Compounds > 5-hydroxyuracil
Page last updated: 2024-08-25

5-hydroxyuracil and uracil

5-hydroxyuracil has been researched along with uracil in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.17)18.7374
1990's8 (17.39)18.2507
2000's22 (47.83)29.6817
2010's12 (26.09)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Ho, YS; Lin, JK; Lo, MJ; Wang, YJ1
Kow, YW; Purmal, AA; Wallace, SS1
Halliwell, B; Kaur, H1
Fujimoto, J; Sowers, LC; Tran, L1
Buckley, TJ; Dizdaroglu, M; Karahalil, B; Roldán-Arjona, T; Sentürker, S1
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R1
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R1
Fukuoka, M; Inoue, H; Ohtsuka, E; Terashima, Y1
Asagoshi, K; Ide, H; Miyano, T; Nakano, H; Odawara, H; Ohyama, Y; Seki, S; Terato, H1
Burgess, S; Dizdaroglu, M; Dodson, ML; Jaruga, P; Lloyd, RS1
Dawson, R; Messina, SA1
Boldogh, I; Hatahet, Z; Hazra, TK; Imhoff, B; Izumi, T; Kow, YW; Mitra, S; Mokkapati, SK1
Kow, YW1
DUNCAN, RE; SCHREIBER, RW1
Dou, H; Hazra, TK; Mitra, S1
Das, A; Hazra, TK; Mathura, VS; Mitra, S; Rajagopalan, L; Rigby, SJ1
Ide, H; Izumi, S; Katayanagi, K; Matsubara, M; Ohmae, E; Tanaka, T; Terato, H1
Gorenstein, DG; Somasunderam, A; Thiviyanathan, V; Volk, DE2
Eon-Marchais, S; Eot-Houllier, G; Gasparutto, D; Sage, E1
Dean, W; Fischer-Colbrie, R; Gordon, E; Gritsch, S; Humby, T; Isles, AR; Kelsey, G; Plagge, A; Wilkinson, LS1
Dianov, GL; Parsons, JL; Zharkov, DO1
Lee, CY; Li, L; Li, X; Lu, AL1
Cadet, J; Favier, A; Gambarelli, S; Gasparutto, D; Saint-Pierre, C; Simon, P1
Charlet-Berguerand, N; Conaway, JW; Conaway, R; Egly, JM; Feuerhahn, S; Kong, SE; Ziserman, H1
Dianov, GL; O'Connor, TR; Parsons, JL; Preston, BD1
Dianov, GL; Kavli, B; Parsons, JL; Slupphaug, G1
Eot-Houllier, G; Gasparutto, D; Giustranti, C; Gonera, M; Sage, E1
Gorenstein, DG; Hazra, TK; Mitra, S; Somasunderam, A; Thiviyanathan, V; Volk, DE1
Bohr, VA; Bukowy, Z; Harrigan, JA; Ramsden, DA; Stevnsner, T; Tudek, B1
Bjørås, M; Brinchmann, JE; Duggal, S; Hildrestrand, GA; Luna, L1
Aamann, MD; Berquist, BR; Bohr, VA; de Souza-Pinto, NC; Hvitby, C; Muftuoglu, M; Scheibye-Knudsen, M; Sorensen, MM; Stevnsner, T; Tian, J; Wilson, DM1
Hazra, TK; Hegde, ML; Mitra, S; Theriot, CA1
Bohr, VA; Croteau, DL; Popuri, V1
Amorati, R; Chatgilialoglu, C; Grabovskiy, SA; Kabal'nova, NN; Pedulli, GF; Valgimigli, L1
Averill, A; Doublié, S; Imamura, K; Wallace, SS1
Radicella, JP; Sage, E; Sedletska, Y1
Bohr, VA; Canugovi, C; Croteau, DL; Shamanna, RA1
Azéma, J; Legay, R; Malet-Martino, M; Martino, R; Massou, S1
Katahira, M; Mashima, T; Nishiyama, K; Shionoya, M; Takezawa, Y1
Goto, M; Kato, H; Kawanishi, Y; Misawa, K; Nakamura, S; Shinmura, K; Sugimura, H; Tao, H; Yoshimura, K1
Albelazi, MS; Elder, RH; Martin, PR; Mohammed, S; Mutti, L; Parsons, JL1
Brabec, V; Hrabina, O; Novakova, O1
Iwai, S; Shiraishi, M1
Mori, K; Nishiyama, K; Shionoya, M; Takezawa, Y1
Anderson-Steele, BM; David, SS; Lotsof, ER; Yeo, J1

