Page last updated: 2024-09-03

5-iodobenzovesamicol and piperidines

5-iodobenzovesamicol has been researched along with piperidines in 16 studies

Compound Research Comparison

Studies
(5-iodobenzovesamicol)
Trials
(5-iodobenzovesamicol)
Recent Studies (post-2010)
(5-iodobenzovesamicol)
Studies
(piperidines)
Trials
(piperidines)
Recent Studies (post-2010) (piperidines)
172340,2355,22114,545

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (31.25)18.2507
2000's8 (50.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gildersleeve, DL; Jung, YW; Van Dort, ME; Wieland, DM1
Gildersleeve, DL; Jung, YW; Wieland, DM1
Ackermann, RJ; Carey, JE; Fessler, JA; Frey, KA; Gildersleeve, DL; Koeppe, RA; Kuhl, DE; Minoshima, S; Wieland, DM1
Gildersleeve, DL; Hagen, CA; Jung, YW; Kuhl, DE; Van Dort, ME; Wieland, DM1
del Rosario, R; Frey, KA; Gildersleeve, DL; Jung, YW; Kuhl, DE; Mulholland, GK; Raffel, DM; Sherman, PS; Van Dort, ME; Wieland, DM1
Dannenberg, C; Georgi, P; Heinicke, J; Kämpfer, I; Rossner, S; Schliebs, R; Sorger, D1
Kuhl, DE; Minoshima, S; Smith, YR; Zubieta, JK1
Albin, RL; Cornblath, WT; Cross, D; Frey, KA; Minoshima, S; Wald, JA; Wernette, K1
An, H; Chervin, RD; Consens, FB; Gilman, S; Heumann, M; Junck, L; Koeppe, RA; Little, R2
Chalon, S; Guilloteau, D; Henderson, J; Kassiou, M; Katsifis, A; Quinlivan, M; Vergote, J1
Bodard, S; Chalon, S; Eberl, S; Emond, P; Fulham, MJ; Fulton, RR; Garreau, L; Giboureau, N; Guilloteau, D; Henderson, DJ; Kassiou, M; Mavel, S; Roselt, P1
Allard, M; Barret, O; Mazère, J; Seibyl, J1
Bibat, G; Brašić, JR; Dogan, AS; Guevara, MR; Hilton, J; Johnston, M; Kumar, A; Naidu, S; Stephane, M; Wong, DF; Yablonski, ME; Zhou, Y1
Allard, M; Guilloteau, D; Lamare, F; Mayo, W; Mazère, J; Meissner, WG; Sibon, I; Tison, F1
Allard, M; Fernandez, P; Lamare, F; Mayo, W; Mazère, J1

Trials

2 trial(s) available for 5-iodobenzovesamicol and piperidines

ArticleYear
REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA.
    Neurology, 2003, Jul-08, Volume: 61, Issue:1

    Topics: Adult; Age Distribution; Aged; Binding, Competitive; Biogenic Monoamines; Carbon Radioisotopes; Corpus Striatum; Electromyography; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Multiple System Atrophy; Piperidines; Polysomnography; Predictive Value of Tests; Reference Values; REM Sleep Behavior Disorder; Sex Distribution; Tetrabenazine; Tetrahydronaphthalenes; Thalamus; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

2003
Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA.
    Neurology, 2003, Jul-08, Volume: 61, Issue:1

    Topics: Adult; Age Distribution; Aged; Binding, Competitive; Carrier Proteins; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Multiple System Atrophy; Neuropeptides; Pilot Projects; Piperidines; Pons; Receptors, Cholinergic; Reference Values; Regression Analysis; Sex Distribution; Sleep Apnea, Obstructive; Tetrabenazine; Tetrahydronaphthalenes; Thalamus; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins; Vesicular Biogenic Amine Transport Proteins; Vesicular Transport Proteins

2003

Other Studies

14 other study(ies) available for 5-iodobenzovesamicol and piperidines

ArticleYear
A radiotracer for mapping cholinergic neurons of the brain.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Acetylcholine; Animals; Brain; Cerebellum; Cerebral Cortex; Choline; Corpus Striatum; Female; Iodine Radioisotopes; Kinetics; Mice; Molecular Structure; Neurons; Phencyclidine; Piperidines; Stereoisomerism; Tetrahydronaphthalenes; Tritium

1990
Direct optical resolution of vesamicol and a series of benzovesamicol analogues by high-performance liquid chromatography.
    Journal of chromatography. A, 1994, Apr-29, Volume: 667, Issue:1-2

    Topics: 2-Naphthylamine; Cellulose; Chromatography, High Pressure Liquid; Indicators and Reagents; Iodine Radioisotopes; Phencyclidine; Piperidines; Spectrophotometry, Ultraviolet; Stereoisomerism; Tetrahydronaphthalenes

