Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and ergotamine

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with ergotamine in 4 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(ergotamine)
Trials
(ergotamine)
Recent Studies (post-2010) (ergotamine)
2180122,352103103

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)ergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.056
Tyrosine-protein kinase LckHomo sapiens (human)6.499
Tyrosine-protein kinase FynHomo sapiens (human)3.16
Beta-2 adrenergic receptorHomo sapiens (human)2.761
Beta-1 adrenergic receptorHomo sapiens (human)4.142
Cytochrome P450 3A4Homo sapiens (human)1
Alpha-2A adrenergic receptorHomo sapiens (human)0.0021
D(2) dopamine receptorHomo sapiens (human)0.0043
Alpha-2B adrenergic receptorHomo sapiens (human)0.0038
Alpha-2C adrenergic receptorHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0008
D(1A) dopamine receptorHomo sapiens (human)1.728
Thromboxane-A synthase Homo sapiens (human)3.064
Alpha-1D adrenergic receptorHomo sapiens (human)0.049
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0065
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.056
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0008
D(3) dopamine receptorHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0035
5-hydroxytryptamine receptor 6Homo sapiens (human)0.002

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S1
Amlaiky, N; Hen, R; Plassat, JL1
Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1

Other Studies

4 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and ergotamine

ArticleYear
Cloning and characterisation of the human 5-HT5A serotonin receptor.
    FEBS letters, 1994, Dec-05, Volume: 355, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection

1994
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists

1993
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004