5-hydroxytryptophan has been researched along with hydrazine in 179 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 136 (75.98) | 18.7374 |
| 1990's | 27 (15.08) | 18.2507 |
| 2000's | 10 (5.59) | 29.6817 |
| 2010's | 6 (3.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlsson, A; Holmin, T; Lindqvist, M; Siesjö, BK | 1 |
| Hedner, T; Lundborg, P | 3 |
| Tyce, GM; Wong, KL | 2 |
| Chadwick, D; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
| Autret, A; Bussel, B; Castaigne, P; Cathala, HP; Minz, M | 1 |
| Korf, J; Sebens, JB; van Wijk, M | 1 |
| Borri, P; Borri-Voltattorni, C; Minelli, A | 1 |
| de Fine Olivarius, B; Dupont, E; Magnussen, I; Prange-Hansen, A | 1 |
| Benignus, VA; Davis, JN; McNamara, MC; Miller, AT | 1 |
| MacMillan, V | 2 |
| de Fine Olivarius, B; Dupont, E; Engbaek, F; Magnussen, I | 1 |
| Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD | 1 |
| Bowers, MB; Howieson, J; Rosenbaum, D; Van Woert, MH | 1 |
| Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
| Gillin, JC; Magyar, RL; Wyatt, RJ | 1 |
| Sethy, VH; Van Woert, MH | 2 |
| Stancer, HC; Warsh, JJ | 2 |
| Kato, N; Murase, Y | 1 |
| Kehr, W | 1 |
| Aghajanian, GK; Gallager, DW | 1 |
| Korf, J; Lequin, RM; van Praag, HM | 1 |
| Engel, J; Katzman, R; Sharpless, N; Thal, L; Wolfson, L | 1 |
| Chapman, B; Feldman, JM | 1 |
| Brokaw, JJ; Hausz, JA; Matheson, GK; Tunnicliff, G; White, GW | 1 |
| Chen, CC | 1 |
| Andersson, Y; Bjurling, P; Hartvig, P; Långström, B; Lindner, KJ; Tedroff, J | 1 |
| Engberg, G; Nissbrandt, H; Pileblad, E | 1 |
| Cano, J; Herrera, AJ; Machado, A; Santiago, M; Venero, JL; Vizuete, ML | 1 |
| Nilsson, GE | 1 |
| Curzon, G; O'Connell, MT; Portas, CM; Sarna, GS | 1 |
| Cano, J; Machado, A; Venero, JL | 1 |
| Ahlenius, S; Hillegaart, V; Hjorth, S; Larsson, K | 1 |
| Hänninen, H; Huupponen, R; Koulu, M; Pesonen, U; Rouru, J; Seppälä, T | 1 |
| Burian, MA; Freeman, JP; Szmuszkovicz, J; Vonvoigtlander, PF; Wang, WY | 1 |
| Ahlenius, S; Hillegaart, V; Hjorth, S | 1 |
| Kalant, H; Speisky, MB | 1 |
| Mehendale, HM; Prasada Rao, KS | 1 |
| Hayaishi, O; Kagamiyama, H; Suzuki, S; Tsubokura, S; Watanabe, Y | 1 |
| Ahlenius, S; Hillegaart, V; Wijkström, A | 1 |
| King, TS; Steger, RW; Steinlechner, S | 1 |
| Goodrich, C; Lechner, R; Slone, W | 1 |
| Barraclough, CA; Hartman, RD; Petersen, SL | 1 |
| Feldman, RS; McElroy, JF; Meyer, JS | 1 |
| Mitchell, SN; Thomas, PJ | 1 |
| Moore, KE; Shannon, NJ | 2 |
| Carlsson, A; Engberg, G; Magnusson, T; Nissbrandt, H; Wikström, H | 1 |
| Wambebe, C | 1 |
| Rabin, RA; Winter, JC | 1 |
| Battegay, R; Gastpar, M; Zmilacher, K | 1 |
| Denoroy, L; Fety, R; Renaud, B; Sassard, J; Tappaz, ML; Vincent, M | 1 |
| Duda, NJ; Moore, KE | 1 |
| Korf, J; Postema, F; Venema, K | 1 |
| Carlsson, A; Lindqvist, M | 3 |
| Gardey-Levassort, C; Lechat, P | 1 |
| Bourgoin, S; Glowinski, J; Hamon, M; Ley, JP; Morot-Gaudry, Y | 1 |
| Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ | 1 |
| Chruściel, M | 1 |
| De la Torre, JC; Kawanaga, HM; Mullan, S | 1 |
| Bédard, P; Carlsson, A; Lindqvist, M | 1 |
| Krip, G; Vazquez, AJ | 1 |
| Senault, B | 1 |
| Modigh, K | 2 |
| Carlsson, A; Kehr, W; Lindqvist, M | 1 |
| Norberg, KA | 1 |
| Eidelberg, E; Long, M; Miller, MK | 1 |
| Weber, LJ | 1 |
| Quay, WB | 1 |
| Gylys, JA; Muccia, PM | 1 |
| Axelrod, J; Snyder, SH; Zweig, M | 1 |
| Airaksinen, MM; Mattila, K | 1 |
| Bartholini, G; Da Prada, M; Pletscher, A | 1 |
| Boggan, W; Freedman, DX; Schlesinger, K | 1 |
| Flock, EV; Owen, CA; Tyce, GM | 1 |
| Wooley, DF | 1 |
| Klingman, GI | 1 |
| Gershon, MD; Nunez, EA | 1 |
| Hamilton, AE; Horita, A | 1 |
| Segawa, T | 1 |
| Boggan, WO; Freedman, DX; Schlesinger, K | 1 |
| Butcher, LL; Engel, J; Fuxe, K | 2 |
| Lahti, RA; Platz, PA | 1 |
| Gershon, MD; Robinson, RG | 1 |
| Dineen, JK; Love, RJ; Rothwell, TL | 1 |
| Girault, JM; Jacob, J; Peindaries, R | 1 |
| Segawa, T; Takagi, H; Takatsuka, K | 1 |
| Atack, CV; Carlsson, A; Davis, JN; Kehr, W; Lindqvist, M | 1 |
| Hamilton, AE; Horita, A; Nair, X | 1 |
| Butcher, LL; Rhodes, DL; Yuwiler, A | 1 |
| Fjalland, B; Hyttel, J | 1 |
| Kellogg, C; Lundborg, P | 1 |
| Hare, TA; Mahoney, K; Vogel, WH | 1 |
| Chase, TN; Colburn, RW; Kopin, IJ; Ng, LK | 1 |
| Boggan, WO; Seiden, LS | 1 |
| Carruba, M; Da Prada, M; O'Brien, A; Pletscher, A; Saner, A | 1 |
| Carlsson, A; Davis, JN; MacMillan, V; Siesjö, BK | 1 |
| Malmnäs, CO | 1 |
| Bailey, PT; Bose, S; Pradhan, SN; Thoa, NB | 1 |
| Gardey-Levassort, C; Lechat, P; Olive, G | 1 |
| Bocknik, SE; Kulkarni, AS | 1 |
| Brown, RM; Carlsson, A; Snider, SR | 1 |
| Buser, P; Viala, D | 1 |
| Galanter, M; Green, R; Kaplan, J; Vaughan, T; Wyatt, RJ | 1 |
| Chase, TN; Ng, LK; Watanabe, AM | 1 |
| Andén, NE; Engel, J | 1 |
| Anagnoste, B; Battista, AF; Fuxe, K; Goldstein, M; Ohmoto, T | 1 |
| Håkanson, R; Lilja, B; Owman, C; Thunell, S | 1 |
| Duhault, J; Gonnard, P; Nguyen-Philippon, C | 1 |
| Gershon, MD; Ross, LL | 1 |
| Matthies, H; Popov, N; Rösler, V | 1 |
| Madras, BK; Sourkes, TL | 1 |
| Langendorff, H; Langendorff, M; Streffer, C | 1 |
| Louis, WJ; Sjoerdsma, A; Spector, S; Tabei, R | 1 |
| Chase, TN | 1 |
| De la Torre, JC | 1 |
| Bartholini, G; Constantinidis, J; Pletscher, A; Tissot, R | 1 |
| Fuller, RW; Perry, KW | 1 |
| Beretta, E; de Crousaz, G; Regli, F; Steck, AJ | 1 |
| Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Pujol, JF; Riou, F | 1 |
| Baker, PC; Goodrich, CA | 1 |
| Magnussen, I; Van Woert, MH | 1 |
| Crowley, WR; Johnson, MD | 1 |
| Bazil, CW; Fernstrom, JD; Fernstrom, MH | 1 |
| Ribeiro, P; Webb, RA | 1 |
| Shelekhov, SL; Val'dman, AV | 1 |
| Trouillas, P | 1 |
| Pujol, JF; Tappaz, ML | 1 |
| Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN | 1 |
| Ahlenius, S; Berggren, U; Engel, J | 1 |
| Persson, B; Svensson, TH | 1 |
| Geller, I; Hartmann, RJ; Messiha, FS | 1 |
| Shum, A; Sole, MJ; Van Loon, GR | 1 |
| Adeleine, P; Bard, J; Brudon, F; Garde, A; Renaud, B; Robert, JM; Trouillas, P | 1 |
| Bartke, A; Cecim, M; Fadden, C; Kerr, J; Steger, RW | 1 |
| Alfaro, MJ; Colado, MI; Martin, MI; Ormazabal, MJ | 1 |
| Denoroy, L; Jouvet, M; Poncet, L | 1 |
| Hashiguti, H; Ikeda, T; Maruyama, W; Nakahara, D; Naoi, M | 1 |
| Gobert, A; Lejeune, F; Millan, MJ; Rivet, JM | 1 |
| Ahlenius, S; Ericson, E; Wijkström, A | 1 |
| Boadle-Biber, MC; Dilts, RP | 1 |
| Baĭchurina, AZ; Garaev, RS; Semina, II | 1 |
| López de Pablo, AL; Marco, EJ; Moreno, MJ | 1 |
| Dalmaz, Y; Denoroy, L; Pequignot, JM; Poncet, L | 1 |
| Martín, MI; Milanés, MV; Ormazábal, MJ | 1 |
| Hashiguchi, H; Ishida, Y; Ishizuka, Y; Kuwahara, I; Mitsuyama, Y; Nakane, H; Nishimori, T; Todaka, K; Uchimura, D | 1 |
| Ahlenius, S; Henriksson, I; Magnusson, O; Salmi, P | 1 |
| Nakahara, D; Nakamura, M | 1 |
| Liburdy, R; Mori, A; Noda, Y; Packer, L | 1 |
| Ishida, Y; Nakahara, D; Nakamura, M; Oki, Y | 1 |
| Furukawa, H; Furuno, N; Nakahara, D; Nakamura, M | 1 |
| Connor, TJ; Kelly, JP; Leonard, BE; Nolan, Y | 1 |
| Ross, SB; Stenfors, C | 1 |
| BARRE, N; CAHN, J; HEROLD, M | 1 |
| KUNZ, E | 1 |
| IMAIZUMI, R; MATSUOKA, M; YOSHIDA, H | 1 |
| CLARK, WG; FLEMING, RM; HANSSON, E | 1 |
| PLETSCHER, A; PRADAM, DA; STEINER, FA | 1 |
| Esteban, S; García-Sevilla, JA; Moranta, D | 1 |
| Blomquist, G; Hagberg, GE; Hammarlund-Udenaes, M; Hartvig, P; Långström, B; Lundquist, P; Torstenson, R | 1 |
| Conley, RK; Hutson, PH; Ivarsson, M; Li, J | 1 |
| Ashford, KA; Christie, IN; Evans, AK; Lowry, CA; Reinders, N; Wakerley, JB | 1 |
| Evans, AK; Heerkens, JL; Lowry, CA | 1 |
| de Boer, SF; Koolhaas, JM; Natarajan, D | 1 |
| Buckley, KN; Gigliucci, V; Harkin, A; Nunan, J; O'Shea, K | 1 |
| Domino, EF; Jutkiewicz, EM; Ohmura, Y; Yoshioka, M | 1 |
| Choi, S; DiSilvio, B; Fernstrom, JD; Fernstrom, MH | 1 |
| Buchwalow, IB; Gergs, U; Hauptmann, S; Neumann, J; Pönicke, K | 1 |
| de Vries, EF; Di Gialleonardo, V; Dierckx, RA; Kema, IP; Ramakrishnan, NK; van Waarde, A; Visser, AK; Willemsen, AT | 1 |
| Andreatti Filho, RL; Baptista, AA; Donato, TC; Garcia, KC; Okamoto, AS; Sequeira, JL; Smaniotto, BD | 1 |
2 trial(s) available for 5-hydroxytryptophan and hydrazine
| Article | Year |
|---|---|
Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Brain; Carboxy-Lyases; Clinical Trials as Topic; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Paranoid Disorders; Placebos; Schizophrenia; Serotonin | 1972 |
Parkinson's disease. Modification by 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aged; Brain; Carboxy-Lyases; Clinical Trials as Topic; Drug Synergism; Evaluation Studies as Topic; Extrapyramidal Tracts; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates; Placebos; Serotonin | 1972 |
177 other study(ies) available for 5-hydroxytryptophan and hydrazine
| Article | Year |
|---|---|
Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Brain; Carbohydrate Metabolism; Carbon Dioxide; Dihydroxyphenylalanine; Hydrazines; Hydrogen-Ion Concentration; Hydroxylation; Hypercapnia; Male; Partial Pressure; Phosphates; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1977 |
Regional changes in monoamine synthesis in the developing rat brain during hypoxia.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Hydrazines; Hypoxia, Brain; Nitrous Oxide; Oxygen Consumption; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1979 |
Pyridoxal 5'-phosphate levels in brain after treatments which impair cerebral glucose metabolism.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Brain; Cyclopropanes; Glucose; Hepatectomy; Hydrazines; Levodopa; Male; Monoamine Oxidase Inhibitors; Phenyl Ethers; Pyridoxal Phosphate; Rats | 1979 |
Manipulation of brain serotonin in the treatment of myoclonus.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Benzodiazepinones; Brain; Carbidopa; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Infusions, Parenteral; Male; Middle Aged; Myoclonus; Serotonin | 1975 |
Human sleep and 5-HTP. Effects of repeated high doses and of association with benserazide (RO.04.4602).
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Drug Combinations; Electroencephalography; Humans; Hydrazines; Male; Mental Processes; Sleep Stages | 1976 |
Probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Blood-Brain Barrier; Brain; Brain Chemistry; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tryptophan | 1979 |
Interaction of N-(DL-seryl)N'-(2,3,4-trihydroxybenzyl)-hydrazine with L-dopa decarboxylase from pig kidney.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Dopa Decarboxylase; Hydrazines; Kidney; Kinetics; Levodopa; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine; Tyrosine | 1977 |
Palatal myoclonus treated with 5-hydroxytryptophan and a decarboxylase-inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Combinations; Humans; Hydrazines; Male; Muscle Contraction; Myoclonus; Palate | 1977 |
Age related changes in the effect of electroconvulsive shock (ECS) on the in vivo hydroxylation of tyrosine and tryptophan in rat brain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Alcohols; Brain; Dihydroxyphenylalanine; Electroshock; Hydrazines; Male; Rats; Tryptophan; Tyrosine | 1977 |
The effects of acute hypercapnia on cerebral indole amine metabolism.
Topics: 5-Hydroxytryptophan; Amines; Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Hypercapnia; Indoles; Male; Pargyline; Probenecid; Rats; Serotonin; Tryptophan | 1978 |
Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Hypoxia; Male; Myoclonus | 1978 |
Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Carbidopa; Child; Drug Therapy, Combination; Humans; Hydrazines; Lesch-Nyhan Syndrome; Male; Movement Disorders; Self Mutilation; Sleep; Wakefulness | 1978 |
Effect of administration of 5-hydroxytryptophan and an inhibitor of L-aromatic amino acid decarboxylase on glucose metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Blood Glucose; Brain; Brain Chemistry; Glucose; Glutamates; Hydrazines; Male; Rats; Serotonin | 1979 |
Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbidopa; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydrazines; Hypoxia, Brain; Long-Term Care; Male; Middle Aged; Myoclonus; Serotonin; Tryptophan | 1977 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsy, Post-Traumatic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Isocarboxazid; Male; Methysergide; Middle Aged; Myoclonus; Premedication; Tryptophan | 1977 |
Tolerance to the increased locomotor activity produced by L-5-hydroxytryptophan following peripheral decarboxylase inhibition in mice.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Drug Tolerance; Hydrazines; Male; Mice; Motor Activity; Time Factors | 1978 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin | 1975 |
The origin of blood k-hydroxyindoleacetic acid following L-hydrazino-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
The origin of blood 5-hydroxyindoleacetic acid following L-hydrazine-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
A histochemical study on the central effect of monoamine precursors.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Brain Chemistry; Capillaries; Cerebral Ventricles; Dopamine; Drug Combinations; Hydrazines; Levodopa; Male; Median Eminence; Norepinephrine; Rats; Serotonin; Substantia Nigra | 1975 |
Influence of L-3-methoxytyrosine on monoamine synthesis in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Liver; Male; Myocardium; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine | 1975 |
Inhibition of firing of raphe neurones by tryptophan and 5-hydroxytryptophan: blockade by inhibiting serotonin synthesis with Ro-4-4602.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Depression, Chemical; Hydrazines; Iontophoresis; Lysergic Acid Diethylamide; Male; Mesencephalon; Nervous System; Neural Pathways; Neurons; Rats; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan | 1976 |
An unexpected effect of L-5 hydroxytryptophan-ethyl-ester combined with a peripheral decarboxylase inhibitor on human serum prolactin.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carboxy-Lyases; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Infusions, Parenteral; Male; Middle Aged; Prolactin; Serotonin | 1976 |
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Myoclonus; Serotonin | 1976 |
Monoamine oxidase inhibitors: nature of their interaction with rabbit pancreatic islets to alter insluin secretion.
Topics: 5-Hydroxytryptophan; Animals; Dopamine; Dose-Response Relationship, Drug; Harmine; Hydrazines; Insulin; Insulin Secretion; Iproniazid; Islets of Langerhans; Levodopa; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Rabbits; Serotonin; Time Factors; Tranylcypromine; Tryptamines | 1975 |
Influence of repeated treatment with buspirone on central 5-hydroxytryptamine and dopamine synthesis.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Buspirone; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Female; Hydrazines; Rats; Rats, Sprague-Dawley; Serotonin | 1992 |
Effect of the duration of streptozotocin-induced diabetes on turnover of central biogenic amines in mice.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Catecholamines; Corpus Striatum; Diabetes Mellitus, Experimental; Dihydroxyphenylalanine; Hydrazines; Hypothalamus; Male; Medulla Oblongata; Mice; Mice, Inbred ICR; Pons; Serotonin; Time Factors | 1992 |
Brain kinetics of 11 C-labelled L-tryptophan and 5-hydroxy-L-tryptophan in the rhesus monkey. A study using positron emission tomography.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Radioisotopes; Female; Hydrazines; Macaca mulatta; Monoamine Oxidase Inhibitors; Tomography, Emission-Computed; Tryptophan | 1992 |
The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Cerebral Cortex; Corpus Striatum; Desipramine; Dihydroxyphenylalanine; Dopamine; Hydrazines; Limbic System; Locus Coeruleus; Male; Maprotiline; Methyltyrosines; Neurotransmitter Uptake Inhibitors; Norepinephrine; Normetanephrine; Oxidopamine; Pargyline; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Synaptic Transmission | 1991 |
Effects of neonatal bilateral eye enucleation on postnatal development of the monoamines in posterior thalamus of the rat.
Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; Dihydroxyphenylalanine; Dopamine; Eye Enucleation; Hydrazines; Male; Monoamine Oxidase; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Thalamus; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1991 |
Turnover of serotonin in brain of an anoxia-tolerant vertebrate, the crucian carp.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carps; Cyprinidae; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Pargyline; Serotonin; Time Factors; Tissue Distribution | 1990 |
Effect of p-chlorophenylalanine on release of 5-hydroxytryptamine from the rat frontal cortex in vivo.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Cerebral Cortex; Dialysis; Electrochemistry; Fenclonine; Frontal Lobe; Hydrazines; Hydroxyindoleacetic Acid; Male; Perfusion; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Age effects on monoamine turnover of the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydrazines; In Vitro Techniques; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1991 |
Effects of sexual interactions on the in vivo rate of monoamine synthesis in forebrain regions of the male rat.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Mapping; Copulation; Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Female; Hydrazines; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Serotonin; Sexual Behavior, Animal | 1991 |
Hypothalamic neurochemistry and feeding behavioral responses to clonidine, an alpha-2-agonist, and to trifluoromethylphenylpiperazine, a putative 5-hydroxytryptamine-1B agonist, in genetically obese Zucker rats.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Blood Glucose; Catecholamines; Clonidine; Dihydroxyphenylalanine; Feeding Behavior; Hydrazines; Hypothalamus; Insulin; Obesity; Piperazines; Rats; Rats, Zucker; Receptors, Serotonin; Serotonin | 1990 |
Synthesis and biological activity of 2-amino-1-oxa-2,3-dihydro-1-H-phenalene derivatives.
Topics: 5-Hydroxytryptophan; Animals; Antipsychotic Agents; Brain Chemistry; Dihydroxyphenylalanine; Heterocyclic Compounds; Hydrazines; Oxidation-Reduction; Phenalenes; Rats; Receptors, Dopamine; Receptors, Serotonin | 1990 |
Effects of 5-HT and 8-OH-DPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Frontal Lobe; Hydrazines; Male; Naphthalenes; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1990 |
Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures.
Topics: 5-Hydroxytryptophan; Animals; Arginine Vasopressin; Drug Tolerance; Ethanol; Hippocampus; Hydrazines; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Motor Activity; Rats; Rats, Inbred Strains; Septum Pellucidum; Serotonin | 1986 |
A comparison of the effects of carbon monoxide intoxication and low-oxygen gas mixtures on cerebral biogenic amine metabolism.
Topics: 5-Hydroxytryptophan; Animals; Carbon Monoxide Poisoning; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Precursor utilization of 5-hydroxytryptophan for 5-hydroxytryptamine biosynthesis in isolated and perfused rabbit and rat lungs.
Topics: 5-Hydroxytryptophan; Animals; Chlorphentermine; Hydrazines; Hydroxyindoleacetic Acid; Lung; Perfusion; Rabbits; Rats; Serotonin | 1987 |
Decrease in tetrahydrobiopterin content and neurotransmitter amine biosynthesis in rat brain by an inhibitor of guanosine triphosphate cyclohydrolase.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Aminohydrolases; Animals; Biogenic Amines; Biopterins; Brain; Dihydroxyphenylalanine; Dopamine; GTP Cyclohydrolase; Hydrazines; Hydroxyindoleacetic Acid; Hypoxanthines; Liver; Male; Neurotransmitter Agents; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Ergolines; Hydrazines; Limbic System; Male; Naphthalenes; Piperidines; Quinpirole; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tetrahydronaphthalenes; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1989 |
Comparison of diurnal and nocturnal rates of 5-hydroxytryptamine turnover in the rat mediobasal hypothalamus.
Topics: 5-Hydroxytryptophan; Animals; Circadian Rhythm; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus, Middle; Male; Pargyline; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Central versus peripheral effects on temperature preference and body temperature following alteration of 5-HT in maturing mice.
Topics: 5-Hydroxytryptophan; Aging; Amidines; Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Carbidopa; Carboxy-Lyases; Central Nervous System; Double-Blind Method; Drug Interactions; Hydrazines; Injections, Intraperitoneal; Mice; Peripheral Nerves; Piperidines; Serotonin Antagonists | 1989 |
An analysis of serotonin secretion in hypothalamic regions based on 5-hydroxytryptophan accumulation or push-pull perfusion. Effects of mesencephalic raphe or locus coeruleus stimulation and correlated changes in plasma luteinizing hormone.
