5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with cgs 12066 in 4 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (cgs 12066) | Trials (cgs 12066) | Recent Studies (post-2010) (cgs 12066) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 22 | 0 | 8 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | cgs 12066 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 1.3183 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 1.3183 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0468 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 6.8 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 6.8 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.035 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.2759 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 6.8 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 1.3183 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 1.3183 | |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | 0.123 | |
| Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | 0.0468 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 1.3183 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 1.3183 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 1.3183 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Burkhart, CA; Heym, JH; Ives, JL; Lebel, LA; Macor, JE; Newman, ME; Nielsen, JA; Ryan, K; Schulz, DW; Torgersen, LK | 1 |
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
4 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and cgs 12066
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.
Topics: Adenylyl Cyclase Inhibitors; Animals; Chemical Phenomena; Chemistry; Colforsin; Cyclization; Eating; Guinea Pigs; Hippocampus; Indoles; Molecular Structure; Paraventricular Hypothalamic Nucleus; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Serotonin; Substantia Nigra | 1990 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |