5-hydroxymethylomeprazole has been researched along with mephenytoin in 3 studies
| Studies (5-hydroxymethylomeprazole) | Trials (5-hydroxymethylomeprazole) | Recent Studies (post-2010) (5-hydroxymethylomeprazole) | Studies (mephenytoin) | Trials (mephenytoin) | Recent Studies (post-2010) (mephenytoin) |
|---|---|---|---|---|---|
| 54 | 17 | 15 | 580 | 35 | 32 |
| Protein | Taxonomy | 5-hydroxymethylomeprazole (IC50) | mephenytoin (IC50) |
|---|---|---|---|
| Cytochrome P450 2C19 | Homo sapiens (human) | 1.185 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiba, K; Ishizaki, T; Kobayashi, K; Lee, KH; Shin, SG; Sohn, DR | 1 |
| Bertilsson, L; Chang, M; Dahl, ML; Götharson, E; Tybring, G | 1 |
| Chow, AH; Chow, MS; Tomlinson, B; Waye, MM; Yin, OQ | 1 |
1 trial(s) available for 5-hydroxymethylomeprazole and mephenytoin
| Article | Year |
|---|---|
Omeprazole as a CYP2C19 marker in Chinese subjects: assessment of its gene-dose effect and intrasubject variability.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Asian People; Cross-Over Studies; Cytochrome P-450 CYP2C19; Enzyme Inhibitors; Gene Dosage; Humans; Hydroxylation; Male; Mephenytoin; Mixed Function Oxygenases; Omeprazole; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values | 2004 |
2 other study(ies) available for 5-hydroxymethylomeprazole and mephenytoin
| Article | Year |
|---|---|
Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation recruited from an Oriental population.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Humans; Hydroxylation; Korea; Male; Mephenytoin; Omeprazole | 1992 |
Use of omeprazole as a probe drug for CYP2C19 phenotype in Swedish Caucasians: comparison with S-mephenytoin hydroxylation phenotype and CYP2C19 genotype.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Female; Genotype; Humans; Hydroxylation; Male; Mephenytoin; Middle Aged; Mixed Function Oxygenases; Molecular Probes; Omeprazole; Pharmacogenetics; Phenotype; Sweden; White People | 1995 |