5-hydroxytryptophan and melatonin

5-hydroxytryptophan has been researched along with melatonin in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-199066 (52.80)18.7374
1990's23 (18.40)18.2507
2000's14 (11.20)29.6817
2010's18 (14.40)24.3611
2020's4 (3.20)2.80

Authors

AuthorsStudies
Toru, M1
Brownstein, MJ1
Wainwright, SD1
Baker, PC; Buda, RE; Hoff, KM1
Abe, H; Hayaishi, O; Hirata, F; Imura, H; Iwasaki, Y; Kato, Y; Ohgo, S; Senoh, S; Tokuyama, T1
YoungLai, EV1
Dunlap, WP; Harston, CT; Hennig, CW1
Brisson, P; Collin, JP; Juillard, MT1
Cremer-Bartels, G; Hollwich, F; Kotulla, W1
Saavedra, JM1
Kawashima, K; Miller, RL; Spector, S; Wurzburger, RJ1
Kvetnoĭ, IM; Raĭkhlin, NT1
Chin, JR1
Attia, AM; Nonaka, KO; Reiter, RJ; Withyachumnarnkul, B1
Attia, AM; el-Sebae, AH; Mostafa, MH; Nonaka, KO; Reiter, RJ; Soliman, SA; Withyachumnarnkul, B1
King, TS; Reiter, RJ; Richardson, BA; Steger, RW; Steinlechner, S1
Attia, AM; el-Sebae, AH; Mostafa, MH; Nonaka, KO; Reiter, RJ; Soliman, SA1
Buzzell, GR; Menendez-Pelaez, A; Reiter, RJ; Rodriguez, C1
Blengio, M; Ferretti, C; Genazzani, E; Ghi, P1
Attia, AM; el-sebae, AK; Mostafa, MH; Reiter, RJ; Soliman, SA; Withyachumnarnkul, B1
McIntyre, IM; Oxenkrug, GF1
Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ1
den Boer, JA; Westenberg, HG1
Sandyk, R1
Besharse, JC; Cahill, GM1
Champney, TH; Craft, CM; Holtorf, AP; Reiter, RJ1
Bradbury, AJ; Giddins, RE; Smith, JA1
Kiriyama, T; Okatani, Y; Sagara, Y; Yamanaka, S1
Barker, D; Harrington, J; Pierce, ME; Takahashi, JS1
Oxenkrug, GF; Reuss, S1
Nowak, JZ; Zawilska, J1
Oaknin, S; Reiter, RJ; Troiani, ME; Vaughan, GM; Vaughan, MK1
Abou Samra, AB; Bertrand, J; Durand, A; Fèvre-Montange, M; Loras, B; Tourniaire, J1
Callebert, J; Finocchiaro, L; Jallon, JM; Launay, JM1
Mitsuma, T; Nogimori, T1
Cavallo, A; Meyer, WJ; Richards, GE; Waldrop, RD1
Jacobsen, FM; Rogers, S; Rosenthal, NE; Sack, DA; Wehr, TA1
Grady, RK; Klein, DC; Mefford, IN; Namboodiri, MA; Sugden, D1
Balemans, MG; Ebels, I; Mans, DR; van Benthem, J1
Balemans, MG; de Morée, A; Ebels, I; Mans, DR; van Benthem, J1
Herbert, DC; Reiter, RJ1
Champney, TH; Reiter, RJ; Richardson, BA; Webb, SM1
Kohsaka, M; Mori, A; Takeuchi, H1
De Martino, LJ; De Prospo, ND; Mc Guinness, ET; Safinski, RJ1
Benson, B; Reiter, RJ; Vaughan, GM; Vaughan, MK1
Lu, KH; Meites, J1
Bensinger, RE; Klein, DC; Lovenberg, W; Weller, JL1
Colombini, CE; Henn, SW; McCoy, EE2
Lazarus, L; Smythe, GA1
Hartley, R; Smith, JA1
Corrodi, H; Jonsson, G1
Collin, P; Meiniel, A1
Van der Hoeven, T; Woolley, DW1
Daly, JW; Witkop, B1
Balemans, MG; van de Veerdonk, FC1
Axelrod, J; Larin, F; Rosasco, K; Shein, HM; Wurtman, RJ1
Owman, C; Rüdeberg, C1
Benson, B; Norris, JT; Vaughan, MK1
Lanskiĭ, VP; Mashkovskiĭ, MD1
Campaigne, E; Dinner, A1
Björklund, A; Nobin, A; Stenevi, U1
Larin, F; Shein, HM; Wilson, S; Wurtman, RJ1
Kostellow, AB; Morrill, GA1
De Prospo, ND; Hurley, J1
Baker, PC; Clise, RL; Hoff, KM1
Fingerman, M; Rao, KR1
Frohman, CE; Hryhorczuk, LM; McIntyre, IM; Novak, EA; Oxenkrug, GF1
Barchas, JD; Mefford, IN1
Collin, JP; Juillard, MT; Voisin, P2
de Paul Lynch, V; Friedman, E; Yocca, FD1
Miura, R; Uemura, T; Yamamoto, A; Yamano, T1
Chan, A; Ebadi, M1
Balemans, M; Collin, JP; Juillard, MT; Van Benthem, J1
Frowein, A; Lapin, V1
Arendt, J; Marston, A; Wirz-Justice, A1
Hanew, K; Rennels, EG; Shiino, M1
Brammer, GL1
Buchanan, BA; Porter, JK; Stuedemann, JA; Thompson, FN; Tucker, HA1
Iuvone, PM; Thomas, KB; Tigges, M1
Míguez, JM; Pévet, P; Simonneaux, V1
Dubousset, J; Kimura, J; Machida, M; Miyashita, Y; Murai, I; Yamada, T1
Harumi, T; Matsushima, S1
Aldegunde, M; Míguez, JM; Recio, J; Sánchez-Barceló, E1
Brown, AD; Iuvone, PM; Thomas, KB1
Liburdy, R; Mori, A; Noda, Y; Packer, L1
Porter, JK; Rimando, AM1
Afeche, SC; Bartol, I; Canteras, NS; Cipolla-Neto, J; Mota, SR; Scialfa, JH; Skorupa, AL; Terra, IM1
Chaube, R; Joy, KP1
VANDERHOEVEN, T; WOOLLEY, DW1
Keithahn, C; Lerchl, A1
Esteban, S; Garmundi, A; Ibars, CB; Nicolaus, C; Ortega, E; Rial, RV; Rodríguez, AB1
Lutterschmidt, DI; Mason, RT1
Siopes, T; Steele, CT; Tosini, G; Underwood, H1
Alexiuk, NA; Vriend, J1
Bryla, J; Derlacz, RA; Drozak, J; Piekutowska, A; Sliwinska, M; Winiarska, K1
Allegri, G; Bertazzo, A; Comai, S; Costa, CV; Longatti, P; Perin, A; Rizzo, V1
Almeida, AC; Castilhos, LR; Medeiros, MA; Nonaka, KO; Olivares, El; Polo, PA; Reis, LC; Ribeiro, MC1
Afeche, SC; Barbosa, R; Cipolla-Neto, J; Scialfa, JH; Simonneaux, V; Terra, IM1
Chaturvedi, CM; Kumar, P; Mohan, J; Pati, AK; Sastry, KV; Tyagi, JS1
Chaturvedi, CM; Kumar, P1
Fuentes-Broto, L; García, JJ; López-Pingarrón, L; Martínez-Ballarín, E; Miana-Mena, FJ; Millán-Plano, S; Piedrafita, E; Sáenz, MA1
Arnulf, I; Boniol, C; Clot, F; Decaix, C; Leu-Semenescu, S; Levy, R; Moussa, F; Roze, E; Touitou, Y; Vidailhet, M1
Gupta, BB; Singh, KM; Yanthan, L1
Bruni, O; Novelli, L1
Back, K; Kim, YS; Lee, K; Park, S1
Costa, RC; Harasimowicz, J; Marques, KL; Prior, JA; Rodrigues, SS; Santos, JL; Silva, AF1
Brzozowska, I; Brzozowski, T; Drozdowicz, D; Hubalewska-Mazgaj, M; Laidler, PM; Stelmaszynska, T; Zagajewski, J1
Back, K; Byeon, Y; Kim, YS; Lee, HY; Park, S1
Brinkevich, SD; Shadyro, OI; Sverdlov, RL1
Lewczuk, B; Prusik, M; Przybylska-Gornowicz, B; Ziółkowska, N1
Adamska, I; Kedzierska, U; Majewski, PM; Piesiewicz, A; Turkowska, E1
Jagota, A; Reddy, MY1
Gdula-Argasińska, J; Kała, K; Muszyńska, B; Paśko, P; Sułkowska-Ziaja, K1
Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ1
Lewczuk, B; Prusik, M; Ziółkowska, N1
Cai, WJ; Feng, YQ; Wu, Y; Ye, T; Yin, X; Yu, L; Zheng, SJ1
Li, X; Ma, C; Wang, G; Yang, K; Zhao, F; Zhao, G1
Li, F; Li, X; Liu, G; Ma, C; Pan, J; Wang, C; Yang, K; Zhang, S; Zhang, W; Zhao, G1
Hanuszewska-Dominiak, M; Lewczuk, B; Martyniuk, K2
Du, YL; Li, H; Li, W; Shi, X; Wu, M; Zhao, G; Zhao, Z1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Reviews

6 review(s) available for 5-hydroxytryptophan and melatonin

ArticleYear
[Mechanisms of neurotransmission regulating circadian rhythms (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1978, Volume: 23, Issue:11

    Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Birds; Circadian Rhythm; Female; Hypothalamus; Melatonin; Norepinephrine; Pineal Gland; Rats; Sleep; Supraoptic Nucleus; Synaptic Transmission; Wakefulness

1978
[Melatonin in the retina of vertebrates].
    Acta physiologica Polonica, 1989, Volume: 40 Suppl 33

    Topics: 5-Hydroxytryptophan; Animals; Cattle; Chickens; Cricetinae; Hormones, Ectopic; Humans; Melatonin; Photoreceptor Cells; Rabbits; Rats; Retina

1989
The effect of neuropharmacological agents on metabolism of vitamin B 6 in brain.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Cannabis; Carbon Isotopes; Chromatography, Gel; Dihydroxyphenylalanine; Dopamine; Dronabinol; Ephedrine; Iproniazid; Liver; Melatonin; Mice; Norepinephrine; Phosphotransferases; Pyridoxal Phosphate; Pyridoxine; Rabbits; Reserpine; Semicarbazones; Serotonin

1972
The effect of neuropharmacological agents on metabolism in vitamin B6 in brain.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Cannabis; Carbon Isotopes; Chromatography, Gel; Dihydroxyphenylalanine; Dopamine; Dronabinol; Ephedrine; Iproniazid; Liver; Melatonin; Mice; Norepinephrine; Phosphotransferases; Pyridoxal Phosphate; Pyridoxine; Rabbits; Reserpine; Semicarbazones; Serotonin

1972
Sleep disorders in children.
    BMJ clinical evidence, 2010, Sep-27, Volume: 2010

    Topics: 5-Hydroxytryptophan; Child; Humans; Learning Disabilities; Melatonin; Parasomnias; Sleep; Sleep Wake Disorders

2010
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2018, 02-19, Volume: 2

    Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Benzodiazepines; Carisoprodol; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Fluoxetine; Humans; Magnesium; Malates; Melatonin; Monoamine Oxidase Inhibitors; Muscle Relaxants, Central; Pregabalin; Randomized Controlled Trials as Topic

2018

Trials

1 trial(s) available for 5-hydroxytryptophan and melatonin

ArticleYear
Neuroendocrine response to 5-hydroxytryptophan in seasonal affective disorder.
    Archives of general psychiatry, 1987, Volume: 44, Issue:12

    Topics: 5-Hydroxytryptophan; Adult; Blood Pressure; Depressive Disorder; Female; Growth Hormone; Humans; Hydrocortisone; Male; Melatonin; Placebos; Prolactin; Pulse; Seasons

1987

Other Studies

118 other study(ies) available for 5-hydroxytryptophan and melatonin

ArticleYear
The pineal gland.
    Life sciences, 1975, May-01, Volume: 16, Issue:9

    Topics: 5-Hydroxytryptophan; Acetyltransferases; Adrenergic beta-Antagonists; Animals; Bucladesine; Circadian Rhythm; Cyclic AMP; Enzyme Induction; Ganglia; Isoproterenol; Kinetics; Light; Melatonin; Norepinephrine; Pineal Gland; Rats; Receptors, Adrenergic; Serotonin

1975
Metabolism of tryptopan and serotonin by the chick pineal gland in organ culture.
    Canadian journal of biochemistry, 1977, Volume: 55, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Chickens; Light; Melatonin; Organ Culture Techniques; Pineal Gland; Serotonin; Time Factors; Tryptophan

1977
The effects of exogenous melatonin upon the gut of larval Xenopus laevis.
    General pharmacology, 1978, Volume: 9, Issue:6

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Carboxy-Lyases; Defecation; Digestive System; Digestive System Physiological Phenomena; Embryo, Nonmammalian; In Vitro Techniques; Larva; Melatonin; Monoamine Oxidase; Time Factors; Xenopus

1978
Effects of indoleamines and their newly identified metabolites on prolactin release in rats.
    Endocrinology, 1978, Volume: 103, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Male; Melatonin; Prolactin; Rats; Serotonin; Structure-Activity Relationship

