-Methylcytosine; Artifacts; Cytosine; DNA Primers; False Positive Reactions; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites | 2002 |
Profiling DNA methylation by melting analysis.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Hot Temperature; Nucleic Acid Denaturation; Polymerase Chain Reaction; Sulfites; Thermodynamics | 2002 |
Analysis of complex methylation data.
Topics: 5-Methylcytosine; Cytosine; Data Interpretation, Statistical; DNA Methylation; Humans | 2002 |
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.
Topics: 5-Methylcytosine; Alleles; Amino Acid Sequence; Animals; Base Pair Mismatch; Cytosine; Deamination; Dinucleoside Phosphates; DNA Methylation; DNA Repair; Endodeoxyribonucleases; Female; Gene Targeting; Genes, APC; Genetic Predisposition to Disease; Intestinal Neoplasms; Intestine, Large; Loss of Heterozygosity; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Point Mutation; Suppression, Genetic | 2002 |
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.
Topics: 5-Methylcytosine; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Breast Neoplasms; Colorectal Neoplasms; CpG Islands; Cystathionine beta-Synthase; Cytosine; DNA Methylation; DNA, Neoplasm; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors | 2002 |
Cellular vitamins, DNA methylation and cancer risk.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Immunohistochemistry; Neoplasms; Risk Factors; Vitamins | 2002 |
Site-specific discrimination of Cytosine and 5-methylcytosine in duplex DNA by Peptide nucleic acids.
Topics: 5-Methylcytosine; Cytosine; DNA; Energy Transfer; Fluorescein; Fluorescence; Genes, p53; Humans; Oligonucleotide Probes; Peptide Nucleic Acids; Substrate Specificity | 2002 |
RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine.
Topics: 5-Methylcytosine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Cysteine; Cytosine; Methyltransferases; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Repressor Proteins; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Transcription Factors; tRNA Methyltransferases | 2002 |
Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chlorocebus aethiops; COS Cells; Cytosine; DNA Damage; DNA Replication; Genetic Vectors; Mutagenesis, Site-Directed; Mutagens; Mutation; Oligodeoxyribonucleotides; Oxidation-Reduction; Plasmids; Templates, Genetic; Transfection | 2002 |
Specific methylation of the CpG-rich domains in the promoter of the human tissue transglutaminase gene.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; CpG Islands; Cytosine; DNA; DNA Methylation; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transglutaminases | 2002 |
5-Methylcytosine as a marker for the monitoring of DNA methylation.
Topics: 5-Methylcytosine; Biomarkers; Chromatography; Cytosine; DNA Methylation; Electrophoresis; Mass Spectrometry | 2002 |
Parental 5-methylcytosine methylation patterns are stable upon inter-species hybridization of Xiphophorus (Teleostei: Poeciliidae) fish.
Topics: 5-Methylcytosine; Animals; Blotting, Southern; Chromosome Mapping; Crosses, Genetic; Cyprinodontiformes; Cytosine; DNA; DNA Methylation; DNA Probes; DNA Restriction Enzymes; Exons; Female; Gene Expression Regulation; Genomic Imprinting; Introns; Male; Phenotype; Species Specificity | 2002 |
Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development.
Topics: 5-Methylcytosine; Animals; Blotting, Southern; Cytosine; DNA; DNA Methylation; DNA Probes; Embryonic and Fetal Development; Female; Genome; Genomic Imprinting; Male; Morphogenesis; Oryzias; Pregnancy; Restriction Mapping; Species Specificity | 2002 |
Distribution of 5-methylcytosine residues in 5S rRNA genes in Arabidopsis thaliana and Secale cereale.
Topics: 5-Methylcytosine; Arabidopsis; Base Sequence; Blotting, Southern; Cytosine; DNA Methylation; DNA Primers; DNA, Plant; Genes, Plant; Molecular Sequence Data; Nicotiana; Polymerase Chain Reaction; RNA, Ribosomal, 5S; Secale | 2002 |
Methylation of a euchromatin-heterochromatin transition region in Arabidopsis thaliana chromosome 5 left arm.
Topics: 5-Methylcytosine; Arabidopsis; Blotting, Southern; Chromosomes; Chromosomes, Artificial, Yeast; CpG Islands; Cytosine; DNA Methylation; DNA, Plant; DNA, Ribosomal; Euchromatin; Gene Expression Regulation, Plant; Genome, Plant; Heterochromatin; In Situ Hybridization, Fluorescence; Mutation; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Saccharomyces cerevisiae | 2002 |
The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deamination; Deoxyribonuclease (Pyrimidine Dimer); DNA Primers; Endodeoxyribonucleases; Humans | 2003 |
Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Carcinogens, Environmental; Cell Cycle; Comet Assay; Cytosine; Deoxyguanosine; DNA; Fibroblasts; Flow Cytometry; Fumonisins; Glioma; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Knockout; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis.
Topics: 5-Methylcytosine; Base Sequence; Cell Line; CpG Islands; Cytosine; Deamination; DNA Methylation; Humans; Molecular Sequence Data; Mutagenesis; Pyrimidine Dimers; Ultraviolet Rays | 2003 |
[Capillary gas chromatographic analysis and mass spectrometric identification of modified DNA bases 5-methylcytosine and 8-hydroxyguanine].
Topics: 5-Methylcytosine; Chromatography, Gas; Cytosine; DNA; DNA Methylation; Guanine; Humans; Mass Spectrometry; Reproducibility of Results | 2000 |
Transient decreases in methylation at 5'-cCGG-3' sequences in potato (Solanum tuberosum L.) meristem DNA during progression of tubers through dormancy precede the resumption of sprout growth.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Cytosine; DNA Methylation; DNA, Plant; Genome, Plant; Meristem; Polymorphism, Restriction Fragment Length; Solanum tuberosum; Time Factors | 2003 |
Genome-wide epigenetic alterations in cloned bovine fetuses.
Topics: 5-Methylcytosine; Animals; Cattle; Cloning, Organism; Cytosine; DNA Methylation; Female; Fetal Viability; Fetus; Pregnancy | 2003 |
A systematic profile of DNA methylation in human cancer cell lines.
Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured | 2003 |
Sequence context at human single nucleotide polymorphisms: overrepresentation of CpG dinucleotide at polymorphic sites and suppression of variation in CpG islands.
Topics: 5-Methylcytosine; Alleles; Chromosomes; CpG Islands; Cytosine; Databases, Factual; Deamination; Dinucleotide Repeats; DNA Methylation; DNA Primers; Gene Frequency; Genetic Variation; Genome, Human; Humans; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2003 |
The epsilon-sarcoglycan gene (SGCE), mutated in myoclonus-dystonia syndrome, is maternally imprinted.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; Cytoskeletal Proteins; Dystonic Disorders; Female; Genomic Imprinting; Humans; Male; Membrane Glycoproteins; Myoclonus; Pedigree; Sarcoglycans; Sequence Analysis, DNA | 2003 |
Modulation of human nucleotide excision repair by 5-methylcytosines.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA Repair; Genetic Vectors; Humans; Simian virus 40 | 2003 |
Cytosine methylation by the SuaI restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon.
Topics: 5-Methylcytosine; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; Mutation; Substrate Specificity; Sulfolobus acidocaldarius | 2003 |
EPR and ENDOR study of crystalline cytosine x HCl doped with 5-methylcytosine. Radiation-induced radical formation and hole transfer.
Topics: 5-Methylcytosine; Crystallization; Cytosine; Electron Spin Resonance Spectroscopy; Electrons; Free Radicals; Hydrochloric Acid; Magnetic Resonance Spectroscopy; Magnetics; Models, Chemical; Protons; Radiation, Ionizing; Temperature | 2003 |
Nucleic acid economy in bacteria infected with bacteriophage T2. I. Purine and pyrimidine composition.
Topics: 5-Methylcytosine; Bacteria; Bacteriophage T4; Bacteriophages; Cytosine; Escherichia coli; Nucleic Acids; Purines | 1953 |
The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Bacteriophages; Cytosine; Nucleic Acids; Pyrimidines; Viruses | 1953 |
Some precursors of the 5-hydroxymethylcytosine of T6r+ bacteriophage.
Topics: 5-Methylcytosine; Bacteriophages; Cytosine; Pyrimidines | 1954 |
[RADIOAUTOGRAPHIC STUDY OF H3-5-METHYLCYTOSINE INCORPORATION IN ACETABULARIA MEDITERRANEA].
Topics: 5-Methylcytosine; Acetabularia; Autoradiography; Cytosine; Eukaryota; Proteins; Research; RNA; Tritium | 1963 |
Recognition and estimation of 5-methylcytosine in nucleic acids.
Topics: 5-Methylcytosine; Cytosine; Nucleic Acids | 1951 |
Tissue-specific elevated genomic cytosine methylation levels are associated with an overgrowth phenotype of bovine fetuses derived by in vitro techniques.
Topics: 5-Methylcytosine; Animals; Cattle; Cytosine; DNA; Extraembryonic Membranes; Female; Fertilization in Vitro; Fetal Development; Fetus; Genome; Insemination, Artificial; Liver; Methylation; Nuclear Transfer Techniques; Phenotype | 2004 |
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic | 2004 |
Cytosine methylation and CpG, TpG (CpA) and TpA frequencies.
Topics: 5-Methylcytosine; Animals; Anopheles; Base Composition; CpG Islands; Cytosine; DNA; DNA Methylation; Drosophila melanogaster; GC Rich Sequence; Genome; Genome Components; Humans; Tetraodontiformes; Zebrafish | 2004 |
Structural evidence of a passive base-flipping mechanism for beta-glucosyltransferase.
Topics: 5-Methylcytosine; Adenine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cytosine; DNA; Glucosyltransferases; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Protein Binding; Protein Conformation; Uridine Diphosphate | 2004 |
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Chromosomal Proteins, Non-Histone; CpG Islands; Cytosine; DNA Damage; DNA Methylation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Guanosine; Methyl-CpG-Binding Protein 2; Models, Molecular; Oligodeoxyribonucleotides; Oxidative Stress; Protein Structure, Tertiary; Repressor Proteins | 2004 |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Cell Line; Codon, Initiator; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Hematopoietic System; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; K562 Cells; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; NIH 3T3 Cells; Promoter Regions, Genetic; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Transcription Initiation Site; Transfection | 2004 |
Determination of 5-methyl-cytosine and cytosine in tumor DNA of cancer patients.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Capillary; Humans; Neoplasms; Reproducibility of Results | 2005 |
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.
Topics: 5-Methylcytosine; Acetylation; Azacitidine; Chromatin Assembly and Disassembly; Cytosine; DNA Methylation; Epigenesis, Genetic; Histones; Hydroxamic Acids; Solanum tuberosum; Transcription, Genetic | 2005 |
Direct detection of methylation in genomic DNA.
Topics: 5-Methylcytosine; Adenine; Cytosine; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA Methylation; DNA, Bacterial; Genome, Bacterial; Genomics | 2005 |
DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.
Topics: 5-Methylcytosine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cytosine; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Sequence Alignment; Thymine; Trans-Activators | 2006 |
Sequence-selective osmium oxidation of DNA: efficient distinction between 5-methylcytosine and cytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Kinetics; Methods; Nucleic Acid Conformation; Nucleic Acid Hybridization; Osmium; Oxidation-Reduction | 2006 |
Sequence-selective 5-methylcytosine oxidation for epigenotyping.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Methylation; Genotype; Hydroxylation; Nucleic Acid Hybridization; Osmium Tetroxide; Oxidation-Reduction | 2005 |
Does urea promote the bisulfite-mediated deamination of cytosine in DNA? Investigation aiming at speeding-up the procedure for DNA methylation analysis.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cytosine; Deamination; DNA; DNA Methylation; Humans; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Urea | 2006 |
Fluorescence quenching by methylcytosine-metal complexation.
Topics: 2-Naphthylamine; 5-Methylcytosine; Base Pairing; Cytosine; DNA Probes; Fluorescent Dyes; Osmium | 2006 |
Sensitive discrimination between cytosine and 5-methylcytosine in DNA by a modified invader method.
Topics: 5-Methylcytosine; Cytosine; DNA; Flap Endonucleases; Fluorescent Dyes; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Oligonucleotide Probes; Photochemistry; Spectrometry, Fluorescence | 2006 |
A type IV modification dependent restriction nuclease that targets glucosylated hydroxymethyl cytosine modified DNAs.
Topics: 5-Methylcytosine; Capsid Proteins; Chromatography, Affinity; Coliphages; Cytosine; DNA Restriction Enzymes; DNA, Viral; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Mutant Proteins; Myoviridae; Nucleic Acid Conformation; Nucleotides; Protein Binding; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity | 2007 |
Exclusion of glucosyl-hydroxymethylcytosine DNA containing bacteriophages is overcome by the injected protein inhibitor IPI*.
Topics: 5-Methylcytosine; Amino Acid Sequence; Bacteriophage T4; Bacteriophages; Base Sequence; Capsid Proteins; Clone Cells; Cytosine; DNA Restriction Enzymes; DNA, Viral; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Molecular Sequence Data; Prophages; Sequence Analysis, DNA; Substrate Specificity | 2007 |
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; Substrate Specificity | 2007 |
Direct labeling of 5-methylcytosine and its applications.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Electrochemistry; Electrodes; Genes, p53; Gold; Indicators and Reagents; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutation; Oligonucleotides; Osmium Compounds; Oxidation-Reduction; Pyridines; Spectrometry, Fluorescence | 2007 |
Chemistry of bisulfite genomic sequencing; advances and issues.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cytosine; Deamination; DNA Methylation; Genomics; Humans; Quaternary Ammonium Compounds; Sequence Analysis, DNA; Sulfites; Urea | 2007 |
A new synthesis of cytosine and 5-methylcytosine.
Topics: 5-Methylcytosine; Cytosine | 1949 |
Photocurrent response after enzymatic treatment of DNA duplexes immobilized on gold electrodes: electrochemical discrimination of 5-methylcytosine modification in DNA.
Topics: 5-Methylcytosine; Anthraquinones; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Methylation; Electrochemistry; Electrodes; Electroretinography; Gold; Molecular Conformation; Oligodeoxyribonucleotides; Photochemistry; Photosensitizing Agents; Time Factors | 2008 |
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning.
Topics: 5-Methylcytosine; Animals; Arabidopsis; Base Sequence; Computational Biology; Cytosine; DNA Methylation; Gene Expression Regulation, Plant; Gene Library; Genome, Plant; Mice; Mutation; Promoter Regions, Genetic; Reproducibility of Results; Sequence Analysis, DNA; Sulfites; Uracil | 2008 |
The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Adenoma; Adult; Aged; Aged, 80 and over; Carcinoma; Colonic Neoplasms; Cytosine; Deoxyguanosine; DNA Damage; Female; Humans; Leukocytes; Male; Middle Aged | 2008 |
The mildiomycin biosynthesis: initial steps for sequential generation of 5-hydroxymethylcytidine 5'-monophosphate and 5-hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119.
Topics: 5-Methylcytosine; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Cytidine Monophosphate; Cytosine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Multigene Family; Sequence Alignment; Streptomycetaceae; Substrate Specificity | 2008 |
Genome-scale relationships between cytosine methylation and dinucleotide abundances in animals.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; Dinucleotide Repeats; DNA Methylation; Genome; Humans; Mice; Mutation; Sequence Analysis, DNA | 2008 |
Endogenous cytosine methylation and the formation of carcinogen carcinogen-DNA adducts.
Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pairing; Carcinogens; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Stereoisomerism | 2008 |
The reaction of cytosine with bisulfite by base flipping from the duplex.
Topics: 5-Methylcytosine; Base Pair Mismatch; Carbamates; Chromatography, High Pressure Liquid; Cytosine; DNA; Hydroxylamine; Naphthyridines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfites | 2008 |
Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA, Single-Stranded; Nucleic Acid Conformation; Oligonucleotides; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Temperature | 2008 |
RNA cytosine methylation analysis by bisulfite sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; Drosophila melanogaster; Methylation; RNA; RNA, Ribosomal, 16S; RNA, Transfer, Asp; Sequence Analysis, RNA; Sulfites | 2009 |
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Cell Line; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Hydroxylation; Mass Spectrometry; Mice; Mixed Function Oxygenases; Molecular Sequence Data; Proto-Oncogene Proteins; RNA Interference; Sequence Alignment; Transfection | 2009 |
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cell Line; Cerebellum; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytosine; Deoxycytidine; DNA; DNA Damage; Humans; Mass Spectrometry; Mice; Purkinje Cells | 2009 |
The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analytic Sample Preparation Methods; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Codon; Cytosine; DNA; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Humans; Microchemistry; Mutagens; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.
Topics: 5-Methylcytosine; Animals; Apoptosis; Azacitidine; Blastocyst; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytosine; Decitabine; DNA Fragmentation; DNA Methylation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids | 2009 |
Photoelectrochemical identification of 5-methylcytosine modification in DNA: combination of photosensitization and enzymatic cleavage.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA Restriction Enzymes; Oligodeoxyribonucleotides; Photochemical Processes; Photochemistry | 2009 |
The genome of the stick insect Medauroidea extradentata is strongly methylated within genes and repetitive DNA.
Topics: 5-Methylcytosine; Animals; Bees; CpG Islands; Cytosine; DNA Methylation; DNA Restriction Enzymes; Drosophila melanogaster; Gene Silencing; Genetic Techniques; Genome; Genomics; Insecta; Repetitive Sequences, Nucleic Acid; Transcription, Genetic | 2009 |
Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Damage; Electrons; Humans; Hydroxyl Radical; Mice; Mutation; Oxidants; Oxidation-Reduction; Water | 2010 |
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.
Topics: 5-Methylcytosine; Base Sequence; Chromatography, Liquid; Cytosine; Mass Spectrometry; Molecular Sequence Data; Polymerase Chain Reaction; Sulfites | 2010 |
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Antibodies; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Immunoprecipitation; Oligonucleotides; Sequence Analysis, DNA; Sulfites | 2010 |
Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA; DNA Methylation; DNA Restriction Enzymes; Genes, BRCA1; Humans; Octamer Transcription Factor-3; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites | 2010 |
Direct electrochemical detection of DNA methylation for retinoblastoma and CpG fragments using a nanocarbon film.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA Methylation; Electrochemical Techniques; Electrodes; Genes, Retinoblastoma; Hydrogen-Ion Concentration; Nanotubes, Carbon; Oxidation-Reduction | 2010 |
Quantification of the sixth DNA base hydroxymethylcytosine in the brain.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cytosine; DNA; DNA Methylation; Mice | 2010 |
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Topics: 5-Methylcytosine; Alkaline Phosphatase; Animals; Blastocyst Inner Cell Mass; Cell Proliferation; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Homeodomain Proteins; Mice; Nanog Homeobox Protein; Proto-Oncogene Proteins | 2010 |
Mutual relationship between stacking and hydrogen bonding in DNA. Theoretical study of guanine-cytosine, guanine-5-methylcytosine, and their dimers.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; Dimerization; DNA; Guanine; Hydrogen Bonding; Models, Molecular; Quantum Theory; Thermodynamics | 2010 |
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; DNA; Embryonic Stem Cells; Genetic Techniques; Genome; Glucosyltransferases; Mice | 2010 |
Bisulphite sequencing of plant genomic DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Methylation; DNA, Plant; DNA, Single-Stranded; Epigenomics; Genome, Plant; Plants; Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Uracil | 2010 |
Chemical discrimination between dC and 5MedC via their hydroxylamine adducts.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; DNA; DNA Adducts; DNA Methylation; Hydroxylamines; Isomerism; Models, Molecular; Oligodeoxyribonucleotides; Sequence Analysis, DNA | 2010 |
Identification of epigenetic DNA modifications with a protein nanopore.
Topics: 5-Methylcytosine; Cyclodextrins; Cytosine; DNA; Epigenesis, Genetic; Hemolysin Proteins; Nanopores | 2010 |
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation.
Topics: 5-Methylcytosine; Alleles; Animals; Chromosome Duplication; CpG Islands; Cytosine; DNA Methylation; Genomic Imprinting; Kidney; Liver; Mice; Sensitivity and Specificity; Sequence Analysis, DNA | 2011 |
Pyrimidine-pyrimidine base pairs stabilized by silver(I) ions.
Topics: 5-Methylcytosine; Base Pair Mismatch; Base Pairing; Cytosine; Hydrogen Bonding; Ions; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pyrimidines; Silver; Thymine | 2011 |
Efficient synthesis of 5-hydroxymethylcytosine containing DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Genome; Molecular Structure | 2010 |
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Bacteriophage T4; Biotin; Cerebellum; Cytosine; DNA; Genome; Genome, Human; Glucosyltransferases; HEK293 Cells; HeLa Cells; Humans; Mice; Models, Molecular; Molecular Sequence Data; Sequence Analysis, DNA; Staining and Labeling | 2011 |
Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecules.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Molecular Dynamics Simulation; Nucleic Acid Conformation; Polymerase Chain Reaction | 2011 |
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
Topics: 5-Methylcytosine; Animals; Calibration; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytosine; DNA Methylation; Immunohistochemistry; Mass Spectrometry; Mice; Models, Chemical; Oxygen; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution | 2010 |
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Topics: 5-Methylcytosine; Amino Acid Substitution; Animals; Binding, Competitive; Biocatalysis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catalytic Domain; Cell Line, Tumor; Cytosine; Dioxygenases; DNA-Binding Proteins; Endostatins; F-Box Proteins; Gene Expression; Glioma; Glutarates; Histone Demethylases; Histones; Homeodomain Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isocitrate Dehydrogenase; Jumonji Domain-Containing Histone Demethylases; Ketoglutaric Acids; Mixed Function Oxygenases; Models, Molecular; Oxalates; Oxidoreductases, N-Demethylating; Procollagen-Proline Dioxygenase; Proto-Oncogene Proteins | 2011 |
A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples.
