5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with amitriptyline in 3 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (amitriptyline) | Trials (amitriptyline) | Recent Studies (post-2010) (amitriptyline) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 6,935 | 1,381 | 1,060 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | amitriptyline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.006 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.023 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.081 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0053 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.3 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.044 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.008 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.1755 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.011 | |
| D(2) dopamine receptor | Homo sapiens (human) | 1.009 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.044 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.004 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0295 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 1.02 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.026 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.355 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.0324 | |
| Histamine H2 receptor | Homo sapiens (human) | 0.73 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.105 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.015 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.006 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 1.02 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.044 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.2756 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.044 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0048 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.182 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.07 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.66 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.14 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 7.2446 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 1.6 | |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | 4 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.044 | |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | 3.1 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.031 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.044 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Marsden, CA; Palfreyman, MG; Sleight, AJ; Smith, RJ | 1 |
3 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and amitriptyline
| Article | Year |
|---|---|
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
The effects of chronic treatment with amitriptyline and MDL 72394 on the control of 5-HT release in vivo.
Topics: Amitriptyline; Animals; Brain; Dialysis; Indoles; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Tyrosine | 1989 |