1978
In vitro effects of melatonin on HCG stimulation of steroid accumulation by rabbit ovarian follicles.
    Journal of steroid biochemistry, 1979, Volume: 10, Issue:6

    Topics: 5-Hydroxytryptophan; Androstenedione; Animals; Chorionic Gonadotropin; Female; In Vitro Techniques; Melatonin; Ovarian Follicle; Progesterone; Rabbits; Serotonin; Testosterone

1979
Tonic immobility and skin color in anoles: effects of serotonin precursors and metabolites.
    Physiology & behavior, 1979, Volume: 22, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Hydroxyindoleacetic Acid; Immobilization; Lizards; Melatonin; Serotonin; Skin Pigmentation; Tryptophan

1979
[Synthesis of indolamines in the pineal organ of birds: radioautographic study in the parrot (Melopsittacus undulatus Shaw)].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1975, Jan-06, Volume: 280, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Cytoplasmic Granules; Golgi Apparatus; Indoleacetic Acids; Indoles; Melatonin; Nialamide; Parrots; Photoreceptor Cells; Pineal Gland; Protein Biosynthesis; Psittaciformes; Serotonin; Tritium

1975
[Melatonin biosynthesis in the mammalian retina in dependence of light adaptation (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1975, Volume: 167, Issue:1

    Topics: 5-Hydroxytryptophan; Adaptation, Ocular; Animals; Cattle; Dark Adaptation; Light; Melatonin; Retina; Retinal Pigments; Seasons; Serotonin; Tryptophan

1975
5-Hydroxy-L-tryptophan decarboxylase activity: microassay and distribution in discrete rat brain nuclei.
    Journal of neurochemistry, 1976, Volume: 26, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Brain; Brain Stem; Cerebral Ventricles; Dopa Decarboxylase; Hypothalamus; Male; Melatonin; Pargyline; Rats; Serotonin

1976
Determination of rat pineal gland melatonin content by a radioimmunoassay.
    Life sciences, 1976, Apr-15, Volume: 18, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Antibody Specificity; Antigens; Cross Reactions; Melatonin; Pargyline; Pineal Gland; Radioimmunoassay; Rats; Serotonin; Tryptophan

1976
[Biosynthesis of 5- methoxy-N-acetyltryptamine (melatonin) in enterochromaffin cells].
    Problemy endokrinologii, 1976, Volume: 22, Issue:2

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Chromaffin System; Chromatography, Thin Layer; Enterochromaffin Cells; Melatonin; Rabbits; Serotonin; Tryptamines

1976
Determination of six indolic compounds, including melatonin, in rat pineal using high-performance liquid chromatography with serial fluorimetric-electrochemical detection.
    Journal of chromatography, 1990, Jun-08, Volume: 528, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Spectrometry, Fluorescence; Tryptophan

1990
Changes in indole metabolism in organ cultured rat pineal glands induced by interferon-gamma.
    Journal of pineal research, 1990, Volume: 8, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Acetyltransferases; Analysis of Variance; Animals; Hydroxyindoleacetic Acid; Indoles; Interferon-gamma; Isoproterenol; Male; Melatonin; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Recombinant Proteins; Serotonin

1990
The organochlorine insecticide 1,2,3,4,5,6-hexachlorocyclohexane (lindane) but not 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) augments the nocturnal increase in pineal N-acetyltransferase activity and pineal and serum melatonin levels.
    Neurochemical research, 1990, Volume: 15, Issue:7

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; DDT; Hexachlorocyclohexane; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Serotonin

1990
Tryptophan administration inhibits nocturnal N-acetyltransferase activity and melatonin content in the rat pineal gland. Evidence that serotonin modulates melatonin production via a receptor-mediated mechanism.
    Neuroendocrinology, 1990, Volume: 52, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Hydroxyindoleacetic Acid; Kinetics; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1990
Carbaryl-induced changes in indoleamine synthesis in the pineal gland and its effects on nighttime serum melatonin concentrations.
    Toxicology, 1991, Volume: 65, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Body Temperature; Body Weight; Carbaryl; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Serotonin

1991
Indole and porphyrin content of the Syrian hamster harderian glands during the proestrous and estrous phases of the estrous cycle.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Cricetinae; Estrus; Female; Harderian Gland; Hydroxyindoleacetic Acid; Indoles; Melatonin; Mesocricetus; Porphyrins; Serotonin

1991
Differential effects of indolepyruvic acid and 5-hydroxytryptophan on indole metabolism in the pineal gland of the rat during the light-dark cycle.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Electrochemistry; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1990
Chronic administration of sublethal doses of carbaryl increases pineal N-acetyltransferase and hydroxyindole-O-methyltransferase activities and serum melatonin levels.
    Journal of pineal research, 1991, Volume: 10, Issue:1

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Administration, Oral; Animals; Arylamine N-Acetyltransferase; Carbaryl; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Serotonin; Statistics as Topic; Tryptophan

1991
Effect of ageing on melatonin synthesis induced by 5-hydroxytryptophan and constant light in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4

    Topics: 5-Hydroxytryptophan; Aging; Animals; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains

1991
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
    Brain research, 1991, Oct-11, Volume: 561, Issue:2

    Topics: 5-Hydroxytryptophan; Analysis of Variance; Butyrates; Butyric Acid; Cell Line; Colforsin; Dopamine; Eye Neoplasms; Humans; Kinetics; Levodopa; Melatonin; Retinoblastoma; Serotonin; Spiperone

1991
Behavioral, neuroendocrine, and biochemical effects of 5-hydroxytryptophan administration in panic disorder.
    Psychiatry research, 1990, Volume: 31, Issue:3

    Topics: 5-Hydroxytryptophan; Anxiety Disorders; Arousal; beta-Endorphin; Blood Platelets; Fear; Female; Humans; Hydrocortisone; Infusions, Intravenous; Male; Melatonin; Methoxyhydroxyphenylglycol; Panic; Personality Tests; Phobic Disorders; Receptors, Serotonin; Serotonin

1990
Pineal melatonin functions and the depression of Parkinson's disease: a hypothesis.
    The International journal of neuroscience, 1990, Volume: 51, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Depression; Dopamine; Humans; Melatonin; Models, Neurological; Parkinson Disease; Pineal Gland; Serotonin

1990
Circadian regulation of melatonin in the retina of Xenopus laevis: limitation by serotonin availability.
    Journal of neurochemistry, 1990, Volume: 54, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biological Availability; Circadian Rhythm; Culture Techniques; Dose-Response Relationship, Drug; Melatonin; Pargyline; Radioimmunoassay; Retina; Serotonin; Tryptophan Hydroxylase; Xenopus laevis

1990
Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections.
    Comparative biochemistry and physiology. A, Comparative physiology, 1986, Volume: 83, Issue:2

