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5-hydroxyflavone and chrysin

5-hydroxyflavone has been researched along with chrysin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's5 (27.78)29.6817
2010's11 (61.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Dekermendjian, K; Kahnberg, P; Liljefors, T; Nielsen, M; Sterner, O; Witt, MR1
Chi, YS; Dao, TT; Kim, HP; Kim, J; Kim, S; Park, H1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Cavaleiro, JA; Fernandes, E; Gomes, A; Lima, JL; Pinto, DC; Santos, CM; Silva, AM1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Amić, D; Lucić, B1
Arioka, S; Hinou, H; Nishimura, S; Sakagami, M; Takemoto, H; Togame, H; Uematsu, R; Yamaguchi, H1
Ataide Martins, JP; Borges de Melo, E; Castro Ferreira, MM; Friozi, MC; Marinho Jorge, TC1
Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K1
Arnold, CL; Dupart, PS; Foroozesh, M; Jiang, Q; Liu, J; Skripnikova, EV; Sridhar, J; Taylor, SF; Wang, Y; Zhao, M1
Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Govil, G; Joshi, A; Joshi, UJ; Sinha, R; Srivastava, S1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1
Dutour, R; Poirier, D1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1
Ferreira, D; Hale, AL; Herath, W; Khan, IA; Mikell, JR1
Guengerich, FP; Kakimoto, K; Katahira, J; Kim, D; Komori, M; Lim, YR; Murayama, N; Nagayoshi, H; Shimada, T; Takenaka, S; Tsujino, M; Yamazaki, H1

Reviews

1 review(s) available for 5-hydroxyflavone and chrysin

ArticleYear
Inhibitors of cytochrome P450 (CYP) 1B1.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2017

Other Studies

17 other study(ies) available for 5-hydroxyflavone and chrysin

ArticleYear
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: Animals; Binding Sites; Brain; Flavonoids; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Reproducibility of Results; Structure-Activity Relationship

1999
Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.
    Bioorganic & medicinal chemistry letters, 2004, Mar-08, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flavonoids; Isoenzymes; Mice; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins

2004
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Antioxidants; Chromones; Free Radical Scavengers; Free Radicals; Reactive Nitrogen Species; Reactive Oxygen Species; Styrenes

2007
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.
    Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4

    Topics: Base Sequence; DNA Primers; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycoproteins; Neuraminidase; Recombinant Proteins; Structure-Activity Relationship; Trypanosoma cruzi

2010
Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Algorithms; Antimutagenic Agents; Flavonoids; Fluorenes; Least-Squares Analysis; Models, Biological; Models, Molecular; Mutagens; Quantitative Structure-Activity Relationship; Salmonella typhimurium

2010
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2010
Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.
    Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10

    Topics: Aryl Hydrocarbon Hydroxylases; Catalytic Domain; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Data Interpretation, Statistical; Enzyme Inhibitors; Flavones; Fluorometry; Humans; Kinetics; Ligands; Models, Molecular; Small Molecule Libraries; Spectrometry, Fluorescence; Structure-Activity Relationship

2013
Modulation of human neutrophils' oxidative burst by flavonoids.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction

2013
Inhibition of LOX by flavonoids: a structure-activity relationship study.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Localization and interaction of hydroxyflavones with lipid bilayer model membranes: a study using DSC and multinuclear NMR.
    European journal of medicinal chemistry, 2014, Jun-10, Volume: 80

    Topics: Biphenyl Compounds; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Flavones; Free Radical Scavengers; Humans; Hydroxides; Lipid Bilayers; Magnetic Resonance Spectroscopy; Picrates; Structure-Activity Relationship

2014
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020
Microbial metabolism part 9. Structure and antioxidant significance of the metabolites of 5,7-dihydroxyflavone (chrysin), and 5- and 6-hydroxyflavones.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:4

    Topics: Antioxidants; Flavonoids; Fungi; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Conformation; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared

2008
Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes.
    Chemical research in toxicology, 2019, 06-17, Volume: 32, Issue:6

    Topics: Cytochrome P-450 Enzyme System; Flavones; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction

2019