5-methoxytryptamine has been researched along with melatonin in 144 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (40.97) | 18.7374 |
| 1990's | 42 (29.17) | 18.2507 |
| 2000's | 21 (14.58) | 29.6817 |
| 2010's | 16 (11.11) | 24.3611 |
| 2020's | 6 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Cunha, AC; Ferreira, VF; Garcia, CR; Jordão, AK; Nakabashi, M; Schuck, DC | 1 |
| Boersma, YL; Dekker, FJ; Dömling, ASS; Eleftheriadis, N; Wójcik, M; Zwinderman, MRH | 1 |
| Andrade, RB; Bougie, D; Boxer, MB; Brimacombe, KR; Brown, LE; Brown, MK; Burns, NZ; Cha, JK; Cheff, DM; Cheng, K; Clardy, J; Clement, JA; Coussens, NP; Crooks, PA; Cuny, GD; Dillon, C; Dorjsuren, D; Eastman, RT; Ganor, J; Garg, NK; Goess, BC; Grossman, RB; Guha, R; Hall, MD; Henderson, MJ; Huang, R; Hughes, CC; Iannotti, MJ; Inglese, J; Itkin, Z; Jadhav, A; Johnston, JN; Joullie, MM; Karavadhi, S; Kearney, SE; Kinghorn, AD; Kingston, DGI; Klumpp-Thomas, C; Krische, MJ; Kwon, O; Lee, TD; Lynch, C; Maimone, TJ; Majumdar, S; Maloney, KN; Mevers, EE; Michael, S; Mohamed, E; Moreno, J; Morrill, LA; Murphy, BT; Nagorny, P; Olson, DE; Overman, LE; Picazo, E; Porco, JA; Ren, T; Rivas, F; Rohde, JM; Ross, SA; Roth, JS; Sakamuru, S; Sarpong, R; Sharma, I; Shaw, JT; Shen, B; Shen, M; Shi, W; Shinn, P; Simeonov, A; Snyder, JK; Stephenson, CRJ; Sun, W; Susick, RB; Tan, DS; Tang, Y; Taylor, RE; Thomson, RJ; Titus, SA; Verano, AL; Vosburg, DA; Wan, KK; Wu, J; Wuest, WM; Xia, M; Xu, Z; Yasgar, A; Zahoránszky-Kőhalmi, G; Zakarian, A; Zhang, Y; Zhang, YQ; Zhao, J; Zhao, T; Zheng, W; Zuo, Z | 1 |
| de Leiva, A; Schwartz, S | 1 |
| Cardinali, DP; Prevedello, MR; Ritta, MN | 1 |
| Aghajanian, GK; Rogawski, MA; Roth, RH | 1 |
| Engel, JN; Klein, DC; Martin, JE | 1 |
| Brandstater, JF; Lazarus, L; Smythe, GA | 1 |
| Levine, L; Riceberg, LJ | 1 |
| Kvetnoĭ, IM; Raĭkhlin, NT | 1 |
| Anis, Y; Zisapel, N | 1 |
| Anisimov, VN; Bondarenko, LA | 1 |
| Pévet, P; Raynaud, F | 3 |
| Kehajova, J; Persengiev, S | 1 |
| Balzer, I; Hardeland, R | 1 |
| Masson-Pévet, M; Pévet, P; Raynaud, F; Vivien-Roels, B | 1 |
| Masson-Pévet, M; Pévet, P | 1 |
| Buzzell, GR; McNeill, ME; Menendez-Pelaez, A; Reiter, RJ; Troiani, ME | 1 |
| Blazynski, C; Cohen, AI; Ferrendelli, JA | 1 |
| Malakhova, NV; Raushenbakh, MO; Romanenko, VI; Sergeeva, TI; Suvorov, NN | 1 |
| Airaksinen, MM; Leino, M | 1 |
| Bondarenko, L; Rom-Bugoslavskaja, ES | 1 |
| Eon, MT; Esnaud, H; Galzin, AM; Langer, SZ; Lee, CR; Pévet, P | 1 |
| Morton, DJ | 1 |
| Ng, TB; Ooi, VE | 1 |
| Kelly, RW; Lincoln, GA | 1 |
| Migliaccio, S; Nordio, M; Reiter, RJ; van Jaarsveld, A; Vaughan, MK; Zisapel, N | 1 |
| Alexander, H; Manz, B; Pollow, K; Seidel, A; Vollrath, L; Wagner, B; Wiedemann, K; Zimmermann, G | 1 |
| Chantegrel, J; Claustrat, B; Luu-Duc, C; Marsura, A; Masson-Pévet, M; Pévet, P | 1 |
| Ghosh, M; Haldar, C | 2 |
| Masson-Pévet, M; Miguel, JL; Pévet, P; Raynaud, F; Vivien-Roels, B | 1 |
| Hill, BT; Shellard, SA; Whelan, RD | 1 |
| Laudon, M; Yaron, Z; Zisapel, N | 1 |
| Ng, TB | 1 |
| Abou Samra, AB; Bertrand, J; Durand, A; Fèvre-Montange, M; Loras, B; Tourniaire, J | 1 |
| Balemans, MG; de Koning, J; Ebels, I; van Benthem, J | 1 |
| Cardinali, DP; Franchi, AM; Gimeno, MF; Vacas, MI | 1 |
| Rom-Buguslavskaia, ES; Shcherbakova, VS | 1 |
| Amador, AG; Bartke, A; Klemcke, HG; Reiter, RJ; Steger, RW; Vaughn, MK | 1 |
| Haldar, C; Pandey, R | 1 |
| Mirmiran, M; Pévet, P | 1 |
| Blask, DE; Hill, SM | 1 |
| Masson-Pévet, M; Pévet, P; Vivien-Roels, B | 1 |
| Laudon, M; Zisapel, N | 1 |
| Nayak, PK; Singh, TP | 1 |
| Buijs, RM; Masson-Pévet, M; Pévet, P | 1 |
| Balemans, MG; Ebels, I; Mans, DR; van Benthem, J | 1 |
| Aubert, ML; Lang, U; Rivest, RW; Sizonenko, PC; Vinas-Bradtke, JC | 1 |
| Kohsaka, M; Mori, A; Takeuchi, H | 1 |
| Pévet, P | 1 |
| Balemans, MG; de Reuver, GF; Pévet, P | 1 |
| Beck, O; Jonsson, G; Lundman, A | 1 |
| Balemans, MG; Ebels, I; Hendriks, HG; van Berlo, MF | 1 |
| Haldar-Misra, C; Pévet, P | 2 |
| Balemans, MG; Flight, WF; Mans, D | 1 |
| Smith, I | 1 |
| Cardinali, DP; Keller Sarmiento, MI; Vacas, MI | 1 |
| Collin, JP; Juillard, MT; Voisin, P | 1 |
| Champney, TH; Holtorf, AP; Petterborg, LJ; Reiter, RJ; Richardson, BA; Vaughan, GM; Vaughan, MK | 1 |
| Heth, G; Hiam, A; Nevo, E; Pevet, P | 1 |
| Champney, TH; Holtorf, A; Reiter, RJ; Vaughan, MK | 1 |
| Balemans, MG; Bary, FA; Legerstee, WC; Van Benthem, J | 1 |
| Beck, O; Jonsson, G | 1 |
| Beck, O; Borg, S; Lundman, A | 1 |
| Delaage, MA; Geffard, MR; Puizillout, JJ | 1 |
| Al-Dujaili, EA; Boscaro, M; Edwards, CR | 1 |
| Rollag, MD | 1 |
| Gan, J; Iuvone, PM | 1 |
| Besharse, JC; Grace, MS | 1 |
| Chan, WY; Ng, TB | 4 |
| Ekström, P; Grossmann, E; Meissl, H; Yáñez, J | 1 |
| Havouis, R; Khan, NA; Moulinoux, JP; Querné, D; Rault, B; Shacoori, V | 1 |
| Meissl, H; Yáñez, J | 2 |
| Anis, Y; Nir, I; Oaknin-Bendahan, S; Zisapel, N | 1 |
| Balzer, I; Behrmann, G; Fuhrberg, B; Hardeland, R; Meyer, TJ; Poeggeler, B; Reiter, RJ; Uría, H; Wolf, R | 1 |
| Blickenstaff, RT; Reddy, S; Witt, R | 1 |
| Alonso-Gómez, AL; Gan, J; Iuvone, PM | 1 |
| Haldar, C | 2 |
| Behnke, B; Koopmann, K; Krone, W; Müller-Wieland, D | 1 |
| Liu, WK; Ng, TB; Sze, SF | 1 |
| Blickenstaff, RT; Brandstadter, SM; Reddy, S; Witt, R | 1 |
| Chong, NW; Evans, JE; Sugden, D | 1 |
| Pruski, D; Slominski, A | 1 |
| Kanchev, L; Kehayov, I; Konakchieva, R; Kyurkchiev, S; Taushanova, P | 1 |
| Baker, J; Ermak, G; Gaudet, SJ; Grande, M; Guisti, LW; Rosano, TG; Slominski, A | 1 |
| Behrmann, G; Burkhardt, S; Fuhrberg, B; Hardeland, R; Meyer, TJ; Poeggeler, B; Uría, H | 1 |
| Behrmann, G; Burkhardt, S; Fuhrberg, B; Hardeland, R; Obst, B; Poeggeler, B; Uria, H | 1 |
| Tslm, ST; Wong, JT; Wong, YH | 1 |
| Tsim, ST; Wong, JT; Wong, YH | 1 |
| Li, P; Pang, SF; Tsang, CW | 1 |
| Saxena, N | 1 |
| Garratt, PJ; Pickering, H; Sugden, D; Teh, MT | 1 |
| Lee, DW; Ng, TB; Ooi, VE | 1 |
| Ng, TB; Wang, H | 1 |
| Antolín, I; Burkhardt, S; Coto-Montes, A; Fuhrberg, B; Hardeland, R | 1 |
| de Rossi, RH; Galian, RE; Veglia, AV | 1 |
| Liu, F; Ng, TB | 1 |
| Lissoni, P | 1 |
| Bonfanti, A; Bucovec, R; Fumagalli, L; Giani, L; Lissoni, P; Mandelli, A; Roselli, MG; Rovelli, F | 1 |
| Fung, MC; Liu, F; Ng, TB | 1 |
| Bondarenko, LA; Gubina-Vakulik, GI | 1 |
| Sugden, D; Teh, MT | 1 |
| Bick, R; Bryant-Thomas, T; Chyan, YJ; Cruz-Sanchez, F; Dubocovich, M; Pappolla, MA; Perry, G; Poeggeler, B; Simovich, MJ; Smith, MA | 1 |
| Burkhardt, S; Dose, A; Hardeland, R; Poeggeler, B; Schoenke, M; Thuermann, S | 1 |
| Bertolucci, C; Brandstätter, R; Foà, A; Gwinner, E; Wagner, G | 1 |
| Bayari, S; Ide, S | 1 |
| Kauser, S; Pisarchik, A; Slominski, A; Tobin, DJ; Wortsman, J; Zbytek, B | 1 |
| KVEDER, S; McISAAC, WM | 1 |
| Hernández, A; Mondaca, M; Noseda, R; Sierralta, W; Soto-Moyano, R; Valladares, L | 1 |
| El-Sherif, Y; Hogan, MV; Li, PK; Tesoriero, J; Wieraszko, A; Witt-Enderby, P | 1 |
| Robertson, AD; Willis, GL | 2 |
| Ceinos, RM; Míguez, JM; Rábade, S; Soengas, JL | 1 |
| Willis, GL | 1 |
| Hosoya, K; Kaya, K; Kubo, T; Nomachi, M | 1 |
| Catalá, A; Fagali, N | 2 |
| Prendergast, BJ | 1 |
| Dong, S; Jin, Q; Li, M; Wang, J; Wang, L | 1 |
| Lissoni, P; Rovelli, F | 1 |
| Lissoni, P; Messina, G; Rovelli, F | 1 |
| Fischer, TW; Janjetovic, Z; Kim, TK; Kleszczynski, K; Li, W; Lin, Z; Reiter, RJ; Slominski, AT; Sweatman, T | 1 |
| Kim, TK; Li, W; Lin, Z; Slominski, AT; Tidwell, WJ | 1 |
| Bromek, E; Daniel, WA; Gołembiowska, K; Haduch, A; Wójcikowski, J | 1 |
| Alatorre-Jimenez, MA; Back, K; Hardeland, R; Manchester, LC; Reiter, RJ; Tan, DX | 1 |
| Fan, F; Li, D; Lu, L; Sun, Z; Tang, W; Tian, Z; Zhang, J; Zhou, Z | 1 |
| Antolín, I; Branco-Santos, J; Herrera, F; Letra-Vilela, R; Martin, V; Outeiro, TF; Puente-Moncada, N; Rocha, AM; Rodriguez, C; Sánchez-Sánchez, AM; Santa-Marta, M | 1 |
| Back, K; Choi, GH; Lee, HY | 1 |
| Cai, WJ; Feng, YQ; Wu, Y; Ye, T; Yin, X; Yu, L; Zheng, SJ | 1 |
| Ahammed, GJ; Wang, K; Xing, Q; Zhou, J | 1 |
| Hanuszewska-Dominiak, M; Lewczuk, B; Martyniuk, K | 1 |
| Boutin, JA; Legros, C; Yous, S | 1 |
| Boutin, JA; Dupuis, P; Ferry, G; Legros, C | 1 |
| Boutin, JA; Calamini, B; Ferry, G | 1 |
| Brożyna, AA; Foksiński, M; Gagat, M; Kleszczyński, K; Linowiecka, K; Möller, JKS; Pyza, E; Reiter, RJ; Slominski, AT; Steinbrink, K; Tulic, MK; Wolnicka-Glubisz, A | 1 |
7 review(s) available for 5-methoxytryptamine and melatonin
| Article | Year |
|---|---|
Methoxyindoles of the retina.
Topics: 5-Methoxytryptamine; Animals; Carbolines; Circadian Rhythm; Humans; Hydroxyindoleacetic Acid; Indoles; Melatonin; Neurotransmitter Agents; Photic Stimulation; Pineal Gland; Rabbits; Retina; Serotonin; Tryptophan | 1985 |
Is 5-methoxytryptamine a pineal hormone?
Topics: 5-Methoxytryptamine; Animals; Cats; Dogs; Female; Humans; Male; Melatonin; Neurotransmitter Agents; Organ Size; Ovary; Pineal Gland; Rabbits; Rats; Rats, Inbred Strains; Reproduction; Sheep; Swine; Testis; Tryptamines | 1983 |
Indoles of pineal origin: biochemical and physiological status.
Topics: 5-Methoxytryptamine; Animals; Brain; Cattle; Chemical Phenomena; Chemistry; Circadian Rhythm; Humans; Indoles; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Sheep; Swine; Tryptamines | 1983 |
The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease.