Reviews

1 review(s) available for 5-hydroxyuracil and uracil

ArticleYear
Repair of deaminated bases in DNA.
    Free radical biology & medicine, 2002, Oct-01, Volume: 33, Issue:7

    Topics: Animals; Base Pair Mismatch; DNA; DNA Repair; Humans; Pentoxyl; Purines; Pyrimidines; Uracil

2002

Trials

1 trial(s) available for 5-hydroxyuracil and uracil

ArticleYear
Oxidative DNA base damage in lymphocytes of HIV-infected drug users.
    Free radical research, 1999, Volume: 31, Issue:3

    Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil

1999

Other Studies

44 other study(ies) available for 5-hydroxyuracil and uracil

ArticleYear
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
    Chemico-biological interactions, 1995, Volume: 94, Issue:2

    Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Liver; Liver Neoplasms, Experimental; Lung; Lung Neoplasms; Male; Methylamines; Nitrates; Oxidation-Reduction; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thymine; Uracil

1995
Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.
    Nucleic acids research, 1994, Jan-11, Volume: 22, Issue:1

    Topics: Base Sequence; Cytosine; DNA; DNA Polymerase I; Escherichia coli; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidation-Reduction; Substrate Specificity; Templates, Genetic; Uracil

1994
Measurement of oxidized and methylated DNA bases by HPLC with electrochemical detection.
    The Biochemical journal, 1996, Aug-15, Volume: 318 ( Pt 1)

    Topics: Chromatography, High Pressure Liquid; DNA; DNA Damage; Electrochemistry; Guanine; Methylation; Oxidation-Reduction; Purines; Pyrimidines; Uracil

1996
Synthesis and cleavage of oligodeoxynucleotides containing a 5-hydroxyuracil residue at a defined site.
    Chemical research in toxicology, 1997, Volume: 10, Issue:11

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Hydrolysis; Indicators and Reagents; Oligonucleotides; Spectrophotometry, Ultraviolet; Uracil

1997
Excision of products of oxidative DNA base damage by human NTH1 protein.
    Biochemistry, 1999, Jan-05, Volume: 38, Issue:1

    Topics: Barbiturates; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Humans; Kinetics; Oxidation-Reduction; Substrate Specificity; Thymine; Uracil

1999
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms

1998
Further studies of KMnO4 oxidation of synthetic DNAs containing oxidatively damaged bases.
    Nucleic acids symposium series, 1999, Issue:42

    Topics: Adenine; Base Sequence; DNA; DNA Damage; Guanine; Oligodeoxyribonucleotides; Oxidation-Reduction; Potassium Permanganate; Uracil

1999
Comparison of substrate specificities of Escherichia coli endonuclease III and its mouse homologue (mNTH1) using defined oligonucleotide substrates.
    Biochemistry, 2000, Sep-19, Volume: 39, Issue:37

    Topics: Animals; Base Pairing; Borohydrides; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; Endodeoxyribonucleases; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Mice; Oligonucleotides; Oligopeptides; Schiff Bases; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Thymine; Uracil; Urea

2000
Determination of active site residues in Escherichia coli endonuclease VIII.
    The Journal of biological chemistry, 2002, Jan-25, Volume: 277, Issue:4

    Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Deoxyribonuclease (Pyrimidine Dimer); DNA Primers; Dose-Response Relationship, Drug; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Thymine; Uracil

2002
Attenuation of oxidative damage to DNA by taurine and taurine analogs.
    Advances in experimental medicine and biology, 2000, Volume: 483

    Topics: Adenine; Animals; Antioxidants; Cattle; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Hydrogen Peroxide; Oxidants; Oxidative Stress; Structure-Activity Relationship; Taurine; Uracil

2000
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions.
    The Journal of biological chemistry, 2002, Aug-23, Volume: 277, Issue:34

    Topics: Cell Cycle; Cell Nucleus; Cytosine; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Humans; N-Glycosyl Hydrolases; Organ Specificity; Recombinant Proteins; Uracil

2002
A cytological analysis of the antimetabolite activity of 5-hydroxyuracil in Vicia faba roots.
    The Journal of biophysical and biochemical cytology, 1958, Nov-25, Volume: 4, Issue:6

    Topics: Antimetabolites; Cell Nucleus; DNA; DNA Replication; Fabaceae; Mitosis; Plant Roots; Thymidine; Thymine; Uracil; Uridine; Vicia faba

1958
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2.
    The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50

    Topics: Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Glycosylases; DNA Repair; DNA Replication; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Single-Stranded; Dose-Response Relationship, Drug; Escherichia coli; Humans; Kinetics; Models, Chemical; Mutation; Nucleic Acid Conformation; Oligonucleotides; Oxygen; Transcription, Genetic; Uracil

2003
Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Blotting, Western; Circular Dichroism; Cysteine; DNA; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Escherichia coli; Histidine; Humans; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Peptides; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Uracil; Zinc; Zinc Fingers

2004
Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase.
    Nucleic acids research, 2004, Volume: 32, Issue:17

    Topics: Amino Acid Sequence; Catalysis; DNA Damage; DNA Glycosylases; DNA Mutational Analysis; DNA Repair; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentoxyl; Structural Homology, Protein; Uracil; Uracil-DNA Glycosidase; Xenopus Proteins

2004
5-hydroxyuracil can form stable base pairs with all four bases in a DNA duplex.
    Chemical communications (Cambridge, England), 2005, Jan-21, Issue:3

    Topics: Base Pairing; DNA; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleosides; Oxidation-Reduction; Uracil

2005
Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins.
    Nucleic acids research, 2005, Volume: 33, Issue:1

    Topics: Bacteria; Cell Extracts; Cell Line, Transformed; DNA Damage; DNA Repair; DNA Repair Enzymes; Guanine; Humans; Radiation, Ionizing; Uracil

2005
Imprinted Nesp55 influences behavioral reactivity to novel environments.
    Molecular and cellular biology, 2005, Volume: 25, Issue:8

    Topics: Adaptation, Psychological; Animals; Behavior, Animal; Brain Chemistry; Chromogranins; Dopamine; Female; Genomic Imprinting; GTP-Binding Protein alpha Subunits, Gs; Locus Coeruleus; Male; Mice; Mice, Mutant Strains; Norepinephrine; Risk-Taking; Uracil

2005
NEIL1 excises 3' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1.
    Nucleic acids research, 2005, Volume: 33, Issue:15

    Topics: Base Sequence; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Oligonucleotides; Oxidative Stress; Substrate Specificity; Uracil

2005
Physical and functional interactions between Escherichia coli MutY and endonuclease VIII.
    The Biochemical journal, 2006, Jan-01, Volume: 393, Issue:Pt 1

    Topics: Deoxyribonuclease (Pyrimidine Dimer); DNA Glycosylases; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Guanine; Protein Binding; Protein Conformation; Uracil

2006
Ab initio base-pairing energies of uracil and 5-hydroxyuracil with standard DNA bases at the BSSE-free DFT and MP2 theory levels.
    Organic & biomolecular chemistry, 2006, May-07, Volume: 4, Issue:9

    Topics: Adenine; Base Pairing; Cytosine; DNA; Guanine; Models, Molecular; Thymine; Uracil

2006
Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repair.
    Nucleic acids research, 2006, Volume: 34, Issue:13

    Topics: DNA Damage; DNA Glycosylases; DNA Repair; Electron Spin Resonance Spectroscopy; Electrons; Hydantoins; Nucleosides; Oligodeoxyribonucleotides; Oxidation-Reduction; Pentoses; Substrate Specificity; Uracil

2006
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.
    The EMBO journal, 2006, Nov-29, Volume: 25, Issue:23

    Topics: DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Elongin; Guanine; HeLa Cells; Humans; Oxidative Stress; Poly-ADP-Ribose Binding Proteins; RNA Polymerase II; Thymine; Transcription Factors; Transcription Factors, TFII; Transcription, Genetic; Transcriptional Elongation Factors; Uracil

2006
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.
    Nucleic acids research, 2007, Volume: 35, Issue:4

    Topics: Animals; Cells, Cultured; DNA Breaks, Single-Stranded; DNA Ligases; DNA Polymerase beta; DNA Polymerase III; DNA Repair; Exodeoxyribonucleases; HeLa Cells; Humans; Hypoxanthine; Mice; Mutation; Uracil

2007
NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break.
    Biochemistry, 2007, Apr-03, Volume: 46, Issue:13

    Topics: DNA Damage; DNA Glycosylases; DNA Ligase ATP; DNA Ligases; DNA Polymerase beta; DNA Repair; Humans; Poly-ADP-Ribose Binding Proteins; Uracil; Uracil-DNA Glycosidase; Xenopus Proteins

2007
Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences.
    Nucleic acids research, 2007, Volume: 35, Issue:10

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; DNA Breaks, Double-Stranded; DNA Damage; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Guanine; Humans; Uracil

2007
Base-pairing properties of the oxidized cytosine derivative, 5-hydroxy uracil.
    Biochemical and biophysical research communications, 2008, Feb-15, Volume: 366, Issue:3

    Topics: Base Pairing; Computer Simulation; Cytosine; DNA; Models, Chemical; Models, Molecular; Oxidation-Reduction; Uracil

2008
WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.
    Nucleic acids research, 2008, Volume: 36, Issue:15

    Topics: Antigens, Nuclear; Cytosine; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Exodeoxyribonucleases; Humans; Ku Autoantigen; Oxidative Stress; RecQ Helicases; Uracil; Werner Syndrome Helicase

2008
Modulation of DNA glycosylase activities in mesenchymal stem cells.
    Experimental cell research, 2009, Sep-10, Volume: 315, Issue:15

    Topics: Adipose Tissue; Animals; Cells, Cultured; DNA Damage; DNA Glycosylases; DNA Repair; Gene Expression Profiling; Guanine; Humans; Immunophenotyping; Mesenchymal Stem Cells; Oligonucleotide Array Sequence Analysis; Uracil

2009
Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:7

    Topics: Cell Line; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA, Mitochondrial; Guanine; Humans; Mitochondrial Membranes; Oxidative Stress; Poly-ADP-Ribose Binding Proteins; Uracil

2010
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures.
    DNA repair, 2010, Jun-04, Volume: 9, Issue:6

    Topics: Base Sequence; Cell Nucleus; DNA; DNA Breaks, Single-Stranded; DNA Damage; DNA Glycosylases; DNA Primers; Electrophoretic Mobility Shift Assay; HeLa Cells; Humans; Oxidative Stress; Proliferating Cell Nuclear Antigen; Protein Binding; Replication Protein A; Substrate Specificity; Uracil

2010
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases.
    DNA repair, 2010, Jun-04, Volume: 9, Issue:6

    Topics: Base Sequence; DNA; DNA Damage; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Exodeoxyribonucleases; Humans; Oligodeoxyribonucleotides; Oxidative Stress; Protein Binding; Pyrimidines; RecQ Helicases; Substrate Specificity; Uracil; Werner Syndrome Helicase

