5-iminodaunorubicin has been researched along with daunorubicin in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (77.78) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 3 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acton, EM; Henry, DW; Tong, GL | 1 |
| Glisson, BS; Killary, AM; Merta, P; Ross, WE; Siciliano, J; Siciliano, MJ | 1 |
| Capranico, G; Kohn, KW; Orr, A; Pommier, Y | 1 |
| Andreoni, A; Colasanti, A; Malatesta, V; Roberti, G | 1 |
| Borowski, E; Stefańska, B; Tarasiuk, J | 1 |
| Kolodziejczyk, P; Lown, JW; Reszka, K | 1 |
| Andreoni, A; Colasanti, A; Malatesta, V; Mastrocinque, M; Roberti, G; von Kisslinger, A | 1 |
| Bradley, MO; Kao-Shan, CS; Pommier, Y; Whang-Peng, J; Zwelling, LA | 1 |
| Davies, KJ; Doroshow, JH | 2 |
| Bredehorst, R; Panneerselvam, M; Vogel, CW | 1 |
| Muindi, JR; Myers, CE; Sinha, BK; Zweier, J | 1 |
| Andreoni, A; Malatesta, V | 1 |
| Ehrke, MJ; Maccubbin, DL; Mace, KF; Mihich, E; Taniguchi, N; Whitman, JA | 1 |
| Acton, EM | 1 |
| Fantine, EO; Garnier-Suillerot, A | 1 |
| Kohn, KW; Pommier, Y; Schwartz, RE; Zwelling, LA | 1 |
| Goormaghtigh, E; Pollakis, G; Praet, M; Ruysschaert, JM | 1 |
| Kerrigan, D; Minford, J; Nichols, M; Shackney, S; Zwelling, LA | 1 |
| Davies, KJ; Doroshow, JH; Hochstein, P | 1 |
| Delmelle, M; Goormaghtigh, E; Lion, Y; Pollakis, G; Ruysschaert, JM | 1 |
| Berg, H; Horn, G; Ihn, W; Tresselt, D | 1 |
| Acton, EM; Gordon, GR; Kashiwase, D; Peters, JH | 1 |
| Acton, EM; Jensen, RA; Peters, JH | 1 |
| Goormaghtigh, E; Pollakis, G; Ruysschaert, JM | 1 |
| Glazer, RI; Johnston, JB; Kerrigan, D; Lloyd, LS; Zwelling, LA | 1 |
| Kerrigan, D; Michaels, S; Zwelling, LA | 1 |
| Glazer, RI; Hartman, KD; Richardson, CL | 1 |
| Kerrigan, D; Pommier, Y; Schwartz, R; Zwelling, LA | 1 |
| Acton, EM; Tong, GL | 1 |
| Acton, EM; Evans, MJ; Jensen, RA; Peters, JH | 1 |
| Lowe, MC; Smallwood, JI | 1 |
| Henry, TR; Solem, LE; Wallace, KB | 1 |
| Boucek, RJ; Cusack, BJ; Fill, M; Gambliel, HA; Li, X; Mushlin, PS; Olson, RD; Palade, P; Shadle, SE | 1 |
| De Graff, WG; Hahn, SM; Mitchell, JB; Myers, LS | 1 |
| Britigan, BE; McCormick, ML; Reszka, KJ | 1 |
1 review(s) available for 5-iminodaunorubicin and daunorubicin
| Article | Year |
|---|---|
Anthracycline mechanisms in analogue selection.
Topics: Animals; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Humans; Neoplasms, Experimental; Structure-Activity Relationship | 1985 |
35 other study(ies) available for 5-iminodaunorubicin and daunorubicin
| Article | Year |
|---|---|
5-Iminodaunorubicin. Reduced cardiotoxic properties in an antitumor anthracycline.
Topics: Animals; Daunorubicin; DNA; DNA, Neoplasm; Heart Diseases; Leukemia L1210; Mice; Mutagens; Neoplasm Transplantation; Neoplasms, Experimental; Rats; RNA, Neoplasm | 1979 |
Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids.
Topics: Animals; CHO Cells; Chromosome Mapping; Chromosomes, Human, Pair 17; Colony-Forming Units Assay; Cricetinae; Daunorubicin; DNA Damage; DNA Topoisomerases, Type II; DNA, Single-Stranded; Doxorubicin; Etoposide; Genes; Humans; Hybrid Cells; Mitoxantrone | 1992 |
Distribution of topoisomerase II cleavage sites in simian virus 40 DNA and the effects of drugs.
Topics: Amsacrine; Animals; Base Sequence; Daunorubicin; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Viral; Ellipticines; Genome, Viral; Kinetics; Leukemia L1210; Mice; Molecular Sequence Data; Restriction Mapping; Simian virus 40; Substrate Specificity; Teniposide | 1991 |
Photocytotoxicity of anthracyclines upon laser excitation in their long-wavelength absorption bands.
Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; In Vitro Techniques; Photochemotherapy; Rats; Rats, Inbred F344 | 1991 |
Low stimulation of NADH oxidation and oxygen consumption by 5-iminodaunorubicin and its derivatives.
Topics: Animals; Carbohydrates; Daunorubicin; Electron Transport; Male; Microsomes, Liver; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains | 1990 |
Enzymatic oxidative activation of 5-iminodaunorubicin. Spectrophotometric and electron paramagnetic resonance studies.
Topics: Ascorbic Acid; Biotransformation; Daunorubicin; Electron Spin Resonance Spectroscopy; Horseradish Peroxidase; Hydrogen-Ion Concentration; Oxidation-Reduction; Spectrophotometry | 1989 |
Cell photosensitization by 5-iminodaunomycin activated with red light.
Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Radiation; In Vitro Techniques; Light; Photochemistry; Radiation-Sensitizing Agents; Rats; Thyroid Gland; Time Factors | 1989 |
Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells.
Topics: Aminoacridines; Amsacrine; Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Daunorubicin; DNA; DNA Topoisomerases, Type I; DNA, Single-Stranded; Intercalating Agents; Mutation; Sister Chromatid Exchange | 1985 |
Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.
Topics: Animals; Anthraquinones; Antibiotics, Antineoplastic; Cattle; Chemical Phenomena; Chemistry; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Methane; Mitochondria, Heart; Mitomycin; Mitomycins; Mitoxantrone; NAD; NADP; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rotenone; Superoxides | 1986 |
Doxorubicin enhances complement susceptibility of human melanoma cells by extracellular oxygen radical formation.
Topics: Catalase; Complement System Proteins; Daunorubicin; Doxorubicin; Free Radicals; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immunity, Cellular; Melanoma; Superoxide Dismutase; Superoxides | 1987 |
5-Iminodaunomycin. An anthracycline with unique properties.
Topics: Chemical Phenomena; Chemistry, Physical; Cyclic N-Oxides; Daunorubicin; DNA, Superhelical; DNA, Viral; Doxorubicin; Electron Spin Resonance Spectroscopy; Ferric Compounds; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Nitroso Compounds; Simian virus 40 | 1987 |
Dynamics of anthracyclines/DNA interaction: a laser time-resolved fluorescence study.
Topics: Chemical Phenomena; Chemistry; Daunorubicin; DNA; Lasers; Spectrometry, Fluorescence | 1988 |
Comparison of adriamycin induced immunomodulation with that of the noncardiotoxic anthracycline 5-iminodaunorubicin.
Topics: Adjuvants, Immunologic; Animals; Cell Line, Transformed; Daunorubicin; Doxorubicin; Female; Killer Cells, Natural; Mice; Mice, Inbred C57BL; Phagocytosis; Spleen; T-Lymphocytes, Cytotoxic | 1988 |
Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase.
Topics: Animals; Antibiotics, Antineoplastic; Antimycin A; Cattle; Cytochrome Reductases; Daunorubicin; Doxorubicin; Electron Transport; Free Radicals; Kinetics; Mitochondria, Heart; Models, Chemical; NAD; NADH Dehydrogenase; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rotenone; Succinates; Succinic Acid; Time Factors | 1986 |
Interaction of 5-iminodaunorubicin with Fe(III) and with cardiolipin-containing vesicles.
Topics: Cardiolipins; Circular Dichroism; Daunorubicin; Ferric Compounds; Hydrogen-Ion Concentration; Iron; Lipid Bilayers; Potentiometry; Spectrum Analysis | 1986 |
Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents.
Topics: Adenosine Triphosphate; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Daunorubicin; DNA; DNA Repair; DNA, Single-Stranded; Ellipticines; Intercalating Agents; Leukemia L1210; Magnesium; Mice; Sodium Chloride; Topoisomerase I Inhibitors | 1984 |
Damages of the mitochondrial membrane in Adriamycin treated mice.
Topics: Animals; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Electron Transport Complex IV; Enzyme Activation; Female; Intracellular Membranes; Lipid Peroxides; Male; Mice; Mitochondria, Heart; NADH Dehydrogenase | 1984 |
Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
Topics: Aminoacridines; Amsacrine; Animals; Bleomycin; Cell Survival; Cytarabine; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Synergism; Hydroxyurea; Intercalating Agents; Leukemia L1210; Mice | 1984 |
Mitochondrial NADH dehydrogenase-catalyzed oxygen radical production by adriamycin, and the relative inactivity of 5-iminodaunorubicin.
Topics: Animals; Cattle; Cytochrome Reductases; Daunorubicin; Doxorubicin; Free Radicals; Mitochondria, Heart; NADH Dehydrogenase; Oxidation-Reduction; Oxygen; Oxygen Consumption; Rotenone; Submitochondrial Particles; Superoxides | 1983 |
Adriamycin and derivatives interaction with the mitochondrial membrane: O2 consumption and free radicals formation.