Topics: 5-Methoxytryptamine; Animals; Antiparkinson Agents; Disease Models, Animal; Humans; Levodopa; Melatonin; Parkinson Disease | 2005 |
Principles of psychoneuroendocrinoimmunotherapy of cancer.
Topics: 5-Methoxytryptamine; Antineoplastic Combined Chemotherapy Protocols; Cannabinoid Receptor Modulators; Humans; Immunotherapy; Interleukin-2; Melatonin; Naltrexone; Neoplasms; Neurosecretory Systems | 2012 |
On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species.
Topics: 5-Methoxytryptamine; Acetylation; Animals; Bacteria; Humans; Melatonin; Methylation; Plants; Species Specificity; Yeasts | 2016 |
Functions and prospects of melatonin in plant growth, yield, and quality.
Topics: 5-Methoxytryptamine; Animals; Crops, Agricultural; Free Radicals; Melatonin; Plant Physiological Phenomena | 2022 |
4 trial(s) available for 5-methoxytryptamine and melatonin
| Article | Year |
|---|---|
Modulation of anticancer cytokines IL-2 and IL-12 by melatonin and the other pineal indoles 5-methoxytryptamine and 5-methoxytryptophol in the treatment of human neoplasms.
Topics: 5-Methoxytryptamine; Antineoplastic Combined Chemotherapy Protocols; Humans; Immunotherapy; Indoles; Interleukin-12; Interleukin-2; Melatonin; Neoplasm Metastasis; Neoplasms; Neuroimmunomodulation; Treatment Outcome | 2000 |
Thrombopoietic properties of 5-methoxytryptamine plus melatonin versus melatonin alone in the treatment of cancer-related thrombocytopenia.
Topics: 5-Methoxytryptamine; Adult; Aged; Blood Platelets; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Male; Melatonin; Middle Aged; Neoplasms; Platelet Count; Thrombocytopenia | 2001 |
Recovery from experimental Parkinson's disease in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride treated marmoset with the melatonin analogue ML-23.
Topics: 5-Methoxytryptamine; Animals; Behavior, Animal; Callithrix; Cross-Over Studies; Eating; Male; Melatonin; Parkinsonian Disorders; Reaction Time; Recovery of Function | 2005 |
Cancer as the main aging factor for humans: the fundamental role of 5-methoxy-tryptamine in reversal of cancer-induced aging processes in metabolic and immune reactions by non-melatonin pineal hormones.
Topics: 5-Methoxytryptamine; Administration, Oral; Age Factors; Aging; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Drug Administration Schedule; Female; Humans; Male; Melatonin; Neoplasms; Pineal Gland; Platelet Count; Retrospective Studies; Thrombocytopenia; Thrombopoiesis; Time Factors; Treatment Outcome | 2012 |
133 other study(ies) available for 5-methoxytryptamine and melatonin
| Article | Year |
|---|---|
Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum.
Topics: Antimalarials; Cell Cycle; Dose-Response Relationship, Drug; Indoles; Melatonin; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2014 |
Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Topics: | 2018 |
Relation of pH to fluorescence of serotonin, melatonin, and other indole compounds reacted with o-phthaldialdehyde.
Topics: 5-Methoxytryptamine; Aldehydes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Hot Temperature; Hydrogen-Ion Concentration; Indoles; Light; Melatonin; o-Phthalaldehyde; Serotonin; Spectrometry, Fluorescence; Time Factors; Toluene | 1976 |
Fast axonal transport in rat sciatic nerve. Inhibition by pineal indoles.
Topics: 5-Methoxytryptamine; Animals; Axonal Transport; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Male; Melatonin; Nerve Tissue Proteins; Pentoxifylline; Peripheral Nerves; Pineal Gland; Rats; Serotonin | 1979 |
Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase.
Topics: 5-Methoxytryptamine; Amidohydrolases; Anilides; Animals; Hypothalamus; In Vitro Techniques; Kinetics; Liver; Male; Melatonin; Organ Specificity; Pargyline; Rats; Tryptamines | 1979 |
Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin, and 5-methoxytryptamine.
Topics: 5-Methoxytryptamine; Age Factors; Animals; Gonadotropin-Releasing Hormone; In Vitro Techniques; Indoles; Luteinizing Hormone; Melatonin; Pituitary Gland; Rats; Rats, Inbred Strains; Secretory Rate; Serotonin | 1977 |
Serotoninergic control of rat growth hormone secretion.
Topics: 5-Methoxytryptamine; Animals; Cyproheptadine; Dimethoxyphenylethylamine; Female; Growth Hormone; Handling, Psychological; Male; Melatonin; Pentobarbital; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Serotonin; Sex Factors | 1975 |
Radioimmunoassay for melatonin.
Topics: 5-Methoxytryptamine; Animals; Antigen-Antibody Reactions; Humans; Immunization; Immunoglobulin G; Indoles; Indomethacin; Melatonin; Methods; Rabbits; Radioimmunoassay; Serum Albumin | 1975 |
[Biosynthesis of 5- methoxy-N-acetyltryptamine (melatonin) in enterochromaffin cells].
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Chromaffin System; Chromatography, Thin Layer; Enterochromaffin Cells; Melatonin; Rabbits; Serotonin; Tryptamines | 1976 |
Affinity labeling of melatonin binding sites in the hamster brain.
Topics: 5-Methoxytryptamine; Animals; Binding, Competitive; Brain; Cricetinae; Kinetics; Male; Melatonin; Mesocricetus; Receptors, Melatonin; Receptors, Neurotransmitter; Synaptosomes | 1991 |
[Effects of an epiphyseal peptide preparation epithalamin on serotonin metabolism in the pineal gland of rats].
Topics: 5-Methoxytryptamine; Animals; Cattle; Hydroxyindoleacetic Acid; Male; Melatonin; Peptides; Pineal Gland; Rats; Serotonin; Time Factors | 1990 |
Determination of 5-methoxyindoles in pineal gland and plasma samples by high-performance liquid chromatography with electrochemical detection.
Topics: 5-Methoxytryptamine; Animals; Antioxidants; Buffers; Chromatography, High Pressure Liquid; Cricetinae; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Indoles; Light; Male; Melatonin; Mesocricetus; Pineal Gland | 1991 |
Inhibitory action of melatonin and structurally related compounds on testosterone production by mouse Leydig cells in vitro.
Topics: 5-Methoxytryptamine; Animals; Dose-Response Relationship, Drug; Indoles; Leydig Cells; Male; Melatonin; Mice; Mice, Inbred BALB C; Testosterone | 1991 |
Photoperiodism and effects of indoleamines in a unicellular alga, Gonyaulax polyedra.
Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Dinoflagellida; Light; Melatonin; Periodicity; Temperature | 1991 |
Low ambient temperature does not affect the pineal concentrations of either 5-methoxytryptamine or melatonin in golden hamsters kept under short photoperiod.
Topics: 5-Methoxytryptamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Cold Temperature; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Organ Size; Pineal Gland; Temperature; Testis | 1991 |
Effect of different photoperiods on the diurnal rhythm of 5-methoxytryptamine in the pineal gland of golden hamsters (Mesocricetus auratus).
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Cricetinae; Gene Expression Regulation; Light; Male; Melatonin; Mesocricetus; Pargyline; Pineal Gland; Sexual Behavior, Animal; Stimulation, Chemical | 1991 |
Plasma concentrations of 5-methoxytryptamine, 5-methoxytryptophol and melatonin after 5-methoxytryptamine administration of golden hamsters: physiological implications.
