5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and 8-hydroxy-2-(di-n-propylamino)tetralin

5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 94 studies

Compound Research Comparison

Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Studies (8-hydroxy-2-(di-n-propylamino)tetralin)	Trials (8-hydroxy-2-(di-n-propylamino)tetralin)	Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
218	0	12	3,530	7	389

Protein Interaction Comparison

Protein	Taxonomy	8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	0.0012
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0032
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Bos taurus (cattle)	0.8
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	2.8959
Lysosomal alpha-glucosidase	Bos taurus (cattle)	0.0021

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (42.55)	18.7374
1990's	45 (47.87)	18.2507
2000's	7 (7.45)	29.6817
2010's	2 (2.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Glennon, RA	1
Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S	1
Amlaiky, N; Hen, R; Plassat, JL	1
Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL	1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D	1
Barrett, JE; Gleeson, S; Seggel, MR; Weissman, BA	1
Eide, PK; Lund, A; Mjellem, N; Størkson, R; Tjølsen, A	1
Eide, PK	1
Coscina, DV; Fletcher, PJ; Ming, ZH; Zack, MH	1
Dick, H; Goodwin, GM; MacDonald, LM; St John, H; Young, AH	1
Dzoljic, MR; Saxena, PR; Ukponmwan, OE	1
Murphy, AZ; Murphy, RM; Zemlan, FP	1
Barrett, JE; Gleeson, S	1
Pranzatelli, MR	1
Mos, J; Olivier, B; Slangen, JL; Ybema, CE	1
Cannon, JG; Long, JP; Park, KH	1
Eide, PK; Hole, K	1
Simansky, KJ	1
Schwab, EF; Zemlan, FP	1
Curzon, G	1
Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M	2
Blier, P; Scatton, B; Serrano, A	1
Lucot, JB	1
Cherqui, C; Dabire, H; Schmitt, H	1
Simansky, KJ; Vaidya, AH	1
Eide, PK; Hole, K; Joly, NM	1
Marsden, CA; Routledge, C	1
Bramwell, SR; Grahame-Smith, DG; Sharp, T	1
Amoroso, S; Annunziato, L; Basile, V; Canzoniero, L; Di Renzo, G; Fatatis, A; Taglialatela, M	1
Bethea, CL; Lorens, SA; Urban, JH; Van de Kar, LD	1
Dugovic, C; Janssen, PA; Leysen, JE; Marrannes, R; Wauquier, A	1
Jackson, HC; Kitchen, I	1
Fedele, E; Maura, G; Raiteri, M	1
Cheetham, SC; Horton, RW; Yamaguchi, Y	1
Berendsen, HH; Broekkamp, CL; Jenck, F	1
Berthold, H; Engel, G; Fozard, JR	1
Goodwin, GM; Green, AR	1
Chaput, Y; de Montigny, C	1
Bonanno, G; Maura, G; Pittaluga, A; Raiteri, M	1
Curzon, G; Dourish, CT; Kennett, GA	1
Gardner, CR	1
Bonanno, G; Maura, G; Pittaluga, A; Raiteri, M; Ulivi, M	1
Appel, JB; Cunningham, KA	1
Heuring, RE; Peroutka, SJ; Schlegel, JR	1
De Vivo, M; Maayani, S	1
De Souza, RJ; Goodwin, GM; Green, AR	1
Peroutka, SJ	1
Frances, H; Simon, P	1
Bonanno, G; Maura, G; Raiteri, M	1
De Souza, RJ; Goodwin, GM; Green, AR; Heal, DJ	1
De Souza, RJ; Goodwin, GM; Green, AR; Wood, AJ	1
Balestre, MN; Bockaert, J; Cory, RN; Guillon, G; Rouot, B; Sladeczek, F	1
Bendotti, C; Samanin, R	1
Dugovic, C; Wauquier, A	1
Petti, DT; Winter, JC	1
Huang, JC; Peroutka, SJ	1
Moser, PC; Redfern, PH	1
Davis, CJ; Goodwin, GM; Kelly, PA	1
el-Yassir, N; Fleetwood-Walker, SM; Mitchell, R	1
Heal, DJ; Smith, SL	1
Bockaert, J; Kemp, DE; Sebben, M; Weiss, S	1
DeSouza, RJ; Goodwin, GM; Green, AR; Wood, AJ	1
De Jonge, A; Doods, HN; Kalkman, HO; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B	1
Blackburn, TP; Cox, B; Kemp, JD; Martin, DA	1
Cortés, R; Palacios, JM; Pazos, A	1
Bosker, FJ; Klompmakers, AA; van Esseveldt, KE; Westenberg, HG	1
Boulenguez, P; Buhot, MC; Chauveau, J; Foreman, N; Segu, L	1
Bovetto, S; Richard, D	1
Kruk, ZL; O'Connor, JJ	1
Leysen, JE; Pauwels, PJ; Van Gompel, P	1
Korneyev, AY; Seredenin, SB	1
Frölich, D; Göthert, M; Likungu, J; Molderings, GJ	1
Bourin, M; MacSweeney, CP; Redrobe, JP	1
Bosker, F; Klompmakers, A; Vrinten, D; Westenberg, H	1
Herremans, AH; Mos, J; Olivier, B; Van Drimmelen, M; Van Hest, A	1
Dulawa, SC; Geyer, MA; Hen, R; Scearce-Levie, K	1
O'Neill, MF; Parameswaran, T	1
Cook, DF; Wirtshafter, D	1
Koob, GF; Parsons, LH; Weiss, F	1
Evenden, JL	1
Baker, GB; Bourin, M; Colombel, MC; Redrobe, JP	1
Fletcher, PJ; Korth, KM	1
Dulawa, SC; Geyer, MA; Gross, C; Hen, R; Stark, KL	1
Conway, MW; O'Neill, MF	1
Yan, QS; Yan, SE	1
Geyer, MA; Martinez-Price, DL	1
Ansorge, M; Dulawa, SC; Geyer, MA; Gingrich, JA; Hen, R; Holick Pierz, KA; Masten, VL; Shanahan, NA; Waeber, C	1
Belzung, C; Chapouthier, G; Clément, Y; Le Guisquet, AM; Venault, P	1
Dulawa, SC; Masten, VL; Shanahan, NA; Velez, LP	1
Aronsen, D; Schenk, S	1

Reviews

