5-hydroxytryptophan and carbidopa

5-hydroxytryptophan has been researched along with carbidopa in 166 studies

Research

Studies (166)

TimeframeStudies, this research(%)All Research%
pre-1990126 (75.90)18.7374
1990's15 (9.04)18.2507
2000's12 (7.23)29.6817
2010's11 (6.63)24.3611
2020's2 (1.20)2.80

Authors

AuthorsStudies
Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ1
Quik, M; Sourkes, TL1
Butler, IJ; Koslow, SH1
Rubin, W; Schwartz, B3
Chadwick, D; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH1
Bartholomé, K; Byrd, DJ1
Anderson, DR; Guy, J; Quigley, HA1
Lown, B; Rabinowitz, SH1
Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA1
Boggan, WO; Buckholtz, NS; Meyer, JS1
Levin, SL1
de Fine Olivarius, B; Dupont, E; Magnussen, I; Prange-Hansen, A1
Borden, M; Kaufman, I; Kulovich, S; Nyhan, WL; Sweetman, L1
Deshmukh, VD; Haufrect, DB; Jacob, RH; Mathew, NT; Meyer, JS; Morrell, RM; Perez, FI; Welch, KM1
Gale, CC; Garcia, JF; Mixter, RC; Ruch, W; Russell, RM1
Fahn, S1
de Fine Olivarius, B; Dupont, E; Engbaek, F; Magnussen, I1
Becker, L; Hurwic, MJ; Kupietz, SS; Sverd, J; Winsberg, BG1
Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD1
Engbaek, F; Magnussen, I1
Appel, JB; Carter, RB; Dykstra, LA; Leander, JD1
Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG1
Connors, MH; Dorsa, DM1
Fozard, JR; Palfreyman, MG1
Rosenbaum, D; Van Woert, MH1
Blundell, JE; Latham, CJ1
Hjälmås, K; Rubenson, A; Sillén, U1
Barchas, JD; Berger, PA; Brodie, KH; Sack, R; Zarcone, VP1
Bigelow, LB; Gillin, JC; Walls, P; Wyatt, RJ1
Bowers, MB; Howieson, J; Rosenbaum, D; Van Woert, MH1
Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH1
Gillin, JC; Magyar, RL; Wyatt, RJ1
Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH1
Sethy, VH; Van Woert, MH2
Stancer, HC; Warsh, JJ2
De Léan, J; Hornykiewicz, O; Richardson, JC1
Nyhan, WL1
Growdon, JH; Shahani, BT; Young, RR1
Anderson, LT; Dancis, J; Herrmann, L1
Engel, J; Katzman, R; Sharpless, N; Thal, L; Wolfson, L1
Eckardt, MJ; George, DT; Lindquist, T; Linnoila, M; Martin, PR; Mathis, C; Moss, H; Rawlings, RR1
Brammer, NT; Charlett, A; Doré, CJ; Fletcher, A; Hudson, S; Minchin, MC; Wann, KT; Wardley-Smith, B1
Joly, P; Lampert, A; Lauret, P; Thomine, E1
Bhatt, M; Calne, D; Snow, B; Varelas, M1
Fukuyama, Y; Hayakawa, T; Nakano, K; Ohsawa, M; Shishikura, K; Suzuki, H1
Koshikawa, F; Koshikawa, N; Stephenson, JD2
Löscher, W; Pagliusi, SR1
Alper, RH; Fagin, KD; Johnston, CA; Negro-Vilar, A1
López-Ibor, JJ; Pérez de los Cobos, JC; Saiz-Ruiz, J1
Chung, EY; Rosenbaum, D; Van Woert, MH1
De Léan, J; Rewcastle, NB; Richardson, JC1
Jenner, P; Luscombe, G; Marsden, CD2
Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A1
Lehnert, H; Lombardi, F; Lorenzo, AV; Lown, B; Raeder, EA; Verrier, RL; Wurtman, RJ1
Clementi, RA; Ferguson, RK; Rotmensch, HH; Swanson, BN; Vlasses, PH1
Goodrich, C; Lechner, R; Slone, W1
Diamond, B; Fahn, S; Mena, MA; Pezzoli, G; Truong, DD1
Ding, XR; Itskovitz, HD; Stier, CT1
Brewer, TF; Itskovitz, HD; Sheridan, AM; Stier, CT; Werber, JL1
Handley, SL; Singh, L1
Butler, IJ; Irons, M; Kaufman, S; Langlais, PJ; Levy, HL; Milstien, S; O'Flynn, ME; Stack, CV1
Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G1
De Souza, RJ; Goodwin, GM; Green, AR; Wood, AJ1
Magnussen, I2
Pulmones, MT; Sansaricq, C; Snyderman, SE1
Byerley, WF; Grosser, BI; Judd, LL; Reimherr, FW1
Carvey, PM; Goetz, CG; Klawans, HL; Tanner, CM1
Chamson, A; Frey, J; Périer, C1
Peters, DA1
Endo, Y2
Fujii, T; Taguchi, H1
Eble, JP; Goodrich, C1
Carlsson, L; Elg, R; Hallberg, H1
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A1
Itskovitz, HD; Stier, CT1
Dijken, WA; Kamp, JS; Nolen, WA; van de Putte, JJ1
Chase, TN1
Antonaccio, MJ; Robson, RD1
Porter, CC; Stone, CA; Torchiana, ML1
Modigh, K2
Malmnäs, CO1
Löscher, W; Müller, F; Pagliusi, SR1
Frohman, CE; Hryhorczuk, LM; McIntyre, IM; Novak, EA; Oxenkrug, GF1
Berge, OG1
Hanley, WB; Kapatos, G; Kaufman, S; MacGregor, D; McInnes, RR; Milstien, S; Soldin, S; Van Loon, GR; Walsh, P; Warsh, JJ1
Jensen, TS; Magnussen, I; Rand, JH; Van Woert, MH1
Hwang, EC; Lowe, YH; Magnussen, I; Van Woert, MH1
Magnussen, I; Van Woert, MH1
Gerritsen, TW; Meijer, BA; van Praag, HM; Westenberg, HG1
Chung, E; Magnussen, I; Rosenbaum, D; Van Woert, MH1
Bell, MJ; Fam, AG; Rush, PJ1
Bodhankar, S; Osuide, G; Wambebe, C1
Ganong, WF; Kaplan, SL; Zimmermann, H1
Lalley, PM; McCrimmon, DR1
Van Woert, MH1
Herbert, J; Martensz, ND1
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS1
Hiramatsu, M1
Coen, CW; Franklin, M; Laynes, RW; MacKinnon, PC1
Carlini, EA; Santos, R1
Grahame-Smith, DG; Green, AR; Hammond, M; O'Shaughnessy, K; Schächter, M1
Johnels, B1
Itskovitz, HD; McKendall, G; Stier, CT1
Clarke, KA; Parker, AJ; Stirk, GC1
Curtius, HC; Endres, W; Niederwieser, A; Ohrt, B; Schaub, J; Wang, M1
Aubert, ML; Ganong, WF; Grumbach, MM; Holland, FJ; Kaplan, SL; Richards, GE1
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN1
Dunner, FJ; McCalley-Whitters, M; Nasrallah, HA; Smith, RE1
Magnussen, I; Nielsen-Kudsk, F1
van Hiele, LJ1
Carter, RB; Leander, JD1
Katzman, R; Sharpless, NS; Thal, LJ; Wolfson, L1
Fine, RM1
Barney, CC; Fregly, MJ; Greenleaf, JE; Kikta, DC; Threatte, RM1
Grota, LJ1
Echizen, H; Freed, CR1
Johnson, HG; Jones, KL; Kaufman, IA; Nyhan, WL1
Avanzini, G; Franceschetti, S; Lombardi, B; Passerini, A1
Hedner, T; Lundborg, P1
Obach, R; Pruñonosa, J; Vallés, J; Vallés, JM1
Ganong, WF; Zimmermann, H1
Baker, H; Gauthier, S; Magnussen, I; Osterland, CK; Sternberg, EM; Van Woert, MH; Young, SN1
Lima, L; Urbina, M1
Ciccocioppo, R; Gessa, GL; Massi, M; Panocka, I; Stefanini, E1
Ashwal, S; Bodensteiner, J; Franz, D; Haas, RH; Huang, Y; Pranzatelli, MR; Tate, E1
Gordon, EA; Hudgel, DW; Meltzer, HY1
Dick, H; Fink, G; Goodwin, GM; Young, AH1
Blau, N; Dhondt, JL1
Gudelsky, GA; Nash, JF1
Gordon, EA; Hudgel, DW1
Cabezas-Cerrato, J; Graña, M; Lado-Abeal, J; Rey, C1
Abeling, N; Bergmann, C; Blau, N; Häring, M; Häusler, M; Heimann, G; Ramaekers, VT; Senderek, J; Zerres, K1
Borri-Voltattorni, C; Burkhard, P; Dominici, P; Jansonius, JN; Malashkevich, VN1
Cohen, AF; de Kam, ML; de Rijk, R; Gijsman, HJ; Pieters, MS; Schoemaker, RC; van der Post, J; van Gerven, JM; Weemaes, M1
Darmani, NA; Johnson, JC1
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ1
Bergström, M; Eriksson, B; Långström, B; Lu, L; Oberg, K; Orlefors, H; Sundin, A1
Assmann, B; Blau, N; Echenne, B; Hoffmann, GF; Lutz, T; Penzien, JM; Roubertie, A; Thöny, B1
Garske, U; Orlefors, H; Sundin, A1
de Kam, ML; de Rijk, R; Gijsman, HJ; Hoeberechts-Lefrandt, DH; Jacobs, GE; Schoemaker, RC; Smarius, LJ; van der Post, JP; van Gerven, JM; van Pelt, J; Zitman, FG1
Concolino, D; Moricca, MT; Muzzi, G; Pascale, MG; Rapsomaniki, M; Strisciuglio, P1
de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG1
Greenway, FL; Hendricks, EJ; Rothman, RB1
Dugan, EA; Hayashi, Y; Jacob-Vadakot, S; McBride, S; Murray, M; Olexa, R; Shumsky, JS; Simansky, K1
Cohen, AF; de Kam, ML; der Grond, Jv; Jacobs, GE; Langeveld, TJ; Teeuwisse, WM; van Gerven, JM; van Pelt, J; Verhagen, JC; Zitman, FG1
Popper, CW1
de Vries, EF; Di Gialleonardo, V; Dierckx, RA; Kema, IP; Ramakrishnan, NK; van Waarde, A; Visser, AK; Willemsen, AT1
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D1
Anastasia, A; Carli, M; Invernizzi, RW; Kostoula, C; Mainolfi, P; Sacchetti, G; Villani, C1
Azam, A; Azam, B; Jensen, DB; Wienecke, J; Zhang, M1
Friedman, JR1
Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R1
Bartel, T; Blydt-Hansen, I; Connolly, MB; Horvath, GA; Race, S; Ross, CJ; Tarailo-Graovac, M; Van Allen, MI; van Karnebeek, CDM; Wasserman, WW1
Flores-Murrieta, FJ; Huerta-Cruz, JC; Lara-Padilla, E; Limón-Bernal, E; Reyes-García, JG; Roa-Coria, JE; Rocha-González, HI; Ruíz-Velasco, IRC; Zúñiga-Romero, Á1
Hale, MW; Kent, S; Lesku, JA; Lowry, CA; Payet, JM; Russo, AM1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Reviews

5 review(s) available for 5-hydroxytryptophan and carbidopa

ArticleYear
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception

1976
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans

1987
Serotonergic mechanisms and extrapyramidal function in man.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors

1974
Nuclear imaging of neuroendocrine tumours.
    Best practice & research. Clinical endocrinology & metabolism, 2007, Volume: 21, Issue:1

    Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Carbidopa; Glucose-6-Phosphate; Humans; Levodopa; Neuroendocrine Tumors; Positron-Emission Tomography; Receptors, Somatostatin; Somatostatin

2007
Mood disorders in youth: exercise, light therapy, and pharmacologic complementary and integrative approaches.
    Child and adolescent psychiatric clinics of North America, 2013, Volume: 22, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Antidepressive Agents, Second-Generation; Carbidopa; Child; Complementary Therapies; Depressive Disorder, Major; Enzyme Inhibitors; Exercise Therapy; Humans; Hypericum; Integrative Medicine; Mood Disorders; Phototherapy; Phytotherapy; S-Adenosylmethionine; Treatment Outcome

2013

Trials

22 trial(s) available for 5-hydroxytryptophan and carbidopa

ArticleYear
Effects of L-5-hydroxytryptophan in autistic children.
    Journal of autism and childhood schizophrenia, 1978, Volume: 8, Issue:2

    Topics: 5-Hydroxytryptophan; Attention; Autistic Disorder; Brain; Carbidopa; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Serotonin; Social Adjustment; Verbal Behavior

1978
The indoleamine hypothesis of depression: an overview and pilot study.
    Diseases of the nervous system, 1977, Volume: 38, Issue:8

    Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydroxycorticosteroids; Hydroxyindoleacetic Acid; Male; Middle Aged; Models, Neurological; Serotonin

1977
Clinical effects of L-5-hydroxytryptophan administration in chronic schizophrenic patients.
    Biological psychiatry, 1979, Volume: 14, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia

1979
Serotonin and myoclonus.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoles; Male; Middle Aged; Myoclonus; Serotonin

1976
The effect of L-5-hydroxytryptophan on self-mutilatin in Lesch-Nyhan disease: a negative report.
    Neuropadiatrie, 1976, Volume: 7, Issue:4

    Topics: 5-Hydroxytryptophan; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Lesch-Nyhan Syndrome; Male; Self Mutilation

1976
Pharmacologic maintenance of abstinence in patients with alcoholism: no efficacy of 5-hydroxytryptophan or levodopa.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:5

    Topics: 5-Hydroxytryptophan; Adult; Alcoholism; Analysis of Variance; Carbidopa; Double-Blind Method; Drug Therapy, Combination; Educational Status; Female; Humans; Intelligence Tests; Levodopa; Male; Memory; Middle Aged; Neuropsychological Tests; Time Factors

1992
Effect of repeated doses of L-5-hydroxytryptophan and carbidopa on prolactin and aldosterone secretion in man.
    Journal of endocrinological investigation, 1989, Volume: 12, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aldosterone; Carbidopa; Dexamethasone; Humans; Hydroxyindoleacetic Acid; Male; Natriuresis; Prolactin

1989
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans

1987
L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Drug Resistance; Drug Therapy, Combination; Fluvoxamine; Follow-Up Studies; Humans; Maprotiline; Middle Aged; Oximes; Random Allocation; Serotonin Antagonists; Stereoisomerism; Tranylcypromine

1985
Myoclonus and L-5-hydroxytryptophan (L-5HTP).
    Progress in clinical and biological research, 1983, Volume: 127

    Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Drug Industry; Drug Therapy, Combination; Humans; Legislation, Drug; Myoclonus; United States

1983
Atypical phenylketonuria due to biopterin deficiency. Early treatment with tetrahydrobiopterin and neurotransmitter precursors, trials of monotherapy.
    Helvetica paediatrica acta, 1982, Volume: 37, Issue:5

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Clinical Trials as Topic; Humans; Infant; Levodopa; Male; Phenylketonurias; Pteridines

1982
Serotonin precursor effects in tardive dyskinesia.
    Psychopharmacology, 1982, Volume: 77, Issue:3

    Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Serotonin

1982
Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.
    The New England journal of medicine, 1980, Oct-02, Volume: 303, Issue:14

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kynurenine; Levodopa; Male; Middle Aged; Myoclonus; Parkinson Disease; Scleroderma, Systemic; Serotonin

1980
Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan.
    Epilepsia, 1995, Volume: 36, Issue:8

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid; Male; Mitochondrial Encephalomyopathies; Pilot Projects; Serotonin

1995
Serotonin-induced cortisol release in CPAP-treated obstructive sleep apnea patients.
    Chest, 1997, Volume: 111, Issue:3

    Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Enzyme Inhibitors; Female; Humans; Hydrocortisone; Male; Middle Aged; Positive-Pressure Respiration; Radioimmunoassay; Serotonin; Sleep Apnea Syndromes

1997
L-5-hydroxytryptophan does not stimulate LH secretion directly from the pituitary in patients with gonadotrophin releasing hormone deficiency.
    Clinical endocrinology, 1998, Volume: 49, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Hypothalamic Diseases; Hypothalamus; Luteinizing Hormone; Male; Pituitary Gland; Secretory Rate

1998
A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa.
    Molecular genetics and metabolism, 2001, Volume: 73, Issue:2

    Topics: 5-Hydroxytryptophan; Abnormalities, Multiple; Carbidopa; Child; Child, Preschool; Developmental Disabilities; DNA; DNA Mutational Analysis; Drug Therapy, Combination; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Learning Disabilities; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Syndrome; Tetrahydrofolates; Treatment Outcome; Tryptophan Hydroxylase

2001
Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Adverse Drug Reaction Reporting Systems; Carbidopa; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Prolactin; Receptors, Presynaptic; Receptors, Serotonin

2002
Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Carbidopa; Carbon Radioisotopes; Carcinoid Tumor; Female; Humans; Image Enhancement; Liver Neoplasms; Lymphatic Metastasis; Male; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2006
Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
    Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:4

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adrenocorticotropic Hormone; Adult; Affect; Antidepressive Agents, Second-Generation; Biological Availability; Brain; Carbidopa; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Half-Life; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Nausea; Patient Dropouts; Prolactin; Vomiting; Young Adult

2008
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area Under Curve; Carbidopa; Cross-Over Studies; Domperidone; Dopamine Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Granisetron; Humans; Hydrocortisone; Male; Nausea; Prolactin; Vomiting; Young Adult

2010
Hypothalamic glutamate levels following serotonergic stimulation: a pilot study using 7-Tesla magnetic resonance spectroscopy in healthy volunteers.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Apr-16, Volume: 34, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Adult; Aspartic Acid; Carbidopa; Choline; Dopamine Agents; Double-Blind Method; Glutamic Acid; Glutamine; Granisetron; Humans; Hypothalamus; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Serotonin Agents; Time Factors; Young Adult

2010

Other Studies

140 other study(ies) available for 5-hydroxytryptophan and carbidopa

ArticleYear
Central dopaminergic and serotoninergic systems in the regulation of adrenal tyrosine hydroxylase.
    Journal of neurochemistry, 1977, Volume: 28, Issue:1

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Adrenal Glands; Animals; Apomorphine; Bromocriptine; Carbidopa; Clonidine; Dopamine; Drug Interactions; Haloperidol; Hydroxydopamines; Injections, Intraventricular; Kinetics; Levodopa; Male; Piribedil; Pituitary Gland; Rats; Serotonin; Serotonin Antagonists; Splanchnic Nerves; Tyrosine 3-Monooxygenase

1977
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
    Science (New York, N.Y.), 1977, Nov-04, Volume: 198, Issue:4316

    Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine

1977
An electron microscopic radioautographic identification of the "enterochromaffin-like" APUD cells in murine oxyntic glands. Demonstration of a metabolic difference between rat and mouse gastric A-like cells.
    Gastroenterology, 1979, Volume: 76, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; APUD Cells; Aromatic Amino Acid Decarboxylase Inhibitors; Autoradiography; Carbidopa; Chromaffin System; Dopa Decarboxylase; Enterochromaffin Cells; Gastric Mucosa; Histamine; Male; Mice; Microscopy, Electron; Rats; Serotonin

1979
Manipulation of brain serotonin in the treatment of myoclonus.
    Lancet (London, England), 1975, Sep-06, Volume: 2, Issue:7932

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Benzodiazepinones; Brain; Carbidopa; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Infusions, Parenteral; Male; Middle Aged; Myoclonus; Serotonin

1975
Letter: L-dopa and 5-hydroxytryptophan therapy in phenylketonuria with normal phenylalanine-hydroxylase activity.
    Lancet (London, England), 1975, Nov-22, Volume: 2, Issue:7943

    Topics: 5-Hydroxytryptophan; Carbidopa; Drug Therapy, Combination; Humans; Infant; Levodopa; Phenylalanine Hydroxylase; Phenylketonurias

1975
The effect of biogenic monomines on rapid axonal transport in the rabbit optic nerve.
    Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Axonal Transport; Biogenic Amines; Carbidopa; Female; Levodopa; Male; Optic Nerve; Pargyline; Rabbits; Time Factors

1978
Central neurochemical factors related to serotonin metabolism and cardiac ventricular vulnerability for repetitive electrical activity.
    The American journal of cardiology, 1978, Volume: 41, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Dogs; Female; Heart Rate; Heart Ventricles; Male; Phenelzine; Serotonin; Sympathetic Nervous System; Tryptophan; Ventricular Fibrillation

1978
Fenfluramine-induced enhancement of confinement motor activity: an indirect 5-hydroxytryptamine-like action?
    Neuropharmacology, 1975, Volume: 14, Issue:4

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Brain Chemistry; Carbidopa; Catecholamines; Cinanserin; Female; Fenclonine; Fenfluramine; Metergoline; Methylphenidate; Motor Activity; Rats

1975
Serotonergic stimulation of pituitary-adrenal activity in the mouse.
    Neuroendocrinology, 1978, Volume: 26, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Carbidopa; Carbolines; Corticosterone; Cyproheptadine; Female; Fenclonine; Indoles; Metergoline; Mice; Pargyline; Phenyl Ethers; Pituitary-Adrenal System; Propylamines; Quinolines; Quipazine; Spiperone; Tryptophan

1978
[Serotoninergic conception of myoclonic syndromes. (Review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dogs; Electroencephalography; Electromyography; Guinea Pigs; Humans; Hydroxyindoleacetic Acid; Myoclonus; Raphe Nuclei; Reticular Formation; Serotonin; Spinal Cord; Synaptic Transmission

1979
Palatal myoclonus treated with 5-hydroxytryptophan and a decarboxylase-inhibitor.
    Acta neurologica Scandinavica, 1977, Volume: 55, Issue:3

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Combinations; Humans; Hydrazines; Male; Muscle Contraction; Myoclonus; Palate

1977
Altered excreton of 5-hydroxyindoleacetic acid and glycine in patients with the Lesch-Nyhan disease.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: 5-Hydroxytryptophan; Adolescent; Carbidopa; Child; Child, Preschool; Glycine; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syndrome

1977
Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease.
    Journal of the American Geriatrics Society, 1977, Volume: 25, Issue:7

    Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurocognitive Disorders; Probenecid; Serotonin; Tyrosine

1977
Aminergic and thermoregulatory mechanims in hypothalamic regulation of growth hormone in cats.
    The American journal of physiology, 1977, Volume: 233, Issue:1

    Topics: 18-Hydroxycorticosterone; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Amines; Blood Glucose; Body Temperature Regulation; Carbidopa; Cats; Growth Hormone; Hypothalamus; Levodopa; Male; Mesencephalon; Norepinephrine; Phenoxybenzamine; Pimozide; Serotonin; Temperature

1977
New approaches in the management of hyperkinetic movement disorders.
    Advances in experimental medicine and biology, 1977, Volume: 90

    Topics: 5-Hydroxytryptophan; Carbidopa; Chorea; Dyskinesia, Drug-Induced; Humans; Movement Disorders; Myoclonus; Propranolol; Receptors, Dopamine; Torticollis; Tranquilizing Agents; Tremor

1977
Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor.
    Acta neurologica Scandinavica, 1978, Volume: 57, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Hypoxia; Male; Myoclonus

1978
Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
    Neuropadiatrie, 1978, Volume: 9, Issue:2

    Topics: 5-Hydroxytryptophan; Carbidopa; Child; Drug Therapy, Combination; Humans; Hydrazines; Lesch-Nyhan Syndrome; Male; Movement Disorders; Self Mutilation; Sleep; Wakefulness

1978
The effects of aromatic amino acid decarboxylase inhibitors on plasma concentrations of 5-hydroxytryptophan in man.
    Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Female; Humans; Kinetics; Male; Middle Aged; Time Factors

1978
Role of peripheral mechanisms in the behavioral effects of 5-hydroxytryptophan.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benserazide; Carbidopa; Male; Proglumide; Rats; Reinforcement Schedule

1978
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
    Journal of autism and developmental disorders, 1979, Volume: 9, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Self Mutilation; Serotonin

1979
Canine growth hormone responsiveness during pentobarbital anesthesia: a method for evaluating serotoninergic stimulatory action.
    Endocrinology, 1979, Volume: 104, Issue:1

    Topics: 5-Hydroxytryptophan; Adrenal Cortex Hormones; Animals; Carbidopa; Dogs; Female; Growth Hormone; Hypoglycemia; Hypothalamus; Insulin; Pentobarbital

1979
Metoclopramide antagonism of 5-hydroxytryptophan-induced "wet-dog" shake behaviour in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Carbidopa; Haloperidol; Male; Methysergide; Metoclopramide; Quipazine; Rats; Serotonin; Time Factors

1979
L-5-hydroxytryptophan therapy in myoclonus.
    Advances in neurology, 1979, Volume: 26

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clomipramine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myoclonus

1979
Serotonergic influences on food intake: effect of 5-hydroxytryptophan on parameters of feeding behaviour in deprived and free-feeding rats.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Food Deprivation; Male; Rats; Serotonin; Time Factors

1979
Evidence for a central monoaminergic influence on urinary bladder control mechanism.
    Scandinavian journal of urology and nephrology, 1979, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Carbidopa; Catecholamines; Dopamine; Levodopa; Male; Norepinephrine; Parasympathetic Nervous System; Pressure; Rats; Spiperone; Urinary Bladder; Urodynamics

1979
Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa.
    The New England journal of medicine, 1977, Jan-13, Volume: 296, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbidopa; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydrazines; Hypoxia, Brain; Long-Term Care; Male; Middle Aged; Myoclonus; Serotonin; Tryptophan

1977
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
    Brain : a journal of neurology, 1977, Volume: 100, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsy, Post-Traumatic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Isocarboxazid; Male; Methysergide; Middle Aged; Myoclonus; Premedication; Tryptophan

1977
Tolerance to the increased locomotor activity produced by L-5-hydroxytryptophan following peripheral decarboxylase inhibition in mice.
    Psychopharmacology, 1978, Apr-11, Volume: 56, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Drug Tolerance; Hydrazines; Male; Mice; Motor Activity; Time Factors

1978
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
    Neurology, 1975, Volume: 25, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin

1975
The origin of blood k-hydroxyindoleacetic acid following L-hydrazino-alpha-methyldopa (MK-486).
    European journal of pharmacology, 1975, Volume: 32, Issue:1

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin

1975
The origin of blood 5-hydroxyindoleacetic acid following L-hydrazine-alpha-methyldopa (MK-486).
    European journal of pharmacology, 1975, Volume: 32, Issue:1

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin

1975
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
    Neurology, 1976, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; Male; Methysergide; Middle Aged; Myoclonus; Serotonin; Syndrome; Tryptophan

1976
Behavior in the Lesch--Nyhan syndrome.
    Journal of autism and childhood schizophrenia, 1976, Volume: 6, Issue:3

    Topics: 5-Hydroxytryptophan; Aggression; Behavior Therapy; Carbidopa; Carboxy-Lyases; Compulsive Behavior; Drug Therapy, Combination; Drug Tolerance; Extinction, Psychological; Feeding Behavior; Humans; Immobilization; Lesch-Nyhan Syndrome; Nutritional Physiological Phenomena; Protective Devices; Self Mutilation

1976
L-5-hydroxytryptophan in treatment of several different syndromes in which myoclonus is prominent.
    Neurology, 1976, Volume: 26, Issue:12

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Child, Preschool; Drug Evaluation; Female; Humans; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Movement; Muscle Contraction; Myoclonus; Syndrome

1976
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
    Transactions of the American Neurological Association, 1976, Volume: 101

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Myoclonus; Serotonin

1976
Exposure to high pressure may produce the 5-HT behavioral syndrome in rats.
    Undersea biomedical research, 1990, Volume: 17, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Atmospheric Pressure; Behavior, Animal; Brain; Carbidopa; Central Nervous System Diseases; Fenclonine; High Pressure Neurological Syndrome; Hydroxyindoleacetic Acid; Male; Niacinamide; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1990
Development of pseudobullous morphea and scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:2 Pt 1

    Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Chronic Disease; Depression; Drug Therapy, Combination; Eosinophilia-Myalgia Syndrome; Humans; Male; Parkinson Disease; Scleroderma, Localized

1991
Palatal myoclonus: treatment with 5-hydroxytryptophan and carbidopa.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Therapy, Combination; Humans; Male; Myoclonus; Palatal Muscles

1990
Improvement of action myoclonus by an administration of 5-hydroxytryptophan and carbidopa in a child with muscular subsarcolemmal hyperactivity.
    Brain & development, 1990, Volume: 12, Issue:5

    Topics: 5-Hydroxytryptophan; Carbidopa; Child, Preschool; Humans; Male; Muscles; Muscular Diseases; Myoclonus

1990
Further evidence for an anomalous regulation of cortical 5-HT2 receptors: studies with 5-HT precursors.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Carbidopa; Cerebral Cortex; Drug Interactions; Ketanserin; Male; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tryptophan

1990
Development of tolerance to the wet-dog shake behaviour but not the increase in seizure threshold induced by L-5-hydroxytryptophan during continued treatment in rats.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Body Weight; Brain Chemistry; Carbidopa; Drug Interactions; Drug Tolerance; Female; Hydroxyindoleacetic Acid; Movement Disorders; Rats; Rats, Inbred Strains; Seizures; Serotonin

1985
Prolactin release after 5-hydroxytryptophan treatment requires an intact neurointermediate pituitary lobe.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dopamine; Hydroxyindoleacetic Acid; Male; Median Eminence; Norepinephrine; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Prolactin; Rats; Rats, Inbred Strains; Serotonin

1986
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
    Neuropsychobiology, 1985, Volume: 14, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Middle Aged; Self Mutilation; Suicide, Attempted

1985
Biochemistry and therapeutics of posthypoxic myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electroencephalography; gamma-Aminobutyric Acid; Glycine; Humans; Hydroxyindoleacetic Acid; Hypoxia; Methysergide; Models, Biological; Myoclonus; Prednisone; Serotonin; Tryptophan; Valproic Acid

1986
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; Methysergide; Myoclonus

1986
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pigs; Hydroxyindoleacetic Acid; Indoles; Monoamine Oxidase Inhibitors; Myoclonus; Pargyline; Piperazine; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tryptamines; Tryptophan

1986
Neurotransmitter therapy and diet in malignant phenylketonuria.
    European journal of pediatrics, 1987, Volume: 146, Issue:1

    Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias

1987
Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Cats; Coronary Disease; Female; Heart; Heart Rate; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenelzine; Serotonin; Ventricular Fibrillation

1987
Central versus peripheral effects on temperature preference and body temperature following alteration of 5-HT in maturing mice.
    Physiology & behavior, 1989, Volume: 46, Issue:2

    Topics: 5-Hydroxytryptophan; Aging; Amidines; Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Carbidopa; Carboxy-Lyases; Central Nervous System; Double-Blind Method; Drug Interactions; Hydrazines; Injections, Intraperitoneal; Mice; Peripheral Nerves; Piperidines; Serotonin Antagonists

1989
Monoamine oxidase inhibitory properties of milacemide in rats.
    Life sciences, 1989, Volume: 44, Issue:15

    Topics: 5-Hydroxytryptophan; Acetamides; Animals; Carbidopa; Cerebral Cortex; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Reference Values; Stereotyped Behavior; Tranylcypromine

1989
Serotonin and 5-hydroxytryptophan on blood pressure and renal blood flow in anesthetized rats.
    The American journal of the medical sciences, 1989, Volume: 297, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Dose-Response Relationship, Drug; Indomethacin; Male; Rats; Rats, Inbred Strains; Renal Circulation; Serotonin; Vascular Resistance

1989
5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats.
    Journal of hypertension, 1989, Volume: 7, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Carbidopa; Hypertension; Male; Rats; Rats, Inbred SHR; Serotonin; Weight Loss

1989
The modulation of head-twitch behaviour by drugs acting on beta-adrenoceptors: evidence for the involvement of both beta 1- and beta 2-adrenoceptors.
    Psychopharmacology, 1986, Volume: 88, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Receptors, Adrenergic, beta; Stereotyped Behavior; Time Factors

1986
Folinic acid therapy in treatment of dihydropteridine reductase deficiency.
    The Journal of pediatrics, 1987, Volume: 110, Issue:1

    Topics: 5-Hydroxytryptophan; Brain; Carbidopa; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Infant, Newborn; Leucovorin; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias

1987
Effects of antidepressant drug combinations on cortical 5-HT2 receptors and wet-dog shakes in rats.
    European journal of pharmacology, 1985, Dec-03, Volume: 118, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Carbidopa; Cerebral Cortex; Citalopram; Drug Interactions; Fenfluramine; Male; Methoxydimethyltryptamines; Paroxetine; Phenelzine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Time Factors

1985
Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; beta-Endorphin; Carbidopa; Drug Therapy, Combination; Endorphins; Humans; Migraine Disorders; Pain; Sensory Thresholds

1986
The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism.
    Psychopharmacology, 1986, Volume: 90, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Carbidopa; Drug Synergism; Fenclonine; Indoles; Lithium; Male; Methoxydimethyltryptamines; Motor Activity; Naphthalenes; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes

1986
p,p'-DDT-induced myoclonus in mice: the effect of enhanced 5-HT neurotransmission.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; DDT; Female; Mice; Mice, Inbred Strains; Myoclonus; Paroxetine; Piperidines; Serotonin; Synaptic Transmission; Tryptophan

1985
Successful long term therapy of biopterin deficiency.
    Journal of inherited metabolic disease, 1987, Volume: 10, Issue:3

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Dihydropteridine Reductase; Female; Humans; Infant, Newborn; Levodopa; Liver; Neopterin; Phenylalanine; Phenylalanine Hydroxylase

1987
Drug-induced myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Anesthetics; Animals; Anti-Bacterial Agents; Antidepressive Agents; Bismuth; Carbidopa; Electroencephalography; Gasoline; Guinea Pigs; Humans; Hydrocarbons, Brominated; Imipramine; Levodopa; Methysergide; Models, Biological; Myoclonus; Parkinson Disease; Sleep

1986
[Sclerodermiform and poikilodermic syndrome during treatment with carbidopa and 5-hydroxytryptophan. Culture of fibroblasts with biochemical analysis of collagen metabolism].
    Annales de dermatologie et de venereologie, 1986, Volume: 113, Issue:1

    Topics: 5-Hydroxytryptophan; Carbidopa; Cells, Cultured; Collagen; Drug Therapy, Combination; Fibroblasts; Humans; Scleroderma, Systemic

1986
Prenatal stress increases the behavioral response to serotonin agonists and alters open field behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Behavior, Animal; Carbidopa; Crowding; Female; Methoxydimethyltryptamines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior; Stress, Psychological

1986
Suppression and potentiation of 5-hydroxytryptophan-induced hypoglycaemia by alpha-monofluoromethyldopa: correlation with the accumulation of 5-hydroxytryptamine in the liver.
    British journal of pharmacology, 1987, Volume: 90, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Brain; Carbidopa; Carboxy-Lyases; Kidney; Lipopolysaccharides; Liver; Male; Methyldopa; Mice; Serotonin

1987
Imipramine administered during an infantile period modifies sex difference in L-5-hydroxytryptophan-induced head shakes in rats.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:4

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Behavior, Animal; Carbidopa; Desipramine; Drug Interactions; Female; Imipramine; Male; Rats; Rats, Inbred Strains; Sex Factors

1987
The maturational onset of the 5-HT mediated head twitch in mice.
    Physiology & behavior, 1987, Volume: 41, Issue:1

    Topics: 5-Hydroxytryptophan; Aging; Animals; Carbidopa; Female; Humans; Male; Mice; Motor Activity; Pargyline; Serotonin; Tryptophan

1987
Objective quantification of tremor in conscious unrestrained rats, exemplified with 5-hydroxytryptamine-mediated tremor.
    Journal of pharmacological methods, 1985, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dose-Response Relationship, Drug; Male; Pargyline; Rats; Rats, Inbred Strains; Time Factors; Tremor

1985
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:6

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine

1985
Evidence that the accumulation of 5-hydroxytryptamine in the liver but not in the brain may cause the hypoglycaemia induced by 5-hydroxytryptophan.
    British journal of pharmacology, 1985, Volume: 85, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Dose-Response Relationship, Drug; Hypoglycemia; Liver; Male; Mice; Pargyline; Serotonin; Time Factors

1985
Formation of serotonin by rat kidneys in vivo.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Carbidopa; Diuresis; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Rats; Rats, Inbred Strains; Renal Circulation; Serotonin

1985
Letter: Treatment of post-anoxic intention myoclonus.
    Lancet (London, England), 1974, Jun-22, Volume: 1, Issue:7869

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus

1974
L-dopa hypotension in dogs: evidence for mediation through 5-HT release.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Carbidopa; Chlorpromazine; Depression, Chemical; Dogs; Drug Interactions; Female; Fenclonine; Haloperidol; Heart Rate; Levodopa; Male; Methysergide; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Serotonin; Time Factors; Yohimbine

1974
(S)-norepinephrine in the tissues of mice and rats given racemic erythro-3,4-dihydroxyphenylserine (DOPS).
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Aug-15, Volume: 11, Issue:16

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Brain Chemistry; Carbidopa; Catechols; Decarboxylation; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Myocardium; Norepinephrine; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Tyramine

1972
Effects of chlorimipramine and protriptyline on the hyperactivity induced by 5-hydroxytryptophan after peripheral decarboxylase inhibition in mice.
    Journal of neural transmission, 1973, Volume: 34, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Brain; Carbidopa; Carboxy-Lyases; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; Norepinephrine; Sensory Receptor Cells; Serotonin

1973
Monoamine precursors and copulatory behavior in the male rat.
    Acta physiologica Scandinavica. Supplementum, 1973, Volume: 400

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbidopa; Carboxy-Lyases; Castration; Copulation; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ejaculation; Female; Hydrazines; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nialamide; Pargyline; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone; Time Factors

1973
Studies on DL-5-hydroxytryptophan-induced hyperactivity in mice.
    Advances in biochemical psychopharmacology, 1974, Volume: 10

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Antidepressive Agents; Blood-Brain Barrier; Brain; Carbidopa; Carboxy-Lyases; Catecholamines; Dibenzazepines; Drug Synergism; Methyltyrosines; Mice; Motor Activity; Neurons; Receptors, Cholinergic; Serotonin; Stimulation, Chemical

1974
L-5-hydroxytryptophan. Correlation between anticonvulsant effect and increases in levels of 5-hydroxyindoles in plasma and brain.
    Neuropharmacology, 1984, Volume: 23, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain Chemistry; Carbidopa; Electroshock; Female; Hydroxyindoleacetic Acid; Rats; Rats, Inbred Strains; Serotonin; Time Factors

1984
Differential effect of carbidopa on the concentration of rat pineal and hypothalamic indoleamines.
    Journal of pineal research, 1984, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Hydroxyindoleacetic Acid; Hypothalamus; Male; Melatonin; Organ Specificity; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin

1984
An electron microscopic radioautographic identification of the APUD endocrine cells in the rat gastric pyloric glands.
    Gastroenterology, 1981, Volume: 81, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; APUD Cells; Autoradiography; Carbidopa; Gastric Mucosa; Male; Microscopy, Electron; Pylorus; Rats

1981
Effects of 5-HT receptor agonists and antagonists on a reflex response to radiant heat in normal and spinally transected rats.
    Pain, 1982, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Circadian Rhythm; Hot Temperature; Male; Metergoline; Methiothepin; Mianserin; Neurotransmitter Agents; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord

1982
Identification of the APUD endocrine cells of rat fundic mucosa by means of combined amine fluorescence and electron microscopy.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1984, Volume: 32, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Animals; APUD Cells; Carbidopa; Fluorescence; Gastric Mucosa; Male; Microscopy, Electron; Rats; Rats, Inbred Strains

1984
Biopterin synthesis defect. Treatment with L-dopa and 5-hydroxytryptophan compared with therapy with a tetrahydropterin.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acid Metabolism, Inborn Errors; Biopterins; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Female; Humans; Infant; Levodopa; Neopterin; Neurotransmitter Agents; Pteridines; Pterins

1984
Plasma accumulation of metabolism of orally administered single dose L-5-hydroxytryptophan in man.
    Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:3

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Humans; Hydroxyindoleacetic Acid; Intestinal Absorption; Serotonin

1981
Study of serotonin in neuropsychiatric disorders.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:8

    Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Middle Aged; Myoclonus; Nervous System Diseases; Psychotic Disorders; Serotonin

1982
Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; Carbidopa; Drug Interactions; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Protein Binding

1982
Kinetics of l-5-hydroxytryptophan in healthy subjects.
    Psychiatry research, 1982, Volume: 7, Issue:3

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Carbidopa; Half-Life; Humans; Hydroxyindoleacetic Acid; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Serotonin

1982
Fluoxetine in the treatment of intention myoclonus.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Blood Platelets; Carbidopa; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Myoclonus; Propylamines; Serotonin; Time Factors

1983
Alterations in brain 5HT and tryptamine content during indoleamine-induced myoclonus in guinea pigs.
    Biochemical pharmacology, 1983, Jun-15, Volume: 32, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Drug Interactions; Female; Guinea Pigs; Hydroxyindoleacetic Acid; Myoclonus; Pargyline; Serotonin; Tryptamines; Tryptophan

1983
Toxic oil syndrome (Spanish oil disease) and chemically induced scleroderma-like conditions.
    The Journal of rheumatology, 1984, Volume: 11, Issue:3

    Topics: 5-Hydroxytryptophan; Bleomycin; Brassica; Carbidopa; Humans; Oils; Pentazocine; Plastics; Scleroderma, Systemic; Solvents; Vinyl Chloride; Vinyl Compounds

1984
Effect of some serotoninergic agents on the rectal temperature of the domestic fowl (Gallus domesticus).
    Neuropharmacology, 1984, Volume: 23, Issue:12A

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Body Temperature; Body Temperature Regulation; Carbidopa; Cattle; Chickens; Citalopram; Cyproheptadine; Fenclonine; Lysergic Acid Diethylamide; Male; Methysergide; Propylamines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors

1984
Evidence that the effects of 5-hydroxytryptophan on the secretion of ACTH and growth hormone in dogs are not mediated by central release of serotonin.
    Neuroendocrinology, 1982, Volume: 34, Issue:1

    Topics: 11-Hydroxycorticosteroids; 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Benserazide; Carbidopa; Dogs; Female; Growth Hormone; Kinetics; Male; Metergoline; Serotonin

1982
Inhibition of respiratory neural discharges by clonidine and 5-hydroxytryptophan.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Cats; Chemoreceptor Cells; Clonidine; Female; Male; Phenoxybenzamine; Phrenic Nerve; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Respiratory Center; Synaptic Transmission; Tolazoline

1982
Effects of carbidopa on the cerebral accumulation of exogenous L-5-hydroxytryptophan in mice.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Biological Availability; Brain Chemistry; Carbidopa; Female; Mice; Mice, Inbred Strains

1984
The effects of intraventricular prolactin infusions on pituitary responsiveness to thyrotropin-releasing hormone, 5-hydroxytryptophan or morphine in rhesus monkeys.
    Brain research, 1983, Jan-10, Volume: 258, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Castration; Estradiol; Female; Hydrocortisone; Kinetics; Macaca mulatta; Male; Morphine; Pituitary Gland; Prolactin; Sheep; Thyrotropin-Releasing Hormone

1983
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
    Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:3

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines

1983
Brain 5-hydroxytryptamine level, metabolism, and binding in E1 mice.
    Neurochemical research, 1983, Volume: 8, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dihydroxyphenylalanine; Mice; Mice, Inbred Strains; Monoamine Oxidase; Physical Stimulation; Serotonin

1983
Effects of manipulating serotonin on the incidence of ovulation in the rat.
    The Journal of endocrinology, 1980, Volume: 87, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Estradiol; Estrogens; Estrus; Female; Fenclonine; Injections, Intraperitoneal; Injections, Subcutaneous; Luteinizing Hormone; Ovulation; Pregnancy; Progesterone; Rats; Serotonin

1980
Serotonin receptor activation in rats previously deprived of REM sleep.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Carbidopa; Male; Methoxydimethyltryptamines; Pargyline; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sleep Deprivation; Sleep, REM; Tryptophan

1983
Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone.
    Neuropharmacology, 1983, Volume: 22, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Haloperidol; Male; Methamphetamine; Motor Activity; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine; Tryptophan

1983
Reserpine-induced rigidity in rats: drug effects on muscle tone from corpus striatum and nucleus accumbens.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Carbidopa; Corpus Striatum; Male; Muscle Rigidity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reserpine; Septal Nuclei; Trifluoperazine

1983
Serotonin formation in nonblood-perfused rat kidneys.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Chromatography, High Pressure Liquid; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renal Veins; Serotonin; Vascular Resistance

1984
Locomotion in the rat after 5-hydroxy-L-tryptophan.
    European journal of pharmacology, 1984, Feb-17, Volume: 98, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Female; Locomotion; Rats

1984
Regulation of prolactin and growth hormone secretion. Site and mechanism of action of thyrotropin-releasing hormone, L-dopa and L-5-hydroxytryptophan in unanesthetized dogs.
    Neuroendocrinology, 1980, Volume: 30, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Depression, Chemical; Dogs; Female; Growth Hormone; Hormones; Levodopa; Male; Metergoline; Prolactin; Radioimmunoassay; Serotonin; Sex Factors; Stimulation, Chemical; Thyrotropin-Releasing Hormone

1980
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan

1982
From the NIH: New treatment for myoclonus patients.
    JAMA, 1980, May-02, Volume: 243, Issue:17

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Depression, Chemical; Humans; Myoclonus; Serotonin

1980
Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:4

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Myoclonus

1980
l-5-Hydroxytryptophan in depression: the first substitution therapy in psychiatry? The treatment of 99 out-patients with 'therapy-resistant' depressions.
    Neuropsychobiology, 1980, Volume: 6, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aged; Antidepressive Agents; Carbidopa; Depression; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Sex Factors

1980
Evidence for a peripheral effect of sertonin or metabolites in 5-hydroxytryptophan-induced hypothermia.
    Neuropharmacology, 1980, Volume: 19, Issue:8

    Topics: 5-Hydroxytryptophan; Amidines; Animals; Benserazide; Body Temperature; Carbidopa; Dose-Response Relationship, Drug; Male; Phenyl Ethers; Rats; Serotonin; Temperature; Time Factors

1980
Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations.
    Annals of neurology, 1980, Volume: 7, Issue:6

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clonazepam; Diarrhea; Drug Therapy, Combination; Electroencephalography; Electromyography; Humans; Middle Aged; Myoclonus; Nausea; Phenobarbital; Serotonin

1980
Drug-related scleroderma-like illness. The Fine page.
    International journal of dermatology, 1981, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Carbidopa; Drug Combinations; Humans; Kynurenine; Scleroderma, Systemic

1981
Peripheral conversion of L-5-hydroxytryptophan to serotonin induces drinking in rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drinking Behavior; Female; Methysergide; Rats; Receptors, Serotonin; Serotonin

1981
Serotonin regulation of corticoid secretion in infant rats.
    Developmental psychobiology, 1981, Volume: 14, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenal Cortex; Animals; Animals, Newborn; Carbidopa; Corticosterone; Dose-Response Relationship, Drug; Fluoxetine; Rats; Serotonin; Weaning

1981
Long-term infusion of L-5-hydroxytryptophan increases brain serotonin turnover and decreases blood pressure in normotensive rats.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain; Carbidopa; Catecholamines; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1982
Serotonergic approaches to the modification of behavior in the Lesch-Nyhan Syndrome.
    Applied research in mental retardation, 1980, Volume: 1, Issue:1-2

    Topics: 5-Hydroxytryptophan; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Lesch-Nyhan Syndrome; Male; Videotape Recording

1980
Segmental action and stimuli-sensitive myoclonus with acute onset. A case report.
    Italian journal of neurological sciences, 1980, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Acute Disease; Adult; Angiography; Carbidopa; Carotid Arteries; Cerebrovascular Circulation; Clonazepam; Diazepam; Electric Stimulation; Electroencephalography; Humans; Male; Myoclonus; Vertebral Artery

1980
Survival of neonatal rats during hypoxia after monoamine stimulating agents.
    Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Apomorphine; Biogenic Amines; Carbidopa; Female; Hypoxia; Levodopa; Pregnancy; Rats; Rats, Inbred Strains; Time Factors

1982
[Oral bioavailability of an L-5-HTP/carbidopa tablet].
    Archivos de farmacologia y toxicologia, 1982, Volume: 8, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Biological Availability; Carbidopa; Dogs; Drug Combinations; Male; Tablets

1982
Pharmacological evidence that stimulation of central serotonergic pathways increases renin secretion.
    Neuroendocrinology, 1980, Volume: 30, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carbidopa; Denervation; Dogs; Female; Kidney; Male; Metergoline; Renin; Serotonin; Tryptophan

1980
Dopamine and serotonin turnover rate in the retina of rabbit, rat, goldfish, and Eugerres plumieri: light effects in goldfish and rat.
    Journal of neuroscience research, 1994, Dec-01, Volume: 39, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Carbidopa; Dopamine; Fenclonine; Goldfish; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Light; Male; Methyltyrosines; Pargyline; Perciformes; Rabbits; Rats; Rats, Sprague-Dawley; Retina; Serotonin; Species Specificity