Topics: 5-Methoxytryptamine; Animals; Atrophy; Circadian Rhythm; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Pineal Gland; Testis | 1991 |
"Synaptic" ribbons and spherules lacking in the pineal gland of the European hamster appear after ganglionectomy.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Cricetinae; Ganglionectomy; Male; Melatonin; Microscopy, Electron; Pineal Gland; Sexual Behavior, Animal | 1990 |
Effects of short-day photoperiods and of N-(2,4-dinitrophenyl)-5-methoxytryptamine, a putative melatonin antagonist, on melatonin synthesis in the Harderian gland of the Syrian hamster, Mesocricetus auratus.
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Acetyltransferases; Analysis of Variance; Animals; Cricetinae; Female; Harderian Gland; Lacrimal Apparatus; Lighting; Male; Melatonin; Mesocricetus; Periodicity | 1990 |
Indoleamine-sensitive adenylate cyclase in rabbit retina: characterization and distribution.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Adenylyl Cyclases; Animals; Cats; Cyclic AMP; Cyclic GMP; Guanosine Triphosphate; Haloperidol; Humans; Melatonin; Methoxydimethyltryptamines; Rabbits; Retina; Serotonin; Serotonin Antagonists; Tryptamines | 1985 |
[Blastomogenic activity of biogenic methoxyindoles].
Topics: 5-Methoxytryptamine; Animals; Hydroxyindoleacetic Acid; Melatonin; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Tryptamines | 1985 |
Seasonal peculiarities of thyroxine influence on the way of serotonin metabolism in the pineal gland of the rat.
Topics: 5-Methoxytryptamine; Animals; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Seasons; Serotonin; Thyroxine | 1987 |
Day-night rhythm of 5-methoxytryptamine biosynthesis in the pineal gland of the golden hamster (Mesocricetus auratus).
Topics: 5-Methoxytryptamine; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Cricetinae; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mesocricetus; Pineal Gland; Serotonin | 1988 |
Effect of methoxyindole administration on plasma cation levels in the rat.
Topics: 5-Methoxytryptamine; Animals; Cations; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Hydroxyindoleacetic Acid; Indoles; Magnesium; Melatonin; Rats; Rats, Inbred Strains; Tryptophan; Zinc | 1989 |
Histological studies on the effects of pineal 5-methoxyindoles on the reproductive organs of the male golden hamster.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Hydroxyindoleacetic Acid; Indoles; Leydig Cells; Male; Melatonin; Mesocricetus; Pineal Gland; Seminal Vesicles; Testis | 1989 |
Test of ML23 as an antagonist to the effects of melatonin in the ram.
Topics: 5-Methoxytryptamine; Animals; Follicle Stimulating Hormone; Light; Lysine; Male; Melatonin; Reproduction; Serotonin; Testis; Testosterone | 1989 |
A novel melatonin antagonist, N-(2,4-dinitrophenyl)-5-methoxytryptamine neutralizes some effects of melatonin in the female Syrian hamster.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Melatonin; Mesocricetus; Organ Size; Ovary; Pituitary Gland; Progesterone; Prolactin; Serotonin; Thyroxine; Triiodothyronine; Uterus | 1989 |
Development and validation of a radioimmunoassay for serum melatonin.
Topics: 5-Methoxytryptamine; Animals; Antibody Formation; Cricetinae; Evaluation Studies as Topic; Female; Humans; Immune Sera; Iodine; Male; Melatonin; Mesocricetus; Radioimmunoassay; Rats; Rats, Inbred Strains; Reference Standards | 1989 |
Failure of N-(2,4-dinitrophenyl)-5-methoxytryptamine (a putative melatonin antagonist) and of N-(3,5-dinitrophenyl)-5-methoxytryptamine to prevent the effects of injections of melatonin in the late afternoon on testicular activity of the golden hamster.
Topics: 5-Methoxytryptamine; Animals; Atrophy; Cold Temperature; Cricetinae; Light; Male; Melatonin; Mesocricetus; Serotonin; Testis | 1989 |
Effect of pinealectomy and 5-methoxyindoles on Harderian gland activity of the Indian Jungle bush quail Perdicula asiatica.
Topics: 5-Methoxytryptamine; Animals; Harderian Gland; Indoles; Lacrimal Apparatus; Male; Melatonin; Pineal Gland; Quail; Seasons; Serotonin | 1989 |
The effect of 5-methoxytryptamine on golden hamster gonads is not a consequence of its acetylation into melatonin.
Topics: 5-Methoxytryptamine; Acetylation; Animals; Atrophy; Cricetinae; Light; Male; Melatonin; Mesocricetus; Organ Size; Serotonin; Testis | 1989 |
Growth inhibitory and cytotoxic effects of melatonin and its metabolites on human tumour cell lines in vitro.
Topics: 5-Methoxytryptamine; 5,6-Dihydroxytryptamine; Cell Line; Drug Screening Assays, Antitumor; Humans; Melatonin; Serotonin; Tryptamines; Tumor Cells, Cultured | 1989 |
N-(2,4-dinitrophenyl)-5-methoxytryptamine, a novel melatonin antagonist: effects on sexual maturation of the male and female rat and on oestrous cycles of the female rat [corrected].
Topics: 5-Methoxytryptamine; Administration, Oral; Animals; Estrus; Female; Male; Melatonin; Ovulation; Rats; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin; Sexual Maturation; Tryptamines | 1988 |
Effects of pineal indoles on corticosterone and aldosterone production by isolated rat adrenal cells.
Topics: 5-Methoxytryptamine; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dose-Response Relationship, Drug; In Vitro Techniques; Melatonin; Pineal Gland; Rats; Tryptamines; Vasotocin | 1987 |
Effect of indolamines on beta-endorphin release by rat anterior pituitary cells.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Creatinine; Drug Combinations; Endorphins; Hydroxytryptophol; In Vitro Techniques; Indoles; Male; Melatonin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1985 |
The effect of different photoperiods on the methylating capacity of the pineal gland of adult, male golden hamsters, with special reference to 5-methoxyindoles.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Follicle Stimulating Hormone; Indoles; Light; Luteinizing Hormone; Male; Melatonin; Mesocricetus; Periodicity; Pineal Gland; Testis; Tryptophan | 1986 |
Melatonin, 5-methoxytryptamine and some of their analogs as cyclo-oxygenase inhibitors in rat medial basal hypothalamus.
Topics: 5-Methoxytryptamine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Hypothalamus, Middle; In Vitro Techniques; Male; Melatonin; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains; Tryptamines | 1987 |
[Epiphysis cerebri-thyroid interrelations. Distorting effect of partial thyroidectomy on the antithyroid action of epiphyseal methoxyindoles in animal experiments].
Topics: 5-Methoxytryptamine; Animals; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Hormones; Thyroidectomy; Thyrotropin; Tryptamines | 1988 |
Effects of pinealectomy and melatonin or 5-methoxytryptamine on testicular LH and PRL receptors in Syrian hamsters (Mesocricetus auratus).
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Pineal Gland; Receptors, LH; Receptors, Prolactin; Serotonin; Testis | 1988 |
Effect of melatonin and 5-methoxytryptamine administration on the testis and pineal gland activity of the fresh-water snake, Natrix piscator.
Topics: 5-Methoxytryptamine; Animals; Drug Implants; Injections, Subcutaneous; Male; Melatonin; Pineal Gland; Serotonin; Snakes; Testis | 1988 |
Effect of 5-methoxyindoles on testicular function of the Indian jungle bush quail Perdicula asiatica.
