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5-methoxy-6-methyl-2-aminoindan and fluoxetine

5-methoxy-6-methyl-2-aminoindan has been researched along with fluoxetine in 3 studies

Compound Research Comparison

Studies
(5-methoxy-6-methyl-2-aminoindan)
Trials
(5-methoxy-6-methyl-2-aminoindan)
Recent Studies (post-2010)
(5-methoxy-6-methyl-2-aminoindan)
Studies
(fluoxetine)
Trials
(fluoxetine)
Recent Studies (post-2010) (fluoxetine)
130010,1001,6633,263

Protein Interaction Comparison

ProteinTaxonomy5-methoxy-6-methyl-2-aminoindan (IC50)fluoxetine (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)5.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.119
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.303
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.358
Cytochrome P450 2D6Homo sapiens (human)0.7
Muscarinic acetylcholine receptor M1Homo sapiens (human)3.203
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)5.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.528
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)5.2
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.595
AcetylcholinesteraseHomo sapiens (human)0.13
Prostaglandin G/H synthase 1Homo sapiens (human)6
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.8332
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)6
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.452
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.1395
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)5.2
Sodium-dependent serotonin transporterHomo sapiens (human)0.0342
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.0538
Cytochrome P450 2C19Homo sapiens (human)0.0525
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)5.2
5-hydroxytryptamine receptor 6Homo sapiens (human)1.661
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)5.2
Sodium-dependent dopamine transporter Homo sapiens (human)5.984
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.3513
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)5.2
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0094
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)5.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.6751
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)5.2
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)5.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Callaway, CW; Geyer, MA; Nichols, DE; Wing, LL1
Brownfield, MS; Levy, AD; Li, Q; Murakami, I; Nichols, DE; Stall, S; Van de Kar, LD1
Marona-Lewicka, D; Nichols, DE1

Other Studies

3 other study(ies) available for 5-methoxy-6-methyl-2-aminoindan and fluoxetine

ArticleYear
Suppression of behavioral activity by norfenfluramine and related drugs in rats is not mediated by serotonin release.
    Psychopharmacology, 1993, Volume: 111, Issue:2

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fenclonine; Fluoxetine; Indans; Male; Methiothepin; Motor Activity; Norfenfluramine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Stereoisomerism

1993
Neuroendocrine pharmacology of three serotonin releasers: 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butane (MBDB), 5-methoxy-6-methyl-2-aminoindan (MMAi) and p-methylthioamphetamine (MTA).
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Fluoxetine; Indans; Male; Oxytocin; Prolactin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vasopressins

1996
Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents.
    Psychopharmacology, 1998, Volume: 138, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antidepressive Agents, Second-Generation; Citalopram; Conditioning, Operant; Discrimination, Psychological; Fluoxetine; Indans; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

1998