5-hydroxytryptophan has been researched along with naloxone in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (69.77) | 18.7374 |
| 1990's | 9 (20.93) | 18.2507 |
| 2000's | 4 (9.30) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hosoya, E; Oka, T | 1 |
| Paalzow, G; Paalzow, L | 1 |
| Oka, T | 1 |
| Bodner, RJ; Karpiak, SE; Tamir, H; Wajda, IJ; Wilchek, M | 1 |
| Chrétien, M; Motomatsu, T; Seidah, N | 1 |
| Adams, JE; Hosobuchi, Y; Li, CH; Meglio, M | 1 |
| Ahtee, L; Carlsson, A | 1 |
| Bertermann, RE; Dajani, EZ; Roge, EA; Schweingruber, FL; Woods, EM | 1 |
| Cancela, L; Molina, VA; Volosin, M | 1 |
| Becú-Villalobos, D; Lacau-Mengido, IM; Libertun, C | 1 |
| Constans, M; Reny-Palasse, V; Rips, R | 1 |
| Del Rio, J; Fernandez-Tome, MP; Gonzalez, Y | 1 |
| Carvey, P; Goetz, CG; Klawans, HL; Paulseth, JE | 1 |
| Emmers, R; Tamir, H; Wilchek, M | 1 |
| Ho, IK; Loh, HH; Way, EL | 1 |
| Pleuvry, BJ; Tobias, MA | 1 |
| Echols, SD; Jewett, RE | 1 |
| Collier, HO | 1 |
| Collier, HO; Francis, DL; Henderson, G; Schneider, C | 1 |
| Fujisaki, T; Fukuda, T; Koja, T; Shimizu, T | 1 |
| Andersson, S; Thoren, P; Yao, T | 1 |
| Cerrito, F; Preziosi, P; Vacca, M | 2 |
| Chen, HT; Ieiri, T; Meites, J | 1 |
| Buescher, HH; Ebnöther, AM; Gadient, F; Hauser, D; Hill, RC; Huegi, BS; Petcher, TJ; Rissi, E; Roemer, D | 1 |
| Emmers, R | 1 |
| Contreras, E; Muñoz, M; Quijada, L; Tamayo, L | 1 |
| Berge, OG; Hole, K | 1 |
| del Río, J; Garzón, J; Rubio, J | 1 |
| Shimizu, T | 1 |
| Imura, H; Katakami, H; Kato, Y; Matsushita, N; Shimatsu, A | 1 |
| Ghosh, S; Poddar, MK | 1 |
| Bastide, P; Coudert, P; Rubat, C; Tronche, P | 1 |
| Cavallero, D; Giordano, G; Giusti, M; Guido, R; Valenti, S | 1 |
| Banner, SE; Sanger, GJ | 1 |
| Driessen, B; Giertz, H; Reimann, W | 1 |
| Feigenbaum, JJ; Howard, SG | 1 |
| Albuisson, E; Coudert, P; Couquelet, J; Moreau, S; Rubat, C | 1 |
| Bois, F; Coudert, P; Couquelet, J; Moreau, S; Rubat, C | 1 |
| Bebot, M; Coudert, P; Couquelet, J; Courteix, C; Fialip, J; Rubat, C | 1 |
| Horikoshi, R; Kato, K; Niwa, SI; Shishido, T; Watanabe, Y | 1 |
| Esteban, S; García-Sevilla, JA; Sastre-Coll, A | 1 |
| Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO | 1 |
43 other study(ies) available for 5-hydroxytryptophan and naloxone
| Article | Year |
|---|---|
Effects of humoral modulators and naloxone on morphine-induced changes in the spontaneous locomotor activity of the rat.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Fenclonine; Levodopa; Male; Methyltyrosines; Morphine; Motor Activity; Naloxone; Neurotransmitter Agents; Rats; Scopolamine | 1976 |
Clonidine antinociceptive activity: effects of drugs influencing central monoaminergic and cholinergic mechanisms in the rat.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Atropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Chlorpromazine; Clonidine; Electroshock; Fenclonine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Naloxone; Parasympathetic Nervous System; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Reserpine; Sympathetic Nervous System; Vocalization, Animal; Yohimbine | 1976 |
Role of 5-hydroxytryptamine in morphine-, pethidine-, and methadone-induced hypothermia in rats at low ambient and room temperature.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Cold Temperature; Depression, Chemical; Drug Interactions; Fenclonine; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Temperature; Time Factors | 1977 |
Analgesic effects of N-acetyl-5HTP-5HTP amide are not directly related to brain serotonin levels.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Brain Chemistry; Male; Naloxone; Pain; Rats; Reaction Time; Receptors, Opioid; Serotonin; Time Factors | 1979 |
Cataleptic effect of 61-91 beta-lipotropic hormone in rat.