Topics: 5-Methoxytryptamine; Animals; Drug Implants; Indoles; Injections, Subcutaneous; Male; Melatonin; Organ Size; Pineal Gland; Quail; Serotonin; Testis; Vas Deferens | 1988 |
Effects of melatonin and 5-methoxytryptamine on sleep-wake patterns in the male rat.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Drug Implants; Electroencephalography; Electromyography; Male; Melatonin; Rats; Sleep; Sleep, REM; Tryptamines; Wakefulness | 1986 |
Effects of melatonin on cancer: studies on MCF-7 human breast cancer cells in culture.
Topics: 5-Methoxytryptamine; Breast Neoplasms; Cell Division; Cell Line; Estradiol; Female; Humans; Kinetics; Melatonin; Prolactin; Serotonin | 1986 |
Pinealectomy and constant release of melatonin or 5-methoxytryptamine induce testicular atrophy in the European hamster (Cricetus cricetus, L.).
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Male; Melatonin; Mesocricetus; Organ Size; Pineal Gland; Seasons; Species Specificity; Testis; Tryptamines | 1987 |
A novel melatonin antagonist affects melatonin-mediated processes in vitro and in vivo.
Topics: 5-Methoxytryptamine; Animals; Dopamine; Electric Stimulation; Female; Genitalia, Male; Hypothalamus; Male; Melatonin; Rats; Tryptamines | 1987 |
Effect of melatonin and 5-methoxytryptamine on sex steroids and thyroid hormones during the prespawning phase of the annual reproductive cycle in the freshwater teleost, Clarias batrachus.
Topics: 17-alpha-Hydroxyprogesterone; 5-Methoxytryptamine; Animals; Catfishes; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Male; Melatonin; Radioimmunoassay; Reproduction; Testosterone; Thyroid Hormones; Thyroxine; Triiodothyronine; Tryptamines | 1987 |
Effect of pinealectomy and a constant high level of circulating melatonin or of 5-methoxytryptamine on the vasopressinergic innervation in the brain of the European hamster (Cricetus cricetus, L).
Topics: 5-Methoxytryptamine; Animals; Body Weight; Brain; Cricetinae; Male; Melatonin; Organ Size; Pineal Gland; Testis; Tryptamines; Vasopressins | 1987 |
Rhythmic synthesis of various 5-methoxyindoles in the pineal gland of male adult golden hamsters, kept under the same artificial conditions throughout the year.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Pineal Gland; Seasons; Tryptophan | 1985 |
Inhibitory action of exogenous melatonin, 5-methoxytryptamine, and 6-hydroxymelatonin on sexual maturation of male rats: activity of 5-methoxytryptamine might be due to its conversion to melatonin.
Topics: 5-Methoxytryptamine; Acetylation; Animals; Biotransformation; Body Weight; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Melatonin; Organ Size; Pituitary Gland; Rats; Rats, Inbred Strains; Sexual Maturation; Spermatogenesis; Testosterone; Tryptamines | 1985 |
[Effect of indolamines and their analogs on the electric activity of on identified giant neuron of Achatina fulica Ferussac].
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Action Potentials; Animals; Cyproheptadine; Melatonin; Methysergide; Neurons; Serotonin; Structure-Activity Relationship; Tryptamines; Tryptophan | 1974 |
The pineal gland of the mole (Talpa europaea L.). VII. Activity of hydroxyindole-O-methyltransferase (HIOMT) in the formation of 5-methoxytryptophan, 5-methoxytryptamine, 5-methoxyindole-3-acetic acid, 5-methoxytryptophol and melantonin in the eyes and th
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Aging; Animals; Eulipotyphla; Eye; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Methyltransferases; Moles; Organ Specificity; Pineal Gland; Sex Factors; Sexual Maturation; Tryptamines; Tryptophan | 1981 |
5-Methoxyindoles in pineal gland of cow, pig, sheep and rat.
Topics: 5-Methoxytryptamine; Animals; Cattle; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Swine | 1981 |
Changes in the circadian rhythmicity of hydroxyindole-O-methyl transferase (HIOMT) activity in the synthesis of 5-methoxyindoles in the pineal gland of 28 day old male Wistar rats exposed to white, red and green light.
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Animals; Circadian Rhythm; Color Perception; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Methyltransferases; Pineal Gland; Rats; Rats, Inbred Strains | 1982 |
The influence of different 5-methoxyindoles on the process of protein/peptide secretion characterized by the formation of granular vesicles in the mouse pineal gland. An in vitro study.
Topics: 5-Methoxytryptamine; Animals; Cells, Cultured; Cytoplasmic Granules; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mice; Pineal Gland; Proteins; Tryptophan | 1983 |
Methoxyindole synthesis in the retina of the frog (Rana esculenta) during a diurnal period.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Hydroxyindoleacetic Acid; Indoles; Melatonin; Pigment Epithelium of Eye; Rana esculenta; Retina; Tryptophan | 1983 |
Morning injections of large doses of melatonin, but not of 5-methoxytryptamine, prevent in the hamster the antigonadotropic effect of 5-methoxytryptamine administered late in the afternoon.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Light; Male; Melatonin; Mesocricetus; Organ Size; Receptors, Cell Surface; Receptors, Melatonin; Testis; Time Factors; Tryptamines | 1982 |
Pineal methoxyindoles depress calcium uptake by rat brain synaptosomes.
Topics: 5-Methoxytryptamine; Animals; Brain; Calcium; Female; In Vitro Techniques; Indoles; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1984 |
Circadian information and messages in the modified photoreceptor cells of the avian pineal organ: retrospect and prospect.
Topics: 5-Methoxytryptamine; Animals; Birds; Circadian Rhythm; Indoles; Melatonin; Peptide Biosynthesis; Peptides; Photoreceptor Cells; Pineal Gland | 1984 |
Effects of injections and/or chronic implants of melatonin and 5-methoxytryptamine on plasma thyroid hormones in male and female Syrian hamsters.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Drug Implants; Female; Male; Melatonin; Mesocricetus; Thyroid Hormones; Thyroxine; Triiodothyronine; Tryptamines | 1984 |
Photoperiod perception in the blind mole rat (Spalax ehrenbergi, Nehring): involvement of the Harderian gland, atrophied eyes, and melatonin.
Topics: 5-Methoxytryptamine; Animals; Atrophy; Body Temperature Regulation; Female; Harderian Gland; Lacrimal Apparatus; Light; Melatonin; Moles; Ocular Physiological Phenomena; Perception; Periodicity; Photoreceptor Cells; Rats | 1984 |
Relative efficacy of melatonin and 5-methoxytryptamine in terms of their antigonadotrophic and counterantigonadotrophic actions in male Syrian hamsters.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Drug Implants; Gonadotropins; Male; Melatonin; Mesocricetus; Organ Size; Testis; Tryptamines | 1984 |
Seasonal variations in HIOMT activity during the night in the pineal gland of 21 day old male Wistar rats.
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Animals; Circadian Rhythm; Indoles; Isoenzymes; Male; Melatonin; Methyltransferases; Pineal Gland; Rats; Seasons; Tryptophan | 1980 |
In vivo formation of 5-methoxytryptamine from melatonin in rat.
Topics: 5-Methoxytryptamine; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Liver; Melatonin; Pargyline; Pineal Gland; Rats; Tryptamines | 1981 |
Concentration of 5-methoxyindoles in the human pineal gland.
Topics: 5-Methoxytryptamine; Aged; Female; Gas Chromatography-Mass Spectrometry; Humans; Indoleacetic Acids; Indoles; Male; Melatonin; Middle Aged; Pineal Gland; Tryptamines | 1982 |
A single radioimmunological assay for serotonin, N-acetylserotonin, 5-methoxytryptamine, and melatonin.
Topics: 5-Methoxytryptamine; Animals; Antibody Specificity; Chemical Phenomena; Chemistry; Circadian Rhythm; Male; Melatonin; Pineal Gland; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin; Tryptamines | 1982 |
An in vitro stimulatory effect of indoleamines on aldosterone biosynthesis in the rat.
Topics: 5-Methoxytryptamine; Adrenal Glands; Aldosterone; Animals; Dose-Response Relationship, Drug; Hyponatremia; Indoles; Lisuride; Melatonin; Rats; Serotonin | 1982 |
Ability of tryptophan derivatives to mimic melatonin's action upon the Syrian hamster reproductive system.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Organ Size; Pineal Gland; Testis; Tryptophan | 1982 |
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Melatonin deacetylase activity in the pineal gland and brain of the lizards Anolis carolinensis and Sceloporus jarrovi.
Topics: 5-Methoxytryptamine; Amidohydrolases; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Iguanas; Lizards; Melatonin; Organ Culture Techniques; Organ Specificity; Pargyline; Physostigmine; Pineal Gland; Species Specificity | 1994 |
Development of pre-implantation mouse embryos under the influence of pineal indoles.
Topics: 5-Methoxytryptamine; Abnormalities, Drug-Induced; Animals; Blastocyst; Embryonic and Fetal Development; Female; Fetal Death; Fetal Diseases; Fetal Resorption; Fetus; Hydroxyindoleacetic Acid; Indoles; Melatonin; Mice; Organ Culture Techniques; Organ Size; Pineal Gland; Pregnancy | 1994 |
Benzodiazepines influence melatonin secretion of the pineal organ of the trout in vitro.
Topics: 5-Methoxytryptamine; Animals; Benzodiazepines; Calcium; Clonazepam; Culture Media; Dark Adaptation; Diazepam; Flumazenil; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Isoquinolines; Light; Magnesium; Melatonin; Oncorhynchus mykiss; Pineal Gland | 1994 |
Three dimensional culture of pineal cell aggregates: a model of cell-cell co-operation.
Topics: 5-Methoxytryptamine; Animals; Cell Aggregation; Cell Communication; Cells, Cultured; Culture Media, Conditioned; Inclusion Bodies; Indoleacetic Acids; Indoles; Lysosomes; Male; Melatonin; Microscopy, Electron; Microscopy, Electron, Scanning; Models, Biological; Pineal Gland; Rats; Rats, Wistar | 1995 |
Changes induced by pineal indoles in post-implantation mouse embryos.
Topics: 5-Methoxytryptamine; Animals; Embryo Implantation; Embryonic and Fetal Development; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mice; Mice, Inbred ICR; Microscopy, Electron; Pineal Gland; Pregnancy | 1995 |
Secretion of methoxyindoles from trout pineal organs in vitro: indication for a paracrine melatonin feedback.
Topics: 5-Methoxytryptamine; Animals; Feedback; Hydroxyindoleacetic Acid; Indoles; Melatonin; Oncorhynchus mykiss; Organ Culture Techniques; Pineal Gland | 1995 |
Effects of long-term administration of melatonin and a putative antagonist on the ageing rat.
Topics: 5-Methoxytryptamine; Aging; Animals; Body Weight; Hypothalamus; Iodine Radioisotopes; Male; Medulla Oblongata; Melatonin; Pons; Random Allocation; Rats; Receptors, Cell Surface; Receptors, Melatonin; Survival Rate; Testosterone; Time Factors | 1995 |
On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals.
Topics: 5-Methoxytryptamine; Animals; Biological Evolution; Dinoflagellida; Free Radical Scavengers; Hydrogen-Ion Concentration; Kynuramine; Light; Melatonin; Monoamine Oxidase; Oxidants, Photochemical; Photoperiod; Signal Transduction | 1995 |
Potential radioprotective agents--V. Melatonin analogs. Oral activity of p-aminopropiophenone and its ethylene ketal.
Topics: 5-Methoxytryptamine; Amides; Animals; Magnetic Resonance Spectroscopy; Melatonin; Mice; Mice, Inbred Strains; Propiophenones; Radiation-Protective Agents | 1994 |
5-Methoxytryptamine inhibits cyclic AMP accumulation in cultured retinal neurons through activation of a pertussis toxin-sensitive site distinct from the 2-[125I]iodomelatonin binding site.
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Cells, Cultured; Chick Embryo; Cyclic AMP; Melatonin; Neurons; Pertussis Toxin; Retina; Virulence Factors, Bordetella | 1995 |
Effect of neonatal melatonin and 5-methoxytriptamine administration on the female Indian palm squirrel (Funambulus pennanti).
Topics: 5-Methoxytryptamine; Animals; Animals, Newborn; Body Weight; Estradiol; Female; Hair; Injections, Subcutaneous; Melatonin; Organ Size; Sciuridae; Skin Pigmentation | 1994 |
Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes.
Topics: 5-Methoxytryptamine; Acetates; Carbon Radioisotopes; Cholesterol; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Leukocytes, Mononuclear; Lipoproteins, LDL; Melatonin; Mevalonic Acid; Receptors, LDL; Serotonin; Tryptamines | 1994 |
Stimulation of murine splenocytes by melatonin and methoxytryptamine.
Topics: 5-Methoxytryptamine; Animals; Cell Line; Concanavalin A; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Mastocytosis; Melatonin; Mice; Mice, Inbred C57BL; Mitogens; Nitrites; Spleen; Stimulation, Chemical | 1993 |
Potential radioprotective agents. 1. Homologs of melatonin.
Topics: 5-Methoxytryptamine; Acylation; Amides; Animals; Injections, Intraperitoneal; Male; Melatonin; Mice; Photons; Radiation-Protective Agents; Structure-Activity Relationship | 1994 |
Action of pineal indoleamines on the reproductive systems of the male C57 mouse and golden hamster.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Genitalia, Male; Indoles; Male; Melatonin; Mesocricetus; Mice; Mice, Inbred C57BL; Pineal Gland; Seminal Vesicles; Seminiferous Tubules; Testis | 1993 |
N-bromoacetyl 5-methoxytryptamine: an irreversible melatonin ligand?
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Chickens; Iodine Radioisotopes; Kinetics; Melatonin; Receptors, Melatonin; Receptors, Neurotransmitter; Structure-Activity Relationship; Tryptamines | 1993 |
Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells.
Topics: 5-Methoxytryptamine; Animals; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Melanins; Melanoma, Experimental; Melatonin; Mice; Serotonin; Thymidine; Tumor Cells, Cultured | 1993 |
Selective effect of methoxyindoles on the lymphocyte proliferation and melatonin binding to activated human lymphoid cells.
Topics: 5-Methoxytryptamine; Adult; Cell Division; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Immunologic; Humans; Indoles; Lymphocyte Activation; Lymphocytes; Melatonin; Middle Aged; Mitogens; Protein Binding; Staphylococcal Protein A; Tetanus Toxoid | 1995 |
Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.
Topics: 5-Methoxytryptamine; Animals; Chromatography, High Pressure Liquid; Colforsin; Cricetinae; Gas Chromatography-Mass Spectrometry; Male; Melatonin; Mesocricetus; Organ Culture Techniques; Serotonin; Skin; Tritium | 1996 |
Chronobiology of indoleamines in the dinoflagellate Gonyaulax polyedra: metabolism and effects related to circadian rhythmicity and photoperiodism.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Dinoflagellida; Luminescent Measurements; Melatonin; Photosynthesis; Temperature; Tryptophan Hydroxylase | 1996 |
Effects of pineal indoles on ovarian response to gonadotropin-induced ovulation in mice.