3 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Central serotonin receptors as targets for drug research. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin	1987
Effects of tryptophan and of 5-hydroxytryptamine receptor subtype agonists on feeding. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite; Brain; Dietary Carbohydrates; Feeding Behavior; Female; Food Deprivation; Food Preferences; Humans; Indoles; Male; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sex Factors; Tetrahydronaphthalenes; Tryptophan	1991
Potential use of drugs modulating 5HT activity in the treatment of anxiety. General pharmacology, 1988, Volume: 19, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Humans; Imidazoles; Indoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1988

Other Studies

91 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Cloning and characterisation of the human 5-HT5A serotonin receptor. FEBS letters, 1994, Dec-05, Volume: 355, Issue:3 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection	1994
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular pharmacology, 1993, Volume: 44, Issue:2 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists	1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature	1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2004
Neurochemical effects of 5-HT1 receptor ligands in pigeons. European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Columbidae; Hydroxyindoleacetic Acid; Indoles; Male; Methoxyhydroxyphenylglycol; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1992
The role of 5-HT1A and 5-HT1B receptors in spinal nociceptive transmission and in the modulation of NMDA induced behaviour. Neuroreport, 1992, Volume: 3, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hot Temperature; Indoles; Injections, Spinal; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Skin Temperature; Spinal Cord; Synaptic Transmission	1992
Stimulation of 5-HT1 receptors in the spinal cord changes substance P-induced behaviour. Neuropharmacology, 1992, Volume: 31, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesia; Animals; Indoles; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurons; Pain; Piperazines; Quipazine; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotyped Behavior; Substance P	1992
A comparison of the effects of the 5-HT1 agonists TFMPP and RU 24969 on feeding following peripheral or medial hypothalamic injection. Brain research, 1992, May-15, Volume: 580, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Eating; Food Deprivation; Hypothalamus, Middle; Indoles; Male; Microinjections; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1992
The effects of corticosterone on 5-HT receptor function in rodents. Neuropharmacology, 1992, Volume: 31, Issue:5 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Corticosterone; Indoles; Male; Methoxydimethyltryptamines; Mice; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes; Weight Gain	1992
5-HT1-like receptor agonists enhance wakefulness. Neuropharmacology, 1992, Volume: 31, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sleep; Sleep, REM; Wakefulness	1992
Role of spinal serotonin1 receptor subtypes in thermally and mechanically elicited nociceptive reflexes. Psychopharmacology, 1992, Volume: 108, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hot Temperature; Indoles; Male; Metergoline; Nociceptors; Physical Stimulation; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Reflex; Spinal Cord	1992
Discriminative stimulus effects of 8-OH-DPAT in pigeons: antagonism studies with the putative 5-HT1A receptor antagonists BMY 7378 and NAN-190. European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Indoles; Pindolol; Piperazines; Prazosin; Serotonin Antagonists	1992
Serotonin receptor ontogeny: effects of agonists in 1-day-old rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals, Newborn; Female; Indoles; Pregnancy; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1992
Discriminative stimulus properties of the serotonergic compound eltoprazine. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dose-Response Relationship, Drug; Generalization, Stimulus; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1992
Effects of serotonin1-like receptor agonists on autonomic neurotransmission. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aporphines; Autonomic Nervous System; Bretylium Compounds; Cats; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Indoles; Male; Nictitating Membrane; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tetrahydronaphthalenes	1991
Interactions between serotonin and substance P in the spinal regulation of nociception. Brain research, 1991, Jun-07, Volume: 550, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Indoles; Injections, Spinal; Male; Metergoline; Mice; Mice, Inbred Strains; Neurons; Pain; Serotonin; Serotonin Antagonists; Skin Temperature; Spinal Cord; Substance P; Tetrahydronaphthalenes	1991
Peripheral 5-carboxamidotryptamine (5-CT) elicits drinking by stimulating 5-HT1-like serotonergic receptors in rats. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Indoles; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tetrahydronaphthalenes	1991
Characterization of a novel serotonin receptor subtype (5-HT1S) in rat CNS: interaction with a GTP binding protein. Journal of neurochemistry, 1991, Volume: 57, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; GTP-Binding Proteins; Indoles; Male; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spinal Cord; Tetrahydronaphthalenes; Tissue Distribution	1991
Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide. British journal of pharmacology, 1990, Volume: 99, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Platelets; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Naphthalenes; Oxymetazoline; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Tetrahydronaphthalenes; Yohimbine	1990
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain. British journal of pharmacology, 1990, Volume: 99, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine	1990
Differential responsiveness of the rat dorsal and median raphe 5-HT systems to 5-HT1 receptor agonists and p-chloroamphetamine. Synapse (New York, N.Y.), 1990, Volume: 5, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Indoles; Male; Naphthalenes; p-Chloroamphetamine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1990
RU 24969-induced emesis in the cat: 5-HT1 sites other than 5-HT1A, 5-HT1B or 5-HT1C implicated. European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Dose-Response Relationship, Drug; Drug Interactions; Emetics; Female; Indoles; Injections, Subcutaneous; Piperazines; Receptors, Histamine H1; Tetrahydronaphthalenes	1990
[Hemodynamic profile of 8-OH-DPAT and 5-HT1 agonists in the anesthetized dog]. Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Anesthesia, General; Animals; Dogs; Hemodynamics; Indoles; Methoxydimethyltryptamines; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1990
Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonists. Brain research bulletin, 1990, Volume: 25, Issue:6 Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Appetite; Eating; Feeding Behavior; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Satiation; Sertraline; Tetrahydronaphthalenes	1990
The role of spinal cord 5-HT1A and 5-HT1B receptors in the modulation of a spinal nociceptive reflex. Brain research, 1990, Dec-17, Volume: 536, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Indoles; Injections, Spinal; Male; Methoxydimethyltryptamines; Mice; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Serotonin; Reflex; Serotonin Antagonists; Skin Temperature; Spinal Cord; Tetrahydronaphthalenes	1990
Recent advances in high-performance liquid chromatographic analysis of small molecules. Application of high-performance liquid chromatography with electrochemical detection to the study of neurotransmitters in vivo. Biochemical Society transactions, 1985, Volume: 13, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cerebral Ventricles; Chromatography, High Pressure Liquid; Corpus Striatum; Electric Stimulation; Epinephrine; Extracellular Space; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Medulla Oblongata; Phenylacetates; Rats; Serotonin; Tetrahydronaphthalenes	1985
5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Indoles; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes	1989
Pharmacological characterization of serotonin receptors involved in the control of prolactin secretion. European journal of pharmacology, 1989, Mar-21, Volume: 162, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Fenfluramine; Indoles; Male; Piperidines; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes	1989
Effect of selective serotonin (5-HT) agonists and 5-HT2 antagonist on prolactin secretion. Neuropharmacology, 1989, Volume: 28, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ergolines; Fenfluramine; Indoles; Male; Prolactin; Pyrazines; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1989
Functional role of 5-HT2 receptors in the regulation of sleep and wakefulness in the rat. Psychopharmacology, 1989, Volume: 97, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cinanserin; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Indoles; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Sleep; Tetrahydronaphthalenes; Wakefulness	1989
Behavioural profiles of putative 5-hydroxytryptamine receptor agonists and antagonists in developing rats. Neuropharmacology, 1989, Volume: 28, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Grooming; Indoles; Male; Methoxydimethyltryptamines; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Tetrahydronaphthalenes	1989
Acetylcholine release from rat hippocampal slices is modulated by 5-hydroxytryptamine. European journal of pharmacology, 1989, Jun-20, Volume: 165, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Electric Stimulation; Fenfluramine; Hippocampus; In Vitro Techniques; Indoles; Male; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1989
[3H]5-hydroxytryptamine binding sites in postmortem human brain. Neuropharmacology, 1989, Volume: 28, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Hippocampus; Humans; In Vitro Techniques; Indoles; Kinetics; Male; Membranes; Middle Aged; Postmortem Changes; Receptors, Serotonin; Tetrahydronaphthalenes	1989
Selective activation of 5HT1A receptors induces lower lip retraction in the rat. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Dose-Response Relationship, Drug; Indoles; Lip; Male; Muscles; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1989
5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice. European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Buspirone; Dioxanes; Female; Fenclonine; Idazoxan; Indoles; Mice; Morphine Dependence; Naloxone; Prazosin; Receptors, Serotonin; Tetrahydronaphthalenes	1989
A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5-HT1 and 5-HT2 receptors. British journal of pharmacology, 1985, Volume: 84, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Body Temperature; Brain Chemistry; Histamine H2 Antagonists; Hydroxyindoleacetic Acid; Indoles; Kinetics; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes	1985
Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Electrophysiology; Indoles; Male; Methiothepin; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tetrahydronaphthalenes	1988
Differential pharmacology and function of two 5-HT1 receptors modulating transmitter release in rat cerebellum. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebellum; Glutamates; Glutamic Acid; In Vitro Techniques; Indoles; Male; Neurotransmitter Agents; Potassium; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1986
Antidepressant-like action of 5-HT1A agonists and conventional antidepressants in an animal model of depression. European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Buspirone; Depressive Disorder; Disease Models, Animal; Drug Interactions; Indoles; Male; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin; Stress, Psychological; Tetrahydronaphthalenes	1987
Serotonin-glutamate interaction in rat cerebellum: involvement of 5-hydroxytryptamine receptor subtypes. Annali dell'Istituto superiore di sanita, 1988, Volume: 24, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebellum; Glutamates; Glutamic Acid; Indoles; Male; Naphthalenes; Nerve Endings; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1988
Possible 5-hydroxytryptamine1 (5-HT1) receptor involvement in the stimulus properties of 1-(m-trifluoromethylphenyl)piperazine (TFMPP). The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Indoles; Lysergic Acid Diethylamide; Male; Metergoline; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes	1986
Species variations in RU 24969 interactions with non-5-HT1A binding sites. European journal of pharmacology, 1986, Mar-18, Volume: 122, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain Chemistry; Cattle; Chickens; Dogs; Guinea Pigs; Humans; Indoles; Kinetics; Mice; Mice, Inbred BALB C; Rana pipiens; Rats; Rats, Inbred Strains; Receptors, Serotonin; Species Specificity; Tetrahydronaphthalenes; Turtles	1986
Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Buspirone; Colforsin; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; Indoles; Lisuride; Mathematics; Pyrimidines; Rats; Receptors, Serotonin; Tetrahydronaphthalenes	1986
The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats. Psychopharmacology, 1986, Volume: 89, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Indoles; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Tetrahydronaphthalenes	1986
Pharmacological differentiation and characterization of 5-HT1A, 5-HT1B, and 5-HT1C binding sites in rat frontal cortex. Journal of neurochemistry, 1986, Volume: 47, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Frontal Lobe; Indoles; Methysergide; Mianserin; Piperazines; Rats; Serotonin; Tetrahydronaphthalenes	1986
The effect of a beta-adrenergic agonist on behaviors mediated by 5-HT1A and 5-HT1B receptors. Biological psychiatry, 1986, Volume: 21, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Clenbuterol; Drug Interactions; Ethanolamines; Indoles; Mice; Motor Activity; Naphthalenes; Receptors, Serotonin; Tetrahydronaphthalenes	1986
Pharmacological characterization of release-regulating serotonin autoreceptors in rat cerebellum. European journal of pharmacology, 1986, Jul-31, Volume: 126, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebellum; In Vitro Techniques; Indoles; Male; Methiothepin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synaptosomes; Tetrahydronaphthalenes	1986
Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Brain Chemistry; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Motor Activity; Naphthalenes; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1986
The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism. Psychopharmacology, 1986, Volume: 90, Issue:4 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Carbidopa; Drug Synergism; Fenclonine; Indoles; Lithium; Male; Methoxydimethyltryptamines; Motor Activity; Naphthalenes; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1986
The 5-hydroxytryptamine (5-HT2) receptor stimulates inositol phosphate formation in intact and broken WRK1 cells: determination of occupancy-response relationships for 5-HT agonists. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bufotenin; Cell Line; Dibenzylchlorethamine; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Indoles; Inositol Phosphates; Kinetics; Mammary Neoplasms, Experimental; Mathematics; N,N-Dimethyltryptamine; Piperazines; Quipazine; Rats; Receptors, Serotonin; Sugar Phosphates; Tetrahydronaphthalenes; Tryptamines	1987
The role of putative 5-HT1A and 5-HT1B receptors in the control of feeding in rats. Life sciences, 1987, Aug-03, Volume: 41, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite; Feeding Behavior; Food Deprivation; Indoles; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1987
5-HT2 receptors could be primarily involved in the regulation of slow-wave sleep in the rat. European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Indoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Sleep; Tetrahydronaphthalenes	1987
The effects of 8-hydroxy-2-(di-n-propylamino)tetralin and other serotonergic agonists on performance in a radial maze: a possible role for 5-HT1A receptors in memory. Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Indoles; Lysergic Acid Diethylamide; Male; Memory; Methoxydimethyltryptamines; Naphthalenes; Piperazines; Rats; Rats, Inbred F344; Receptors, Serotonin; Tetrahydronaphthalenes	1987
Identification of 5-hydroxytryptamine binding site subtypes in rat spinal cord. Brain research, 1987, Dec-08, Volume: 436, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Ergolines; In Vitro Techniques; Indoles; Rats; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes	1987
Lack of variation over 24-hours in response to stimulation of 5-HT1 receptors in the mouse brain. Chronobiology international, 1985, Volume: 2, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Circadian Rhythm; Hypothermia; Indoles; Male; Mice; Motor Activity; Naphthalenes; Receptors, Serotonin; Tetrahydronaphthalenes	1985
Differential patterns of local cerebral glucose utilization in response to 5-hydroxytryptamine agonists. Neuroscience, 1988, Volume: 25, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Deoxy Sugars; Deoxyglucose; Indoles; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
Heterogeneous effects of serotonin in the dorsal horn of rat: the involvement of 5-HT1 receptor subtypes. Brain research, 1988, Jul-19, Volume: 456, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Indoles; Ketanserin; Male; Neurons, Afferent; Pain; Physical Stimulation; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes	1988
The effects of acute and repeated administration of T3 to mice on 5-HT1 and 5-HT2 function in the brain and its influence on the actions of repeated electroconvulsive shock. Neuropharmacology, 1988, Volume: 27, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Electroshock; Hypothermia; Indoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Triiodothyronine	1988