1994
In vivo mapping of cholinergic neurons in the human brain using SPECT and IBVM.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:3

    Topics: Adult; Alzheimer Disease; Animals; Brain; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Neurons; Phencyclidine; Piperidines; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

1994
Synthesis of the 123I- and 125I-labeled cholinergic nerve marker (-)-5-iodobenzovesamicol.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:8

    Topics: Animals; Brain; Chloramines; Cholinergic Fibers; Female; Hydrogen Peroxide; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Mice; Mice, Inbred Strains; Peracetic Acid; Phencyclidine; Piperidines; Stereoisomerism; Tetrahydronaphthalenes; Tissue Distribution; Tosyl Compounds

1993
Vesamicol receptor mapping of brain cholinergic neurons with radioiodine-labeled positional isomers of benzovesamicol.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Alzheimer Disease; Animals; Autoradiography; Binding, Competitive; Brain; Brain Mapping; Female; Guinea Pigs; Humans; Iodine Radioisotopes; Isomerism; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Neurons; Organ Specificity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Tetrahydronaphthalenes

1996
In vivo [125I]-iodobenzovesamicol binding reflects cortical cholinergic deficiency induced by specific immunolesion of rat basal forebrain cholinergic system.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:1

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Autoradiography; Cholinergic Fibers; Female; Iodine Radioisotopes; Piperidines; Prosencephalon; Radiography; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, sigma; Tetrahydronaphthalenes; Tissue Distribution

2000
Effects of long-term hormone therapy on cholinergic synaptic concentrations in healthy postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: Aged; Brain; Carrier Proteins; Estrogen Replacement Therapy; Estrogens; Female; Humans; Iodine Radioisotopes; Membrane Transport Proteins; Middle Aged; Organ Specificity; Piperidines; Postmenopause; Progestins; Reference Values; Regression Analysis; Synaptic Vesicles; Tetrahydronaphthalenes; Time Factors; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins

2001
Diminished striatal [123I]iodobenzovesamicol binding in idiopathic cervical dystonia.
    Annals of neurology, 2003, Volume: 53, Issue:4

    Topics: Adult; Aged; Carrier Proteins; Cholinergic Fibers; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Membrane Transport Proteins; Middle Aged; Piperidines; Tetrahydronaphthalenes; Tomography, Emission-Computed, Single-Photon; Torticollis; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins

2003
Decreased vesicular acetylcholine transporter and alpha(4)beta(2) nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning.
    Neuroscience letters, 2007, Mar-26, Volume: 415, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Azetidines; Brain; Female; Immunotoxins; Iodine Radioisotopes; N-Glycosyl Hydrolases; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Statistics, Nonparametric; Tetrahydronaphthalenes; Vesicular Acetylcholine Transport Proteins

2007
Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter.
    Synapse (New York, N.Y.), 2007, Volume: 61, Issue:12

    Topics: Animals; Autoradiography; Brain; Drug Interactions; Evaluation Studies as Topic; Isotope Labeling; Male; Papio; Piperidines; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Rats; Rats, Wistar; Tetrahydronaphthalenes; Time Factors; Tissue Distribution; Vesicular Acetylcholine Transport Proteins; Whole Body Imaging

2007
Comparison of noninvasive quantification methods of in vivo vesicular acetylcholine transporter using [123I]-IBVM SPECT imaging.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:9

    Topics: Aged; Brain; Dementia; Humans; Iodine Radioisotopes; Kinetics; Models, Biological; Piperidines; Radiopharmaceuticals; Tetrahydronaphthalenes; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins

2008
Correlation of the vesicular acetylcholine transporter densities in the striata to the clinical abilities of women with Rett syndrome.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:6

    Topics: Activities of Daily Living; Adult; Brain; Female; Humans; Male; Methyl-CpG-Binding Protein 2; Mutation; Piperidines; Rett Syndrome; Tetrahydronaphthalenes; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins

2012
Progressive supranuclear palsy: in vivo SPECT imaging of presynaptic vesicular acetylcholine transporter with [123I]-iodobenzovesamicol.
    Radiology, 2012, Volume: 265, Issue:2

    Topics: Aged; Brain; Female; Humans; Male; Piperidines; Presynaptic Terminals; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Supranuclear Palsy, Progressive; Tetrahydronaphthalenes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins

2012
123I-Iodobenzovesamicol SPECT Imaging of Cholinergic Systems in Dementia with Lewy Bodies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017, Volume: 58, Issue:1

    Topics: Aged; Aged, 80 and over; Brain; Cholinergic Neurons; Female; Humans; Lewy Body Disease; Male; Neural Pathways; Piperidines; Radiopharmaceuticals; Tetrahydronaphthalenes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Vesicular Acetylcholine Transport Proteins

2017