Topics: 5-Methylcytosine; Animals; Catalytic Domain; Chromatography, Liquid; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Fibroblasts; Humans; Hydroxylation; Induced Pluripotent Stem Cells; Mass Spectrometry; Mice; Mixed Function Oxygenases; Proto-Oncogene Proteins; Reproducibility of Results | 2011 |
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Binding Sites; Cell Differentiation; Cell Lineage; Chromatin Immunoprecipitation; Computational Biology; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; Mice; Octamer Transcription Factor-3; Proto-Oncogene Proteins; Teratoma | 2011 |
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Topics: 5-Methylcytosine; Carrier Proteins; Cytosine; DNA; Embryonic Stem Cells; Gene Expression Regulation; Genome, Human; Genomics; Glucosyltransferases; Humans; Promoter Regions, Genetic; Protozoan Proteins | 2011 |
High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cytosine; DNA; DNA Methylation; Mice; Mice, Inbred BALB C; Polymerase Chain Reaction | 2011 |
DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Base Sequence; Cell Compartmentation; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Mitochondrial; Genes, Mitochondrial; HCT116 Cells; Humans; Mice; Mitochondria; Molecular Sequence Data; Oxidative Stress; Protein Binding; Protein Sorting Signals; Transcription, Genetic | 2011 |
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.
Topics: 5-Methylcytosine; Animals; Cellular Reprogramming; Chromosomal Proteins, Non-Histone; Cleavage Stage, Ovum; Cytosine; DNA-Binding Proteins; Embryo, Mammalian; Female; Fertilization; Gene Expression Regulation, Developmental; Genome; Male; Mice; Oocytes; Oxidation-Reduction; Repressor Proteins; Sequence Analysis, DNA; Sulfites; Zygote | 2011 |
Methyltransferase-directed derivatization of 5-hydroxymethylcytosine in DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; S-Adenosylmethionine; Selenium Compounds; Sulfhydryl Compounds | 2011 |
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Cleavage; DNA Restriction Enzymes; Genome; Mice | 2011 |
Genomic mapping of 5-hydroxymethylcytosine in the human brain.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cytosine; DNA; Gene Expression; Genomics; Humans; Mice; Promoter Regions, Genetic | 2011 |
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.
Topics: 5-Methylcytosine; Animals; Cattle; Cell Nucleus; Chromosomal Proteins, Non-Histone; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryo, Mammalian; Epigenomics; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Mammals; Mice; Mice, Knockout; Nuclear Transfer Techniques; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Repressor Proteins; Sex Factors; Zygote | 2011 |
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Silencing; Genome; Mice; Polycomb-Group Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Repressor Proteins; Transcription, Genetic | 2011 |
Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; Cytosine Nucleotides; Dinucleoside Phosphates; DNA; DNA Methylation; Humans; Hydroxylation; Methylation; Molecular Sequence Data; Molecular Structure; Polymerase Chain Reaction | 2011 |
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatin; Cytosine; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genome-Wide Association Study; Mice; Proto-Oncogene Proteins; Transcription Factors | 2011 |
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Topics: 5-Methylcytosine; Animals; Antibodies; Cell Differentiation; Cell Line; Cell Lineage; CpG Islands; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Embryoid Bodies; Embryonic Stem Cells; Euchromatin; Exons; Gene Expression Regulation, Developmental; Gene Silencing; Genome; Mice; Pluripotent Stem Cells; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reproducibility of Results; Sequence Analysis, DNA; Transcription, Genetic | 2011 |
Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; Organophosphorus Compounds; Siloxanes; Styrenes | 2011 |
Enzymatic labeling of 5-hydroxymethylcytosine in DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Glycosyltransferases; Humans; Isotope Labeling; Tritium | 2011 |
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Topics: 5-Methylcytosine; Animals; Cell Line; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Embryonic Stem Cells; Gene Knockdown Techniques; Mice; Protein Binding; Proto-Oncogene Proteins; Repressor Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Transcription Initiation Site; Transcription, Genetic | 2011 |
Facile synthesis of hydroxymethylcytosine-containing oligonucleotides and their reactivity upon osmium oxidation.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; Models, Molecular; Molecular Structure; Oligonucleotides; Osmium; Oxidation-Reduction; Stereoisomerism; Transition Temperature | 2011 |
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Genome-Wide Association Study; Mice; Mixed Function Oxygenases; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins | 2011 |
Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(α)I.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA-Directed RNA Polymerases; Glycosylation | 2011 |
Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
Topics: 5-Methylcytosine; Animals; Azides; Biotin; Cell Line; Click Chemistry; Cross-Linking Reagents; Cytosine; Diazomethane; DNA; DNA Probes; Genome; Glucosyltransferases; Humans; Mice; Streptavidin; Ultraviolet Rays | 2011 |
A sustained dietary change increases epigenetic variation in isogenic mice.
Topics: 5-Methylcytosine; Alleles; Animals; CpG Islands; Cytosine; Dietary Supplements; DNA Methylation; Environment; Epigenesis, Genetic; Gene Expression; Genetic Loci; Genetic Variation; Mice; Mice, Inbred C57BL; Phenotype; Principal Component Analysis; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Stochastic Processes; Sulfites | 2011 |
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Biotinylation; Cell Line; Cytosine; DNA Methylation; Embryonic Stem Cells; Exons; Gene Expression Regulation, Developmental; Genome; Glucose; Mice; Periodic Acid; Promoter Regions, Genetic; Sequence Analysis, DNA; Transcription Initiation Site; Transcription, Genetic | 2011 |
Epigenetics: Tet proteins in the limelight.
Topics: 5-Methylcytosine; Animals; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Genome; Mice; Polycomb-Group Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Repressor Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Transcription, Genetic | 2011 |
Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes.
Topics: 5-Methylcytosine; Animals; Brain; CpG Islands; Cytosine; DNA Methylation; Embryonic Stem Cells; Genome, Human; HeLa Cells; Humans; Mice; Myocardium; NIH 3T3 Cells; Organ Specificity | 2011 |
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA-Binding Proteins; Gene Expression Profiling; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Mutation; Proto-Oncogene Proteins | 2011 |
Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.
Topics: 5-Methylcytosine; Cytosine; Deoxycytidine; DNA; Methylation; Molecular Structure; Oligonucleotides; Oxidation-Reduction | 2011 |
Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage β-glucosyltransferase.
Topics: 5-Methylcytosine; Bacteriophage T4; Cytosine; DNA; Glucose; Glucosyltransferases; Humans | 2011 |
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.
Topics: 5-Methylcytosine; Base Composition; Binding Sites; Cytosine; Embryonic Stem Cells; Enhancer Elements, Genetic; Gene Expression Regulation, Developmental; Humans; Transcription Factors | 2011 |
Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine by a chemically designed peptide.
Topics: 5-Methylcytosine; Cytosine; DNA; Electrophoretic Mobility Shift Assay; Oxidation-Reduction; Phosphopeptides; Phosphotyrosine; Protein Kinases; Zinc Fingers | 2011 |
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression.
Topics: 5-Methylcytosine; Cytosine; Gene Expression Regulation; HeLa Cells; Humans; Promoter Regions, Genetic; Repressor Proteins; RNA Polymerase II; Transcription, Genetic | 2011 |
The discovery of 5-formylcytosine in embryonic stem cell DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Embryonic Stem Cells; Mass Spectrometry; Mice | 2011 |
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.
Topics: 5-Methylcytosine; Animals; Cell Cycle Proteins; Cytidine Deaminase; Cytosine; DNA Methylation; Embryonic Development; Female; Gene Expression Regulation, Developmental; Gene Knock-In Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Proteins; Promoter Regions, Genetic; Thymine DNA Glycosylase; Transcription, Genetic | 2011 |
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells.
Topics: 5-Methylcytosine; Binding Sites; Cell Line; Chromosome Mapping; Cytosine; DNA Methylation; Embryonic Stem Cells; Epigenomics; Gene Expression Regulation; Gene Library; Genome, Human; Heterochromatin; Histones; Humans; Immunoblotting; Metaphase; Promoter Regions, Genetic; Sequence Alignment; Transcription Factors | 2011 |
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
Topics: 5-Methylcytosine; Binding Sites; CCAAT-Enhancer-Binding Proteins; CpG Islands; Cytosine; DNA; HEK293 Cells; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Thermodynamics | 2011 |
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Lineage; Colony-Forming Units Assay; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Erythropoiesis; Fetal Blood; Genetic Vectors; Granulocytes; Hematopoietic Stem Cells; Humans; Lentivirus; Monocytes; Mutation; Myelopoiesis; Proto-Oncogene Proteins; RNA Interference; RNA, Small Interfering | 2011 |
Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.
Topics: 5-Methylcytosine; Animals; Antibodies; Bone Marrow; Cell Differentiation; Cell Lineage; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; Embryonic Development; Embryonic Stem Cells; Genome, Human; Humans; Induced Pluripotent Stem Cells; Intermediate Filament Proteins; Mice; Nerve Tissue Proteins; Nestin; Neurons; Zygote | 2011 |
2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).
Topics: 5-Methylcytosine; Adenine; Biological Products; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Cytosine; DNA; Guanine; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA; Thymine | 2011 |
Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Profiling; Genome; Mice; Proto-Oncogene Proteins; Transcription, Genetic | 2011 |
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Recombinant Fusion Proteins | 2011 |
Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Chromosome Mapping; Conserved Sequence; Cytosine; DNA Cleavage; DNA Restriction Enzymes; Genomics; Molecular Sequence Data; Rats; Substrate Specificity | 2011 |
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Topics: 5-Methylcytosine; Animals; Animals, Newborn; Body Size; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Embryonic Stem Cells; Female; Fertility; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Genetic Complementation Test; Mice; Mice, Inbred C57BL; Pluripotent Stem Cells; Proto-Oncogene Proteins; Tetraploidy | 2011 |
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; RNA, Small Interfering; Thymine DNA Glycosylase; Transfection | 2011 |
Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Gene Expression Profiling; Gene Expression Regulation; Genes, Tumor Suppressor; Genome; Mice; Mice, Knockout; NF-kappa B; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2011 |
Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.
Topics: 5-Methylcytosine; Cytosine; DNA; Histone Demethylases; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Structure-Activity Relationship | 2011 |
Molecular biology. Demystifying DNA demethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Thymine DNA Glycosylase | 2011 |
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
Topics: 5-Methylcytosine; Alleles; Animals; Cellular Reprogramming; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Epigenesis, Genetic; Female; Fertility; Gene Expression Regulation, Developmental; Germ Cells; Male; Mice; Octamer Transcription Factor-3; Oocytes; Oxidation-Reduction; Proto-Oncogene Proteins; Zygote | 2011 |
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
Topics: 5-Methylcytosine; Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Differentiation; Colonic Neoplasms; Cytosine; Down-Regulation; Embryo, Mammalian; Female; Gestational Age; HEK293 Cells; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Prostatic Neoplasms; Stem Cells | 2011 |
Selective derivatization of cytosine and methylcytosine moieties with 2-bromoacetophenone for submicrogram DNA methylation analysis by reversed phase HPLC with spectrofluorimetric detection.
Topics: 5-Methylcytosine; Acetophenones; Animals; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cytidine; Cytosine; Deoxycytidine; DNA Methylation; Fluorometry; Humans; Lepidium sativum; Oligochaeta; Salmon | 2011 |
Electrochemical DNA methylation detection for enzymatically digested CpG oligonucleotides.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Electrochemical Techniques; Fungal Proteins; Nanotubes, Carbon; Oligodeoxyribonucleotides; Oxidation-Reduction; Single-Strand Specific DNA and RNA Endonucleases | 2011 |
5-Hydroxymethylcytosine-selective oxidation with peroxotungstate.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA, Single-Stranded; Oxidation-Reduction; Substrate Specificity; Tungsten Compounds | 2011 |
Promoter methylation and age-related downregulation of Klotho in rhesus monkey.
Topics: 5-Methylcytosine; Aging; Animals; Brain; Cell Line; Cytosine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation; Glucuronidase; Klotho Proteins; Macaca mulatta; Male; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors | 2012 |
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos.
Topics: 5-Methylcytosine; Animals; Blastocyst; Chromatids; Chromosomes, Mammalian; Cytosine; Dioxygenases; DNA Replication; DNA-Binding Proteins; Embryonic Development; Mice; Mitosis; Proto-Oncogene Proteins; Sister Chromatid Exchange; Zygote | 2011 |
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Topics: 5-Methylcytosine; Aging; Analysis of Variance; Animals; Animals, Newborn; Cerebellum; Chromosome Deletion; Chromosome Mapping; Cytosine; Disease Models, Animal; DNA Methylation; Epigenomics; Gene Expression Regulation, Developmental; Hippocampus; Humans; Immunoprecipitation; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Organ Specificity; Phosphopyruvate Hydratase; Rett Syndrome; X Chromosome | 2011 |
Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis.
Topics: 5-Methylcytosine; Adult; Antigens, Differentiation; Brain-Derived Neurotrophic Factor; Case-Control Studies; Cytosine; DNA Methylation; Female; Gene Expression; Humans; Male; Middle Aged; Parietal Lobe; Prefrontal Cortex; Promoter Regions, Genetic; Psychotic Disorders | 2012 |
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Lung Neoplasms; Male; Mice; Mixed Function Oxygenases; Molecular Structure; Mutation; Neoplasms; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Improved synthesis and mutagenicity of oligonucleotides containing 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; Molecular Structure; Mutagens; Oligonucleotides; Organophosphorus Compounds; Spectrometry, Mass, Electrospray Ionization | 2011 |
Epigenetic regulation of motor neuron cell death through DNA methylation.
Topics: 5-Methylcytosine; Age Factors; Amyloid Precursor Protein Secretases; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Aspartic Acid Endopeptidases; Camptothecin; Caspase 3; Cell Line, Transformed; Central Nervous System; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Enzyme Inhibitors; Epigenomics; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Humans; Indoles; Mice; Mice, Transgenic; Motor Neurons; Mutation; Phthalimides; Propionates; RNA, Small Interfering; Sciatic Neuropathy; Superoxide Dismutase; Transfection; Tryptophan; Up-Regulation | 2011 |
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; Sensitivity and Specificity; Sequence Analysis, DNA | 2011 |
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.
Topics: 5-Methylcytosine; Animals; Cell Line; Cells, Cultured; Chromosome Mapping; Cluster Analysis; Cytosine; DNA; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Genetic Loci; Humans; Mice; Nuclear Proteins; Organ Specificity; Promoter Regions, Genetic; RNA-Binding Proteins; Transcription, Genetic | 2012 |
Methylation on the mind.
Topics: 5-Methylcytosine; Aging; Animals; Cerebellum; Cytosine; Epigenomics; Gene Expression Regulation, Developmental; Hippocampus; Humans | 2011 |
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.
Topics: 5-Methylcytosine; Animals; Antibodies; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Embryonic Development; Immunohistochemistry; Male; Mice | 2011 |
The hunt for 5-hydroxymethylcytosine: the sixth base.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; Epigenesis, Genetic; Sequence Analysis, DNA | 2011 |
5-Hydroxymethylcytosine: a new kid on the epigenetic block?
Topics: 5-Methylcytosine; Animals; Cell Line; Chromatin; Cluster Analysis; Cytosine; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mice; Oxygenases; Transcription, Genetic; Translocation, Genetic | 2011 |
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Chromatin Assembly and Disassembly; Cytosine; DNA Helicases; DNA-Binding Proteins; Embryonic Stem Cells; Gene Knockdown Techniques; Humans; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mice; Nuclear Proteins; Proto-Oncogene Proteins; RNA Polymerase II; Transcription Factors | 2011 |
Quantitative measurement of genome-wide DNA methylation by a reliable and cost-efficient enzyme-linked immunosorbent assay technique.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cost-Benefit Analysis; Cytosine; DNA; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genome, Human; Humans; Keratinocytes; Spectrometry, Mass, Electrospray Ionization | 2012 |
Tracking genomic hydroxymethylation by the base.
Topics: 5-Methylcytosine; Cytosine; DNA; Sequence Analysis, DNA | 2011 |
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation; Homeodomain Proteins; Leukemia Inhibitory Factor; MAP Kinase Signaling System; Mice; Nanog Homeobox Protein; Proto-Oncogene Proteins; RNA Interference; Signal Transduction; STAT3 Transcription Factor | 2012 |
Biochemical characterization of recombinant β-glucosyltransferase and analysis of global 5-hydroxymethylcytosine in unique genomes.
Topics: 5-Methylcytosine; Animals; Arabidopsis Proteins; Bacteriophage T4; Cattle; Cytosine; Deoxyribonucleases, Type II Site-Specific; Escherichia coli; Escherichia coli Proteins; Female; Genome, Plant; Genome, Viral; Glucosyltransferases; HCT116 Cells; HEK293 Cells; Humans; Male; Mice; NIH 3T3 Cells; Rats; Recombinant Proteins; Substrate Specificity | 2012 |
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Anaplasia; Astrocytoma; Brain; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Cytosine; DNA; Epigenesis, Genetic; Female; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation; Young Adult | 2012 |
The involvement of 5-hydroxymethylcytosine in active DNA demethylation in mice.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cytosine; DNA; DNA Methylation; Embryo, Mammalian; Gene Expression Regulation, Developmental; Metaphase; Mice; Oocytes; Plasmids | 2012 |
Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction.
Topics: 5-Methylcytosine; Age Factors; Animals; Caloric Restriction; Cytosine; DNA Methyltransferase 3A; Gene Expression Regulation; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Superoxide Dismutase; Superoxide Dismutase-1; Tissue Distribution | 2012 |
The role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Humans; Translocation, Genetic | 2012 |
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Glucosyltransferases; Magnetic Phenomena; Microspheres | 2012 |
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA-Binding Proteins; Gene Knockdown Techniques; Humans; Mixed Function Oxygenases; Mutation; Neoplasms; Proto-Oncogene Proteins; Stomach Neoplasms | 2012 |
TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.
Topics: 5-Methylcytosine; Computational Biology; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Humans; Isocitrate Dehydrogenase; Janus Kinase 2; Leukemia, Myelomonocytic, Chronic; Mutation; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Proto-Oncogene Proteins; Transcription Factors | 2012 |
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; DNA-Binding Proteins; Humans; Pentoxyl; Thymine DNA Glycosylase | 2012 |
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Humans; Hydroxylation; Mice; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins | 2013 |
Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals.
Topics: 5-Methylcytosine; Ambystoma mexicanum; Amphibians; Animals; Chickens; Cytosine; DNA-Binding Proteins; Humans; Immunohistochemistry; Mammals; Mice; Phylogeny; Tissue Distribution; Xenopus; Zebrafish | 2012 |
5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cell Differentiation; Chick Embryo; Culture Media, Conditioned; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryo, Nonmammalian; Embryonic Development; Embryonic Stem Cells; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; Male; Mice; Organogenesis; Proto-Oncogene Proteins; Time Factors; Vertebrates; Zebrafish | 2012 |
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hippocampus; Male; Mice; Mice, Inbred C57BL; Up-Regulation | 2012 |
Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.
Topics: 5-Methylcytosine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Brain; Cells, Cultured; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Developmental; Laser Capture Microdissection; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Proto-Oncogene Proteins | 2012 |
Autopolyploidy differentially influences body size in plants, but facilitates enhanced accumulation of secondary metabolites, causing increased cytosine methylation.
Topics: 5-Methylcytosine; Biomass; Cymbopogon; Cytosine; Diploidy; DNA Methylation; DNA, Plant; Genome, Plant; Oils, Volatile; Plants; Ploidies; Polyploidy | 2012 |
Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: in vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA.
Topics: 5-Methylcytosine; Arabidopsis Proteins; Cytosine; DNA Methylation; DNA-Binding Proteins; DNA, Plant; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; Escherichia coli; Models, Molecular; Protein Binding; Recombinant Proteins; Spectrometry, Fluorescence; Substrate Specificity | 2012 |
DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells.
Topics: 5-Methylcytosine; Animals; Cell Cycle Proteins; Cell Line; Cytosine; Dimethyl Sulfoxide; DNA (Cytosine-5-)-Methyltransferases; DNA Helicases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Homeodomain Proteins; Mice; Nuclear Proteins; Osteoblasts; Proto-Oncogene Proteins; Repressor Proteins; Stem Cells; Transcription, Genetic | 2012 |
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Genes, Intracisternal A-Particle; High-Throughput Nucleotide Sequencing; Long Interspersed Nucleotide Elements; Mice; Oxidation-Reduction; Rhenium; Sequence Analysis, DNA; Sulfites; Transcription, Genetic; Uracil | 2012 |
Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
Topics: 5-Methylcytosine; Adenine; Binding Sites; Catalytic Domain; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; Endodeoxyribonucleases; Furans; Guanine; Humans; Protein Conformation; Substrate Specificity | 2012 |
Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Line; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; Homeodomain Proteins; Humans; Hydroxylation; Mice; Mice, Knockout; Proto-Oncogene Proteins | 2012 |
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Topics: 5-Methylcytosine; Animals; Cytosine; Embryonic Stem Cells; Epigenomics; Gene Expression Regulation; Genome-Wide Association Study; Genome, Human; Humans; Mice; Sequence Analysis, DNA | 2012 |
Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion.
Topics: 5-Methylcytosine; Animals; Chemokine CXCL10; Cytosine; Dioxygenases; Disease Models, Animal; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation; Kidney; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins; Receptors, Interferon; Reperfusion Injury | 2012 |
Simultaneous determination of global DNA methylation and hydroxymethylation levels by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Topics: 5-Methylcytosine; Animals; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Tandem Mass Spectrometry | 2012 |
Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.
Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cytosine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA-Binding Proteins; Dual-Specificity Phosphatases; Female; Gene Expression Regulation, Enzymologic; Glioblastoma; Glioma; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Male; Mitogen-Activated Protein Kinase Phosphatases; Mixed Function Oxygenases; Mutation; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Subcellular Fractions; Tumor Suppressor Proteins | 2012 |
5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.
Topics: 5-Methylcytosine; Animals; Cell Cycle; Cytosine; DNA Methylation; DNA Replication; Female; Heterochromatin; Male; Mice; Time Factors; Zygote | 2012 |
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.
Topics: 5-Methylcytosine; Animals; Chromatin; Chromosomal Proteins, Non-Histone; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Female; Genomic Imprinting; Histones; Lysine; Male; Methylation; Mice; Protein Binding; Proto-Oncogene Proteins; ras-GRF1; Repressor Proteins; RNA, Long Noncoding; RNA, Untranslated; Spermatozoa | 2012 |
Effect of valproic acid on mitochondrial epigenetics.
Topics: 3T3-L1 Cells; 5-Methylcytosine; Animals; Anticonvulsants; Base Sequence; Benzamides; Cell Nucleus; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA, Mitochondrial; Epigenesis, Genetic; Mice; Mitochondria; Molecular Sequence Data; Pyridines; RNA, Messenger; Valproic Acid | 2012 |
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.
Topics: 3T3-L1 Cells; 5-Methylcytosine; Animals; Binding Sites; Cell Differentiation; Cell Line, Tumor; Chromatin; Cytosine; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Homeodomain Proteins; Mice; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Neurogenesis; Proto-Oncogene Proteins; Transcription Factors | 2012 |
Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.
Topics: 5-Methylcytosine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavioral Symptoms; Benzofurans; Cognition Disorders; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Presenilin-1; Quinolines; Space Perception; Stress, Psychological | 2013 |
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.
Topics: 5-Methylcytosine; Brain; Cell Differentiation; Cytosine; Glioma; Humans; Immunohistochemistry; Neurons; Stem Cells | 2012 |
Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
Topics: 5-Methylcytosine; Bacteria; Catalytic Domain; Cytosine; DNA; Endodeoxyribonucleases; Humans; Models, Molecular; Pentoxyl; Protein Structure, Tertiary; Substrate Specificity; Thymine; Thymine DNA Glycosylase | 2012 |
New sequencing technique produces high-resolution map of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA; Embryonic Stem Cells; Epigenesis, Genetic; Mice; Nucleotide Mapping; Rhenium; Sequence Analysis, DNA | 2012 |
Differential effect of three base modifications on DNA thermostability revealed by high resolution melting.
Topics: 5-Methylcytosine; Adenine; Cluster Analysis; Cytosine; DNA; Nucleic Acid Denaturation; Phase Transition; Principal Component Analysis; Transition Temperature | 2012 |
Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator.
Topics: 5-Methylcytosine; Animals; Ants; CpG Islands; Cytosine; DNA Methylation; DNA Transposable Elements; Epigenesis, Genetic; Exons; Gene Expression Regulation; Gene Expression Regulation, Developmental; Genome, Insect; RNA Splice Sites; Transcriptome | 2012 |
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Line; Chromosome Mapping; Computational Biology; CpG Islands; Cytosine; Dioxygenases; DNA Repair; DNA-Binding Proteins; Down-Regulation; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Genome; High-Throughput Nucleotide Sequencing; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; Thymine DNA Glycosylase; Transcription, Genetic | 2012 |
CpG site-specific alteration of hydroxymethylcytosine to methylcytosine beyond DNA replication.
Topics: 5-Methylcytosine; Base Sequence; CpG Islands; Cytosine; DNA Methylation; DNA Replication; Genetic Vectors; HEK293 Cells; Humans; Polymerase Chain Reaction | 2012 |
[Analysis of global deoxyribonucleic acid 5-hydroxymethylcytosine in tissue by liquid chromatography-tandem mass spectrometry].
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; Rats; Tandem Mass Spectrometry | 2012 |
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.
Topics: 5-Methylcytosine; Alternative Splicing; Animals; Brain; Cell Line; Cytosine; Glucosyltransferases; Humans; Introns; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Organ Specificity; Reproducibility of Results; RNA Splicing; Synapses | 2012 |
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Isocitrate Dehydrogenase; Melanocytes; Melanoma; Nevus; Proto-Oncogene Proteins | 2012 |
Sequencing the sixth base (5-hydroxymethylcytosine): selective DNA oxidation enables base-pair resolution.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; Deamination; DNA; Oxidation-Reduction; Sequence Analysis, DNA; Sulfites | 2012 |
The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Antibodies; Base Sequence; Cytosine; DNA Primers; Genomics; Immunoprecipitation; Molecular Sequence Data; Sulfites | 2012 |
The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Biotinylation; Cytosine; Genomics; Glucose; Molecular Sequence Data; Oxidation-Reduction; Periodic Acid | 2012 |
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenomics; Gene Expression Profiling; Gene Expression Regulation; Histones; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Phenobarbital; Promoter Regions, Genetic | 2012 |
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.
Topics: 5-Methylcytosine; Adult; Cerebellum; CpG Islands; Cytosine; DNA; DNA Methylation; DNA, Intergenic; Epigenesis, Genetic; Female; Fragile X Mental Retardation Protein; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genome-Wide Association Study; Genome, Human; Genomics; Humans; Male; RNA, Messenger; Sequence Alignment | 2012 |
Selective capture of 5-hydroxymethylcytosine from genomic DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; Genome, Human; Humans | 2012 |
Balance of DNA methylation and demethylation in cancer development.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Liver; Male; Phenobarbital | 2012 |
Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells.
Topics: 5-Methylcytosine; Animals; Bromodeoxyuridine; Cell Line; Chromosomes, Human, X; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Euchromatin; Female; Gene Deletion; Gene Expression Regulation; Gene Silencing; Genetic Markers; Genomic Imprinting; Heterochromatin; Histones; Humans; In Situ Hybridization, Fluorescence; Male; Mice; Retroelements; Sequence Analysis, DNA | 2012 |
Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin.
Topics: 5-Methylcytosine; Animals; Chromatin; Chromosomes; Cytosine; DNA; DNA Methylation; Gene Expression Regulation; Humans; Immunoblotting; Methyl-CpG-Binding Protein 2; Mutation; Oocytes; RNA Polymerase II; Sequence Analysis, DNA; Transcription, Genetic; Xenopus laevis | 2012 |
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA-Binding Proteins; Glucosyltransferases; Mice; Polymerase Chain Reaction; Proto-Oncogene Proteins; Sequence Analysis, DNA; Sulfites | 2012 |
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Epigenesis, Genetic; Female; Genomic Imprinting; Germ Cells; Germ Layers; Male; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA-Binding Proteins | 2013 |
Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Line; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Mice; Octamer Transcription Factor-3; Proto-Oncogene Proteins; Pyrazoles; Pyrimidines | 2013 |
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Topics: 5-Methylcytosine; Animals; Cerebellum; Chromatin; Cytosine; Epigenesis, Genetic; Humans; Methyl-CpG-Binding Protein 2; Mice; Mice, Knockout; Neuroglia; Neurons; Purkinje Cells; Rett Syndrome | 2012 |
Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4.
Topics: 5-Methylcytosine; Animals; Crystallography, X-Ray; Cytosine; DNA Methylation; Endodeoxyribonucleases; Humans; Mice; Protein Structure, Tertiary; Structure-Activity Relationship | 2013 |
Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.
Topics: 5-Methylcytosine; Biomarkers; Carcinoma, Hepatocellular; Chromatography, Liquid; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Limit of Detection; Liver Neoplasms; Sequence Analysis, DNA; Tandem Mass Spectrometry | 2013 |
High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Line; Chromosome Mapping; Computational Biology; CpG Islands; Cytosine; DNA Methylation; DNA Restriction Enzymes; Embryonic Stem Cells; Genomics; Histones; Hydroxylation; Mice; Sequence Analysis, DNA | 2013 |
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Embryonic Stem Cells; Epigenesis, Genetic; Female; Fertility; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Genomic Imprinting; Humans; Hydroxylation; Male; Mice; Proto-Oncogene Proteins | 2013 |
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; CpG Islands; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Glycosylation; Histone-Lysine N-Methyltransferase; Histones; Host Cell Factor C1; Humans; Immunoprecipitation; Mice; Mice, Knockout; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Transcription, Genetic | 2013 |
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease.
Topics: 5-Methylcytosine; 5' Untranslated Regions; Adult; Aged; Aged, 80 and over; Animals; Corpus Striatum; Cytosine; Disease Models, Animal; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins; Putamen; Receptor, Adenosine A2A | 2013 |
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases.
Topics: 5-Methylcytosine; Animals; Calcium; Cell Nucleus; Chromatography, Thin Layer; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Genomics; HEK293 Cells; Humans; Ions; Male; Mice; Oxidation-Reduction; Signal Transduction; Spermatozoa; Swine | 2013 |
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Germ Cells; Heterochromatin; Male; Mice | 2013 |
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Chromatin; Cytosine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenomics; Histones; Mice; Neurogenesis; Neurons; Oxidation-Reduction; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; RNA, Small Interfering | 2013 |
A sweet TET-à-tête-synergy of TET proteins and O-GlcNAc transferase in transcription.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mixed Function Oxygenases; N-Acetylglucosaminyltransferases; Proto-Oncogene Proteins; Transcription, Genetic | 2013 |
Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method.
Topics: 5-Methylcytosine; Animals; Cell Lineage; Cells, Cultured; Cytosine; DNA Methylation; Embryonic Stem Cells; Gene Expression; Genome; High-Throughput Nucleotide Sequencing; Immunoprecipitation; Mice; Neural Stem Cells; Sequence Analysis, DNA | 2013 |
Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Genome; Germ Cells; Green Fluorescent Proteins; Mice; Proto-Oncogene Proteins | 2013 |
Early de novo DNA methylation and prolonged demethylation in the muscle lineage.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Myosins; Case-Control Studies; CCCTC-Binding Factor; Cell Lineage; Child; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genes, Homeobox; Genome, Human; Guanine Nucleotide Exchange Factors; Histones; Humans; Infant, Newborn; Male; Middle Aged; Mixed Function Oxygenases; Muscle Development; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Dystrophy, Facioscapulohumeral; Myoblasts; Myosin Heavy Chains; Paired Box Transcription Factors; PAX3 Transcription Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Repressor Proteins; Rho Guanine Nucleotide Exchange Factors; T-Box Domain Proteins; Transcription, Genetic | 2013 |
Decreased 5-hydroxymethylcytosine levels are associated with TET2 mutation and unfavorable overall survival in myelodysplastic syndromes.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Prognosis; Proto-Oncogene Proteins; Young Adult | 2013 |
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA Glycosylases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Kruppel-Like Factor 4; Mass Spectrometry; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Regulatory Factor X Transcription Factors; Stem Cells; Transcription Factors; Ubiquitin-Protein Ligases | 2013 |
Number of manic episodes is associated with elevated DNA oxidation in bipolar I disorder.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Bipolar Disorder; Cytosine; Deoxyguanosine; DNA; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Multivariate Analysis; Oxidation-Reduction; Oxidative Stress; Young Adult | 2013 |
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Base Sequence; Cell Fusion; Cell Line; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression; Genomic Imprinting; Germ Cells; Green Fluorescent Proteins; Humans; Insulin-Like Growth Factor II; Mice; Molecular Sequence Data; Octamer Transcription Factor-3; Polymorphism, Single Nucleotide; Proteins; Proto-Oncogene Proteins; RNA, Long Noncoding; Sequence Analysis, DNA | 2013 |
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Proteins; Epigenomics; Humans; Melanoma; Paraffin Embedding; Proto-Oncogene Proteins; Skin Neoplasms; Translocation, Genetic | 2013 |
Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases.
Topics: 5-Methylcytosine; Bacteriophage T4; Cytosine; DNA Cleavage; DNA Restriction Enzymes; DNA, Viral; Glucosyltransferases; Sequence Homology, Amino Acid; Substrate Specificity | 2013 |
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.
Topics: 5-Methylcytosine; Animals; Cellular Reprogramming; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Enhancer Elements, Genetic; Gene Expression Regulation, Developmental; Induced Pluripotent Stem Cells; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Models, Biological; Octamer Transcription Factor-3; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; SOXB1 Transcription Factors; Transcription, Genetic; Transcriptome | 2013 |
Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cells, Cultured; Cytosine; DNA Methylation; Embryoid Bodies; Embryonic Stem Cells; High-Throughput Screening Assays; Humans; Mice; Sequence Analysis, DNA | 2013 |
Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line.
Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatography, Liquid; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Tandem Mass Spectrometry | 2013 |
Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Ascorbic Acid; Cells, Cultured; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Knockdown Techniques; Hydroxylation; Mice; Mice, Inbred C57BL; Phloretin; Proto-Oncogene Proteins; RNA, Small Interfering | 2013 |
Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis.
Topics: 5-Methylcytosine; Cytosine; DNA; Molecular Structure; Nanopores | 2013 |
GSE is a maternal factor involved in active DNA demethylation in zygotes.
Topics: 5-Methylcytosine; Animals; Blastocyst; Chromatin; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Development; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Homeodomain Proteins; Long Interspersed Nucleotide Elements; Male; Mice; Nanog Homeobox Protein; Octamer Transcription Factor-3; Protein Binding; Proteins; RNA, Small Interfering; Sex Factors; Zygote | 2013 |
Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells.
Topics: 5-Methylcytosine; Animals; Biomarkers; Cell Differentiation; Cells, Cultured; Cytosine; DNA; DNA Methylation; Fluorescent Antibody Technique; Humans; Imaging, Three-Dimensional; Indoles; Mice; Microscopy, Confocal; Proteins; Stem Cells | 2013 |
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.
Topics: 5-Methylcytosine; Animals; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytosine; DNA Methylation; Epigenesis, Genetic; Genetic Markers; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Phenobarbital; Promoter Regions, Genetic; Transcriptome | 2013 |
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA Repair; Embryonic Stem Cells; Epigenesis, Genetic; Genetic Techniques; Genome-Wide Association Study; Heterochromatin; Mice; Oxidation-Reduction; Regulatory Elements, Transcriptional; Thymine DNA Glycosylase | 2013 |
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
Topics: 5-Methylcytosine; Animals; Cytosine; Embryonic Stem Cells; Epigenesis, Genetic; Genetic Techniques; Genome-Wide Association Study; Mice; p300-CBP Transcription Factors; Regulatory Elements, Transcriptional | 2013 |
A convenient method for selective detection of 5-hydroxymethylcytosine and 5-formylcytosine sites in DNA sequences.
Topics: 5-Methylcytosine; Base Sequence; Chromatography, High Pressure Liquid; Combinatorial Chemistry Techniques; Cytosine; Electrophoresis, Gel, Two-Dimensional; Sequence Analysis, DNA | 2013 |
First evidence of DNA methylation in insect Tribolium castaneum: environmental regulation of DNA methylation within heterochromatin.
Topics: 5-Methylcytosine; Animals; Base Sequence; Blotting, Southern; Cytosine; DNA Methylation; DNA, Satellite; Electrophoresis, Agar Gel; Environment; Genome, Insect; Heterochromatin; Molecular Sequence Data; Tribolium | 2013 |
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease.
Topics: 5-Methylcytosine; Animals; Brain; Corpus Striatum; Cytosine; Disease Models, Animal; DNA Methylation; Epigenomics; Humans; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Sequence Alignment; Sequence Analysis, DNA | 2013 |
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine; Diethylnitrosamine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins; Rats, Wistar | 2013 |
Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.
Topics: 5-Methylcytosine; Cell Differentiation; Cell Line, Tumor; Cytosine; DNA Methylation; Epigenomics; Female; Histones; Humans; In Vitro Techniques; Male; Neoplasms; Polycomb-Group Proteins | 2013 |
Formation of cyclobutane pyrimidine dimers at dipyrimidines containing 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Base Sequence; Cells, Cultured; Cytosine; DNA; Fibroblasts; Humans; Keratinocytes; Melanocytes; Pyrimidine Dimers; Ultraviolet Rays | 2013 |
Hydrophilic material for the selective enrichment of 5-hydroxymethylcytosine and its liquid chromatography-tandem mass spectrometry detection.
Topics: 5-Methylcytosine; Chromatography, Liquid; Cytosine; HEK293 Cells; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Jurkat Cells; Tandem Mass Spectrometry | 2013 |
Prognostic role of immunohistochemical analysis of 5 mc in myelodysplastic syndromes.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Bone Marrow; Bone Marrow Cells; Cell Lineage; Cytosine; DNA Methylation; Female; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Sequence Analysis, DNA | 2013 |
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency.
Topics: 5-Methylcytosine; Cell Differentiation; Cell Line; Cellular Reprogramming; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Enzyme Activation; Epigenesis, Genetic; Fibroblasts; Humans; Induced Pluripotent Stem Cells; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA Interference; RNA, Small Interfering; Sequence Alignment; Transcription Factors | 2013 |
5'-Methylcytosine and 5'-hydroxymethylcytosine each provide epigenetic information to the mouse zygote.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Cytosine; Dose-Response Relationship, Drug; Epigenesis, Genetic; Female; Male; Mice; Solvents; Temperature; Zygote | 2013 |
Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter.
Topics: 5-Methylcytosine; Animals; Animals, Newborn; Cytosine; Dietary Proteins; DNA Methylation; DNA, Mitochondrial; Electron Transport Complex IV; Epigenesis, Genetic; Female; Liver; Male; Mothers; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; RNA, Messenger; Sex Characteristics; Swine; Transcription, Genetic | 2013 |
5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytes.
Topics: 5-Methylcytosine; Cell Differentiation; Cytosine; Dendritic Cells; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Knockdown Techniques; Humans; Mass Spectrometry; Monocytes; Proto-Oncogene Proteins | 2013 |
Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway.
Topics: 5-Methylcytosine; Animals; Cytosine; Embryonic Stem Cells; Epigenesis, Genetic; Genetic Techniques; Genome-Wide Association Study | 2013 |
5-methyl-cytosine and 5-hydroxy-methyl-cytosine in the genome of Biomphalaria glabrata, a snail intermediate host of Schistosoma mansoni.
Topics: 5-Methylcytosine; Animals; Biomphalaria; Chemistry Techniques, Analytical; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic | 2013 |
Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA Mutational Analysis; Down-Regulation; Electron Transport Complex II; Exons; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Membrane Proteins; Mutation; Phenotype; Proto-Oncogene Proteins c-kit; Receptor, Platelet-Derived Growth Factor alpha; Succinate Dehydrogenase | 2013 |
Optical detection of epigenetic marks: sensitive quantification and direct imaging of individual hydroxymethylcytosine bases.
Topics: 5-Methylcytosine; Animals; Bacteriophage lambda; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Fluorescent Dyes; Mice; Models, Molecular; Optical Imaging | 2013 |
Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis.
Topics: 5-Methylcytosine; Animals; Cell Separation; Cell Shape; Chromatin; Chromosomes, Mammalian; Cytosine; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Profiling; Genome; Male; Mice; Microscopy, Phase-Contrast; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Sex Chromosomes; Spermatogenesis; Spermatozoa; Transcriptome; Up-Regulation | 2013 |
Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Single-Stranded; Nanopores; Sequence Analysis, DNA | 2013 |
Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels.
Topics: 5-Methylcytosine; Adult; Age Factors; Aging; Cytosine; DNA; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Humans; Male; Middle Aged; Paternal Age; Prospective Studies; Risk Factors; Spermatozoa; Up-Regulation | 2013 |
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Topics: 5-Methylcytosine; Animals; Antioxidants; Ascorbic Acid; Blastocyst; Cell Line; Culture Media; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Mice; Protein Binding; Proto-Oncogene Proteins; Recombinant Proteins | 2013 |
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Topics: 5-Methylcytosine; Chromatin Immunoprecipitation; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Homeodomain Proteins; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Microarray Analysis; Mixed Function Oxygenases; Myeloid Ecotropic Viral Integration Site 1 Protein; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins; Signal Transduction; Tandem Mass Spectrometry | 2013 |
-Oh no! hiPSCs misplace their 5hmCs.
Topics: 5-Methylcytosine; Cytosine; DNA-Binding Proteins; Humans; Induced Pluripotent Stem Cells; Proto-Oncogene Proteins | 2013 |
Global epigenomic reconfiguration during mammalian brain development.
Topics: 5-Methylcytosine; Adult; Animals; Base Sequence; Conserved Sequence; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenomics; Frontal Lobe; Gene Expression Regulation, Developmental; Genome-Wide Association Study; Humans; Longevity; Mice; Mice, Inbred C57BL; X Chromosome Inactivation | 2013 |
Paternal age and sperm methylation status.
Topics: 5-Methylcytosine; Aging; Cytosine; DNA; DNA Methylation; Humans; Male; Paternal Age; Spermatozoa | 2013 |
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Chromatin Assembly and Disassembly; Cytosine; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; MicroRNAs; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Proto-Oncogene Proteins; RNA Interference; Transplantation, Heterologous | 2013 |
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA, Neoplasm; Gene Expression; Genome, Human; Genomics; Glycosyltransferases; Humans; Mice; Pancreatic Neoplasms; Polymerase Chain Reaction | 2013 |
Dynamics of DNA demethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; Embryonic Stem Cells; Epigenesis, Genetic; Genetic Techniques; Genome-Wide Association Study | 2013 |
Transient reduction of 5-methylcytosine and 5-hydroxymethylcytosine is associated with active DNA demethylation during regeneration of zebrafish fin.
Topics: 5-Methylcytosine; Animal Fins; Animals; Animals, Genetically Modified; Cell Dedifferentiation; Cytosine; DNA Methylation; DNA Repair; Embryo, Nonmammalian; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Regeneration; Zebrafish | 2013 |
PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine.
