Page last updated: 2024-09-04

5-methoxy-n,n-diisopropyltryptamine and 5-methoxytryptamine

5-methoxy-n,n-diisopropyltryptamine has been researched along with 5-methoxytryptamine in 32 studies

Compound Research Comparison

Studies
(5-methoxy-n,n-diisopropyltryptamine)
Trials
(5-methoxy-n,n-diisopropyltryptamine)
Recent Studies (post-2010)
(5-methoxy-n,n-diisopropyltryptamine)
Studies
(5-methoxytryptamine)
Trials
(5-methoxytryptamine)
Recent Studies (post-2010) (5-methoxytryptamine)
34010685767

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.13)18.7374
1990's0 (0.00)18.2507
2000's21 (65.63)29.6817
2010's7 (21.88)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Carter, MF; Shulgin, AT1
Muller, AA1
Kiyota, K1
Alder, JF; Brandt, SD; Fleet, IA; Freeman, S; McGagh, P1
Sklerov, JH; Vorce, SP1
McGeorge, F; Meatherall, R; Smolinske, S; Wilson, JM1
Ikeda, N; Inoue, H; Ishida, T; Kiyoshima, A; Kudo, K; Tsuji, A1
Honda, K; Kamata, HT; Kamata, T; Katagi, M; Miki, A; Nishikawa, M; Shima, N; Tanaka, E; Tsuchihashi, H; Zaitsu, K1
Honda, K; Kamata, T; Katagi, M; Tanaka, E; Tsuchihashi, H1
Coop, A; Eckler, JR; Fantegrossi, WE; Harrington, AW; Kiessel, CL; Rabin, RA; Rice, KC; Winter, JC; Woods, JH1
Asanuma, M; Funada, M; Hanioka, N; Ishikawa, T; Kiryu, K; Kumamoto, T; Naito, S; Narimatsu, S; Saito, K; Takaya, K; Yamamoto, S; Yonemoto, R; Yoshida, Y1
Alatrash, G; Majhail, NS; Pile, JC1
Compton, DM; Larkins, KD; Selinger, MC; Testa, EK1
Hidaka, Y; Ichikawa, S; Kihara, M; Kimura, H; Koyano, J; Ono-Kihara, M; Urao, M; Yasuo, T1
Campbell, NG; Herring, NR; Lipton, JW; McCrea, AE; Schaefer, TL; Skelton, MR; Vorhees, CV; Williams, MT1
Abe, Y; Arai, M; Hobo, M; Inoue, K; Itokawa, M; Iwata, K; Jitoku, D; Sasaki, T; Shintani, M; Sugihara, G; Takahashi, M; Uno, M; Yasuda, I1
Asanuma, M; Fujino, A; Funada, M; Kitayama, S; Ohyama, K; Sogawa, C; Sogawa, N; Tagawa, J1
Asanuma, M; Hanioka, N; Ishikawa, T; Kamata, T; Katagi, M; Katsu, T; Kumamoto, T; Masuda, K; Naito, S; Narimatsu, S; Tsuchihashi, H; Yamano, S; Yonemoto, R1
Rastogi, R; Schenkel, S; Smolinske, SC1
Asanuma, M; Funae, Y; Hagino, S; Hanioka, N; Ishikawa, T; Katsu, T; Kazamori, D; Kiryu, K; Kobatake, M; Kumamoto, T; Masuda, K; Naito, S; Narimatsu, S; Yamano, S; Yonemoto, R; Yoshino, M1
Kaneko, S; Nakagawa, T1
Kuwahara, T; Makie, T; Mori, M; Nakakura, T; Oda, S; Okamoto, G; Sasakawa, A; Takada, K; Uehira, T; Umemoto, A; Yajima, K; Yamamoto, Y; Yoshino, M1
Compton, DM; Dietrich, KL; Selinger, MC; Testa, EK1
In, MK; Jin, C; Jin, MJ; Kim, JY; Kwon, OS; Yoo, HH1
Fuse-Nagase, Y; Nishikawa, T1
Gołembiowska, K; Kamińska, K; Kreiner, G; Noworyta-Sokołowska, K; Rogóż, Z1
Barneo-Muñoz, M; Fabregat-Safont, D; Hernández, F; Ibáñez, M; Martinez-Garcia, F; Sancho, JV1
Górska, AM; Gołembiowska, K; Noworyta-Sokołowska, K1
Le, A; Palamar, JJ1
Xiang, P; Yan, H; Yan, X; Yu, Z; Zhao, Y1
Wu, H; Xiang, P; Yan, H; Yan, X; Yu, Z; Yuan, S; Zhang, S; Zhao, Y1
Hagino, Y; Hall, FS; Ikeda, K; Sora, I; Uhl, GR1

Reviews

2 review(s) available for 5-methoxy-n,n-diisopropyltryptamine and 5-methoxytryptamine

ArticleYear
[Latest cases of acute poisoning in clinical practice--5MeO-DIPT and GHB precursor].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2004, Volume: 17, Issue:3

    Topics: 5-Methoxytryptamine; Acute Disease; Adult; Designer Drugs; Female; Humans; Male; Sodium Oxybate