Topics: 5-Methoxytryptamine; Animals; Estradiol; Female; Gonadotropins; Hydroxyindoleacetic Acid; Indoles; Melatonin; Mice; Mice, Inbred ICR; Oocytes; Ovarian Follicle; Ovary; Ovulation; Pineal Gland; Progesterone; Time Factors | 1995 |
Secretion of the methoxyindoles melatonin, 5-methoxytryptophol, 5-methoxyindoleacetic acid, and 5-methoxytryptamine from trout pineal organs in superfusion culture: effects of light intensity.
Topics: 5-Methoxytryptamine; Animals; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Dark Adaptation; Hydroxyindoleacetic Acid; Indoles; Light; Melatonin; Monoamine Oxidase Inhibitors; Oncorhynchus mykiss; Organ Culture Techniques; Pargyline; Perfusion; Physostigmine; Pineal Gland | 1996 |
Evolutionary aspects of indoleamines as radical scavengers. Presence and photocatalytic turnover of indoleamines in a unicell, Gonyaulax polyedra.
Topics: 5-Methoxytryptamine; Animals; Biological Evolution; Catalysis; Circadian Rhythm; Dinoflagellida; Free Radical Scavengers; Melatonin; Photochemistry; Temperature; Tryptophan; Tryptophan Hydroxylase | 1996 |
CGP 52608-induced cyst formation in dinoflagellates: possible involvement of a nuclear receptor for melatonin.
Topics: 5-Methoxytryptamine; Animals; Dinoflagellida; Dose-Response Relationship, Drug; Endocytosis; GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Melatonin; Peptides; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Thiazoles; Thiosemicarbazones; Transcription Factors; Transcription, Genetic; Wasp Venoms | 1996 |
Harderian gland function of Indian tropical palm squirrel, Funambulus pennanti.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Cricetinae; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropins; Harderian Gland; Male; Melatonin; Orchiectomy; Ovariectomy; Photoperiod; Pineal Gland; Sciuridae; Seasons; Testosterone | 1996 |
Calcium ion dependency and the role of inositol phosphates in melatonin-induced encystment of dinoflagellates.
Topics: 5-Methoxytryptamine; Animals; Calcium; Cysts; Dinoflagellida; Dose-Response Relationship, Drug; Inositol Phosphates; Melatonin; Signal Transduction; Time Factors; Type C Phospholipases | 1997 |
Retinal 5-methoxytryptamine and 5-methoxyindole-3-acetic acid in the rat and quail: diurnal rhythms and interspecies differences.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Male; Melatonin; Quail; Rats; Rats, Sprague-Dawley; Retina; Species Specificity | 1997 |
Pineal and 5-methoxyindoles in the regulation of seasonal testicular cycle in Indian palm squirrel, Funambulus pennanti.
Topics: 5-Methoxytryptamine; Animals; Male; Melatonin; Periodicity; Pineal Gland; Sciuridae; Seasons; Testis | 1997 |
Melatonin receptor pharmacology: toward subtype specificity.
Topics: 3T3 Cells; 5-Methoxytryptamine; Acetylation; Animals; Binding Sites; Binding, Competitive; Clone Cells; Cloning, Molecular; GTP-Binding Proteins; Humans; Ligands; Melanocytes; Melanophores; Melatonin; Methylation; Mice; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serotonin; Species Specificity; Structure-Activity Relationship; Transfection; Tryptamines; Xenopus laevis | 1997 |
Effect of pineal indoles on the chick embryo.
Topics: 5-Methoxytryptamine; Animals; Chick Embryo; Indoles; Melatonin; Pineal Gland | 1999 |
Hypotensive activity of the pineal indoleamine hormones melatonin, 5-methoxytryptophol and 5-methoxytryptamine.
Topics: 5-Methoxytryptamine; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Injections, Intravenous; Lidocaine; Male; Melatonin; Methylene Blue; Rats; Rats, Sprague-Dawley | 2000 |
Melatonin and 5-methoxytryptamine in the bioluminescent dinoflagellate Gonyaulax polyedra. Restoration of the circadian glow peak after suppression of indoleamine biosynthesis or oxidative stress.
Topics: 5-Methoxytryptamine; Animals; Buthionine Sulfoximine; Circadian Rhythm; Dinoflagellida; Hydrogen Peroxide; Indoles; Luminescent Measurements; Melatonin; Oxidative Stress; Paraquat; Photoperiod | 1999 |
Hydroxypropyl-beta-cyclodextrin enhanced fluorimetric method for the determination of melatonin and 5-methoxytryptamine.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; 5-Methoxytryptamine; alpha-Cyclodextrins; Animals; beta-Cyclodextrins; Cyclodextrins; Fluorometry; gamma-Cyclodextrins; Melatonin; Pineal Gland; Rats | 2000 |
Effect of pineal indoles on activities of the antioxidant defense enzymes superoxide dismutase, catalase, and glutathione reductase, and levels of reduced and oxidized glutathione in rat tissues.
Topics: 5-Methoxytryptamine; Animals; Antioxidants; Brain; Brain Chemistry; Catalase; Free Radical Scavengers; Glutathione; Glutathione Reductase; Indoles; Kidney; Liver; Male; Melatonin; Oxidation-Reduction; Pineal Gland; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2000 |
Pineal indoles stimulate the gene expression of immunomodulating cytokines.
Topics: 5-Methoxytryptamine; Adjuvants, Immunologic; Animals; Anti-Anxiety Agents; Cytokines; DNA Primers; Exudates and Transudates; Gene Expression; Indoles; Injections, Intraperitoneal; Interferon-gamma; Interleukin-1; Macrophage Colony-Stimulating Factor; Male; Melatonin; Mice; Mice, Inbred C57BL; Peritoneum; Pineal Gland; Spleen; Stem Cell Factor; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
[Morphofunctional changes in the pineal gland during adaptation to hypothermia].
Topics: 5-Methoxytryptamine; Adaptation, Physiological; Animals; Cold Temperature; Fluorometry; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin | 2001 |
Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible.
Topics: 5-Methoxytryptamine; Acetylation; Animals; Binding, Competitive; Cells, Cultured; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Iodine Radioisotopes; Melanophores; Melanosomes; Melatonin; Monoamine Oxidase Inhibitors; Physostigmine; Pigments, Biological; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Xenopus laevis | 2002 |
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors.
Topics: 5-Methoxytryptamine; Amyloid beta-Peptides; Animals; Antioxidants; Cells, Cultured; Cyclic N-Oxides; Free Radical Scavengers; Hippocampus; Humans; Melatonin; Neuroblastoma; Neurons; Neuroprotective Agents; Nitrogen Oxides; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serotonin | 2002 |
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs.
Topics: 5-Methoxytryptamine; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Molecular Biology; Oxidation-Reduction; Serotonin; Solubility; Structure-Activity Relationship; Superoxides; Tryptamines | 2002 |
Photoperiod affects amplitude but not duration of in vitro melatonin production in the ruin lizard (Podarcis sicula).
Topics: 5-Methoxytryptamine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Darkness; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Lizards; Male; Melatonin; Photoperiod; Pineal Gland; Seasons | 2003 |
Fourier transform infrared spectra and molecular structure of 5-methoxytryptamine, N-acetyl-5-methoxytryptamine and N-phenylsulfonamide-5-methoxytryptamine.
