5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with methysergide in 12 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (methysergide) | Trials (methysergide) | Recent Studies (post-2010) (methysergide) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 2,935 | 81 | 80 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | methysergide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0021 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.631 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.807 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 4.763 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.054 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.943 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0021 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.054 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.172 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.162 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 10 (83.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN | 1 |
| Simansky, KJ | 1 |
| Danzebrink, RM; Gebhart, GF | 1 |
| Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M | 2 |
| Peroutka, SJ | 1 |
12 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and methysergide
| Article | Year |
|---|---|
Cloning and characterisation of the human 5-HT5A serotonin receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron | 1992 |
Peripheral 5-carboxamidotryptamine (5-CT) elicits drinking by stimulating 5-HT1-like serotonergic receptors in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Indoles; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tetrahydronaphthalenes | 1991 |
Intrathecal coadministration of clonidine with serotonin receptor agonists produces supra-additive visceral antinociception in the rat.
Topics: Amphetamines; Analgesics; Animals; Biogenic Monoamines; Clonidine; Dose-Response Relationship, Drug; Indoles; Injections, Spinal; Male; Methysergide; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Yohimbine | 1991 |
Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Platelets; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Naphthalenes; Oxymetazoline; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Tetrahydronaphthalenes; Yohimbine | 1990 |
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine | 1990 |
Pharmacological differentiation and characterization of 5-HT1A, 5-HT1B, and 5-HT1C binding sites in rat frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Frontal Lobe; Indoles; Methysergide; Mianserin; Piperazines; Rats; Serotonin; Tetrahydronaphthalenes | 1986 |