5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with methiothepin in 21 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (methiothepin) | Trials (methiothepin) | Recent Studies (post-2010) (methiothepin) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 494 | 2 | 62 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | methiothepin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | 0.0075 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 14 (66.67) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Hannon, S; Heal, DJ; Martin, KF; Phillips, I | 1 |
| Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN | 1 |
| Hjorth, S; Tao, R | 1 |
| Auerbach, SB; Kamalakannan, N; Rutter, JJ | 1 |
| Galzin, AM; Langer, SZ; Ramdine, R | 1 |
| Bom, AH; Saxena, PR; Verdouw, PD; Villalón, CM | 1 |
| Chaput, Y; de Montigny, C | 1 |
| Middlemiss, DN | 1 |
| Blier, P; Galzin, AM; Langer, SZ | 1 |
| Bonanno, G; Maura, G; Raiteri, M | 1 |
| Kruk, ZL; O'Connor, JJ | 1 |
| Böing, C; Bühlen, M; Fink, K; Göthert, M | 1 |
| Li, MY; Reith, ME | 1 |
| Hannon, SD; Martin, KF; Redfern, PH; Sayer, TJ | 1 |
21 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and methiothepin
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Cloning and characterisation of the human 5-HT5A serotonin receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo.
Topics: Animals; Dialysis; Dose-Response Relationship, Drug; Hippocampus; Indoles; Injections, Intraperitoneal; Male; Methiothepin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes | 1992 |
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron | 1992 |
The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969.
Topics: Animals; Brain Chemistry; Citalopram; Dialysis; Hippocampus; Indoles; Male; Methiothepin; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1991 |
TFMPP and RU24969 enhance serotonin release from rat hippocampus.
Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Hippocampus; Indicators and Reagents; Indoles; Male; Methiothepin; Piperazines; Potassium; Rats; Serotonin; Serotonin Antagonists | 1990 |
Phorbol-12,13-dibutyrate antagonizes while forskolin potentiates the presynaptic autoreceptor-mediated inhibition of [3H]-5-hydroxytryptamine release in rat hypothalamic slices.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Drug Interactions; Drug Synergism; Electric Stimulation; Evoked Potentials; Hypothalamus; Indoles; Male; Methiothepin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Rats; Rats, Inbred Strains; Serotonin | 1989 |
The 5-HT1-like receptor mediating reduction of porcine carotid arteriovenous shunting by RU 24969 is not related to either the 5-HT1A or the 5-HT1B subtype.
Topics: Animals; Blood Pressure; Carotid Arteries; Heart Rate; Hemodynamics; Indoles; Ketanserin; Methiothepin; Microspheres; Pindolol; Receptors, Serotonin; Swine | 1989 |
Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Electrophysiology; Indoles; Male; Methiothepin; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tetrahydronaphthalenes | 1988 |
The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor.
Topics: Animals; Cerebral Cortex; Dioxanes; Idazoxan; In Vitro Techniques; Indoles; Male; Methiothepin; Potassium; Propranolol; Quipazine; Rats; Receptors, Serotonin; Serotonin | 1985 |
Diurnal variation in the function of serotonin terminals in the rat hypothalamus.
Topics: 5-Methoxytryptamine; Animals; Carrier Proteins; Circadian Rhythm; Citalopram; Electric Stimulation; Fenfluramine; Hypothalamus; Indoles; Male; Methiothepin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1989 |
Pharmacological characterization of release-regulating serotonin autoreceptors in rat cerebellum.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebellum; In Vitro Techniques; Indoles; Male; Methiothepin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptosomes; Tetrahydronaphthalenes | 1986 |
Effects of 21 days treatment with fluoxetine on stimulated endogenous 5-hydroxytryptamine overflow in the rat dorsal raphe and suprachiasmatic nucleus studied using fast cyclic voltammetry in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Electric Stimulation; Electrophysiology; Fluoxetine; In Vitro Techniques; Indoles; Male; Methiothepin; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 1994 |
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines | 1996 |
Effect of quinine on autoreceptor-regulated serotonin release in the rat hippocampus.
Topics: Animals; Autoreceptors; Chromatography, High Pressure Liquid; Fluoxetine; Hippocampus; Indoles; Male; Methiothepin; Microdialysis; Potassium Channels; Quinine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin | 1997 |
Diurnal variation in 5-HT1B autoreceptor function in the anterior hypothalamus in vivo: effect of chronic antidepressant drug treatment.
Topics: Adrenergic Uptake Inhibitors; Animals; Autoreceptors; Circadian Rhythm; Desipramine; Hypothalamus, Anterior; Indoles; Male; Methiothepin; Microdialysis; Paroxetine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |