Page last updated: 2024-09-02

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and citalopram

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with citalopram in 6 studies

Compound Research Comparison

Studies
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Trials
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Recent Studies (post-2010)
(5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
Studies
(citalopram)
Trials
(citalopram)
Recent Studies (post-2010) (citalopram)
2180125,3481,4242,350

Protein Interaction Comparison

ProteinTaxonomy5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)citalopram (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.196
AromataseRattus norvegicus (Norway rat)0.0018
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.196
Alpha-1D adrenergic receptorHomo sapiens (human)3.289
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
Sodium-dependent serotonin transporterHomo sapiens (human)0.0227
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.0027
Histamine H1 receptorHomo sapiens (human)3.194
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.839
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.1869
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.398
TransporterRattus norvegicus (Norway rat)8.8

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Hjorth, S; Tao, R1
Blier, P; Galzin, AM; Langer, SZ1
Bonanno, G; Raiteri, M1
Auerbach, SB; Hjorth, S1
Evenden, JL1

Other Studies

6 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and citalopram

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969.
    European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3

    Topics: Animals; Brain Chemistry; Citalopram; Dialysis; Hippocampus; Indoles; Male; Methiothepin; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1991
Diurnal variation in the function of serotonin terminals in the rat hypothalamus.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: 5-Methoxytryptamine; Animals; Carrier Proteins; Circadian Rhythm; Citalopram; Electric Stimulation; Fenfluramine; Hypothalamus; Indoles; Male; Methiothepin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1989
Interaction between 5-HT uptake inhibition and activation of 5-HT autoreceptors by exogenous agonists in rat cerebral cortex slices and synaptosomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:3

    Topics: Animals; Calcium; Cerebral Cortex; Citalopram; Electric Stimulation; In Vitro Techniques; Indoles; Male; Potassium Chloride; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptosomes; Tetrodotoxin

1987
Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:6

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Autoreceptors; Citalopram; Dialysis; Drug Tolerance; Indoles; Infusions, Intravenous; Male; Prosencephalon; Pyridines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

1995
The pharmacology of impulsive behaviour in rats IV: the effects of selective serotonergic agents on a paced fixed consecutive number schedule.
    Psychopharmacology, 1998, Volume: 140, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Impulsive Behavior; Indoles; Male; Metergoline; p-Chloroamphetamine; Rats; Reinforcement, Psychology; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes

1998