Compounds > 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and mesulergine

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with mesulergine in 7 studies

Compound Research Comparison

Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Studies (mesulergine)	Trials (mesulergine)	Recent Studies (post-2010) (mesulergine)
218	0	12	265	10	28

Protein Interaction Comparison

Protein	Taxonomy	5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)	mesulergine (IC50)
5-hydroxytryptamine receptor 2C	Homo sapiens (human)		0.0019
5-hydroxytryptamine receptor 7	Homo sapiens (human)		0.205
5-hydroxytryptamine receptor 3A	Rattus norvegicus (Norway rat)		0.0021
5-hydroxytryptamine receptor 2B	Homo sapiens (human)		0.0052
5-hydroxytryptamine receptor 3B	Rattus norvegicus (Norway rat)		0.0021

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (42.86)	18.7374
1990's	3 (42.86)	18.2507
2000's	1 (14.29)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Glennon, RA	1
Amlaiky, N; Hen, R; Plassat, JL	1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB	1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR	1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D	1
Curzon, G; Kennett, GA	1
Huang, JC; Peroutka, SJ	1

Reviews

1 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and mesulergine

Article	Year
Central serotonin receptors as targets for drug research. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin	1987

Other Studies

6 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and mesulergine

Article	Year
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular pharmacology, 1993, Volume: 44, Issue:2 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature	1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity	1996
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2004
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors. Psychopharmacology, 1988, Volume: 96, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron	1988
Identification of 5-hydroxytryptamine binding site subtypes in rat spinal cord. Brain research, 1987, Dec-08, Volume: 436, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Ergolines; In Vitro Techniques; Indoles; Rats; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes	1987