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Cricetinae; Diabetes Mellitus, Experimental; Hydroxyindoleacetic Acid; Insulin; Kinetics; Male; Melatonin; Mesocricetus; Pineal Gland; Rats; Serotonin; Species Specificity; Tryptophan

1986
Inhibition of serum melatonin concentration and synthesis of brain indolealkylamines by monofluoromethyldopa in the rat.
    Journal of pineal research, 1985, Volume: 2, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Cerebral Cortex; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Male; Melatonin; Methyldopa; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin

1985
Determination of plasma 5-hydroxytryptophan, 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, tryptophan and melatonin by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1988, Sep-23, Volume: 431, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Chromatography, High Pressure Liquid; Circadian Rhythm; Electrochemistry; Female; Haloperidol; Humans; Hydroxyindoleacetic Acid; Melatonin; Menstrual Cycle; Muscle, Smooth, Vascular; Serotonin; Tryptophan; Umbilical Arteries; Umbilical Veins

1988
Cyclic AMP-dependent melatonin production in Y79 human retinoblastoma cells.
    Journal of neurochemistry, 1989, Volume: 53, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 5-Hydroxytryptophan; 8-Bromo Cyclic Adenosine Monophosphate; Colforsin; Cyclic AMP; Humans; Melatonin; Middle Aged; Retinoblastoma; Tumor Cells, Cultured

1989
Chemical sympathectomy and clorgyline-induced stimulation of rat pineal melatonin synthesis.
    Journal of neural transmission, 1989, Volume: 78, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Clorgyline; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Sympathectomy, Chemical

1989
Injections of alpha-melanocyte stimulating hormone affect pineal serotonin, melatonin and N-acetyltransferase activity.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:1

    Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Cricetinae; Injections; Male; Melanocyte-Stimulating Hormones; Melatonin; Mesocricetus; Pineal Gland; Prolactin; Serotonin

1987
Effect of indolamines on beta-endorphin release by rat anterior pituitary cells.
    Neuroendocrinology, 1985, Volume: 41, Issue:6

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Creatinine; Drug Combinations; Endorphins; Hydroxytryptophol; In Vitro Techniques; Indoles; Male; Melatonin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
Melatonin biosynthesis in Drosophila: its nature and its effects.
    Journal of neurochemistry, 1988, Volume: 50, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, Thin Layer; Drosophila; Drosophila melanogaster; Female; Indoles; Male; Mass Spectrometry; Melatonin; Oviposition; Radioimmunoassay; Serotonin; Sexual Behavior, Animal

1988
Effects of various drugs on thyrotropin secretion in rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Endorphins; Fenclonine; Haloperidol; Hypothalamus; Levodopa; Male; Melatonin; Phenytoin; Protein Precursors; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors

1985
Evaluation of 5-hydroxytryptophan administration as a test of pineal function in humans.
    Hormone research, 1987, Volume: 27, Issue:2

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Child; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Time Factors

1987
Ovine pineal indoles: effects of L-tryptophan or L-5-hydroxytryptophan administration.
    Journal of neurochemistry, 1985, Volume: 44, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Male; Melatonin; Pineal Gland; Serotonin; Sheep; Time Factors; Tryptophan

1985
Rhythmic synthesis of various 5-methoxyindoles in the pineal gland of male adult golden hamsters, kept under the same artificial conditions throughout the year.
    Journal of neural transmission, 1985, Volume: 61, Issue:3-4

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Pineal Gland; Seasons; Tryptophan

1985
The effect of reduced neopterin on the synthesis of several methylated indoles in the pineal gland of adult male golden hamsters, kept under standardized conditions.
    Journal of neural transmission, 1985, Volume: 62, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Biopterins; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Methylation; Neopterin; Pineal Gland; Pteridines; Tryptophan

1985
Changes in pineal indoleamine metabolism in vitamin A deficient rats.
    Life sciences, 1985, Dec-30, Volume: 37, Issue:26

    Topics: 5-Hydroxytryptophan; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Indoles; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Vitamin A Deficiency

1985
Hormonal modulation of cyclic melatonin production in the pineal gland of rats and Syrian hamsters: effects of thyroidectomy or thyroxine implant.
    Chronobiology international, 1985, Volume: 2, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Cricetinae; Drug Implants; Male; Melatonin; Mesocricetus; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Thyroidectomy; Thyroxine; Tryptophan

1985
[Effect of indolamines and their analogs on the electric activity of on identified giant neuron of Achatina fulica Ferussac].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:4-5

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Action Potentials; Animals; Cyproheptadine; Melatonin; Methysergide; Neurons; Serotonin; Structure-Activity Relationship; Tryptamines; Tryptophan

1974
Melatonin and its precursors' effects on 131-I uptake by the thyroid gland under different photic conditions.
    Life sciences, 1969, Aug-01, Volume: 8, Issue:15

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Corticosterone; Darkness; Female; Iodine Isotopes; Light; Melatonin; Organ Size; Pituitary Gland; Rats; Serotonin; Thyroid Gland

1969
Effect of melatonin and other pineal indoles on adrenal enlargement produced in male and female mice by pinealectomy, unilateral adrenalectomy, castration, and cold stress.
    Neuroendocrinology, 1972, Volume: 10, Issue:3

    Topics: 5-Hydroxytryptophan; Acetates; Adrenal Glands; Adrenalectomy; Alcohols; Animals; Castration; Cold Temperature; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mice; Organ Size; Ovary; Pineal Gland; Serotonin; Testis

1972
Effects of serotonin precursors and melatonin on serum prolactin release in rats.
    Endocrinology, 1973, Volume: 93, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Female; Hypophysectomy; Melatonin; Pituitary Gland; Prolactin; Rats; Serotonin; Time Factors; Transplantation, Homologous; Tryptophan

1973
Radiometric assay of total tryptophan hydroxylation by intact cultured pineal glands.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Cycloheximide; Evaluation Studies as Topic; Female; Isoproterenol; Kinetics; Male; Melatonin; Mescaline; Methods; Mixed Function Oxygenases; Organ Culture Techniques; Phenylalanine; Pineal Gland; Probenecid; Rats; Serotonin; Species Specificity; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase

1974
Growth hormone regulation by melatonin and serotonin.
    Nature, 1973, Jul-27, Volume: 244, Issue:5413

    Topics: 5-Hydroxytryptophan; Animals; Binding, Competitive; Cyproheptadine; Depression, Chemical; Female; Growth Hormone; Male; Melatonin; Pineal Gland; Radioimmunoassay; Rats; Serotonin; Stimulation, Chemical

1973
Inhibition of catecholamine oxidation by indoles.
    Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15

    Topics: 5-Hydroxytryptophan; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopamine Antagonists; Fluorine; Fungi; Indoles; Kinetics; Melatonin; Monophenol Monooxygenase; Oxidation-Reduction; Serotonin; Spectrophotometry; Tryptamines; Tryptophan