2004
Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy).
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamine; Humans; Limbic System; Membrane Potentials; Mesencephalon; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Oocytes; Organ Culture Techniques; Raphe Nuclei; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Xenopus

2008

Other Studies

30 other study(ies) available for 5-methoxy-n,n-diisopropyltryptamine and 5-methoxytryptamine

ArticleYear
N, N-Diisopropyltryptamine (DIPT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT). Two orally active tryptamine analogs with CNS activity.
    Communications in psychopharmacology, 1980, Volume: 4, Issue:5

    Topics: 5-Methoxytryptamine; Hallucinogens; Hearing; Humans; Tryptamines

1980
New drugs of abuse update: Foxy Methoxy.
    Journal of emergency nursing, 2004, Volume: 30, Issue:5

    Topics: 5-Methoxytryptamine; Designer Drugs; Hallucinogens; Humans

2004
Analytical chemistry of synthetic routes to psychoactive tryptamines. Part I. Characterisation of the Speeter and Anthony synthetic route to 5-methoxy-N,N-diisopropyltryptamine using ESI-MS-MS and ESI-TOF-MS.
    The Analyst, 2004, Volume: 129, Issue:11

    Topics: 5-Methoxytryptamine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Psychotropic Drugs; Spectrometry, Mass, Electrospray Ionization

2004
A general screening and confirmation approach to the analysis of designer tryptamines and phenethylamines in blood and urine using GC-EI-MS and HPLC-electrospray-MS.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: 5-Methoxytryptamine; Chromatography, High Pressure Liquid; Dealkylation; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Phenethylamines; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tryptamines

2004
A foxy intoxication.
    Forensic science international, 2005, Feb-10, Volume: 148, Issue:1

    Topics: 5-Methoxytryptamine; Adult; Cyclic N-Oxides; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyindoleacetic Acid; Male; Paranoid Disorders; Paresthesia

2005
Sensitive determination of alpha-methyltryptamine (AMT) and 5-methoxy-N,N-diisopropyltryptamine (5MeO-DIPT) in whole blood and urine using gas chromatography-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Aug-25, Volume: 823, Issue:1

    Topics: 5-Methoxytryptamine; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Tryptamines

2005
Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N,N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:2

    Topics: 5-Methoxytryptamine; Adult; Chromatography, Liquid; Dementia; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male

2006
A fatal poisoning with 5-methoxy-N,N-diisopropyltryptamine, Foxy.
    Forensic science international, 2006, Nov-10, Volume: 163, Issue:1-2

    Topics: 5-Methoxytryptamine; Adult; Autopsy; Diagnosis, Differential; Hallucinogens; Homosexuality, Male; Humans; Male; Mass Spectrometry; Poisoning

2006
Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Brain; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; Lysergic Acid Diethylamide; Male; Mice; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists

2006
Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Biochemical pharmacology, 2006, Apr-28, Volume: 71, Issue:9

    Topics: 5-Methoxytryptamine; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Oxidation-Reduction; Recombinant Proteins

2006
Rhabdomyolysis after ingestion of "foxy," a hallucinogenic tryptamine derivative.
    Mayo Clinic proceedings, 2006, Volume: 81, Issue:4

    Topics: 5-Methoxytryptamine; Adult; Diagnosis, Differential; Diuretics; Fluid Therapy; Hallucinogens; Humans; Male; Rhabdomyolysis

2006
An examination of the effects of 5-Methoxy-n, n-di(ISO)propyltryptamine hydrochloride (Foxy) on cognitive development in rats.
    Psychological reports, 2006, Volume: 98, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Cognition; Perceptual Disorders; Random Allocation; Rats; Rats, Long-Evans; Space Perception

2006
Substance use and sexual behaviours of Japanese men who have sex with men: a nationwide internet survey conducted in Japan.
    BMC public health, 2006, Sep-26, Volume: 6

    Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Amyl Nitrite; Health Knowledge, Attitudes, Practice; Health Surveys; HIV Infections; Homosexuality, Male; Humans; Internet; Japan; Male; Marijuana Abuse; Middle Aged; Periodicals as Topic; Risk-Taking; Substance-Related Disorders; Surveys and Questionnaires; Unsafe Sex

2006
Alterations in body temperature, corticosterone, and behavior following the administration of 5-methoxy-diisopropyltryptamine ('foxy') to adult rats: a new drug of abuse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:6

    Topics: 5-Methoxytryptamine; Animals; Behavior, Animal; Biogenic Monoamines; Body Temperature; Body Weight; Brain Chemistry; Central Nervous System Stimulants; Corticosterone; Data Interpretation, Statistical; Designer Drugs; Dose-Response Relationship, Drug; Male; Maze Learning; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Swimming

2007
Acute confusional state after designer tryptamine abuse.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:2

    Topics: 5-Methoxytryptamine; Adult; Confusion; Designer Drugs; Female; Gas Chromatography-Mass Spectrometry; Glasgow Coma Scale; Humans; Serotonin; Substance-Related Disorders; Tryptamines

2007
5-Methoxy-N,N-diisopropyltryptamine (Foxy), a selective and high affinity inhibitor of serotonin transporter.
    Toxicology letters, 2007, Apr-05, Volume: 170, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Biogenic Monoamines; Cell Survival; Chlorocebus aethiops; Cocaine; Male; Methamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Synaptosomes

2007
Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
    Biochemical pharmacology, 2008, Feb-01, Volume: 75, Issue:3

    Topics: 5-Methoxytryptamine; Animals; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Female; Humans; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Wistar; Recombinant Proteins

2008
Foxy methoxy: a new drug of abuse.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2005, Volume: 1, Issue:1

    Topics: 5-Methoxytryptamine; Adult; Anti-Anxiety Agents; Catalepsy; Emergency Medical Services; Hallucinations; Humans; Hypertension; Illicit Drugs; Lorazepam; Male; Mydriasis; Poisoning; Tachycardia; Treatment Outcome

2005
The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
    Chemico-biological interactions, 2008, Mar-10, Volume: 172, Issue:1

    Topics: 5-Methoxytryptamine; Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P450 Family 2; Enzyme Stability; Gene Expression Regulation; Microsomes; Molecular Structure; Mutation; Oxidation-Reduction; Rats; Saccharomyces cerevisiae

2008
Problems in three Japanese drug users with Human Immunodeficiency Virus infection.
    The journal of medical investigation : JMI, 2008, Volume: 55, Issue:1-2

    Topics: 5-Methoxytryptamine; Adult; Amyl Nitrite; Antiretroviral Therapy, Highly Active; Asian People; Drug Interactions; HIV Infections; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Rhabdomyolysis; Seizures; Substance-Related Disorders

2008
5-methoxy-N,N-di(iso)propyltryptamine hydrochloride (Foxy)-induced cognitive deficits in rat after exposure in adolescence.
    Physiology & behavior, 2011, May-03, Volume: 103, Issue:2

    Topics: 5-Methoxytryptamine; Age Factors; Animals; Cognition Disorders; Hallucinogens; Male; Maze Learning; Prosencephalon; Rats; Rats, Long-Evans; Rotarod Performance Test; Serotonin; Spatial Behavior

2011
A quantitative method for simultaneous determination of 5-methoxy-N,N-diisopropyltryptamine and its metabolites in urine using liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Journal of forensic sciences, 2011, Volume: 56, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Chromatography, Liquid; Designer Drugs; Forensic Toxicology; Hallucinogens; Rats; Serotonin; Spectrometry, Mass, Electrospray Ionization

2011
Prolonged delusional state triggered by repeated ingestion of aromatic liquid in a past 5-methoxy-N, N-diisopropyltryptamine abuser.
    Addiction science & clinical practice, 2013, Apr-11, Volume: 8, Issue:1

    Topics: 5-Methoxytryptamine; Adult; Delusions; Humans; Male; Mental Disorders; Substance-Related Disorders

2013
Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats.
    Neurotoxicity research, 2016, Volume: 30, Issue:4

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Corpus Striatum; DNA Damage; Dopamine; Frontal Lobe; Glutamic Acid; Hallucinogens; Illicit Drugs; Male; Microdialysis; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Oxidative Stress; Rats, Wistar; Serotonin

2016
Proposal of 5-methoxy-N-methyl-N-isopropyltryptamine consumption biomarkers through identification of in vivo metabolites from mice.
    Journal of chromatography. A, 2017, Jul-28, Volume: 1508

    Topics: 5-Methoxytryptamine; Animals; Biomarkers; Chromatography, High Pressure Liquid; Europe; Illicit Drugs; Male; Mass Spectrometry; Mice

2017
The effect of repeated-intermittent exposure to 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) during adolescence on learning and memory in adult rats.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: 5-Methoxytryptamine; Age Factors; Animals; Learning; Male; Memory; Rats

2018
Trends in DMT and other tryptamine use among young adults in the United States.
    The American journal on addictions, 2018, Volume: 27, Issue:7

    Topics: 5-Methoxytryptamine; Female; Hallucinogens; Humans; Male; N,N-Dimethyltryptamine; Prevalence; Substance-Related Disorders; Tryptamines; United States; Young Adult

2018
Determination of 5-MeO-DIPT in Human Urine Using Gas Chromatography Coupled with High-Resolution Orbitrap Mass Spectrometry.
    Journal of analytical toxicology, 2020, Apr-02, Volume: 44, Issue:5

    Topics: 5-Methoxytryptamine; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Serotonin; Substance Abuse Detection

2020
Development of an LC-MS/MS method for determining 5-MeO-DIPT in dried urine spots and application to forensic cases.
    Journal of forensic and legal medicine, 2020, Volume: 72

    Topics: 5-Methoxytryptamine; Chromatography, Liquid; Desiccation; Drug Stability; Forensic Toxicology; Hallucinogens; Humans; Limit of Detection; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2020
Dual actions of 5-MeO-DIPT at the serotonin transporter and serotonin 5-HT
    Neuropsychopharmacology reports, 2021, Volume: 41, Issue:1

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Female; Male; Mice; Mice, Knockout; Microdialysis; Piperazines; Prefrontal Cortex; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins

2021