2010
Base-promoted reaction of 5-hydroxyuracil derivatives with peroxyl radicals.
    Organic letters, 2010, Sep-17, Volume: 12, Issue:18

    Topics: Molecular Structure; Oxygen; Peroxides; Uracil

2010
Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA.
    The Journal of biological chemistry, 2012, Feb-03, Volume: 287, Issue:6

    Topics: Catalytic Domain; Crystallography, X-Ray; DNA; DNA Glycosylases; Humans; Mimiviridae; Oxidation-Reduction; Thymine; Uracil

2012
Replication fork collapse is a major cause of the high mutation frequency at three-base lesion clusters.
    Nucleic acids research, 2013, Volume: 41, Issue:20

    Topics: Cell Line, Transformed; Deoxyribonuclease (Pyrimidine Dimer); DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; DNA Replication; Escherichia coli Proteins; Guanine; Humans; Mutagenesis; Mutation Rate; Uracil

2013
Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Dideoxynucleotides; DNA Damage; DNA Ligases; DNA Repair; DNA, Mitochondrial; Humans; Middle Aged; Mitochondria; Oxidative Stress; Uracil

2014
Hydrolytic pathway of 5-fluorouracil in aqueous solutions for clinical use.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Chemistry, Pharmaceutical; Fluorouracil; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Sodium Hydroxide; Solutions; Uracil

2014
Bifacial Base-Pairing Behaviors of 5-Hydroxyuracil DNA Bases through Hydrogen Bonding and Metal Coordination.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Oct-12, Volume: 21, Issue:42

    Topics: Base Pairing; Coordination Complexes; DNA; Gadolinium; Hydrogen Bonding; Ions; Uracil

2015
Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5-hydroxyuracil, an oxidation product of cytosine.
    Free radical biology & medicine, 2019, 02-01, Volume: 131

    Topics: Adenomatous Polyposis Coli; Alleles; Cell Line, Tumor; Colorectal Neoplasms; Deoxyribonuclease (Pyrimidine Dimer); DNA Cleavage; DNA Glycosylases; DNA Mutational Analysis; DNA Repair; Epithelial Cells; Gene Expression; Humans; Mutation; Uracil; Uracil-DNA Glycosidase

2019
The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks.
    Genes, 2019, 04-23, Volume: 10, Issue:4

    Topics: Cell Cycle; DNA; DNA Glycosylases; DNA Replication; DNA, Single-Stranded; Humans; Models, Genetic; N-Glycosyl Hydrolases; Thymine; Uracil

2019
Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis.
    International journal of molecular sciences, 2019, Oct-10, Volume: 20, Issue:20

    Topics: DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; HIV-1; Humans; Mutagens; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Thermodynamics; Uracil

2019
Molecular Basis of Substrate Recognition of Endonuclease Q from the Euryarchaeon Pyrococcus furiosus.
    Journal of bacteriology, 2020, 01-02, Volume: 202, Issue:2

    Topics: Archaeal Proteins; DNA Repair; Endonucleases; Pyrococcus furiosus; Substrate Specificity; Uracil

2020
Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases.
    Chemical communications (Cambridge, England), 2021, Mar-09, Volume: 57, Issue:20

    Topics: Base Sequence; Cations; DNA; Gadolinium; Hydrogen Bonding; Nucleic Acid Conformation; Oligonucleotides; Phase Transition; Uracil

2021
RNA Editing of the Human DNA Glycosylase NEIL1 Alters Its Removal of 5-Hydroxyuracil Lesions in DNA.
    Biochemistry, 2021, 05-18, Volume: 60, Issue:19

    Topics: DNA; DNA Glycosylases; DNA Repair; DNA, Single-Stranded; Humans; Oxidation-Reduction; RNA Editing; Thymine; Uracil

2021