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons. European journal of pharmacology, 1986, Jan-21, Volume: 120, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; Fetus; Indoles; Ketanserin; Metergoline; Mice; Neurons; Piperidines; Pregnancy; Receptors, Serotonin; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide	1986
Lithium decreases 5-HT1A and 5-HT2 receptor and alpha 2-adrenoceptor mediated function in mice. Psychopharmacology, 1986, Volume: 90, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Clonidine; Indoles; Lithium; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Adrenergic, alpha; Receptors, Serotonin; Tetrahydronaphthalenes	1986
Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity. European journal of pharmacology, 1985, Jun-19, Volume: 112, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Binding Sites; Blood Pressure; In Vitro Techniques; Indoles; Male; Naphthalenes; Pentobarbital; Pindolol; Rats; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes	1985
Evidence that 5-HT agonist-induced rotational behaviour in the rat is mediated via 5-HT1 receptors. Psychopharmacology, 1984, Volume: 83, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Indoles; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rotation; Serotonin Antagonists; Tetrahydronaphthalenes	1984
Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes. Journal of receptor research, 1984, Volume: 4, Issue:1-6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Autoradiography; Benzodiazepinones; Binding, Competitive; Brain; Carbachol; Hippocampus; Indoles; Oxotremorine; Pindolol; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Serotonin; Superior Colliculi; Tetrahydronaphthalenes	1984
Chronic treatment with fluvoxamine by osmotic minipumps fails to induce persistent functional changes in central 5-HT1A and 5-HT1B receptors, as measured by in vivo microdialysis in dorsal hippocampus of conscious rats. Psychopharmacology, 1995, Volume: 117, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Drug Delivery Systems; Fluvoxamine; Hippocampus; Indoles; Injections, Subcutaneous; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists	1995
Distractibility and locomotor activity in rat following intra-collicular injection of a serotonin 1B-1D agonist. Behavioural brain research, 1995, Volume: 67, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Attention; Axons; Brain Mapping; Dipeptides; Indoles; Male; Microinjections; Motor Activity; Rats; Receptors, Serotonin; Retinal Ganglion Cells; Serotonin; Serotonin Receptor Agonists; Superior Colliculi; Synaptic Transmission; Visual Pathways	1995
Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Biguanides; Circadian Rhythm; Darkness; Energy Metabolism; Feeding Behavior; Indoles; Light; Male; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Time Factors	1995
Effects of 21 days treatment with fluoxetine on stimulated endogenous 5-hydroxytryptamine overflow in the rat dorsal raphe and suprachiasmatic nucleus studied using fast cyclic voltammetry in vitro. Brain research, 1994, Mar-21, Volume: 640, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Electric Stimulation; Electrophysiology; Fluoxetine; In Vitro Techniques; Indoles; Male; Methiothepin; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus	1994
Activity of serotonin (5-HT) receptor agonists, partial agonists and antagonists at cloned human 5-HT1A receptors that are negatively coupled to adenylate cyclase in permanently transfected HeLa cells. Biochemical pharmacology, 1993, Jan-26, Volume: 45, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Colforsin; Cyclic AMP; HeLa Cells; Humans; Indoles; Lysergic Acid Diethylamide; Models, Biological; Pindolol; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Transfection	1993
Effect of 5-HT-1A receptor agonists on paw licking reaction on hot plate and unpunished drinking in rat. Life sciences, 1993, Volume: 52, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Drinking Behavior; Indoles; Male; Pain; Prosencephalon; Punishment; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Thirst; Time Factors	1993
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines	1996
The role of 5-HT1A and 5-HT1B receptors in antidepressant drug actions in the mouse forced swimming test. European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Immobilization; Indoles; Male; Mice; Pindolol; Receptors, Serotonin; Swimming	1996
The effects of a 5-HT1A receptor agonist and antagonist on the 5-hydroxytryptamine release in the central nucleus of the amygdala: a microdialysis study with flesinoxan and WAY 100635. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Indoles; Male; Microdialysis; Piperazines; Potassium Chloride; Pyridines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin	1997
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Discrimination Learning; Fluvoxamine; Indoles; Pindolol; Piperazines; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles	1997
Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology, 1997, Volume: 132, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Indoles; Male; Mice; Mice, Knockout; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reflex, Startle; Serotonin Receptor Agonists	1997
RU24969-induced behavioural syndrome requires activation of both 5HT1A and 5HT1B receptors. Psychopharmacology, 1997, Volume: 132, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Indoles; Male; Motor Activity; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior	1997
Serotonin-1B agonists induce compartmentally organized striatal Fos expression in rats. Neuroreport, 1998, Apr-20, Volume: 9, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Corpus Striatum; Immunohistochemistry; Indoles; Male; Nerve Tissue Proteins; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists	1998
Serotonin1B receptor stimulation enhances cocaine reinforcement. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists	1998
The pharmacology of impulsive behaviour in rats IV: the effects of selective serotonergic agents on a paced fixed consecutive number schedule. Psychopharmacology, 1998, Volume: 140, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Impulsive Behavior; Indoles; Male; Metergoline; p-Chloroamphetamine; Rats; Reinforcement, Psychology; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes	1998
Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Antidepressive Agents; Apomorphine; Brain; Clonidine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Indoles; Male; Mice; Motor Activity; Norepinephrine; Paroxetine; Pindolol; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	1998
Activation of 5-HT1B receptors in the nucleus accumbens reduces amphetamine-induced enhancement of responding for conditioned reward. Psychopharmacology, 1999, Volume: 142, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Conditioning, Psychological; Indoles; Male; Nucleus Accumbens; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reward; Serotonin; Serotonin Receptor Agonists; Water	1999
Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Female; Habituation, Psychophysiologic; Indoles; Mice; Mice, Knockout; Neural Inhibition; Piperazines; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Serotonin Receptor Agonists	2000
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Indoles; Mice; Mice, Inbred Strains; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	2001
Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices. Journal of neurochemistry, 2001, Volume: 79, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Male; Oxadiazoles; Pindolol; Piperazines; Potassium; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Ventral Tegmental Area	2001
Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats. Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Exploratory Behavior; Indoles; Male; Microinjections; Motor Activity; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Substantia Nigra; Subthalamus	2002
Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biological psychiatry, 2009, Mar-01, Volume: 65, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Globus Pallidus; Indoles; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra	2009
Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation. PloS one, 2009, Nov-11, Volume: 4, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Chlordiazepoxide; Female; Indoles; Light; Male; Maze Learning; Mice; Mice, Inbred C57BL; Phosphorylation	2009
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice. Biological psychiatry, 2011, Dec-01, Volume: 70, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clomipramine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Female; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Iodocyanopindolol; Isotopes; Mice; Mice, Inbred BALB C; Neural Inhibition; Obsessive-Compulsive Disorder; Prefrontal Cortex; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Swimming; Time Factors	2011
MDMA self-administration fails to alter the behavioral response to 5-HT(1A) and 5-HT(1B) agonists. Psychopharmacology, 2016, Volume: 233, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Indoles; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists	2016