5-hydroxytryptophan and probenecid

5-hydroxytryptophan has been researched along with probenecid in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (97.56)	18.7374
1990's	1 (2.44)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ	1
Butler, IJ; Koslow, SH	1
Korf, J; Sebens, JB; van Wijk, M	1
Deshmukh, VD; Haufrect, DB; Jacob, RH; Mathew, NT; Meyer, JS; Morrell, RM; Perez, FI; Welch, KM	1
MacMillan, V	2
Ahtee, L; Carlsson, A	1
Fukushima, H; Kitagawa, S; Nakamura, M	1
Sethy, VH; Van Woert, MH	1
Stancer, HC; Warsh, JJ	2
Ritzmann, RF; Tabakoff, B	1
Jacoby, JH; MacKenzie, RG; Trulson, ME	1
Bednar, I; Forsberg, G; Qureshi, GA; Södersten, P	1
Bermúdez, M; Fuenmayor, LD	1
Carlsson, A; Davis, JN	1
Bourgoin, S; Glowinski, J; Hamon, M; Ley, JP; Morot-Gaudry, Y	1
Bédard, P; Carlsson, A; Lindqvist, M	1
Gardey-Levassort, C; Lechat, P; Olive, G; Sadeghi, D	1
Chase, TN	1
Gardey-Levassort, C; Lechat, P; Olive, G	1
Bensinger, RE; Klein, DC; Lovenberg, W; Weller, JL	1
Dols, LC; Korf, J; Schut, T; van Praag, HM	1
Korf, J; van Praag, HM	2
Costa, E; Diaz, PM; Ngai, SH	1
Sanders-Bush, E; Sulser, F	1
Downer, RG; Sloley, BD	1
Boissier, JR; Euvrard, C	1
de Haan, S; van Praag, HM	2
Benezech, M; Bioulac, B; Noel, B; Renaud, B; Roche, D	1
Hedner, T; Lundborg, P	1
Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Pujol, JF; Riou, F	1
Trulson, ME; Trulson, VM	1
Lamour, Y; Ory-Lavollee, L; Pointis, D; Rivot, JP	1
Buchle, AM; Fehr, B; Feldtrauer, JJ; Stoecklin, K; Waldmeier, PC	1
van Praag, HM	1
Deiman-Van Aalst, WM; Eigeman, L; Vaatstra, WJ	1
Huot, S; Palfreyman, MG; Wagner, J	1
Pinto-do-O, PC; Soares-da-Silva, P	1

Reviews

3 review(s) available for 5-hydroxytryptophan and probenecid

Article	Year
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle. Biological psychiatry, 1976, Volume: 11, Issue:4 Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception	1976
Serotonergic mechanisms and extrapyramidal function in man. Advances in neurology, 1974, Volume: 5 Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors	1974
Central serotonin deficiency--a factor which increases depression vulnerability? Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280 Topics: 5-Hydroxytryptophan; Adult; Biogenic Amines; Brain Chemistry; Clomipramine; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Serotonin	1980

Trials

3 trial(s) available for 5-hydroxytryptophan and probenecid

Article	Year
A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant. Psychopharmacologia, 1972, Volume: 25, Issue:1 Topics: 5-Hydroxytryptophan; Brain; Clinical Trials as Topic; Depression; Humans; Placebos; Probenecid; Serotonin; Spinal Puncture	1972
5-Hydroxytrytophan as an antidepressant. The predictive value of the probenecid test. The Journal of nervous and mental disease, 1974, Volume: 158, Issue:5 Topics: 5-Hydroxytryptophan; Biological Transport; Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Hydroxyindoleacetic Acid; Pilot Projects; Probenecid; Psychological Tests; Remission, Spontaneous; Serotonin	1974
Serotonin metabolism in depression: clinical application of the probenecid test. International pharmacopsychiatry, 1974, Volume: 9, Issue:1 Topics: 5-Hydroxytryptophan; Adjustment Disorders; Administration, Oral; Clinical Trials as Topic; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Injections, Intravenous; Intestinal Absorption; Placebos; Probenecid; Psychiatric Status Rating Scales; Serotonin; Time Factors	1974

Other Studies

35 other study(ies) available for 5-hydroxytryptophan and probenecid

Article	Year
Biogenic amine synthesis defect in dihydropteridine reductase deficiency. Science (New York, N.Y.), 1977, Nov-04, Volume: 198, Issue:4316 Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine	1977
Probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan. Psychopharmacology, 1979, Feb-28, Volume: 60, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Blood-Brain Barrier; Brain; Brain Chemistry; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tryptophan	1979
Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. Journal of the American Geriatrics Society, 1977, Volume: 25, Issue:7 Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurocognitive Disorders; Probenecid; Serotonin; Tyrosine	1977
The effects of acute hypercapnia on cerebral indole amine metabolism. Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:2 Topics: 5-Hydroxytryptophan; Amines; Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Hypercapnia; Indoles; Male; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1978
Dual action of methadone on 5-HT synthesis and metabolism. Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine	1979
Effects of amitriptyline and isocarboxazid on 5-hydroxytryptophan induced head twitches in mice. Psychopharmacology, 1976, Jul-09, Volume: 48, Issue:1 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Behavior, Animal; Brain Chemistry; Drug Interactions; Humans; Hydroxyindoleacetic Acid; Isocarboxazid; Male; Mice; Probenecid; Serotonin; Stereotyped Behavior	1976
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. Neurology, 1975, Volume: 25, Issue:2 Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin	1975
The origin of blood k-hydroxyindoleacetic acid following L-hydrazino-alpha-methyldopa (MK-486). European journal of pharmacology, 1975, Volume: 32, Issue:1 Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin	1975
The origin of blood 5-hydroxyindoleacetic acid following L-hydrazine-alpha-methyldopa (MK-486). European journal of pharmacology, 1975, Volume: 32, Issue:1 Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin	1975
Ethanol, serotonin metabolism, and body temperature. Annals of the New York Academy of Sciences, 1976, Volume: 273 Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Central Nervous System; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Humans; Mice; Probenecid; Serotonin; Substance Withdrawal Syndrome	1976
Streptozotocin-induced diabetes reduces brain serotonin synthesis in rats. Journal of neurochemistry, 1986, Volume: 46, Issue:4 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Carboxy-Lyases; Diabetes Mellitus, Experimental; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin	1986
A comparison of the effects of carbon monoxide intoxication and low-oxygen gas mixtures on cerebral biogenic amine metabolism. Brain research, 1987, Apr-07, Volume: 408, Issue:1-2 Topics: 5-Hydroxytryptophan; Animals; Carbon Monoxide Poisoning; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin	1987
Tryptophan, 5-HTP, 5-HT and 5-HIAA in the cerebrospinal fluid and sexual behavior in male rats. Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2 Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Homovanillic Acid; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Sexual Behavior, Animal; Tryptophan	1989
Effect of the cerebral tryptaminergic system on the turnover of dopamine in the striatum of the rat. Journal of neurochemistry, 1985, Volume: 44, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Dopamine; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin	1985
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain. Journal of neurochemistry, 1973, Volume: 21, Issue:4 Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Kinetics; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Probenecid; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1973
Estimation of the rate of 5-HT synthesis in the mouse brain by various methods. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:3 Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Chromatography, Ion Exchange; Female; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Mice; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Serotonin; Spectrometry, Fluorescence; Tritium; Tryptophan	1974
Effect of a transverse cerebral hemisection on 5-hydroxytryptamine metabolism in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 272, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carboxy-Lyases; Diencephalon; Female; Hydrazines; Hydroxyindoleacetic Acid; Male; Mesencephalon; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tryptophan	1972
Action of probenecid on the central nervous system of the rabbit. I. Effects on the elimination of 5-hydroxyindoleacetic acid. Pharmacology, 1973, Volume: 9, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Biological Transport, Active; Brain Stem; Central Nervous System; Cerebral Cortex; Fenclonine; Hydroxyindoleacetic Acid; Hypothalamus; Male; Probenecid; Rabbits; Serotonin; Serotonin Antagonists	1973
Action of probenecid on the central nervous system of the rabbit. II. Potentiation of 5-hydroxytryptophan-induced hyperthermia and suppression of this effect by a decarboxylase inhibitor (Ro4-4602). Pharmacology, 1974, Volume: 11, Issue:5 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Body Temperature; Brain Chemistry; Brain Stem; Drug Synergism; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus; Male; Probenecid; Rabbits; Serotonin	1974
Radiometric assay of total tryptophan hydroxylation by intact cultured pineal glands. Journal of neurochemistry, 1974, Volume: 23, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Cycloheximide; Evaluation Studies as Topic; Female; Isoproterenol; Kinetics; Male; Melatonin; Mescaline; Methods; Mixed Function Oxygenases; Organ Culture Techniques; Phenylalanine; Pineal Gland; Probenecid; Rats; Serotonin; Species Specificity; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase	1974
Effect of oxygen on brain serotonin metabolism in rats. The American journal of physiology, 1968, Volume: 214, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Brain; Hydroxyindoleacetic Acid; Kinetics; Male; Mixed Function Oxygenases; Oxygen; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1968
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Phenylalanine; Probenecid; Quinolizines; Rats; Reserpine; Serotonin; Tritium; Tryptophan	1970
Distribution of 5-hydroxytryptamine and indolealkylamine metabolites in the American cockroach, Periplaneta americana L. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Cockroaches; Dopamine; Ganglia; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Mitochondria; Monoamine Oxidase; Probenecid; Rats; Reserpine; Serotonin; Species Specificity; Succinate Dehydrogenase; Tryptophan	1984
Biochemical assessment of the central 5-HT agonist activity of RU 24969 (a piperidinyl indole). European journal of pharmacology, 1980, Apr-11, Volume: 63, Issue:1 Topics: 5-Hydroxytryptophan; Adenylyl Cyclases; Animals; Animals, Newborn; Brain Chemistry; Corticosterone; Hydroxyindoleacetic Acid; Indoles; Male; Pituitary Gland; Probenecid; Prolactin; Rats; Receptors, Serotonin; Serotonin	1980
Serotoninergic dysfunction in the 47, XYY syndrome. Biological psychiatry, 1980, Volume: 15, Issue:6 Topics: 5-Hydroxytryptophan; Adult; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Serotonin; Sex Chromosome Aberrations; XYY Karyotype	1980
Serotoninergic development in the postnatal rat brain. Journal of neural transmission, 1980, Volume: 49, Issue:4 Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Benzyl Alcohols; Brain; Clomipramine; Hydrazines; Hydroxyindoleacetic Acid; Probenecid; Rats; Serotonin; Tryptophan	1980
Chemoprophylaxis of depressions. An attempt to compare lithium with 5-hydroxytryptophan. Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290 Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Recurrence; Serotonin	1981
Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindoleacetic acid in the rat striatum. Brain research, 1981, Nov-02, Volume: 223, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Benzyl Alcohols; Clorgyline; Corpus Striatum; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan	1981
Reduction in brain serotonin synthesis rate following chronic methamphetamine administration in rats. European journal of pharmacology, 1982, Sep-10, Volume: 83, Issue:1-2 Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benserazide; Brain; Fluoxetine; Hydroxyindoleacetic Acid; Male; Methamphetamine; Probenecid; Rats; Rats, Inbred Strains; Serotonin	1982
Laminar distribution of serotonergic innervation in rat somatosensory cortex, as determined by in vivo electrochemical detection. Brain research, 1983, Jan-17, Volume: 259, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Electrochemistry; Fenclonine; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Somatosensory Cortex	1983
The effects of amfonelic acid on 5-HT metabolism in rat brain. Journal of neural transmission, 1983, Volume: 57, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Nalidixic Acid; Naphthyridines; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1983
[Central serotonin metabolism in depression]. Nederlands tijdschrift voor geneeskunde, 1980, Jun-14, Volume: 124, Issue:24 Topics: 5-Hydroxytryptophan; Affect; Brain; Depression; Humans; Longitudinal Studies; Probenecid; Serotonin; Tryptophan	1980
Du 24565, a quipazine derivative, a potent selective serotonin uptake inhibitor. European journal of pharmacology, 1981, Mar-12, Volume: 70, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Blood Platelets; In Vitro Techniques; Male; Mice; p-Chloroamphetamine; Probenecid; Quinolines; Quipazine; Rabbits; Rats; Serotonin; Serotonin Antagonists; Synaptosomes; Tyramine	1981
Value of monoamine metabolite determinations in CSF as an index of their concentrations in rat brain following various pharmacological manipulations. Journal of pharmacological methods, 1982, Volume: 8, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Haloperidol; Indoles; Levodopa; Male; Probenecid; Rats; Rats, Inbred Strains; Time Factors	1982
Antagonistic actions of renal dopamine and 5-hydroxytryptamine: effects of amine precursors on the cell inward transfer and decarboxylation. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Tubules, Proximal; Levodopa; Male; Probenecid; Rats; Rats, Wistar; Renal Agents; Serotonin	1996