1994
Low responsiveness to agents evoking 5-HT2 receptor-mediated behaviors in Sardinian alcohol-preferring rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:1

    Topics: 5-Hydroxytryptophan; Alcohol Drinking; Amphetamines; Animals; Behavior, Animal; Carbidopa; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Peptide Fragments; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Agents; Serotonin Receptor Agonists; Substance P

1995
Abnormal serotonergic stimulation of cortisol production in obstructive sleep apnea.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Body Mass Index; Brain; Carbidopa; Case-Control Studies; Humans; Hydrocortisone; Male; Receptors, Serotonin; Serotonin; Sleep Apnea Syndromes; Time Factors; Wakefulness

1995
Effects of glucocorticoids on 5-HT1A presynaptic function in the mouse.
    Psychopharmacology, 1994, Volume: 114, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Carbidopa; Corticosterone; Dose-Response Relationship, Drug; Glucocorticoids; Male; Mice; Receptors, Presynaptic; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior

1994
Tetrahydrobiopterin deficiency and an international database of patients.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Information Systems; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pterins; Registries

1993
Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carrier Proteins; Corpus Striatum; Dopamine; Drug Synergism; Fluoxetine; Frontal Lobe; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tetrodotoxin

1996
Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
    Nature structural biology, 2001, Volume: 8, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Binding Sites; Carbidopa; Crystallography, X-Ray; Dopa Decarboxylase; Drug Design; Humans; Kidney; Levodopa; Ligands; Models, Molecular; Parkinson Disease; Pliability; Protein Structure, Secondary; Swine

2001
Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis.
    European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3

    Topics: 5-Hydroxytryptophan; Animals; Antiemetics; Behavior, Animal; Carbidopa; Central Nervous System; Dopamine Agents; Dose-Response Relationship, Drug; Dronabinol; Emetics; Female; Male; Peripheral Nervous System; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews

2004
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
    Annals of neurology, 2005, Volume: 58, Issue:1

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures

2005
Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy.
    Pediatric neurology, 2006, Volume: 35, Issue:5

    Topics: 5-Hydroxytryptophan; Adolescent; Alcohol Oxidoreductases; Antidepressive Agents, Second-Generation; Carbidopa; Child; Dopamine Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Levodopa; Male; Metabolism, Inborn Errors; Treatment Outcome

2006
Serum prolactin as a tool for the follow-up of treated DHPR-deficient patients.
    Journal of inherited metabolic disease, 2008, Volume: 31 Suppl 2

    Topics: 5-Hydroxytryptophan; Aromatic Amino Acid Decarboxylase Inhibitors; Biomarkers; Carbidopa; Child, Preschool; Dietary Proteins; Dihydropteridine Reductase; Dopa Decarboxylase; Dopamine Agents; Drug Monitoring; Drug Therapy, Combination; Enzyme Inhibitors; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Italy; Levodopa; Monoamine Oxidase Inhibitors; Mutation; Neonatal Screening; Neurologic Examination; Phenotype; Phenylketonurias; Prolactin; Selegiline; Time Factors; Treatment Outcome

2008
How physician obesity specialists use drugs to treat obesity.
    Obesity (Silver Spring, Md.), 2009, Volume: 17, Issue:9

    Topics: 5-Hydroxytryptophan; Anti-Obesity Agents; Carbidopa; Drug Combinations; Drug Labeling; Drug Therapy, Combination; Drug Utilization; Guideline Adherence; Health Care Surveys; Humans; Medicine; Obesity; Phentermine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prescription Drugs; Retrospective Studies; Specialization; Surveys and Questionnaires; Time Factors; Treatment Outcome; United States; Weight Loss

2009
5-HT precursor loading, but not 5-HT receptor agonists, increases motor function after spinal cord contusion in adult rats.
    Experimental neurology, 2010, Volume: 221, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Cervical Vertebrae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Enzyme Inhibitors; Exercise Test; Exploratory Behavior; Female; Fenfluramine; Hindlimb; Laminectomy; Motor Activity; Movement Disorders; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Spinal Cord Injuries; Stereotyped Behavior; Time Factors; Tremor; Up-Regulation

2010
[(11)C]5-HTP and microPET are not suitable for pharmacodynamic studies in the rodent brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Carbon Radioisotopes; Enzyme Inhibitors; Hydrazines; Male; Models, Biological; Positron-Emission Tomography; Rats; Rats, Wistar; Sensitivity and Specificity; Serotonin; Tissue Distribution; Tryptophan

2014
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine

2014
Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.
    Journal of neurochemistry, 2015, Volume: 135, Issue:4

    Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Gene Expression Regulation; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Motor Activity; Norepinephrine; Serotonin; Time Factors; Tryptophan Hydroxylase

2015
Spinal Cord Hemisection Facilitates Aromatic L-Amino Acid Decarboxylase Cells to Produce Serotonin in the Subchronic but Not the Chronic Phase.
    Neural plasticity, 2015, Volume: 2015

    Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Chronic Disease; Hindlimb; Male; Nerve Fibers; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord Injuries; Tail; Thoracic Vertebrae

2015
What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa.
    Pediatric neurology, 2016, Volume: 59

    Topics: 5-Hydroxytryptophan; Adolescent; Anti-Dyskinesia Agents; Carbidopa; Diseases in Twins; Dopamine Agonists; Drug Combinations; Dystonia; Female; Humans; Levodopa; Male; Metabolism, Inborn Errors; Psychomotor Disorders; Serotonin Agents

2016
Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.
    Journal of the neurological sciences, 2017, Jul-15, Volume: 378

    Topics: 5-Hydroxytryptophan; Adult; Atrophy; Carbidopa; Central Nervous System Agents; Fatal Outcome; Female; Humans; Paraparesis; Pregnancy; Pregnancy Complications; Spinal Cord Diseases; Young Adult

2017
Improvement of Self-Injury With Dopamine and Serotonin Replacement Therapy in a Patient With a Hemizygous PAK3 Mutation: A New Therapeutic Strategy for Neuropsychiatric Features of an Intellectual Disability Syndrome.
    Journal of child neurology, 2018, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Brain; Carbidopa; Dopamine; Drug Combinations; Humans; Intellectual Disability; Levodopa; Male; Mutation; p21-Activated Kinases; Psychotropic Drugs; Self-Injurious Behavior; Serotonin; Syndrome

2018
Anorectic interaction and safety of 5-hydroxytryptophan/carbidopa plus phentermine or diethylpropion in rat.
    Behavioural pharmacology, 2021, 08-01, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Appetite Depressants; Biomarkers, Pharmacological; Carbidopa; Cardiovascular System; Diethylpropion; Drug Combinations; Drug Dosage Calculations; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Obesity; Phentermine; Rats

2021
Acute treatment with 5-hydroxytryptophan increases social approach behaviour but does not activate serotonergic neurons in the dorsal raphe nucleus in juvenile male BALB/c mice: A model of human disorders with deficits of sociability.
    Journal of psychopharmacology (Oxford, England), 2022, Volume: 36, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Choice Behavior; Dorsal Raphe Nucleus; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Serotonergic Neurons; Serotonin; Social Behavior; Tryptophan Hydroxylase

2022
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007