Page last updated: 2024-09-03

5-hydroxymethylomeprazole and losartan

5-hydroxymethylomeprazole has been researched along with losartan in 2 studies

Compound Research Comparison

Studies
(5-hydroxymethylomeprazole)
Trials
(5-hydroxymethylomeprazole)
Recent Studies (post-2010)
(5-hydroxymethylomeprazole)
Studies
(losartan)
Trials
(losartan)
Recent Studies (post-2010) (losartan)
5417157,2311,2452,118

Protein Interaction Comparison

ProteinTaxonomy5-hydroxymethylomeprazole (IC50)losartan (IC50)
Bile salt export pumpHomo sapiens (human)9.01
Cytochrome P450 2C9 Homo sapiens (human)2.882
Angiotensin-converting enzyme Homo sapiens (human)0.019
Atrial natriuretic peptide receptor 3Homo sapiens (human)0.0018
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.019
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0247
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0234
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0032
Type-1 angiotensin II receptorHomo sapiens (human)0.047
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.025
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0118
Type-2 angiotensin II receptorHomo sapiens (human)0.019
Platelet glycoprotein VIHomo sapiens (human)4
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.1481
Type-1 angiotensin II receptorCavia porcellus (domestic guinea pig)0.018
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.2884

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertilsson, L; Eliasson, E; Masquelier, M; Ostervall, J; Otto, S; Rosenborg, S; Stenberg, M; Yue, QY1
Kim, DH; Oh, KS; Park, SJ; Shin, JG; Shinde, DD1

Trials

1 trial(s) available for 5-hydroxymethylomeprazole and losartan

ArticleYear
Clinically significant CYP2C inhibition by noscapine but not by glucosamine.
    Clinical pharmacology and therapeutics, 2010, Volume: 88, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anticoagulants; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Interactions; Female; Glucosamine; Humans; Losartan; Male; Middle Aged; Noscapine; Omeprazole; Phenotype; Warfarin; Young Adult

2010

Other Studies

1 other study(ies) available for 5-hydroxymethylomeprazole and losartan

ArticleYear
High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, May-01, Volume: 895-896

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Caffeine; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Drug Stability; Humans; Imidazoles; Linear Models; Liquid-Liquid Extraction; Losartan; Omeprazole; Pharmaceutical Preparations; Reproducibility of Results; Tandem Mass Spectrometry; Tetrazoles; Theophylline

2012