Page last updated: 2024-08-22

5-methylchrysene and phenanthrenes

5-methylchrysene has been researched along with phenanthrenes in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199020 (95.24)18.7374
1990's1 (4.76)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hecht, SS; Hirota, N; Hoffmann, D; LaVole, E; Mazzarese, R; Ohmori, T1
Amin, S; Bedenko, V; Hecht, SS; Hoffmann, D; LaVoie, E; Mazzarese, R1
Amin, S; Hecht, SS; Hoffmann, D; LaVoie, E1
Hecht, SS; Hirota, N; Hoffmann, D; Loy, M1
Amin, S; Di Raddo, P; Harvey, RG; Hecht, SS1
Amin, S; el-Bayoumy, K; Hecht, SS1
Amin, S; Balanikas, G; Harvey, RG; Hecht, SS; Huie, K; Pataki, J1
Dipple, A; Harvey, RG; Hilton, BD; Pataki, J; Prakash, AS; Reardon, DB; Roman, JM1
el-Bayoumy, K; Hecht, SS; Shiue, GH1
Amin, S; Harvey, RG; Hecht, SS; Huie, K; Melikian, AA1
Bao, Z; Yang, SK1
Amin, S; Harvey, RG; Hecht, SS; Hoffmann, D; Huie, K; Melikian, AA; Pataki, J; Radok, L1
Amin, S; Harvey, RG; Hecht, SS; Hoffmann, D; Leszczynska, JM; Melikian, AA; Pataki, J1
Amin, S; Hecht, SS; Huie, K; Leszczynska, JM; Melikian, AA1
Amin, S; Glusker, JP; Harvey, RG; Hecht, SS; Kashino, S; Zacharias, DE1
Amin, S; Camanzo, J; Hecht, SS1
Harvey, RG; Lee, H; Pataki, J1
Hecht, SS; Hoffmann, D; LaVoie, EJ; Melikian, AA2
Amin, S; Furuya, K; Hecht, SS; Juchatz, A1
Hecht, SS; Hoffmann, D; Rivenson, A1

Other Studies

21 other study(ies) available for 5-methylchrysene and phenanthrenes

ArticleYear
Comparative mutagenicity, tumor-initiating activity, carcinogenicity, and in vitro metabolism of fluorinated 5-methylchrysenes.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:3

    Topics: Animals; Carcinogens; Chrysenes; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; In Vitro Techniques; Male; Mice; Microsomes, Liver; Mutagens; Neoplasms, Experimental; Phenanthrenes; Rats; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1979
1,2-dihydro-1,2-dihydroxy-5-methylchrysene, a major activated metabolite of the environmental carcinogen 5-methylchrysene.
    Cancer research, 1978, Volume: 38, Issue:7

    Topics: Animals; Chrysenes; In Vitro Techniques; Liver; Male; Mutagens; Mutation; Phenanthrenes; Rats; Rats, Inbred F344; Salmonella typhimurium

1978
Synthesis and mutagenicity of 5,11-dimethylchrysene and some methyl-oxidized derivatives of 5-methylchrysene.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:11

    Topics: Animals; Chrysenes; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Oxidation-Reduction; Phenanthrenes; Rats; Rats, Inbred F344; Salmonella typhimurium

1979
Tumor-initiating activity of fluorinated 5-methylchrysenes.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: Animals; Biotransformation; Chrysenes; Female; Mice; Neoplasms, Experimental; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1978
Comparative tumor initiating activities of cyclopentano and methyl derivatives of 5-methylchrysene and chrysene.
    Cancer letters, 1990, May-15, Volume: 51, Issue:1

    Topics: Animals; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Chrysenes; Female; Mice; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship

1990
Effects of 6-nitro substitution on 5-methylchrysene tumorigenicity, mutagenicity and metabolism.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Chrysenes; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mutagenicity Tests; Phenanthrenes; Rats; Rats, Inbred F344; Skin Neoplasms; Structure-Activity Relationship

1986
High stereoselectivity in mouse skin metabolic activation of methylchrysenes to tumorigenic dihydrodiols.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Chrysenes; Circular Dichroism; Female; Mice; Mutagenicity Tests; Phenanthrenes; Skin; Stereoisomerism

