5-hydroxypyrazinamide has been researched along with allopurinol in 5 studies
| Studies (5-hydroxypyrazinamide) | Trials (5-hydroxypyrazinamide) | Recent Studies (post-2010) (5-hydroxypyrazinamide) | Studies (allopurinol) | Trials (allopurinol) | Recent Studies (post-2010) (allopurinol) |
|---|---|---|---|---|---|
| 12 | 1 | 0 | 15,096 | 743 | 3,363 |
| Protein | Taxonomy | 5-hydroxypyrazinamide (IC50) | allopurinol (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | Rattus norvegicus (Norway rat) | 3.3765 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 3.1861 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 5.0758 | |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | 8.69 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T | 2 |
| Carini, M; Carlo, A; Facino, RM; Pitrè, D | 1 |
| Hada, T; Higashino, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T | 1 |
| Hada, T; Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Suda, M; Takahashi, S; Yamamoto, T | 1 |
5 other study(ies) available for 5-hydroxypyrazinamide and allopurinol
| Article | Year |
|---|---|
Study of the metabolism of pyrazinamide using a high-performance liquid chromatographic analysis of urine samples.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Humans; Pyrazinamide; Xanthine Oxidase; Xanthines | 1987 |
In vitro conversion of pyrazinamide into 5-hydroxypyrazinamide and that of pyrazinoic acid into 5-hydroxypyrazinoic acid by xanthine oxidase from human liver.
Topics: Humans; Liver; NAD; Pyrazinamide; Xanthine Oxidase | 1987 |
In vitro biotransformation of pyrazinamide by rat liver: identification of a new metabolite.
Topics: Animals; Biotransformation; Chromatography, Thin Layer; Hydroxylation; In Vitro Techniques; Liver; Male; Mass Spectrometry; Pyrazinamide; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1981 |
In vitro and in vivo study on the conversion of allopurinol and pyrazinamide.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Biotransformation; Liver; Male; Oxidation-Reduction; Oxypurinol; Pyrazinamide; Rats; Rats, Wistar; Triazines; Xanthine Dehydrogenase; Xanthine Oxidase | 1994 |
In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Benzamidines; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Oxypurinol; Pyrazinamide; Rats; Rats, Wistar; Triazines | 1993 |