Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and idazoxan

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with idazoxan in 4 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(idazoxan)
Trials
(idazoxan)
Recent Studies (post-2010) (idazoxan)
2180121,49940123

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blier, P; Chodkiewicz, JP; Galzin, AM; Langer, SZ; Lista, A; LoƓ, H; Poirier, MF; Ramdine, R; Redondo, A; Roux, FX1
Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M1
Berthold, H; Engel, G; Fozard, JR1
Middlemiss, DN1

Other Studies

4 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and idazoxan

ArticleYear
Characterization of the 5-hydroxytryptamine receptor modulating the release of 5-[3H]hydroxytryptamine in slices of the human neocortex.
    Journal of neurochemistry, 1992, Volume: 59, Issue:4

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Animals; Cerebral Cortex; Child; Dioxanes; Electric Stimulation; Female; Humans; Idazoxan; In Vitro Techniques; Indoles; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium; Yohimbine

1992
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine

1990
5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Buspirone; Dioxanes; Female; Fenclonine; Idazoxan; Indoles; Mice; Morphine Dependence; Naloxone; Prazosin; Receptors, Serotonin; Tetrahydronaphthalenes

1989
The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:6

    Topics: Animals; Cerebral Cortex; Dioxanes; Idazoxan; In Vitro Techniques; Indoles; Male; Methiothepin; Potassium; Propranolol; Quipazine; Rats; Receptors, Serotonin; Serotonin

1985