Topics: 5-Hydroxytryptophan; Animals; Electric Stimulation; Enzyme Inhibitors; Female; Hydrazines; Hypothalamus; Locus Coeruleus; Luteinizing Hormone; Ovariectomy; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1989 |
A comparison between chlordiazepoxide and CL 218,872, a synthetic non-benzodiazepine ligand for benzodiazepine receptors, on serotonin and catecholamine turnover in brain.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Biotransformation; Brain; Catecholamines; Chlordiazepoxide; Dihydroxyphenylalanine; Hydrazines; Male; Pyridazines; Rats; Receptors, GABA-A; Serotonin | 1986 |
Effect of restraint stress and anxiolytics on 5-HT turnover in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Brain; Buspirone; Chlordiazepoxide; Chromatography, High Pressure Liquid; Hydrazines; Male; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin; Stress, Psychological; Time Factors | 1988 |
5-Hydroxytryptamine is synthesized in neurons terminating in the neural and intermediate lobes of the rat pituitary gland.
Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Electric Stimulation; Fluoxetine; Hydrazines; Male; Neurons; Osmolar Concentration; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1987 |
NSD 1034: an amino acid decarboxylase inhibitor with a stimulatory action on dopamine synthesis not mediated by classical dopamine receptors.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1988 |
Influence of some agents that affect 5-hydroxytryptamine metabolism and receptors on nitrazepam-induced sleep in mice.
Topics: 5-Hydroxytryptophan; Animals; Benzodiazepinones; Citalopram; Cyproheptadine; Drug Synergism; Fenclonine; Flumazenil; Hydrazines; Lysergic Acid Diethylamide; Male; Methiothepin; Mice; Nitrazepam; Propylamines; Receptors, Serotonin; Serotonin; Sleep | 1985 |
A comparison of the discriminative stimulus properties of l-5-hydroxytryptophan in the presence of either citalopram or Ro 4-4602.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Citalopram; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Hydrazines; Male; Rats; Rats, Inbred F344 | 1988 |
L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Aged; Benserazide; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Psychological Tests; Retrospective Studies | 1988 |
Determination of the source of 5-hydroxytryptaminergic neuronal projections to the neural and intermediate lobes of the rat pituitary gland through the use of electrical stimulation and lesioning experiments.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Electric Stimulation; Hydrazines; Hypothalamus, Middle; Male; Neural Pathways; Neurons; Pituitary Gland; Raphe Nuclei; Rats; Serotonin | 1987 |
Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Hydrazines; Hydroxylation; Hypertension; Hypothalamus; Medulla Oblongata; Raphe Nuclei; Rats; Rats, Mutant Strains; Tryptophan | 1985 |
Simultaneous determination of 5-hydroxytryptophan and 3,4-dihydroxyphenylalanine in rat brain by HPLC with electrochemical detection following electrical stimulation of the dorsal raphe nucleus.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Electric Stimulation; Hydrazines; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors; Tissue Distribution | 1985 |
Letter: Treatment of post-anoxic intention myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus | 1974 |
Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system.
Topics: 5-Hydroxytryptophan; Animals; Autoanalysis; Brain; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Phenylalanine; Rats; Serotonin; Staining and Labeling; Stereotaxic Techniques; Time Factors | 1974 |
In-vivo measurements of tryptophan and tyrosine hydroxylase activities in mouse brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Female; Hydrazines; Hydroxyindoleacetic Acid; Mice; Norepinephrine; Pargyline; Serotonin; Tryptophan; Tyrosine 3-Monooxygenase | 1973 |
Dose-dependent potentiation or inhibition by Ro4-4602 of 5-HTP hyperthermia in rabbits.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypothalamus; Rabbits | 1974 |
Estimation of the rate of 5-HT synthesis in the mouse brain by various methods.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Chromatography, Ion Exchange; Female; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Mice; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Serotonin; Spectrometry, Fluorescence; Tritium; Tryptophan | 1974 |
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors | 1974 |
Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats.
Topics: 5-Hydroxytryptophan; Aminobenzoates; Animals; Carboxy-Lyases; Cholesterol; Creatinine; Female; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Kynurenine; Liver; Lupus Erythematosus, Systemic; Male; Neutrophils; Proline; Rats; Spleen; Tryptophan; Vanilmandelic Acid | 1969 |
Seizure susceptibility after manipulation of brain serotonin.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Brain; Drug Antagonism; Fenclonine; Hydrazines; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Serotonin | 1970 |
Effect of a transverse cerebral hemisection on 5-hydroxytryptamine metabolism in the rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carboxy-Lyases; Diencephalon; Female; Hydrazines; Hydroxyindoleacetic Acid; Male; Mesencephalon; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tryptophan | 1972 |
The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Benzyl Compounds; Brain; Carboxy-Lyases; Dimethylamines; Dose-Response Relationship, Drug; Feedback; Female; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Mice; Nialamide; Phenylalanine; Reserpine; Sensory Receptor Cells; Serine; Serotonin; Tryptamines; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 1972 |
Interactions between amphetamine and serotonergic agents on cat's isolated cerebral cortex.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain Chemistry; Cats; Cerebral Cortex; Cyproheptadine; Dextroamphetamine; Electroencephalography; Female; Fenclonine; Hydrazines; Male; Phentolamine; Serotonin | 1973 |
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clonidine; Dihydroxyphenylalanine; Dioxoles; Disulfides; Fenclonine; Humans; Hydrazines; Hydroxybutyrates; Imidazoles; Iproniazid; Male; Methyldopa; Methyltyrosines; Phenoxybenzamine; Piperazines; Rats; Reserpine; Serotonin; Thiocarbamates; Time Factors | 1974 |
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine | 1974 |
Effect of pentobarbitone and diethyl ether on the synthesis of monoamines in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Body Temperature; Brain; Brain Stem; Cerebellum; Corpus Striatum; Diencephalon; Dihydroxyphenylalanine; Drug Interactions; Ethyl Ethers; Hydrazines; Hypothermia, Induced; Injections, Intraperitoneal; Limbic System; Male; Pentobarbital; Rats; Stimulation, Chemical | 1974 |
Drug-induced changes in monoamine levels in the sympathetic adrenergic ganglion cells and terminals. A histochemical study.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Ephedrine; Ganglia, Autonomic; Hydrazines; Methyldopa; Microscopy, Fluorescence; Nerve Endings; Neurochemistry; Nialamide; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine | 1965 |
Spectrum analysis of electroencephalographic changes induced by some psychoactive agents. Their possible relationship to changes in cerebral biogenic amine levels.
Topics: 5-Hydroxytryptophan; Animals; Cats; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Hydrazines; Mice; Norepinephrine; Physostigmine; Rabbits; Rats; Reserpine; Serotonin; Spectrum Analysis | 1966 |
Influence of monoamine oxidase inhibitors on 5-hydroxytryptamine synthesis in the brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Hydrazines; In Vitro Techniques; Iproniazid; Monoamine Oxidase Inhibitors; Pargyline; Rats; Serotonin; Tryptophan | 1966 |
Rhythmic and light-induced changes in levels of pineal 5-hydroxyindoles in the pigeon (Columba livia).
Topics: 5-Hydroxytryptophan; Animals; Birds; Chromatography, Thin Layer; Circadian Rhythm; Fluorometry; Hydrazines; Hydroxyindoleacetic Acid; Light; Pineal Gland; Serotonin; Sympatholytics | 1966 |
Modaline and locomotor activity in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Dextroamphetamine; Dihydroxyphenylalanine; Enzymes; Hydrazines; Mice; Monoamine Oxidase Inhibitors; Motor Skills; Phenelzine; Tranylcypromine; Tyrosine | 1967 |
Circadian rhythm in the serotonin content of the rat pineal gland: regulating factors.
Topics: 5-Hydroxytryptophan; Animals; Carbon Isotopes; Carboxy-Lyases; Circadian Rhythm; Dactinomycin; Darkness; Female; Hydrazines; Light; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pineal Gland; Puromycin; Rats; Serotonin; Tryptophan | 1967 |
Urinary and gastrointestinal excretion of metabolites of labelled 5-hydroxytryptamine and 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Bile; Carbon Isotopes; Cats; Chromatography, Paper; Gastric Juice; Hydrazines; Infusions, Parenteral; Intestinal Secretions; Intestines; Male; Methysergide; Rabbits; Rats; Reserpine; Serotonin | 1967 |
Decrease of cerebral 5-hydroxytryptamine by 3,4-dihydroxyphenylalanine after inhibition of extracerebral decarboxylase.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Hydrazines; Hydroxyindoleacetic Acid; Rats; Serotonin; Tritium | 1968 |
Genetics of audiogenic seizures: II. Effects of pharmacological manipulation of brain serotonin, norepinephrine and gamma-aminobutyric acid.
Topics: 5-Hydroxytryptophan; Aminobutyrates; Animals; Brain Chemistry; Hearing Loss, Noise-Induced; Hydrazines; Injections, Intraperitoneal; Iproniazid; Methyltyrosines; Mice; Norepinephrine; Pyridoxine; Reserpine; Serotonin; Tetrabenazine | 1968 |
Metabolism of serotonin by the isolated perfused rat liver--effect of glucuronyl transferase deficiency or monoamine oxidase inhibition.
Topics: 5-Hydroxytryptophan; Animals; Bile; Blood Platelets; Carbon Isotopes; Chromatography, Paper; Depression, Chemical; Glucosyltransferases; Glucuronates; Hydrazines; Hydroxyindoleacetic Acid; In Vitro Techniques; Liver; Metabolism, Inborn Errors; Molecular Biology; Monoamine Oxidase; Perfusion; Rats; Serotonin; Sulfates | 1968 |
Effects of manipulation of biogenic amine levels upon spinal cord reflexes.
Topics: 5-Hydroxytryptophan; Acetates; Animals; Autonomic Agents; Cats; Dihydroxyphenylalanine; Glycolates; Hydrazines; Norepinephrine; Reflex; Reflex, Monosynaptic; Reserpine; Serotonin; Spinal Cord; Thiocarbamates; Thiosemicarbazones | 1968 |
5-hydroxytryptamine levels in peripheral organs of immunosympathectomized rats.
Topics: 5-Hydroxytryptophan; Animals; Body Weight; Brain Chemistry; Brain Stem; Cecum; Female; Fluorometry; Ganglia, Autonomic; Growth Substances; Hydrazines; Intestines; Liver; Lung; Male; Myocardium; Nerve Growth Factors; Nerve Tissue; Organ Size; Rats; Serotonin; Spectrophotometry; Spinal Cord; Spleen; Submandibular Gland; Uterus | 1969 |
Histochemical and radioautographic studies of serotonin and parafollicular cells in the thyroid gland of the prehibernating bat.
Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Chiroptera; Chromatography, Thin Layer; Cytoplasmic Granules; Hibernation; Histocytochemistry; Hydrazines; Microscopy, Fluorescence; Serotonin; Thyroid Gland; Tritium | 1970 |
Potentiation of the central actions of 5-hydroxytryptophan in rabbits by DL-alpha-hydrazino-alpha-methyldopa.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Central Nervous System; Drug Synergism; Hydrazines; Methyldopa; Rabbits | 1970 |
Effects of reserpine and desipramine on the uptake and subcellular distribution of 5-hydroxytryptamine in rabbit brain stem after intravenous administration of 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Centrifugation, Density Gradient; Desipramine; Hydrazines; Injections, Intravenous; Male; Rabbits; Reserpine; Serotonin; Ultracentrifugation | 1970 |
Genetics of audiogenic seizures. 3. Time response relationships between drug administration and seizure susceptibility.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Brain; Brain Chemistry; Female; Hydrazines; Iproniazid; Male; Methyltyrosines; Mice; Norepinephrine; Phenylalanine; Reserpine; Seizures; Serotonin; Sound; Time Factors | 1970 |
Accumulation of 5-hydroxytryptophan in mouse brain after decarboxylase inhibition.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carboxy-Lyases; Female; Hydrazines; Mice; Serotonin | 1970 |
DL-5-hydroxytryptophan-induced changes in central monoamine neurons after peripheral decarboxylase inhibition.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Capillaries; Dopamine; Histocytochemistry; Hydrazines; Male; Microscopy, Fluorescence; Nerve Endings; Neurons; Norepinephrine; Rats; Serotonin | 1971 |
Selective protection of serotonin stores against the action of reserpine by -methyl-5-hydroxytryptpohan pretreatment.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Chromatography, Ion Exchange; Fluorometry; Hydrazines; Injections, Intraperitoneal; Male; Mice; Norepinephrine; Reserpine; Serotonin; Time Factors; Tritium | 1969 |
Synthesis and uptake of 5-hydroxytryptamine by the myenteric plexus of the guinea-pig ileum. A histochemical study.
Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Autoradiography; Fenclonine; Formaldehyde; Guinea Pigs; Histocytochemistry; Hydrazines; Ileum; In Vitro Techniques; Indoles; Male; Methyltyrosines; Microscopy, Fluorescence; Monoamine Oxidase Inhibitors; Myenteric Plexus; Norepinephrine; Reserpine; Serotonin; Tranylcypromine | 1971 |
The role of pharmacologically-active amines in resistance to Trichostrongylus colubriformis in the guinea-pig.
Topics: 5-Hydroxytryptophan; Animals; Basophils; Eosinophils; Feces; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histidine; Hydrazines; Immunity; Immunization; Lymph Nodes; Lymphocytes; Methyldopa; Methysergide; Parasite Egg Count; Promethazine; Pyrroles; Reserpine; Serotonin; Transplantation, Homologous; Trichostrongyloidiasis; Tryptophan | 1971 |
Actions of 5-hydroxytryptamine and 5-hydroxytryptophan injected by various routes on the rectal temperature of the rabbit.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Cerebral Ventricles; Cisterna Magna; Creatinine; Hydrazines; Hydroxyindoleacetic Acid; Male; Punctures; Rabbits; Serotonin | 1972 |
Behavioral, biochemical, and histochemical analyses of the central effects of monoamine precursors after peripheral decarboxylase inhibition.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Hydrazines; Locomotion; Male; Microscopy, Fluorescence; Motor Activity; Neurotransmitter Agents; Nialamide; Norepinephrine; Rats; Reserpine; Serotonin | 1972 |
Uptake and storage mechanism of 5-hydroxytryptamine in rabbit brain stem and effect of reserpine.
Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Female; Hydrazines; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Rabbits; Reserpine; Serotonin; Stimulation, Chemical; Subcellular Fractions; Temperature | 1971 |
Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Carboxy-Lyases; Catecholamines; Dihydroxyphenylalanine; Hydrazines; Hydroxylation; Male; Methyltyrosines; Mixed Function Oxygenases; Rats; Time Factors; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1972 |
Central and peripheral effects of 5-hydroxytryptophan on motor activity in mice.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Carboxy-Lyases; Dopamine; Drug Antagonism; Drug Synergism; Hydrazines; Male; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Propionates; Serotonin | 1972 |
L- -methyl- -hydrazino- -(3,4-dihydroxyphenyl)propionic acid: relative lack of antidecarboxylase activity in adrenals.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carboxy-Lyases; Catechols; Female; Hydrazines; Kidney; Methyldopa; Pargyline; Propionates; Rats; Serotonin; Time Factors | 1972 |
Behavior and biochemical effects of preferentially protecting monoamines in the brain against the action of reserpine.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benzyl Compounds; Brain Chemistry; Catecholamines; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Hydrazines; Male; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Reserpine; Serine; Serotonin; Tetrabenazine | 1972 |
Central 5-HTP decarboxylase inhibiting properties of Ro 4-4602 in relation to 5-HTP potentiation in mice.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Dibenzazepines; Drug Synergism; Hydrazines; Male; Mice; Mice, Inbred Strains; Motor Activity; Serine; Serotonin | 1972 |
Uptake and utilization of ( 3 H-)5-hydroxytryptophan by brain tissue during development.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Carboxy-Lyases; Diencephalon; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Methyldopa; Rats; Serotonin; Telencephalon; Tritium | 1972 |
Inhibition of dopa decarboxylation by RO4-4602, MK 485 and MK 486 in human liver homogenates.