Topics: 3T3-L1 Cells; 5-Methylcytosine; Adipocytes; Adipose Tissue; Amino Acid Sequence; Animals; Base Sequence; Cell Differentiation; Cytosine; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; HEK293 Cells; Humans; Hydroxylation; Mice; Molecular Sequence Data; Phenanthrenes; Poly Adenosine Diphosphate Ribose; PPAR gamma; Protein Binding; Proto-Oncogene Proteins; Response Elements | 2013 |
Genetics. The maturing brain methylome.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Frontal Lobe; Gene Expression Regulation, Developmental; Humans | 2013 |
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase.
Topics: 5-Methylcytosine; Cell Cycle; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation; Genome, Human; HEK293 Cells; Humans; Hydroquinones; Mixed Function Oxygenases; Proto-Oncogene Proteins; Reactive Oxygen Species | 2013 |
Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function.
Topics: 5-Methylcytosine; Adult; Age Factors; Carbohydrate Metabolism; Cytosine; DNA Methylation; Epigenesis, Genetic; Fetus; Gene Expression Regulation, Developmental; Genome, Human; Hepatocytes; Humans; Inactivation, Metabolic; Lipid Metabolism; Liver; Molecular Sequence Annotation; Protein Biosynthesis | 2013 |
Crystal structures of B-DNA dodecamer containing the epigenetic modifications 5-hydroxymethylcytosine or 5-methylcytosine.
Topics: 5-Methylcytosine; Cations; Crystallography, X-Ray; Cytosine; DNA, B-Form; Epigenesis, Genetic; Models, Molecular; Thermodynamics; Water | 2013 |
MLML: consistent simultaneous estimates of DNA methylation and hydroxymethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; High-Throughput Nucleotide Sequencing; Sequence Analysis, DNA; Software | 2013 |
Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Olfactory Bulb; Olfactory Mucosa; Olfactory Receptor Neurons; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy.
Topics: 5-Methylcytosine; Azacitidine; Cell Hypoxia; Cytosine; Decitabine; DNA; DNA Modification Methylases; DNA-Binding Proteins; HeLa Cells; Humans; Single-Cell Analysis; Spectrometry, Fluorescence | 2013 |
Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; China; Cytosine; Female; Humans; Incidence; Male; Middle Aged; Prognosis; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Stomach Neoplasms; Survival Analysis; Survival Rate | 2013 |
Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine.
Topics: 5-Methylcytosine; Carboxylic Acids; Cytosine; Deamination; Oxidation-Reduction; Sulfhydryl Compounds | 2013 |
Reactivation of Х chromosome upon reprogramming leads to changes in the replication pattern and 5hmC accumulation.
Topics: 5-Methylcytosine; Animals; Cell Line; Cellular Reprogramming; Chromosomes, Human, X; Cytosine; DNA Replication; DNA Replication Timing; Female; Gene Expression Regulation; Humans; Induced Pluripotent Stem Cells; Mice; X Chromosome Inactivation | 2014 |
Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Adult Stem Cells; Animals; Cell Differentiation; Chromatin; Cytosine; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation; Genome; Histones; Mice; Pluripotent Stem Cells; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Proto-Oncogene Proteins; Repressor Proteins; RNA, Small Interfering; Sin3 Histone Deacetylase and Corepressor Complex; Transcription, Genetic | 2013 |
Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Nucleus; Cells, Cultured; Chromosomes, Mammalian; Cytosine; DNA Methylation; DNA, Satellite; Embryonic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Male; Mice; Spermatozoa | 2013 |
Fluorescent strategy based on cationic conjugated polymer fluorescence resonance energy transfer for the quantification of 5-(hydroxymethyl)cytosine in genomic DNA.
Topics: 5-Methylcytosine; Animals; Cations; Chromatography, High Pressure Liquid; Cytosine; DNA; Embryonic Stem Cells; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HEK293 Cells; HeLa Cells; Humans; Mice; Oxidation-Reduction; Polymers; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity | 2013 |
DNA methylation: an identity card for brain cells.
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA Methylation; Epigenesis, Genetic; Genome; Humans; Mice; Neuroglia; Neurons; Organ Specificity | 2013 |
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Oxidation-Reduction; Sequence Analysis, DNA | 2013 |
Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate.
Topics: 5-Methylcytosine; Animals; Ascorbic Acid; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Fibroblasts; Iron; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins; Sodium-Coupled Vitamin C Transporters | 2013 |
Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus.
Topics: 5-Methylcytosine; 5' Untranslated Regions; Adolescent; Adult; CCCTC-Binding Factor; Cerebellum; Cytosine; DNA Methylation; Frataxin; Friedreich Ataxia; Genetic Loci; Humans; Iron-Binding Proteins; Microsatellite Repeats; Middle Aged; Myocardium; Protein Binding; Repressor Proteins; Young Adult | 2013 |
PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation.
Topics: 5-Methylcytosine; Binding Sites; Cell Differentiation; CpG Islands; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Monocytes; NF-kappa B; Osteoclasts; Protein Binding; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins; RNA, Small Interfering; Trans-Activators; Transcription Factor AP-1 | 2013 |
Systematic investigation of DNAs with modified cytosines under hot alkali treatment.
Topics: 5-Methylcytosine; Alkalies; Cytosine; DNA; Hot Temperature; Molecular Structure | 2013 |
Mutagenic and cytotoxic properties of oxidation products of 5-methylcytosine revealed by next-generation sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Escherichia coli; High-Throughput Nucleotide Sequencing; Oxidation-Reduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Intronic non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees.
Topics: 5-Methylcytosine; Africa; Alternative Splicing; Animals; Bees; Behavior, Animal; CpG Islands; Cytosine; DNA Methylation; Europe; Exons; Gene Expression Regulation; Genes, Insect; Honey; Introns; Reproducibility of Results; RNA Splice Sites; RNA, Messenger; Sequence Analysis, DNA; Sulfites | 2013 |
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage.
Topics: 5-Methylcytosine; Cell Differentiation; Cell Lineage; Cells, Cultured; Cytosine; DNA Methylation; Embryonic Stem Cells; Gene Expression Regulation; Gene Silencing; GPI-Linked Proteins; Homeodomain Proteins; Humans; Mesoderm; Nerve Tissue Proteins; Neurogenesis; Neurons; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; RANK Ligand; Receptor, Notch1; Transcription Factors | 2014 |
Evaluation of UDP-GlcN derivatives for selective labeling of 5-(hydroxymethyl)cytosine.
Topics: 5-Methylcytosine; Animals; Antibodies; Bacteriophage T4; Cytosine; DNA; Embryonic Stem Cells; Fluorescent Dyes; Glucosamine; Glucosyltransferases; Glycosylation; Mice; Oligonucleotides; Staining and Labeling; Substrate Specificity; Uracil Nucleotides | 2013 |
Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome.
Topics: 5-Methylcytosine; Animals; Ataxia; Base Sequence; Cerebellum; Consensus Sequence; Cytosine; Disease Models, Animal; DNA Methylation; Fragile X Syndrome; Humans; Mice; Mice, Transgenic; Terminator Regions, Genetic; Transcription Initiation Site; Tremor | 2014 |
MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Flow Cytometry; Gene Expression Regulation, Developmental; Islets of Langerhans; Luciferases; Mice; Mice, Transgenic; Microfluidics; MicroRNAs; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Thymine DNA Glycosylase | 2013 |
An extensive network of TET2-targeting MicroRNAs regulates malignant hematopoiesis.
Topics: 3' Untranslated Regions; 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Hematologic Neoplasms; Hematopoiesis; Humans; Mice; MicroRNAs; Phenotype; Proto-Oncogene Proteins | 2013 |
Loss of 5-hydroxymethylcytosine and TET2 in oral squamous cell carcinoma.
Topics: 5-Methylcytosine; Carcinoma, Squamous Cell; Case-Control Studies; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mouth Mucosa; Mouth Neoplasms; Proto-Oncogene Proteins | 2013 |
Association of 5-methylcytosine and 5-hydroxymethylcytosine with mitochondrial DNA content and clinical and biochemical parameters in hepatocellular carcinoma.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Cytosine; DNA, Mitochondrial; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Risk Factors; Tumor Burden; Young Adult | 2013 |
Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence.
Topics: 5-Methylcytosine; Cytosine; Hot Temperature; Hydrogen Bonding; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; X-Ray Diffraction | 2013 |
Hydroxymethylated DNA immunoprecipitation (hmeDIP).
Topics: 5-Methylcytosine; Antibody Specificity; Brain; Breast; Cytosine; DNA; DNA Fragmentation; Epitopes; Female; Humans; Immunoprecipitation; Sonication | 2014 |
Cytosine DNA methylation influences drug resistance in Escherichia coli through increased sugE expression.
Topics: 5-Methylcytosine; Azacitidine; Bacterial Proteins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ethidium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Membrane Proteins; Microbial Sensitivity Tests; Molecular Chaperones; Sigma Factor | 2014 |
Detection and mapping of 5-methylcytosine and 5-hydroxymethylcytosine with nanopore MspA.
Topics: 5-Methylcytosine; Bayes Theorem; Cytosine; DNA Methylation; Epigenomics; Models, Molecular; Molecular Structure; Nanopores; Porins | 2013 |
Error rates for nanopore discrimination among cytosine, methylcytosine, and hydroxymethylcytosine along individual DNA strands.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Epigenomics; Nanopores; Research Design | 2013 |
5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Humans; Keratinocytes; Male; Melanoma; Middle Aged; Nevus, Epithelioid and Spindle Cell; Nevus, Pigmented; Skin Neoplasms | 2014 |
A novel combined bisulfite UDG assay for selective 5-methylcytosine detection.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Cleavage; DNA Methylation; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Humans; Oligodeoxyribonucleotides; Sensitivity and Specificity; Sequence Analysis, DNA; Sodium Hydroxide; Solutions; Sulfites; Uracil; Uracil-DNA Glycosidase | 2013 |
Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques.
Topics: 5-Methylcytosine; Animals; Antibodies; Chromatin; CpG Islands; Cytosine; DNA; DNA-Binding Proteins; Genetic Loci; Genomic Imprinting; Immunoassay; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Tandem Repeat Sequences | 2013 |
Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.
Topics: 5-Methylcytosine; Animals; Apoferritins; Cell Line; Cell Line, Tumor; Chloranil; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation; Genome; Humans; Iron; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Quinones | 2014 |
DNA recognition of 5-carboxylcytosine by a Zfp57 mutant at an atomic resolution of 0.97 Å.
Topics: 5-Methylcytosine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Computational Biology; Crystallography, X-Ray; Cytosine; DNA; Glutamic Acid; Glutamine; Kinetics; Mice; Models, Molecular; Molecular Conformation; Mutant Proteins; Recombinant Proteins; Repressor Proteins; Zinc; Zinc Fingers | 2013 |
Large conserved domains of low DNA methylation maintained by Dnmt3a.
Topics: 5-Methylcytosine; Animals; Base Sequence; Conserved Sequence; CpG Islands; Cytosine; Databases, Genetic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Gene Expression Regulation; Hematopoietic Stem Cells; Histones; Humans; Leukemia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains | 2014 |
Structural insights into how 5-hydroxymethylation influences transcription factor binding.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Models, Molecular; Nucleic Acid Conformation; Oxidation-Reduction; Protein Binding; Transcription Factors | 2014 |
Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine in DNA by selective chemical labeling.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; DNA; Models, Molecular; Molecular Structure | 2014 |
Dynamic reprogramming of 5-hydroxymethylcytosine during early porcine embryogenesis.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Embryonic Development; Nuclear Transfer Techniques; Swine | 2014 |
Understanding variation in transcription factor binding by modeling transcription factor genome-epigenome interactions.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Embryonic Stem Cells; Epigenomics; Genome; Histones; Mice; Models, Biological; Protein Binding; Transcription Factors | 2013 |
Cell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cell Proliferation; Cell Separation; CpG Islands; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Replication; Embryonic Stem Cells; Flow Cytometry; Mice; Mice, Knockout; Multigene Family; Nuclear Proteins; Promoter Regions, Genetic; Protein Structure, Tertiary; Ubiquitin-Protein Ligases | 2013 |
Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor.
Topics: 5-Methylcytosine; Algorithms; Biological Transport; Biosensing Techniques; Cytosine; DNA; DNA Damage; DNA, Single-Stranded; Escherichia coli; Ions; Lipid Bilayers; Molecular Dynamics Simulation; Nanopores; Nanotechnology; Nanotubes, Carbon; Thermodynamics | 2013 |
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.
Topics: 5-Methylcytosine; Animals; Binding Sites; CCCTC-Binding Factor; Cell Differentiation; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation; Genome; Mice; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Transcription Factors; Transcription, Genetic | 2013 |
Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells.
Topics: 5-Methylcytosine; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Differentiation; Cytosine; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Developmental; Humans; Pluripotent Stem Cells; Signal Transduction; Transcription Factors | 2013 |
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Topics: 5-Methylcytosine; Antigens, CD34; Cells, Cultured; Cytosine; Dioxygenases; DNA Methylation; Erythroid Cells; Erythropoiesis; Histones; Humans; Mutation; Regulatory Sequences, Nucleic Acid; Transcription Factors | 2014 |
Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.
Topics: 5-Methylcytosine; Carcinoma; Cell Line, Tumor; Cytosine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Germ Cells; Humans; Immunohistochemistry; Male; Mixed Function Oxygenases; Neoplasms, Germ Cell and Embryonal; Oxidation-Reduction; Proto-Oncogene Proteins; Spermatogenesis; Testis | 2013 |
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Genetic Markers; Humans; Male; Microglia; Middle Aged; Neurons; Parahippocampal Gyrus | 2014 |
Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; Female; Humans; Male; Melanoma; Middle Aged; Nevus; Precancerous Conditions; Skin Neoplasms; Young Adult | 2014 |
Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Cytosine; Dioxygenases; DNA; DNA-Binding Proteins; Escherichia coli Proteins; HEK293 Cells; Humans; Hydrogen Bonding; Mice; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Naegleria; Proto-Oncogene Proteins; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2014 |
Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).
Topics: 5-Methylcytosine; Active Transport, Cell Nucleus; Cell Nucleus; Cytosine; Dioxygenases; DNA Methylation; Glucose; HeLa Cells; Humans; N-Acetylglucosaminyltransferases | 2014 |
Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence.
Topics: 5-Methylcytosine; Animals; Base Sequence; CpG Islands; Cytosine; Disease Models, Animal; Epigenomics; Genome-Wide Association Study; Hypertension; Kidney Medulla; Male; Phenotype; Rats; Rats, Inbred Dahl; RNA, Messenger; Sodium Chloride, Dietary; Transcriptome | 2014 |
Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum.
Topics: 5-Methylcytosine; Cell Adhesion Molecules, Neuronal; Cerebellar Cortex; Child Development Disorders, Pervasive; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Extracellular Matrix Proteins; Glutamate Decarboxylase; Humans; Methyl-CpG-Binding Protein 2; Mixed Function Oxygenases; Nerve Tissue Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reelin Protein; Serine Endopeptidases; Tissue Banks | 2014 |
A global increase in 5-hydroxymethylcytosine levels marks osteoarthritic chondrocytes.
Topics: 5-Methylcytosine; ADAM Proteins; ADAMTS5 Protein; Adolescent; Adult; Aged; Aged, 80 and over; Anterior Cruciate Ligament Reconstruction; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Case-Control Studies; Child; Child, Preschool; Chondrocytes; CpG Islands; Cytokines; Cytosine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Female; Gene Expression; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Middle Aged; Mixed Function Oxygenases; Osteoarthritis, Knee; Promoter Regions, Genetic; Proto-Oncogene Proteins; Young Adult | 2014 |
Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process.
Topics: 5-Methylcytosine; Animals; Carcinoma, Hepatocellular; Cell Dedifferentiation; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cytosine; DNA Methylation; ELAV Proteins; ELAV-Like Protein 2; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Vectors; HEK293 Cells; Homeodomain Proteins; Humans; Lentivirus; Liver; Liver Neoplasms; Metabolomics; Mice; MicroRNAs; Nanog Homeobox Protein; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Pluripotent Stem Cells; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Serum Albumin; Serum Albumin, Human; Telomerase; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2014 |
Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, α-Ketoglutarate (α-KG), and DNA hydroxymethylation levels by interleukin-1β in primary human chondrocytes.
Topics: 5-Methylcytosine; Chondrocytes; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Interleukin-1beta; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mixed Function Oxygenases; Primary Cell Culture; Proto-Oncogene Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha | 2014 |
Protein nanopores to detect DNA methylation.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Epigenomics; Models, Molecular; Nanopores; Porins | 2014 |
Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.
Topics: 5-Methylcytosine; Animals; Brain; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Genetic Loci; Genome; Genome, Human; Humans; Macaca mulatta; Mice; Oligonucleotide Array Sequence Analysis | 2014 |
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.
Topics: 5-Methylcytosine; Adult; Brain; CpG Islands; Cytosine; DNA Methylation; DNA, Antisense; Exons; Female; Gene Expression Regulation, Developmental; Genome, Human; Histones; Humans; Introns; Male; Transcription, Genetic | 2014 |
DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation.
Topics: 5-Methylcytosine; Cell Line, Tumor; CpG Islands; Cyclin-Dependent Kinase Inhibitor p21; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; HeLa Cells; Humans; Protein Binding; Repressor Proteins | 2014 |
Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Animals, Newborn; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Humans; Mice; Mixed Function Oxygenases; Molecular Sequence Data; Oligodendroglia; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley | 2014 |
TET proteins and 5-methylcytosine oxidation in the immune system.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Profiling; Humans; Immunoprecipitation; Mice; Mixed Function Oxygenases; Oxidoreductases; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins | 2013 |
DNA counterstaining for methylation and hydroxymethylation immunostaining in bovine zygotes.
Topics: 5-Methylcytosine; Animals; Cattle; Cytosine; DNA Methylation; Staining and Labeling; Zygote | 2014 |
Determination of global DNA methylation level by capillary electrophoresis using octyl-modified quaternized cellulose as an electrolyte additive.
Topics: 5-Methylcytosine; Cellulose; Cytosine; DNA; DNA Methylation; Electrolytes; Electrophoresis, Capillary; Hydrolysis | 2014 |
Crystal structure of the 5hmC specific endonuclease PvuRts1I.
Topics: 5-Methylcytosine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Bacteriophage T4; Catalytic Domain; Crystallography, X-Ray; Cytosine; DNA Restriction Enzymes; DNA, Viral; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Secondary; Proteus vulgaris; Substrate Specificity | 2014 |
A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine.
Topics: 5-Methylcytosine; Agaricales; Cytosine; Dioxygenases; Fungal Proteins | 2014 |
Hydroxymethylation and DNA methylation profiles in the prefrontal cortex of the non-human primate rhesus macaque and the impact of maternal deprivation on hydroxymethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; Databases, Genetic; DNA Methylation; Epigenesis, Genetic; Frontal Lobe; Gene Expression; Macaca mulatta; Maternal Deprivation; Methylation; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Prefrontal Cortex; Promoter Regions, Genetic | 2014 |
Excision of 5-hydroxymethylcytosine by DEMETER family DNA glycosylases.
Topics: 5-Methylcytosine; Animals; Arabidopsis; Arabidopsis Proteins; Cytosine; DNA Glycosylases; DNA Methylation; Mice; N-Glycosyl Hydrolases; Nuclear Proteins; Signal Transduction; Trans-Activators | 2014 |
Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Cerebellum; Chromatin; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Histones; Humans; Male; Mixed Function Oxygenases; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Myocardium; Organ Specificity; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptors, Notch | 2014 |
Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cytosine; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Humans; Ivermectin; Male; Methylation | 2014 |
Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Base Sequence; Boronic Acids; Cells, Cultured; Cytosine; Embryonic Stem Cells; Introns; Mice; PAX5 Transcription Factor; Polymerase Chain Reaction; Sequence Analysis, DNA | 2014 |
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins | 2014 |
Genome-wide analysis of DNA 5-hmC in peripheral blood of uremia by hMeDIP-chip.
Topics: 5-Methylcytosine; Case-Control Studies; CpG Islands; Cytosine; DNA Methylation; Genome-Wide Association Study; Humans; Promoter Regions, Genetic; Uremia | 2014 |
High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma.
Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cytosine; DNA Methylation; Female; Hepatectomy; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome | 2014 |
TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.
Topics: 5-Methylcytosine; Adult; Case-Control Studies; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression; Humans; Leukocytes, Mononuclear; Male; Multiple Sclerosis; Promoter Regions, Genetic; Proto-Oncogene Proteins | 2014 |
A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine.
Topics: 5-Methylcytosine; Bacterial Proteins; Base Sequence; Cytosine; DNA; Escherichia coli; Gene Expression; Molecular Sequence Data; Mutation; Oligonucleotides; Recombinant Proteins; Substrate Specificity; Thymine; Uracil; Uracil-DNA Glycosidase | 2014 |
Re: paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels.
Topics: 5-Methylcytosine; Aging; Cytosine; DNA; DNA Methylation; Humans; Male; Paternal Age; Spermatozoa | 2014 |
Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation.
Topics: 5-Methylcytosine; Adaptation, Physiological; Animals; Behavior, Animal; Conditioning, Psychological; Cytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Extinction, Psychological; Fear; Genome-Wide Association Study; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neocortex; Neurons; Proto-Oncogene Proteins | 2014 |
Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samples.