Topics: Animals; Benzoquinones; Cattle; Daunorubicin; Intracellular Membranes; Mitochondria, Heart; NADH Dehydrogenase; Oxygen Consumption; Quinones | 1984 |
[Electrochemical reduction of the anthracycline antibiotic 5-iminodaunorubicin. Isolation and structural clarification of the reduction products].
Topics: Daunorubicin; Electrochemistry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Polarography; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1984 |
Metabolic disposition of 5-iminodaunorubicin in the rat.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Daunorubicin; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Electrocardiographic and transmembrane potential effects of 5-iminodaunorubicin in the rat.
Topics: Animals; Daunorubicin; Electrocardiography; Female; Heart; Heart Ventricles; Membrane Potentials; Microelectrodes; Microscopy, Electron; Myocardium; Rats; Rats, Inbred Strains | 1984 |
Role of the quinone structure in the mitochondrial damage induced by antitumor anthracyclines. Comparison of adriamycin and 5-iminodaunorubicin.
Topics: Animals; Cattle; Daunorubicin; Doxorubicin; Electron Transport; Fluorescence Polarization; In Vitro Techniques; Intracellular Membranes; Mitochondria, Heart; Quinones; Structure-Activity Relationship | 1983 |
Comparison of DNA scission and cytotoxicity produced by Adriamycin and 5-iminodaunorubicin in human colon carcinoma cells.
Topics: Cell Survival; Cells, Cultured; Colonic Neoplasms; Daunorubicin; DNA; DNA Repair; DNA, Single-Stranded; Dose-Response Relationship, Drug; Doxorubicin; Humans; Kinetics | 1983 |
Cytotoxicity and DNA strand breaks by 5-iminodaunorubicin in mouse leukemia L1210 cells: comparison with adriamycin and 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Topics: Aminoacridines; Amsacrine; Animals; Cell Survival; Cells, Cultured; Daunorubicin; DNA; Doxorubicin; Leukemia L1210; Mice | 1982 |
Cytokinetic and biochemical effects of 5-iminodaunorubicin in human colon carcinoma in culture.
Topics: Cell Survival; Cells, Cultured; Colonic Neoplasms; Daunorubicin; DNA, Neoplasm; Doxorubicin; Humans; Molecular Weight; Neoplasms, Experimental; RNA, Neoplasm | 1982 |
The formation and resealing of intercalator-induced DNA strand breaks in isolated L1210 cell nuclei.
Topics: Aminacrine; Animals; Cell Nucleus; Daunorubicin; DNA Repair; Ellipticines; Kinetics; Leukemia L1210; Mice | 1982 |
Synthesis and preliminary antitumor evaluation of 5-iminodoxorubicin.
Topics: Animals; Antineoplastic Agents; Daunorubicin; Doxorubicin; Leukemia P388; Mice | 1981 |
Effects of 5-iminodaunorubicin on nucleoli of rats.
Topics: Animals; Cell Nucleolus; Daunorubicin; Liver; Male; Myocardium; Rats | 1980 |
Adriamycin and daunomycin dose-dependent effects upon contractions of isolated rat myocytes.
Topics: Animals; Cells, Cultured; Daunorubicin; Depression, Chemical; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Humans; Male; Myocardial Contraction; Myocardium; Rats | 1980 |
Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration.
Topics: Analysis of Variance; Animals; Body Weight; Calcium; Cyclosporine; Daunorubicin; Doxorubicin; Homeostasis; Male; Membrane Potentials; Mitochondria, Heart; Mitochondrial Swelling; Organ Size; Oxygen Consumption; Rats; Rats, Inbred F344; Ruthenium Red; Time Factors | 1994 |
Sarcoplasmic reticulum calcium release is stimulated and inhibited by daunorubicin and daunorubicinol.
Topics: Animals; Antibiotics, Antineoplastic; Caffeine; Calcium; Daunorubicin; Dithiothreitol; Dogs; Female; In Vitro Techniques; Male; Microsomes; Sarcoplasmic Reticulum; Sulfhydryl Reagents | 2000 |
Protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity by 3,4-dihydroxybenzoic acid.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Daunorubicin; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Electrophoresis, Agar Gel; Free Radicals; Hydroxybenzoates; Oxidation-Reduction; Topoisomerase II Inhibitors | 2003 |
Oxidation of anthracycline anticancer agents by the peroxidase mimic microperoxidase 11 and hydrogen peroxide.
Topics: Animals; Antibiotics, Antineoplastic; Cytochrome c Group; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Heart; Horses; Hydrogen Peroxide; Hydroquinones; Oxidants; Oxidation-Reduction; Peroxidases; Spectrophotometry | 2003 |