Page last updated: 2024-09-04

5-hydroxypyrazinoic acid and pyrazinamide

5-hydroxypyrazinoic acid has been researched along with pyrazinamide in 6 studies

Compound Research Comparison

Studies
(5-hydroxypyrazinoic acid)
Trials
(5-hydroxypyrazinoic acid)
Recent Studies (post-2010)
(5-hydroxypyrazinoic acid)
Studies
(pyrazinamide)
Trials
(pyrazinamide)
Recent Studies (post-2010) (pyrazinamide)
7133,6263201,113

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duwoos, H; Lacroix, C; Lafont, O; Phan Hoang, T; Tranvouez, JL1
Guyonnaud, C; Lacroix, C; Lafont, O; Laine, G; Menager, S; Poncet, P; Ray, M1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
André, D; Chabenat, C; Lafont, O; Mehmedagic, A; Ménager, S; Tharasse, C; Vérité, P1
Sanyal, M; Shah, JV; Shah, PA; Sharma, P; Shrivastav, PS1
Chaturvedi, S; Dubey, D; Guleria, A; Keshari, AK; Kumar, D; Kumar, U; Prakash, A; Rai, A; Raj, V; Rawat, A; Saha, S; Singh, AK1

Trials

1 trial(s) available for 5-hydroxypyrazinoic acid and pyrazinamide

ArticleYear
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol

1995

Other Studies

5 other study(ies) available for 5-hydroxypyrazinoic acid and pyrazinamide

ArticleYear
Pharmacokinetics of pyrazinamide and its metabolites in patients with hepatic cirrhotic insufficiency.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Liver Cirrhosis; Liver Function Tests; Male; Pyrazinamide

1990
[Microdetermination of pyrazinamide and its metabolites (pyrazinoic acid, 5-hydroxypyrazinoic acid, 5-hydroxypyrazinamide and pyrazinuric acid) in plasma and urine with liquid chromatography].
    Journal of chromatography, 1987, Nov-27, Volume: 422

    Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Indicators and Reagents; Pyrazinamide; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1987
Determination of pyrazinamide and its main metabolites in rat urine by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2

    Topics: Animals; Antitubercular Agents; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Pyrazinamide; Rats; Rats, Sprague-Dawley; Reproducibility of Results

1997
An improved LC-MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5-hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Apr-01, Volume: 1017-1018

    Topics: Calibration; Chromatography, Liquid; Humans; Pyrazinamide; Quality Control; Reference Standards; Tandem Mass Spectrometry

2016
Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid.
    Human & experimental toxicology, 2018, Volume: 37, Issue:4

    Topics: Administration, Oral; Animals; Antitubercular Agents; Biomarkers; Biotransformation; Chemical and Drug Induced Liver Injury; Liver; Male; Metabolomics; Microscopy, Electron, Scanning; Multivariate Analysis; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Pyrazinamide; Rats, Wistar; Risk Assessment; Time Factors; Toxicity Tests

2018