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5-methoxyluzindole and melatonin

5-methoxyluzindole has been researched along with melatonin in 5 studies

*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]

*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]

Compound Research Comparison

Studies
(5-methoxyluzindole)
Trials
(5-methoxyluzindole)
Recent Studies (post-2010)
(5-methoxyluzindole)
Studies
(melatonin)
Trials
(melatonin)
Recent Studies (post-2010) (melatonin)
50223,2681,4519,627

Protein Interaction Comparison

ProteinTaxonomy5-methoxyluzindole (IC50)melatonin (IC50)
MyeloperoxidaseHomo sapiens (human)3
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)3.3323
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0004
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0005
Melatonin receptor type 1AHomo sapiens (human)0.0025
Melatonin receptor type 1BHomo sapiens (human)0.0035

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM1
Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G1
Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP1
Laborda, P; Shi, XC; Wang, SY1
Dubocovich, ML; Duncan, MJ; Fang, JM1

Reviews

1 review(s) available for 5-methoxyluzindole and melatonin

ArticleYear
Indole-based melatonin analogues: Synthetic approaches and biological activity.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship

2020

Other Studies

4 other study(ies) available for 5-methoxyluzindole and melatonin

ArticleYear
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:3

    Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina

1997
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi

1998
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
    Journal of medicinal chemistry, 2014, Apr-24, Volume: 57, Issue:8

    Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship

2014
Effects of melatonin agonists and antagonists on reproduction and body weight in the Siberian hamster.
    Journal of pineal research, 1990, Volume: 9, Issue:4

    Topics: Animals; Binding, Competitive; Body Weight; Cricetinae; Light; Male; Median Eminence; Melatonin; Methysergide; Organ Size; Periodicity; Pituitary Gland, Anterior; Receptors, Melatonin; Receptors, Neurotransmitter; Testis; Tryptamines

1990