Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and cyproheptadine

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with cyproheptadine in 3 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(cyproheptadine)
Trials
(cyproheptadine)
Recent Studies (post-2010) (cyproheptadine)
2180122,297262201

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)cyproheptadine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0024
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.564
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.035
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.016
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0031
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0038
Alpha-2A adrenergic receptorHomo sapiens (human)0.283
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.016
D(2) dopamine receptorHomo sapiens (human)0.164
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0031
Alpha-2B adrenergic receptorHomo sapiens (human)0.038
Alpha-2C adrenergic receptorHomo sapiens (human)1.275
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.122
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.046
D(1A) dopamine receptorHomo sapiens (human)0.158
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.564
Histamine H2 receptorHomo sapiens (human)0.198
Alpha-1D adrenergic receptorHomo sapiens (human)0.107
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.001
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0024
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.122
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0031
Histamine H1 receptorHomo sapiens (human)0.0037
D(3) dopamine receptorHomo sapiens (human)0.048
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0094
5-hydroxytryptamine receptor 6Homo sapiens (human)0.281
D(2) dopamine receptorRattus norvegicus (Norway rat)0.14
Histone-lysine N-methyltransferase SETD7Homo sapiens (human)2.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Broekkamp, CL; Jenck, F; Van Delft, AM1
Fermanian, J; Frances, H; Lienard, C1

Other Studies

3 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and cyproheptadine

ArticleYear
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
5-HT1C receptors in the serotonergic control of periaqueductal gray induced aversion in rats.
    Psychopharmacology, 1990, Volume: 100, Issue:3

    Topics: Amphetamines; Animals; Cyproheptadine; Indoles; Ketanserin; Male; Periaqueductal Gray; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement, Psychology; Ritanserin; Serotonin; Serotonin Antagonists

1990
Improvement of the isolation-induced social behavioural deficit involves activation of the 5-HT1B receptors.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:1

    Topics: Animals; Cyproheptadine; Escape Reaction; Indoles; Male; Mianserin; Mice; Mice, Inbred Strains; Penbutolol; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Social Behavior; Social Isolation; Spiperone; Tropisetron

1990