1972
[Fluorescence methods on histochemical visualization of monoamines. 5. Identification of fluorescent product from model experiments with 5-methoxytryptamine and formaldehyde].
    Acta histochemica, 1965, Dec-24, Volume: 22, Issue:5

    Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Chemistry, Organic; Chromatography, Paper; Chromatography, Thin Layer; Fluorescence; Fluorometry; Formaldehyde; Histocytochemistry; Melatonin; Microscopy, Fluorescence; Organic Chemistry Phenomena; Spectrophotometry; Tryptamines

1965
[Monoamines of the pineal organ during the intra-uterine stages of development of an amniote. Studies in Lacerta vivipara (Jacquin), Reptile, Lacertilian].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1970, Dec-21, Volume: 271, Issue:25

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Embryo, Nonmammalian; Female; Fluorescence; Male; Melatonin; Pineal Gland; Reptiles; Reserpine; Tryptamines

1970
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
    International journal of neuropsychiatry, 1965, Volume: 1, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vitro Techniques; Intellectual Disability; Learning; Male; Melatonin; Mice; Neurosecretion; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Reserpine; Serotonin; Tryptamines; Tyrosine; Urine

1965
Selective exchange of nuclear protons in hydroxyindoles.
    Journal of the American Chemical Society, 1967, Feb-15, Volume: 89, Issue:4

    Topics: 5-Hydroxytryptophan; Deuterium; Hallucinogens; Indoles; Melatonin; Protons; Radiochemistry; Serotonin; Tritium; Tryptamines

1967
Fluorescence of indole derivatives.
    Experientia, 1967, Nov-15, Volume: 23, Issue:11

    Topics: 5-Hydroxytryptophan; Fluorescence; Fluorometry; Indoleacetic Acids; Indoles; Melatonin; Serotonin; Spectrum Analysis; Tryptamines; Tryptophan

1967
Formation of melatonin and 5-hydroxyindole acetic acid from 14C-tryptophan by rat pineal glands in organ culture.
    Nature, 1968, Mar-09, Volume: 217, Issue:5132

    Topics: 5-Hydroxytryptophan; Animals; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Female; Hydroxyindoleacetic Acid; Melatonin; Pineal Gland; Rats; Serotonin; Tryptophan

1968
Light, fluorescence, and electron microscopic studies on the pineal organ of the pike, Esox lucius L., with special regard to 5-hydroxytryptamine.
    Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1970, Volume: 107, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Endoplasmic Reticulum; Fishes; Fluorometry; Golgi Apparatus; Melatonin; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Nerve Fibers, Myelinated; Pineal Gland; Protein Biosynthesis; Reserpine; Ribosomes; Sensory Receptor Cells; Serotonin

1970
Inhibition of compensatory ovarian hypertrophy in mice by 5-hydroxytryptamine and melatonin.
    The Journal of endocrinology, 1970, Volume: 47, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Castration; Female; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injections, Subcutaneous; Melatonin; Mice; Organ Size; Ovary; Serotonin

1970
[The effect of precursors and various analogs of serotonin on the cerebral circulation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1968, Volume: 66, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Blood Flow Velocity; Blood Pressure; Cats; Cerebrovascular Circulation; Melatonin; Oxygen; Tryptamines; Vascular Resistance

1968
Benzo(b)thiophene derivatives. XVI. The sulfur isosteres of melatonin, bufotenine, 5-hydroxytryptophan, and related structures.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Chemical Phenomena; Chemistry; Hallucinogens; Melatonin; Mice; Rats; Thiophenes

1970
Acid catalysis of the formaldehyde condensation reaction for a sensitive histochemical demonstration of tryptamines and 3-methoxylated phenylethylamines. 2. Characterization of amine fluorophores and application to tissues.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1971, Volume: 19, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Dopamine; Epinephrine; Female; Fluorescence; Formaldehyde; Freeze Drying; Histamine; Histocytochemistry; Hydrochloric Acid; Male; Melatonin; Mescaline; Methods; Microscopy, Fluorescence; Norepinephrine; Normetanephrine; Pancreas; Phenethylamines; Rats; Serotonin; Spectrophotometry; Submandibular Gland; Tryptamines; Tryptophan; Tyramine; Tyrosine

1971
Stimulation of(14C)serotonin synthesis from (14C)tryptophan by mescaline in rat pineal organ cultures.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Mar-08, Volume: 10, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Carbon Isotopes; Deamination; Female; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Melatonin; Mescaline; Organ Culture Techniques; Pineal Gland; Protein Biosynthesis; Proteins; Psilocybin; Rats; Serotonin; Tryptophan

1971
Tryptophan induction of the serotonin and kynurenine pathways in the early amphibian embryo.
    Nature: New biology, 1971, May-26, Volume: 231, Issue:21

    Topics: 5-Hydroxytryptophan; Animals; Anura; Carbon Isotopes; Chloramphenicol; Chlorpromazine; Chromatography, Thin Layer; Culture Techniques; Depression, Chemical; Embryo, Nonmammalian; Enzyme Induction; Ethanol; Indoles; Iproniazid; Kynurenine; Melatonin; Mixed Function Oxygenases; Protein Biosynthesis; RNA; Serotonin; Tryptophan; Tryptophan Oxygenase

1971
A comparison of intracerebral and intraperitoneal injections of melatonin and its precursors on 131 I uptake by the thyroid glands of rats.
    Agents and actions, 1971, Volume: 2, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Body Weight; Depression, Chemical; Female; Injections; Injections, Intraperitoneal; Iodine; Iodine Isotopes; Melatonin; Organ Size; Oxygen Consumption; Pituitary Gland; Rats; Rats, Inbred Strains; Serotonin; Thyroid Gland; Time Factors

1971
The effects of light and dark backgrounds upon indoleamine enzymes in developing Xenopus laevis.
    Comparative and general pharmacology, 1971, Volume: 2, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carboxy-Lyases; Darkness; Embryo, Nonmammalian; Enzymes; Eye; Hydroxyindoleacetic Acid; Indoles; Larva; Light; Melatonin; Metamorphosis, Biological; Methyltransferases; Monoamine Oxidase; Serotonin; Xenopus

1971
Action of biogenic amines on crustacean chromatophores. II. Analysis of the responses of erythrophores in the fiddler crab, Uca pugilator, to indolealkylamines and an eyestalk hormone.
    Comparative and general pharmacology, 1970, Volume: 1, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brachyura; Central Nervous System; Chromatophores; Creatinine; Dose-Response Relationship, Drug; Eye; Hallucinogens; Hormones; In Vitro Techniques; Lysergic Acid Diethylamide; Melatonin; Perfusion; Serotonin; Time Factors; Tissue Extracts; Tryptamines

1970
Differential effect of carbidopa on the concentration of rat pineal and hypothalamic indoleamines.
    Journal of pineal research, 1984, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Hydroxyindoleacetic Acid; Hypothalamus; Male; Melatonin; Organ Specificity; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin

1984
Determination of tryptophan and metabolites in rat brain and pineal tissue by reversed-phase high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1980, Feb-08, Volume: 181, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Serotonin; Tryptophan

1980
Indole metabolism in the pineal organ of the pigeon with special reference to melatonin-synthesizing cells. In vitro study combining thin layer chromatography, autoradiography and pharmacological treatment.
    Cell and tissue research, 1983, Volume: 230, Issue:1

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5-Hydroxytryptophan; Animals; Autoradiography; Chromatography, Thin Layer; Columbidae; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mitochondria; Nialamide; Pineal Gland; Serotonin; Theophylline

1983
Effect of chronic lithium treatment on rat pineal rhythms: N-acetyltransferase, N-acetylserotonin and melatonin.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3

    Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Body Weight; Circadian Rhythm; Cyclic AMP; Hydroxyindoleacetic Acid; Isoproterenol; Lithium; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1983
Microsomal methoxymelanin formation from 6-hydroxymelatonin.
    FEBS letters, 1980, Dec-29, Volume: 122, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Electron Spin Resonance Spectroscopy; Male; Melanins; Melatonin; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxygen Consumption; Rats; Superoxides

1980
Reciprocal relationship between the concentrations of serotonin and the activity of serotonin-N-acetyltransferase in rat pineal glands in culture.
    Endocrine research communications, 1981, Volume: 8, Issue:1

    Topics: 5-Hydroxytryptophan; Acetyl Coenzyme A; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Benserazide; Cyclic AMP; Fenclonine; Melatonin; Norepinephrine; Organ Culture Techniques; Pineal Gland; Propranolol; Rats; Serotonin; Theophylline; Trypsin

1981
[Retention of indoles in the pineal organ of the bird (Melopsittacus undulatus, Shaw) during its preparation for radioautographic study].
    Biology of the cell, 1983, Volume: 49, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Female; Fixatives; Glutaral; Indoles; Male; Melatonin; Microscopy, Electron; Parakeets; Pineal Gland; Psittaciformes; Serotonin; Tritium

1983
Effects of growing tumours on pineal melatonin levels in male rats.
    Journal of neural transmission, 1981, Volume: 52, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Cell Division; Fenclonine; Kinetics; Male; Melatonin; Nialamide; Pineal Gland; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Serotonin

1981
Antidepressant drugs elevate rat pineal and plasma melatonin.
    Experientia, 1980, Apr-15, Volume: 36, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Melatonin; Pineal Gland; Rats

1980
Effect of indoles, AVT, oxytocin, and AVP on prolactin secretion in rat pituitary clonal (2B8) cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 164, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Arginine Vasopressin; Cells, Cultured; Dose-Response Relationship, Drug; Indoles; Melatonin; Oxytocin; Pituitary Gland; Prolactin; Rats; Serotonin

1980
[Radioautographic study of "in vitro" incorporation of [3H]-hydroxyindoles and [3H]-melatonin into the pineal organ of the pigeon].
    Archives d'anatomie microscopique et de morphologie experimentale, 1982, Volume: 71, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Cell Line; Columbidae; Melatonin; Microscopy, Electron; Photoreceptor Cells; Pineal Gland; Serotonin

1982
Duodenum is not a consistent source of melatonin in rats.
    Life sciences, 1994, Volume: 55, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Chromatography; Duodenum; In Vitro Techniques; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Spectrometry, Fluorescence; Tryptophan

1994
Melatonin and pineal neurochemicals in steers grazed on endophyte-infected tall fescue: effects of metoclopramide.
    Journal of animal science, 1993, Volume: 71, Issue:6

    Topics: 5-Hydroxytryptophan; Acremonium; Animal Feed; Animals; Cattle; Dopamine; Fertilizers; Food Microbiology; Male; Melatonin; Metoclopramide; Nitrogen; Norepinephrine; Pineal Gland; Poaceae; Random Allocation; Serotonin

1993
Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid.
    Brain research, 1993, Jan-22, Volume: 601, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Chickens; Circadian Rhythm; Dopamine; In Vitro Techniques; Kainic Acid; Male; Melatonin; Neurons; Retina; Serotonin; Tryptophan; Tryptophan Hydroxylase

1993
Changes in pineal indoleamines in rats after single melatonin injections: evidence for a diurnal sensitivity to melatonin.
    Journal of neuroendocrinology, 1996, Volume: 8, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin

1996
Role of serotonin for scoliotic deformity in pinealectomized chicken.
    Spine, 1997, Jun-15, Volume: 22, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Chickens; Male; Melatonin; Pineal Gland; Posture; Radiography; Reflex; Scoliosis; Serotonin; Spine

1997
Indoleamine metabolism in the pineal gland of the Chinese hamster, Cricetulus griseus.
    General and comparative endocrinology, 1998, Volume: 109, Issue:1

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Biogenic Monoamines; Circadian Rhythm; Cricetinae; Cricetulus; Dopamine; Male; Melatonin; Pineal Gland; Serotonin; Tritium; Tryptamines; Tryptophan

1998
Changes with age in daytime and nighttime contents of melatonin, indoleamines, and catecholamines in the pineal gland: a comparative study in rat and Syrian hamster.
    Journal of pineal research, 1998, Volume: 25, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Catecholamines; Circadian Rhythm; Cricetinae; Dopamine; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mesocricetus; Norepinephrine; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin

1998
Elevation of melatonin in chicken retina by 5-hydroxytryptophan: differential light/dark responses.
    Neuroreport, 1998, Dec-21, Volume: 9, Issue:18

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Administration, Topical; Animals; Arylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Dose-Response Relationship, Drug; Eye; Light; Melatonin; Photoperiod; Retina

1998
Melatonin and its precursors scavenge nitric oxide.
    Journal of pineal research, 1999, Volume: 27, Issue:3

    Topics: 5-Hydroxytryptophan; Cadmium; Copper; Free Radical Scavengers; Hydrazines; Indicators and Reagents; Kinetics; Melatonin; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Serotonin; Tryptophan

1999
Effects of Fusarium mycotoxins on levels of serotonin, melatonin, and 5-hydroxytryptophan in pineal cell cultures.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Carboxylic Acids; Cells, Cultured; Fumonisins; Fusaric Acid; Fusarium; Melatonin; Mycotoxins; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Trichothecenes

1999
Lesions of the dorsomedial hypothalamic nucleus do not influence the daily profile of pineal metabolism in rats.
    Neuroendocrinology, 2001, Volume: 73, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Dorsomedial Hypothalamic Nucleus; Electrosurgery; Hydroxyindoleacetic Acid; Hypothalamus; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Serotonin; Tryptophan

2001
Effects of altered photoperiod and temperature, serotonin-affecting drugs, and melatonin on brain tyrosine hydroxylase activity in female catfish, Heteropneustes fossilis: a study correlating ovarian activity changes.
    The Journal of experimental zoology, 2002, Nov-01, Volume: 293, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Brain; Catfishes; Female; Fenclonine; Melatonin; Ovary; Photoperiod; Reproduction; Serotonin Agents; Temperature; Tyrosine 3-Monooxygenase

2002
PREVENTION OF A MENTAL DEFECT OF PHENYLKETONURIA WITH SEROTONIN CONGENERS SUCH AS MELATONIN OR HYDROXYTRYPTOPHAN.
    Science (New York, N.Y.), 1964, Jun-26, Volume: 144, Issue:3626

    Topics: 5-Hydroxytryptophan; Animals; Biomedical Research; Indoles; Learning; Melatonin; Mice; Pharmacology; Phenylalanine; Phenylketonurias; Research; Serotonin; Tyrosine

1964
5-hydroxytryptophan is a more potent in vitro hydroxyl radical scavenger than melatonin or vitamin C.
    Journal of pineal research, 2005, Volume: 38, Issue:1

    Topics: 5-Hydroxytryptophan; Ascorbic Acid; Dose-Response Relationship, Drug; Free Radical Scavengers; Luminescence; Melatonin

2005
Effect of orally administered L-tryptophan on serotonin, melatonin, and the innate immune response in the rat.
    Molecular and cellular biochemistry, 2004, Volume: 267, Issue:1-2

    Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Circadian Rhythm; Diencephalon; Drug Administration Schedule; Hydroxyindoleacetic Acid; Macrophages, Peritoneal; Male; Melatonin; Phagocytosis; Radioimmunoassay; Rats; Rats, Wistar; Serotonin; Time Factors; Tryptophan; Tryptophan Hydroxylase

2004
A serotonin receptor antagonist, but not melatonin, modulates hormonal responses to capture stress in two populations of garter snakes (Thamnophis sirtalis parietalis and Thamnophis sirtalis concinnus).
    General and comparative endocrinology, 2005, May-01, Volume: 141, Issue:3

    Topics: 5-Hydroxytryptophan; Adjuvants, Immunologic; Androgens; Animals; Colubridae; Corticosterone; Endocrine System; Ketanserin; Melatonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Stress, Physiological

2005
Time keeping by the quail's eye: circadian regulation of melatonin production.
    General and comparative endocrinology, 2006, Volume: 145, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Biological Clocks; Circadian Rhythm; Coturnix; Darkness; Eye; Light; Male; Melatonin; Retina; Serotonin; Time Factors; Tissue Culture Techniques

2006
Melatonin: effects on dopaminergic and serotonergic neurons of the caudate nucleus of the striatum of male Syrian hamsters.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Circadian Rhythm; Cricetinae; Dopamine; Enzyme Inhibitors; Levodopa; Male; Melatonin; Mesocricetus; Neural Pathways; Neurons; Serotonin; Sex Factors; Synaptic Transmission; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

2007
Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury.
    Journal of pineal research, 2007, Volume: 42, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Hyperglycemia; Kidney Cortex; Kidney Diseases; Kidney Tubules; Male; Melatonin; Organ Culture Techniques; Rabbits; Taurine

2007
A study of tryptophan metabolism via serotonin in ventricular cerebrospinal fluid in HIV-1 infection using a neuroendoscopic technique.
    Current HIV research, 2007, Volume: 5, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aged; Cerebral Ventricles; Endoscopy; HIV Infections; HIV-1; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Male; Melatonin; Serotonin; Tryptophan; Ventriculostomy

2007
Nocturnal plasma levels of melatonin in quails (Coturnix japonica) injected with l-5-hydroxy-tryptophan.
    Brazilian journal of biology = Revista brasleira de biologia, 2007, Volume: 67, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Coturnix; Melatonin; Pineal Gland; Radioimmunoassay

2007
Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland.
    Life sciences, 2008, Feb-27, Volume: 82, Issue:9-10

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Arylalkylamine N-Acetyltransferase; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chromatography, High Pressure Liquid; Cyclic CMP; Dose-Response Relationship, Drug; Electrochemistry; In Vitro Techniques; Isoproterenol; Melatonin; Nifedipine; Norepinephrine; Pineal Gland; Rats; Rats, Wistar; Serotonin; Tryptophan Hydroxylase

2008
Effects of simulated hypo- and hyper-reproductive conditions on the characteristics of circadian rhythm in hypothalamic concentration of serotonin and dopamine and in plasma levels of thyroxine, triiodothyronine, and testosterone in Japanese quail, Coturn
    Chronobiology international, 2009, Volume: 26, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Coturnix; Dopamine; Hypothalamus; Levodopa; Male; Melatonin; Pineal Gland; Reproduction; Serotonin; Testosterone; Thyroxine; Triiodothyronine

2009
Reproductive responses and nitric oxide activity in Japanese quail, Coturnix coturnix japonica, are altered by specific phase relationships of neural (serotonergic and dopaminergic) oscillations and pineal function.
    Domestic animal endocrinology, 2009, Volume: 36, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Biological Clocks; Cloaca; Coturnix; Dopamine; Levodopa; Male; Melatonin; Neurons; Nitrates; Nitric Oxide; Nitrites; Organ Size; Pineal Gland; Random Allocation; Serotonin; Spermatogenesis; Testosterone

2009
Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.
    International journal of molecular sciences, 2010, Jan-21, Volume: 11, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Antioxidants; Carbolines; Free Radicals; Intracellular Membranes; Kinetics; Male; Melatonin; Neuroprotective Agents; Oxidation-Reduction; Rats; Synaptosomes; Tryptophan

2010
Sleep and rhythm consequences of a genetically induced loss of serotonin.
    Sleep, 2010, Volume: 33, Issue:3

    Topics: 5-Hydroxytryptophan; Adult; Alcohol Oxidoreductases; Antidepressive Agents, Second-Generation; Consanguinity; Disorders of Excessive Somnolence; Dopamine; Dopamine Agents; Drug Therapy, Combination; Humans; Hydrocortisone; Hyperphagia; Levodopa; Male; Melatonin; Polysomnography; Serotonin; Sleep; Sleep Disorders, Circadian Rhythm

2010
In vitro effects of 5-hydroxytryptophan, indoleamines and leptin on arylalkylamine N-acetyltransferase (AA-NAT) activity in pineal organ of the fish, Clarias gariepinus (Burchell, 1822) during different phases of the breeding cycle.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Second-Generation; Antioxidants; Arylalkylamine N-Acetyltransferase; Breeding; Catfishes; Leptin; Melatonin; Pineal Gland; Radioimmunoassay; Serotonin; Serotonin Receptor Agonists

2010
Tryptamine 5-hydroxylase-deficient Sekiguchi rice induces synthesis of 5-hydroxytryptophan and N-acetyltryptamine but decreases melatonin biosynthesis during senescence process of detached leaves.
    Journal of pineal research, 2012, Volume: 52, Issue:2

    Topics: 5-Hydroxytryptophan; Cellular Senescence; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Melatonin; Oryza; Plant Leaves; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; Tryptamines

2012
Chemiluminometric evaluation of melatonin and selected melatonin precursors' interaction with reactive oxygen and nitrogen species.
    Analytical biochemistry, 2012, Jan-01, Volume: 420, Issue:1

    Topics: 5-Hydroxytryptophan; Automation, Laboratory; Chemistry Techniques, Analytical; Equipment Design; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Luminescence; Luminol; Melatonin; Peroxynitrous Acid; Reactive Oxygen Species; Tryptophan

2012
Conversion L-tryptophan to melatonin in the gastrointestinal tract: the new high performance liquid chromatography method enabling simultaneous determination of six metabolites of L-tryptophan by native fluorescence and UV-VIS detection.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:6

    Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Female; Gastrointestinal Tract; Indoleacetic Acids; Kynurenine; Male; Melatonin; Rats; Rats, Wistar; Serotonin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan

2012
Relaxation drinks: an anti-frazzle fizzle?
    Consumer reports, 2013, Volume: 78, Issue:5

    Topics: 5-Hydroxytryptophan; Beverages; Consumer Product Safety; gamma-Aminobutyric Acid; Humans; Melatonin; Plant Preparations; Product Labeling; Relaxation; Sleep Stages; Tea

2013
Elevated production of melatonin in transgenic rice seeds expressing rice tryptophan decarboxylase.
    Journal of pineal research, 2014, Volume: 56, Issue:3

    Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Melatonin; Oryza; Plants, Genetically Modified; Seeds; Serotonin; Tryptamines

2014
Interaction of tryptophan and related compounds with oxygen- and carbon-centered radicals.
    Free radical research, 2014, Volume: 48, Issue:10

    Topics: 5-Hydroxytryptophan; Antioxidants; Carbon; Free Radicals; Melatonin; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Serotonin; Tryptophan

2014
Diurnal profiles of melatonin synthesis-related indoles, catecholamines and their metabolites in the duck pineal organ.
    International journal of molecular sciences, 2014, Jul-16, Volume: 15, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Ducks; Indoles; Melatonin; Pineal Gland; Serotonin

2014
Seasonal postembryonic maturation of the diurnal rhythm of serotonin in the chicken pineal gland.
    Chronobiology international, 2015, Volume: 32, Issue:1

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Age Factors; Animals; Aromatic-L-Amino-Acid Decarboxylases; Arylalkylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Female; Gene Expression Regulation, Enzymologic; Male; Melatonin; Photoperiod; Pineal Gland; RNA, Messenger; Seasons; Serotonin; Sex Factors; Time Factors; Tryptophan Hydroxylase

2015
Melatonin has differential effects on age-induced stoichiometric changes in daily chronomics of serotonin metabolism in SCN of male Wistar rats.
    Biogerontology, 2015, Volume: 16, Issue:3

    Topics: 5-Hydroxytryptophan; Aging; Animals; Chronobiology Phenomena; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Melatonin; Models, Animal; Rats; Rats, Wistar; Serotonin; Suprachiasmatic Nucleus

2015
Anti-inflammatory activities of garlic sprouts, a source of α-linolenic acid and 5-hydroxy-l-tryptophan, in RAW 264.7 cells.
    Acta biochimica Polonica, 2017, Volume: 64, Issue:3

    Topics: 5-Hydroxytryptophan; alpha-Linolenic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Darkness; Fatty Acids; Garlic; Glutathione Transferase; Indoles; Lipopolysaccharides; Melatonin; Mice; NF-kappa B; Plant Extracts; RAW 264.7 Cells

2017
Diurnal and circadian variations in indole contents in the goose pineal gland.
    Chronobiology international, 2018, Volume: 35, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Chickens; Circadian Rhythm; Darkness; Female; Geese; Indoles; Male; Melatonin; Photoperiod; Pineal Gland

2018
Metabolic analysis of the melatonin biosynthesis pathway using chemical labeling coupled with liquid chromatography-mass spectrometry.
    Journal of pineal research, 2019, Volume: 66, Issue:1

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Chromatography, Liquid; Mass Spectrometry; Melatonin; Serotonin; Tryptamines; Tryptophan

2019
Rumen-Protected 5-Hydroxytryptophan Improves Sheep Melatonin Synthesis in the Pineal Gland and Intestinal Tract.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-15, Volume: 25

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Aromatic-L-Amino-Acid Decarboxylases; Arylalkylamine N-Acetyltransferase; Body Weight; Circadian Rhythm; Dietary Supplements; Hydroxyindoleacetic Acid; Intestinal Mucosa; Intestines; Melatonin; Pineal Gland; Rumen; Sheep

2019
Effects of Duodenal 5-Hydroxytryptophan Perfusion on Melatonin Synthesis in GI Tract of Sheep.
    Molecules (Basel, Switzerland), 2021, Aug-31, Volume: 26, Issue:17

    Topics: 5-Hydroxytryptophan; Animal Feed; Animals; Colon; Duodenum; Gastrointestinal Tract; Ileum; Jejunum; Melatonin; Pineal Gland; Sheep

2021
Embryonic Development of Avian Pineal Secretory Activity-A Lesson from the Goose Pineal Organs in Superfusion Culture.
    Molecules (Basel, Switzerland), 2021, Oct-20, Volume: 26, Issue:21

    Topics: 5-Hydroxytryptophan; Animals; Biomarkers; Embryonic Development; Geese; Gene Expression Regulation, Developmental; Light; Melatonin; Norepinephrine; Organogenesis; Photoperiod; Pineal Gland; Serotonin; Tissue Culture Techniques

2021
Changes in the Metabolic Profile of Melatonin Synthesis-Related Indoles during Post-Embryonic Development of the Turkey Pineal Organ.
    International journal of molecular sciences, 2022, Sep-17, Volume: 23, Issue:18

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Circadian Rhythm; Embryonic Development; Hydroxyindoleacetic Acid; Indoles; Melatonin; Metabolome; Pineal Gland; Serotonin; Tryptophan

2022
Hydroxytryptophan biosynthesis by a family of heme-dependent enzymes in bacteria.
    Nature chemical biology, 2023, Volume: 19, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Bacteria; Heme; Humans; Melatonin; Tryptophan

2023
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007