5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with mianserin in 10 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (mianserin) | Trials (mianserin) | Recent Studies (post-2010) (mianserin) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 2,624 | 539 | 488 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | mianserin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0012 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 1.4125 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.163 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.078 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.066 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.3981 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 1.9 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.32 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0213 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.423 | |
| D(2) dopamine receptor | Homo sapiens (human) | 7.0795 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.026 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0661 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.872 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.405 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.543 | |
| D(4) dopamine receptor | Homo sapiens (human) | 3.3113 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.38 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.163 | |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | 1.4125 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.008 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.083 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.1148 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3802 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.011 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0043 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.872 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.068 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 2.9 | |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | 0.1148 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.4074 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.21 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0024 | |
| D(3) dopamine receptor | Homo sapiens (human) | 3.8905 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0073 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.19 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 1.4125 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.88 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.085 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 3.5481 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 1.4125 | |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | 1.4125 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.022 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amlaiky, N; Boschert, U; Hen, R; Maroteaux, L; Plassat, JL; Saudou, F | 1 |
| Glennon, RA | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Fermanian, J; Frances, H; Lienard, C | 1 |
| Curzon, G; Kennett, GA | 1 |
| Peroutka, SJ | 1 |
| Blier, P; de Montigny, C; Piñeyro, G; Weiss, M | 1 |
1 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and mianserin
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
9 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and mianserin
| Article | Year |
|---|---|
Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.
Topics: 3T3 Cells; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Cerebellum; Corpus Striatum; Gene Expression; Genes; GTP-Binding Proteins; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Purkinje Cells; Receptors, Serotonin; RNA, Messenger; Serotonin | 1992 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Improvement of the isolation-induced social behavioural deficit involves activation of the 5-HT1B receptors.
Topics: Animals; Cyproheptadine; Escape Reaction; Indoles; Male; Mianserin; Mice; Mice, Inbred Strains; Penbutolol; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Social Behavior; Social Isolation; Spiperone; Tropisetron | 1990 |
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1988 |
Pharmacological differentiation and characterization of 5-HT1A, 5-HT1B, and 5-HT1C binding sites in rat frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Frontal Lobe; Indoles; Methysergide; Mianserin; Piperazines; Rats; Serotonin; Tetrahydronaphthalenes | 1986 |
Autoregulatory properties of dorsal raphe 5-HT neurons: possible role of electrotonic coupling and 5-HT1D receptors in the rat brain.
Topics: Action Potentials; Animals; Dendrites; Electric Stimulation; Electrophysiology; Extracellular Space; Indoles; Male; Mianserin; Piperazines; Propranolol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses | 1996 |