Topics: 5-Hydroxytryptophan; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Binding Sites; Carbon Isotopes; Copper; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Humans; Hydrazines; In Vitro Techniques; Kinetics; Liver; Methyldopa; Serine | 1972 |
Release of ( 3 H)dopamine by L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Hydrazines; Male; Methyldopa; Rats; Serotonin; Synaptic Vesicles; Tritium | 1972 |
5-Hydroxytryptophan reversal of reserpine enhancement of audiogenic seizure susceptibility in mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Brain Chemistry; Dopamine; Female; Hydrazines; Male; Mice; Mice, Inbred DBA; Norepinephrine; Reserpine; Seizures; Serotonin; Stimulation, Chemical | 1973 |
The action L-dopa on sexual behaviour of male rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Catecholamines; Dihydroxyphenylalanine; Hydrazines; Male; Rats; Serotonin; Sexual Behavior, Animal | 1973 |
Brain tryptophan hydroxylation: dependence on arterial oxygen tension.
Topics: 5-Hydroxytryptophan; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzyl Compounds; Brain; Brain Chemistry; Carbon Dioxide; Femoral Artery; Hydrazines; Hydrogen-Ion Concentration; Hypoxia; Lactates; Male; Mixed Function Oxygenases; Oxygen; Phosphocreatine; Pyruvates; Rats; Tryptophan Hydroxylase | 1973 |
Monoamine precursors and copulatory behavior in the male rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbidopa; Carboxy-Lyases; Castration; Copulation; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ejaculation; Female; Hydrazines; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nialamide; Pargyline; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone; Time Factors | 1973 |
Effects of 5-hydroxytryptophane on self-stimulation in rats.
Topics: 5-Hydroxytryptophan; Animals; Brain; Caudate Nucleus; Cerebral Cortex; Diencephalon; Dose-Response Relationship, Drug; Electrodes, Implanted; Glutamates; Glycine; Hydrazines; Hypothalamus; Injections, Intraperitoneal; Male; Medulla Oblongata; Mesencephalon; Myocardium; Norepinephrine; Pons; Rats; Self Stimulation; Serotonin | 1974 |
Action of probenecid on the central nervous system of the rabbit. II. Potentiation of 5-hydroxytryptophan-induced hyperthermia and suppression of this effect by a decarboxylase inhibitor (Ro4-4602).
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Body Temperature; Brain Chemistry; Brain Stem; Drug Synergism; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus; Male; Probenecid; Rabbits; Serotonin | 1974 |
Effect of a decarboxylase inhibitor (Ro 4-4602) on 5-HTP induced muricide blockade in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Dose-Response Relationship, Drug; Humans; Hydrazines; Injections, Intraperitoneal; Male; Mice; Rats; Time Factors | 1974 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. II. The central nervous system.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Depression, Chemical; Diencephalon; Dihydroxyphenylalanine; Dopamine; Electroshock; Humans; Hydrazines; Hypercapnia; Hypoxia; Limbic System; Male; Methyltyrosines; Norepinephrine; Rats; Stress, Psychological; Telencephalon | 1974 |
Effects of a decarboxylase inhibitor on the Dopa and 5-HTP induced changes in the locomotor-like discharge pattern of rabbit hind limb nerves.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Dihydroxyphenylalanine; Dopamine; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Hindlimb; Hydrazines; Locomotion; Male; Neurophysiology; Norepinephrine; Rabbits; Serotonin | 1974 |
Effect of L-DOPA and analogues on central dopamine and noradrenaline mechanisms.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Methyldopa; Methyltyrosines; Movement; Nialamide; Norepinephrine; Octopamine; Rats; Receptors, Drug; Reflex; Reserpine; Spinal Cord; Stimulation, Chemical; Tyramine; Tyrosine | 1974 |
Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Dihydroxyphenylalanine; Dioxoles; Drug Interactions; Electroencephalography; Haloperidol; Haplorhini; Humans; Hydrazines; Hyperkinesis; Injections, Intraperitoneal; Methyldopa; Methyltyrosines; Picolinic Acids; Piperazines; Pyrimidines; Tremor | 1973 |
Changes in gastric secretion induced by certain amines, amine precursors and related enzyme inhibitors.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Female; Gastric Juice; Gastrins; Hexosamines; Histamine; Histidine; Hydrazines; Hydroxyindoleacetic Acid; Indoles; Monoamine Oxidase Inhibitors; Pargyline; Pepsin A; Radiometry; Rats; Serotonin; Tritium | 1967 |
[Differential action of 2,3,4-trihydroxybenzylhydrazine on amino acid decarboxylases].
Topics: 5-Hydroxytryptophan; Animals; Aspartate Aminotransferases; Brain; Carboxy-Lyases; Dopa Decarboxylase; Escherichia coli; Glutamates; Hydrazines; Kidney; Pyridoxal Phosphate; Rabbits; Tryptophan; Tyrosine | 1967 |
Radioisotopic studies of the binding, exchange, and distribution of 5-hydroxytryptamine synthesized from its radioactive precursor.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Duodenum; Hemoglobins; Hydrazines; Kidney; Liver; Lung; Mice; Monoamine Oxidase; Myocardium; Pancreas; Radiometry; Reserpine; Serotonin; Spleen; Stomach; Tryptamines | 1966 |
[The influence of various psychopharmacologic agents on the phenelzine-induced increase of gamma-aminobutyric acid in the rat brain].
Topics: 5-Hydroxytryptophan; Amines; Aminobutyrates; Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Hormones; Hydrazines; Imidazoles; Imipramine; Methamphetamine; Monoamine Oxidase Inhibitors; Phenethylamines; Phenylhydrazines; Pyridines; Rats; Tranquilizing Agents | 1967 |
Effects of drugs on the metabolism of tryptophan. Alpha-hydrazinotryptophan and other amino acid analogs.
Topics: 5-Hydroxytryptophan; Adrenalectomy; Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Depression, Chemical; Hydrazines; Oxidation-Reduction; Rats; Serotonin; Stereoisomerism; Time Factors; Tryptamines; Tryptophan; Tryptophan Oxygenase | 1968 |
[Studies on a biological radiation protection. 85. On the effect of 5-hydroxytryptophan in the whole-body irradiation of mice].
Topics: 5-Hydroxytryptophan; Animals; Carboxy-Lyases; Hydrazines; Liver; Male; Mice; Radiation Injuries, Experimental; Radiation Protection; Radiation-Protective Agents; Radiometry; Time Factors | 1968 |
Antihypertensive and noradrenaline-depleting effects of alpha-methyl-5-hydroxytryptophan in the rat.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain Stem; Female; Hydrazines; Hypertension; Methyltyrosines; Myocardium; Norepinephrine; Rats; Serotonin; Spleen | 1969 |
Cerebrospinal fluid monoamine metabolites and peripheral decarboxylase inhibitors in parkinsonism.
Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates | 1970 |
Relative penetration of L-dopa and 5-HTP through the brain barrier using dimethyl sulfoxide.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Dihydroxyphenylalanine; Dimethyl Sulfoxide; Histocytochemistry; Hydrazines; Hypothalamus; Male; Microscopy, Fluorescence; Nialamide; Rats; Stereoisomerism | 1970 |
Formation of monoamines from various amino acids in the brain after inhibition of extracerebral decarboxylase.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benzyl Compounds; Blood-Brain Barrier; Brain; Brain Chemistry; Capillaries; Carboxy-Lyases; Catechols; Dihydroxyphenylalanine; Dopamine; Female; Fluorometry; Histocytochemistry; Hydrazines; Male; Norepinephrine; Phenols; Rats; Serine; Serotonin | 1971 |
Monoamine synthesis and concentration in neonatal rat brain during hypercapnia and recovery.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hypercapnia; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1982 |
Decreased accumulation of brain 5-hydroxytryptophan after decarboxylase inhibition in rats treated with fenfluramine, norfenfluramine or p-chloroamphetamine.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Brain; Carboxy-Lyases; Fenfluramine; Hydrazines; Male; Norfenfluramine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1983 |
Serotoninergic development in the postnatal rat brain.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Benzyl Alcohols; Brain; Clomipramine; Hydrazines; Hydroxyindoleacetic Acid; Probenecid; Rats; Serotonin; Tryptophan | 1980 |
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middle Aged; Myoclonus | 1981 |
Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindoleacetic acid in the rat striatum.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Benzyl Alcohols; Clorgyline; Corpus Striatum; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan | 1981 |
The effects of the specific uptake inhibitor Lu 10-171 (citalopram) upon brain indoleamine stores in the maturing mouse.
Topics: 5-Hydroxytryptophan; Aging; Animals; Brain; Citalopram; Hydrazines; Hydroxyindoleacetic Acid; Mice; Propylamines; Serotonin; Serotonin Antagonists | 1982 |
Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; Carbidopa; Drug Interactions; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Protein Binding | 1982 |
Serotonin turnover in individual brain nuclei: evaluation of three methods using liquid chromatography with electrochemical detection.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, Liquid; Female; Hydrazines; Hydroxyindoleacetic Acid; Pargyline; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Caffeine injection raises brain tryptophan level, but does not stimulate the rate of serotonin synthesis in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Caffeine; Hydrazines; Hydroxyindoleacetic Acid; Indoles; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1984 |
The occurrence, synthesis and metabolism of 5-hydroxytryptamine and 5-hydroxytryptophan in the cestode Hymenolepis diminuta: a high performance liquid chromatographic study.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Hydrazines; Hydroxyindoleacetic Acid; Hymenolepis; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1984 |
[Neurochemical analysis of the mechanism of action of serotoninergic substances on avoidance behavior in situations of acute stress].
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Avoidance Learning; Cyproheptadine; Humans; Hydrazines; Male; Piperazines; Piperidines; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Stress, Psychological; Tranquilizing Agents; Zimeldine | 1984 |
Regression of cerebellar syndrome with long-term administration of 5-HTP or the combination 5-HTP-benserazide.
Topics: 5-Hydroxytryptophan; Benserazide; Cerebellar Ataxia; Dopamine; Drug Therapy, Combination; Friedreich Ataxia; Humans; Hydrazines; Olivary Nucleus; Pons; Serotonin; Syndrome | 1984 |
Estimation of the rate of tryptophan hydroxylation in vivo: a sensitive microassay in discrete rat brain nuclei.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Alcohols; Brain; Cell Nucleus; Chloral Hydrate; Fenclonine; Hydrazines; Isotope Labeling; Male; Microchemistry; Pargyline; Rats; Tissue Distribution; Tritium; Tryptophan Hydroxylase | 1980 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan | 1982 |
Effects of acute lithium administration on conditioned avoidance behavior and monoamine synthesis in rats.
Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Benzyl Alcohols; Corpus Striatum; Dihydroxyphenylalanine; Hydrazines; Limbic System; Lithium; Male; Rats; Tryptophan; Tyrosine | 1980 |
Control of behaviour and brain noradrenaline neurons by peripheral blood volume receptors.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benzyl Alcohols; Blood Pressure; Blood Volume; Brain; Dopamine; Hydrazines; Male; Neurons; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains | 1981 |
Blockade of 5-HTp reduction of ethanol drinking with the decarboxylase inhibitor, ro 4-4602.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Animals; Benserazide; Dose-Response Relationship, Drug; Hydrazines; Premedication; Rats; Rats, Inbred Strains | 1981 |
Simultaneous measurement of 5-hydroxytryptophan and L-dihydroxyphenylalanine by high-performance liquid chromatography with electrochemical detection. Measurement of serotonin and catecholamine turnover in discrete brain regions.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Alcohols; Brain; Catecholamines; Chromatography, High Pressure Liquid; Hydrazines; Kinetics; Levodopa; Male; Microchemistry; Rats; Rats, Inbred Strains; Serotonin | 1982 |
[Regression of the cerebellar syndrome under long-term administration of 5-HTP or the combination of 5-HTP and benserazide. 26 cases quantified and treated using computer methods].
Topics: 5-Hydroxytryptophan; Benserazide; Cerebellar Ataxia; Computers; Drug Therapy, Combination; Humans; Hydrazines; Kinetics; Time Factors | 1982 |
Infertility in transgenic mice overexpressing the bovine growth hormone gene: disruption of the neuroendocrine control of prolactin secretion during pregnancy.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Cattle; Domperidone; Dopamine; Female; Gene Expression; Growth Hormone; Hydrazines; Hypothalamus; Infertility, Female; Median Eminence; Mice; Mice, Transgenic; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Prolactin; Promoter Regions, Genetic | 1995 |
Effect of Bay K 8644 on the synthesis and metabolism of dopamine and 5-hydroxytryptamine in various brain areas of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Rats; Rats, Wistar; Serotonin | 1993 |
Daily variations in in vivo tryptophan hydroxylation and in the contents of serotonin and 5-hydroxyindoleacetic acid in discrete brain areas of the rat.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Brain Chemistry; Chromatography, High Pressure Liquid; Circadian Rhythm; Electrochemistry; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1993 |
Simultaneous determination of in vivo hydroxylation of tyrosine and tryptophan in rat striatum by microdialysis-HPLC: relationship between dopamine and serotonin biosynthesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1993 |
Blockade of transmission at NMDA receptors facilitates the electrical and synthetic activity of ascending serotoninergic neurones.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dizocilpine Maleate; Electrophysiology; Hydrazines; Male; Neurons; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Synaptic Transmission | 1994 |
Stimulation of brain dopamine autoreceptors by remoxipride administration in reserpine-treated male rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Haloperidol; Hydrazines; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Remoxipride; Reserpine; Stimulation, Chemical; Sulpiride | 1993 |
Differential activation of the 5-hydroxytryptamine-containing neurons of the midbrain raphe of the rat in response to randomly presented inescapable sound.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Enzyme Inhibitors; Hydrazines; Male; Neural Pathways; Neurons; Random Allocation; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Psychological | 1995 |
[Features of the antidepressive effect of O-beta-chloroethyl-para-N-dimethylaminophenylphosphinylacetic acid (amfazide)].
Topics: 5-Hydroxytryptophan; Acetates; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Hydrazines; Male; Mice; Mice, Inbred Strains; Serotonin Receptor Agonists | 1996 |
In vivo tryptophan hydroxylase activity in rat major cerebral arteries is decreased by dorsal raphe nucleus lesions.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Aorta; Aromatic Amino Acid Decarboxylase Inhibitors; Cerebral Arteries; Corpus Striatum; Electrocoagulation; Enzyme Inhibitors; Fenclonine; Hippocampus; Hydrazines; Hypothalamus; Levodopa; Male; Methyltyrosines; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Tryptophan Hydroxylase | 1996 |
Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long-term hypoxic exposure in the rat.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Enzyme Inhibitors; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Nerve Endings; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase | 1997 |
Serotonergic mechanisms involved in calcitonin potentiation of kappa-opioid receptor-mediated effects on adrenal secretion.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 5-Hydroxytryptophan; Analgesics, Non-Narcotic; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Calcitonin; Corticosterone; Enzyme Inhibitors; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamo-Hypophyseal System; Male; Monoamine Oxidase Inhibitors; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Pituitary Hormone-Regulating Hormone; Serotonin; Tranylcypromine | 1997 |
Serotonergic activity in the rat striatum after intrastriatal transplantation of fetal nigra as measured by microdialysis.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Enzyme Inhibitors; Female; Fetal Tissue Transplantation; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Microdialysis; Oxidopamine; Rats; Rats, Wistar; Serotonin; Substantia Nigra; Transplantation, Heterotopic | 1998 |
In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzopyrans; Brain Chemistry; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hydrazines; Male; Neostriatum; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Biogenic Amine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 1999 |
Differential effect of immobilization stress on in vivo synthesis rate of monoamines in medial prefrontal cortex and nucleus accumbens of conscious rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Consciousness; Dihydroxyphenylalanine; Hydrazines; Hydroxylation; Kinetics; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Restraint, Physical; Serotonin; Stress, Physiological; Tryptophan; Tyrosine | 1999 |
Melatonin and its precursors scavenge nitric oxide.
Topics: 5-Hydroxytryptophan; Cadmium; Copper; Free Radical Scavengers; Hydrazines; Indicators and Reagents; Kinetics; Melatonin; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Serotonin; Tryptophan | 1999 |
Lack of glucocorticoids attenuates the self-stimulation-induced increase in the in vivo synthesis rate of dopamine but not serotonin in the rat nucleus accumbens.
Topics: 5-Hydroxytryptophan; Adrenalectomy; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Cortisone; Dihydroxyphenylalanine; Dopamine; Enzyme Inhibitors; Glucocorticoids; Hydrazines; Hydroxylation; Male; Microdialysis; Neurons; Nucleus Accumbens; Rats; Rats, Wistar; Self Administration; Self Stimulation; Serotonin; Tryptophan; Tyrosine | 2000 |
Intracranial self-stimulation increases differentially in vivo hydroxylation of tyrosine but similarly in vivo hydroxylation of tryptophan in rat medial prefrontal cortex, nucleus accumbens and striatum.
Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Dopamine; Enzyme Inhibitors; Hydrazines; Hydroxylation; Male; Microdialysis; Microelectrodes; Neostriatum; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Reward; Self Stimulation; Serotonin; Stress, Physiological; Time Factors; Tryptophan; Tyrosine | 2000 |
Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Enzyme Inhibitors; Escherichia coli; Frontal Lobe; Hydrazines; Levodopa; Lipopolysaccharides; Male; Mesencephalon; Organ Specificity; Rats; Rats, Sprague-Dawley; Time Factors; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2000 |
Evidence for involvement of 5-hydroxytryptamine(1B) autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine.
Topics: 5-Hydroxytryptophan; Animals; Autoreceptors; Brain; Drug Interactions; Fluoxetine; Hydrazines; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Spiro Compounds | 2002 |
[Action of different inhibitors of L-DOPA 5 HTP decarboxylase on insulin hypoglycemia in the rat].
Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Antimetabolites; Cinnamates; Dopa Decarboxylase; Hydrazines; Hyperinsulinism; Hypoglycemia; Insulins; Levodopa; Rats; Seizures; Tremor | 1963 |
[COMPARATIVE ACTION OF 2 DECARBOXYLASE INHIBITORS ON THE METABOLISM OF ENDOGENOUS AND EXOGENOUS 5-HYDROXYTRYPTAMINE].
Topics: 5-Hydroxytryptophan; Antihypertensive Agents; Brain; Carboxy-Lyases; Enzyme Inhibitors; Hydrazines; Metabolism; Methyldopa; Pharmacology; Rats; Research; Serotonin | 1964 |
CORRELATION BETWEEN BRAIN CATECHOLAMINE AND SEDATIVE ACTION OF RESERPINE.
Topics: 5-Hydroxytryptophan; Brain; Catecholamines; Dihydroxyphenylalanine; Hydrazines; Hypnotics and Sedatives; Indoles; Iproniazid; Mandelic Acids; Norepinephrine; Normetanephrine; Pharmacology; Phenethylamines; Rabbits; Research; Reserpine; Sympathomimetics | 1964 |
EFFECT OF SOME BENZYLHYDRAZINES AND BENZYLOXYAMINES ON DOPA AND 5-HYDROXYTRYPTOPHAN DECARBOXYLASE IN VIVO.
Topics: 5-Hydroxytryptophan; Amines; Aromatic-L-Amino-Acid Decarboxylases; Carbon Isotopes; Carboxy-Lyases; Dihydroxyphenylalanine; Hydrazines; Hydroxylamines; Iproniazid; Metabolism; Mice; Pharmacology; Radiometry; Research; Serotonin; Tremor | 1964 |
INHIBITION OF CEREBRAL DECARBOXYLASE AND BEHAVIOUR.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Brain Chemistry; Carboxy-Lyases; Dopamine; Enzyme Inhibitors; Hydrazines; Metabolism; Methyldopa; Mice; Norepinephrine; Pharmacology; Research; Serotonin | 1964 |
Ethanol desensitizes cannabinoid CB1 receptors modulating monoamine synthesis in the rat brain in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Analysis of Variance; Animals; Benzoxazines; Biogenic Monoamines; Brain; Brain Chemistry; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Ethanol; Hydrazines; Male; Morpholines; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1 | 2006 |
Validation studies on the 5-hydroxy-L-[beta-11C]-tryptophan/PET method for probing the decarboxylase step in serotonin synthesis.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Carbon Radioisotopes; Clorgyline; Enzyme Inhibitors; Female; Hydrazines; Macaca mulatta; Positron-Emission Tomography; Serotonin | 2006 |
Effect of the beta3 adrenoceptor agonist CL 316243 on hypothalamic 5-HT synthesis and suppression of REM sleep in the rat.
Topics: 5-Hydroxytryptophan; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Dioxoles; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; Hypothalamus; Male; Rats; Receptors, Adrenergic, beta-3; Serotonin; Sleep, REM; Time Factors; Wakefulness | 2007 |
Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex.
Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Fluoxetine; Hydrazines; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Pargyline; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Time Factors; Tryptophan | 2008 |
Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corticotropin-Releasing Hormone; Hydrazines; In Vitro Techniques; Male; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Tryptophan Hydroxylase | 2009 |
Lack of differential serotonin biosynthesis capacity in genetically selected low and high aggressive mice.
Topics: 5-Hydroxytryptophan; Aggression; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hydrazines; Male; Mice; Mice, Inbred Strains; Prefrontal Cortex; Raphe Nuclei; Reaction Time; Serotonin; Species Specificity | 2009 |
A role for serotonin in the antidepressant activity of NG-Nitro-L-arginine, in the rat forced swimming test.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Brain; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fluoxetine; Hydrazines; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Male; Metergoline; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Tryptophan Hydroxylase | 2010 |
5-Hydroxytryptophan attenuates somatic signs of nicotine withdrawal.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Hydrazines; Male; Nicotine; Rats; Rats, Sprague-Dawley; Serotonin Agents; Smoking Cessation; Substance Withdrawal Syndrome | 2011 |
Effect of chronic protein ingestion on tyrosine and tryptophan levels and catecholamine and serotonin synthesis in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Caseins; Catecholamines; Cerebral Cortex; Diet, Protein-Restricted; Dietary Proteins; Dihydroxyphenylalanine; Enzyme Inhibitors; Hydrazines; Hypothalamus; Male; Protein Deficiency; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan; Tyrosine | 2011 |
On the presence of serotonin in mammalian cardiomyocytes.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Blood Platelets; Cells, Cultured; Fenclonine; Heart Atria; Humans; Hydrazines; Mice; Myocardium; Myocytes, Cardiac; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2012 |
[(11)C]5-HTP and microPET are not suitable for pharmacodynamic studies in the rodent brain.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Carbon Radioisotopes; Enzyme Inhibitors; Hydrazines; Male; Models, Biological; Positron-Emission Tomography; Rats; Rats, Wistar; Sensitivity and Specificity; Serotonin; Tissue Distribution; Tryptophan | 2014 |
Effects of 5-hydroxytryptophan and m-hydroxybenzylhydrazine associated to Lactobacillus spp. on the humoral response of broilers challenged with Salmonella Enteritidis.
Topics: 5-Hydroxytryptophan; Animals; Cecum; Chickens; Colony Count, Microbial; Diet; Dietary Supplements; Hydrazines; Immunity, Humoral; Lactobacillus; Male; Poultry Diseases; Probiotics; Random Allocation; Salmonella enteritidis; Salmonella Infections, Animal; Serotonin Antagonists | 2015 |