Compounds > 5-iodo-6-amino-1,2-benzopyrone
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5-iodo-6-amino-1,2-benzopyrone and warfarin

5-iodo-6-amino-1,2-benzopyrone has been researched along with warfarin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bauer, G; Bauer, PI; Buki, KG; Cole, GA; Hakam, A; Kirsten, E; Kun, E; Mendeleyev, J1
Bauer, PI; Comstock, JA; Hakam, A; Kirsten, E; Kun, E; Varadi, G; Young, LJ1
Cuzzocrea, S; Hake, P; Kun, E; O'Connor, MP; Salzman, A; Scott, GS; Szabó, C; Virág, L; Zingarelli, B1
Endres, M; Kun, E; Moskowitz, MA; Salzman, AL; Scott, GS; Szabó, C1
Kirsten, E; Kun, E1
Hake, P; Hooper, DC; Kean, RB; Scott, GS; Szabó, C; Virág, L1
Haskó, G; Kun, E; Mabley, JG; Rabinovitch, A; Salzman, AL; Suarez-Pinzon, WL; Szabó, C1
Deitch, EA; Forsythe, RM; Lu, Q; Xu, DZ1
Burke, NA; Carcillo, JA; Clark, RS; Du, L; Graham, SH; Han, YY; Kochanek, PM; Szabó, C; Watkins, SC; Zhang, X1
Clark, RS; Dixon, CE; Jenkins, LW; Kochanek, PM; Melick, J; Satchell, MA; Szabó, C; Zhang, X1
Cieślar-Pobuda, A; Ryabokon, NI; Rzeszowska-Wolny, J1
Cieślar-Pobuda, A; Rzeszowska-Wolny, J; Saenko, Y1
Back, OC; Jang, HS; Kim, DE; Kim, IS; Lee, JS; Lee, Y; Park, ES1

Other Studies

13 other study(ies) available for 5-iodo-6-amino-1,2-benzopyrone and warfarin

ArticleYear
Inhibition of HIV-1 IIIb replication in AA-2 and MT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyrone.
    Biochemical and biophysical research communications, 1991, Oct-31, Volume: 180, Issue:2

    Topics: Antiviral Agents; Cell Line; Coumarins; HIV-1; Humans; Kinetics; Ligands; Poly(ADP-ribose) Polymerase Inhibitors; Virus Replication

1991
Reversion of malignant phenotype by 5-iodo-6-amino-1,2-benzopyrone a non-covalently binding ligand of poly(ADP-ribose) polymerase.
    Biochimie, 1995, Volume: 77, Issue:5

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Transformation, Neoplastic; Cells, Cultured; Coumarins; Endothelium, Vascular; Genes, ras; Glycolysis; Humans; Ligands; Male; Mice; Mice, Nude; Phenotype; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured

1995
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-31, Volume: 95, Issue:7

    Topics: Animals; Arthritis; Coumarins; DNA Damage; Enzyme Inhibitors; Fibroblasts; Mice; Nitrates; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors

1998
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development.
    European journal of pharmacology, 1998, Jun-26, Volume: 351, Issue:3

    Topics: Animals; Cell Death; Cerebral Infarction; Coumarins; Enzyme Inhibitors; Ischemia; L-Lactate Dehydrogenase; Male; Mice; Mitochondria; Neuroglia; Neurons; Nitrates; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Tumor Cells, Cultured

1998
Cancer cell selectivity of 5-iodo-6-aminobenzopyrone (INH2BP) and methyl-3,5-diiodo-4(4'-methoxyphenoxy) benzoate (DIME).
    International journal of molecular medicine, 2000, Volume: 5, Issue:3

    Topics: Antineoplastic Agents; Benzamides; Cell Division; Cells, Cultured; Coumarins; Enzyme Inhibitors; Fibroblasts; Humans; Iodobenzoates; Phenyl Ethers; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured

2000
Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis.
    Journal of neuroimmunology, 2001, Jul-02, Volume: 117, Issue:1-2

    Topics: Animals; Coumarins; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Immunohistochemistry; Male; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Lew; Spinal Cord; Tyrosine

2001
Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Animals; Apoptosis; Blood Glucose; Cell Survival; Coumarins; Cytokines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genotype; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mutation; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Severity of Illness Index; Streptozocin; Tumor Cells, Cultured

2001
Lipopolysaccharide-induced enterocyte-derived nitric oxide induces intestinal monolayer permeability in an autocrine fashion.
    Shock (Augusta, Ga.), 2002, Volume: 17, Issue:3

    Topics: Animals; Bacterial Translocation; Cell Membrane Permeability; Cells, Cultured; Coumarins; Enterocytes; Enzyme Inhibitors; Intestines; Lipopolysaccharides; Lysine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Permeability; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; S-Nitroso-N-Acetylpenicillamine

2002
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.
    The Journal of biological chemistry, 2003, May-16, Volume: 278, Issue:20

    Topics: Animals; Apoptosis; Blotting, Western; Cell Death; Cell Nucleus; Coumarins; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Glutamic Acid; Immunohistochemistry; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; NAD; Neurons; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Time Factors

2003
A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.
    Journal of neurochemistry, 2003, Volume: 85, Issue:3

    Topics: 14-3-3 Proteins; Adenosine Diphosphate Ribose; Animals; Brain; Brain Injuries; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteins; Tyrosine 3-Monooxygenase

2003
Inhibition of poly(ADP-ribose) polymerase activity affects its subcellular localization and DNA strand break rejoining.
    Acta biochimica Polonica, 2009, Volume: 56, Issue:2

    Topics: Cell Line, Tumor; Cell Nucleus; Coumarins; DNA Breaks; DNA Repair; Enzyme Inhibitors; Humans; Isoquinolines; K562 Cells; Kinetics; Microscopy, Fluorescence; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Transport; Quinazolines; Quinolines

2009
PARP-1 inhibition induces a late increase in the level of reactive oxygen species in cells after ionizing radiation.
    Mutation research, 2012, Apr-01, Volume: 732, Issue:1-2

    Topics: Apoptosis; Coumarins; DNA Breaks, Double-Stranded; DNA Repair; G2 Phase Cell Cycle Checkpoints; Humans; Isoquinolines; K562 Cells; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinazolines; Reactive Oxygen Species; X-Rays

2012
The Protective Effect of INH2BP, a Novel PARP Inhibitor 5-Iodo-6-Amino-1,2-Benzopyrone, Against Hydrogen Peroxide-Induced Apoptosis Through ERK and p38 MAPK in H9c2 Cells.
    Pharmacology, 2015, Volume: 96, Issue:5-6

    Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Line; Cell Survival; Coumarins; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Myoblasts, Cardiac; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerase Inhibitors; Protective Agents; Rats; Reactive Oxygen Species

2015