5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with ketanserin in 18 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (ketanserin) | Trials (ketanserin) | Recent Studies (post-2010) (ketanserin) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 3,094 | 335 | 283 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | ketanserin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0016 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0021 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.265 | |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 6.5 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0184 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0027 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0016 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.29 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 1.8 | |
| Synaptic vesicular amine transporter | Homo sapiens (human) | 0.18 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 10 (55.56) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amlaiky, N; Boschert, U; Hen, R; Maroteaux, L; Plassat, JL; Saudou, F | 1 |
| Glennon, RA | 1 |
| Buckingham, J; Glen, RC; Hill, AP; Hyde, RM; Martin, GR; Robertson, AD; Salmon, JA; Woollard, PM | 1 |
| Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN | 1 |
| Hollingsworth, PJ; Smith, CB; Walker, EA; Woods, JH; Yamamoto, T | 1 |
| Broekkamp, CL; Jenck, F; Van Delft, AM | 1 |
| Bom, AH; Saxena, PR; Verdouw, PD; Villalón, CM | 1 |
| el-Yassir, N; Fleetwood-Walker, SM; Mitchell, R | 1 |
| Bockaert, J; Kemp, DE; Sebben, M; Weiss, S | 1 |
| Laguzzi, R; Shvaloff, A | 1 |
| Curzon, G; Dourish, CT; Kennett, GA | 1 |
| Glennon, RA; McKenney, JD; Young, R | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Böing, C; Bühlen, M; Fink, K; Göthert, M | 1 |
1 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and ketanserin
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
17 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and ketanserin
| Article | Year |
|---|---|
Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.
Topics: 3T3 Cells; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Cerebellum; Corpus Striatum; Gene Expression; Genes; GTP-Binding Proteins; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Purkinje Cells; Receptors, Serotonin; RNA, Messenger; Serotonin | 1992 |
Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties.
Topics: Animals; Aorta; Computer-Aided Design; Drug Design; Haplorhini; In Vitro Techniques; Migraine Disorders; Models, Chemical; Rabbits; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Saphenous Vein; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines | 1995 |
Cloning and characterisation of the human 5-HT5A serotonin receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron | 1992 |
Discriminative-stimulus effects of quipazine and l-5-hydroxytryptophan in relation to serotonin binding sites in the pigeon.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Binding Sites; Binding, Competitive; Brain; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Indoles; Ketanserin; Kinetics; Male; Pyrimidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Tritium | 1991 |
5-HT1C receptors in the serotonergic control of periaqueductal gray induced aversion in rats.
Topics: Amphetamines; Animals; Cyproheptadine; Indoles; Ketanserin; Male; Periaqueductal Gray; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement, Psychology; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
The 5-HT1-like receptor mediating reduction of porcine carotid arteriovenous shunting by RU 24969 is not related to either the 5-HT1A or the 5-HT1B subtype.
Topics: Animals; Blood Pressure; Carotid Arteries; Heart Rate; Hemodynamics; Indoles; Ketanserin; Methiothepin; Microspheres; Pindolol; Receptors, Serotonin; Swine | 1989 |
Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Indoles; Ketanserin; Male; Neurons, Afferent; Pain; Physical Stimulation; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes | 1988 |
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; Fetus; Indoles; Ketanserin; Metergoline; Mice; Neurons; Piperidines; Pregnancy; Receptors, Serotonin; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide | 1986 |
Serotonin receptors in the rat nucleus tractus solitarii and cardiovascular regulation.
Topics: Animals; Blood Pressure; Body Temperature; Cardiovascular Physiological Phenomena; Heart Rate; Indoles; Ketanserin; Male; Medulla Oblongata; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists | 1986 |
5-HT1B agonists induce anorexia at a postsynaptic site.
Topics: Animals; Appetite Depressants; Haloperidol; Indoles; Ketanserin; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synapses | 1987 |
Discriminative stimulus properties of the serotonin agonist 1-(3-trifluoromethylphenyl)piperazine (TFMPP).
Topics: Animals; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Extinction, Psychological; Fenfluramine; Indoles; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines | 1996 |