Topics: 5-Methylcytosine; Aged; Arsenic; Cadmium; Cross-Sectional Studies; Cytosine; DNA; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Female; Humans; Longitudinal Studies; Male; Metals; Middle Aged | 2014 |
Effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Models, Molecular; Oxidation-Reduction | 2014 |
TET1 exerts its tumor suppressor function by interacting with p53-EZH2 pathway in gastric cancer.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cytosine; Dioxygenases; DNA-Activated Protein Kinase; DNA-Binding Proteins; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gastric Mucosa; Humans; Ki-67 Antigen; Mice; Mixed Function Oxygenases; Nuclear Proteins; Phosphorylation; Phosphoserine; Polycomb Repressive Complex 2; Protein Binding; Proto-Oncogene Proteins; Signal Transduction; Stomach Neoplasms; Tissue Array Analysis; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
PRIMA-1 selectively induces global DNA demethylation in p53 mutant-type thyroid cancer cells.
Topics: 5-Methylcytosine; Aza Compounds; bcl-2-Associated X Protein; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Mixed Function Oxygenases; Models, Biological; Mutation; Nuclear Proteins; Proto-Oncogene Proteins; Thyroid Neoplasms; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Programming and inheritance of parental DNA methylomes in mammals.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Development; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Promoter Regions, Genetic | 2014 |
Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2.
Topics: 5-Methylcytosine; Binding Sites; Crystallography, X-Ray; Cytosine; Humans; Hydrogen Bonding; Models, Molecular; Oligonucleotides; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Ubiquitin-Protein Ligases | 2014 |
Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Circular Dichroism; Cytosine; Dinucleoside Phosphates; E-Box Elements; Humans; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Multimerization | 2014 |
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Topics: 5-Methylcytosine; Cell Hypoxia; Cell Line, Tumor; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mixed Function Oxygenases; Neuroblastoma; Proto-Oncogene Proteins; Response Elements; Up-Regulation | 2014 |
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Carbon Isotopes; Chromatin Assembly and Disassembly; Chromatography, Liquid; Cytosine; Dioxygenases; DNA; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression; Mice; Molecular Sequence Data; Oxidation-Reduction; Pentoxyl; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Mass, Electrospray Ionization; Thymine; Transcription Factors | 2014 |
Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Damage; DNA Methylation; Hydroxyl Radical; Oxidation-Reduction; Thymine | 2014 |
Deamination features of 5-hydroxymethylcytosine, a radical and enzymatic DNA oxidation product.
Topics: 5-Methylcytosine; Computer Simulation; Cytosine; Deamination; DNA; Energy Transfer; Hydrolysis; Models, Chemical; Models, Molecular; Molecular Structure; Oxidation-Reduction; Quantum Theory; Structure-Activity Relationship; Water | 2014 |
TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Topics: 5-Methylcytosine; Catalytic Domain; Cell Differentiation; CpG Islands; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; HEK293 Cells; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; Transcription, Genetic | 2014 |
High levels of global DNA methylation are an independent adverse prognostic factor in a series of 90 patients with de novo myelodysplastic syndrome.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Bone Marrow; Cytosine; DNA; DNA Methylation; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Survival Analysis | 2014 |
CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4.
Topics: 5-Methylcytosine; Bacteriophage T4; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Associated Proteins; CRISPR-Cas Systems; Cytosine; DNA, Bacterial; Endonucleases; Escherichia coli; Streptococcus pyogenes | 2014 |
Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma.
Topics: 5-Methylcytosine; Age Factors; Brain Stem Neoplasms; Child; Child, Preschool; Cytosine; DNA Methylation; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Statistics, Nonparametric; Tissue Array Analysis | 2014 |
Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA.
Topics: 5-Methylcytosine; CCAAT-Enhancer-Binding Proteins; Cytosine; Dimerization; DNA; DNA Cleavage; DNA Restriction Enzymes; Endodeoxyribonucleases; Models, Molecular; Nuclear Proteins; Protein Structure, Tertiary; Ubiquitin-Protein Ligases | 2014 |
Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.
Topics: 5-Methylcytosine; Base Pairing; Cell Proliferation; Cytosine; DNA; DNA Mismatch Repair; DNA Replication; Epigenesis, Genetic; Guanine; Humans; Thymine DNA Glycosylase | 2014 |
Distinct global DNA methylation status in B-cell lymphomas: immunohistochemical study of 5-methylcytosine and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Humans; Immunohistochemistry; Lymphoma, B-Cell; Male; Middle Aged; Young Adult | 2014 |
Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.
Topics: 5-Methylcytosine; Cell Differentiation; Cell Line, Tumor; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sequence Analysis, DNA | 2014 |
Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial.
Topics: 5-Methylcytosine; Adolescent; Adult; Animals; Chlorocebus aethiops; Clinical Trials as Topic; COS Cells; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA-Binding Proteins; Female; Gene Expression Regulation, Leukemic; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Multicenter Studies as Topic; Mutation; Neoplasm Proteins; Prognosis; Prospective Studies; Proto-Oncogene Proteins; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transfection; Young Adult | 2014 |
Dynamics of genomic 5-hydroxymethylcytosine during mouse oocyte growth.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Female; Genome; Mice, Inbred C57BL; Oocytes; Proto-Oncogene Proteins; Zygote | 2014 |
5-Hydroxymethylcytosine promotes proliferation of human uterine leiomyoma: a biological link to a new epigenetic modification in benign tumors.
Topics: 5-Methylcytosine; Adult; Cell Proliferation; Cytosine; Epigenesis, Genetic; Female; Humans; Leiomyoma; Middle Aged; Uterine Neoplasms | 2014 |
Comparison of the absolute level of epigenetic marks 5-methylcytosine, 5-hydroxymethylcytosine, and 5-hydroxymethyluracil between human leukocytes and sperm.
Topics: 5-Methylcytosine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Leukocytes; Male; Pentoxyl; Poland; Spectrometry, Mass, Electrospray Ionization; Spermatozoa; Tandem Mass Spectrometry; Thymidine; Up-Regulation | 2014 |
Epigenetically modified nucleotides in chronic heroin and cocaine treated mice.
Topics: 5-Methylcytosine; Animals; Brain; Brain Chemistry; Cocaine; Cytosine; Dose-Response Relationship, Drug; Epigenesis, Genetic; Heroin; Liver; Male; Mice; Mice, Inbred C57BL | 2014 |
Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Lineage; Cytosine; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins; T-Lymphocyte Subsets; T-Lymphocytes | 2014 |
Spectroscopic quantification of 5-hydroxymethylcytosine in genomic DNA.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Methylation; DNA, Fungal; Equipment Design; Genomics; Limit of Detection; Mice; Molecular Sequence Data; Saccharomyces cerevisiae; Spectrometry, Fluorescence | 2014 |
Tet-mediated formation of 5-hydroxymethylcytosine in RNA.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; HEK293 Cells; Humans; Mice; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA | 2014 |
5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cytosine; Female; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Lymph Nodes; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Nevus; Sentinel Lymph Node Biopsy; Skin Neoplasms | 2015 |
Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.
Topics: 5-Methylcytosine; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Cytosine; DNA Methylation; DNA Repair; Gene Expression Regulation, Neoplastic; Genome, Human; HEK293 Cells; Humans; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; Thymine DNA Glycosylase | 2014 |
5-Hydroxymethylcytosine is a useful marker to differentiate between dermatofibrosarcoma protuberans and dermatofibroma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dermatofibrosarcoma; Humans; Skin Neoplasms | 2016 |
Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer.
Topics: 5-Methylcytosine; Aged; Chromatography, Liquid; Cytosine; Deoxycytidine; Dioxygenases; DNA-Binding Proteins; Enzymes; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mixed Function Oxygenases; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Stomach Neoplasms; Tandem Mass Spectrometry | 2015 |
Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase.
Topics: 5-Methylcytosine; Alternative Splicing; Amino Acid Sequence; Animals; Bees; Brain; Catalytic Domain; Cytosine; Dioxygenases; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; HEK293 Cells; Humans; Insect Proteins; Male; Molecular Sequence Data; Organ Specificity; Ovary; Sequence Alignment; Testis; Transgenes | 2014 |
5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation.
Topics: 5-Methylcytosine; Animals; Binding Sites; Cell Lineage; Cytosine; Embryonic Stem Cells; Enhancer Elements, Genetic; Epigenesis, Genetic; Histones; Mice; RNA, Messenger; Transcription Factors | 2014 |
Decrease of 5-hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid.
Topics: 5-Methylcytosine; Animals; Aristolochic Acids; Carcinogenesis; Carcinogens; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Liver; Mutation; Neoplasms; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Transgenic | 2015 |
Quantum chemical investigations on the nonradiative deactivation pathways of cytosine derivatives.
Topics: 5-Methylcytosine; Cytosine; Flucytosine; Photolysis; Quantum Theory; Stereoisomerism; Thermodynamics | 2014 |
Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells.
Topics: 5-Methylcytosine; Cell Differentiation; Cells, Cultured; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Molecular Sequence Data; Myoblasts, Cardiac; Neural Stem Cells; Pluripotent Stem Cells; Sequence Analysis, DNA | 2014 |
5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels.
Topics: 5-Methylcytosine; Animals; Brain; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Embryonic Stem Cells; Enzyme Inhibitors; Gene Expression Regulation; Gene Knockout Techniques; Genomic Imprinting; Germ Cells; Humans; Mice; Neurons; NIH 3T3 Cells; Sequence Analysis, DNA; Transcription, Genetic | 2014 |
Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cytosine; DNA Methylation; Entorhinal Cortex; Epigenesis, Genetic; Female; Humans; Male; Middle Aged | 2015 |
Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus.
Topics: 5-Methylcytosine; Aging; Animals; Cytosine; DNA Methylation; Gene Expression Regulation; Gene-Environment Interaction; Hippocampus; Learning; Mice | 2014 |
Hydroxymethylated cytosines are associated with elevated C to G transversion rates.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; Humans; Mice; Mutation | 2014 |
JBP1-seq: a fast and efficient method for genome-wide profiling of 5hmC.
Topics: 5-Methylcytosine; Brain; Cytosine; DNA Methylation; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Magnetic Phenomena; Protein-Arginine N-Methyltransferases; Recombinant Proteins; Sequence Analysis, DNA | 2014 |
RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Gene Library; High-Throughput Nucleotide Sequencing; Humans; Liver Neoplasms; Molecular Sequence Annotation; Sequence Analysis, DNA | 2014 |
[Simultaneous analysis of global DNA methylation and hydroxymethylation in tissues by liquid chromatography-tandem mass spectrometry].
Topics: 5-Methylcytosine; Animals; Chromatography, Liquid; Cytidine; Cytosine; Deoxyguanosine; DNA; DNA Methylation; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Exposure to arsenic via drinking water induces 5-hydroxymethylcytosine alteration in rat.
Topics: 5-Methylcytosine; Animals; Arsenic; Cytosine; DNA Methylation; Drinking Water; Epigenesis, Genetic; Gene Expression Regulation; Male; Rats; Rats, Sprague-Dawley; Water Pollutants, Chemical | 2014 |
5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Differentiation; Cell Line; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Mice; Mice, Knockout; Oxidation-Reduction; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sequence Analysis, DNA; Transcriptome; Zinc Fingers | 2014 |
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Topics: 5-Methylcytosine; Acetylation; Brain Neoplasms; Carcinogenesis; Chromatin; Cytosine; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Histones; Humans; Methylation; Mixed Function Oxygenases; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins; Repressor Proteins; Transcription Factors; Transcription, Genetic | 2014 |
Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum.
Topics: 5-Methylcytosine; Adolescent; Autistic Disorder; Cerebellum; Cytosine; Female; Gene Expression; Homeodomain Proteins; Humans; Male; Methyl-CpG-Binding Protein 2; Nerve Tissue Proteins; Promoter Regions, Genetic | 2014 |
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion.
Topics: 5-Methylcytosine; Animals; Autophagy-Related Proteins; Calcium-Binding Proteins; Cerebrovascular Disorders; Chronic Disease; Corpus Callosum; Cytosine; Dioxygenases; Disease Models, Animal; DNA-Binding Proteins; Gray Matter; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred C57BL; Microfilament Proteins; Neural Stem Cells; Neuroglia; Oxidative Stress; Pilot Projects; Proto-Oncogene Proteins; Random Allocation; White Matter | 2014 |
A B-cell targeting virus disrupts potentially protective genomic methylation patterns in lymphoid tissue by increasing global 5-hydroxymethylcytosine levels.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Birnaviridae Infections; Bursa of Fabricius; Chickens; Cytosine; DNA Methylation; Genome; Infectious bursal disease virus; Poultry Diseases | 2014 |
Loss of expression of 5-hydroxymethylcytosine in CD30-positive cutaneous lymphoproliferative disorders.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Child; Cytosine; Epigenesis, Genetic; Female; Humans; Immunohistochemistry; Ki-1 Antigen; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphomatoid Papulosis; Male; Middle Aged; Retrospective Studies; Skin Neoplasms; Young Adult | 2014 |
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.
Topics: 5-Methylcytosine; Animals; Catalytic Domain; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Cleavage; Endodeoxyribonucleases; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Recombination, Genetic; Tumor Suppressor p53-Binding Protein 1 | 2014 |
Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing.
Topics: 5-Methylcytosine; Animals; Base Sequence; Chromatin; Cytosine; DNA Methylation; DNA Repair; Embryonic Stem Cells; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Methyltransferases; Mice; Thymine DNA Glycosylase | 2014 |
HTS for SMFS, organohalide respiration, new epigenetic mark, and a decoy receptor.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Epigenomics; High-Throughput Screening Assays; Hydrocarbons, Halogenated; Hydrolases; Microfluidic Analytical Techniques; Oligonucleotide Array Sequence Analysis; Tumor Necrosis Factor Decoy Receptors | 2014 |
5-hydroxymethylcytosine is not present in appreciable quantities in Arabidopsis DNA.
Topics: 5-Methylcytosine; Arabidopsis; Chromatography, Thin Layer; Cytosine; DNA, Plant; Enzyme-Linked Immunosorbent Assay; Immunoprecipitation; Mass Spectrometry; Real-Time Polymerase Chain Reaction | 2014 |
DNA modifications: Another stable base in DNA.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Humans | 2014 |
5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Topics: 5-Methylcytosine; Animals; Cell Cycle; Cell Proliferation; Cytosine; DNA; DNA Methylation; HCT116 Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred C57BL | 2014 |
Single base resolution analysis of 5-methylcytosine and 5-hydroxymethylcytosine by RRBS and TAB-RRBS.
Topics: 5-Methylcytosine; Cytosine; Deoxyribonuclease HpaII; Glycosylation; Humans; Oxidation-Reduction; Sequence Analysis, DNA; Sulfites | 2015 |
Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay.
Topics: 5-Methylcytosine; Cytosine; DNA; Epigenesis, Genetic; Humans; Immunoenzyme Techniques; Limit of Detection; Neoplasms | 2014 |
Genomics special issue on 5-hydroxymethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans | 2014 |
Label free detection of 5'hydroxymethylcytosine within CpG islands using optical sensors.
Topics: 5-Methylcytosine; Animals; Antibodies, Immobilized; Biosensing Techniques; CpG Islands; Cytosine; DNA Methylation; Optics and Photonics | 2015 |
5-Hydroxymethylcytosine, the "Sixth Base", during brain development and ageing.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Animals; Animals, Newborn; Brain; Cytosine; Female; Fetus; Gestational Age; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Phosphopyruvate Hydratase; Young Adult | 2015 |
Role of 5-hydroxymethylcytosine level in diagnosis and prognosis prediction of intrahepatic cholangiocarcinoma.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cytosine; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis | 2015 |
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Mice, Knockout; Mutation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Sequence Analysis, DNA; WT1 Proteins | 2014 |
Chemical display of pyrimidine bases flipped out by modification-dependent restriction endonucleases of MspJI and PvuRts1I families.
Topics: 5-Methylcytosine; Bacterial Proteins; Catalytic Domain; Cytosine; DNA Restriction Enzymes; DNA, Bacterial; Models, Molecular; Protein Binding | 2014 |
Chromosome hydroxymethylation patterns in human zygotes and cleavage-stage embryos.
Topics: 5-Methylcytosine; Blastocyst; Cytosine; DNA Methylation; Female; Genome, Human; Humans; Zygote | 2015 |
Integrated analyses of DNA methylation and hydroxymethylation reveal tumor suppressive roles of ECM1, ATF5, and EOMES in human hepatocellular carcinoma.
Topics: 5-Methylcytosine; Activating Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Comparative Genomic Hybridization; Cytosine; DNA Methylation; Epigenesis, Genetic; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Molecular Sequence Data; Promoter Regions, Genetic; Sequence Analysis, DNA; T-Box Domain Proteins | 2014 |
DNA cytosine methylation and hydroxymethylation at the borders.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Promoter Regions, Genetic | 2014 |
Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy.
Topics: 5-Methylcytosine; Animals; CD4-Positive T-Lymphocytes; Culture Media; Cytosine; DNA Methylation; Epigenesis, Genetic; Immunotherapy; Mice; Mice, Inbred C57BL; Peptides; Programmed Cell Death 1 Receptor; Promoter Regions, Genetic | 2014 |
Detection of human urinary 5-hydroxymethylcytosine by stable isotope dilution HPLC-MS/MS analysis.
Topics: 5-Methylcytosine; Adult; Bicarbonates; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; Female; Humans; Indicator Dilution Techniques; Isotopes; Male; Solid Phase Extraction; Tandem Mass Spectrometry; Young Adult | 2015 |
Programmable sensors of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Cytosine; DNA; Epigenesis, Genetic; Genetic Engineering; Models, Molecular; Molecular Structure; Tandem Repeat Sequences; Trans-Activators | 2015 |
Base-pairing energies of protonated nucleobase pairs and proton affinities of 1-methylated cytosines: model systems for the effects of the sugar moiety on the stability of DNA i-motif conformations.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; DNA; DNA Methylation; Models, Molecular; Nucleic Acid Conformation; Protons; Thermodynamics | 2015 |
Induction of chronic oxidative stress, chronic inflammation and aberrant patterns of DNA methylation in the liver of titanium-exposed CBA/CaJ mice.
Topics: 5-Methylcytosine; Animals; Chromosomal Instability; Cytosine; DNA Methylation; Dose-Response Relationship, Radiation; Epigenesis, Genetic; Hematopoietic Stem Cells; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred CBA; NF-kappa B; Oxidative Stress; Time Factors; Titanium; Tumor Necrosis Factor-alpha | 2015 |
Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cells, Cultured; Cytosine; Ethanol; Methyl-CpG-Binding Protein 2; Mice; Neural Stem Cells; Regulatory Elements, Transcriptional | 2015 |
Understanding the structural and dynamic consequences of DNA epigenetic modifications: computational insights into cytosine methylation and hydroxymethylation.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Models, Molecular; Molecular Dynamics Simulation; Nucleic Acid Conformation; Protein Binding | 2014 |
Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
Topics: 5-Methylcytosine; Cytosine; DNA; Oligonucleotides; Thymine DNA Glycosylase | 2015 |
A sensitive approach to map genome-wide 5-hydroxymethylcytosine and 5-formylcytosine at single-base resolution.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA Restriction Enzymes; Embryonic Stem Cells; Epigenesis, Genetic; Gene Library; Histones; Mice; Restriction Mapping | 2015 |
Spatial distribution of 5-hydroxymethyl cytosine in rat brain and temporal distribution in striatum.
Topics: 5-Methylcytosine; Animals; Brain; Corpus Striatum; Cytosine; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2015 |
Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems.
Topics: 5-Methylcytosine; Adaptation, Biological; Animals; Cell Culture Techniques; Cells, Cultured; Cellular Reprogramming; Cytosine; Dioxygenases; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Genetic Loci; Mammals; Mice, Inbred C57BL; Transcriptome | 2015 |
Analysis of nanopore data using hidden Markov models.
Topics: 5-Methylcytosine; Algorithms; Cytosine; DNA Methylation; Epigenomics; High-Throughput Nucleotide Sequencing; Humans; Markov Chains; Nanopores; Sequence Alignment; Sequence Analysis, DNA | 2015 |
The Tet1 and histone methylation expression pattern in dairy goat testis.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; Dairying; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Fluorescent Antibody Technique; Gene Expression; Goats; Histones; Male; Methylation; Spermatogenesis; Spermatogonia; Testis | 2015 |
Formation and abundance of 5-hydroxymethylcytosine in RNA.
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; Mice; Mice, Inbred C57BL; Molecular Structure; Oxidation-Reduction; RNA; Tandem Mass Spectrometry | 2015 |
The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; Cytosine; Deoxyguanosine; DNA Methylation; Fatty Liver; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Mice, Inbred C57BL; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced γH2AX accumulation.
Topics: 5-Methylcytosine; Animals; Cell Division; Cell Line; Cells, Cultured; Chromosomal Instability; Chromosomal Proteins, Non-Histone; Chromosome Aberrations; Chromosome Segregation; Cytosine; Dioxygenases; DNA Methylation; DNA Replication; DNA-Binding Proteins; Embryo, Mammalian; Epigenesis, Genetic; Female; Gene Knockout Techniques; Histones; Male; Mice; Protein Transport; Proto-Oncogene Proteins; Repressor Proteins; Zygote | 2015 |
5-Hydroxymethylcytosine and 5-formylcytosine containing deoxyoligonucleotides: facile syntheses and melting temperature studies.
Topics: 5-Methylcytosine; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Copper; Cytosine; Oligonucleotides; Oxidation-Reduction; Transition Temperature | 2015 |
Accurate measurement of 5-methylcytosine and 5-hydroxymethylcytosine in human cerebellum DNA by oxidative bisulfite on an array (OxBS-array).
Topics: 5-Methylcytosine; Adult; Cerebellum; Cytosine; DNA; DNA Methylation; Humans; Male; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Reproducibility of Results; Sulfites | 2015 |
Impaired active DNA demethylation in zygotes generated by round spermatid injection.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chorionic Gonadotropin; Cytosine; DNA Methylation; Embryo Transfer; Female; Germ Cells; Histones; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Microscopy, Fluorescence; Oocytes; Pregnancy; Pregnancy, Animal; Sperm Injections, Intracytoplasmic; Spermatids; Zygote | 2015 |
Neighboring Genes Show Correlated Evolution in Gene Expression.
