5-hydroxytryptophan has been researched along with carbidopa in 166 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 126 (75.90) | 18.7374 |
1990's | 15 (9.04) | 18.2507 |
2000's | 12 (7.23) | 29.6817 |
2010's | 11 (6.63) | 24.3611 |
2020's | 2 (1.20) | 2.80 |
Authors | Studies |
---|---|
Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ | 1 |
Quik, M; Sourkes, TL | 1 |
Butler, IJ; Koslow, SH | 1 |
Rubin, W; Schwartz, B | 3 |
Chadwick, D; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
Bartholomé, K; Byrd, DJ | 1 |
Anderson, DR; Guy, J; Quigley, HA | 1 |
Lown, B; Rabinowitz, SH | 1 |
Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA | 1 |
Boggan, WO; Buckholtz, NS; Meyer, JS | 1 |
Levin, SL | 1 |
de Fine Olivarius, B; Dupont, E; Magnussen, I; Prange-Hansen, A | 1 |
Borden, M; Kaufman, I; Kulovich, S; Nyhan, WL; Sweetman, L | 1 |
Deshmukh, VD; Haufrect, DB; Jacob, RH; Mathew, NT; Meyer, JS; Morrell, RM; Perez, FI; Welch, KM | 1 |
Gale, CC; Garcia, JF; Mixter, RC; Ruch, W; Russell, RM | 1 |
Fahn, S | 1 |
de Fine Olivarius, B; Dupont, E; Engbaek, F; Magnussen, I | 1 |
Becker, L; Hurwic, MJ; Kupietz, SS; Sverd, J; Winsberg, BG | 1 |
Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD | 1 |
Engbaek, F; Magnussen, I | 1 |
Appel, JB; Carter, RB; Dykstra, LA; Leander, JD | 1 |
Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG | 1 |
Connors, MH; Dorsa, DM | 1 |
Fozard, JR; Palfreyman, MG | 1 |
Rosenbaum, D; Van Woert, MH | 1 |
Blundell, JE; Latham, CJ | 1 |
Hjälmås, K; Rubenson, A; Sillén, U | 1 |
Barchas, JD; Berger, PA; Brodie, KH; Sack, R; Zarcone, VP | 1 |
Bigelow, LB; Gillin, JC; Walls, P; Wyatt, RJ | 1 |
Bowers, MB; Howieson, J; Rosenbaum, D; Van Woert, MH | 1 |
Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
Gillin, JC; Magyar, RL; Wyatt, RJ | 1 |
Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH | 1 |
Sethy, VH; Van Woert, MH | 2 |
Stancer, HC; Warsh, JJ | 2 |
De Léan, J; Hornykiewicz, O; Richardson, JC | 1 |
Nyhan, WL | 1 |
Growdon, JH; Shahani, BT; Young, RR | 1 |
Anderson, LT; Dancis, J; Herrmann, L | 1 |
Engel, J; Katzman, R; Sharpless, N; Thal, L; Wolfson, L | 1 |
Eckardt, MJ; George, DT; Lindquist, T; Linnoila, M; Martin, PR; Mathis, C; Moss, H; Rawlings, RR | 1 |
Brammer, NT; Charlett, A; Doré, CJ; Fletcher, A; Hudson, S; Minchin, MC; Wann, KT; Wardley-Smith, B | 1 |
Joly, P; Lampert, A; Lauret, P; Thomine, E | 1 |
Bhatt, M; Calne, D; Snow, B; Varelas, M | 1 |
Fukuyama, Y; Hayakawa, T; Nakano, K; Ohsawa, M; Shishikura, K; Suzuki, H | 1 |
Koshikawa, F; Koshikawa, N; Stephenson, JD | 2 |
Löscher, W; Pagliusi, SR | 1 |
Alper, RH; Fagin, KD; Johnston, CA; Negro-Vilar, A | 1 |
López-Ibor, JJ; Pérez de los Cobos, JC; Saiz-Ruiz, J | 1 |
Chung, EY; Rosenbaum, D; Van Woert, MH | 1 |
De Léan, J; Rewcastle, NB; Richardson, JC | 1 |
Jenner, P; Luscombe, G; Marsden, CD | 2 |
Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A | 1 |
Lehnert, H; Lombardi, F; Lorenzo, AV; Lown, B; Raeder, EA; Verrier, RL; Wurtman, RJ | 1 |
Clementi, RA; Ferguson, RK; Rotmensch, HH; Swanson, BN; Vlasses, PH | 1 |
Goodrich, C; Lechner, R; Slone, W | 1 |
Diamond, B; Fahn, S; Mena, MA; Pezzoli, G; Truong, DD | 1 |
Ding, XR; Itskovitz, HD; Stier, CT | 1 |
Brewer, TF; Itskovitz, HD; Sheridan, AM; Stier, CT; Werber, JL | 1 |
Handley, SL; Singh, L | 1 |
Butler, IJ; Irons, M; Kaufman, S; Langlais, PJ; Levy, HL; Milstien, S; O'Flynn, ME; Stack, CV | 1 |
Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G | 1 |
De Souza, RJ; Goodwin, GM; Green, AR; Wood, AJ | 1 |
Magnussen, I | 2 |
Pulmones, MT; Sansaricq, C; Snyderman, SE | 1 |
Byerley, WF; Grosser, BI; Judd, LL; Reimherr, FW | 1 |
Carvey, PM; Goetz, CG; Klawans, HL; Tanner, CM | 1 |
Chamson, A; Frey, J; Périer, C | 1 |
Peters, DA | 1 |
Endo, Y | 2 |
Fujii, T; Taguchi, H | 1 |
Eble, JP; Goodrich, C | 1 |
Carlsson, L; Elg, R; Hallberg, H | 1 |
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A | 1 |
Itskovitz, HD; Stier, CT | 1 |
Dijken, WA; Kamp, JS; Nolen, WA; van de Putte, JJ | 1 |
Chase, TN | 1 |
Antonaccio, MJ; Robson, RD | 1 |
Porter, CC; Stone, CA; Torchiana, ML | 1 |
Modigh, K | 2 |
Malmnäs, CO | 1 |
Löscher, W; Müller, F; Pagliusi, SR | 1 |
Frohman, CE; Hryhorczuk, LM; McIntyre, IM; Novak, EA; Oxenkrug, GF | 1 |
Berge, OG | 1 |
Hanley, WB; Kapatos, G; Kaufman, S; MacGregor, D; McInnes, RR; Milstien, S; Soldin, S; Van Loon, GR; Walsh, P; Warsh, JJ | 1 |
Jensen, TS; Magnussen, I; Rand, JH; Van Woert, MH | 1 |
Hwang, EC; Lowe, YH; Magnussen, I; Van Woert, MH | 1 |
Magnussen, I; Van Woert, MH | 1 |
Gerritsen, TW; Meijer, BA; van Praag, HM; Westenberg, HG | 1 |
Chung, E; Magnussen, I; Rosenbaum, D; Van Woert, MH | 1 |
Bell, MJ; Fam, AG; Rush, PJ | 1 |
Bodhankar, S; Osuide, G; Wambebe, C | 1 |
Ganong, WF; Kaplan, SL; Zimmermann, H | 1 |
Lalley, PM; McCrimmon, DR | 1 |
Van Woert, MH | 1 |
Herbert, J; Martensz, ND | 1 |
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS | 1 |
Hiramatsu, M | 1 |
Coen, CW; Franklin, M; Laynes, RW; MacKinnon, PC | 1 |
Carlini, EA; Santos, R | 1 |
Grahame-Smith, DG; Green, AR; Hammond, M; O'Shaughnessy, K; Schächter, M | 1 |
Johnels, B | 1 |
Itskovitz, HD; McKendall, G; Stier, CT | 1 |
Clarke, KA; Parker, AJ; Stirk, GC | 1 |
Curtius, HC; Endres, W; Niederwieser, A; Ohrt, B; Schaub, J; Wang, M | 1 |
Aubert, ML; Ganong, WF; Grumbach, MM; Holland, FJ; Kaplan, SL; Richards, GE | 1 |
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN | 1 |
Dunner, FJ; McCalley-Whitters, M; Nasrallah, HA; Smith, RE | 1 |
Magnussen, I; Nielsen-Kudsk, F | 1 |
van Hiele, LJ | 1 |
Carter, RB; Leander, JD | 1 |
Katzman, R; Sharpless, NS; Thal, LJ; Wolfson, L | 1 |
Fine, RM | 1 |
Barney, CC; Fregly, MJ; Greenleaf, JE; Kikta, DC; Threatte, RM | 1 |
Grota, LJ | 1 |
Echizen, H; Freed, CR | 1 |
Johnson, HG; Jones, KL; Kaufman, IA; Nyhan, WL | 1 |
Avanzini, G; Franceschetti, S; Lombardi, B; Passerini, A | 1 |
Hedner, T; Lundborg, P | 1 |
Obach, R; Pruñonosa, J; Vallés, J; Vallés, JM | 1 |
Ganong, WF; Zimmermann, H | 1 |
Baker, H; Gauthier, S; Magnussen, I; Osterland, CK; Sternberg, EM; Van Woert, MH; Young, SN | 1 |
Lima, L; Urbina, M | 1 |
Ciccocioppo, R; Gessa, GL; Massi, M; Panocka, I; Stefanini, E | 1 |
Ashwal, S; Bodensteiner, J; Franz, D; Haas, RH; Huang, Y; Pranzatelli, MR; Tate, E | 1 |
Gordon, EA; Hudgel, DW; Meltzer, HY | 1 |
Dick, H; Fink, G; Goodwin, GM; Young, AH | 1 |
Blau, N; Dhondt, JL | 1 |
Gudelsky, GA; Nash, JF | 1 |
Gordon, EA; Hudgel, DW | 1 |
Cabezas-Cerrato, J; Graña, M; Lado-Abeal, J; Rey, C | 1 |
Abeling, N; Bergmann, C; Blau, N; Häring, M; Häusler, M; Heimann, G; Ramaekers, VT; Senderek, J; Zerres, K | 1 |
Borri-Voltattorni, C; Burkhard, P; Dominici, P; Jansonius, JN; Malashkevich, VN | 1 |
Cohen, AF; de Kam, ML; de Rijk, R; Gijsman, HJ; Pieters, MS; Schoemaker, RC; van der Post, J; van Gerven, JM; Weemaes, M | 1 |
Darmani, NA; Johnson, JC | 1 |
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ | 1 |
Bergström, M; Eriksson, B; Långström, B; Lu, L; Oberg, K; Orlefors, H; Sundin, A | 1 |
Assmann, B; Blau, N; Echenne, B; Hoffmann, GF; Lutz, T; Penzien, JM; Roubertie, A; Thöny, B | 1 |
Garske, U; Orlefors, H; Sundin, A | 1 |
de Kam, ML; de Rijk, R; Gijsman, HJ; Hoeberechts-Lefrandt, DH; Jacobs, GE; Schoemaker, RC; Smarius, LJ; van der Post, JP; van Gerven, JM; van Pelt, J; Zitman, FG | 1 |
Concolino, D; Moricca, MT; Muzzi, G; Pascale, MG; Rapsomaniki, M; Strisciuglio, P | 1 |
de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG | 1 |
Greenway, FL; Hendricks, EJ; Rothman, RB | 1 |
Dugan, EA; Hayashi, Y; Jacob-Vadakot, S; McBride, S; Murray, M; Olexa, R; Shumsky, JS; Simansky, K | 1 |
Cohen, AF; de Kam, ML; der Grond, Jv; Jacobs, GE; Langeveld, TJ; Teeuwisse, WM; van Gerven, JM; van Pelt, J; Verhagen, JC; Zitman, FG | 1 |
Popper, CW | 1 |
de Vries, EF; Di Gialleonardo, V; Dierckx, RA; Kema, IP; Ramakrishnan, NK; van Waarde, A; Visser, AK; Willemsen, AT | 1 |
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D | 1 |
Anastasia, A; Carli, M; Invernizzi, RW; Kostoula, C; Mainolfi, P; Sacchetti, G; Villani, C | 1 |
Azam, A; Azam, B; Jensen, DB; Wienecke, J; Zhang, M | 1 |
Friedman, JR | 1 |
Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R | 1 |
Bartel, T; Blydt-Hansen, I; Connolly, MB; Horvath, GA; Race, S; Ross, CJ; Tarailo-Graovac, M; Van Allen, MI; van Karnebeek, CDM; Wasserman, WW | 1 |
Flores-Murrieta, FJ; Huerta-Cruz, JC; Lara-Padilla, E; Limón-Bernal, E; Reyes-García, JG; Roa-Coria, JE; Rocha-González, HI; Ruíz-Velasco, IRC; Zúñiga-Romero, Á | 1 |
Hale, MW; Kent, S; Lesku, JA; Lowry, CA; Payet, JM; Russo, AM | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
5 review(s) available for 5-hydroxytryptophan and carbidopa
Article | Year |
---|---|
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception | 1976 |
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans | 1987 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors | 1974 |
Nuclear imaging of neuroendocrine tumours.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Carbidopa; Glucose-6-Phosphate; Humans; Levodopa; Neuroendocrine Tumors; Positron-Emission Tomography; Receptors, Somatostatin; Somatostatin | 2007 |
Mood disorders in youth: exercise, light therapy, and pharmacologic complementary and integrative approaches.
Topics: 5-Hydroxytryptophan; Adolescent; Antidepressive Agents, Second-Generation; Carbidopa; Child; Complementary Therapies; Depressive Disorder, Major; Enzyme Inhibitors; Exercise Therapy; Humans; Hypericum; Integrative Medicine; Mood Disorders; Phototherapy; Phytotherapy; S-Adenosylmethionine; Treatment Outcome | 2013 |
22 trial(s) available for 5-hydroxytryptophan and carbidopa
Article | Year |
---|---|
Effects of L-5-hydroxytryptophan in autistic children.
Topics: 5-Hydroxytryptophan; Attention; Autistic Disorder; Brain; Carbidopa; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Serotonin; Social Adjustment; Verbal Behavior | 1978 |
The indoleamine hypothesis of depression: an overview and pilot study.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydroxycorticosteroids; Hydroxyindoleacetic Acid; Male; Middle Aged; Models, Neurological; Serotonin | 1977 |
Clinical effects of L-5-hydroxytryptophan administration in chronic schizophrenic patients.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia | 1979 |
Serotonin and myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoles; Male; Middle Aged; Myoclonus; Serotonin | 1976 |
The effect of L-5-hydroxytryptophan on self-mutilatin in Lesch-Nyhan disease: a negative report.
Topics: 5-Hydroxytryptophan; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Lesch-Nyhan Syndrome; Male; Self Mutilation | 1976 |
Pharmacologic maintenance of abstinence in patients with alcoholism: no efficacy of 5-hydroxytryptophan or levodopa.
Topics: 5-Hydroxytryptophan; Adult; Alcoholism; Analysis of Variance; Carbidopa; Double-Blind Method; Drug Therapy, Combination; Educational Status; Female; Humans; Intelligence Tests; Levodopa; Male; Memory; Middle Aged; Neuropsychological Tests; Time Factors | 1992 |
Effect of repeated doses of L-5-hydroxytryptophan and carbidopa on prolactin and aldosterone secretion in man.
Topics: 5-Hydroxytryptophan; Adult; Aldosterone; Carbidopa; Dexamethasone; Humans; Hydroxyindoleacetic Acid; Male; Natriuresis; Prolactin | 1989 |
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans | 1987 |
L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Drug Resistance; Drug Therapy, Combination; Fluvoxamine; Follow-Up Studies; Humans; Maprotiline; Middle Aged; Oximes; Random Allocation; Serotonin Antagonists; Stereoisomerism; Tranylcypromine | 1985 |
Myoclonus and L-5-hydroxytryptophan (L-5HTP).
Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Drug Industry; Drug Therapy, Combination; Humans; Legislation, Drug; Myoclonus; United States | 1983 |
Atypical phenylketonuria due to biopterin deficiency. Early treatment with tetrahydrobiopterin and neurotransmitter precursors, trials of monotherapy.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Clinical Trials as Topic; Humans; Infant; Levodopa; Male; Phenylketonurias; Pteridines | 1982 |
Serotonin precursor effects in tardive dyskinesia.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Serotonin | 1982 |
Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kynurenine; Levodopa; Male; Middle Aged; Myoclonus; Parkinson Disease; Scleroderma, Systemic; Serotonin | 1980 |
Neuropharmacology of progressive myoclonus epilepsy: response to 5-hydroxy-L-tryptophan.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydroxyindoleacetic Acid; Male; Mitochondrial Encephalomyopathies; Pilot Projects; Serotonin | 1995 |
Serotonin-induced cortisol release in CPAP-treated obstructive sleep apnea patients.
Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Enzyme Inhibitors; Female; Humans; Hydrocortisone; Male; Middle Aged; Positive-Pressure Respiration; Radioimmunoassay; Serotonin; Sleep Apnea Syndromes | 1997 |
L-5-hydroxytryptophan does not stimulate LH secretion directly from the pituitary in patients with gonadotrophin releasing hormone deficiency.
Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Hypothalamic Diseases; Hypothalamus; Luteinizing Hormone; Male; Pituitary Gland; Secretory Rate | 1998 |
A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Abnormalities, Multiple; Carbidopa; Child; Child, Preschool; Developmental Disabilities; DNA; DNA Mutational Analysis; Drug Therapy, Combination; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Learning Disabilities; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Syndrome; Tetrahydrofolates; Treatment Outcome; Tryptophan Hydroxylase | 2001 |
Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers.
Topics: 5-Hydroxytryptophan; Adult; Adverse Drug Reaction Reporting Systems; Carbidopa; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Prolactin; Receptors, Presynaptic; Receptors, Serotonin | 2002 |
Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography.
Topics: 5-Hydroxytryptophan; Carbidopa; Carbon Radioisotopes; Carcinoid Tumor; Female; Humans; Image Enhancement; Liver Neoplasms; Lymphatic Metastasis; Male; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adrenocorticotropic Hormone; Adult; Affect; Antidepressive Agents, Second-Generation; Biological Availability; Brain; Carbidopa; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Half-Life; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Nausea; Patient Dropouts; Prolactin; Vomiting; Young Adult | 2008 |
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area Under Curve; Carbidopa; Cross-Over Studies; Domperidone; Dopamine Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Granisetron; Humans; Hydrocortisone; Male; Nausea; Prolactin; Vomiting; Young Adult | 2010 |
Hypothalamic glutamate levels following serotonergic stimulation: a pilot study using 7-Tesla magnetic resonance spectroscopy in healthy volunteers.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Adult; Aspartic Acid; Carbidopa; Choline; Dopamine Agents; Double-Blind Method; Glutamic Acid; Glutamine; Granisetron; Humans; Hypothalamus; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Serotonin Agents; Time Factors; Young Adult | 2010 |
140 other study(ies) available for 5-hydroxytryptophan and carbidopa
Article | Year |
---|---|
Central dopaminergic and serotoninergic systems in the regulation of adrenal tyrosine hydroxylase.
Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Adrenal Glands; Animals; Apomorphine; Bromocriptine; Carbidopa; Clonidine; Dopamine; Drug Interactions; Haloperidol; Hydroxydopamines; Injections, Intraventricular; Kinetics; Levodopa; Male; Piribedil; Pituitary Gland; Rats; Serotonin; Serotonin Antagonists; Splanchnic Nerves; Tyrosine 3-Monooxygenase | 1977 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine | 1977 |
An electron microscopic radioautographic identification of the "enterochromaffin-like" APUD cells in murine oxyntic glands. Demonstration of a metabolic difference between rat and mouse gastric A-like cells.
Topics: 5-Hydroxytryptophan; Animals; APUD Cells; Aromatic Amino Acid Decarboxylase Inhibitors; Autoradiography; Carbidopa; Chromaffin System; Dopa Decarboxylase; Enterochromaffin Cells; Gastric Mucosa; Histamine; Male; Mice; Microscopy, Electron; Rats; Serotonin | 1979 |
Manipulation of brain serotonin in the treatment of myoclonus.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Benzodiazepinones; Brain; Carbidopa; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Infusions, Parenteral; Male; Middle Aged; Myoclonus; Serotonin | 1975 |
Letter: L-dopa and 5-hydroxytryptophan therapy in phenylketonuria with normal phenylalanine-hydroxylase activity.
Topics: 5-Hydroxytryptophan; Carbidopa; Drug Therapy, Combination; Humans; Infant; Levodopa; Phenylalanine Hydroxylase; Phenylketonurias | 1975 |
The effect of biogenic monomines on rapid axonal transport in the rabbit optic nerve.
Topics: 5-Hydroxytryptophan; Animals; Axonal Transport; Biogenic Amines; Carbidopa; Female; Levodopa; Male; Optic Nerve; Pargyline; Rabbits; Time Factors | 1978 |
Central neurochemical factors related to serotonin metabolism and cardiac ventricular vulnerability for repetitive electrical activity.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Dogs; Female; Heart Rate; Heart Ventricles; Male; Phenelzine; Serotonin; Sympathetic Nervous System; Tryptophan; Ventricular Fibrillation | 1978 |
Fenfluramine-induced enhancement of confinement motor activity: an indirect 5-hydroxytryptamine-like action?
Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Brain Chemistry; Carbidopa; Catecholamines; Cinanserin; Female; Fenclonine; Fenfluramine; Metergoline; Methylphenidate; Motor Activity; Rats | 1975 |
Serotonergic stimulation of pituitary-adrenal activity in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Carbidopa; Carbolines; Corticosterone; Cyproheptadine; Female; Fenclonine; Indoles; Metergoline; Mice; Pargyline; Phenyl Ethers; Pituitary-Adrenal System; Propylamines; Quinolines; Quipazine; Spiperone; Tryptophan | 1978 |
[Serotoninergic conception of myoclonic syndromes. (Review)].
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dogs; Electroencephalography; Electromyography; Guinea Pigs; Humans; Hydroxyindoleacetic Acid; Myoclonus; Raphe Nuclei; Reticular Formation; Serotonin; Spinal Cord; Synaptic Transmission | 1979 |
Palatal myoclonus treated with 5-hydroxytryptophan and a decarboxylase-inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Combinations; Humans; Hydrazines; Male; Muscle Contraction; Myoclonus; Palate | 1977 |
Altered excreton of 5-hydroxyindoleacetic acid and glycine in patients with the Lesch-Nyhan disease.
Topics: 5-Hydroxytryptophan; Adolescent; Carbidopa; Child; Child, Preschool; Glycine; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syndrome | 1977 |
Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease.
Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurocognitive Disorders; Probenecid; Serotonin; Tyrosine | 1977 |
Aminergic and thermoregulatory mechanims in hypothalamic regulation of growth hormone in cats.
Topics: 18-Hydroxycorticosterone; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Amines; Blood Glucose; Body Temperature Regulation; Carbidopa; Cats; Growth Hormone; Hypothalamus; Levodopa; Male; Mesencephalon; Norepinephrine; Phenoxybenzamine; Pimozide; Serotonin; Temperature | 1977 |
New approaches in the management of hyperkinetic movement disorders.
Topics: 5-Hydroxytryptophan; Carbidopa; Chorea; Dyskinesia, Drug-Induced; Humans; Movement Disorders; Myoclonus; Propranolol; Receptors, Dopamine; Torticollis; Tranquilizing Agents; Tremor | 1977 |
Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Hypoxia; Male; Myoclonus | 1978 |
Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Carbidopa; Child; Drug Therapy, Combination; Humans; Hydrazines; Lesch-Nyhan Syndrome; Male; Movement Disorders; Self Mutilation; Sleep; Wakefulness | 1978 |
The effects of aromatic amino acid decarboxylase inhibitors on plasma concentrations of 5-hydroxytryptophan in man.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Female; Humans; Kinetics; Male; Middle Aged; Time Factors | 1978 |
Role of peripheral mechanisms in the behavioral effects of 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benserazide; Carbidopa; Male; Proglumide; Rats; Reinforcement Schedule | 1978 |
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Self Mutilation; Serotonin | 1979 |
Canine growth hormone responsiveness during pentobarbital anesthesia: a method for evaluating serotoninergic stimulatory action.
Topics: 5-Hydroxytryptophan; Adrenal Cortex Hormones; Animals; Carbidopa; Dogs; Female; Growth Hormone; Hypoglycemia; Hypothalamus; Insulin; Pentobarbital | 1979 |
Metoclopramide antagonism of 5-hydroxytryptophan-induced "wet-dog" shake behaviour in the rat.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Carbidopa; Haloperidol; Male; Methysergide; Metoclopramide; Quipazine; Rats; Serotonin; Time Factors | 1979 |
L-5-hydroxytryptophan therapy in myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clomipramine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myoclonus | 1979 |
Serotonergic influences on food intake: effect of 5-hydroxytryptophan on parameters of feeding behaviour in deprived and free-feeding rats.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Food Deprivation; Male; Rats; Serotonin; Time Factors | 1979 |
Evidence for a central monoaminergic influence on urinary bladder control mechanism.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Carbidopa; Catecholamines; Dopamine; Levodopa; Male; Norepinephrine; Parasympathetic Nervous System; Pressure; Rats; Spiperone; Urinary Bladder; Urodynamics | 1979 |
Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbidopa; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydrazines; Hypoxia, Brain; Long-Term Care; Male; Middle Aged; Myoclonus; Serotonin; Tryptophan | 1977 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsy, Post-Traumatic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Isocarboxazid; Male; Methysergide; Middle Aged; Myoclonus; Premedication; Tryptophan | 1977 |
Tolerance to the increased locomotor activity produced by L-5-hydroxytryptophan following peripheral decarboxylase inhibition in mice.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Drug Tolerance; Hydrazines; Male; Mice; Motor Activity; Time Factors | 1978 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin | 1975 |
The origin of blood k-hydroxyindoleacetic acid following L-hydrazino-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
The origin of blood 5-hydroxyindoleacetic acid following L-hydrazine-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; Male; Methysergide; Middle Aged; Myoclonus; Serotonin; Syndrome; Tryptophan | 1976 |
Behavior in the Lesch--Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Aggression; Behavior Therapy; Carbidopa; Carboxy-Lyases; Compulsive Behavior; Drug Therapy, Combination; Drug Tolerance; Extinction, Psychological; Feeding Behavior; Humans; Immobilization; Lesch-Nyhan Syndrome; Nutritional Physiological Phenomena; Protective Devices; Self Mutilation | 1976 |
L-5-hydroxytryptophan in treatment of several different syndromes in which myoclonus is prominent.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Child, Preschool; Drug Evaluation; Female; Humans; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Movement; Muscle Contraction; Myoclonus; Syndrome | 1976 |
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Myoclonus; Serotonin | 1976 |
Exposure to high pressure may produce the 5-HT behavioral syndrome in rats.
Topics: 5-Hydroxytryptophan; Animals; Atmospheric Pressure; Behavior, Animal; Brain; Carbidopa; Central Nervous System Diseases; Fenclonine; High Pressure Neurological Syndrome; Hydroxyindoleacetic Acid; Male; Niacinamide; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1990 |
Development of pseudobullous morphea and scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Chronic Disease; Depression; Drug Therapy, Combination; Eosinophilia-Myalgia Syndrome; Humans; Male; Parkinson Disease; Scleroderma, Localized | 1991 |
Palatal myoclonus: treatment with 5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Therapy, Combination; Humans; Male; Myoclonus; Palatal Muscles | 1990 |
Improvement of action myoclonus by an administration of 5-hydroxytryptophan and carbidopa in a child with muscular subsarcolemmal hyperactivity.
Topics: 5-Hydroxytryptophan; Carbidopa; Child, Preschool; Humans; Male; Muscles; Muscular Diseases; Myoclonus | 1990 |
Further evidence for an anomalous regulation of cortical 5-HT2 receptors: studies with 5-HT precursors.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Carbidopa; Cerebral Cortex; Drug Interactions; Ketanserin; Male; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tryptophan | 1990 |
Development of tolerance to the wet-dog shake behaviour but not the increase in seizure threshold induced by L-5-hydroxytryptophan during continued treatment in rats.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Body Weight; Brain Chemistry; Carbidopa; Drug Interactions; Drug Tolerance; Female; Hydroxyindoleacetic Acid; Movement Disorders; Rats; Rats, Inbred Strains; Seizures; Serotonin | 1985 |
Prolactin release after 5-hydroxytryptophan treatment requires an intact neurointermediate pituitary lobe.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dopamine; Hydroxyindoleacetic Acid; Male; Median Eminence; Norepinephrine; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Prolactin; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Middle Aged; Self Mutilation; Suicide, Attempted | 1985 |
Biochemistry and therapeutics of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electroencephalography; gamma-Aminobutyric Acid; Glycine; Humans; Hydroxyindoleacetic Acid; Hypoxia; Methysergide; Models, Biological; Myoclonus; Prednisone; Serotonin; Tryptophan; Valproic Acid | 1986 |
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; Methysergide; Myoclonus | 1986 |
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pigs; Hydroxyindoleacetic Acid; Indoles; Monoamine Oxidase Inhibitors; Myoclonus; Pargyline; Piperazine; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tryptamines; Tryptophan | 1986 |
Neurotransmitter therapy and diet in malignant phenylketonuria.
Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias | 1987 |
Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Cats; Coronary Disease; Female; Heart; Heart Rate; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenelzine; Serotonin; Ventricular Fibrillation | 1987 |
Central versus peripheral effects on temperature preference and body temperature following alteration of 5-HT in maturing mice.
Topics: 5-Hydroxytryptophan; Aging; Amidines; Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Carbidopa; Carboxy-Lyases; Central Nervous System; Double-Blind Method; Drug Interactions; Hydrazines; Injections, Intraperitoneal; Mice; Peripheral Nerves; Piperidines; Serotonin Antagonists | 1989 |
Monoamine oxidase inhibitory properties of milacemide in rats.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Carbidopa; Cerebral Cortex; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Reference Values; Stereotyped Behavior; Tranylcypromine | 1989 |
Serotonin and 5-hydroxytryptophan on blood pressure and renal blood flow in anesthetized rats.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Dose-Response Relationship, Drug; Indomethacin; Male; Rats; Rats, Inbred Strains; Renal Circulation; Serotonin; Vascular Resistance | 1989 |
5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Carbidopa; Hypertension; Male; Rats; Rats, Inbred SHR; Serotonin; Weight Loss | 1989 |
The modulation of head-twitch behaviour by drugs acting on beta-adrenoceptors: evidence for the involvement of both beta 1- and beta 2-adrenoceptors.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Receptors, Adrenergic, beta; Stereotyped Behavior; Time Factors | 1986 |
Folinic acid therapy in treatment of dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Brain; Carbidopa; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Infant, Newborn; Leucovorin; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias | 1987 |
Effects of antidepressant drug combinations on cortical 5-HT2 receptors and wet-dog shakes in rats.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Carbidopa; Cerebral Cortex; Citalopram; Drug Interactions; Fenfluramine; Male; Methoxydimethyltryptamines; Paroxetine; Phenelzine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Time Factors | 1985 |
Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis.
Topics: 5-Hydroxytryptophan; Adult; beta-Endorphin; Carbidopa; Drug Therapy, Combination; Endorphins; Humans; Migraine Disorders; Pain; Sensory Thresholds | 1986 |
The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Carbidopa; Drug Synergism; Fenclonine; Indoles; Lithium; Male; Methoxydimethyltryptamines; Motor Activity; Naphthalenes; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1986 |
p,p'-DDT-induced myoclonus in mice: the effect of enhanced 5-HT neurotransmission.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; DDT; Female; Mice; Mice, Inbred Strains; Myoclonus; Paroxetine; Piperidines; Serotonin; Synaptic Transmission; Tryptophan | 1985 |
Successful long term therapy of biopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Dihydropteridine Reductase; Female; Humans; Infant, Newborn; Levodopa; Liver; Neopterin; Phenylalanine; Phenylalanine Hydroxylase | 1987 |
Drug-induced myoclonus.
Topics: 5-Hydroxytryptophan; Anesthetics; Animals; Anti-Bacterial Agents; Antidepressive Agents; Bismuth; Carbidopa; Electroencephalography; Gasoline; Guinea Pigs; Humans; Hydrocarbons, Brominated; Imipramine; Levodopa; Methysergide; Models, Biological; Myoclonus; Parkinson Disease; Sleep | 1986 |
[Sclerodermiform and poikilodermic syndrome during treatment with carbidopa and 5-hydroxytryptophan. Culture of fibroblasts with biochemical analysis of collagen metabolism].
Topics: 5-Hydroxytryptophan; Carbidopa; Cells, Cultured; Collagen; Drug Therapy, Combination; Fibroblasts; Humans; Scleroderma, Systemic | 1986 |
Prenatal stress increases the behavioral response to serotonin agonists and alters open field behavior in the rat.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Behavior, Animal; Carbidopa; Crowding; Female; Methoxydimethyltryptamines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior; Stress, Psychological | 1986 |
Suppression and potentiation of 5-hydroxytryptophan-induced hypoglycaemia by alpha-monofluoromethyldopa: correlation with the accumulation of 5-hydroxytryptamine in the liver.
Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Brain; Carbidopa; Carboxy-Lyases; Kidney; Lipopolysaccharides; Liver; Male; Methyldopa; Mice; Serotonin | 1987 |
Imipramine administered during an infantile period modifies sex difference in L-5-hydroxytryptophan-induced head shakes in rats.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Behavior, Animal; Carbidopa; Desipramine; Drug Interactions; Female; Imipramine; Male; Rats; Rats, Inbred Strains; Sex Factors | 1987 |
The maturational onset of the 5-HT mediated head twitch in mice.
Topics: 5-Hydroxytryptophan; Aging; Animals; Carbidopa; Female; Humans; Male; Mice; Motor Activity; Pargyline; Serotonin; Tryptophan | 1987 |
Objective quantification of tremor in conscious unrestrained rats, exemplified with 5-hydroxytryptamine-mediated tremor.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Dose-Response Relationship, Drug; Male; Pargyline; Rats; Rats, Inbred Strains; Time Factors; Tremor | 1985 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |
Evidence that the accumulation of 5-hydroxytryptamine in the liver but not in the brain may cause the hypoglycaemia induced by 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Dose-Response Relationship, Drug; Hypoglycemia; Liver; Male; Mice; Pargyline; Serotonin; Time Factors | 1985 |
Formation of serotonin by rat kidneys in vivo.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Carbidopa; Diuresis; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Rats; Rats, Inbred Strains; Renal Circulation; Serotonin | 1985 |
Letter: Treatment of post-anoxic intention myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus | 1974 |
L-dopa hypotension in dogs: evidence for mediation through 5-HT release.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Carbidopa; Chlorpromazine; Depression, Chemical; Dogs; Drug Interactions; Female; Fenclonine; Haloperidol; Heart Rate; Levodopa; Male; Methysergide; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Serotonin; Time Factors; Yohimbine | 1974 |
(S)-norepinephrine in the tissues of mice and rats given racemic erythro-3,4-dihydroxyphenylserine (DOPS).
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Brain Chemistry; Carbidopa; Catechols; Decarboxylation; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Myocardium; Norepinephrine; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Tyramine | 1972 |
Effects of chlorimipramine and protriptyline on the hyperactivity induced by 5-hydroxytryptophan after peripheral decarboxylase inhibition in mice.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Brain; Carbidopa; Carboxy-Lyases; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; Norepinephrine; Sensory Receptor Cells; Serotonin | 1973 |
Monoamine precursors and copulatory behavior in the male rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbidopa; Carboxy-Lyases; Castration; Copulation; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ejaculation; Female; Hydrazines; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nialamide; Pargyline; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone; Time Factors | 1973 |
Studies on DL-5-hydroxytryptophan-induced hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Antidepressive Agents; Blood-Brain Barrier; Brain; Carbidopa; Carboxy-Lyases; Catecholamines; Dibenzazepines; Drug Synergism; Methyltyrosines; Mice; Motor Activity; Neurons; Receptors, Cholinergic; Serotonin; Stimulation, Chemical | 1974 |
L-5-hydroxytryptophan. Correlation between anticonvulsant effect and increases in levels of 5-hydroxyindoles in plasma and brain.
Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain Chemistry; Carbidopa; Electroshock; Female; Hydroxyindoleacetic Acid; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1984 |
Differential effect of carbidopa on the concentration of rat pineal and hypothalamic indoleamines.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Hydroxyindoleacetic Acid; Hypothalamus; Male; Melatonin; Organ Specificity; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1984 |
An electron microscopic radioautographic identification of the APUD endocrine cells in the rat gastric pyloric glands.
Topics: 5-Hydroxytryptophan; Animals; APUD Cells; Autoradiography; Carbidopa; Gastric Mucosa; Male; Microscopy, Electron; Pylorus; Rats | 1981 |
Effects of 5-HT receptor agonists and antagonists on a reflex response to radiant heat in normal and spinally transected rats.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Circadian Rhythm; Hot Temperature; Male; Metergoline; Methiothepin; Mianserin; Neurotransmitter Agents; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord | 1982 |
Identification of the APUD endocrine cells of rat fundic mucosa by means of combined amine fluorescence and electron microscopy.
Topics: 5-Hydroxytryptophan; Amines; Animals; APUD Cells; Carbidopa; Fluorescence; Gastric Mucosa; Male; Microscopy, Electron; Rats; Rats, Inbred Strains | 1984 |
Biopterin synthesis defect. Treatment with L-dopa and 5-hydroxytryptophan compared with therapy with a tetrahydropterin.
Topics: 5-Hydroxytryptophan; Amino Acid Metabolism, Inborn Errors; Biopterins; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Female; Humans; Infant; Levodopa; Neopterin; Neurotransmitter Agents; Pteridines; Pterins | 1984 |
Plasma accumulation of metabolism of orally administered single dose L-5-hydroxytryptophan in man.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Humans; Hydroxyindoleacetic Acid; Intestinal Absorption; Serotonin | 1981 |
Study of serotonin in neuropsychiatric disorders.
Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Middle Aged; Myoclonus; Nervous System Diseases; Psychotic Disorders; Serotonin | 1982 |
Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; Carbidopa; Drug Interactions; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Protein Binding | 1982 |
Kinetics of l-5-hydroxytryptophan in healthy subjects.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Carbidopa; Half-Life; Humans; Hydroxyindoleacetic Acid; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Serotonin | 1982 |
Fluoxetine in the treatment of intention myoclonus.
Topics: 5-Hydroxytryptophan; Adult; Blood Platelets; Carbidopa; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Myoclonus; Propylamines; Serotonin; Time Factors | 1983 |
Alterations in brain 5HT and tryptamine content during indoleamine-induced myoclonus in guinea pigs.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Drug Interactions; Female; Guinea Pigs; Hydroxyindoleacetic Acid; Myoclonus; Pargyline; Serotonin; Tryptamines; Tryptophan | 1983 |
Toxic oil syndrome (Spanish oil disease) and chemically induced scleroderma-like conditions.
Topics: 5-Hydroxytryptophan; Bleomycin; Brassica; Carbidopa; Humans; Oils; Pentazocine; Plastics; Scleroderma, Systemic; Solvents; Vinyl Chloride; Vinyl Compounds | 1984 |
Effect of some serotoninergic agents on the rectal temperature of the domestic fowl (Gallus domesticus).
