Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and oxymetazoline

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with oxymetazoline in 2 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(oxymetazoline)
Trials
(oxymetazoline)
Recent Studies (post-2010) (oxymetazoline)
218012738128159

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)oxymetazoline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.578
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.261
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.332
Alpha-2A adrenergic receptorHomo sapiens (human)0.023
Cytochrome P450 2D6Homo sapiens (human)0.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.273
Alpha-2C adrenergic receptorHomo sapiens (human)2.633
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0056
Alpha-1D adrenergic receptorHomo sapiens (human)2.844
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.285
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.578
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0056
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.056
5-hydroxytryptamine receptor 6Homo sapiens (human)1.67

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M1
Böing, C; Bühlen, M; Fink, K; Göthert, M1

Other Studies

2 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and oxymetazoline

ArticleYear
Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Platelets; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Naphthalenes; Oxymetazoline; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Tetrahydronaphthalenes; Yohimbine

1990
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines

1996