Topics: 5-Methylcytosine; Animals; Cerebellum; Chromosomes, Human, Pair 2; Computer Simulation; Cytosine; Evolution, Molecular; Female; Gene Expression Regulation; Genes; Histones; Humans; Lysine; Male; Methylation; Monte Carlo Method; Organ Specificity; Primates; Statistics, Nonparametric; Up-Regulation | 2015 |
Hippocampal increase of 5-hmC in the glucocorticoid receptor gene following acute stress.
Topics: 3' Untranslated Regions; 5-Methylcytosine; Acute Disease; Animals; Cytosine; Disease Models, Animal; Hippocampus; Mice; Neurons; Random Allocation; Receptors, Glucocorticoid; Restraint, Physical; Stress, Psychological | 2015 |
Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia.
Topics: 5-Methylcytosine; Case-Control Studies; Cell Shape; Cytosine; DNA; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomic Imprinting; Humans; Infertility, Male; Male; Phenotype; Sperm Motility; Spermatogenesis; Spermatozoa | 2015 |
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action.
Topics: 5-Methylcytosine; Animals; Behavior, Animal; Cocaine; Cytosine; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Gene Expression; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Proto-Oncogene Proteins | 2015 |
C/EBPβ (CEBPB) protein binding to the C/EBP|CRE DNA 8-mer TTGC|GTCA is inhibited by 5hmC and enhanced by 5mC, 5fC, and 5caC in the CG dinucleotide.
Topics: 5-Methylcytosine; Animals; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Crystallography, X-Ray; Cytosine; Cytosine Nucleotides; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Nucleotide Motifs; Transcription Factors | 2015 |
Cocaine shapes chromatin landscapes via Tet1.
Topics: 5-Methylcytosine; Animals; Cocaine; Cytosine; DNA-Binding Proteins; Gene Expression; Male; Nucleus Accumbens; Proto-Oncogene Proteins | 2015 |
Post-conversion targeted capture of modified cytosines in mammalian and plant genomes.
Topics: 5-Methylcytosine; Alleles; Animals; Cell Line; Cytosine; DNA Methylation; Genome, Plant; Genomics; High-Throughput Nucleotide Sequencing; Humans; Mice; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Sulfites | 2015 |
Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip.
Topics: 5-Methylcytosine; Case-Control Studies; Chromosome Mapping; Computational Biology; CpG Islands; Cytosine; DNA Methylation; Gene Expression Profiling; Gene Ontology; Genome-Wide Association Study; Humans; Lupus Erythematosus, Systemic; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Signal Transduction | 2015 |
Prognostic values of 5-hmC, 5-mC and TET2 in epithelial ovarian cancer.
Topics: 5-Methylcytosine; Adult; Aged; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Case-Control Studies; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Lymphatic Metastasis; Middle Aged; Neoplasm Grading; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Prognosis; Proto-Oncogene Proteins; Survival Analysis | 2015 |
Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine.
Topics: 5-Methylcytosine; Algorithms; Animals; Cytosine; DNA; DNA-Binding Proteins; Epigenesis, Genetic; Epigenomics; Humans; Mice; Mixed Function Oxygenases; Mutation; Naegleria; Oxygen; Oxygenases; Phylogeny; Proto-Oncogene Proteins; Protozoan Proteins; Sequence Analysis, DNA; Thymidine | 2015 |
TET3 is recruited by REST for context-specific hydroxymethylation and induction of gene expression.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Mice; Neurons; Proto-Oncogene Proteins; Repressor Proteins; Retina; Transcriptional Activation | 2015 |
5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer.
Topics: 5-Methylcytosine; Cell Proliferation; Colonic Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Proto-Oncogene Proteins | 2015 |
The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytokines; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; E1A-Associated p300 Protein; Epigenesis, Genetic; Gene Expression Regulation; Genome; Humans; Mice; Mice, Transgenic; Proto-Oncogene Proteins; STAT4 Transcription Factor; T-Box Domain Proteins; Th1 Cells; Th17 Cells | 2015 |
TET1 is a tumor suppressor of hematopoietic malignancy.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Cell Differentiation; Cell Lineage; Chromosomal Instability; Cytosine; DNA Methylation; DNA Repair; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Exome; Gene Expression Profiling; Humans; Lymphoma, B-Cell; Mice; Mutation; Proto-Oncogene Proteins; Tumor Suppressor Proteins | 2015 |
Regulation of telomeric i-motif stability by 5-methylcytosine and 5-hydroxymethylcytosine modification.
Topics: 5-Methylcytosine; Circular Dichroism; Cytosine; DNA; DNA Methylation; Humans; Nucleotide Motifs; Protein Structure, Tertiary; Telomere; Temperature | 2015 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2015 |
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Acetylation; Animals; Cell Differentiation; Cell Lineage; Cells, Cultured; Chromatin Assembly and Disassembly; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Genotype; Histones; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Nanog Homeobox Protein; Neurogenesis; Octamer Transcription Factor-3; Phenotype; Proto-Oncogene Proteins; RNA Interference; Signal Transduction; Sirtuins; SOXB1 Transcription Factors; Teratoma; Transfection | 2015 |
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine | 2015 |
Effects of particulate matter exposure on blood 5-hydroxymethylation: results from the Beijing truck driver air pollution study.
Topics: 5-Methylcytosine; Adolescent; Adult; Air Pollution; Beijing; Cytosine; Environmental Exposure; Female; Humans; Male; Middle Aged; Particulate Matter; Young Adult | 2015 |
Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging.
Topics: 5-Methylcytosine; Aging; Animals; Cellular Senescence; Cyclohexenes; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Histones; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Oocytes; Ovary; Protein Isoforms; Proto-Oncogene Proteins; Thymine DNA Glycosylase; Vinyl Compounds | 2015 |
Direct conjugation of peptides and 5-hydroxymethylcytosine in DNA.
Topics: 5-Methylcytosine; Amino Acid Sequence; Cytosine; DNA; DNA-Cytosine Methylases; Models, Molecular; Peptides; Spiroplasma | 2015 |
Oxygen concentration controls epigenetic effects in models of familial paraganglioma.
Topics: 5-Methylcytosine; Animals; Case-Control Studies; Cytosine; Dioxygenases; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Gene Knockdown Techniques; HEK293 Cells; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Mice, Inbred C57BL; Models, Biological; Oxygen; Paraganglioma; Succinate Dehydrogenase; Succinic Acid | 2015 |
Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; DNA-Binding Proteins; Models, Molecular; Protein Binding; Protein Engineering; Protein Structure, Tertiary | 2015 |
Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Epigenesis, Genetic; Female; Glioblastoma; Histones; Humans; Isocitrate Dehydrogenase; Ki-67 Antigen; Loss of Heterozygosity; Male; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2015 |
Tuning the pH Response of i-Motif DNA Oligonucleotides.
Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA, Single-Stranded; Humans; Hydrogen-Ion Concentration; Kinetics; Nucleotide Motifs; Oligodeoxyribonucleotides; Telomere; Temperature | 2015 |
Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood.
Topics: 5-Methylcytosine; Cell Line; CpG Islands; Cytosine; DNA Methylation; Environmental Exposure; Fetal Blood; Human Embryonic Stem Cells; Humans; Lead; Mexico; Sequence Analysis, DNA; Sex Factors; Umbilical Cord | 2015 |
Cell Fate by SIRT6 and TETs.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; Sirtuins; Transcription Factors | 2015 |
Placental 5-methylcytosine and 5-hydroxymethylcytosine patterns associate with size at birth.
Topics: 5-Methylcytosine; Birth Weight; Cyclin-Dependent Kinase Inhibitor p57; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Placenta; Pregnancy | 2015 |
TET family proteins and 5-hydroxymethylcytosine in esophageal squamous cell carcinoma.
Topics: 5-Methylcytosine; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Cell Survival; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Immunohistochemistry; Intestinal Mucosa; Kaplan-Meier Estimate; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prognosis; Proto-Oncogene Proteins; RNA, Messenger; Sequence Analysis, DNA | 2015 |
5-Formylcytosine can be a stable DNA modification in mammals.
Topics: 5-Methylcytosine; Aging; Animals; Animals, Newborn; Brain; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation, Developmental; Half-Life; Liver; Mice; Mice, Inbred C57BL; Myocardium | 2015 |
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; DNA Methylation; DNA Repair; Epigenesis, Genetic; Hydrogen Bonding; Kinetics; RNA Polymerase II; Saccharomyces cerevisiae; Substrate Specificity; Templates, Genetic; Thymine DNA Glycosylase; Transcription Elongation, Genetic | 2015 |
MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cells, Cultured; Cytosine; Dioxygenases; DNA-Binding Proteins; Ectoderm; Embryoid Bodies; Endoderm; Epigenesis, Genetic; HEK293 Cells; Humans; Left-Right Determination Factors; Mesoderm; Mice; MicroRNAs; Mouse Embryonic Stem Cells; Proto-Oncogene Proteins; Thymine DNA Glycosylase | 2015 |
5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme.
Topics: 5-Methylcytosine; Amino Acid Sequence; Catalytic Domain; Cytosine; DNA Damage; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glutathione Transferase; HEK293 Cells; Humans; Immunoprecipitation; Mixed Function Oxygenases; Molecular Sequence Data; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Recombinant Proteins; Sequence Homology, Amino Acid | 2015 |
Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.
Topics: 5-Methylcytosine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Animals; Brain; Child; Child, Preschool; Cytosine; Humans; Infant; Mice; Middle Aged; Young Adult | 2015 |
A Cell Electrofusion Chip for Somatic Cells Reprogramming.
Topics: 5-Methylcytosine; Animals; Cellular Reprogramming; Cytosine; DNA; DNA Methylation; Electroporation; Homeodomain Proteins; Karyotyping; Mice; Mice, Nude; Microfluidic Analytical Techniques; Mouse Embryonic Stem Cells; Nanog Homeobox Protein; NIH 3T3 Cells; Octamer Transcription Factor-3; Real-Time Polymerase Chain Reaction | 2015 |
Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA-Binding Proteins; DNA, Bacterial; Firmicutes; Genome, Bacterial; Mice; Nucleotide Motifs; Proto-Oncogene Proteins; Sequence Analysis, DNA; Sulfites | 2015 |
Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Gene Knockdown Techniques; HEK293 Cells; Humans; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Up-Regulation | 2015 |
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer.
Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine | 2015 |
The dynamics of DNA methylation and hydroxymethylation during amelogenesis.
Topics: 5-Methylcytosine; Amelogenesis; Animals; Cytosine; DNA Methylation; Incisor; Mandible; Mice; Mice, Inbred ICR | 2015 |
Genome-Wide Mapping of 5mC and 5hmC Identified Differentially Modified Genomic Regions in Late-Onset Severe Preeclampsia: A Pilot Study.
Topics: 5-Methylcytosine; Adult; Cytosine; DNA Methylation; Epigenesis, Genetic; ErbB Receptors; Female; Genome-Wide Association Study; Genome, Human; Humans; Pilot Projects; Pre-Eclampsia; Pregnancy; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Signal Transduction | 2015 |
Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury.
Topics: 5-Methylcytosine; Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Male; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reperfusion Injury | 2015 |
Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations.
Topics: 5-Methylcytosine; Cytosine; Diagnosis, Differential; Humans; Immunohistochemistry; Lymph Nodes; Lymphatic Metastasis; Melanocytes; Melanoma; Nevus, Pigmented; Skin Neoplasms; Tissue Array Analysis | 2015 |
Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype.
Topics: 5-Methylcytosine; Adult; Aged; Breast Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression; Humans; Immunohistochemistry; Middle Aged; Mixed Function Oxygenases; Neoplasm Grading; Neoplasm Staging; Prognosis; Protein Transport; Proto-Oncogene Proteins; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Survival Analysis; Young Adult | 2015 |
Experimental Approaches for Target Profiling of RNA Cytosine Methyltransferases.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Humans; RNA Processing, Post-Transcriptional; Sequence Analysis, RNA; tRNA Methyltransferases | 2015 |
Increased DNA methylation in the livers of patients with alcoholic hepatitis.
Topics: 5-Methylcytosine; Biomarkers; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Hepatitis, Alcoholic; Hepatocytes; Humans; Immunoenzyme Techniques; Liver | 2015 |
Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes.
Topics: 5-Methylcytosine; Chromatography, Liquid; Chromosome Mapping; Cytosine; DNA Transposable Elements; DNA, Plant; Epigenesis, Genetic; High-Throughput Nucleotide Sequencing; Oryza; Sequence Analysis, DNA; Tandem Mass Spectrometry | 2015 |
TET2 expression level and 5-hydroxymethylcytosine are decreased in refractory cytopenia of childhood.
Topics: 5-Methylcytosine; Adolescent; Case-Control Studies; Child; Child, Preschool; Cytosine; Dioxygenases; DNA Mutational Analysis; DNA-Binding Proteins; Female; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Humans; Infant; Male; MicroRNAs; Mutation; Myelodysplastic Syndromes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Transcriptome | 2015 |
Characterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine.
Topics: 5-Methylcytosine; Amino Acid Sequence; Catalytic Domain; Cytidine Deaminase; Cytosine; Humans; Methionine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Multimerization; Proteins | 2015 |
A novel electrochemical immunosensor for the quantitative detection of 5-hydroxymethylcytosine in genomic DNA of breast cancer tissue.
Topics: 5-Methylcytosine; Biosensing Techniques; Breast Neoplasms; Cytosine; DNA, Neoplasm; Female; Humans | 2015 |
Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.
Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Mixed Function Oxygenases; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Retrospective Studies; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Epigenetic regulation of human adipose-derived stem cells differentiation.
Topics: 5-Methylcytosine; Adipose Tissue; Adult Stem Cells; Cell Differentiation; Cell Line; Cell Lineage; Cytosine; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Developmental; Homeodomain Proteins; Humans; Mixed Function Oxygenases; Nanog Homeobox Protein; Octamer Transcription Factor-3; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteogenesis; Phenotype; Pluripotent Stem Cells; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; SOXB1 Transcription Factors | 2015 |
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Topics: 5-Methylcytosine; Amino Acid Substitution; Catalytic Domain; Cytosine; Dioxygenases; DNA; Models, Molecular; Naegleria; Thymine | 2015 |
Charting oxidized methylcytosines at base resolution.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mammals; Oxidation-Reduction | 2015 |
Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution.
Topics: 5-Methylcytosine; Adult; Base Pairing; Binding Sites; Chromosomes, Human; Cluster Analysis; Cytosine; Epigenesis, Genetic; Exons; Female; Gene Ontology; Genome, Human; Humans; Introns; Male; Prefrontal Cortex; Protein Processing, Post-Translational; Sequence Analysis, DNA; Sex Characteristics; X Chromosome Inactivation | 2015 |
Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
Topics: 5-Methylcytosine; Animals; Cell Line; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Epigenomics; Gene Expression Regulation; Genome; Mice; Mice, Transgenic; Oligonucleotides; Oxygen; Polymerase Chain Reaction; Sequence Analysis, DNA; Stem Cells; Sulfites | 2015 |
A Strategy for Accurate Quantification of 5-Methylcytosine and 5-Hydroxymethylcytosine at CpG Sites Within Gene Promoter.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; DNA Methylation; Female; Humans; Oxidation-Reduction; Promoter Regions, Genetic; Reproducibility of Results; Sequence Analysis, DNA; Tumor Cells, Cultured | 2015 |
Arsenite Targets the Zinc Finger Domains of Tet Proteins and Inhibits Tet-Mediated Oxidation of 5-Methylcytosine.
Topics: 5-Methylcytosine; Animals; Arsenites; Chromatography, Liquid; Cytosine; DNA; DNA-Binding Proteins; HEK293 Cells; Humans; Hydroxylation; Mice; Mouse Embryonic Stem Cells; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Zinc Fingers | 2015 |
Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins.
Topics: 5-Methylcytosine; Adult; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Heat-Shock Proteins; Humans; Liver; Male; Middle Aged; Mitochondria, Liver; Mixed Function Oxygenases; Non-alcoholic Fatty Liver Disease; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Proto-Oncogene Proteins; Transcription Factors | 2015 |
Stable 5-Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation.
Topics: 5-Methylcytosine; Animals; Cartilage; Cell Differentiation; Chondrocytes; Chondrogenesis; Cytosine; DNA-Binding Proteins; DNA, Intergenic; Embryonic Development; Extremities; Gene Expression Regulation, Developmental; Mice; Proto-Oncogene Proteins; Stem Cells; Transcriptional Activation | 2016 |
Sex-specific associations of arsenic exposure with global DNA methylation and hydroxymethylation in leukocytes: results from two studies in Bangladesh.
Topics: 5-Methylcytosine; Adult; Aged; Arsenic; Bangladesh; Cytosine; DNA Methylation; Drinking Water; Environmental Exposure; Female; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Sex Factors; Young Adult | 2015 |
Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
Topics: 5-Methylcytosine; Bacterial Infections; CpG Islands; Cytosine; Dendritic Cells; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Mycobacterium tuberculosis; Transcription Factors; Tuberculosis | 2015 |
Diagnosis of abnormal human fertilization status based on pronuclear origin and/or centrosome number.
Topics: 5-Methylcytosine; Aneuploidy; Case-Control Studies; Cell Nucleus; Centrosome; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Fertilization in Vitro; Fluorescent Antibody Technique; Genetic Techniques; Humans; Male; Sperm Injections, Intracytoplasmic; Spermatozoa; Zygote | 2015 |
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cytosine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hepatocyte Nuclear Factor 3-alpha; Humans; Hydroxylation; Immunohistochemistry; Male; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Neoplasm Transplantation; Prostatic Neoplasms; Proto-Oncogene Proteins; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, RNA; TOR Serine-Threonine Kinases | 2015 |
Water-bridged hydrogen bond formation between 5-hydroxylmethylcytosine (5-hmC) and its 3'-neighbouring bases in A- and B-form DNA duplexes.
Topics: 5-Methylcytosine; Base Pairing; Crystallography, X-Ray; Cytosine; DNA, A-Form; DNA, B-Form; Hydrogen Bonding; Molecular Dynamics Simulation; Water | 2015 |
DNA 5-hydroxymethylation in human adipose tissue differs between subcutaneous and visceral adipose tissue depots.
Topics: 5-Methylcytosine; Adipocytes; Adiposity; Aged; Biomarkers; Cell Size; Cytosine; DNA Methylation; Female; Humans; Intra-Abdominal Fat; Male; Middle Aged; Sex Factors; Subcutaneous Fat; Tomography, X-Ray Computed | 2015 |
Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism.
Topics: 5-Methylcytosine; Animals; Autistic Disorder; Corpus Striatum; Cytosine; Disease Models, Animal; DNA; DNA Methylation; Epigenesis, Genetic; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Annotation; Nerve Tissue Proteins; Reelin Protein | 2015 |
DNA methylation and demethylation dynamics.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA Repair; Humans | 2015 |
Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Small Cell; Cytosine; Epigenomics; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Male; Melanoma; Melanoma, Cutaneous Malignant; Middle Aged; Neoplasm Staging; Nevus, Pigmented; Prognosis; Skin Neoplasms; Young Adult | 2015 |
Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore.
Topics: 3' Untranslated Regions; 5-Methylcytosine; Chromatin Immunoprecipitation; CpG Islands; Cytosine; DNA Methylation; Female; Gene Silencing; Histone Code; Humans; Immunoenzyme Techniques; Male; Middle Aged; Mixed Function Oxygenases; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2015 |
Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.
Topics: 5-Methylcytosine; Adrenal Gland Neoplasms; Cell Nucleus; Cytosine; Fumarate Hydratase; Gene Silencing; HEK293 Cells; Histone-Lysine N-Methyltransferase; Humans; Immunohistochemistry; Mixed Function Oxygenases; Paraganglioma; Pheochromocytoma; Proto-Oncogene Proteins; Smooth Muscle Tumor; Succinate Dehydrogenase | 2015 |
Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Aging; Animals; Caloric Restriction; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression; Immunohistochemistry; Mice, Inbred C57BL; Purkinje Cells; Superoxide Dismutase; Superoxide Dismutase-1 | 2015 |
Profiling of methylation and demethylation pathways during brain development and ageing.
Topics: 5-Methylcytosine; Aging; Animals; Brain; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Transcriptome | 2016 |
Methylated Cytosines Mutate to Transcription Factor Binding Sites that Drive Tetrapod Evolution.
Topics: 5-Methylcytosine; Animals; Binding Sites; Biological Evolution; Cytosine; Dinucleoside Phosphates; DNA Methylation; Humans; Mice; Oligonucleotide Array Sequence Analysis; Protein Binding; Transcription Factors | 2015 |
Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency.
Topics: 5-Methylcytosine; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Behavior, Animal; Cells, Cultured; Cerebellum; Cytosine; DNA Damage; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Mice; Mice, Knockout; Proto-Oncogene Proteins; Purkinje Cells | 2015 |
Structural insight into substrate preference for TET-mediated oxidation.
Topics: 5-Methylcytosine; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Humans; Hydrogen Bonding; Mixed Function Oxygenases; Models, Molecular; Oxidation-Reduction; Protein Binding; Proto-Oncogene Proteins; Substrate Specificity | 2015 |
MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.
Topics: 5-Methylcytosine; Alternative Splicing; Animals; Cell Line, Tumor; Cytosine; Epigenesis, Genetic; Gene Amplification; Humans; Methyl-CpG-Binding Protein 2; Mice; Neoplasm Transplantation; Neoplasms; Protein Isoforms; ras Proteins; Signal Transduction | 2016 |
The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Mammals; Mass Spectrometry; Oxidation-Reduction; RNA | 2016 |
Single Site Discrimination of Cytosine, 5-Methylcytosine, and 5-Hydroxymethylcytosine in Target DNA Using Anthracene-Tagged Fluorescent Probes.
