5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with metergoline in 14 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (metergoline) | Trials (metergoline) | Recent Studies (post-2010) (metergoline) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 656 | 37 | 44 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | metergoline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0007 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.366 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0041 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.058 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.063 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.016 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.189 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0062 | |
| Substance-K receptor | Homo sapiens (human) | 4.071 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.074 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.344 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.366 | |
| Histamine H2 receptor | Homo sapiens (human) | 0.975 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.136 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0004 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0007 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0062 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.59 | |
| Histamine H1 receptor | Homo sapiens (human) | 4.133 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0077 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0004 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.028 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.063 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Glennon, RA | 1 |
| Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Murphy, AZ; Murphy, RM; Zemlan, FP | 1 |
| Eide, PK; Hole, K | 1 |
| Brazell, MP; Marsden, CA; Nisbet, AP; Routledge, C | 1 |
| Appel, JB; Cunningham, KA | 1 |
| Bockaert, J; Kemp, DE; Sebben, M; Weiss, S | 1 |
| Marsden, CA; Martin, KF; Webb, AR | 1 |
| Evenden, JL | 1 |
1 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and metergoline
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
13 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and metergoline
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Cloning and characterisation of the human 5-HT5A serotonin receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Role of spinal serotonin1 receptor subtypes in thermally and mechanically elicited nociceptive reflexes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hot Temperature; Indoles; Male; Metergoline; Nociceptors; Physical Stimulation; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Reflex; Spinal Cord | 1992 |
Interactions between serotonin and substance P in the spinal regulation of nociception.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Indoles; Injections, Spinal; Male; Metergoline; Mice; Mice, Inbred Strains; Neurons; Pain; Serotonin; Serotonin Antagonists; Skin Temperature; Spinal Cord; Substance P; Tetrahydronaphthalenes | 1991 |
The 5-HT1 receptor agonist RU-24969 decreases 5-hydroxytryptamine (5-HT) release and metabolism in the rat frontal cortex in vitro and in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Dialysis; Electrochemistry; Frontal Lobe; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Male; Metergoline; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Time Factors | 1985 |
Possible 5-hydroxytryptamine1 (5-HT1) receptor involvement in the stimulus properties of 1-(m-trifluoromethylphenyl)piperazine (TFMPP).
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Indoles; Lysergic Acid Diethylamide; Male; Metergoline; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1986 |
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; Fetus; Indoles; Ketanserin; Metergoline; Mice; Neurons; Piperidines; Pregnancy; Receptors, Serotonin; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide | 1986 |
The behavioural response to the 5-hydroxytryptamine1B (5HT1B) receptor agonist--RU-24969 may exhibit a circadian variation in the mouse.
Topics: Animals; Circadian Rhythm; Drug Administration Schedule; Indoles; Male; Metergoline; Mice; Motor Activity | 1987 |
The pharmacology of impulsive behaviour in rats IV: the effects of selective serotonergic agents on a paced fixed consecutive number schedule.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Impulsive Behavior; Indoles; Male; Metergoline; p-Chloroamphetamine; Rats; Reinforcement, Psychology; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 1998 |