Page last updated: 2024-09-05

5-hydroxymethyldeoxycytidine monophosphate and thymidine

5-hydroxymethyldeoxycytidine monophosphate has been researched along with thymidine in 6 studies

Compound Research Comparison

Studies
(5-hydroxymethyldeoxycytidine monophosphate)
Trials
(5-hydroxymethyldeoxycytidine monophosphate)
Recent Studies (post-2010)
(5-hydroxymethyldeoxycytidine monophosphate)
Studies
(thymidine)
Trials
(thymidine)
Recent Studies (post-2010) (thymidine)
2702333,4102411,117

Protein Interaction Comparison

ProteinTaxonomy5-hydroxymethyldeoxycytidine monophosphate (IC50)thymidine (IC50)
Thymidine kinase Macacine alphaherpesvirus 14.1
Thymidine kinase, cytosolicHomo sapiens (human)0.614
Thymidine kinaseHuman alphaherpesvirus 1 strain SC161
Sterol O-acyltransferase 1Cricetulus griseus (Chinese hamster)1.8

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Brooks, PJ; Fisher, DE; Guerrero, C; Liu, S; Mitra, D; Song, H; Su, Y; Wang, J; Wang, Y; Zeng, Y1
Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R1
El Safadi, Y; Isel, C; Laumond, G; Marquet, R; Moog, C; Paillart, JC; Smyth, RP; Vivet-Boudou, V1
Bajrami, I; Boulton, SJ; Carell, T; Fugger, K; Goldstone, R; Hewitt, G; Kelly, G; Kunzelmann, S; MacRae, J; Patel, H; Silva Dos Santos, M; Taylor, IA; West, SC; Young, SJ1
Peña-Gómez, MJ; Rosado, IV; Suárez-Pizarro, M1
García-Calderón, CB; Klimašauskas, S; Moreno-Gordillo, P; Narmontė, M; Peña-Gómez, MJ; Rosado, IV; Rukšėnaitė, A1

Other Studies

6 other study(ies) available for 5-hydroxymethyldeoxycytidine monophosphate and thymidine

ArticleYear
Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.
    Nucleic acids research, 2013, Volume: 41, Issue:13

    Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deoxycytidine; Dioxygenases; DNA; DNA-Binding Proteins; HEK293 Cells; Humans; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Skin; Tandem Mass Spectrometry; Thymidine

2013
Comparison of the absolute level of epigenetic marks 5-methylcytosine, 5-hydroxymethylcytosine, and 5-hydroxymethyluracil between human leukocytes and sperm.
    Biology of reproduction, 2014, Volume: 91, Issue:3

    Topics: 5-Methylcytosine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Leukocytes; Male; Pentoxyl; Poland; Spectrometry, Mass, Electrospray Ionization; Spermatozoa; Tandem Mass Spectrometry; Thymidine; Up-Regulation

2014
Evaluation of anti-HIV-1 mutagenic nucleoside analogues.
    The Journal of biological chemistry, 2015, Jan-02, Volume: 290, Issue:1

    Topics: Anti-HIV Agents; Base Pair Mismatch; Base Pairing; Base Sequence; Deoxycytidine; Drug Design; High-Throughput Screening Assays; HIV Reverse Transcriptase; HIV-1; Molecular Sequence Data; Mutagenesis; Mutagens; Nucleic Acid Denaturation; Predictive Value of Tests; Reverse Transcriptase Inhibitors; Reverse Transcription; Thermodynamics; Thymidine; Time Factors

2015
Targeting the nucleotide salvage factor DNPH1 sensitizes
    Science (New York, N.Y.), 2021, 04-09, Volume: 372, Issue:6538

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; CRISPR-Cas Systems; Deoxycytidine Monophosphate; Deoxyuracil Nucleotides; DNA Breaks, Double-Stranded; DNA Replication; DNA, Neoplasm; Drug Resistance, Neoplasm; Genes, BRCA1; Humans; Hydrolysis; N-Glycosyl Hydrolases; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Synthetic Lethal Mutations; Thymidine; Uracil-DNA Glycosidase

2021
XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2'-Deoxycytidine and 5-Hydroxymethyl-2'-Deoxyuridine.
    International journal of molecular sciences, 2022, Jan-14, Volume: 23, Issue:2

    Topics: 5-Methylcytosine; Cell Line; Cell Survival; Deoxycytidine; DNA Damage; DNA Demethylation; DNA Replication; Epigenesis, Genetic; Genomic Instability; Humans; Replication Origin; Thymidine; X-ray Repair Cross Complementing Protein 1

2022
FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine.
    Cell death & disease, 2022, 05-27, Volume: 13, Issue:5

    Topics: Deoxycytidine; DNA Demethylation; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Humans; Thymidine

2022