5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole has been researched along with 1-(3-chlorophenyl)piperazine in 22 studies
| Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole) | Studies (1-(3-chlorophenyl)piperazine) | Trials (1-(3-chlorophenyl)piperazine) | Recent Studies (post-2010) (1-(3-chlorophenyl)piperazine) |
|---|---|---|---|---|---|
| 218 | 0 | 12 | 833 | 142 | 87 |
| Protein | Taxonomy | 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50) | 1-(3-chlorophenyl)piperazine (IC50) |
|---|---|---|---|
| Beta-1 adrenergic receptor | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 14 (63.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Glennon, RA | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Barrett, JE; Gleeson, S; Seggel, MR; Weissman, BA | 1 |
| Eide, PK | 1 |
| Curzon, G | 1 |
| Broekkamp, CL; Jenck, F; Van Delft, AM | 1 |
| Simansky, KJ; Vaidya, AH | 1 |
| Eide, PK; Hole, K; Joly, NM | 1 |
| Frances, H; Khidichian, F | 1 |
| Cooper, SJ; Neill, JC | 1 |
| Agmo, A; Escalante, A; Fernández-Guasti, A | 1 |
| Curzon, G; Kennett, GA | 2 |
| Curzon, G; Dourish, CT; Kennett, GA | 1 |
| Reid, A; Sawynok, J | 1 |
| Dourish, CT; Kitchener, SJ | 1 |
| Rabin, RA; Winter, JC | 1 |
| Herremans, AH; Mos, J; Olivier, B; Van Drimmelen, M; Van Hest, A | 1 |
| Clifton, PG; Dourish, CT; Hewitt, KN; Lee, MD | 1 |
2 review(s) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Effects of tryptophan and of 5-hydroxytryptamine receptor subtype agonists on feeding.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite; Brain; Dietary Carbohydrates; Feeding Behavior; Female; Food Deprivation; Food Preferences; Humans; Indoles; Male; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sex Factors; Tetrahydronaphthalenes; Tryptophan | 1991 |
20 other study(ies) available for 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Neurochemical effects of 5-HT1 receptor ligands in pigeons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Columbidae; Hydroxyindoleacetic Acid; Indoles; Male; Methoxyhydroxyphenylglycol; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1992 |
Stimulation of 5-HT1 receptors in the spinal cord changes substance P-induced behaviour.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesia; Animals; Indoles; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurons; Pain; Piperazines; Quipazine; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotyped Behavior; Substance P | 1992 |
5-HT1C receptors in the serotonergic control of periaqueductal gray induced aversion in rats.
Topics: Amphetamines; Animals; Cyproheptadine; Indoles; Ketanserin; Male; Periaqueductal Gray; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reinforcement, Psychology; Ritanserin; Serotonin; Serotonin Antagonists | 1990 |
Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonists.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Appetite; Eating; Feeding Behavior; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Satiation; Sertraline; Tetrahydronaphthalenes | 1990 |
The role of spinal cord 5-HT1A and 5-HT1B receptors in the modulation of a spinal nociceptive reflex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Indoles; Injections, Spinal; Male; Methoxydimethyltryptamines; Mice; Pain; Pain Measurement; Piperazines; Reaction Time; Receptors, Serotonin; Reflex; Serotonin Antagonists; Skin Temperature; Spinal Cord; Tetrahydronaphthalenes | 1990 |
Chronic but not acute antidepressants interfere with serotonin (5-HT1B) receptors.
Topics: Animals; Antidepressive Agents; Escape Reaction; Fluoxetine; Indoles; Injections, Intraperitoneal; Male; Mice; Phenelzine; Piperazines; Receptors, Serotonin; Time Factors | 1990 |
Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1C receptor mediation.
Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Fenfluramine; Fluoxetine; Hypertonic Solutions; Indoles; Male; Piperazines; Pyrazines; Quinoxalines; Quipazine; Rats; Receptors, Serotonin; Serotonin | 1989 |
Inhibitory action of various 5-HT1B receptor agonists on rat masculine sexual behaviour.
Topics: Animals; Indoles; Male; Piperazines; Psychomotor Performance; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sexual Behavior, Animal | 1989 |
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1988 |
The antiemetic drug trimethobenzamide prevents hypophagia due to acetyl salicylate, but not to 5-HT1B or 5-HT1C agonists.
Topics: Animals; Antiemetics; Aspirin; Benzamides; Feeding Behavior; Food Deprivation; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Serotonin | 1988 |
5-HT1B agonists induce anorexia at a postsynaptic site.
Topics: Animals; Appetite Depressants; Haloperidol; Indoles; Ketanserin; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synapses | 1987 |
Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Analgesia; Analgesics; Analysis of Variance; Animals; Binding Sites; Indoles; Injections, Spinal; Male; Pain; Piperazines; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Up-Regulation | 1994 |
An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats.
Topics: Amphetamines; Animals; Eating; Feeding Behavior; Grooming; Indoles; Male; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Satiety Response; Serotonin Receptor Agonists | 1994 |
Discriminative stimulus properties of m-chlorophenylpiperazine.
Topics: Animals; Discrimination Learning; Generalization, Stimulus; Indoles; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Discrimination Learning; Fluvoxamine; Indoles; Pindolol; Piperazines; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 1997 |
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.
Topics: Aminopyridines; Animals; Diet; Dose-Response Relationship, Drug; Ethylamines; Feeding Behavior; Indoles; Mice; Oxadiazoles; Piperazines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Satiety Response; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |