5-hydroxytryptophan and kynurenine

5-hydroxytryptophan has been researched along with kynurenine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (60.00)	18.7374
1990's	3 (7.50)	18.2507
2000's	1 (2.50)	29.6817
2010's	10 (25.00)	24.3611
2020's	2 (5.00)	2.80

Authors

Authors	Studies
Gál, EM; Sherman, AD; Young, RB	1
Fujiwara, M; Hayaishi, O; Hirata, F; Nomiyama, Y; Senoh, S; Shibata, M; Sugimoto, T; Tokuyama, T	1
Handley, SL; Miskin, RC	1
Clark, JA; Clark, MS; Palfreyman, ES; Palfreyman, MG	1
Mori, A; Suzuki, S	1
Kido, R; Minatogawa, Y; Noguchi, T	1
Kido, R; Nakamura, J; Noguchi, T	1
Chruściel, M	1
Hayaishi, O; Hirata, F	1
Kido, R; Noguchi, T; Tsuda, H	1
Chen, NC; Gholson, RK	1
Lapin, IP	1
Dyer, IA; Johnson, RJ	1
Agathopoulos, A; Bafataki, M; Danelatou-Athanassiadou, C; Nicolopoulos, D	1
Kaseda, H; Kido, R; Matsumura, Y; Noguchi, T	1
Bakri, M; Carlson, JR	1
Mattern, G; Viscontini, M	1
Kostellow, AB; Morrill, GA	1
Kido, R; Konishi, N; Noguchì, T	1
Kido, R; Oira, H; Tanaka, H	1
Ababio, BM; Streffer, C	1
Crokaert, R; Geeraerts, F; Schimpfessel, L	1
Fine, RM	1
Baker, H; Gauthier, S; Magnussen, I; Osterland, CK; Sternberg, EM; Van Woert, MH; Young, SN	1
Abe, T; Hamato, H; Takahashi, J; Takahashi, S; Tohgi, H	1
Crouch, RK; Dillon, J; Finley, EL; Schey, KL	1
HAYAISHI, O; SAKAN, T	1
Fotopoulou, C; Hasper, D; Pschowski, R; Reinke, P; Schefold, JC; Schuett, C; Volk, HD; von Haehling, S; Zeden, JP	1
Cheng, SC; Joosten, LA; Kullberg, BJ; Netea, MG; Smeekens, S; van de Veerdonk, F; van der Meer, JW	1
Fedorova, M; Hennig, L; Hoffmann, R; Todorovski, T	1
Fedorova, M; Hoffmann, R; Todorovski, T	1
Brzozowska, I; Brzozowski, T; Drozdowicz, D; Hubalewska-Mazgaj, M; Laidler, PM; Stelmaszynska, T; Zagajewski, J	1
Feng, J; Gruia, F; Li, Y; Polozova, A	1
Budac, DP; Elfving, B; Eskelund, A; Sanchez, C; Wegener, G	1
Barik, S; Rabbani, MAG	1
Cheng, J; Gao, X; Hou, X; Jin, H; Lv, J; Zheng, G	1
Bryn, V; Halvorsen, B; Isaksen, J; Maes, M; Ormstad, H; Saugstad, OD; Skjeldal, OH; Verkerk, R	1
de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP	1
Chen, Y; Guo, M; He, J; Li, Z; Liu, Y; Maitiniyazi, G; Tao, W; Xia, S	1
Goldman, S; Henrottin, J; Laurent, S; Lemaire, C; Luxen, A; Plenevaux, A; Sapunaric, F; Van den Eynde, B; Zervosen, A	1

Reviews

1 review(s) available for 5-hydroxytryptophan and kynurenine

Article	Year
Kynurenines as probable participants of depression. Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1973, Volume: 6, Issue:6 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior; Blood Pressure; Body Temperature; Depression; Dopamine; Drug Interactions; Drug Synergism; Humans; Kynurenine; Mice; Motor Activity; Norepinephrine; ortho-Aminobenzoates; Rats; Serotonin; Serotonin Antagonists; Species Specificity; Sympathetic Nervous System; Tryptamines; Tryptophan	1973

Article

Year

Kynurenines as probable participants of depression.

Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1973, Volume: 6, Issue:6

Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior; Blood Pressure; Body Temperature; Depression; Dopamine; Drug Interactions; Drug Synergism; Humans; Kynurenine; Mice; Motor Activity; Norepinephrine; ortho-Aminobenzoates; Rats; Serotonin; Serotonin Antagonists; Species Specificity; Sympathetic Nervous System; Tryptamines; Tryptophan

1973

Trials

1 trial(s) available for 5-hydroxytryptophan and kynurenine

Article	Year
Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa. The New England journal of medicine, 1980, Oct-02, Volume: 303, Issue:14 Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kynurenine; Levodopa; Male; Middle Aged; Myoclonus; Parkinson Disease; Scleroderma, Systemic; Serotonin	1980

Article

Year

Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.

The New England journal of medicine, 1980, Oct-02, Volume: 303, Issue:14

Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kynurenine; Levodopa; Male; Middle Aged; Myoclonus; Parkinson Disease; Scleroderma, Systemic; Serotonin

1980

Other Studies

38 other study(ies) available for 5-hydroxytryptophan and kynurenine

Article	Year
Tryptophan loading: consequent effects on the synthesis of kynurenine and 5-hydroxyindoles in rat brain. Journal of neurochemistry, 1978, Volume: 31, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Fasting; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan	1978
Formation of 5-hydroxykynurenine and 5-hydroxykynurenamine from 5-hydroxytryptophan in rabbit small intestine. Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Electrophoresis, Paper; Ileum; Isotope Labeling; Kynuramine; Kynurenine; Male; Propiophenones; Rabbits	1979
The interaction of some kynurenine pathway metabolites with 5-hydroxytryptophan and 5-hydroxytryptamine. Psychopharmacology, 1977, Mar-16, Volume: 51, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Hydroxylation; In Vitro Techniques; Kynurenine; Male; Mice; Movement; Muscle Contraction; Muscle, Smooth; Serotonin; Xanthurenates	1977
The effect of tryptophan and a tryptophan/5-hydroxytryptophan combination on indoles in the brains of rats fed a tryptophan deficient diet. Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2 Topics: 3-Hydroxyanthranilic Acid; 5-Hydroxytryptophan; Animals; Brain; Depression; Diet; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase	1975
Regional distribution of tyrosine, tryptophan, and their metabolites in the brain of epileptic El mice. Neurochemical research, 1992, Volume: 17, Issue:7 Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Epilepsy; Kynurenine; Male; Mice; Serotonin; Tryptophan; Tyrosine	1992
Aromatic amino acid transaminases in rat brain. Journal of neurochemistry, 1973, Volume: 20, Issue:5 Topics: 5-Hydroxytryptophan; Ammonium Sulfate; Animals; Brain; Chemical Precipitation; Chromatography, DEAE-Cellulose; Dihydroxyphenylalanine; Ketoglutaric Acids; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase	1973
Aromatic amino acid transaminase in rat intestine. The Biochemical journal, 1973, Volume: 135, Issue:4 Topics: 5-Hydroxytryptophan; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, DEAE-Cellulose; Chromatography, Gel; Intestine, Small; Ketoglutaric Acids; Kinetics; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase	1973
Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats. European journal of pharmacology, 1969, Volume: 8, Issue:2 Topics: 5-Hydroxytryptophan; Aminobenzoates; Animals; Carboxy-Lyases; Cholesterol; Creatinine; Female; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Kynurenine; Liver; Lupus Erythematosus, Systemic; Male; Neutrophils; Proline; Rats; Spleen; Tryptophan; Vanilmandelic Acid	1969
New degradative routes of 5-hydroxytryptophan and serotonin by intestinal tryptophan 2,3-dioxygenase. Biochemical and biophysical research communications, 1972, Jun-09, Volume: 47, Issue:5 Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Chromatography, Paper; Intestines; Kinetics; Kynurenine; Phenols; Rabbits; Serotonin; Spectrophotometry; Tryptophan Oxygenase	1972
5-hydroxytryptophan pyrrolase in rat brain. Journal of neurochemistry, 1972, Volume: 19, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Ascorbic Acid; Brain; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Flavin-Adenine Dinucleotide; Fluorescence; Hydroxylation; In Vitro Techniques; Kynurenic Acid; Kynurenine; Male; Oxygenases; Quinolines; Rats; Rats, Inbred Strains; Spectrum Analysis; Ultraviolet Rays	1972
An improved column chromatographic method for isolation of tryptophan metabolites. Analytical biochemistry, 1972, Volume: 47, Issue:1 Topics: 5-Hydroxytryptophan; Aldehydes; Amides; Animals; Chromatography, DEAE-Cellulose; Colorimetry; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Male; Methods; Nitriles; Rats; Serotonin; Spectrometry, Fluorescence; Tryptamines; Tryptophan; Urea; Vitamin B 6 Deficiency; Xanthurenates	1972
Tryptophan metabolism in the normal and tympanitic bovine. Life sciences, 1968, Jan-15, Volume: 7, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Cattle; Cattle Diseases; Indoleacetic Acids; Kynurenine; Temperature; Tritium; Tryptamines; Tryptophan	1968
Urinary exeretion of phenolic and indolic compounds, metacatecholamines, and VMA by full-term and premature infants. Pediatrics, 1968, Volume: 41, Issue:4 Topics: 5-Hydroxytryptophan; Benzoates; Catecholamines; Cinnamates; Creatinine; Humans; Indoleacetic Acids; Infant, Newborn; Infant, Premature; Kynurenine; Lactates; Mandelic Acids; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Phthalic Acids; Propionates; Tryptophan; Tyrosine	1968
5-hydroxykynurenine decarboxylase in rat intestine. Journal of biochemistry, 1970, Volume: 67, Issue:1 Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carboxy-Lyases; Chromatography, Paper; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Intestine, Small; Kidney; Kynurenine; Male; Mitochondria, Liver; Monoamine Oxidase; Myocardium; Phenylbutyrates; Quinolines; Rats; Spectrophotometry; Tryptophan	1970
Chromatographic separation of tryptophan metabolites. Analytical biochemistry, 1970, Volume: 34 Topics: 5-Hydroxytryptophan; Chromatography, Gel; Chromatography, Ion Exchange; Fluorometry; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Kynurenic Acid; Kynurenine; Methods; Methylcellulose; Picolinic Acids; Pyridines; Serotonin; Spectrophotometry; Tryptamines; Tryptophan; Ultraviolet Rays; Xanthurenates	1970
[Pterin chemistry. Hydroxylation of tryptophan with tetrahydopterin under physiological conditions]. Helvetica chimica acta, 1970, Volume: 53, Issue:4 Topics: 5-Hydroxytryptophan; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Heterocyclic Compounds; Kynurenine; Melanins; Oxygen; Solutions; Tryptophan	1970
Tryptophan induction of the serotonin and kynurenine pathways in the early amphibian embryo. Nature: New biology, 1971, May-26, Volume: 231, Issue:21 Topics: 5-Hydroxytryptophan; Animals; Anura; Carbon Isotopes; Chloramphenicol; Chlorpromazine; Chromatography, Thin Layer; Culture Techniques; Depression, Chemical; Embryo, Nonmammalian; Enzyme Induction; Ethanol; Indoles; Iproniazid; Kynurenine; Melatonin; Mixed Function Oxygenases; Protein Biosynthesis; RNA; Serotonin; Tryptophan; Tryptophan Oxygenase	1971
The pyrrole ring cleavaging enzyme of 5-hydroxytryptophan. Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Apr-22, Volume: 10, Issue:8 Topics: 5-Hydroxytryptophan; Animals; Chromatography, Paper; Chromatography, Thin Layer; Intestine, Small; Kynurenine; Male; Quinolines; Rats	1971
-electronic structures of tryptophan metabolites. I. Tryptophan, kynurenine, anthranilic acid and related compounds. Wakayama medical reports, 1971, Volume: 14, Issue:3 Topics: 5-Hydroxytryptophan; Kynurenine; ortho-Aminobenzoates; Quantum Theory; Tryptophan	1971
[Enzyme activity of aromatic amino acid decarboxylase, kynureninase and kynurenine aminotransferase in the liver of irradiated rats]. Acta radiologica. Supplementum, 1971, Volume: 310 Topics: 5-Hydroxytryptophan; Animals; Dopa Decarboxylase; Dose-Response Relationship, Radiation; Female; Hydrolases; Kynurenine; Liver; Radiation Effects; Rats; Time Factors; Transaminases; Vitamin B 6 Deficiency	1971
The stability of tryptophan metabolites prior to urine analysis. Clinica chimica acta; international journal of clinical chemistry, 1980, Mar-28, Volume: 102, Issue:2-3 Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Cold Temperature; Drug Stability; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Rats; Serotonin; Tryptophan	1980
Drug-related scleroderma-like illness. The Fine page. International journal of dermatology, 1981, Volume: 20, Issue:5 Topics: 5-Hydroxytryptophan; Carbidopa; Drug Combinations; Humans; Kynurenine; Scleroderma, Systemic	1981
Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms. Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1 Topics: 5-Hydroxytryptophan; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Parkinson Disease; Reference Values; Serotonin; Tryptophan	1993
Identification of tryptophan oxidation products in bovine alpha-crystallin. Protein science : a publication of the Protein Society, 1998, Volume: 7, Issue:11 Topics: 5-Hydroxytryptophan; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Crystallins; Kynurenine; Mass Spectrometry; Methionine; Molecular Structure; Oxidation-Reduction; Peptide Fragments; Trypsin; Tryptophan	1998
lambda-Hydroxytryptophan, not an intermediate between tryptophan and kynurenine. The Journal of biological chemistry, 1950, Volume: 186, Issue:1 Topics: 5-Hydroxytryptophan; Humans; Kynurenine; Tryptophan	1950
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6 Topics: 5-Hydroxytryptophan; Adult; Aged; C-Reactive Protein; Case-Control Studies; Creatinine; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Male; Middle Aged; Prognosis; Prospective Studies; Quinolinic Acid; Receptors, Tumor Necrosis Factor, Type I; Renal Dialysis; Renal Insufficiency, Chronic; Serotonin; Tryptophan; Uremia	2009
Candida albicans dampens host defense by downregulating IL-17 production. Journal of immunology (Baltimore, Md. : 1950), 2010, Aug-15, Volume: 185, Issue:4 Topics: 5-Hydroxytryptophan; Candida albicans; Cells, Cultured; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Host-Pathogen Interactions; Hot Temperature; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-17; Interleukin-1beta; Kynurenine; Leukocytes, Mononuclear; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Tryptophan Hydroxylase; Tumor Necrosis Factor-alpha	2010
Synthesis of peptides containing 5-hydroxytryptophan, oxindolylalanine, N-formylkynurenine and kynurenine. Journal of peptide science : an official publication of the European Peptide Society, 2011, Volume: 17, Issue:4 Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Humans; Kynurenine; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Oxindoles; Peptides; Tryptophan	2011
Mass spectrometric characterization of peptides containing different oxidized tryptophan residues. Journal of mass spectrometry : JMS, 2011, Volume: 46, Issue:10 Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Animals; Kynurenine; Molecular Sequence Data; Muscle Proteins; Oxidation-Reduction; Oxindoles; Peptides; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan	2011
Conversion L-tryptophan to melatonin in the gastrointestinal tract: the new high performance liquid chromatography method enabling simultaneous determination of six metabolites of L-tryptophan by native fluorescence and UV-VIS detection. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:6 Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Female; Gastrointestinal Tract; Indoleacetic Acids; Kynurenine; Male; Melatonin; Rats; Rats, Wistar; Serotonin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan	2012
Characterization of the degradation products of a color-changed monoclonal antibody: tryptophan-derived chromophores. Analytical chemistry, 2014, Jul-15, Volume: 86, Issue:14 Topics: 5-Hydroxytryptophan; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Color; Hot Temperature; Kynurenine; Mass Spectrometry; Methionine; Oxidation-Reduction; Peptide Mapping; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays	2014
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism. Neuroscience, 2016, 08-04, Volume: 329 Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous Cycle; Female; Kynurenine; Male; Motor Activity; ortho-Aminobenzoates; Quinolinic Acid; Rats; Resilience, Psychological; Sex Characteristics; Tryptophan	2016
5-Hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus. Virology, 2017, Volume: 503 Topics: 5-Hydroxytryptophan; A549 Cells; Animals; Antiviral Agents; Cell Line, Tumor; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferons; Kynurenine; Macaca mulatta; Parainfluenza Virus 3, Human; Respirovirus Infections; Tryptophan; Virus Replication	2017
Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma. Biochemical and biophysical research communications, 2017, 05-06, Volume: 486, Issue:3 Topics: 5-Hydroxytryptophan; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Disease Progression; Early Diagnosis; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Lymphatic Metastasis; Male; Metabolome; Middle Aged; Prognosis; Serotonin; Tryptophan	2017
Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders. CNS & neurological disorders drug targets, 2018, Volume: 17, Issue:8 Topics: 5-Hydroxytryptophan; Adolescent; Analysis of Variance; Autism Spectrum Disorder; Brain-Derived Neurotrophic Factor; Child; Chromatography, High Pressure Liquid; Electroencephalography; Female; Humans; Kynurenic Acid; Kynurenine; Male; Quinolinic Acid; Tryptophan	2018
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy. Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3 Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Hydroxyindoleacetic Acid; Infant; Kynurenine; Pregnancy; Reproducibility of Results; Serotonin; Tandem Mass Spectrometry; Tryptophan	2023
Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor. Food research international (Ottawa, Ont.), 2023, Volume: 169 Topics: 5-Hydroxytryptophan; Animals; Depression; Female; Kynurenine; Mice; Serotonin; Tryptophan; Whey Proteins	2023
N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase. ACS medicinal chemistry letters, 2015, Mar-12, Volume: 6, Issue:3 Topics:	2015