Topics: 5-Hydroxytryptophan; Animals; beta-Lipotropin; Catalepsy; Catatonia; Dose-Response Relationship, Drug; Humans; Levodopa; Naloxone; Rats; Sheep; Tremor | 1977 |
beta-Endorphin: development of tolerance and its reversal by 5-hydroxytryptophan in cats.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Cats; Drug Tolerance; Endorphins; Naloxone | 1977 |
Dual action of methadone on 5-HT synthesis and metabolism.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine | 1979 |
Naloxone reversal of drug-induced diarrhea in mice.
Topics: 5-Hydroxytryptophan; Animals; Antidiarrheals; Cyproheptadine; Diarrhea; Dose-Response Relationship, Drug; Male; Methacholine Compounds; Mice; Morphine; Naloxone; Propantheline; Prostaglandins F | 1979 |
Opioid involvement in the adaptive change of 5-HT1 receptors induced by chronic restraint.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; beta-Endorphin; Male; Methoxydimethyltryptamines; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Serotonin; Restraint, Physical; Stress, Psychological | 1990 |
Developmental changes in FSH secretion induced by 5-hydroxytryptophan, naloxone and haloperidol in male and female rats.
Topics: 5-Hydroxytryptophan; Aging; Animals; Female; Follicle Stimulating Hormone; Haloperidol; Male; Naloxone; Rats; Rats, Inbred Strains | 1989 |
Potentiation by TRH of the effect of antidepressants in the forced-swimming test, involvement of dopaminergic and opioid systems.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Dopamine; Drug Synergism; Male; Mice; Naloxone; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone | 1989 |
Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived rats.
Topics: 5-Hydroxytryptophan; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Feeding Behavior; Food Deprivation; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1988 |
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea Pigs; Haloperidol; Lisuride; Morphine; Myoclonus; Naloxone; Scopolamine; Tremorine | 1986 |
Influence of a serotonin receptor antagonist, 5-HTP-DP-hex, on spinal and thalamic nociceptive neurons in rats.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Ketanserin; Male; Methysergide; Naloxone; Nerve Fibers; Pain; Periaqueductal Gray; Rats; Reaction Time; Sciatic Nerve; Spinothalamic Tracts; Thalamic Nuclei | 1987 |
Brain 5-hydroxytryptamine and cyclic AMP in morphine tolerance and dependence.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Analgesics; Animals; Body Weight; Brain; Brain Chemistry; Cyclic AMP; Cycloheximide; Drug Tolerance; Fenclonine; Humans; Mice; Morphine; Morphine Dependence; Naloxone; Rats; Serotonin; Serotonin Antagonists; Time Factors; Tryptamines; Tryptophan; Tryptophan Hydroxylase | 1974 |
Comparison of the antinociceptive activities of physostigmine, oxotremorine and morphine in the mouse.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Brain Chemistry; Carbamates; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Combinations; Drug Synergism; Female; Fenclonine; Hot Temperature; Male; Methyltyrosines; Mice; Morphine; Nalorphine; Naloxone; Oxotremorine; Physostigmine; Reaction Time; Reserpine; Serotonin; Stimulation, Chemical; Tremorine | 1971 |
Effects of morphine on sleep in the cat.
Topics: 5-Hydroxytryptophan; Animals; Cats; Electroencephalography; Male; Methyltyrosines; Morphine; Naloxone; Sleep; Sleep Deprivation; Sleep, REM | 1972 |
The concept of the quasi-abstinence effect and its use in the investigation of dependence mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Hormones; Humans; Naloxone; Phosphodiesterase Inhibitors; Rats; Serotonin; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline | 1974 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; Drug Synergism; Heroin; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1974 |
Effects of methysergide and naloxone on analgesia induced by the peripheral electric stimulation in mice.
Topics: 5-Hydroxytryptophan; Animals; Brain; Electric Stimulation; Male; Methysergide; Mice; Naloxone; Nociceptors; Peripheral Nerves; Receptors, Opioid; Receptors, Serotonin; Serotonin | 1981 |
Long-lasting cardiovascular depressor response following sciatic stimulation in spontaneously hypertensive rats. Evidence for the involvement of central endorphin and serotonin systems.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brompheniramine; Dexamethasone; Electric Stimulation; Endorphins; Heart; Heart Rate; Hypertension; Naloxone; Neural Inhibition; Nociceptors; Rats; Rats, Inbred Strains; Sciatic Nerve; Serotonin; Synaptic Transmission; Zimeldine | 1982 |
Serotonergic and endogenous opiates interplay in the control of ACTH and prolactin release.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Bacitracin; Corticosterone; Endorphins; Naloxone; Prolactin; Rats; Serotonin | 1983 |
Naloxone stimulation of luteinizing hormone release in prepubertal female rats; role of serotonergic system.
Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Luteinizing Hormone; Morphine; Naloxone; Rats; Serotonin; Stimulation, Chemical | 1980 |
Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Membranes; Mice; Naloxone; Piperidines; Rats; Reaction Time; Serotonin Antagonists; Structure-Activity Relationship | 1983 |
Effects of naloxone on the secretion of prolactin and corticosterone induced by 5-hydroxytryptophan and a serotonergic agonist, mCPP.
Topics: 5-Hydroxytryptophan; Animals; Corticosterone; Fluoxetine; Male; Naloxone; Piperazines; Prolactin; Rats; Rats, Inbred Strains | 1983 |
Functional changes in the descending antinociceptive system of morphine-dependent rats.
Topics: 5-Hydroxytryptophan; Animals; Efferent Pathways; Electric Stimulation; Humans; Male; Morphine; Naloxone; Neurons; Nociceptors; Periaqueductal Gray; Raphe Nuclei; Rats; Sciatic Nerve; Substance-Related Disorders; Thalamic Nuclei | 1984 |
Decrease of tolerance and physical dependence on morphine by drugs affecting brain serotonin.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Fenfluramine; Humans; Mice; Morphine Dependence; Naloxone; Rats; Serotonin; Serotonin Antagonists; Tryptophan | 1980 |
Tolerance to the antinociceptive effect of morphine in the spinal rat.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Drug Tolerance; Humans; Male; Morphine; Naloxone; Rats; Serotonin; Spinal Cord; Substance Withdrawal Syndrome | 1981 |
Naloxone blocks the effect of 5-hydroxy-tryptophan on passive avoidance learning in rats: implication of endogenous opiod peptides.
Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Behavior, Animal; Clorgyline; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Serotonin | 1981 |
[Effects of peripheral electric stimulation on the central 5-hydroxytryptamine in mice: relation to the peripheral stimulation-produced analgesia (author's transl)].
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Brain Chemistry; Corticosterone; Electric Stimulation; Male; Methoxydimethyltryptamines; Methysergide; Mice; Morphine; Naloxone; Serotonin; Time Factors | 1981 |
Inhibition of naloxone of prolactin release induced by L-5-hydroxytryptophan in rats.
Topics: 5-Hydroxytryptophan; Animals; Drug Antagonism; Kinetics; Male; Naloxone; Prolactin; Rats; Rats, Inbred Strains | 1981 |
Higher environmental temperature-induced increase in body temperature: involvement of serotonin in GABA mediated interaction of opioidergic system.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Body Temperature; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hot Temperature; Hydroxyindoleacetic Acid; Male; Methysergide; Morphine; Naloxone; Physostigmine; Rats; Serotonin; Tryptophan | 1993 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine | 1995 |
Opioid tonus and luteinizing hormone secretion in anorexia nervosa: priming effect with serotonin precursor L-5-hydroxytryptophan during pulsatile gonadotropin-releasing hormone administration.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Anorexia Nervosa; Female; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Menstrual Cycle; Naloxone; Serotonin | 1994 |
Differences between 5-HT3 receptor antagonists in modulation of visceral hypersensitivity.
Topics: 5-Hydroxytryptophan; Animals; Colon; Colonic Diseases, Functional; Hypersensitivity; Male; Muscle, Smooth; Naloxone; Physical Stimulation; Pressure; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.
Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chinchilla; Cocaine; Dopamine; Female; In Vitro Techniques; Male; Morphine; Naloxone; Norepinephrine; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synaptosomes; Tramadol; Yohimbine | 1993 |
Naloxone reverses the inhibitory effect of gamma-hydroxybutyrate on central DA release in vivo in awake animals: a microdialysis study.
Topics: 5-Hydroxytryptophan; Animals; Dopamine; Dose-Response Relationship, Drug; Idazoxan; Male; Microdialysis; Naloxone; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 1996 |
Synthesis of peripherally acting analgesic 3-arylpiperazinyl-5-benzyl-pyridazines.
Topics: 5-Hydroxytryptophan; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Benzyl Compounds; Drug Synergism; Male; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Pyridazines; Structure-Activity Relationship; Trazodone | 1996 |
Spirobutenolides substituted by arylpiperazinyl-carbonyl moieties. Synthesis and antinociceptive properties.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzoquinones; Drug Synergism; Furans; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Reaction Time; Spiro Compounds; Yohimbine | 1998 |
Synthesis and analgesic effects of 5-[4-(arylpiperazin-1-yl)alkylamino]-4-benzyl-3-methyl-1,2-oxa zin-6-one s.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Benzoquinones; Binding, Competitive; Brain Chemistry; Drug Synergism; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Oxazines; Pain Measurement; Piperazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Yohimbine | 2000 |
Effects of dopamine, NMDA, opiate, and serotonin-related agents on acute methamphetamine-induced self-injurious behavior in mice.
Topics: 5-Hydroxytryptophan; Animals; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Motor Activity; N-Methylaspartate; Naloxone; Narcotic Antagonists; Narcotics; Receptors, N-Methyl-D-Aspartate; Self-Injurious Behavior; Serotonin Agents; Sulpiride | 2000 |
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoamines; Brain; Dihydroxyphenylalanine; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome | 2002 |
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles | 2007 |