Topics: 5-Methoxytryptamine; Melatonin; Models, Molecular; Protein Conformation; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Sulfonamides; X-Ray Diffraction | 2003 |
Functional activity of serotoninergic and melatoninergic systems expressed in the skin.
Topics: 5-Methoxytryptamine; Amino Acid Sequence; Apoptosis; Base Sequence; Cell Division; Cells, Cultured; Gene Expression; Humans; Melatonin; Phenotype; Pituitary Gland; Protein Isoforms; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Skin | 2003 |
The metabolism of melatonin (N-acetyl-5-methoxytryptamine) and 5-methoxytryptamine.
Topics: 5-Methoxytryptamine; Humans; Indoles; Melatonin | 1961 |
Involvement of melatonin metabolites in the long-term inhibitory effect of the hormone on rat spinal nociceptive transmission.
Topics: 5-Methoxytryptamine; Amidohydrolases; Animals; Cholinesterase Inhibitors; Electric Stimulation; Male; Melatonin; Nerve Fibers, Unmyelinated; Nociceptors; Physostigmine; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Synaptic Transmission | 2004 |
The actions of a charged melatonin receptor ligand, TMEPI, and an irreversible MT2 receptor agonist, BMNEP, on mouse hippocampal evoked potentials in vitro.
Topics: 5-Methoxytryptamine; Amides; Animals; Electrophysiology; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Hippocampus; Ligands; Male; Melatonin; Metallothionein; Mice; Quaternary Ammonium Compounds; Receptors, Melatonin; Time Factors | 2004 |
Recovery of experimental Parkinson's disease with the melatonin analogues ML-23 and S-20928 in a chronic, bilateral 6-OHDA model: a new mechanism involving antagonism of the melatonin receptor.
Topics: 5-Methoxytryptamine; Animals; Male; Melatonin; Naphthalenes; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Recovery of Function | 2004 |
Indoleamines and 5-methoxyindoles in trout pineal organ in vivo: daily changes and influence of photoperiod.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Hydroxyindoleacetic Acid; Indoles; Melatonin; Oncorhynchus mykiss; Photoperiod; Pineal Gland | 2005 |
Solvent effects in the preparation of molecularly imprinted polymers for melatonin using N-propionyl-5-methoxytryptamine as the pseudo template.
Topics: 5-Methoxytryptamine; Binding Sites; Chromatography, High Pressure Liquid; Hydrogen Bonding; Melatonin; Methacrylates; Molecular Mimicry; Polymers; Solvents; Stereoisomerism | 2006 |
The effect of melatonin and structural analogues on the lipid peroxidation of triglycerides enriched in omega-3 polyunsaturated fatty acids.
Topics: 5-Methoxytryptamine; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Cell-Free System; Docosahexaenoic Acids; Fatty Acids, Omega-3; Free Radical Scavengers; Kynuramine; Lipid Peroxidation; Lipids; Luminescent Measurements; Melatonin; Oxidation-Reduction; Picrates; Reactive Oxygen Species; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan | 2007 |
MT1 melatonin receptors mediate somatic, behavioral, and reproductive neuroendocrine responses to photoperiod and melatonin in Siberian hamsters (Phodopus sungorus).
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Cricetinae; Indenes; Male; Melatonin; Motor Activity; Phodopus; Photoperiod; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Seasons; Signal Transduction | 2010 |
Preliminary analgesic properties of deltorphin-5-methoxytryptamine chimeric opioid peptides.
Topics: 5-Methoxytryptamine; Analgesics; Animals; Male; Melatonin; Mice; Oligopeptides; Opioid Peptides; Pain | 2011 |
The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system.
Topics: 5-Methoxytryptamine; Antioxidants; Benzene Derivatives; Biphenyl Compounds; Butylated Hydroxytoluene; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Lipid Peroxidation; Lysosomes; Melatonin; Picrates; Serotonin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tryptophan | 2012 |
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.
Topics: 5-Methoxytryptamine; Animals; Cell Differentiation; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Female; Fibroblasts; Humans; Keratin-10; Keratin-14; Keratinocytes; Kinetics; Kynuramine; Melanocytes; Melanoma; Melatonin; Metabolic Networks and Pathways; Serotonin; Skin; Spectrometry, Mass, Electrospray Ionization; Swine | 2013 |
Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.
Topics: 5-Methoxytryptamine; Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Proliferation; Cells, Cultured; Epidermis; Female; Humans; In Vitro Techniques; Kynuramine; Male; Melanocytes; Melanoma; Melatonin; Middle Aged; Protein-Tyrosine Kinases; Sex Factors; Skin Neoplasms; White People | 2015 |
Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.
Topics: 5-Methoxytryptamine; Animals; Brain; Cytochrome P-450 Enzyme System; Male; Melatonin; Microdialysis; Neurotransmitter Agents; Rats; Rats, Wistar; Serotonin | 2016 |
The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury.
Topics: 5-Methoxytryptamine; Acute Radiation Syndrome; Animals; DNA Damage; Hematopoiesis; Histones; Male; Melatonin; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; NADPH Oxidases; Radiation-Protective Agents; Radiation, Ionizing; Reactive Oxygen Species; Thioctic Acid | 2016 |
Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin.
Topics: 5-Methoxytryptamine; Animals; Antioxidants; Autophagy; Cell Line; Cell Proliferation; Cell Survival; Glutamic Acid; HEK293 Cells; Hippocampus; Humans; Melatonin; Mice; Neuroprotective Agents | 2016 |
Chloroplast overexpression of rice caffeic acid O-methyltransferase increases melatonin production in chloroplasts via the 5-methoxytryptamine pathway in transgenic rice plants.
Topics: 5-Methoxytryptamine; Cadmium; Chloroplasts; Cloning, Molecular; Melatonin; Methyltransferases; Oryza; Plants, Genetically Modified; Seedlings | 2017 |
Metabolic analysis of the melatonin biosynthesis pathway using chemical labeling coupled with liquid chromatography-mass spectrometry.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Chromatography, Liquid; Mass Spectrometry; Melatonin; Serotonin; Tryptamines; Tryptophan | 2019 |
Changes in the Metabolic Profile of Melatonin Synthesis-Related Indoles during Post-Embryonic Development of the Turkey Pineal Organ.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Circadian Rhythm; Embryonic Development; Hydroxyindoleacetic Acid; Indoles; Melatonin; Metabolome; Pineal Gland; Serotonin; Tryptophan | 2022 |
Alternative Ligands at Melatonin Receptors.
Topics: 5-Methoxytryptamine; Animals; Iodine Radioisotopes; Ligands; Mammals; Melatonin; Receptors, Melatonin | 2022 |
Measuring Binding at the Putative Melatonin Receptor MT3.
Topics: 5-Methoxytryptamine; Animals; Antioxidants; Binding Sites; Ligands; Mammals; Melatonin; Quinone Reductases; Receptors, Melatonin | 2022 |
Cloning, Expression, Purification, Crystallization, and X-Ray Structural Determination of the Human NQO2 in Complex with Melatonin.
Topics: 5-Methoxytryptamine; Animals; Antioxidants; Cloning, Molecular; Crystallization; Humans; Ligands; Mammals; Melatonin; Quinone Reductases; Receptors, Melatonin; X-Rays | 2022 |
Melanogenesis Is Directly Affected by Metabolites of Melatonin in Human Melanoma Cells.
Topics: 5-Methoxytryptamine; Humans; Melanins; Melanoma; Melatonin; Monophenol Monooxygenase; Receptor, Melatonin, MT2 | 2023 |