Topics: 5-Methylcytosine; Anthracenes; Cytosine; DNA; Fluorescent Dyes; Nucleic Acid Conformation | 2016 |
Selective oxidation of 5-hydroxymethylcytosine with micelle incarcerated oxidants to determine it at single base resolution.
Topics: 5-Methylcytosine; Base Sequence; Catalysis; Cytosine; Mass Spectrometry; Micelles; Oxidation-Reduction; Sulfites | 2015 |
Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Stress, Psychological | 2016 |
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
Topics: 5-Methylcytosine; Adenocarcinoma; Binding Sites; Cell Differentiation; Cell Line, Tumor; Colon; Colonic Neoplasms; Cytosine; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; Transcription Factors | 2015 |
Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression; Kidney; Liver; Lung; Male; Myocardium; Organ Specificity; Pentoxyl; Rats; Rats, Wistar; Swine; Tandem Mass Spectrometry; Thymus Gland | 2015 |
Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer.
Topics: 5-Methylcytosine; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Cytosine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Isocitrate Dehydrogenase; Kidney; Kidney Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude | 2016 |
Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution.
Topics: 5-Methylcytosine; Adolescent; Air Pollution; Alleles; Asthma; Case-Control Studies; Child; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Epithelial Cells; Female; Gene Expression; Humans; Male; Mixed Function Oxygenases; Nasal Mucosa; Promoter Regions, Genetic; Proto-Oncogene Proteins; Risk Factors; RNA, Messenger; Vehicle Emissions | 2016 |
Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.
Topics: 5-Methylcytosine; Allergens; Animals; Cytosine; Dinitrochlorobenzene; DNA Fragmentation; DNA Methylation; Epigenesis, Genetic; Female; Immunoprecipitation; Local Lymph Node Assay; Lymph Nodes; Mice, Inbred BALB C; Phthalic Anhydrides; Polymerase Chain Reaction; Promoter Regions, Genetic | 2016 |
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells.
Topics: 5-Methylcytosine; Amyotrophic Lateral Sclerosis; Brain; C9orf72 Protein; Coculture Techniques; CpG Islands; Cytosine; DNA Methylation; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Lymphocytes; Motor Neurons; Mutation; Nanog Homeobox Protein; Nestin; Promoter Regions, Genetic; Proteins; RNA, Messenger; SOXB1 Transcription Factors; Time Factors | 2016 |
De novo DNA methylation drives 5hmC accumulation in mouse zygotes.
Topics: 5-Methylcytosine; Animals; Biomarkers; Cellular Reprogramming; Chromatography, Liquid; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Embryo Culture Techniques; Epigenesis, Genetic; Fertilization in Vitro; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Kinetics; Mass Spectrometry; Mice; Mice, Knockout; Proto-Oncogene Proteins; Zygote | 2016 |
Ultrasensitive determination of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA by sheathless interfaced capillary electrophoresis-mass spectrometry.
Topics: 5-Methylcytosine; Cytosine; DNA; Electrophoresis, Capillary; Genomics; Limit of Detection; Spectrometry, Mass, Electrospray Ionization | 2016 |
Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Cytosine; DNA Methylation; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Urogenital Neoplasms | 2016 |
RNA biochemistry. Transcriptome-wide distribution and function of RNA hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Brain; Cell Line; Cytosine; Dioxygenases; Drosophila melanogaster; Methylation; RNA, Messenger; Transcriptome | 2016 |
A twist in zygotic reprogramming.
Topics: 5-Methylcytosine; Animals; Cellular Reprogramming; Cytosine; DNA Methylation; Epigenesis, Genetic; Zygote | 2016 |
Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs.
Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Epigenesis, Genetic; Evolution, Molecular; Mice; Mouse Embryonic Stem Cells; Multiprotein Complexes; Signal Transduction | 2016 |
Modified Nucleotides for Discrimination between Cytosine and the Epigenetic Marker 5-Methylcytosine.
Topics: 5-Methylcytosine; Cytosine; Epigenesis, Genetic; Genetic Markers; Nucleotides; Real-Time Polymerase Chain Reaction | 2016 |
Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain.
Topics: 5-Methylcytosine; Base Sequence; Binding Sites; Calorimetry; Crystallography, X-Ray; Cytosine; DNA; Histidine; Methyltransferases; Molecular Dynamics Simulation; Oligopeptides; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins | 2016 |
5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability.
Topics: 5-Methylcytosine; Animals; Aphidicolin; Cell Line; CRISPR-Cas Systems; Cytosine; Dioxygenases; DNA Damage; DNA Methylation; DNA Repair; DNA Replication; DNA-Binding Proteins; Epigenesis, Genetic; Genome; Genomic Instability; HeLa Cells; Histones; Human Embryonic Stem Cells; Humans; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins; Rad51 Recombinase; Tumor Suppressor p53-Binding Protein 1 | 2016 |
5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Antibodies; Astrocytoma; Biomarkers, Tumor; Brain; Central Nervous System Neoplasms; Cytosine; Female; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Ki-67 Antigen; Male; Middle Aged; Mutation; Neoplasm Grading; Prognosis; Spinal Cord; Survival Analysis | 2016 |
Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Base Sequence; Cell Differentiation; Cytosine; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genome-Wide Association Study; Germinal Center; Interleukin-4; Interleukins; Macrophages; Mice; Mice, Transgenic; Molecular Sequence Data; Proto-Oncogene Proteins c-bcl-6; Receptors, Interleukin-7; Signal Transduction; STAT5 Transcription Factor; T-Lymphocytes, Helper-Inducer | 2016 |
Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.
Topics: 5-Methylcytosine; Cerebellar Cortex; Cerebellum; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Genome, Human; Humans; Sequence Analysis, DNA; Sulfites | 2016 |
TET1 contributes to neurogenesis onset time during fetal brain development in mice.
Topics: 5-Methylcytosine; Animals; Biomarkers; Brain; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genetic Vectors; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neurons; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction | 2016 |
Control of Foxp3 stability through modulation of TET activity.
Topics: 5-Methylcytosine; Animals; Ascorbic Acid; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Forkhead Transcription Factors; HEK293 Cells; Humans; Male; Mice; Protein Stability; Proto-Oncogene Proteins; T-Lymphocytes, Regulatory | 2016 |
Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability.
Topics: 5-Methylcytosine; Biomechanical Phenomena; Cytosine; DNA; DNA Methylation; Molecular Dynamics Simulation; Nucleosomes; Oxidation-Reduction | 2016 |
Methylation profiling by bisulfite sequencing analysis of the mtDNA Non-Coding Region in replicative and senescent Endothelial Cells.
Topics: 5-Methylcytosine; Cytosine; DNA, Intergenic; DNA, Mitochondrial; Endothelial Cells; Humans; Mitochondria; Sequence Analysis, DNA; Sulfites | 2016 |
Ten-Eleven Translocation Genes are Downregulated in Endometriosis.
Topics: 5-Methylcytosine; Adult; Aged; Case-Control Studies; Cytosine; Dioxygenases; DNA-Binding Proteins; Endometriosis; Endometrium; Epigenesis, Genetic; Female; Fibroblasts; Humans; Hysterectomy; Menstrual Cycle; Middle Aged; Mixed Function Oxygenases; Primary Cell Culture; Proto-Oncogene Proteins; Signal Transduction; Stromal Cells | 2016 |
[Expression and clinical significance of 5hmC in bladder urothelial carcinoma].
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cytosine; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Prognosis; Urinary Bladder Neoplasms | 2016 |
Hydroxymethylation of microRNA-365-3p Regulates Nociceptive Behaviors via Kcnh2.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; Disease Models, Animal; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Formaldehyde; Gene Expression Regulation; HEK293 Cells; Humans; Male; Mice; Mice, Inbred Strains; MicroRNAs; Pain; Phosphopyruvate Hydratase; Promoter Regions, Genetic; Proto-Oncogene Proteins; Spinal Cord; Time Factors | 2016 |
Analysis of Ferrous on Ten-Eleven Translocation Activity and Epigenetic Modifications of Early Mouse Embryos by Fluorescence Microscopy.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cytosine; Dioxygenases; DNA-Binding Proteins; Embryo, Mammalian; Epigenesis, Genetic; Ferrous Compounds; Mice; Microscopy, Fluorescence; Octamer Transcription Factor-3; Proto-Oncogene Proteins | 2016 |
5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma.
Topics: 5-Methylcytosine; Adenoma; Adolescent; Adult; Aged; Blotting, Western; Case-Control Studies; Cytosine; DNA-Binding Proteins; Humans; Middle Aged; Mixed Function Oxygenases; Parathyroid Glands; Parathyroid Neoplasms; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Young Adult | 2016 |
A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways.
Topics: 5-Methylcytosine; Bayes Theorem; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Humans; Oxidation-Reduction; Sequence Analysis, DNA | 2016 |
Increased 5-hydroxymethylcytosine in CD4(+) T cells in systemic lupus erythematosus.
Topics: 5-Methylcytosine; Adult; Autoimmunity; Case-Control Studies; CD4-Positive T-Lymphocytes; Chromatin Immunoprecipitation; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Humans; Lupus Erythematosus, Systemic; Male; Promoter Regions, Genetic; Protein Binding; Receptors, Interleukin-15; Receptors, Steroid; Repressor Proteins; RNA, Messenger; Severity of Illness Index; Suppressor of Cytokine Signaling 1 Protein; Young Adult | 2016 |
Single-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion identifies evolutionarily unconserved CpGs as TET targets.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; CpG Islands; Cytosine; DNA; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Epigenomics; Exonucleases; Mice; Sequence Analysis, DNA; Staining and Labeling | 2016 |
Simultaneous single-molecule epigenetic imaging of DNA methylation and hydroxymethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Mice; Molecular Imaging | 2016 |
Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Heart Ventricles; Hippocampus; Male; Mice; Mice, Inbred C57BL; Protons | 2016 |
Loss of 5-Hydroxymethylcytosine Is an Independent Unfavorable Prognostic Factor for Esophageal Squamous Cell Carcinoma.
Topics: 5-Methylcytosine; Carcinoma, Squamous Cell; Cytosine; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Prognosis | 2016 |
TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer's disease hippocampus.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cytosine; DNA Methylation; Female; Genome-Wide Association Study; Hippocampus; Humans; Male; Membrane Glycoproteins; Middle Aged; Receptors, Immunologic; Up-Regulation | 2016 |
Epigenomics meets splicing through the TETs and CTCF.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Epigenomics; RNA Splicing | 2016 |
Hydroxymethylation is uniquely distributed within term placenta, and is associated with gene expression.
Topics: 5-Methylcytosine; Cytosine; DNA; Female; Gene Expression Regulation; Humans; Infant, Newborn; Placenta; Pregnancy | 2016 |
Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader.
Topics: 5-Methylcytosine; CCAAT-Enhancer-Binding Proteins; Chromatin; Cytosine; DNA-Binding Proteins; HEK293 Cells; Humans; Ubiquitin-Protein Ligases | 2016 |
OxyBS: estimation of 5-methylcytosine and 5-hydroxymethylcytosine from tandem-treated oxidative bisulfite and bisulfite DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Humans; Likelihood Functions; Microarray Analysis; Sequence Analysis, DNA | 2016 |
Base-resolution profiling of active DNA demethylation using MAB-seq and caMAB-seq.
Topics: 5-Methylcytosine; Animals; Cell Line; Cytosine; DNA; DNA Methylation; DNA Modification Methylases; Mice; Sequence Analysis, DNA; Sulfites | 2016 |
Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis.
Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Line; CpG Islands; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Mice; Sequence Analysis, DNA; Sulfites | 2016 |
TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.
Topics: 5-Methylcytosine; Animals; B-Lymphocytes; Base Sequence; Cell Line; Cytosine; Dioxygenases; DNA Repair; DNA-Binding Proteins; Epigenesis, Genetic; Fibroblasts; Genomic Instability; Humans; Hydroxylation; Megakaryocyte Progenitor Cells; Mice; Mutagenesis; Proto-Oncogene Proteins; S Phase; Thymine DNA Glycosylase; Tumor Suppressor Protein p53 | 2016 |
5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Cell Culture Techniques; Cytosine; DNA Methylation; DNA, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; Sequence Analysis; Transcriptome; Up-Regulation | 2016 |
Simple and accurate single base resolution analysis of 5-hydroxymethylcytosine by catalytic oxidative bisulfite sequencing using micelle incarcerated oxidants.
Topics: 5-Methylcytosine; Adamantane; Animals; Cyclic N-Oxides; Cytosine; DNA, Single-Stranded; Embryonic Stem Cells; Iodobenzenes; Mice; Micelles; Onium Compounds; Oxidants; Oxidation-Reduction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Sulfites; Temperature | 2016 |
Isocitrate Dehydrogenase 2 Dysfunction Contributes to 5-hydroxymethylcytosine Depletion in Gastric Cancer Cells.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Female; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Stomach Neoplasms | 2016 |
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report | 2016 |
Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry.
Topics: 5-Methylcytosine; Antibodies; Cytosine; DNA Methylation; Humans; Immunohistochemistry; Oxidation-Reduction | 2016 |
LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA Repair; DNA-Binding Proteins; Forkhead Transcription Factors; Humans; Oxidation-Reduction; Research Design; Sequence Analysis, DNA | 2016 |
Discrimination between 5-Hydroxymethylcytosine and 5-Methylcytosine in DNA via Selective Electrogenerated Chemiluminescence (ECL) Labeling.
Topics: 5-Methylcytosine; Biosensing Techniques; Cytosine; DNA; DNA Probes; Humans; Limit of Detection; Luminescence; Luminol; Nucleic Acid Hybridization; Oxidation-Reduction; Ruthenium | 2016 |
Preferential 5-Methylcytosine Oxidation in the Linker Region of Reconstituted Positioned Nucleosomes by Tet1 Protein.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Nucleosomes; Oxidation-Reduction | 2016 |
TET1-Mediated Oxidation of 5-Formylcytosine (5fC) to 5-Carboxycytosine (5caC) in RNA.
Topics: 5-Methylcytosine; Base Sequence; Biocatalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytosine; Humans; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Recombinant Proteins; RNA; Tandem Mass Spectrometry | 2017 |
Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
Topics: 5-Methylcytosine; Catalytic Domain; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA Repair; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oxidation-Reduction; Protein Binding; Protein Domains; Substrate Specificity; Thymine DNA Glycosylase | 2016 |
A reusable laser wrapped graphene-Ag array based SERS sensor for trace detection of genomic DNA methylation.
Topics: 5-Methylcytosine; Antibodies, Immobilized; Biosensing Techniques; Cell Line, Tumor; Cytosine; DNA; DNA Methylation; Equipment Design; Gold; Graphite; Humans; Metal Nanoparticles; Reproducibility of Results; Silver; Spectrum Analysis, Raman | 2017 |
Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA.
Topics: 5-Methylcytosine; Ascorbic Acid; Cytosine; DNA; DNA Methylation; HCT116 Cells; Humans; Mixed Function Oxygenases; Oxidation-Reduction; Pentoxyl; Proto-Oncogene Proteins; Spectrometry, Mass, Electrospray Ionization; Thymine | 2016 |
Tet1-dependent epigenetic modification of BDNF expression in dorsal horn neurons mediates neuropathic pain in rats.
Topics: 5-Methylcytosine; Animals; Brain-Derived Neurotrophic Factor; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neuralgia; Posterior Horn Cells; Promoter Regions, Genetic; Rats; Spinal Nerves | 2016 |
Raman spectroscopy and quantum-mechanical analysis of tautomeric forms in cytosine and 5-methylcytosine on gold surfaces.
Topics: 5-Methylcytosine; Adsorption; Cytosine; Gold; Mechanical Phenomena; Quantum Theory; Spectrum Analysis, Raman; Stereoisomerism; Surface Properties; Thermodynamics; Vibration | 2017 |
Elevated 5-hydroxymethycytosine and cell apoptosis induced by tetrachloro-1,4-benzoquinone in mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Apoptosis; Chloranil; Cytosine; Fungicides, Industrial; Mice; Mouse Embryonic Stem Cells; Toxicity Tests | 2017 |
Tetrachloro-1,4-benzoquinone induces apoptosis of mouse embryonic stem cells.
Topics: 5-Methylcytosine; Animals; Apoptosis; Chloranil; Cytosine; Fungicides, Industrial; Mice; Mouse Embryonic Stem Cells; Toxicity Tests | 2017 |
Detecting DNA cytosine methylation using nanopore sequencing.
Topics: 5-Methylcytosine; Cell Line, Tumor; CpG Islands; Cytosine; DNA Methylation; Escherichia coli; Genome, Human; Humans; Markov Chains; Nanopores | 2017 |
Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated
Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cerebellar Neoplasms; Child; Cytosine; Ependymoma; Gene Expression; Humans; Immunohistochemistry; Medulloblastoma; Mixed Function Oxygenases; Proto-Oncogene Proteins; Up-Regulation | 2017 |
Combinatorial DNA methylation codes at repetitive elements.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; DNA Transposable Elements; Epigenesis, Genetic; Fibroblasts; Genome; Mice; Mouse Embryonic Stem Cells; Primary Cell Culture; Repetitive Sequences, Nucleic Acid; Thymine DNA Glycosylase | 2017 |
Differential expression of ten-eleven translocation genes in endometrial cancers.
Topics: 5-Methylcytosine; Aged; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Endometrial Neoplasms; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins | 2017 |
DNA Hydroxymethylation by Ten-eleven Translocation Methylcytosine Dioxygenase 1 and 3 Regulates Nociceptive Sensitization in a Chronic Inflammatory Pain Model.
Topics: 5-Methylcytosine; Animals; Chronic Pain; Cytosine; Dioxygenases; Disease Models, Animal; DNA Methylation; DNA-Binding Proteins; Inflammation; Male; Mice; Nociceptive Pain; Proto-Oncogene Proteins; Signal Transduction; Spinal Cord | 2017 |
Heavy Metals Induce Decline of Derivatives of 5-Methycytosine in Both DNA and RNA of Stem Cells.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Metals, Heavy; Mice; RNA; Stem Cells; Tandem Mass Spectrometry | 2017 |
APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA.
Topics: 5-Methylcytosine; Base Sequence; Cytidine Deaminase; Cytosine; DNA; DNA Methylation; Humans; In Vitro Techniques; Kinetics; Models, Biological; Oxidation-Reduction; Proteins; Recombinant Proteins; Substrate Specificity | 2017 |
Effect of cadmium on cytosine hydroxymethylation in gastropod hepatopancreas.
Topics: 5-Methylcytosine; Animals; Cadmium; Cytosine; Hepatopancreas; Humans; Snails; Water Pollutants, Chemical | 2017 |
Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex.
Topics: 5-Methylcytosine; Adult; Animals; Base Sequence; Cell Nucleus; Conserved Sequence; Cytosine; DNA Methylation; Epigenesis, Genetic; Frontal Lobe; Humans; Male; Mice; Mice, Inbred C57BL; Neurons; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Single-Cell Analysis | 2017 |
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages.
Topics: 5-Methylcytosine; Adult; Aged; Animals; Cell-Free Nucleic Acids; Circulating Tumor DNA; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms | 2017 |
5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes.
Topics: 5-Methylcytosine; Animals; Cytosine; Demethylation; DNA Methylation; Epigenesis, Genetic; Gene Expression; Methyl-CpG-Binding Protein 2; Mice; Mitosis; Neurons; Promoter Regions, Genetic | 2017 |
Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks.
Topics: 5-Methylcytosine; Cytosine; DNA; Electrophoresis, Polyacrylamide Gel; Epigenesis, Genetic; Gene Expression Regulation; Hydrogen-Ion Concentration; Proteins; Spectrometry, Mass, Electrospray Ionization; Temperature; Transcription, Genetic | 2017 |
Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter.
Topics: 5-Methylcytosine; Animals; Base Sequence; CpG Islands; Cyclic AMP Response Element-Binding Protein; Cytosine; DNA; DNA Methylation; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Protein Binding; Thymine DNA Glycosylase | 2017 |
Understanding the influence of antipsychotic drugs on global methylation events and its relevance in treatment response.
Topics: 5-Methylcytosine; Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Female; Haloperidol; Hep G2 Cells; Humans; Male; MicroRNAs; Olanzapine; Pharmacogenetics; Schizophrenia; Treatment Outcome | 2018 |
Electrochemical signal-amplified detection of 5-methylcytosine and 5-hydroxymethylcytosine in DNA using glucose modification coupled with restriction endonucleases.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA Restriction Enzymes; Electrochemical Techniques; Electrodes; Glucose; Gold; Humans; Nucleic Acid Hybridization | 2018 |
Excision of the doubly methylated base
Topics: 5-Methylcytosine; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA-Formamidopyrimidine Glycosylase; Epigenesis, Genetic; Escherichia coli; Escherichia coli Proteins; Humans; Methylation | 2018 |
Two are better than one: HPoxBS - hairpin oxidative bisulfite sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Mice; Oxidation-Reduction; Proto-Oncogene Proteins; Sulfites | 2018 |
Global DNA 5-Hydroxymethylcytosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma.
Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cytosine; DNA, Neoplasm; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging | 2019 |
Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.
Topics: 5-Methylcytosine; Adult; Aged; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Receptors, Estrogen; Tissue Array Analysis | 2018 |
Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
Topics: 5-Methylcytosine; Crystallography, X-Ray; Cytosine; DNA; DNA Restriction Enzymes; Escherichia coli; Escherichia coli Proteins; Models, Molecular; Molecular Structure; Protein Binding; Protein Domains | 2018 |
Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase.
Topics: 5-Methylcytosine; Chromatography, Liquid; Cytosine; Dioxygenases; DNA; DNA Demethylation; DNA-Binding Proteins; Enzyme Assays; Humans; Proto-Oncogene Proteins; Tandem Mass Spectrometry | 2018 |
SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cells, Cultured; Cytosine; DNA Demethylation; DNA Repair; Embryonic Stem Cells; Humans; Mice; Multiprotein Complexes; Protein Multimerization; Sumoylation; X-ray Repair Cross Complementing Protein 1 | 2019 |
Structural basis for effects of CpA modifications on C/EBPβ binding of DNA.
Topics: 5-Methylcytosine; CCAAT-Enhancer-Binding Protein-beta; Conserved Sequence; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; E-Box Elements; Gene Expression Regulation; Promoter Regions, Genetic; Protein Conformation; Thymine; Transcription Factor AP-1 | 2019 |
Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain.
Topics: 5-Methylcytosine; Animals; Brain; Cerebellar Cortex; Cerebellum; Chromosome Mapping; CpG Islands; Cytosine; DNA Methylation; Female; Genome; Haplotypes; Mice; Mice, Inbred C57BL; Olfactory Bulb; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA | 2018 |
Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cryopreservation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Fertilization in Vitro; Metaphase; Mice; Morula; Oocytes; Oogenesis; Pregnancy; Proto-Oncogene Proteins; Vitrification | 2019 |
Diversity of cytosine methylation across the fungal tree of life.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Evolution, Molecular; Fungi; Genome, Fungal; Phylogeny | 2019 |
Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis.
Topics: 5-Methylcytosine; Animals; Cadherins; Cell Differentiation; Cell Lineage; CRISPR-Associated Protein 9; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Oncogene Proteins, Fusion; Pregnancy; Proto-Oncogene Proteins; Transcription Factors; Transcriptome | 2019 |
Biochemical reconstitution of UV-induced mutational processes.
Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine Methylases; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Single-Stranded; Humans; Melanoma; Models, Genetic; Mutagenesis; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Transcriptome; Ultraviolet Rays | 2019 |
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro.
Topics: 5-Methylcytosine; AlkB Enzymes; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Computational Biology; CpG Islands; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Molecular Structure; Oxidation-Reduction | 2019 |
5-Methylcytosine is Oxidized to the Natural Metabolites of TET Enzymes by a Biomimetic Iron(IV)-Oxo Complex.
Topics: 5-Methylcytosine; Biomimetic Materials; Cerium; Coordination Complexes; Cytosine; Dioxygenases; Epigenesis, Genetic; Iron; Kinetics; Oxidation-Reduction; Thermodynamics | 2019 |
Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter.
Topics: 5-Methylcytosine; Animals; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Gene Library; Rats; Sequence Analysis, DNA; Sulfites | 2019 |
MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.
Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation, Leukemic; Humans; Mice; Mice, Transgenic; Mixed Function Oxygenases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc | 2019 |
The clinical values of dysregulated DNA methylation and demethylation intermediates in acute lymphoblastic leukemia.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Area Under Curve; Biomarkers, Tumor; Cell Lineage; Child; Cytosine; Demethylation; DNA Methylation; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Oxidation-Reduction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; ROC Curve; Young Adult | 2019 |
Mapping Retinoic Acid-Dependant 5mC Derivatives in Mouse Embryonic Fibroblasts.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Fibroblasts; Kruppel-Like Transcription Factors; Methyltransferases; Mice; Molecular Structure; Sequence Analysis, DNA; Tretinoin | 2019 |
Polymerization retardation isothermal amplification (PRIA): a strategy enables sensitively quantify genome-wide 5-methylcytosine oxides rapidly on handy instruments with nanoscale sample input.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; DNA-Directed DNA Polymerase; Epigenomics; Genome; Humans; Mice; Oxides; Polymerase Chain Reaction; Polymerization; Rats | 2019 |
Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Alzheimer Disease; Biomarkers; Cytosine; Disease Progression; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Humans; Male; Neurons | 2019 |
Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Topics: 5-Methylcytosine; Binding Sites; Catalytic Domain; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA Restriction Enzymes; Escherichia coli; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Stereoisomerism | 2019 |
Epigenetic modification of cytosines fine tunes the stability of i-motif DNA.
Topics: 5-Methylcytosine; Cell Line; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Nucleotide Motifs | 2020 |
Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Protozoan; Epigenesis, Genetic; Erythrocytes; Genome, Protozoan; High-Throughput Nucleotide Sequencing; Humans; Hydroxylation; Plasmodium falciparum; RNA, Messenger | 2020 |
Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; Epigenesis, Genetic; Genome, Plant; Mass Spectrometry; Norway; Picea | 2019 |
Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads.
Topics: 5-Methylcytosine; Animals; Base Sequence; CCAAT-Enhancer-Binding Proteins; CpG Islands; Cytosine; Epigenesis, Genetic; Mice; Molecular Dynamics Simulation; Protein Binding; Protein Domains; Substrate Specificity; Ubiquitin-Protein Ligases | 2020 |
DNA demethylation is a driver for chick retina regeneration.
Topics: 5-Methylcytosine; Animals; Avian Proteins; Chick Embryo; Chromatin; Cytosine; Dioxygenases; DNA Methylation; Fibroblast Growth Factor 2; Histone Code; Regeneration; Retinal Pigment Epithelium | 2020 |
Timing of Cytosine Methylation on Newly Synthesized RNA by Electron Microscopy.
Topics: 5-Methylcytosine; Chromatin; Cytosine; Epigenesis, Genetic; HeLa Cells; Humans; Immunohistochemistry; Methylation; Microscopy, Electron; RNA Polymerase II; RNA Precursors; RNA Processing, Post-Transcriptional; RNA, Messenger; Staining and Labeling; Transcription, Genetic; Uridine | 2020 |
Quantitative analysis of global 5-methyl- and 5-hydroxymethylcytosine in TET1 expressed HEK293T cells.
Topics: 5-Methylcytosine; Animals; Biosensing Techniques; Cytosine; DNA Methylation; HEK293 Cells; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins | 2020 |
Quantification of DNA Modifications Using Two-Dimensional Ultraperformance Liquid Chromatography Tandem Mass Spectrometry (2D-UPLC-MS/MS).
Topics: 5-Methylcytosine; Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Hydrolysis; Tandem Mass Spectrometry; Zebrafish | 2021 |
Immunochemical Detection of Modified Cytosine Species in Mammalian Preimplantation Embryos.
Topics: 5-Methylcytosine; Animals; Blastocyst; Cytosine; DNA Methylation; Embryo, Mammalian; Embryonic Development; Humans; Immunochemistry; Mammals; Microscopy, Confocal; Zygote | 2021 |
Detection of Low-Abundance DNA Modifications Using Signal Amplification-Based Immunocytochemistry.
Topics: 5-Methylcytosine; Animals; Antibodies; Cell Nucleus; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Immunohistochemistry; Pentoxyl; Peroxidase | 2021 |
Immunohistochemical Detection of Modified Cytosine Bases in Rodent Brain.
Topics: 5-Methylcytosine; Animals; Antibodies; Brain; Cell Nucleus; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Immunohistochemistry; Mice; Peroxidase; Rats; Rodentia | 2021 |
Immunohistochemical Detection of 5-Hydroxymethylcytosine and 5-Carboxylcytosine in Sections of Zebrafish Embryos.
Topics: 5-Methylcytosine; Animals; Antibodies; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Methylation; Embryo, Nonmammalian; Immunohistochemistry; Zebrafish | 2021 |
Immunochemical Detection of Modified Species of Cytosine in Plant Tissues.
Topics: 5-Methylcytosine; Antibodies; Cell Nucleus; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Fluorescent Dyes; Immunohistochemistry; Plants | 2021 |
Antigen Retrieval for Immunostaining of Modified Cytosine Species.
Topics: 5-Methylcytosine; Animals; Antibodies; Antigens; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Fluorescent Antibody Technique; Humans | 2021 |
Analysis of 5-Hydroxymethyluracil Levels Using Flow Cytometry.
Topics: 5-Methylcytosine; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Humans; Oxidation-Reduction; Pentoxyl; Single-Cell Analysis; Tandem Mass Spectrometry; Thymine | 2021 |
Analysis of 5-Carboxylcytosine Distribution Using DNA Immunoprecipitation.
Topics: 5-Methylcytosine; Animals; Chromatin Immunoprecipitation; Cytosine; DNA; DNA Methylation; Humans; Immunoprecipitation | 2021 |
High-Resolution Analysis of 5-Hydroxymethylcytosine by TET-Assisted Bisulfite Sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genome; Humans; Oxidation-Reduction; Sequence Analysis, DNA; Sulfites | 2021 |
Oxidative Bisulfite Sequencing: An Experimental and Computational Protocol.
Topics: 5-Methylcytosine; Animals; Computational Biology; Cytosine; Dioxygenases; DNA; DNA Methylation; High-Throughput Nucleotide Sequencing; Humans; Oxidation-Reduction; Oxidative Stress; Sequence Analysis, DNA; Sulfites | 2021 |
Bisulfite-Free Sequencing of 5-Hydroxymethylcytosine with APOBEC-Coupled Epigenetic Sequencing (ACE-Seq).
Topics: 5-Methylcytosine; Animals; Computational Biology; Cytidine Deaminase; Cytosine; DNA; DNA Methylation; Epigenomics; Humans; Proteins; Sequence Analysis, DNA; Single Molecule Imaging; Sulfites | 2021 |
Design and Application of DNA Modification-Specific Transcription-Activator-Like Effectors.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Epigenomics; Genome; Humans; Transcription Activator-Like Effectors | 2021 |
Integrated Analysis of DNA Methylation, Hydroxymethylation, and Gene Expression Data Using ME-Class2.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression; Gene Silencing; Genome; Genomics; Humans; Machine Learning; Sequence Analysis, DNA | 2021 |
A New Bias Site for Epigenetic Modifications: How Non-Canonical GC Base Pairs Favor Mechanochemical Cleavage of DNA.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; DNA; Epigenesis, Genetic; Nucleic Acid Conformation | 2020 |
bZIP Dimers CREB1, ATF2, Zta, ATF3|cJun, and cFos|cJun Prefer to Bind to Some Double-Stranded DNA Sequences Containing 5-Formylcytosine and 5-Carboxylcytosine.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Basic-Leucine Zipper Transcription Factors; Cytosine; DNA; Mice; Protein Array Analysis; Protein Binding | 2020 |
Enzymatic Hydroxylation and Excision of Extended 5-Methylcytosine Analogues.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Glycosylases; DNA Methylation; DNA Repair; DNA-Binding Proteins; Humans; Hydroxylation; Mice; Naegleria; Oxidation-Reduction; Proto-Oncogene Proteins | 2020 |
Pairwise Proximity-Differentiated Visualization of Single-Cell DNA Epigenetic Marks.
Topics: 5-Methylcytosine; Cell Line; Chromatin; Cytosine; DNA; Humans; Molecular Structure; Single-Cell Analysis | 2021 |
A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
Topics: 5-Methylcytosine; Chromosome Mapping; CpG Islands; Cytosine; DNA; DNA Methylation; Enhancer Elements, Genetic; Epigenesis, Genetic; Genome, Human; Histones; Humans; Organ Specificity; Transcription Factors; Transcriptional Activation | 2020 |
Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans.
Topics: 5-Methylcytosine; Adaptation, Physiological; Animals; Caenorhabditis elegans; CRISPR-Cas Systems; Cytosine; Gene Editing; Heat-Shock Response; Hot Temperature; Leucine; Methyltransferases; Mitochondria; Proline; Protein Biosynthesis; Ribosomes; RNA; RNA Processing, Post-Transcriptional | 2021 |
Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Proteins; CpG Islands; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; DNA, Complementary; Mice; Protein Binding; Sequence Alignment; Ubiquitin-Protein Ligases | 2021 |
One-pot intramolecular cyclization of 5-hydroxymethylcytosine for sequencing DNA hydroxymethylation at single-base resolution.
Topics: 5-Methylcytosine; Cyclization; Cytosine; DNA; DNA Methylation; Prospective Studies; Sequence Analysis, DNA | 2021 |
Effect of cytosine hydroxymethylation on DNA charge transport.
Topics: 5-Methylcytosine; Biophysics; Cytosine; DNA; DNA Methylation; Electrophysiology; Epigenesis, Genetic; Molecular Conformation; Solvents; Temperature | 2021 |
5-Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells.
Topics: 5-Methylcytosine; Base Pairing; Cytosine; DNA; Nucleic Acid Conformation; Thermodynamics | 2021 |
TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites.
Topics: 5-Methylcytosine; CpG Islands; Cytosine; Dioxygenases; DNA Demethylation; DNA Repair; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Oxidation-Reduction; Proto-Oncogene Proteins; Thymine DNA Glycosylase | 2021 |
The chromatin remodelling protein LSH/HELLS regulates the amount and distribution of DNA hydroxymethylation in the genome.
Topics: 5-Methylcytosine; Animals; Chromatin Assembly and Disassembly; Cytosine; DNA; DNA Helicases; DNA Methylation; Fibroblasts; Genome; Mice | 2022 |
Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays.
Topics: 5-Methylcytosine; Computational Biology; Cytosine; DNA; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; High-Throughput Nucleotide Sequencing; Humans; Microarray Analysis; Oxidation-Reduction; Sulfites | 2021 |
Harnessing Alternative Substrates to Probe TET Family Enzymes.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA-Binding Proteins; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; Substrate Specificity | 2021 |
Pearl Necklacelike Strategy Enables Quantification of Global 5-Hydroxymethylcytosine and 5-Formylcytosine by Inductively Coupled Plasma-Atomic Emission Spectrometry.
Topics: 5-Methylcytosine; Cytosine; Spectrum Analysis | 2021 |
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Proliferation; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression; Genetic Loci; Hematopoiesis; Interleukin-4; Isoenzymes; Lipopolysaccharides; Longevity; Macrophages; Mice; Mice, Knockout; T-Lymphocytes; Thymine DNA Glycosylase | 2021 |
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth.
Topics: 5-Methylcytosine; Animals; Cichlids; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic | 2021 |
MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Topics: 5-Methylcytosine; Animals; Cells, Cultured; Chromatin; Cytosine; Dinucleotide Repeats; DNA Methylation; Embryonic Stem Cells; Fibroblasts; Frontal Lobe; Methyl-CpG-Binding Protein 2; Mice; Microsatellite Repeats; Neurons; Nucleic Acid Conformation; Nucleosomes; Oxidation-Reduction; Protein Binding; Protein Domains; Rett Syndrome; Transcription, Genetic | 2021 |
Proteome-Wide Profiling of Readers for DNA Modification.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Models, Animal; Proteome; Transcription Factors | 2021 |
Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms.
Topics: 5-Methylcytosine; Binding Sites; Cytosine; DNA; DNA Repair; Humans; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Protein Binding; Thymine DNA Glycosylase | 2021 |
Modified cytosines
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA-Directed DNA Polymerase; Kinetics; Thermodynamics | 2022 |
Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Mice; R-Loop Structures | 2022 |
Distribution and regulatory roles of oxidized 5-methylcytosines in DNA and RNA of the basidiomycete fungi
Topics: 5-Methylcytosine; Agaricales; Animals; Basidiomycota; Cytosine; DNA Methylation; DNA Transposable Elements; Laccaria; Mammals; RNA | 2022 |
The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription.
Topics: 5-Methylcytosine; Chromatin; Cytosine; DNA Methylation; Histones; Mixed Function Oxygenases; Proto-Oncogene Proteins | 2022 |
Single-molecule analysis of genome-wide DNA methylation by fiber FISH coupled with atomic force microscopy.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; In Situ Hybridization, Fluorescence; Microscopy, Atomic Force | 2022 |
Enhanced nucleosome assembly at CpG sites containing an extended 5-methylcytosine analogue.
Topics: 5-Methylcytosine; Animals; Chromatin; Chromatin Assembly and Disassembly; CpG Islands; Cytosine; DNA; DNA Methylation; Nucleosomes | 2022 |
Quantification of Global DNA Hydroxymethylation Level Using UHRF2 SRA-Luciferase Based on Bioluminescence Resonance Energy Transfer.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; Energy Transfer; Luciferases | 2022 |
Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine.
Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Kinetics; Mammals; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Reading; Transcription Factors | 2022 |
Global analysis of cytosine and adenine DNA modifications across the tree of life.
Topics: 5-Methylcytosine; Adenine; Animals; Cytosine; DNA; DNA Methylation; Eukaryota; Mammals | 2022 |
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Demethylation; DNA Methylation; DNA-Binding Proteins; Endogenous Retroviruses; Gene Expression; Mammals; Mice; Proto-Oncogene Proteins | 2022 |
TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes.
Topics: 5-Methylcytosine; Animals; Chromatin; Core Binding Factor Alpha 1 Subunit; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Mammals; Proto-Oncogene Proteins | 2022 |
Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
Topics: 5-Methylcytosine; Animals; CCAAT-Enhancer-Binding Proteins; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Heterochromatin; Humans; Mice; Mixed Function Oxygenases; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Embryonic Development; Oxidation-Reduction; Zebrafish | 2022 |
Screening of glycosylase activity on oxidative derivatives of methylcytosine: Pedobacter heparinus SMUG2 as a formylcytosine- and carboxylcytosine-DNA glycosylase.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Repair; Humans; Oxidative Stress; Pedobacter; Thymine; Thymine DNA Glycosylase; Uracil; Uracil-DNA Glycosidase | 2022 |
Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis.
Topics: 5-Methylcytosine; Breast Neoplasms; Cell Transformation, Neoplastic; Cytosine; DNA, Intergenic; Female; Humans; Untranslated Regions | 2022 |
Bisulfite-Free and Single-Base Resolution Detection of Epigenetic DNA Modification of 5-Methylcytosine by Methyltransferase-Directed Labeling with APOBEC3A Deamination Sequencing.
Topics: 5-Methylcytosine; Animals; Cytosine; Deamination; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Mammals; Methyltransferases; Sequence Analysis, DNA; Sulfites | 2022 |
Structure and Function of TET Enzymes.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Embryonic Development; Mammals; Oxidation-Reduction | 2022 |
Recent Advances on DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Eukaryota | 2022 |
5-Methyl-cytosine stabilizes DNA but hinders DNA hybridization revealed by magnetic tweezers and simulations.
Topics: 5-Methylcytosine; Cytosine; DNA; Magnetic Phenomena; Nucleic Acid Conformation; Nucleic Acid Hybridization | 2022 |
Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Female; Mammals; Mice; Zygote | 2023 |
Engineered APOBEC3C Sequencing Enables Bisulfite-Free and Direct Detection of DNA Methylation at a Single-Base Resolution.
Topics: 5-Methylcytosine; Cytidine Deaminase; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Sequence Analysis, DNA; Sulfites | 2023 |
5-hydroxymethylcytosine stabilizes transcription by preventing aberrant initiation in gene bodies.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation | 2023 |
A novel one-pot fluorescence tagging and depyrimidination strategy for quantification of global DNA methylation.
Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Methylation | 2023 |
Maternal high-fat diet changes DNA methylation in the early embryo by disrupting the TCA cycle intermediary alpha ketoglutarate.
Topics: 5-Methylcytosine; Animals; Cytosine; Diet, High-Fat; DNA Methylation; Female; Humans; Ketoglutaric Acids; Mice; Obesity, Maternal; Pregnancy; Zygote | 2023 |
Global DNA 5-hydroxymethylcytosine level and its chromosomal distribution in four rye species.
Topics: 5-Methylcytosine; Chromosomes; Cytosine; DNA; DNA Methylation; Secale | 2023 |
Impact of antigen retrieval protocols on the immunohistochemical detection of epigenetic DNA modifications.
Topics: 5-Methylcytosine; Antigens; Carcinoma, Squamous Cell; Citrates; Cytosine; DNA; DNA Methylation; Edetic Acid; Epigenesis, Genetic; Humans; Pepsin A | 2023 |
A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA.
Topics: 5-Methylcytosine; Cytosine; DNA; Oxidation-Reduction | 2023 |
Decrease of 5-hydroxymethylcytosine in hepatitis B virus-related hepatocellular carcinoma: A cross-sectional study.
Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cross-Sectional Studies; Cytosine; DNA Methylation; Hepatitis B virus; Humans; Liver Neoplasms; Mixed Function Oxygenases; Proto-Oncogene Proteins | 2023 |
Direct enzymatic sequencing of 5-methylcytosine at single-base resolution.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Mammals; Sequence Analysis, DNA | 2023 |
A Chemical Model of a TET Enzyme for Selective Oxidation of Hydroxymethyl Cytosine to Formyl Cytosine.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Hydrogen Peroxide; Models, Chemical; Oxidation-Reduction | 2023 |
Uncovering plant epigenetics: new insights into cytosine methylation in rye genomes.
Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Epigenesis, Genetic; Secale | 2023 |
PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Topics: 5-Methylcytosine; Biomedical Research; Cytosine; Databases, Factual; Humans | 2023 |
PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Topics: 5-Methylcytosine; Biomedical Research; Cytosine; Databases, Factual; Humans | 2023 |
Tracking the Early Stage of Triplet-Induced Photodamage in a DNA Dimer and Oligomer Containing 5-Methylcytosine.
Topics: 5-Methylcytosine; Cytosine; DNA; DNA Damage; Pyrimidine Dimers | 2023 |
Dual-Responsive Carbon Quantum Dots for the Simultaneous Detection of Cytosine and 5-Methylcytosine Interpreted by a Machine Learning-Assisted Smartphone.
Topics: 5-Methylcytosine; Carbon; Cytosine; Fluorescent Dyes; Nitrogen; Quantum Dots; Smartphone | 2023 |
Single-cell bisulfite-free 5mC and 5hmC sequencing with high sensitivity and scalability.
Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Mice; Sequence Analysis, DNA; Sulfites | 2023 |