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5-iodotubercidin and adenosine kinase

5-iodotubercidin has been researched along with adenosine kinase in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (12.50)	18.7374
1990's	29 (51.79)	18.2507
2000's	13 (23.21)	29.6817
2010's	6 (10.71)	24.3611
2020's	1 (1.79)	2.80

Authors

Authors	Studies
Berne, RM; Coleman, SD; Ely, SW; Matherne, GP	1
Duley, JA; Montero, C; Simmonds, HA; Smolenski, RT	1
de Jong, JW; Den Boer, PJ; Grootegoed, JA; Mackenbach, P	1
Barankiewicz, J; Gruber, HE; Jimenez, R; Ronlov, G	1
Meghji, P; Middleton, KM; Newby, AC	1
Fox, IH; Hurley, MC; Lin, B	1
Baird-Lambert, J; Davies, LP; Marwood, JF	1
Basuyau, JP; Chedeville, A; Claeyssens, S; Hamet, M; Lavoinne, A	1
Berens, RL; LaFon, SW; Marr, JJ; Nelson, DJ	1
Holmquist, CA; Newby, AC	1
Holmquist, CA; Illingworth, J; Newby, AC; Pearson, JD	1
Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Node, K; Takeda, H	1
Corsi, C; Fratti, S; Pazzagli, M; Pedata, F; Pepeu, G	1
Fredholm, BB; Lloyd, HG	1
el Kouni, MH; Iltzsch, MH; Tankersley, KO; Uber, SS	1
Decking, UK; Haas, HL; Pak, MA; Schrader, J	1
Bollen, M; Massillon, D; Stalmans, W; van de Werve, G	1
Carson, DA; Cottam, HB; Di Pasquale, G; Raychaudhuri, A; Shih, HC; Wasson, DB	1
Phillis, JW; Smith-Barbour, M	1
Bontemps, F; Van den Berghe, G; Vincent, MF	1
Sciotti, VM; Van Wylen, DG	1
Bading, B; Deussen, A; Kelm, M; Schrader, J	1
Flückiger-Isler, RE; Walter, P	1
Geiger, JD; Parkinson, FE	1
Hrnjez, BJ; Matthews, JB; Mun, EC; Smith, JA; Tally, KJ	1
Gupta, RS	1
Golembiowska, K; Sawynok, J; White, TD	1
Cook, AF; Davies, LP	1
Kroll, K; Stepp, DW	1
Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z	1
Kalsi, KK; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M	1
Manthei, SA; Reiling, CM; Van Wylen, DG	1
Hebb, MO; White, TD	1
Gordon, PB; Grotterød, EM; Kovács, AL; Seglen, PO	1
Deussen, A; Kelm, M; Schäfer, S; Stappert, M	1
Barankiewicz, J; Castellino, AJ; Dumas, DP; Erion, MD; Foster, AC; Gruber, HE; Ugarkar, BG; Wiesner, JB	1
Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H	1
Brennan, RG; Ealick, SE; Mathews, II; Roos, DS; Schumacher, MA; Scott, DM; Ullman, B	1
Abbracchio, MP; Camurri, A; Ceruti, S; Falzano, L; Fiorentini, C; Frank, C; Giammarioli, AM; Malorni, W; Rufini, S	1
Gołembiowska, K; Zylewska, A	1
Baldwin, SA; Cass, CE; LaRivière, CG; Parkinson, FE; Powell, AE; Sinclair, CJ; Xiong, W; Young, JD	1
Gray, CC; Kalsi, KK; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M	1
Cioroch, M; Makarewicz, W; Skladanowski, AC; Tkacz, K	1
Boison, D; Fritschy, JM; Gouder, N; Scheurer, L	1
Benton, HP; MacDonald, MH; Petrov, R; Tesch, AM	1
Boison, D; Crestani, F; Fedele, DE; Gabernet, L; Gouder, N; Güttinger, M; Rülicke, T; Scheurer, L	1
Boison, D; Pignataro, G; Simon, RP	1
Carneiro, FS; Carneiro, ZN; Giachini, FRC; Inscho, EW; Leite, R; Lima, VV; Tostes, RC; Webb, RC	1
Boison, D; Dale, N; Etherington, LA; Frenguelli, BG; Irving, AJ; Meechan, L; Patterson, GE	1
Boison, D; Li, T; Shen, HY	1
Fukuda, M; Hino, H; Ishii, E; Kuzume, K; Morimoto, T; Suzuki, Y	1
Bhutoria, S; Ghoshal, N	1
Boison, D; Granja, TF; Köhler, D; Morote-García, JC; Rosenberger, P; Schneider, M; Straub, A; Streienberger, A	1
Acharya, MM; Allen, BD; Baddour, AA; Baulch, JE; Giedzinski, E; Kawashita, T; Nguyen, TH; Parihar, VK; Syage, AR; Yoon, N; Yu, L	1
Bigej, R; Boison, D; Friedman, JL; Saleumvong, B; Sandau, US; Yahya, M	1
Ashraf, O; Boison, D; Chitravanshi, V; Fedele, DE; Huynh, T; Murugan, M; Purnell, BS	1

Other Studies

56 other study(ies) available for 5-iodotubercidin and adenosine kinase

Article	Year
Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentrations and coronary flow. Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:11 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Coronary Circulation; Extracellular Space; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Tubercidin; Vascular Resistance	1992
Effects of adenosine analogues on ATP concentrations in human erythrocytes. Further evidence for a route independent of adenosine kinase. Biochemical pharmacology, 1991, Oct-09, Volume: 42, Issue:9 Topics: Adenine Phosphoribosyltransferase; Adenosine Kinase; Adenosine Triphosphate; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Pentostatin; Tubercidin	1991
Effects of glucose and adenosine on the ATP content of hamster spermatids. Reproduction, fertility, and development, 1990, Volume: 2, Issue:2 Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Fructose; Galactose; Glucose; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Mannose; Spermatids; Tubercidin	1990
Selective adenosine release from human B but not T lymphoid cell line. The Journal of biological chemistry, 1990, Sep-15, Volume: 265, Issue:26 Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Line; Deoxyglucose; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Models, Biological; Pentostatin; Rats; T-Lymphocytes; Tubercidin	1990
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts. The Biochemical journal, 1988, Feb-01, Volume: 249, Issue:3 Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adult; AMP Deaminase; Animals; Columbidae; Coronary Disease; Female; Heart; Histocytochemistry; Humans; Male; Middle Aged; Myocardium; Nucleotidases; Nucleotides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Species Specificity; Tubercidin	1988
Regulation of deoxyadenosine and nucleoside analog phosphorylation by human placental adenosine kinase. The Journal of biological chemistry, 1985, Dec-15, Volume: 260, Issue:29 Topics: Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Deoxyadenosines; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Methylthioinosine; Nucleosides; Nucleotides; Phosphorylation; Phosphotransferases; Placenta; Potassium Chloride; Pregnancy; Tubercidin; Vidarabine	1985
Studies on several pyrrolo[2,3-d]pyrimidine analogues of adenosine which lack significant agonist activity at A1 and A2 receptors but have potent pharmacological activity in vivo. Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18 Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Brain; Cyclic AMP; Guanosine; Guinea Pigs; Heart Rate; Male; Mice; Muscle Relaxation; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tubercidin	1986
Influence of 2-chloroadenosine on the nucleotide content of isolated rat hepatocytes. FEBS letters, 1988, May-23, Volume: 232, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Kinetics; Liver; Male; Nucleotides; Phosphorylation; Piperazines; Rats; Rats, Inbred Strains; Spectrophotometry; Tubercidin	1988
Inosine analogs. Their metabolism in mouse L cells and in Leishmania donovani. The Journal of biological chemistry, 1985, Aug-15, Volume: 260, Issue:17 Topics: Adenosine Kinase; Adenosine Triphosphate; Animals; Cell Line; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Fibroblasts; Guanosine Triphosphate; Inosine; Inosine Triphosphate; Leishmania; Mice; Tubercidin	1985
Adenosine production inside rat polymorphonuclear leucocytes. The Biochemical journal, 1981, Nov-15, Volume: 200, Issue:2 Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Coformycin; Neutrophils; Nucleotidases; Pentostatin; Rats; Tubercidin	1981
The control of adenosine concentration in polymorphonuclear leucocytes, cultured heart cells and isolated perfused heart from the rat. The Biochemical journal, 1983, Aug-15, Volume: 214, Issue:2 Topics: Adenosine; Adenosine Kinase; Animals; Cells, Cultured; Coformycin; Heart; In Vitro Techniques; Male; Myocardium; Neutrophils; Pentostatin; Perfusion; Rats; Rats, Inbred Strains; Tubercidin	1983
Activation of protein kinase C increases adenosine production in the hypoxic canine coronary artery through the extracellular pathway. Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:12 Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Arteries; Coronary Vessels; Dogs; Enzyme Activation; Hypoxia; In Vitro Techniques; Pentostatin; Protein Kinase C; Tubercidin	1995
Regulation of extracellular adenosine levels in the striatum of aging rats. Brain research, 1995, Jun-26, Volume: 684, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin	1995
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices. Neurochemistry international, 1995, Volume: 26, Issue:4 Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Basal Metabolism; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Purines; Rats; Tubercidin	1995
Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii. Biochemical pharmacology, 1995, May-17, Volume: 49, Issue:10 Topics: Adenosine; Adenosine Kinase; Animals; Antiprotozoal Agents; Drug Design; Ligands; Purine Nucleosides; Structure-Activity Relationship; Toxoplasma; Tubercidin	1995
Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices. Neuropharmacology, 1994, Volume: 33, Issue:9 Topics: Adenosine; Adenosine Kinase; Animals; Hippocampus; In Vitro Techniques; Inosine; Kinetics; Membrane Potentials; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Tubercidin; Xanthines	1994
Identification of the glycogenic compound 5-iodotubercidin as a general protein kinase inhibitor. The Biochemical journal, 1994, Apr-01, Volume: 299 ( Pt 1) Topics: Adenosine Kinase; Animals; Glucagon; Glycogen Synthase; Liver; Male; Peptides; Phosphorylase Kinase; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Tubercidin; Vasopressins	1994
New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Adenosine Kinase; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Drug Evaluation, Preclinical; Humans; Kinetics; Lymphocytes; Pleurisy; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Tubercidin	1993
The adenosine kinase inhibitor, 5-iodotubercidin, is not protective against cerebral ischemic injury in the gerbil. Life sciences, 1993, Volume: 53, Issue:6 Topics: Adenosine Kinase; Animals; Body Temperature; Brain Ischemia; Gerbillinae; Hippocampus; Male; Motor Activity; Tubercidin	1993
Mechanisms of elevation of adenosine levels in anoxic hepatocytes. The Biochemical journal, 1993, Mar-15, Volume: 290 ( Pt 3) Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Amobarbital; Animals; Carbon Dioxide; Cell Membrane; Liver; Male; Nitrogen; Oxygen; Pentostatin; Phosphoric Monoester Hydrolases; Potassium Cyanide; Rats; Rats, Wistar; Tubercidin	1993
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin	1993
Formation and salvage of adenosine by macrovascular endothelial cells. The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2 Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Firefly Luciferin; Kinetics; Luciferases; Microspheres; Phosphorylation; Swine; Tubercidin	1993
Stimulation of rat liver glycogen synthesis by the adenosine kinase inhibitor 5-iodotubercidin. The Biochemical journal, 1993, May-15, Volume: 292 ( Pt 1) Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Amino Acids; Animals; Cells, Cultured; Liver; Liver Glycogen; Male; Rats; Rats, Wistar; Tubercidin	1993
Effects of iodotubercidin on adenosine kinase activity and nucleoside transport in DDT1 MF-2 smooth muscle cells. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3 Topics: Adenosine Kinase; Animals; Cricetinae; Dose-Response Relationship, Drug; Kinetics; Muscle, Smooth; Nucleosides; Radioligand Assay; Tubercidin	1996
Adenosine scavenging: a novel mechanism of chloride secretory control in intestinal epithelial cells. Surgery, 1996, Volume: 120, Issue:2 Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Biological Transport; Buffers; Cells, Cultured; Chlorides; Chromatography, High Pressure Liquid; Cyclic AMP; Dipyridamole; Enzyme Inhibitors; Humans; Intestinal Mucosa; Membrane Proteins; Nucleosides; Phosphodiesterase Inhibitors; Phosphorylation; Tubercidin; Vasodilator Agents	1996
Adenosine-AMP exchange activity is an integral part of the mammalian adenosine kinase. Biochemistry and molecular biology international, 1996, Volume: 39, Issue:3 Topics: Adenosine; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arsenates; Cattle; CHO Cells; Cricetinae; Enzyme Inhibitors; Enzyme Stability; Kinetics; Liver; Magnesium; Mutation; Phosphates; Temperature; Toyocamycin; Tubercidin	1996
Adenosine kinase inhibitors augment release of adenosine from spinal cord slices. European journal of pharmacology, 1996, Jun-27, Volume: 307, Issue:2 Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Spinal Cord; Tubercidin	1996
Inhibition of adenosine kinase and adenosine uptake in guinea-pig CNS tissue by halogenated tubercidin analogues. Life sciences, 1995, Mar-17, Volume: 56, Issue:17 Topics: Adenosine; Adenosine Kinase; Animals; Cerebral Cortex; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Tubercidin	1995
Adenosine kinetics in canine coronary circulation. The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2 Topics: Adenosine; Adenosine Kinase; Animals; Biological Transport; Capillaries; Computer Simulation; Coronary Circulation; Dipyridamole; Dogs; Endothelium, Vascular; Female; Hemodynamics; In Vitro Techniques; Indicator Dilution Techniques; Kinetics; Male; Models, Cardiovascular; Nitroglycerin; Tubercidin; Veins	1996
Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors. Circulation, 1997, Oct-21, Volume: 96, Issue:8 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cattle; Cell Division; Culture Media; Dipyridamole; DNA Replication; Enzyme Inhibitors; Fibroblasts; Heart; Male; Myocardium; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tubercidin; Xanthines	1997
Adenine/ribose supply increases adenosine production and protects ATP pool in adenosine kinase-inhibited cardiac cells. Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:3 Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Male; Myocardium; Purines; Rats; Rats, Sprague-Dawley; Ribose; Tubercidin; Uridine	1998
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition. Cardiovascular research, 1998, Volume: 37, Issue:1 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin	1998
Co-administration of adenosine kinase and deaminase inhibitors produces supra-additive potentiation of N-methyl-D-aspartate-evoked adenosine formation in cortex. European journal of pharmacology, 1998, Mar-05, Volume: 344, Issue:2-3 Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cerebral Cortex; Deoxyadenosines; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tubercidin	1998
Inhibition of hepatocytic autophagy by adenosine, adenosine analogs and AMP. Biological chemistry, 1998, Volume: 379, Issue:11 Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Monophosphate; Animals; Autophagy; Cells, Cultured; Enzyme Inhibitors; Liver; Male; Pentostatin; Phosphorylation; Rats; Rats, Wistar; Tubercidin	1998
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient. Circulation, 1999, Apr-20, Volume: 99, Issue:15 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin	1999
Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Cattle; Cells, Cultured; Deoxyadenosines; Electroshock; Endothelium, Vascular; Enzyme Inhibitors; Male; Microcirculation; Motor Activity; Neocortex; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred Strains; Recombinant Proteins; Seizures; Structure-Activity Relationship; Tubercidin	1999
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines	2000
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. Journal of molecular biology, 2000, May-19, Volume: 298, Issue:5 Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Amino Acid Sequence; Animals; Anions; Antiprotozoal Agents; Apoenzymes; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Humans; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Prodrugs; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity; Toxoplasma; Tubercidin; Water	2000
Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms. Neuromuscular disorders : NMD, 2000, Volume: 10, Issue:6 Topics: 2-Chloroadenosine; Acetylcysteine; Actin Cytoskeleton; Adenosine; Adenosine Kinase; Animals; Apoptosis; Cell Adhesion; Cell Line; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Homocysteine; Intracellular Fluid; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Thioinosine; Tubercidin	2000
Effect of adenosine kinase, adenosine deaminase and transport inhibitors on striatal dopamine and stereotypy after methamphetamine administration. Neuropharmacology, 2000, Aug-23, Volume: 39, Issue:11 Topics: Adenosine Deaminase; Adenosine Kinase; Animals; Corpus Striatum; Dilazep; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Male; Methamphetamine; Pentostatin; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Tubercidin	2000
Nucleoside transporter subtype expression: effects on potency of adenosine kinase inhibitors. British journal of pharmacology, 2001, Volume: 134, Issue:5 Topics: Adenine Nucleotides; Adenosine; Adenosine Kinase; Animals; Carrier Proteins; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Tumor Cells, Cultured	2001
The effect of adenosine metabolism inhibition and nucleotide precursor supply on adenosine production in human heart endothelial cells. Advances in experimental medicine and biology, 2000, Volume: 486 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nucleotides; Pentostatin; Phosphates; Ribose; Tubercidin	2000
The cytotoxic effect of purine riboside on COS-7 cells. Advances in experimental medicine and biology, 2000, Volume: 486 Topics: 5'-Nucleotidase; Adenosine Kinase; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cell Survival; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Humans; Kinetics; Purine Nucleosides; Ribonucleosides; Tubercidin	2000
Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-21, Volume: 24, Issue:3 Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Neurons; Tubercidin; Xanthines	2004
Inhibition of adenosine kinase attenuates interleukin-1- and lipopolysaccharide-induced alterations in articular cartilage metabolism. Osteoarthritis and cartilage, 2005, Volume: 13, Issue:3 Topics: Adenosine; Adenosine Kinase; Animals; Cartilage, Articular; Culture Media, Conditioned; Dinoprostone; Enzyme Inhibitors; Glycosaminoglycans; Horses; Interleukin-1; Lipopolysaccharides; Matrix Metalloproteinase 3; Nitric Oxide; Tissue Culture Techniques; Tubercidin	2005
Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation. Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 10 Topics: Adenosine Kinase; Animals; Astrocytes; Behavior, Animal; Brain; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Gliosis; Hippocampus; Kainic Acid; Locomotion; Male; Mice; Mice, Transgenic; Neurons; Transgenes; Tubercidin; Up-Regulation	2005
Transgenic overexpression of adenosine kinase aggravates cell death in ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:1 Topics: Adenosine; Adenosine Kinase; Animals; Brain Ischemia; Cell Death; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Promoter Regions, Genetic; Pyramidal Cells; Receptor, Adenosine A1; Tubercidin; Ubiquitin	2007
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse. The journal of sexual medicine, 2008, Volume: 5, Issue:5 Topics: Acetylcholine; Adenosine; Adenosine Kinase; Animals; Diabetes Mellitus, Type 2; Dipyridamole; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Male; Mice; Mice, Mutant Strains; Mice, Obese; Muscle Contraction; Muscle, Smooth; Nitroprusside; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Tubercidin; Vasoconstrictor Agents; Vasodilator Agents	2008
Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus. Neuropharmacology, 2009, Volume: 56, Issue:2 Topics: Adenosine; Adenosine Kinase; Animals; Animals, Newborn; Astrocytes; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Theophylline; Time Factors; Tubercidin	2009
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance. Epilepsia, 2010, Volume: 51, Issue:3 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin	2010
Adenosine A1 receptor blockage mediates theophylline-associated seizures. Epilepsia, 2010, Volume: 51, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew; Seizures; Theophylline; Tubercidin	2010
Deciphering ligand dependent degree of binding site closure and its implication in inhibitor design: A modeling study on human adenosine kinase. Journal of molecular graphics & modelling, 2010, Feb-26, Volume: 28, Issue:6 Topics: Adenosine Kinase; Binding Sites; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Ligands; Models, Molecular; Protein Conformation; Structural Homology, Protein; Structure-Activity Relationship; Tubercidin; User-Computer Interface	2010
Inhibition of Adenosine Kinase Attenuates Acute Lung Injury. Critical care medicine, 2016, Volume: 44, Issue:4 Topics: Acute Lung Injury; Adenosine Kinase; Animals; B-Lymphocytes; Bronchoalveolar Lavage Fluid; Cell Line; Cytokines; Lipopolysaccharides; Lung; Mice; Pneumonia; Prospective Studies; Tubercidin	2016
Epigenetic determinants of space radiation-induced cognitive dysfunction. Scientific reports, 2017, 02-21, Volume: 7 Topics: 5-Methylcytosine; Adenosine Kinase; Animals; Behavior, Animal; Brain; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Epigenomics; Hippocampus; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins; Tubercidin; Whole-Body Irradiation	2017
Transient use of a systemic adenosine kinase inhibitor attenuates epilepsy development in mice. Epilepsia, 2019, Volume: 60, Issue:4 Topics: Adenosine Kinase; Animals; Anticonvulsants; Brain; Enzyme Inhibitors; Epilepsy; Male; Mice; Mice, Inbred C57BL; Tubercidin	2019
Suppression of phrenic nerve activity as a potential predictor of imminent sudden unexpected death in epilepsy (SUDEP). Neuropharmacology, 2021, 02-15, Volume: 184 Topics: Adenosine Kinase; Animals; Kainic Acid; Male; Phrenic Nerve; Predictive Value of Tests; Rats; Rats, Wistar; Seizures; Sudden Unexpected Death in Epilepsy; Tubercidin	2021