Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and tropisetron

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with tropisetron in 4 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(tropisetron)
Trials
(tropisetron)
Recent Studies (post-2010) (tropisetron)
218012944218150

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)tropisetron (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.1623
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.1623
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.45
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)1.8
Sodium-dependent serotonin transporterHomo sapiens (human)0.488
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)1.8

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN1
Fermanian, J; Frances, H; Lienard, C1
Bockaert, J; Dumuis, A; Sebben, M1
Curzon, G; Kennett, GA1

Other Studies

4 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and tropisetron

ArticleYear
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron

1992
Improvement of the isolation-induced social behavioural deficit involves activation of the 5-HT1B receptors.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:1

    Topics: Animals; Cyproheptadine; Escape Reaction; Indoles; Male; Mianserin; Mice; Mice, Inbred Strains; Penbutolol; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Social Behavior; Social Isolation; Spiperone; Tropisetron

1990
Pharmacological characterization of 5-hydroxytryptamine4(5-HT4) receptors positively coupled to adenylate cyclase in adult guinea pig hippocampal membranes: effect of substituted benzamide derivatives.
    Molecular pharmacology, 1990, Volume: 37, Issue:3

    Topics: Adenylyl Cyclases; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Activation; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Male; Receptors, Serotonin; Serotonin; Signal Transduction; Spiperone; Structure-Activity Relationship; Tropisetron

1990
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
    Psychopharmacology, 1988, Volume: 96, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron

1988