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Body Temperature; Body Temperature Regulation; Carbidopa; Cattle; Chickens; Citalopram; Cyproheptadine; Fenclonine; Lysergic Acid Diethylamide; Male; Methysergide; Propylamines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors | 1984 |
Evidence that the effects of 5-hydroxytryptophan on the secretion of ACTH and growth hormone in dogs are not mediated by central release of serotonin.
Topics: 11-Hydroxycorticosteroids; 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Benserazide; Carbidopa; Dogs; Female; Growth Hormone; Kinetics; Male; Metergoline; Serotonin | 1982 |
Inhibition of respiratory neural discharges by clonidine and 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Cats; Chemoreceptor Cells; Clonidine; Female; Male; Phenoxybenzamine; Phrenic Nerve; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Respiratory Center; Synaptic Transmission; Tolazoline | 1982 |
Effects of carbidopa on the cerebral accumulation of exogenous L-5-hydroxytryptophan in mice.
Topics: 5-Hydroxytryptophan; Animals; Biological Availability; Brain Chemistry; Carbidopa; Female; Mice; Mice, Inbred Strains | 1984 |
The effects of intraventricular prolactin infusions on pituitary responsiveness to thyrotropin-releasing hormone, 5-hydroxytryptophan or morphine in rhesus monkeys.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Castration; Estradiol; Female; Hydrocortisone; Kinetics; Macaca mulatta; Male; Morphine; Pituitary Gland; Prolactin; Sheep; Thyrotropin-Releasing Hormone | 1983 |
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines | 1983 |
Brain 5-hydroxytryptamine level, metabolism, and binding in E1 mice.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dihydroxyphenylalanine; Mice; Mice, Inbred Strains; Monoamine Oxidase; Physical Stimulation; Serotonin | 1983 |
Effects of manipulating serotonin on the incidence of ovulation in the rat.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Estradiol; Estrogens; Estrus; Female; Fenclonine; Injections, Intraperitoneal; Injections, Subcutaneous; Luteinizing Hormone; Ovulation; Pregnancy; Progesterone; Rats; Serotonin | 1980 |
Serotonin receptor activation in rats previously deprived of REM sleep.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Carbidopa; Male; Methoxydimethyltryptamines; Pargyline; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sleep Deprivation; Sleep, REM; Tryptophan | 1983 |
Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Haloperidol; Male; Methamphetamine; Motor Activity; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine; Tryptophan | 1983 |
Reserpine-induced rigidity in rats: drug effects on muscle tone from corpus striatum and nucleus accumbens.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Carbidopa; Corpus Striatum; Male; Muscle Rigidity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reserpine; Septal Nuclei; Trifluoperazine | 1983 |
Serotonin formation in nonblood-perfused rat kidneys.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Chromatography, High Pressure Liquid; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renal Veins; Serotonin; Vascular Resistance | 1984 |
Locomotion in the rat after 5-hydroxy-L-tryptophan.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Female; Locomotion; Rats | 1984 |
Regulation of prolactin and growth hormone secretion. Site and mechanism of action of thyrotropin-releasing hormone, L-dopa and L-5-hydroxytryptophan in unanesthetized dogs.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Depression, Chemical; Dogs; Female; Growth Hormone; Hormones; Levodopa; Male; Metergoline; Prolactin; Radioimmunoassay; Serotonin; Sex Factors; Stimulation, Chemical; Thyrotropin-Releasing Hormone | 1980 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan | 1982 |
From the NIH: New treatment for myoclonus patients.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Depression, Chemical; Humans; Myoclonus; Serotonin | 1980 |
Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Myoclonus | 1980 |
l-5-Hydroxytryptophan in depression: the first substitution therapy in psychiatry? The treatment of 99 out-patients with 'therapy-resistant' depressions.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aged; Antidepressive Agents; Carbidopa; Depression; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Sex Factors | 1980 |
Evidence for a peripheral effect of sertonin or metabolites in 5-hydroxytryptophan-induced hypothermia.
Topics: 5-Hydroxytryptophan; Amidines; Animals; Benserazide; Body Temperature; Carbidopa; Dose-Response Relationship, Drug; Male; Phenyl Ethers; Rats; Serotonin; Temperature; Time Factors | 1980 |
Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clonazepam; Diarrhea; Drug Therapy, Combination; Electroencephalography; Electromyography; Humans; Middle Aged; Myoclonus; Nausea; Phenobarbital; Serotonin | 1980 |
Drug-related scleroderma-like illness. The Fine page.
Topics: 5-Hydroxytryptophan; Carbidopa; Drug Combinations; Humans; Kynurenine; Scleroderma, Systemic | 1981 |
Peripheral conversion of L-5-hydroxytryptophan to serotonin induces drinking in rats.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drinking Behavior; Female; Methysergide; Rats; Receptors, Serotonin; Serotonin | 1981 |
Serotonin regulation of corticoid secretion in infant rats.
Topics: 5-Hydroxytryptophan; Adrenal Cortex; Animals; Animals, Newborn; Carbidopa; Corticosterone; Dose-Response Relationship, Drug; Fluoxetine; Rats; Serotonin; Weaning | 1981 |
Long-term infusion of L-5-hydroxytryptophan increases brain serotonin turnover and decreases blood pressure in normotensive rats.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain; Carbidopa; Catecholamines; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1982 |
Serotonergic approaches to the modification of behavior in the Lesch-Nyhan Syndrome.
Topics: 5-Hydroxytryptophan; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Lesch-Nyhan Syndrome; Male; Videotape Recording | 1980 |
Segmental action and stimuli-sensitive myoclonus with acute onset. A case report.
Topics: 5-Hydroxytryptophan; Acute Disease; Adult; Angiography; Carbidopa; Carotid Arteries; Cerebrovascular Circulation; Clonazepam; Diazepam; Electric Stimulation; Electroencephalography; Humans; Male; Myoclonus; Vertebral Artery | 1980 |
Survival of neonatal rats during hypoxia after monoamine stimulating agents.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Apomorphine; Biogenic Amines; Carbidopa; Female; Hypoxia; Levodopa; Pregnancy; Rats; Rats, Inbred Strains; Time Factors | 1982 |
[Oral bioavailability of an L-5-HTP/carbidopa tablet].
Topics: 5-Hydroxytryptophan; Animals; Biological Availability; Carbidopa; Dogs; Drug Combinations; Male; Tablets | 1982 |
Pharmacological evidence that stimulation of central serotonergic pathways increases renin secretion.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carbidopa; Denervation; Dogs; Female; Kidney; Male; Metergoline; Renin; Serotonin; Tryptophan | 1980 |
Dopamine and serotonin turnover rate in the retina of rabbit, rat, goldfish, and Eugerres plumieri: light effects in goldfish and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Carbidopa; Dopamine; Fenclonine; Goldfish; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Light; Male; Methyltyrosines; Pargyline; Perciformes; Rabbits; Rats; Rats, Sprague-Dawley; Retina; Serotonin; Species Specificity | 1994 |
Low responsiveness to agents evoking 5-HT2 receptor-mediated behaviors in Sardinian alcohol-preferring rats.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Amphetamines; Animals; Behavior, Animal; Carbidopa; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Peptide Fragments; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Agents; Serotonin Receptor Agonists; Substance P | 1995 |
Abnormal serotonergic stimulation of cortisol production in obstructive sleep apnea.
