5-methoxytryptamine and methiothepin

5-methoxytryptamine has been researched along with methiothepin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19909 (28.13)18.7374
1990's19 (59.38)18.2507
2000's3 (9.38)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Metcalf, MA1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J1
Adham, N; Bard, J; Branchek, TA; Durkin, M; Hartig, PR; Kao, HT; Olsen, M; Schecter, LE; Urquhart, D; Weinshank, RL1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Izzarelli, DG; Lewis-Higgins, L; Palmer, D; Parker, EM; Shapiro, RA1
Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Boess, FG; Monsma, FJ; Sleight, AJ1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T1
Glennon, RA1
Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T1
Lepailleur, A; Rochais, C; Thirumaran, SL1
Fernández-Guasti, A; Hong, E; López-Rubalcava, C1
Fernández-Guasti, A; López-Rubalcava, C1
Bom, AH; Den Boer, MO; Heiligers, JP; Saxena, PR; Villalón, CM1
Galzin, AM; Langer, SZ; Ramdine, R1
Blier, P; Chaput, Y; de Montigny, C; Steinberg, S1
Friedman, E; Wang, HY1
Galzin, AM; Langer, SZ; Moret, C; Verzier, B1
Blier, P; Galzin, AM; Langer, SZ1
Galzin, AM; Langer, SZ; Passarelli, F1
Hong, E; Villalon, CM1
Almeida, OF; Costa, T; Passarelli, F1
Göthert, M; Schlicker, E1
Bley, KR; Eglen, RM; Wong, EH1
Edvinsson, L; Jansen, I; Olesen, J1
Kojima, S; Shimo, Y1
De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM1
López Cabrera, M; Ramírez, JI; Sánchez, H; Velázquez Martínez, DN1

Reviews

2 review(s) available for 5-methoxytryptamine and methiothepin

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Structure-activity relationships of serotonin 5-HT
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship

2019

Other Studies

30 other study(ies) available for 5-methoxytryptamine and methiothepin

ArticleYear
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
    Molecular pharmacology, 1991, Volume: 40, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella

1991
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction

1993
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-15, Volume: 90, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Dose-Response Relationship, Drug; Gene Library; Guinea Pigs; Humans; Indoles; Lymphocytes; Molecular Sequence Data; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Serotonin; Serotonin Receptor Agonists; Spiperone; Sulfonamides; Sumatriptan; Tissue Distribution

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cloning, Molecular; COS Cells; DNA Primers; Ergolines; Glutamic Acid; Humans; Isoleucine; Kinetics; Ligands; Lysine; Models, Structural; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Serotonin; Transfection

1996
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents

1996
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
    Journal of neurochemistry, 1998, Volume: 71, Issue:5

    Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1998
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution

2001
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
    European journal of pharmacology, 2004, Jan-26, Volume: 484, Issue:2-3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine

2004
Species differences in the mechanism through which the serotonergic agonists indorenate and ipsapirone produce their anxiolytic action.
    Psychopharmacology, 1992, Volume: 107, Issue:1

    Topics: 5-Methoxytryptamine; Alprenolol; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Diazepam; Male; Methiothepin; Mice; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Species Specificity

1992
Evidence for the involvement of the 5-HT1A receptor in the anxiolytic action of indorenate and ipsapirone.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: 5-Methoxytryptamine; Alprenolol; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Diazepam; Exploratory Behavior; Male; Methiothepin; Mice; Motor Activity; Pindolol; Pyrimidines; Receptors, Serotonin; Serotonin

1990
Constriction of porcine arteriovenous anastomoses by indorenate is unrelated to 5-HT1A, 5-HT1B, 5-HT1C or 5-HT1D receptor subtypes.
    European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2

    Topics: 5-Methoxytryptamine; Anesthesia; Animals; Antihypertensive Agents; Arteriovenous Shunt, Surgical; Blood Pressure; Carotid Arteries; Heart Rate; Humans; In Vitro Techniques; Methiothepin; Microspheres; Muscle, Smooth, Vascular; Receptors, Serotonin; Regional Blood Flow; Swine; Vasoconstriction

1990
Phorbol-12,13-dibutyrate antagonizes while forskolin potentiates the presynaptic autoreceptor-mediated inhibition of [3H]-5-hydroxytryptamine release in rat hypothalamic slices.
    Synapse (New York, N.Y.), 1989, Volume: 3, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Drug Interactions; Drug Synergism; Electric Stimulation; Evoked Potentials; Hypothalamus; Indoles; Male; Methiothepin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Rats; Rats, Inbred Strains; Serotonin

1989
Electrophysiological assessment of putative antagonists of 5-hydroxytryptamine receptors: a single-cell study in the rat dorsal raphe nucleus.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:2

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Lysergic Acid Diethylamide; Male; Methiothepin; Neurons; Propranolol; Quinazolines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes

1989
Effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3H]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices.
    Journal of neurochemistry, 1988, Volume: 50, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Brain; Calcium; Chlorides; Fenfluramine; Hippocampus; Hypothalamus; Lithium; Lithium Chloride; Male; Methiothepin; Parietal Lobe; Potassium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1988
Interaction between tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors and the presynaptic 5-hydroxytryptamine inhibitory autoreceptors in the rat hypothalamus.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: 5-Methoxytryptamine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Citalopram; Electric Stimulation; Fenclonine; Hypothalamus; Imipramine; Lysergic Acid Diethylamide; Male; Methiothepin; Neurotransmitter Agents; Pargyline; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1985
Diurnal variation in the function of serotonin terminals in the rat hypothalamus.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: 5-Methoxytryptamine; Animals; Carrier Proteins; Circadian Rhythm; Citalopram; Electric Stimulation; Fenfluramine; Hypothalamus; Indoles; Male; Methiothepin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1989
Interaction between neuronal uptake inhibitors and presynaptic serotonin autoreceptors in rat hypothalamic slices: comparison of K+ and electrical depolarization.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Citalopram; Electric Stimulation; Fenclonine; Hypothalamus; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Methiothepin; Neurotransmitter Uptake Inhibitors; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sodium

1987
External carotid vasodilation induced by serotonin and indorenate.
    Proceedings of the Western Pharmacology Society, 1988, Volume: 31

    Topics: 5-Methoxytryptamine; Animals; Carotid Artery, External; Dogs; Female; Male; Methiothepin; Reference Values; Regional Blood Flow; Serotonin; Vasodilation

1988
Pertussis toxin inactivates the presynaptic serotonin autoreceptor in the hippocampus.
    European journal of pharmacology, 1988, Oct-18, Volume: 155, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Hippocampus; In Vitro Techniques; Lysergic Acid Diethylamide; Methiothepin; Pertussis Toxin; Potassium; Rats; Receptors, Serotonin; Serotonin; Virulence Factors, Bordetella

1988
Autoreceptor-mediated inhibition of 3H-5-hydroxytryptamine release from rat brain cortex slices by analogues of 5-hydroxytryptamine.
    Life sciences, 1983, Mar-14, Volume: 32, Issue:11

    Topics: 5-Methoxytryptamine; Animals; Cerebral Cortex; Dihydroxytryptamines; Dose-Response Relationship, Drug; Male; Methiothepin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Tryptamines

1983
Characterization of 5-hydroxytryptamine-induced depolarizations in rat isolated vagus nerve.
    European journal of pharmacology, 1994, Aug-01, Volume: 260, Issue:2-3

    Topics: 5-Methoxytryptamine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electrophysiology; Granisetron; In Vitro Techniques; Indoles; Male; Methiothepin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Regression Analysis; Serotonin; Serotonin Antagonists; Sulfonamides; Temperature; Vagus Nerve

1994
5-Hydroxytryptamine receptor characterization of human cerebral, middle meningeal and temporal arteries: regional differences.
    Acta physiologica Scandinavica, 1993, Volume: 147, Issue:2

    Topics: 5-Methoxytryptamine; Cerebral Arteries; Humans; Indoles; Ketanserin; Meningeal Arteries; Methiothepin; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Temporal Arteries; Vasoconstriction; Vasoconstrictor Agents

1993
Investigation into the 5-hydroxytryptamine-induced atropine-resistant neurogenic contraction of guinea-pig proximal colon.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: 5-Methoxytryptamine; Animals; Atropine; Colon; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Indoles; Male; Methiothepin; Muscarinic Antagonists; Muscle Contraction; Ondansetron; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Nature of 5-HT1-like receptors mediating depressor responses in vagosympathectomized rats; close resemblance to the cloned 5-ht7 receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: 5-Methoxytryptamine; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Ergolines; Heart Rate; Isoproterenol; Lisuride; Male; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy

1997
Evidence that methiothepin enhances the anorectic effect of indorenate.
    Proceedings of the Western Pharmacology Society, 1998, Volume: 41

    Topics: 5-Methoxytryptamine; Animals; Drinking; Drug Synergism; Eating; Male; Methiothepin; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists

1998