5-methylcytosine has been researched along with azacitidine in 85 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (37.65) | 18.7374 |
1990's | 19 (22.35) | 18.2507 |
2000's | 11 (12.94) | 29.6817 |
2010's | 22 (25.88) | 24.3611 |
2020's | 1 (1.18) | 2.80 |
Authors | Studies |
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Matsuda, M; Yasutomi, M | 1 |
Gartler, SM; Hansen, RS | 1 |
Cosgrove, DE; Cox, GS | 1 |
Bona, R; Cozzi, R; D'Erme, M; Palitti, F; Perticone, P | 1 |
Storch, TG | 1 |
Catravas, GN; Kalinich, JF; Snyder, SL | 1 |
Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N | 1 |
Nyce, J | 1 |
Selker, EU; Stevens, JN | 1 |
Jones, PA; Kautiainen, TL | 1 |
Haaf, T; Ott, G; Scheres, JM; Schmid, M; Wensing, JA | 1 |
Everett, CA; Finch, M; Hart, IR; Ormerod, EJ | 1 |
Holliday, R | 1 |
Fairweather, DS; Fox, M; Margison, GP | 1 |
Gunter, KC; Sneller, MC | 1 |
Heuertz, S; Homman, N; Hors-Cayla, MC | 1 |
Jones, PA; Michalowsky, LA | 2 |
Veselý, J | 1 |
Isham, KR; Kenney, FT; Lee, KL; Rothrock, R | 1 |
Fioretti, MC; Fuschiotti, P; Puccetti, P; Romani, L | 1 |
Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R | 1 |
Farooq, M; Holliday, R; Hunter, JL; Matsumura, T | 1 |
Chandler, LA; Jones, PA | 1 |
Korba, BE; Wilson, VL; Yoakum, GH | 1 |
Ikushima, T | 1 |
Maharajan, V; Pratibha, M; Scarano, E; Tosi, L | 1 |
Bird, S; Cowing, D; Gusella, J; Hoffmann, JW; Steffen, D; Tabin, C; Weinberg, RA | 1 |
Adams, RL; Burdon, RH | 1 |
Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM | 1 |
Harris, JS; Lu, LJ; Randerath, K; Tseng, WC | 1 |
Jones, PA; Momparler, RL; Wilson, VL | 1 |
Cooper, DN | 1 |
Jones, PA; Riggs, AD | 1 |
Jones, PA; Taylor, SM; Wilson, V | 1 |
Constantinides, PA; Jones, PA; Taylor, SM | 1 |
Christman, JK | 1 |
Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA | 1 |
Strobl, JS; Thompson, EB | 1 |
Claeys, KM; Foss, HM; Roberts, CJ; Selker, EU | 1 |
Hsieh, CL | 1 |
Campos, A; Fernández, JL; Gosálvez, J; Goyanes, V; Pereira, S | 1 |
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
Chalasani, S; Dy, L; Essani, K | 1 |
de Capoa, A; Di Leandro, M; Giancotti, P; Grappelli, C; Marotta, MR; Menendez, F; Niveleau, A; Poggesi, I; Reynaud, C | 1 |
Bird, AP | 1 |
Christiansen-Weber, T; Haas, M; Haggblom, C; Vogt, M; Yeargin, J | 1 |
Côté, S; Momparler, RL; Sinnett, D | 1 |
Castilho, A; Heslop-Harrison, JS; Neves, N; Rufini-Castiglione, M; Viegas, W | 1 |
Jones, PA; Robertson, KD | 1 |
Borniquel, S; Callejas, S; Gutiérrez, JC; Martín-González, A | 1 |
Carter, KB; Cauthron, RD; Gan, J; Steinberg, RA; Zhang, YL | 1 |
Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M | 1 |
Ankri, S; Fisher, O; Siman-Tov, R | 1 |
Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K | 1 |
Butler, JS; Ladd, PD; Skalnik, DG | 1 |
Law, RD; Suttle, JC | 1 |
Henson, R; Meng, F; Mize-Berge, J; Patel, T; Wehbe, H | 1 |
Farkas, DL; Gertych, A; Lindsley, E; Tajbakhsh, J; Vishnevsky, E; Wawrowsky, KA | 1 |
Bettuzzi, S; Patra, SK | 1 |
Carambula, SF; Hansen, PJ; Oliveira, LJ | 1 |
Cho, S; Kang, YK; Lee, D; Park, JS; Shin, ST | 1 |
Chen, Y; Love, A; Zhou, FC | 1 |
Borowska, N; Hasterok, R; Idziak, D | 1 |
Feng, YQ; Gao, XD; Tang, Y; Wang, Y; Yuan, BF | 1 |
Chen, ZJ; Huang, XY; Liu, HQ; Sun, L; Wang, HY; Wang, Y; Wu, KL; Xu, ZY; Zhang, D | 1 |
Gertych, A; Oh, JH; Tajbakhsh, J; Wawrowsky, KA; Weisenberger, DJ | 1 |
Cho, IH; Chowdhury, B; Cui, Y; Irudayaraj, J | 1 |
Mandarano, AH; Militello, KT; Simon, RD; Varechtchouk, O | 1 |
Huang, Y; Rao, A | 1 |
Cáceres, ME; Ortiz, JP; Pessino, SC; Podio, M; Pupilli, F; Samoluk, SS; Seijo, JG | 1 |
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC | 1 |
Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A | 1 |
DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
Bohnsack, MT; Günnigmann, MA; Haag, S; Höbartner, C; Kretschmer, J; Warda, AS | 1 |
Brown, H; Chresta, CM; Delpuech, O; Taylor, MA; Wappett, M | 1 |
Anders, NM; Giovinazzo, H; Liu, J; Nelson, WG; Rudek, MA; Vaghasia, A; Wanjiku, T; Yegnasubramanian, S; Zhou, J | 1 |
Cantatore, S; DiNatale, A; Hennick, SM; Lazatin, JC; Mandarano, AH; Militello, KT; Simon, RD | 1 |
Çelik-Uzuner, S; Li, Y; O'Neill, C; Peters, L | 1 |
Chen, L; Gong, F; Guo, Y; Jin, J; Li, R; Ma, RZ; Niu, Y; Shi, X; Zhang, L; Zhang, X | 1 |
Li, H; Luan, P; Peng, W; Wang, K; Xu, Y; Zhang, P; Zhuang, J | 1 |
Abboud, CN; Baty, JD; Cashen, AF; DiPersio, JF; Duncavage, EJ; Fehniger, TA; Fronick, CC; Fulton, RS; Ghobadi, A; Graubert, TA; Hantel, A; Heath, SE; Jacoby, MA; Janke, MR; Khan, N; Knoebel, RW; Lee, YS; Ley, TJ; Link, DC; Luber, K; Miller, CA; O'Laughlin, M; Oh, ST; Petti, AA; Pusic, I; Romee, R; Schroeder, MA; Stock, W; Stockerl-Goldstein, KE; Sukhanova, MJ; Tandon, B; Tomasson, MH; Uy, GL; Vij, R; Walter, MJ; Wartman, LD; Welch, JS; Westervelt, P; Wilson, RK | 1 |
Adam, V; Bacova, R; Cernei, N; Huska, D; Klejdus, B; Ryant, P | 1 |
Bernabeu, R; Pisera-Fuster, A; Zwiller, J | 1 |
12 review(s) available for 5-methylcytosine and azacitidine
Article | Year |
---|---|
Hypomethylation of DNA in the regulation of gene expression.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms | 1988 |
DNA methylation in eukaryotes.
Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin | 1982 |
Eukaryotic DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Differentiation; Chromosome Mapping; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA Replication; Eukaryotic Cells; Gene Expression Regulation; Genes; Genes, Viral; Humans; Methylation; Models, Genetic; Mutation; Transcription, Genetic; Transformation, Genetic | 1983 |
5-methylcytosine, gene regulation, and cancer.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes | 1983 |
DNA modification, differentiation, and transformation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Carcinogens; Cell Differentiation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Fibroblasts; Humans; Methylation; Mice; Papio; Phenotype; Rats; Transformation, Genetic | 1983 |
5-Azacytidine, DNA methylation, and differentiation.
Topics: 5-Methylcytosine; Azacitidine; Cell Differentiation; Cytidine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dosage Compensation, Genetic; Female; Gene Expression Regulation; Genes, Viral; Methylation; Methyltransferases; Nucleic Acids; Phosphorylation; RNA, Transfer; X Chromosome | 1984 |
DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice | 1984 |
The relationship of DNA methylation to cancer.
Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms | 1996 |
DNA methylation: past, present and future directions.
Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Azacitidine; Carcinogens; Chromatin; Cytosine; DNA Methylation; DNA Repair; Forecasting; Gene Expression; Humans; Neoplasms | 2000 |
DNA methylation in ciliates: implications in differentiation processes.
Topics: 5-Methylcytosine; Adenine; Animals; Azacitidine; Cell Differentiation; Cell Nucleus; Ciliophora; Cytosine; DNA Methylation; DNA Modification Methylases; DNA, Protozoan; Gene Expression Regulation; Gene Expression Regulation, Developmental; Paramecium; Protozoan Proteins; Tetrahymena | 2000 |
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Cycle; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation; Humans | 2009 |
Connections between TET proteins and aberrant DNA modification in cancer.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries | 2014 |
1 trial(s) available for 5-methylcytosine and azacitidine
Article | Year |
---|---|
TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Bone Marrow; Decitabine; Exome; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Prospective Studies; Risk Factors; Survival Rate; Tumor Suppressor Protein p53 | 2016 |
72 other study(ies) available for 5-methylcytosine and azacitidine
Article | Year |
---|---|
Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Central Nervous System; Cytosine; DNA; DNA Modification Methylases; Embryo, Mammalian; Immunohistochemistry; In Vitro Techniques; Microscopy, Electron; Proteins; Rats | 1992 |
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Methylation; Phosphoglycerate Kinase; Regulatory Sequences, Nucleic Acid; Restriction Mapping; X Chromosome | 1990 |
Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: variable response to drug treatment and withdrawal.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Butyric Acid; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Dose-Response Relationship, Drug; HeLa Cells; Humans; Methylation; Tumor Cells, Cultured | 1990 |
Persistence of azacytidine-induced SCEs and genomic methylation in CHO cells in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Cycle; Chromatography, High Pressure Liquid; Cricetinae; Cytosine; In Vitro Techniques; Methylation; Sister Chromatid Exchange | 1990 |
Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; DNA; Kinetics; Methylation; Mice; Mice, Inbred C3H; Muscles; Oxygen | 1990 |
Radioprotective properties of DNA methylation-disrupting agents.
Topics: 5-Methylcytosine; Animals; Azacitidine; Butyrates; Butyric Acid; Cell Survival; Cytosine; Depression, Chemical; DNA; In Vitro Techniques; Methylation; Radiation-Protective Agents; Stimulation, Chemical | 1991 |
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains | 1991 |
Gene silencing in mammalian cells by direct incorporation of electroporated 5-methyl-2'-deoxycytidine 5'-triphosphate.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytosine; Deoxycytosine Nucleotides; Drug Resistance; Gene Expression Regulation; Methylation; Mutagenesis; Thioguanine | 1991 |
DNA methylation at asymmetric sites is associated with numerous transition mutations.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Biological Evolution; Cytosine; DNA, Ribosomal; Methylation; Mutation; Neurospora crassa | 1985 |
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1986 |
Heterochromatin in the chromosomes of the gorilla: characterization with distamycin A/DAPI, D287/170, chromomycin A3, quinacrine, and 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cells, Cultured; Chromomycin A3; Chromosome Banding; Cytosine; Distamycins; DNA; Female; Fluorescent Dyes; Gorilla gorilla; Heterochromatin; Indoles; Lymphocytes; Male; Nucleolus Organizer Region; Primates; Quinacrine; Species Specificity; Staining and Labeling | 1986 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis | 1986 |
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation | 1986 |
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytosine; DNA; Fibroblasts; Humans; Methylation | 1987 |
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells.
Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabine; DNA, Neoplasm; Ethyl Methanesulfonate; Gene Expression Regulation; Lymphoma; Methylation; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Thy-1 Antigens | 1987 |
Time dependence of X gene reactivation induced by 5-azacytidine: possible progressive restructuring of chromatin.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Division; Cell Line; Chromatin; Cricetinae; Cytosine; Dosage Compensation, Genetic; Enzyme Induction; Female; Gene Expression Regulation; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylation | 1987 |
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice | 1987 |
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases | 1987 |
Changes in hepatic differentiation following treatment of rat fetuses with 5-azacytidine.
Topics: 5-Methylcytosine; alpha-Fetoproteins; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Hematopoiesis; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; RNA, Messenger; Tyrosine Transaminase | 1988 |
Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Clone Cells; Cytosine; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Phenotype; Triazenes | 1989 |
Gene structure and transcription in mouse cells with extensively demethylated DNA.
Topics: 5-Methylcytosine; Animals; Azacitidine; Chromatin; Clone Cells; Cytosine; Decitabine; DNA; Gene Expression Regulation; Methylation; Mice; Transcription, Genetic | 1989 |
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors | 1989 |
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span.
Topics: 5-Methylcytosine; Azacitidine; Base Composition; Cell Division; Cell Transformation, Viral; Cytosine; Decitabine; DNA; Humans; In Vitro Techniques; Methylation; Simian virus 40 | 1989 |
Induction of hepatitis B virus core gene in human cells by cytosine demethylation in the promoter.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Hepatitis B Core Antigens; Humans; Methylation; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Virus Replication | 1985 |
SCE and DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytosine; Deer; DNA; DNA Replication; Female; Fibroblasts; Male; Methylation; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange | 1984 |
Analogues of 5-methyl cytosine and early embryonic development.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytosine; DNA; Embryo, Nonmammalian; Gene Expression Regulation; Methylation; Sea Urchins | 1982 |
DNA methylation affecting the expression of murine leukemia proviruses.
Topics: 5-Methylcytosine; AKR murine leukemia virus; Animals; Azacitidine; Cell Line; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Leukemia Virus, Murine; Methylation; Mice; Moloney murine leukemia virus; Rats; Recombination, Genetic; Transfection | 1982 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin | 1983 |
Specific effects of 5-fluoropyrimidines and 5-azapyrimidines on modification of the 5 position of pyrimidines, in particular the synthesis of 5-methyluracil and 5-methylcytosine in nucleic acids.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytidine; Cytosine; DNA; Liver; Methylation; Mice; Pyrimidines; RNA, Transfer; Thymine | 1983 |
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action.
Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice | 1983 |
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype | 1984 |
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic | 1984 |
Methylation of either cytosine in the recognition sequence CGCG inhibits ThaI cleavage of DNA.
Topics: 5-Methylcytosine; Adenoma; Animals; Azacitidine; Base Sequence; Cell Line; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Pituitary Neoplasms; Rats; Substrate Specificity | 1984 |
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine | 1993 |
Dependence of transcriptional repression on CpG methylation density.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Cell Nucleus; Cytosine; DNA-Cytosine Methylases; Gene Expression Regulation; Methylation; Transcription, Genetic; Transfection | 1994 |
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
Topics: 5-Methylcytosine; Adult; Azacitidine; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, Pair 9; Cytosine; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Methylation; Microscopy, Electron | 1994 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Isolation of Escherichia coli mutants lacking methylcytosine-dependent restriction systems for cloning extensively methylated frog virus 3 DNA.
Topics: 5-Methylcytosine; Ampicillin Resistance; Azacitidine; Base Sequence; Clone Cells; Cloning, Molecular; Cytosine; DNA Transposable Elements; DNA-Binding Proteins; DNA-Cytosine Methylases; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iridoviridae; Methylation; Molecular Sequence Data; Mutation; Plasmids; Substrate Specificity; Transformation, Genetic | 1993 |
Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Azacitidine; Cells, Cultured; Centromere; Chromosomes, Human; Cytosine; DNA Methylation; Heterochromatin; Humans; Karyotyping; Lymphocytes; Male | 1996 |
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line, Transformed; Cellular Senescence; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation; Genes, p16; Genes, p53; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome | 1998 |
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured | 1998 |
5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine.
Topics: 5-Methylcytosine; Azacitidine; Chromosome Mapping; Cytosine; DNA Methylation; DNA, Plant; DNA, Ribosomal; Edible Grain; Genome, Plant; Plant Roots; Secale; Triticum | 1999 |
On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells.
Topics: 5-Methylcytosine; Animals; Arginine; Azacitidine; Cytosine; Dinucleoside Phosphates; DNA Methylation; DNA, Neoplasm; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Mice; Mutagenesis; Tumor Cells, Cultured | 1999 |
A systematic profile of DNA methylation in human cancer cell lines.
Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured | 2003 |
Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite Entamoeba histolytica.
Topics: 5-Methylcytosine; Amino Acid Sequence; Animals; Azacitidine; Base Sequence; Blotting, Western; Cell Nucleus; CHO Cells; Chromatography, Affinity; Cloning, Molecular; Cricetinae; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Protozoan; DNA, Ribosomal; Entamoeba histolytica; Genome, Protozoan; Humans; Liver Abscess; Mesocricetus; Molecular Sequence Data; Protein Transport; RNA, Messenger; Substrate Specificity; Virulence | 2004 |
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic | 2004 |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Cell Line; Codon, Initiator; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Hematopoietic System; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; K562 Cells; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; NIH 3T3 Cells; Promoter Regions, Genetic; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Transcription Initiation Site; Transfection | 2004 |
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.
Topics: 5-Methylcytosine; Acetylation; Azacitidine; Chromatin Assembly and Disassembly; Cytosine; DNA Methylation; Epigenesis, Genetic; Histones; Hydroxamic Acids; Solanum tuberosum; Transcription, Genetic | 2005 |
Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression.
Topics: 5-Methylcytosine; Azacitidine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; Decitabine; DNA Methylation; ErbB Receptors; Humans; Interleukin-6; Promoter Regions, Genetic | 2006 |
Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment.
Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Cell Line; Cell Nucleus; DNA; DNA Methylation; Drug Evaluation, Preclinical; Imaging, Three-Dimensional; Indoles; Mice; Octreotide; Pituitary Gland; Software | 2009 |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.
Topics: 5-Methylcytosine; Animals; Apoptosis; Azacitidine; Blastocyst; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytosine; Decitabine; DNA Fragmentation; DNA Methylation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids | 2009 |
Active loss of DNA methylation in two-cell stage goat embryos.
Topics: 5-Methylcytosine; Animals; Azacitidine; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Embryo, Mammalian; Enzyme Inhibitors; Female; Goats; Histones; Immunohistochemistry; Lysine; Male; Methylation; Zygote | 2010 |
Cellular DNA methylation program during neurulation and its alteration by alcohol exposure.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neural Tube; Neurulation; Pregnancy; Repressor Proteins; Transcription Factors | 2011 |
DNA methylation patterns of Brachypodium distachyon chromosomes and their alteration by 5-azacytidine treatment.
Topics: 5-Methylcytosine; Azacitidine; Brachypodium; Chromosomes, Plant; Cloning, Molecular; DNA Methylation; Epigenomics; Genetic Loci; Genome, Plant; In Situ Hybridization, Fluorescence; Metaphase; Mitosis; Plant Immunity | 2011 |
Widespread existence of cytosine methylation in yeast DNA measured by gas chromatography/mass spectrometry.
Topics: 5-Methylcytosine; Azacitidine; DNA Methylation; DNA, Fungal; Gas Chromatography-Mass Spectrometry; Genome, Fungal; Reproducibility of Results; Species Specificity; Yeasts | 2012 |
Increased cleavage rate of human nuclear transfer embryos after 5-aza-2'-deoxycytidine treatment.
Topics: 5-Methylcytosine; Adult; Azacitidine; China; Decitabine; DNA Methylation; DNA Modification Methylases; Ectogenesis; Enzyme Inhibitors; Female; Fertilization in Vitro; Humans; Infertility; Kinetics; Male; Microscopy, Confocal; Microscopy, Fluorescence; Mitosis; Nuclear Transfer Techniques; Sperm Injections, Intracytoplasmic; Zygote | 2012 |
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; Cytidine; DNA Methylation; Humans; Liver Neoplasms; Male; Phenotype; Prostatic Neoplasms | 2013 |
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy.
Topics: 5-Methylcytosine; Azacitidine; Cell Hypoxia; Cytosine; Decitabine; DNA; DNA Modification Methylases; DNA-Binding Proteins; HeLa Cells; Humans; Single-Cell Analysis; Spectrometry, Fluorescence | 2013 |
Cytosine DNA methylation influences drug resistance in Escherichia coli through increased sugE expression.
Topics: 5-Methylcytosine; Azacitidine; Bacterial Proteins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ethidium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Membrane Proteins; Microbial Sensitivity Tests; Molecular Chaperones; Sigma Factor | 2014 |
A methylation status analysis of the apomixis-specific region in Paspalum spp. suggests an epigenetic control of parthenogenesis.
Topics: 5-Methylcytosine; Apomixis; Azacitidine; Chromosomes, Artificial, Bacterial; DNA Methylation; Epigenesis, Genetic; In Situ Hybridization, Fluorescence; Paspalum; Pollination; Polymorphism, Restriction Fragment Length | 2014 |
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2015 |
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine | 2015 |
NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs.
Topics: 5-Methylcytosine; Azacitidine; Cross-Linking Reagents; Cytoplasm; Enzyme Inhibitors; Golgi Apparatus; HEK293 Cells; HeLa Cells; Humans; In Vitro Techniques; Methylation; RNA, Transfer; tRNA Methyltransferases | 2015 |
Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC.
Topics: 5-Methylcytosine; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Computational Biology; Down-Regulation; Epigenesis, Genetic; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Tumor Escape | 2016 |
Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line, Tumor; Chromatography, Liquid; Decitabine; DNA; DNA Methylation; Humans; Limit of Detection; Linear Models; Methyltransferases; Mice; Mice, Nude; Reproducibility of Results; Tandem Mass Spectrometry | 2016 |
5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Cell Culture Techniques; Cytosine; DNA Methylation; DNA, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; Sequence Analysis; Transcriptome; Up-Regulation | 2016 |
Measurement of global DNA methylation levels by flow cytometry in mouse fibroblasts.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Proliferation; DNA Methylation; Embryo, Mammalian; Fibroblasts; Flow Cytometry; Mice, Inbred C57BL | 2017 |
Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; Dioxygenases; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Demethylation; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Small Interfering; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2017 |
The Yin-Yang Dynamics of DNA Methylation Is the Key Regulator for Smooth Muscle Cell Phenotype Switch and Vascular Remodeling.
Topics: 5-Methylcytosine; Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Azacitidine; Cell Dedifferentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Decitabine; Diet, High-Fat; Dioxygenases; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Inhibitors; Epigenesis, Genetic; Genetic Predisposition to Disease; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Proto-Oncogene Proteins; Rats; Signal Transduction; Time Factors; Trans-Activators; Vascular Remodeling | 2017 |
The effects of 5-azacytidine and cadmium on global 5-methylcytosine content and secondary metabolites in the freshwater microalgae Chlamydomonas reinhardtii and Scenedesmus quadricauda.
Topics: 5-Methylcytosine; Azacitidine; Cadmium; Chlamydomonas reinhardtii; Fresh Water; Microalgae; Scenedesmus | 2019 |
Methionine Supplementation Abolishes Nicotine-Induced Place Preference in Zebrafish: a Behavioral and Molecular Analysis.
Topics: 5-Methylcytosine; Animals; Azacitidine; Behavior, Animal; Brain; Choice Behavior; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Methionine; Nicotine; Phosphorylation; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reward; RNA, Messenger; Zebrafish; Zebrafish Proteins | 2021 |