1987
Characterization of 5-methylchrysene-1,2-dihydrodiol-3,4-epoxide-DNA adducts.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Carcinogens; Chrysenes; Circular Dichroism; Deoxyguanosine; DNA; Magnetic Resonance Spectroscopy; Phenanthrenes; Stereoisomerism

1987
Comparative metabolism and DNA binding of 6-nitro-5-methylchrysene and 5-methylchrysene.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Animals; Carcinogens; Chrysenes; DNA; Female; Male; Mice; Phenanthrenes; Skin

1987
Enhancing effect of a bay region methyl group on tumorigenicity in newborn mice and mouse skin of enantiomeric bay region diol epoxides formed stereoselectively from methylchrysenes in mouse epidermis.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Animals, Newborn; Carcinogens; Chrysenes; Epoxy Compounds; Ethers, Cyclic; Methylation; Mice; Phenanthrenes; Skin; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship

1987
Two K-regions of 5-methylchrysene are sites of oxidative metabolism.
    Biochemical and biophysical research communications, 1986, Dec-15, Volume: 141, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Chrysenes; Circular Dichroism; Male; Microsomes, Liver; Oxidation-Reduction; Phenanthrenes; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism

1986
Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Animals; Animals, Newborn; Carcinogens; Chrysenes; Female; Male; Mice; Mice, Inbred ICR; Phenanthrenes; Sex Factors; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship

1985
Rates of hydrolysis and extents of DNA binding of 5-methylchrysene dihydrodiol epoxides.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Chromatography, High Pressure Liquid; Chrysenes; DNA; Epoxy Compounds; Ethers, Cyclic; Hydrolysis; Phenanthrenes

1985
Comparative metabolic activation in mouse skin of the weak carcinogen 6-methylchrysene and the strong carcinogen 5-methylchrysene.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Chrysenes; Mice; Phenanthrenes; Skin; Structure-Activity Relationship

1985
The bay-region geometry of some 5-methylchrysenes: steric effects in 5,6- and 5,12-dimethylchrysenes.
    Carcinogenesis, 1984, Volume: 5, Issue:11

    Topics: Carcinogens; Chrysenes; Molecular Conformation; Phenanthrenes; Structure-Activity Relationship

1984
Inhibition by a peri-fluorine atom of 1,2-dihydrodiol formation as a basis for the lower tumorigenicity of 12-fluoro-5-methylchrysene than of 5-methylchrysene.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Chrysenes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Phenanthrenes; Rats; Rats, Inbred F344; Structure-Activity Relationship; Tritium

1984
Carcinogenic metabolites of 5-methylchrysene.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Carcinogens; Chrysenes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Phenanthrenes; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1983
5-Methylchrysene metabolism in mouse epidermis in vivo, diol epoxide--DNA adduct persistence, and diol epoxide reactivity with DNA as potential factors influencing the predominance of 5-methylchrysene-1,2-diol-3,4-epoxide--DNA adducts in mouse epidermis.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Animals; Biotransformation; Carcinogens; Chrysenes; DNA; Epoxy Compounds; Ethers, Cyclic; Female; Kinetics; Mice; Mice, Inbred Strains; Phenanthrenes; Skin; Tritium

1983
Influence of bay-region methyl group on formation of 5-methylchrysene dihydrodiol epoxide:DNA adducts in mouse skin.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: Animals; Biotransformation; Carcinogens; Chrysenes; DNA; Epoxy Compounds; Female; Mice; Mice, Inbred Strains; Phenanthrenes; Skin

1982
Effects of fluorine substitution on the tumor initiating activity and metabolism of 5-hydroxymethylchrysene, a tumorigenic metabolite of 5-methylchrysene.
    Carcinogenesis, 1981, Volume: 2, Issue:10

    Topics: Animals; Carcinogens; Chrysenes; Female; Fluorine; In Vitro Techniques; Liver; Male; Mice; Neoplasms, Experimental; Phenanthrenes; Rats; Rats, Inbred F344; Structure-Activity Relationship; Subcellular Fractions; Time Factors

1981
Tumor-initiating activity of dihydrodiols formed metabolically from 5-methylchrysene.
    Cancer research, 1980, Volume: 40, Issue:5

    Topics: Animals; Biotransformation; Carcinogens; Carcinoma; Chrysenes; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Papilloma; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship

1980