Topics: 5-Hydroxytryptophan; Adult; Body Mass Index; Brain; Carbidopa; Case-Control Studies; Humans; Hydrocortisone; Male; Receptors, Serotonin; Serotonin; Sleep Apnea Syndromes; Time Factors; Wakefulness | 1995 |
Effects of glucocorticoids on 5-HT1A presynaptic function in the mouse.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Carbidopa; Corticosterone; Dose-Response Relationship, Drug; Glucocorticoids; Male; Mice; Receptors, Presynaptic; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior | 1994 |
Tetrahydrobiopterin deficiency and an international database of patients.
Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Information Systems; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pterins; Registries | 1993 |
Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carrier Proteins; Corpus Striatum; Dopamine; Drug Synergism; Fluoxetine; Frontal Lobe; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tetrodotoxin | 1996 |
Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
Topics: 5-Hydroxytryptophan; Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Binding Sites; Carbidopa; Crystallography, X-Ray; Dopa Decarboxylase; Drug Design; Humans; Kidney; Levodopa; Ligands; Models, Molecular; Parkinson Disease; Pliability; Protein Structure, Secondary; Swine | 2001 |
Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis.
Topics: 5-Hydroxytryptophan; Animals; Antiemetics; Behavior, Animal; Carbidopa; Central Nervous System; Dopamine Agents; Dose-Response Relationship, Drug; Dronabinol; Emetics; Female; Male; Peripheral Nervous System; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews | 2004 |
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures | 2005 |
Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy.
Topics: 5-Hydroxytryptophan; Adolescent; Alcohol Oxidoreductases; Antidepressive Agents, Second-Generation; Carbidopa; Child; Dopamine Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Levodopa; Male; Metabolism, Inborn Errors; Treatment Outcome | 2006 |
Serum prolactin as a tool for the follow-up of treated DHPR-deficient patients.
Topics: 5-Hydroxytryptophan; Aromatic Amino Acid Decarboxylase Inhibitors; Biomarkers; Carbidopa; Child, Preschool; Dietary Proteins; Dihydropteridine Reductase; Dopa Decarboxylase; Dopamine Agents; Drug Monitoring; Drug Therapy, Combination; Enzyme Inhibitors; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Italy; Levodopa; Monoamine Oxidase Inhibitors; Mutation; Neonatal Screening; Neurologic Examination; Phenotype; Phenylketonurias; Prolactin; Selegiline; Time Factors; Treatment Outcome | 2008 |
How physician obesity specialists use drugs to treat obesity.
Topics: 5-Hydroxytryptophan; Anti-Obesity Agents; Carbidopa; Drug Combinations; Drug Labeling; Drug Therapy, Combination; Drug Utilization; Guideline Adherence; Health Care Surveys; Humans; Medicine; Obesity; Phentermine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prescription Drugs; Retrospective Studies; Specialization; Surveys and Questionnaires; Time Factors; Treatment Outcome; United States; Weight Loss | 2009 |
5-HT precursor loading, but not 5-HT receptor agonists, increases motor function after spinal cord contusion in adult rats.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Cervical Vertebrae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Enzyme Inhibitors; Exercise Test; Exploratory Behavior; Female; Fenfluramine; Hindlimb; Laminectomy; Motor Activity; Movement Disorders; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Spinal Cord Injuries; Stereotyped Behavior; Time Factors; Tremor; Up-Regulation | 2010 |
[(11)C]5-HTP and microPET are not suitable for pharmacodynamic studies in the rodent brain.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Carbon Radioisotopes; Enzyme Inhibitors; Hydrazines; Male; Models, Biological; Positron-Emission Tomography; Rats; Rats, Wistar; Sensitivity and Specificity; Serotonin; Tissue Distribution; Tryptophan | 2014 |
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine | 2014 |
Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Gene Expression Regulation; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Motor Activity; Norepinephrine; Serotonin; Time Factors; Tryptophan Hydroxylase | 2015 |
Spinal Cord Hemisection Facilitates Aromatic L-Amino Acid Decarboxylase Cells to Produce Serotonin in the Subchronic but Not the Chronic Phase.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Chronic Disease; Hindlimb; Male; Nerve Fibers; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord Injuries; Tail; Thoracic Vertebrae | 2015 |
What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa.
Topics: 5-Hydroxytryptophan; Adolescent; Anti-Dyskinesia Agents; Carbidopa; Diseases in Twins; Dopamine Agonists; Drug Combinations; Dystonia; Female; Humans; Levodopa; Male; Metabolism, Inborn Errors; Psychomotor Disorders; Serotonin Agents | 2016 |
Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.
Topics: 5-Hydroxytryptophan; Adult; Atrophy; Carbidopa; Central Nervous System Agents; Fatal Outcome; Female; Humans; Paraparesis; Pregnancy; Pregnancy Complications; Spinal Cord Diseases; Young Adult | 2017 |
Improvement of Self-Injury With Dopamine and Serotonin Replacement Therapy in a Patient With a Hemizygous PAK3 Mutation: A New Therapeutic Strategy for Neuropsychiatric Features of an Intellectual Disability Syndrome.
Topics: 5-Hydroxytryptophan; Adolescent; Brain; Carbidopa; Dopamine; Drug Combinations; Humans; Intellectual Disability; Levodopa; Male; Mutation; p21-Activated Kinases; Psychotropic Drugs; Self-Injurious Behavior; Serotonin; Syndrome | 2018 |
Anorectic interaction and safety of 5-hydroxytryptophan/carbidopa plus phentermine or diethylpropion in rat.
Topics: 5-Hydroxytryptophan; Animals; Appetite Depressants; Biomarkers, Pharmacological; Carbidopa; Cardiovascular System; Diethylpropion; Drug Combinations; Drug Dosage Calculations; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Obesity; Phentermine; Rats | 2021 |
Acute treatment with 5-hydroxytryptophan increases social approach behaviour but does not activate serotonergic neurons in the dorsal raphe nucleus in juvenile male BALB/c mice: A model of human disorders with deficits of sociability.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Choice Behavior; Dorsal Raphe Nucleus; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Serotonergic Neurons; Serotonin; Social Behavior; Tryptophan Hydroxylase | 2022 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |